| Year |
Citation |
Score |
| 2023 |
Mack KL, Kim H, Barbieri EM, Lin J, Braganza S, Jackrel ME, DeNizio JE, Yan X, Chuang E, Tariq A, Cupo RR, Castellano LM, Caldwell KA, Caldwell GA, Shorter J. Tuning Hsp104 specificity to selectively detoxify α-synuclein. Molecular Cell. PMID 37625404 DOI: 10.1016/j.molcel.2023.07.029 |
0.732 |
|
| 2020 |
Zhu G, Harischandra DS, Ghaisas S, Zhang P, Prall W, Huang L, Maghames C, Guo L, Luna E, Mack KL, Torrente MP, Luk KC, Shorter J, Yang X. TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson's Disease. Cell Reports. 33: 108418. PMID 33264628 DOI: 10.1016/j.celrep.2020.108418 |
0.798 |
|
| 2020 |
Wobst HJ, Mack KL, Brown DG, Brandon NJ, Shorter J. The clinical trial landscape in amyotrophic lateral sclerosis-Past, present, and future. Medicinal Research Reviews. PMID 32043626 DOI: 10.1002/Med.21661 |
0.429 |
|
| 2019 |
Tariq A, Lin J, Jackrel ME, Hesketh CD, Carman PJ, Mack KL, Weitzman R, Gambogi C, Hernandez Murillo OA, Sweeny EA, Gurpinar E, Yokom AL, Gates SN, Yee K, Sudesh S, et al. Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity. Cell Reports. 28: 2080-2095.e6. PMID 31433984 DOI: 10.1016/J.Celrep.2019.07.069 |
0.782 |
|
| 2019 |
Durie CL, Lin J, Scull NW, Mack KL, Jackrel ME, Sweeny EA, Castellano LM, Shorter J, Lucius AL. Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. Biophysical Journal. PMID 31027887 DOI: 10.1016/J.Bpj.2019.03.035 |
0.78 |
|
| 2019 |
March ZM, Mack KL, Shorter J. AAA+ Protein-Based Technologies to Counter Neurodegenerative Disease. Biophysical Journal. PMID 30952364 DOI: 10.1016/J.Bpj.2019.03.007 |
0.792 |
|
| 2018 |
Tariq A, Lin J, Noll MM, Torrente MP, Mack KL, Murillo OH, Jackrel ME, Shorter J. Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain. Fems Yeast Research. 18. PMID 29788207 DOI: 10.1093/Femsyr/Foy042 |
0.778 |
|
| 2018 |
Weaver CL, Jackrel ME, Lin J, Mack KL, Sweeny E, Duran EC, Shorter J, Lucius AL. Kinetic Mechanism of ATP-Dependent Disaggregating Motor Saccharomyces cerevisiae Hsp104 Biophysical Journal. 114: 553a. DOI: 10.1016/J.Bpj.2017.11.3021 |
0.743 |
|
| 2017 |
Gates SN, Yokom AL, Lin J, Jackrel ME, Rizo AN, Kendsersky NM, Buell CE, Sweeny EA, Mack KL, Chuang E, Torrente MP, Su M, Shorter J, Southworth DR. Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Science (New York, N.Y.). PMID 28619716 DOI: 10.1126/Science.Aan1052 |
0.739 |
|
| 2017 |
Weaver CL, Duran EC, Mack KL, Lin J, Jackrel ME, Sweeny EA, Shorter J, Lucius AL. Avidity for polypeptide binding by nucleotide-bound Hsp104 structures. Biochemistry. PMID 28379007 DOI: 10.1021/Acs.Biochem.7B00225 |
0.768 |
|
| 2016 |
Yokom AL, Gates SN, Jackrel ME, Mack KL, Su M, Shorter J, Southworth DR. Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation. Nature Structural & Molecular Biology. PMID 27478928 DOI: 10.1038/Nsmb.3277 |
0.793 |
|
| 2016 |
Mack KL, Shorter J. Engineering and Evolution of Molecular Chaperones and Protein Disaggregases with Enhanced Activity. Frontiers in Molecular Biosciences. 3: 8. PMID 27014702 DOI: 10.3389/Fmolb.2016.00008 |
0.618 |
|
| 2015 |
Moroz YS, Dunston TT, Makhlynets OV, Moroz OV, Wu Y, Yoon JH, Olsen AB, McLaughlin JM, Mack KL, Gosavi PM, Van Nuland NA, Korendovych IV. New Tricks for Old Proteins: Single Mutations in a Non-enzymatic Protein Give Rise to Various Enzymatic Activities. Journal of the American Chemical Society. PMID 26555770 DOI: 10.1021/Jacs.5B07812 |
0.649 |
|
| 2015 |
Raymond EA, Mack KL, Yoon JH, Moroz OV, Moroz YS, Korendovych IV. Design of an allosterically regulated retroaldolase. Protein Science : a Publication of the Protein Society. 24: 561-70. PMID 25516403 DOI: 10.1002/Pro.2622 |
0.615 |
|
| 2013 |
Moroz OV, Moroz YS, Wu Y, Olsen AB, Cheng H, Mack KL, McLaughlin JM, Raymond EA, Zhezherya K, Roder H, Korendovych IV. A single mutation in a regulatory protein produces evolvable allosterically regulated catalyst of nonnatural reaction. Angewandte Chemie (International Ed. in English). 52: 6246-9. PMID 23630096 DOI: 10.1002/Anie.201302339 |
0.606 |
|
| 2013 |
Mack KL, Moroz OV, Moroz YS, Olsen AB, McLaughlin JM, Korendovych IV. Reprogramming EF-hands for design of catalytically amplified lanthanide sensors. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 18: 411-8. PMID 23420322 DOI: 10.1007/S00775-013-0985-5 |
0.567 |
|
| 2013 |
Mack KL, Moroz OV, Moroz YS, Olsen AB, McLaughlin JM, Korendovych IV. Erratum to: Reprogramming EF-hands for design of catalytically amplified lanthanide sensors Jbic Journal of Biological Inorganic Chemistry. 18: 591-591. DOI: 10.1007/S00775-013-1001-9 |
0.541 |
|
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