Rajaram Gopalakrishnan - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Molecular Biology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Blixt N, Norton A, Zhang A, Aparicio C, Prasad H, Gopalakrishnan R, Jensen ED, Mansky KC. Loss of myocyte enhancer factor 2 expression in osteoclasts leads to opposing skeletal phenotypes. Bone. 115466. PMID 32512162 DOI: 10.1016/J.Bone.2020.115466  0.43
2020 Leightner AC, Mello Guimaraes Meyers C, Evans MD, Mansky KC, Gopalakrishnan R, Jensen ED. Regulation of Osteoclast Differentiation at Multiple Stages by Protein Kinase D Family Kinases. International Journal of Molecular Sciences. 21. PMID 32033440 DOI: 10.3390/Ijms21031056  0.457
2019 Huntley R, Jensen E, Gopalakrishnan R, Mansky KC. Bone morphogenetic proteins: Their role in regulating osteoclast differentiation. Bone Reports. 10: 100207. PMID 31193008 DOI: 10.1016/J.Bonr.2019.100207  0.438
2018 Tasca A, Astleford K, Blixt NC, Jensen ED, Gopalakrishnan R, Mansky KC. SMAD1/5 signaling in osteoclasts regulates bone formation via coupling factors. Plos One. 13: e0203404. PMID 30188920 DOI: 10.1371/Journal.Pone.0203404  0.484
2017 Blixt NC, Faulkner BK, Astleford K, Lelich R, Schering J, Spencer E, Gopalakrishnan R, Jensen ED, Mansky KC. Class II and IV HDACs function as inhibitors of osteoclast differentiation. Plos One. 12: e0185441. PMID 28953929 DOI: 10.1371/Journal.Pone.0185441  0.365
2017 Tasca A, Astleford K, Lederman A, Jensen ED, Lee BS, Gopalakrishnan R, Mansky KC. Regulation of Osteoclast Differentiation by Myosin X. Scientific Reports. 7: 7603. PMID 28790434 DOI: 10.1038/S41598-017-07855-9  0.441
2016 Ouattara A, Cooke D, Gopalakrishnan R, Huang TH, Ables GP. Methionine restriction alters bone morphology and affects osteoblast differentiation. Bone Reports. 5: 33-42. PMID 28326345 DOI: 10.1016/J.Bonr.2016.02.002  0.443
2015 Thumbigere-Math V, Michalowicz BS, Hughes PJ, Basi DL, Tsai ML, Swenson KK, Rockwell L, Gopalakrishnan R. Serum Markers of Bone Turnover and Angiogenesis in Patients With Bisphosphonate-Related Osteonecrosis of the Jaw After Discontinuation of Long-Term Intravenous Bisphosphonate Therapy. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. PMID 26501428 DOI: 10.1016/J.Joms.2015.09.028  0.332
2015 Stemig M, Astelford K, Emery A, Cho JJ, Allen B, Huang TH, Gopalakrishnan R, Mansky KC, Jensen ED. Deletion of histone deacetylase 7 in osteoclasts decreases bone mass in mice by interactions with MITF. Plos One. 10: e0123843. PMID 25875108 DOI: 10.1371/Journal.Pone.0123843  0.486
2015 Huntley R, Davydova J, Petryk A, Billington CJ, Jensen ED, Mansky KC, Gopalakrishnan R. The Function of Twisted Gastrulation in Regulating Osteoclast Differentiation is Dependent on BMP Binding. Journal of Cellular Biochemistry. 116: 2239-46. PMID 25808976 DOI: 10.1002/Jcb.25174  0.449
2015 Tasca A, Stemig M, Broege A, Huang B, Davydova J, Zwijsen A, Umans L, Jensen ED, Gopalakrishnan R, Mansky KC. Smad1/5 and Smad4 expression are important for osteoclast differentiation. Journal of Cellular Biochemistry. 116: 1350-60. PMID 25711193 DOI: 10.1002/Jcb.25092  0.423
2015 Billington CJ, Schmidt B, Marcucio RS, Hallgrimsson B, Gopalakrishnan R, Petryk A. Impact of retinoic acid exposure on midfacial shape variation and manifestation of holoprosencephaly in Twsg1 mutant mice. Disease Models & Mechanisms. 8: 139-46. PMID 25468951 DOI: 10.1242/Dmm.018275  0.347
2014 Khammanivong A, Gopalakrishnan R, Dickerson EB. SMURF1 silencing diminishes a CD44-high cancer stem cell-like population in head and neck squamous cell carcinoma. Molecular Cancer. 13: 260. PMID 25471937 DOI: 10.1186/1476-4598-13-260  0.354
2013 Mansky KC, Jensen ED, Davidova J, Yamamoto M, Gopalakrishnan R. Protein kinase D promotes in vitro osteoclast differentiation and fusion. The Journal of Biological Chemistry. 288: 9826-34. PMID 23430742 DOI: 10.1074/Jbc.M112.444133  0.442
2013 Forsman CL, Ng BC, Heinze RK, Kuo C, Sergi C, Gopalakrishnan R, Yee D, Graf D, Schwertfeger KL, Petryk A. BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization Developmental Biology. 373: 95-106. PMID 23103586 DOI: 10.1016/J.Ydbio.2012.10.007  0.378
2011 Billington CJ, Fiebig JE, Forsman CL, Pham L, Burbach N, Sun M, Jaskoll T, Mansky K, Gopalakrishnan R, O'Connor MB, Mueller TD, Petryk A. Glycosylation of Twisted Gastrulation is Required for BMP Binding and Activity during Craniofacial Development. Frontiers in Physiology. 2: 59. PMID 21941513 DOI: 10.3389/Fphys.2011.00059  0.377
2011 Basi DL, Hughes PJ, Thumbigere-Math V, Sabino M, Mariash A, Lunos SA, Jensen E, Gopalakrishnan R. Matrix metalloproteinase-9 expression in alveolar extraction sockets of Zoledronic acid-treated rats. Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons. 69: 2698-707. PMID 21752506 DOI: 10.1016/J.Joms.2011.02.065  0.366
2011 Billington CJ, Ng B, Forsman C, Schmidt B, Bagchi A, Symer DE, Schotta G, Gopalakrishnan R, Sarver AL, Petryk A. The molecular and cellular basis of variable craniofacial phenotypes and their genetic rescue in Twisted gastrulation mutant mice. Developmental Biology. 355: 21-31. PMID 21549111 DOI: 10.1016/J.Ydbio.2011.04.026  0.334
2011 Pham L, Beyer K, Jensen ED, Rodriguez JS, Davydova J, Yamamoto M, Petryk A, Gopalakrishnan R, Mansky KC. Bone morphogenetic protein 2 signaling in osteoclasts is negatively regulated by the BMP antagonist, twisted gastrulation. Journal of Cellular Biochemistry. 112: 793-803. PMID 21328453 DOI: 10.1002/Jcb.23003  0.496
2011 Pham L, Kaiser B, Romsa A, Schwarz T, Gopalakrishnan R, Jensen ED, Mansky KC. HDAC3 and HDAC7 have opposite effects on osteoclast differentiation. The Journal of Biological Chemistry. 286: 12056-65. PMID 21324898 DOI: 10.1074/Jbc.M110.216853  0.387
2010 Samaan G, Yugo D, Rajagopalan S, Wall J, Donnell R, Goldowitz D, Gopalakrishnan R, Venkatachalam S. Foxn3 is essential for craniofacial development in mice and a putative candidate involved in human congenital craniofacial defects. Biochemical and Biophysical Research Communications. 400: 60-5. PMID 20691664 DOI: 10.1016/J.Bbrc.2010.07.142  0.33
2010 Sun M, Forsman C, Sergi C, Gopalakrishnan R, O'Connor MB, Petryk A. The expression of twisted gastrulation in postnatal mouse brain and functional implications Neuroscience. 169: 920-931. PMID 20493240 DOI: 10.1016/J.Neuroscience.2010.05.026  0.374
2010 Jensen ED, Gopalakrishnan R, Westendorf JJ. Regulation of gene expression in osteoblasts. Biofactors (Oxford, England). 36: 25-32. PMID 20087883 DOI: 10.1002/Biof.72  0.349
2010 Jensen ED, Pham L, Billington CJ, Espe K, Carlson AE, Westendorf JJ, Petryk A, Gopalakrishnan R, Mansky K. Bone morphogenic protein 2 directly enhances differentiation of murine osteoclast precursors. Journal of Cellular Biochemistry. 109: 672-82. PMID 20039313 DOI: 10.1002/Jcb.22462  0.472
2009 Li X, Hoeppner LH, Jensen ED, Gopalakrishnan R, Westendorf JJ. Co-activator activator (CoAA) prevents the transcriptional activity of Runt domain transcription factors. Journal of Cellular Biochemistry. 108: 378-87. PMID 19585539 DOI: 10.1002/Jcb.22263  0.383
2009 Sotillo Rodriguez JE, Mansky KC, Jensen ED, Carlson AE, Schwarz T, Pham L, MacKenzie B, Prasad H, Rohrer MD, Petryk A, Gopalakrishnan R. Enhanced osteoclastogenesis causes osteopenia in twisted gastrulation-deficient mice through increased BMP signaling. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 1917-26. PMID 19419314 DOI: 10.1359/Jbmr.090507  0.635
2009 MacKenzie B, Wolff R, Lowe N, Billington CJ, Peterson A, Schmidt B, Graf D, Mina M, Gopalakrishnan R, Petryk A. Twisted gastrulation limits apoptosis in the distal region of the mandibular arch in mice. Developmental Biology. 328: 13-23. PMID 19389368 DOI: 10.1016/J.Ydbio.2008.12.041  0.42
2009 Suttamanatwong S, Jensen ED, Schilling J, Franceschi RT, Carlson AE, Mansky KC, Gopalakrishnan R. Sp proteins and Runx2 mediate regulation of matrix gla protein (MGP) expression by parathyroid hormone. Journal of Cellular Biochemistry. 107: 284-92. PMID 19306294 DOI: 10.1002/Jcb.22124  0.751
2009 Jensen ED, Gopalakrishnan R, Westendorf JJ. Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2. The Journal of Biological Chemistry. 284: 2225-34. PMID 19029091 DOI: 10.1074/Jbc.M800586200  0.421
2009 Grigsby IF, Pham L, Mansky LM, Gopalakrishnan R, Mansky K. Tenofovir-associated bone density loss Therapeutics and Clinical Risk Management. 6: 41-47. DOI: 10.2147/Tcrm.S8836  0.403
2008 Jensen ED, Schroeder TM, Bailey J, Gopalakrishnan R, Westendorf JJ. Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 361-72. PMID 17997710 DOI: 10.1359/Jbmr.071104  0.345
2007 Suttamanatwong S, Franceschi RT, Carlson AE, Gopalakrishnan R. Regulation of matrix Gla protein by parathyroid hormone in MC3T3-E1 osteoblast-like cells involves protein kinase A and extracellular signal-regulated kinase pathways. Journal of Cellular Biochemistry. 102: 496-505. PMID 17407158 DOI: 10.1002/Jcb.21314  0.759
2006 Maes C, Coenegrachts L, Stockmans I, Daci E, Luttun A, Petryk A, Gopalakrishnan R, Moermans K, Smets N, Verfaillie CM, Carmeliet P, Bouillon R, Carmeliet G. Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair. The Journal of Clinical Investigation. 116: 1230-42. PMID 16614757 DOI: 10.1172/Jci26772  0.352
2005 Gopalakrishnan R, Suttamanatwong S, Carlson AE, Franceschi RT. Role of matrix Gla protein in parathyroid hormone inhibition of osteoblast mineralization. Cells, Tissues, Organs. 181: 166-75. PMID 16612082 DOI: 10.1159/000091378  0.768
2005 Roca H, Phimphilai M, Gopalakrishnan R, Xiao G, Franceschi RT. Cooperative interactions between RUNX2 and homeodomain protein-binding sites are critical for the osteoblast-specific expression of the bone sialoprotein gene. The Journal of Biological Chemistry. 280: 30845-55. PMID 16000302 DOI: 10.1074/Jbc.M503942200  0.353
2005 Petryk A, Shimmi O, Jia X, Carlson AE, Tervonen L, Jarcho MP, O'connor MB, Gopalakrishnan R. Twisted gastrulation and chordin inhibit differentiation and mineralization in MC3T3-E1 osteoblast-like cells. Bone. 36: 617-26. PMID 15780974 DOI: 10.1016/J.Bone.2005.01.018  0.465
2005 Hu JC-, Yamakoshi Y, Yamakoshi F, Krebsbach PH, Simmer JP, George A, Hao J, Young MF, Boskey AL, Kilts T, Verdelis K, Moradian-Oldak J, Goldberg M, Rawlins JT, McKee MD, ... ... Gopalakrishnan R, et al. Contents Vol. 181, 2005 Cells Tissues Organs. 181: 265-265. DOI: 10.1159/000092701  0.692
2005 Hu JC-, Yamakoshi Y, Yamakoshi F, Krebsbach PH, Simmer JP, George A, Hao J, Young MF, Boskey AL, Kilts T, Verdelis K, Moradian-Oldak J, Goldberg M, Rawlins JT, McKee MD, ... ... Gopalakrishnan R, et al. Subject Index Vol. 181, 2005 Cells Tissues Organs. 181: 264-264. DOI: 10.1159/000092700  0.688
2003 Gopalakrishnan R, Thomas PE, Benson MD, Wang D, Franceschi RT. A homeodomain protein binding element in the bone sialoprotein promoter is critical for tissue-specific expression in bone. Connective Tissue Research. 44: 154-60. PMID 12952190 DOI: 10.1080/03008200390152250  0.397
2003 Franceschi RT, Xiao G, Jiang D, Gopalakrishnan R, Yang S, Reith E. Multiple signaling pathways converge on the Cbfa1/Runx2 transcription factor to regulate osteoblast differentiation. Connective Tissue Research. 44: 109-16. PMID 12952183 DOI: 10.1080/03008200390152188  0.39
2002 Xiao G, Jiang D, Gopalakrishnan R, Franceschi RT. Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2. The Journal of Biological Chemistry. 277: 36181-7. PMID 12110689 DOI: 10.1074/Jbc.M206057200  0.456
2002 Xiao G, Gopalakrishnan R, Jiang D, Reith E, Benson MD, Franceschi RT. Bone morphogenetic proteins, extracellular matrix, and mitogen-activated protein kinase signaling pathways are required for osteoblast-specific gene expression and differentiation in MC3T3-E1 cells. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 101-10. PMID 11771655 DOI: 10.1359/Jbmr.2002.17.1.101  0.475
2001 Gopalakrishnan R, Ouyang H, Somerman MJ, McCauley LK, Franceschi RT. Matrix gamma-carboxyglutamic acid protein is a key regulator of PTH-mediated inhibition of mineralization in MC3T3-E1 osteoblast-like cells. Endocrinology. 142: 4379-88. PMID 11564701 DOI: 10.1210/Endo.142.10.8413  0.422
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