Lori A. Setton - Publications

Affiliations: 
Duke University, Durham, NC 
 Washington University, Saint Louis, St. Louis, MO 
Area:
Biomedical engineering, orthopaedic biomechanics, biomaterials
Website:
https://engineering.wustl.edu/faculty/Lori-Setton.html

182 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Basatvat S, Bach FC, Barcellona MN, Binch AL, Buckley CT, Bueno B, Chahine NO, Chee A, Creemers LB, Dudli S, Fearing B, Ferguson SJ, Gansau J, Gantenbein B, Gawri R, ... ... Setton L, et al. Harmonization and standardization of nucleus pulposus cell extraction and culture methods. Jor Spine. 6: e1238. PMID 36994456 DOI: 10.1002/jsp2.1238  0.793
2022 Rohanifar M, Clayton SW, Easson GWD, Patil DS, Lee F, Jing L, Barcellona MN, Speer JE, Stivers JJ, Tang SY, Setton LA. Single Cell RNA-Sequence Analyses Reveal Uniquely Expressed Genes and Heterogeneous Immune Cell Involvement in the Rat Model of Intervertebral Disc Degeneration. Applied Sciences (Basel, Switzerland). 12. PMID 36451894 DOI: 10.3390/app12168244  0.779
2022 Guang Y, Davis AL, McGrath TM, Pham CTN, Fitzpatrick JAJ, Setton LA. Correction to: Size-Dependent Effective Diffusivity in Healthy Human and Porcine Joint Synovium. Annals of Biomedical Engineering. PMID 35220481 DOI: 10.1007/s10439-022-02939-8  0.764
2022 Rohanifar M, Johnston BB, Davis AL, Guang Y, Nommensen K, Fitzpatrick JAJ, Pham CN, Setton LA. Hydraulic Permeability and Compressive Properties of Porcine and Human Synovium. Biophysical Journal. PMID 35032457 DOI: 10.1016/j.bpj.2022.01.008  0.769
2021 Guang Y, Cocciolone AJ, Crandall CL, Johnston BB, Setton LA, Wagenseil JE. A multiphasic model for determination of water and solute transport across the arterial wall: effects of elastic fiber defects. Archive of Applied Mechanics = Ingenieur-Archiv. 92: 447-459. PMID 35386426 DOI: 10.1007/s00419-021-01985-3  0.766
2021 Tan X, Jain E, Barcellona MN, Morris E, Neal S, Gupta MC, Buchowski JM, Kelly M, Setton LA, Huebsch N. Integrin and syndecan binding peptide-conjugated alginate hydrogel for modulation of nucleus pulposus cell phenotype. Biomaterials. 277: 121113. PMID 34492582 DOI: 10.1016/j.biomaterials.2021.121113  0.808
2021 Barcellona MN, Speer JE, Jing L, Patil DS, Gupta MC, Buchowski JM, Setton LA. Bioactive in situ crosslinkable polymer-peptide hydrogel for cell delivery to the intervertebral disc in a rat model. Acta Biomaterialia. PMID 34229105 DOI: 10.1016/j.actbio.2021.06.045  0.803
2021 Speer JE, Barcellona MN, Lu MY, Zha Z, Jing L, Gupta MC, Buchowski JM, Kelly MP, Setton LA. Development of a library of laminin-mimetic peptide hydrogels for control of nucleus pulposus cell behaviors. Journal of Tissue Engineering. 12: 20417314211021220. PMID 34188794 DOI: 10.1177/20417314211021220  0.804
2021 Klimak M, Nims RJ, Pferdehirt L, Collins KH, Harasymowicz NS, Oswald SJ, Setton LA, Guilak F. Immunoengineering the next generation of arthritis therapies. Acta Biomaterialia. PMID 33823324 DOI: 10.1016/j.actbio.2021.03.062  0.405
2021 Guang Y, Davis AL, McGrath TM, Pham CTN, Fitzpatrick JAJ, Setton LA. Size-Dependent Effective Diffusivity in Healthy Human and Porcine Joint Synovium. Annals of Biomedical Engineering. PMID 33495977 DOI: 10.1007/s10439-020-02717-4  0.786
2021 Berke IM, McGrath TM, Stivers JJ, Gui C, Barcellona MN, Gayoso MG, Tang SY, Cao YQ, Gupta MC, Setton LA. Electric Field Stimulation for the Functional Assessment of Isolated Dorsal Root Ganglion Neuron Excitability. Annals of Biomedical Engineering. PMID 33479787 DOI: 10.1007/s10439-021-02725-y  0.758
2020 Berke IM, Jain E, Yavuz B, McGrath T, Chen L, Silva MJ, Mbalaviele G, Guilak F, Kaplan DL, Setton LA. NF-κB-mediated effects on behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis. Osteoarthritis and Cartilage. PMID 33246158 DOI: 10.1016/j.joca.2020.10.008  0.775
2020 Barcellona MN, Speer JE, Fearing BV, Jing L, Pathak A, Gupta MC, Buchowski JM, Kelly M, Setton LA. Control of adhesive ligand density for modulation of nucleus pulposus cell phenotype. Biomaterials. 250: 120057. PMID 32361392 DOI: 10.1016/J.Biomaterials.2020.120057  0.791
2019 Fearing BV, Jing L, Barcellona MN, Witte SE, Buchowski JM, Zebala LP, Kelly MP, Luhmann S, Gupta MC, Pathak A, Setton LA. Mechanosensitive transcriptional coactivators MRTF-A and YAP/TAZ regulate nucleus pulposus cell phenotype through cell shape. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802725RRR. PMID 31638828 DOI: 10.1096/Fj.201802725Rrr  0.806
2019 Guang Y, McGrath TM, Klug N, Nims R, Shih CC, Bayguinov PO, Guilak F, Pham CTN, Fitzpatrick JAJ, Setton LA. Combined Experimental Approach and Finite Element Modeling of Small Molecule Transport Through Joint Synovium to Measure Effective Diffusivity. Journal of Biomechanical Engineering. PMID 31536113 DOI: 10.1115/1.4044892  0.774
2018 Fearing BV, Hernandez PA, Setton LA, Chahine NO. Mechanotransduction and cell biomechanics of the intervertebral disc. Jor Spine. 1. PMID 30569032 DOI: 10.1002/jsp2.1026  0.817
2018 Leimer EM, Tanenbaum LM, Nettles DL, Bell RD, Easley ME, Setton LA, Adams SB. Amino Acid Profile of Synovial Fluid Following Intra-articular Ankle Fracture. Foot & Ankle International. 1071100718786163. PMID 30111168 DOI: 10.1177/1071100718786163  0.763
2018 Mwangi TK, Berke I, Nieves EH, Bell RD, Adams SB, Setton LA. Intra-articular clearance of labeled dextrans from naive and arthritic rat knee joints. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29842918 DOI: 10.1016/J.Jconrel.2018.05.029  0.772
2018 Tang R, Jing L, Willard VP, Wu CL, Guilak F, Chen J, Setton LA. Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells. Stem Cell Research & Therapy. 9: 61. PMID 29523190 DOI: 10.1186/S13287-018-0797-1  0.524
2017 Bridgen DT, Fearing BV, Jing L, Sanchez-Adams J, Cohan MC, Guilak F, Chen J, Setton LA. Regulation of Human Nucleus Pulposus Cells by Peptide-Coupled Substrates. Acta Biomaterialia. PMID 28433788 DOI: 10.1016/J.Actbio.2017.04.019  0.799
2017 Bowles RD, Setton LA. Biomaterials for intervertebral disc regeneration and repair. Biomaterials. 129: 54-67. PMID 28324865 DOI: 10.1016/J.Biomaterials.2017.03.013  0.653
2017 Adams SB, Leimer EM, Setton LA, Bell RD, Easley ME, Huebner JL, Stabler TV, Kraus VB, Olson SA, Nettles DL. Inflammatory Microenvironment Persists After Bone Healing in Intra-articular Ankle Fractures. Foot & Ankle International. 1071100717690427. PMID 28142266 DOI: 10.1177/1071100717690427  0.718
2017 Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD. CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments. Tissue Engineering. Part A. PMID 28095751 DOI: 10.1089/Ten.Tea.2016.0441  0.792
2016 Hwang PY, Jing L, Chen J, Lim FL, Tang R, Choi H, Cheung KM, Risbud MV, Gersbach CA, Guilak F, Leung VY, Setton LA. N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions. Scientific Reports. 6: 28038. PMID 27292569 DOI: 10.1038/Srep28038  0.749
2016 Tang X, Jing L, Richardson WJ, Isaacs RE, Fitch RD, Brown CR, Erickson MM, Setton LA, Chen J. Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27018499 DOI: 10.1002/Jor.23244  0.749
2016 Leimer EM, Pappan KL, Nettles DL, Bell RD, Easley ME, Olson SA, Setton LA, Adams SB. Lipid profile of human synovial fluid following intra-articular ankle fracture. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 26924244 DOI: 10.1002/Jor.23217  0.72
2015 Adams SB, Setton LA, Bell RD, Easley ME, Huebner JL, Stabler T, Kraus VB, Leimer EM, Olson SA, Nettles DL. Inflammatory Cytokines and Matrix Metalloproteinases in the Synovial Fluid After Intra-articular Ankle Fracture. Foot & Ankle International. 36: 1264-71. PMID 26449389 DOI: 10.1177/1071100715611176  0.723
2015 Bowles RD, Karikari IO, VanDerwerken DN, Sinclair MS, Bell RD, Riebe KJ, Huebner JL, Kraus VB, Sempowski GD, Setton LA. In vivo luminescent imaging of NF-κB activity and NF-κB-related serum cytokine levels predict pain sensitivities in a rodent model of peripheral neuropathy. European Journal of Pain (London, England). PMID 26032161 DOI: 10.1002/Ejp.732  0.72
2015 Hwang PY, Jing L, Michael KW, Richardson WJ, Chen J, Setton LA. N-Cadherin-Mediated Signaling Regulates Cell Phenotype for Nucleus Pulposus Cells of the Intervertebral Disc. Cellular and Molecular Bioengineering. 8: 51-62. PMID 25848407 DOI: 10.1007/S12195-014-0373-4  0.698
2015 Mwangi TK, Bowles RD, Tainter DM, Bell RD, Kaplan DL, Setton LA. Synthesis and characterization of silk fibroin microparticles for intra-articular drug delivery. International Journal of Pharmaceutics. 485: 7-14. PMID 25724134 DOI: 10.1016/J.Ijpharm.2015.02.059  0.772
2015 Kimmerling KA, Furman BD, Mangiapani DS, Moverman MA, Sinclair SM, Huebner JL, Chilkoti A, Kraus VB, Setton LA, Guilak F, Olson SA. Sustained intra-articular delivery of IL-1RA from a thermally-responsive elastin-like polypeptide as a therapy for post-traumatic arthritis. European Cells & Materials. 29: 124-39; discussion 1. PMID 25636786 DOI: 10.22203/Ecm.V029A10  0.77
2015 Cucchiarini M, McNulty AL, Mauck RL, Setton LA, Guilak F, Madry H. Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus Osteoarthritis and Cartilage. DOI: 10.1016/j.joca.2016.03.018  0.429
2014 Karikari IO, Gilchrist CL, Jing L, Alcorta DA, Chen J, Richardson WJ, Gabr MA, Bell RD, Kelley MJ, Bagley CA, Setton LA. Molecular characterization of chordoma xenografts generated from a novel primary chordoma cell source and two chordoma cell lines. Journal of Neurosurgery. Spine. 21: 386-93. PMID 24905390 DOI: 10.3171/2014.4.Spine13262  0.779
2014 Jeong CG, Francisco AT, Niu Z, Mancino RL, Craig SL, Setton LA. Screening of hyaluronic acid-poly(ethylene glycol) composite hydrogels to support intervertebral disc cell biosynthesis using artificial neural network analysis. Acta Biomaterialia. 10: 3421-30. PMID 24859415 DOI: 10.1016/J.Actbio.2014.05.012  0.802
2014 Bowles RD, Mata BA, Bell RD, Mwangi TK, Huebner JL, Kraus VB, Setton LA. In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). 66: 637-46. PMID 24574224 DOI: 10.1002/Art.38279  0.768
2014 Hwang PY, Chen J, Jing L, Hoffman BD, Setton LA. The role of extracellular matrix elasticity and composition in regulating the nucleus pulposus cell phenotype in the intervertebral disc: a narrative review. Journal of Biomechanical Engineering. 136: 021010. PMID 24390195 DOI: 10.1115/1.4026360  0.71
2014 Francisco AT, Hwang PY, Jeong CG, Jing L, Chen J, Setton LA. Photocrosslinkable laminin-functionalized polyethylene glycol hydrogel for intervertebral disc regeneration. Acta Biomaterialia. 10: 1102-11. PMID 24287160 DOI: 10.1016/J.Actbio.2013.11.013  0.809
2014 Setton LA, Kraus VB, Bowles RD. In Vivo Imaging of NF-κB Activity, Pain Sensitivity, and Serum Cytokines in a Rodent Model of Neuropathy Global Spine Journal. 4: s-0034-1376757-s-003. DOI: 10.1055/S-0034-1376757  0.637
2014 Tang X, Jing L, Setton LA, Richardson WJ, Fitch RD, Isaacs RE, Brown CR, Michael KW, Chen J. Cell Phenotype and Matrix Regeneration of Human Nucleus Pulposus Cells of Different Ages in a Laminin-Rich Pseudo-3D Culture System in Vitro Global Spine Journal. 4: s-0034-1376648-s-003. DOI: 10.1055/S-0034-1376648  0.314
2014 Hwang PY, Jing L, Richardson WJ, Isaacs RE, Michael KW, Chen J, Setton LA. N-Cadherin-Mediated Cell Signaling in Nucleus Pulposus Cells of the Intervertebral Disc Global Spine Journal. 4: s-0034-1376616-s-003. DOI: 10.1055/S-0034-1376616  0.672
2014 Jing L, Francisco AT, Chakraborty S, Leong KW, Setton LA, Chen J. Differentiation of Human-Induced Pluripotent Stem Cells (iPSCs) on Laminin-functionalized PEG Hydrogels under Nucleus Pulposus-Like Culture Conditions Global Spine Journal. 4: s-0034-1376571-s-003. DOI: 10.1055/S-0034-1376571  0.798
2014 Winkelstein BA, Allen KD, Setton LA. Intervertebral disc herniation: Pathophysiology and emerging therapies The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease. 305-326. DOI: 10.1007/978-3-7091-1535-0_19  0.52
2013 Chon BH, Lee EJ, Jing L, Setton LA, Chen J. Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system. Stem Cell Research & Therapy. 4: 120. PMID 24405888 DOI: 10.1186/Scrt331  0.361
2013 Chen J, Lee EJ, Jing L, Christoforou N, Leong KW, Setton LA. Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro. Plos One. 8: e75548. PMID 24086564 DOI: 10.1371/Journal.Pone.0075548  0.352
2013 Francisco AT, Mancino RJ, Bowles RD, Brunger JM, Tainter DM, Chen YT, Richardson WJ, Guilak F, Setton LA. Injectable laminin-functionalized hydrogel for nucleus pulposus regeneration. Biomaterials. 34: 7381-8. PMID 23849345 DOI: 10.1016/J.Biomaterials.2013.06.038  0.816
2013 Sinclair SM, Bhattacharyya J, McDaniel JR, Gooden DM, Gopalaswamy R, Chilkoti A, Setton LA. A genetically engineered thermally responsive sustained release curcumin depot to treat neuroinflammation. Journal of Controlled Release : Official Journal of the Controlled Release Society. 171: 38-47. PMID 23830979 DOI: 10.1016/J.Jconrel.2013.06.032  0.748
2013 Bridgen DT, Gilchrist CL, Richardson WJ, Isaacs RE, Brown CR, Yang KL, Chen J, Setton LA. Integrin-mediated interactions with extracellular matrix proteins for nucleus pulposus cells of the human intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 1661-7. PMID 23737292 DOI: 10.1002/Jor.22395  0.809
2013 Adams SB, Setton LA, Nettles DL. The role of metabolomics in osteoarthritis research. The Journal of the American Academy of Orthopaedic Surgeons. 21: 63-4. PMID 23281473 DOI: 10.5435/Jaaos-21-01-63  0.727
2013 Mata BA, Bowles R, Mwangi TK, Setton LA. Impaired Function and in vivo Imaging of NF-κB Activation in a Mouse Model of Knee Joint Inflammation The Duke Orthopaedic Journal. 3: 41-47. DOI: 10.5005/JP-JOURNALS-10017-1028  0.653
2013 Karikari IO, Bowles R, Setton L. Correlation of Pain Response and In Vivo Imaging of NF-кB Activity in a Model of Radiculopathy The Spine Journal. 13: S54-S55. DOI: 10.1016/J.Spinee.2013.07.158  0.737
2013 Sinclair S, Bhattacharyya J, Little D, Bowles R, Gooden D, Toone E, Chilkoti A, Setton L. Pharmacokinetics of a thermally responsive curcumin conjugate for local antagonism of neuroinflammation in disc herniation Osteoarthritis and Cartilage. 21: S292-S293. DOI: 10.1016/J.Joca.2013.02.613  0.762
2013 Francisco A, Mancino R, Brunger J, Bowles R, Guilak F, Setton L. Injectable laminin-functionalized hydrogel for cell delivery to the intervertebral disc Osteoarthritis and Cartilage. 21: S278-S279. DOI: 10.1016/J.Joca.2013.02.585  0.798
2013 Bowles R, Mata B, Mwangi T, Palmer G, Setton L. In vivo imaging of NF-кB activity and correlation to pain in a model of inflammatory arthritis Osteoarthritis and Cartilage. 21: S266-S267. DOI: 10.1016/J.Joca.2013.02.557  0.766
2013 Tainter D, Bell R, Nettles D, Setton L, Parekh S, Adams S. Glutamate is elevated in pathologic posterior tibial tendons of patients with posterior tibial tendon dysfunction Osteoarthritis and Cartilage. 21: S261. DOI: 10.1016/J.Joca.2013.02.543  0.712
2013 Bowles R, Karikari I, Riebe K, Sempowski G, Setton L. In vivo imaging of NF-кB activity and correlation to pain in a model of radiculopathy Osteoarthritis and Cartilage. 21: S59-S60. DOI: 10.1016/J.Joca.2013.02.133  0.719
2013 Kimmerling K, Furman B, Mangiapani D, Moverman M, Sinclair S, Huebner J, Kraus V, Setton L, Guilak F, Olson S. Prolonged local delivery of IL-1Ra prevents post-traumatic arthritis in mice Osteoarthritis and Cartilage. 21: S30-S31. DOI: 10.1016/J.Joca.2013.02.082  0.791
2012 Hwang PY, Allen KD, Shamji MF, Jing L, Mata BA, Gabr MA, Huebner JL, Kraus VB, Richardson WJ, Setton LA. Changes in midbrain pain receptor expression, gait and behavioral sensitivity in a rat model of radiculopathy. The Open Orthopaedics Journal. 6: 383-91. PMID 22962568 DOI: 10.2174/1874325001206010383  0.785
2012 Jing L, So S, Lim SW, Richardson WJ, Fitch RD, Setton LA, Chen J. Differential expression of galectin-1 and its interactions with cells and laminins in the intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1923-31. PMID 22692729 DOI: 10.1002/Jor.22158  0.369
2012 Allen KD, Mata BA, Gabr MA, Huebner JL, Adams SB, Kraus VB, Schmitt DO, Setton LA. Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis. Arthritis Research & Therapy. 14: R78. PMID 22510443 DOI: 10.1186/Ar3801  0.785
2012 Adams SB, Setton LA, Kensicki E, Bolognesi MP, Toth AP, Nettles DL. Global metabolic profiling of human osteoarthritic synovium. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 20: 64-7. PMID 22063369 DOI: 10.1016/J.Joca.2011.10.010  0.727
2012 Francisco AT, Mancino RJ, Jeong CG, Karikari IO, Bowles RD, Craig SL, Setton LA. Injectable and photocrosslinkable laminin functionalized biomaterials for intervertebral disc regeneration Asme 2012 Summer Bioengineering Conference, Sbc 2012. 1145-1146. DOI: 10.1115/SBC2012-80660  0.767
2012 Hwang PY, Gilchrist CL, Francisco AT, Chen J, Setton LA. Cell morphology and migration of nucleus pulposus cells depends on substrate stiffness and ligand Asme 2012 Summer Bioengineering Conference, Sbc 2012. 1205-1206. DOI: 10.1115/SBC2012-80338  0.817
2011 Gilchrist CL, Darling EM, Chen J, Setton LA. Extracellular matrix ligand and stiffness modulate immature nucleus pulposus cell-cell interactions. Plos One. 6: e27170. PMID 22087260 DOI: 10.1371/Journal.Pone.0027170  0.788
2011 Allen KD, Shamji MF, Mata BA, Gabr MA, Sinclair SM, Schmitt DO, Richardson WJ, Setton LA. Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonism. Arthritis Research & Therapy. 13: R137. PMID 21871102 DOI: 10.1186/Ar3451  0.787
2011 Gilchrist CL, Francisco AT, Plopper GE, Chen J, Setton LA. Nucleus pulposus cell-matrix interactions with laminins. European Cells & Materials. 21: 523-32. PMID 21710443  0.812
2011 Allen KD, Adams SB, Mata BA, Shamji MF, Gouze E, Jing L, Nettles DL, Latt LD, Setton LA. Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 694-703. PMID 21437948 DOI: 10.1002/Jor.21309  0.79
2011 Sinclair SM, Shamji MF, Chen J, Jing L, Richardson WJ, Brown CR, Fitch RD, Setton LA. Attenuation of inflammatory events in human intervertebral disc cells with a tumor necrosis factor antagonist. Spine. 36: 1190-6. PMID 21217452 DOI: 10.1016/S1063-4584(09)60554-9  0.799
2011 Gabr MA, Jing L, Helbling AR, Sinclair SM, Allen KD, Shamji MF, Richardson WJ, Fitch RD, Setton LA, Chen J. Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 1-7. PMID 20665551 DOI: 10.1002/Jor.21206  0.784
2011 Cao L, Guilak F, Setton LA. Three-dimensional finite element modeling of pericellular matrix and cell mechanics in the nucleus pulposus of the intervertebral disk based on in situ morphology. Biomechanics and Modeling in Mechanobiology. 10: 1-10. PMID 20376522 DOI: 10.1007/S10237-010-0214-X  0.595
2011 Allen K, Mata B, Gabr M, Huebner J, Kraus V, Setton L. 177 GAIT COMPENSATIONS IN A RAT MEDIAL MENISCUS TRANSECTION MODEL OF OSTEOARTHRITIS Osteoarthritis and Cartilage. 19: S88-S89. DOI: 10.1016/S1063-4584(11)60204-5  0.704
2010 Griffin TM, Fermor B, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Cao L, Setton LA, Guilak F. Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. Arthritis Research & Therapy. 12: R130. PMID 20604941 DOI: 10.1186/Ar3068  0.513
2010 Nettles DL, Chilkoti A, Setton LA. Applications of elastin-like polypeptides in tissue engineering. Advanced Drug Delivery Reviews. 62: 1479-85. PMID 20385185 DOI: 10.1016/J.Addr.2010.04.002  0.679
2010 Costello KE, Guilak F, Setton LA, Griffin TM. Locomotor activity and gait in aged mice deficient for type IX collagen. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 211-8. PMID 20360435 DOI: 10.1152/Japplphysiol.00056.2010  0.397
2010 Shamji MF, Setton LA, Jarvis W, So S, Chen J, Jing L, Bullock R, Isaacs RE, Brown C, Richardson WJ. Proinflammatory cytokine expression profile in degenerated and herniated human intervertebral disc tissues. Arthritis and Rheumatism. 62: 1974-82. PMID 20222111 DOI: 10.1002/Art.27444  0.585
2010 Allen KD, Adams SB, Setton LA. Evaluating intra-articular drug delivery for the treatment of osteoarthritis in a rat model. Tissue Engineering. Part B, Reviews. 16: 81-92. PMID 19943805 DOI: 10.1089/Ten.Teb.2009.0447  0.667
2010 Nettles DL, Haider MA, Chilkoti A, Setton LA. Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds. Tissue Engineering. Part A. 16: 11-20. PMID 19754250 DOI: 10.1089/Ten.Tea.2009.0134  0.784
2009 Cao L, Guilak F, Setton LA. Pericellular Matrix Mechanics in the Anulus Fibrosus Predicted by a Three-Dimensional Finite Element Model and In Situ Morphology. Cellular and Molecular Bioengineering. 2: 306-319. PMID 19946619 DOI: 10.1007/S12195-009-0081-7  0.576
2009 Chen J, Jing L, Gilchrist CL, Richardson WJ, Fitch RD, Setton LA. Expression of laminin isoforms, receptors, and binding proteins unique to nucleus pulposus cells of immature intervertebral disc. Connective Tissue Research. 50: 294-306. PMID 19863388 DOI: 10.3109/03008200802714925  0.768
2009 Mow VC, Michael Lai W, Setton LA, Gu W, Yao H, Wan LQ, Lu XL. Discussion: "On the Thermodynamical Admissibility of the Triphasic Theory of Charged Hydrated Tissues" (Huyghe, J. M., Wilson, W., and Malakpoor, K., ASME J. Biomech. Eng., 2009, 131, p. 044504). Journal of Biomechanical Engineering. 131: 095501. PMID 19725705 DOI: 10.1115/1.3128727  0.749
2009 Allen KD, Griffin TM, Rodriguiz RM, Wetsel WC, Kraus VB, Huebner JL, Boyd LM, Setton LA. Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. Arthritis and Rheumatism. 60: 2684-93. PMID 19714629 DOI: 10.1002/Art.24783  0.732
2009 Christensen T, Amiram M, Dagher S, Trabbic-Carlson K, Shamji MF, Setton LA, Chilkoti A. Fusion order controls expression level and activity of elastin-like polypeptide fusion proteins. Protein Science : a Publication of the Protein Society. 18: 1377-87. PMID 19533768 DOI: 10.1002/Pro.157  0.502
2009 Shamji MF, Allen KD, So S, Jing L, Adams SB, Schuh R, Huebner J, Kraus VB, Friedman AH, Setton LA, Richardson WJ. Gait abnormalities and inflammatory cytokines in an autologous nucleus pulposus model of radiculopathy. Spine. 34: 648-54. PMID 19333095 DOI: 10.1097/Brs.0B013E318197F013  0.761
2009 Nettles DL, Chilkoti A, Setton LA. Early metabolite levels predict long-term matrix accumulation for chondrocytes in elastin-like polypeptide biopolymer scaffolds. Tissue Engineering. Part A. 15: 2113-21. PMID 19193139 DOI: 10.1089/Ten.Tea.2008.0448  0.701
2009 Shamji MF, Hwang P, Bullock RW, Adams SB, Nettles DL, Setton LA. Release and activity of anti-TNFalpha therapeutics from injectable chitosan preparations for local drug delivery. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 90: 319-26. PMID 19072988 DOI: 10.1002/Jbm.B.31289  0.779
2009 Adams SB, Shamji MF, Nettles DL, Hwang P, Setton LA. Sustained release of antibiotics from injectable and thermally responsive polypeptide depots. Journal of Biomedical Materials Research. Part B, Applied Biomaterials. 90: 67-74. PMID 18988275 DOI: 10.1002/Jbm.B.31254  0.775
2009 Gabr M, Setton L, Sinclair S, Jing L, Brown C, Richardson W, Chen J. 498 A T-CELL ASSOCIATED CYTOKINE, INTERLEUKIN-17, PROMOTES AN INFLAMMATORY PHENOTYPE IN DEGENERATIVE HUMAN INTERVERTEBRAL DISC CELLS Osteoarthritis and Cartilage. 17: S268. DOI: 10.1016/S1063-4584(09)60519-7  0.792
2009 Allen K, Adams S, Latt D, Nettles D, Setton L. 496 A SINGLE INTRA-ARTICULAR INJECTION OF INTERLEUKIN 1 RECEPTOR ANTAGONIST IS INSUFFICIENT TO RESTORE GAIT DEFICIENCY RESULTING FROM INTERLEUKIN-1 MEDIATED CARTILAGE DESTRUCTION IN A RODENT MODEL Osteoarthritis and Cartilage. 17: S266-S267. DOI: 10.1016/S1063-4584(09)60517-3  0.783
2008 Shamji MF, Jing L, Chen J, Hwang P, Ghodsizadeh O, Friedman AH, Richardson WJ, Setton LA. Treatment of neuroinflammation by soluble tumor necrosis factor receptor Type II fused to a thermally responsive carrier. Journal of Neurosurgery. Spine. 9: 221-8. PMID 18764758 DOI: 10.3171/Spi/2008/9/8/221  0.75
2008 Shamji MF, Chen J, Friedman AH, Richardson WJ, Chilkoti A, Setton LA. Synthesis and characterization of a thermally-responsive tumor necrosis factor antagonist. Journal of Controlled Release : Official Journal of the Controlled Release Society. 129: 179-86. PMID 18547669 DOI: 10.1016/J.Jconrel.2008.04.021  0.579
2008 Upton ML, Gilchrist CL, Guilak F, Setton LA. Transfer of macroscale tissue strain to microscale cell regions in the deformed meniscus. Biophysical Journal. 95: 2116-24. PMID 18487290 DOI: 10.1529/Biophysj.107.126938  0.785
2008 Nettles DL, Kitaoka K, Hanson NA, Flahiff CM, Mata BA, Hsu EW, Chilkoti A, Setton LA. In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model. Tissue Engineering. Part A. 14: 1133-40. PMID 18433311 DOI: 10.1089/Ten.Tea.2007.0245  0.793
2008 Shamji MF, Whitlatch L, Friedman AH, Richardson WJ, Chilkoti A, Setton LA. An injectable and in situ-gelling biopolymer for sustained drug release following perineural administration. Spine. 33: 748-54. PMID 18379401 DOI: 10.1097/Brs.0B013E3181695773  0.555
2008 Lim DW, Nettles DL, Setton LA, Chilkoti A. In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair. Biomacromolecules. 9: 222-30. PMID 18163573 DOI: 10.1021/Bm7007982  0.686
2008 Boyd LM, Richardson WJ, Allen KD, Flahiff C, Jing L, Li Y, Chen J, Setton LA. Early-onset degeneration of the intervertebral disc and vertebral end plate in mice deficient in type IX collagen. Arthritis and Rheumatism. 58: 164-71. PMID 18163498 DOI: 10.1002/Art.23231  0.759
2008 Shamji MF, Allen KD, Adams SB, So S, Jing L, Chen J, Richardson WJ, Setton LA. GAIT ABNORMALITIES AND SENSORY CHANGES ACCOMPANY NEURO-INFLAMMATION IN ANIMAL MODELS OF DISC HERNIATION RADICULOPATHY Clinical & Investigative Medicine. 31: 21. DOI: 10.25011/Cim.V31I4.4825  0.766
2007 Shamji MF, Betre H, Kraus VB, Chen J, Chilkoti A, Pichika R, Masuda K, Setton LA. Development and characterization of a fusion protein between thermally responsive elastin-like polypeptide and interleukin-1 receptor antagonist: sustained release of a local antiinflammatory therapeutic. Arthritis and Rheumatism. 56: 3650-61. PMID 17968946 DOI: 10.1002/Art.22952  0.778
2007 Cao L, Guilak F, Setton LA. Three-dimensional morphology of the pericellular matrix of intervertebral disc cells in the rat. Journal of Anatomy. 211: 444-52. PMID 17672847 DOI: 10.1111/J.1469-7580.2007.00784.X  0.566
2007 Roberts SK, Chilkoti A, Setton LA. Multifunctional thermally transitioning oligopeptides prepared by ring-opening metathesis polymerization. Biomacromolecules. 8: 2618-21. PMID 17625908 DOI: 10.1021/bm0702713  0.49
2007 Lim DW, Nettles DL, Setton LA, Chilkoti A. Rapid cross-linking of elastin-like polypeptides with (hydroxymethyl)phosphines in aqueous solution. Biomacromolecules. 8: 1463-70. PMID 17411091 DOI: 10.1021/Bm061059M  0.675
2007 Choi JB, Youn I, Cao L, Leddy HA, Gilchrist CL, Setton LA, Guilak F. Zonal changes in the three-dimensional morphology of the chondron under compression: the relationship among cellular, pericellular, and extracellular deformation in articular cartilage. Journal of Biomechanics. 40: 2596-603. PMID 17397851 DOI: 10.1016/J.Jbiomech.2007.01.009  0.794
2007 Gilchrist CL, Chen J, Richardson WJ, Loeser RF, Setton LA. Functional integrin subunits regulating cell-matrix interactions in the intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 25: 829-40. PMID 17318895 DOI: 10.1002/Jor.20343  0.776
2007 Gilchrist CL, Witvoet-Braam SW, Guilak F, Setton LA. Measurement of intracellular strain on deformable substrates with texture correlation. Journal of Biomechanics. 40: 786-94. PMID 16698026 DOI: 10.1016/J.Jbiomech.2006.03.013  0.769
2007 Shamji MF, Ghodsizadeh O, Friedman AH, Richardson WJ, Chilkoti A, Setton LA. Development of a thermally responsive peptide for sustained deliver of solyble TNF receptor II to attenuate inflammatory events associated with radiculopathys Clinical & Investigative Medicine. 30: 94. DOI: 10.25011/Cim.V30I4.2873  0.561
2007 Shamji M, Betre H, Chen J, Kraus V, Chilkoti A, Setton L. 418 DEVELOPMENT OF A THERMALLY RESPONSIVE DRUG DEPOT FOR INTRA-ARTICULAR DELIVERY OF INTERLEUKIN-1 RECEPTOR ANTAGONIST TO ATTENUATE INFLAMMATORY EVENTS IN OSTEOARTHRITIS Osteoarthritis and Cartilage. 15: C226-C227. DOI: 10.1016/S1063-4584(07)62049-4  0.772
2007 Adams S, Shamji M, Nettles D, Paranjape S, Evans C, Gouze E, Setton L. 413 INTRA-ARTICULAR DELIVERY OF INTERLEUKIN-1 RECEPTOR ANTAGONIST FUSED TO A THERMALLY RESPONSIVE PEPTIDE IS EFFECTIVE IN MODULATING THE PATHOLOGIC RESPONSE TO INTERLEUKIN-1 INDUCED KNEE JOINT DESTRUCTION Osteoarthritis and Cartilage. 15: C224. DOI: 10.1016/S1063-4584(07)62044-5  0.784
2007 Chen J, Boyd L, Allen K, Tsuboyama M, Jing L, Malfait A, Setton L. 31 EVALUATION OF INTERVERTEBRAL DISC AND VERTEBRAL ENDPLATE DEGENERATION IN ADAMTS5 (AGGRECANASE-2) KNOCKOUT MICE Osteoarthritis and Cartilage. 15: C31-C32. DOI: 10.1016/S1063-4584(07)61667-7  0.721
2007 Allen K, Griffin T, Wetsel W, Rodriguiz R, Boyd L, Setton L. 3 TYPE IX COLLAGEN KNOCKOUT IS ASSOCIATED WITH ALTERED GAIT BEHAVIORS AND MECHANICAL ALLODYNIA IN MICE Osteoarthritis and Cartilage. 15: C16. DOI: 10.1016/S1063-4584(07)61639-2  0.727
2007 Chen J, Jing L, Gilchrist C, Richardson W, Fitch R, Setton L. P137 Expression of laminin binding receptors is a unique feature of immature nucleus pulposus cells Osteoarthritis and Cartilage. 15: B122. DOI: 10.1016/S1063-4584(07)61492-7  0.735
2007 Nettles D, Chilkoti A, Setton L. P124 Metabolites in Culture Media Predict Cartilage Extracellular Matrix Accumulation For Chondrocytes in Crosslinked Polypeptide Gels Osteoarthritis and Cartilage. 15: B119. DOI: 10.1016/S1063-4584(07)61479-4  0.702
2007 Setton L, Nettles D, Lim D, Guilak F, Chilkoti A. 4.1 Genetically engineered elastin-like polypeptides for cartilage tissue regeneration Osteoarthritis and Cartilage. 15: B2-B5. DOI: 10.1016/S1063-4584(07)61225-4  0.718
2006 Cao L, Youn I, Guilak F, Setton LA. Compressive properties of mouse articular cartilage determined in a novel micro-indentation test method and biphasic finite element model. Journal of Biomechanical Engineering. 128: 766-71. PMID 16995764 DOI: 10.1115/1.2246237  0.542
2006 Upton ML, Hennerbichler A, Fermor B, Guilak F, Weinberg JB, Setton LA. Biaxial strain effects on cells from the inner and outer regions of the meniscus. Connective Tissue Research. 47: 207-14. PMID 16987752 DOI: 10.1080/03008200600846663  0.812
2006 Betre H, Liu W, Zalutsky MR, Chilkoti A, Kraus VB, Setton LA. A thermally responsive biopolymer for intra-articular drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 115: 175-82. PMID 16959360 DOI: 10.1016/J.Jconrel.2006.07.022  0.783
2006 Hu K, Xu L, Cao L, Flahiff CM, Brussiau J, Ho K, Setton LA, Youn I, Guilak F, Olsen BR, Li Y. Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen Arthritis and Rheumatism. 54: 2891-2900. PMID 16947423 DOI: 10.1002/Art.22040  0.536
2006 Guilak F, Alexopoulos LG, Upton ML, Youn I, Choi JB, Cao L, Setton LA, Haider MA. The pericellular matrix as a transducer of biomechanical and biochemical signals in articular cartilage. Annals of the New York Academy of Sciences. 1068: 498-512. PMID 16831947 DOI: 10.1196/Annals.1346.011  0.809
2006 Upton ML, Chen J, Setton LA. Region-specific constitutive gene expression in the adult porcine meniscus. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 1562-70. PMID 16732608 DOI: 10.1002/Jor.20146  0.782
2006 Youn I, Choi JB, Cao L, Setton LA, Guilak F. Zonal variations in the three-dimensional morphology of the chondron measured in situ using confocal microscopy Osteoarthritis and Cartilage. 14: 889-897. PMID 16626979 DOI: 10.1016/J.Joca.2006.02.017  0.575
2006 Setton LA, Chen J. Mechanobiology of the intervertebral disc and relevance to disc degeneration. The Journal of Bone and Joint Surgery. American Volume. 88: 52-7. PMID 16595444 DOI: 10.2106/Jbjs.F.00001  0.342
2006 Chen J, Yan W, Setton LA. Molecular phenotypes of notochordal cells purified from immature nucleus pulposus. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 15: S303-11. PMID 16547755 DOI: 10.1007/S00586-006-0088-X  0.362
2006 Haider MA, Schugart RC, Setton LA, Guilak F. A mechano-chemical model for the passive swelling response of an isolated chondron under osmotic loading. Biomechanics and Modeling in Mechanobiology. 5: 160-71. PMID 16520959 DOI: 10.1007/S10237-006-0026-1  0.793
2006 Upton ML, Guilak F, Laursen TA, Setton LA. Finite element modeling predictions of region-specific cell-matrix mechanics in the meniscus. Biomechanics and Modeling in Mechanobiology. 5: 140-9. PMID 16520958 DOI: 10.1007/S10237-006-0031-4  0.811
2006 Söntjens SH, Nettles DL, Carnahan MA, Setton LA, Grinstaff MW. Biodendrimer-based hydrogel scaffolds for cartilage tissue repair. Biomacromolecules. 7: 310-6. PMID 16398530 DOI: 10.1021/Bm050663E  0.695
2006 Ong SR, Trabbic-Carlson KA, Nettles DL, Lim DW, Chilkoti A, Setton LA. Epitope tagging for tracking elastin-like polypeptides. Biomaterials. 27: 1930-5. PMID 16278015 DOI: 10.1016/J.Biomaterials.2005.10.018  0.695
2006 Hyun J, Chen J, Setton LA, Chilkoti A. Patterning cells in highly deformable microstructures: effect of plastic deformation of substrate on cellular phenotype and gene expression. Biomaterials. 27: 1444-51. PMID 16154191 DOI: 10.1016/J.Biomaterials.2005.08.018  0.322
2006 Betre H, Ong SR, Guilak F, Chilkoti A, Fermor B, Setton LA. Chondrocytic differentiation of human adipose-derived adult stem cells in elastin-like polypeptide. Biomaterials. 27: 91-9. PMID 16023192 DOI: 10.1016/J.Biomaterials.2005.05.071  0.79
2006 Upton M, Guilak F, Laursen T, Setton L. Biphasic finite element predictions for region-specific meniscus cell-matrix mechanics Journal of Biomechanics. 39: S407. DOI: 10.1016/S0021-9290(06)84651-8  0.782
2006 Gilchrist G, Witvoet-Braam S, Guilak F, Setton L. Intracellular measurements of strain transfer using texture correlation Journal of Biomechanics. 39: S228-S229. DOI: 10.1016/S0021-9290(06)83846-7  0.344
2006 Boyd L, Clapp M, Richardson W, Odom D, Jing L, Chen J, Setton L. Static compression modulates gene expression in the murine intervertebral disc in vitro Journal of Biomechanics. 39: S27. DOI: 10.1016/S0021-9290(06)82976-3  0.647
2006 Cao L, Youn I, Flahiff C, Li Y, Guilak F, Olsen B, Setton L. Altered cartilage mechanics in knee joints of type IX collagen deficient mice Journal of Biomechanics. 39: S23. DOI: 10.1016/S0021-9290(06)82959-3  0.519
2005 Alexopoulos LG, Setton LA, Guilak F. The biomechanical role of the chondrocyte pericellular matrix in articular cartilage. Acta Biomaterialia. 1: 317-25. PMID 16701810 DOI: 10.1016/J.Actbio.2005.02.001  0.494
2005 Guilak F, Alexopoulos LG, Haider MA, Ting-Beall HP, Setton LA. Zonal uniformity in mechanical properties of the chondrocyte pericellular matrix: micropipette aspiration of canine chondrons isolated by cartilage homogenization. Annals of Biomedical Engineering. 33: 1312-8. PMID 16240080 DOI: 10.1007/S10439-005-4479-7  0.736
2005 Boyd LM, Richardson WJ, Chen J, Kraus VB, Tewari A, Setton LA. Osmolarity regulates gene expression in intervertebral disc cells determined by gene array and real-time quantitative RT-PCR. Annals of Biomedical Engineering. 33: 1071-7. PMID 16133915 DOI: 10.1007/S10439-005-5775-Y  0.675
2005 Alexopoulos LG, Williams GM, Upton ML, Setton LA, Guilak F. Osteoarthritic changes in the biphasic mechanical properties of the chondrocyte pericellular matrix in articular cartilage. Journal of Biomechanics. 38: 509-17. PMID 15652549 DOI: 10.1016/J.Jbiomech.2004.04.012  0.806
2004 Setton LA, Chen J. Cell mechanics and mechanobiology in the intervertebral disc. Spine. 29: 2710-23. PMID 15564920 DOI: 10.1097/01.Brs.0000146050.57722.2A  0.35
2004 An HS, Anderson PA, Haughton VM, Iatridis JC, Kang JD, Lotz JC, Natarajan RN, Oegema TR, Roughley P, Setton LA, Urban JP, Videman T, Andersson GB, Weinstein JN. Introduction: disc degeneration: summary. Spine. 29: 2677-8. PMID 15564916 DOI: 10.1097/01.Brs.0000147573.88916.C6  0.464
2004 Boyd LM, Chen J, Kraus VB, Setton LA. Conditioned medium differentially regulates matrix protein gene expression in cells of the intervertebral disc. Spine. 29: 2217-22. PMID 15480131 DOI: 10.1097/01.Brs.0000142747.90488.1D  0.71
2004 Guilak F, Fermor B, Keefe FJ, Kraus VB, Olson SA, Pisetsky DS, Setton LA, Weinberg JB. The role of biomechanics and inflammation in cartilage injury and repair. Clinical Orthopaedics and Related Research. 17-26. PMID 15232421 DOI: 10.1097/01.Blo.0000131233.83640.91  0.46
2004 Nettles DL, Richardson WJ, Setton LA. Integrin expression in cells of the intervertebral disc. Journal of Anatomy. 204: 515-20. PMID 15198692 DOI: 10.1111/J.0021-8782.2004.00306.X  0.679
2004 Gilchrist CL, Xia JQ, Setton LA, Hsu EW. High-resolution determination of soft tissue deformations using MRI and first-order texture correlation. Ieee Transactions On Medical Imaging. 23: 546-53. PMID 15147008 DOI: 10.1109/Tmi.2004.825616  0.725
2004 Nettles DL, Vail TP, Morgan MT, Grinstaff MW, Setton LA. Photocrosslinkable hyaluronan as a scaffold for articular cartilage repair. Annals of Biomedical Engineering. 32: 391-7. PMID 15095813 DOI: 10.1023/B:Abme.0000017552.65260.94  0.715
2004 Chen J, Yan W, Setton LA. Static compression induces zonal-specific changes in gene expression for extracellular matrix and cytoskeletal proteins in intervertebral disc cells in vitro. Matrix Biology : Journal of the International Society For Matrix Biology. 22: 573-83. PMID 14996437 DOI: 10.1016/J.Matbio.2003.11.008  0.358
2004 Setton LA, Chen J. Intervertebral disc cell mechanics and biological responses to load Current Opinion in Orthopaedics. 15: 331-340. DOI: 10.1097/01.Bco.0000134822.79609.C6  0.35
2003 Upton ML, Chen J, Guilak F, Setton LA. Differential effects of static and dynamic compression on meniscal cell gene expression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 963-9. PMID 14554206 DOI: 10.1016/S0736-0266(03)00063-9  0.79
2003 Baer AE, Laursen TA, Guilak F, Setton LA. The micromechanical environment of intervertebral disc cells determined by a finite deformation, anisotropic, and biphasic finite element model. Journal of Biomechanical Engineering. 125: 1-11. PMID 12661192 DOI: 10.1115/1.1532790  0.8
2002 Wyland DJ, Guilak F, Elliott DM, Setton LA, Vail TP. Chondropathy after meniscal tear or partial meniscectomy in a canine model. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 996-1002. PMID 12382965 DOI: 10.1016/S0736-0266(02)00022-0  0.603
2002 Betre H, Setton LA, Meyer DE, Chilkoti A. Characterization of a genetically engineered elastin-like polypeptide for cartilaginous tissue repair. Biomacromolecules. 3: 910-6. PMID 12217035 DOI: 10.1021/Bm0255037  0.785
2002 Flahiff CM, Narmoneva DA, Huebner JL, Kraus VB, Guilak F, Setton LA. Osmotic loading to determine the intrinsic material properties of guinea pig knee cartilage. Journal of Biomechanics. 35: 1285-90. PMID 12163318 DOI: 10.1016/S0021-9290(02)00079-9  0.713
2002 Chen J, Baer AE, Paik PY, Yan W, Setton LA. Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity. Biochemical and Biophysical Research Communications. 293: 932-8. PMID 12051748 DOI: 10.1016/S0006-291X(02)00314-5  0.79
2002 Elliott DM, Narmoneva DA, Setton LA. Direct measurement of the Poisson's ratio of human patella cartilage in tension. Journal of Biomechanical Engineering. 124: 223-8. PMID 12002132 DOI: 10.1115/1.1449905  0.709
2002 Elliott DM, Jones R, Setton LA, Scully SP, Vail TP, Guilak F. Joint degeneration following meniscal allograft transplantation in a canine model: mechanical properties and semiquantitative histology of articular cartilage. Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the Esska. 10: 109-18. PMID 11914769 DOI: 10.1007/S001670100227  0.58
2002 Narmoneva DA, Cheung HS, Wang JY, Howell DS, Setton LA. Altered swelling behavior of femoral cartilage following joint immobilization in a canine model. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 83-91. PMID 11853094 DOI: 10.1016/S0736-0266(01)00076-6  0.666
2002 Upton ML, Chen J, Guilak F, Setton LA. Static compression inhibits matrix protein gene expression and increases collagenase gene expression in the meniscus Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 438-439.  0.756
2002 Betre H, Chilkoti A, Setton LA. A two-step chondrocyte recovery system based on thermally sensitive elastin-like polypeptide scaffolds for cartilage tissue engineering Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 1: 829-830.  0.781
2001 Narmoneva DA, Wang JY, Setton LA. A noncontacting method for material property determination for articular cartilage from osmotic loading. Biophysical Journal. 81: 3066-76. PMID 11720975 DOI: 10.1016/S0006-3495(01)75945-0  0.662
2001 Wang JY, Baer AE, Kraus VB, Setton LA. Intervertebral disc cells exhibit differences in gene expression in alginate and monolayer culture. Spine. 26: 1747-51; discussion . PMID 11493844 DOI: 10.1097/00007632-200108150-00003  0.784
2001 Elliott DM, Setton LA. Anisotropic and inhomogeneous tensile behavior of the human anulus fibrosus: Experimental measurement and material model predictions Journal of Biomechanical Engineering. 123: 256-263. PMID 11476369 DOI: 10.1115/1.1374202  0.436
2001 Baer AE, Wang JY, Kraus VB, Setton LA. Collagen gene expression and mechanical properties of intervertebral disc cell-alginate cultures. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 19: 2-10. PMID 11332616 DOI: 10.1016/S0736-0266(00)00003-6  0.798
2000 LeRoux MA, Arokoski J, Vail TP, Guilak F, Hyttinen MM, Kiviranta I, Setton LA. Simultaneous changes in the mechanical properties, quantitative collagen organization, and proteoglycan concentration of articular cartilage following canine meniscectomy. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 18: 383-92. PMID 10937624 DOI: 10.1002/Jor.1100180309  0.444
2000 Baer AE, Setton LA. The micromechanical environment of intervertebral disc cells: effect of matrix anisotropy and cell geometry predicted by a linear model. Journal of Biomechanical Engineering. 122: 245-51. PMID 10923292 DOI: 10.1115/1.429655  0.798
2000 Elliott DM, Setton LA. A linear material model for fiber-induced anisotropy of the anulus fibrosus Journal of Biomechanical Engineering. 122: 173-179. PMID 10834158 DOI: 10.1115/1.429639  0.436
2000 Lindhorst E, Vail TP, Guilak F, Wang H, Setton LA, Vilim V, Kraus VB. Longitudinal Characterization of Synovial Fluid Biomarkers in the Canine Meniscectomy Model of Osteoarthritis The Journal of Bone and Joint Surgery-American Volume. 82: 80. DOI: 10.2106/00004623-200006000-00051  0.383
2000 Elliott DM, Guilak F, Vail TP, Wang JY, Setton LA. Tensile Properties of Articular Cartilage are Altered by Meniscectomy in a Canine Model of Osteoarthritis The Journal of Bone and Joint Surgery-American Volume. 82: 54. DOI: 10.2106/00004623-200001000-00041  0.601
1999 Guilak F, Ting-Beall HP, Baer AE, Trickey WR, Erickson GR, Setton LA. Viscoelastic properties of intervertebral disc cells. Identification of two biomechanically distinct cell populations. Spine. 24: 2475-83. PMID 10626310 DOI: 10.1097/00007632-199912010-00009  0.817
1999 Setton LA, Guilak F, Hsu EW, Vail TP. Biomechanical factors in tissue engineered meniscal repair Clinical Orthopaedics and Related Research. S254-S272. PMID 10546651 DOI: 10.1097/00003086-199910001-00025  0.495
1999 Elliott DM, Guilak F, Vail TP, Wang JY, Setton LA. Tensile properties of articular cartilage are altered by meniscectomy in a canine model of osteoarthritis Journal of Orthopaedic Research. 17: 503-508. PMID 10459755 DOI: 10.1002/Jor.1100170407  0.617
1999 LeRoux MA, Guilak F, Setton LA. Compressive and shear properties of alginate gel: effects of sodium ions and alginate concentration. Journal of Biomedical Materials Research. 47: 46-53. PMID 10400879 DOI: 10.1002/(Sici)1097-4636(199910)47:1<46::Aid-Jbm6>3.0.Co;2-N  0.391
1999 Setton LA, Elliott DM, Mow VC. Altered mechanics of cartilage with osteoarthritis: Human osteoarthritis and an experimental model of joint degeneration Osteoarthritis and Cartilage. 7: 2-14. PMID 10367011 DOI: 10.1053/Joca.1998.0170  0.644
1999 Narmoneva DA, Wang JY, Setton LA. Nonuniform swelling-induced residual strains in articular cartilage. Journal of Biomechanics. 32: 401-8. PMID 10213030 DOI: 10.1016/S0021-9290(98)00184-5  0.65
1999 Setton LA, Baer AE, Wang JY, Kraus VB. Biosynthesis of intervertebral disc matrix in vitro Annual International Conference of the Ieee Engineering in Medicine and Biology - Proceedings. 2: 1325.  0.793
1998 Setton LA, Tohyama H, Mow VC. Swelling and curling behaviors of articular cartilage Journal of Biomechanical Engineering. 120: 355-361. PMID 10412403  0.483
1998 Iatridis JC, Setton LA, Foster RJ, Rawlins BA, Weidenbaum M, Mow VC. Degeneration affects the anisotropic and nonlinear behaviors of human anulus fibrosus in compression Journal of Biomechanics. 31: 535-544. PMID 9755038 DOI: 10.1016/S0021-9290(98)00046-3  0.622
1997 Iatridis JC, Setton LA, Weidenbaum M, Mow. VC. The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear Journal of Biomechanics. 30: 1005-1013. PMID 9391867 DOI: 10.1016/S0021-9290(97)00069-9  0.6
1997 Iatridis JC, Setton LA, Weidenbaum M, Mow VC. Alterations in the mechanical behavior of the human lumbar nucleus pulposus with degeneration and aging Journal of Orthopaedic Research. 15: 318-322. PMID 9167638 DOI: 10.1002/Jor.1100150224  0.619
1996 Iatridis JC, Weidenbaum M, Setton LA, Mow CV. Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc Spine. 21: 1174-1184. PMID 8727192 DOI: 10.1097/00007632-199605150-00009  0.48
1996 Ebara S, Iatridis JC, Setton LA, Foster RJ, Van Mow C, Weidenbaum M. Tensile properties of nondegenerate human lumbar anulus fibrosus Spine. 21: 452-461. PMID 8658249 DOI: 10.1097/00007632-199602150-00009  0.483
1995 Setton LA, Mow VC, Howell DS. Mechanical behavior of articular cartilage in shear is altered by transection of the anterior cruciate ligament Journal of Orthopaedic Research. 13: 473-482. PMID 7674064 DOI: 10.1002/jor.1100130402  0.484
1994 Best BA, Guilak F, Setton LA, Zhu W, Saed-Nejad F, Ratcliffe A, Weidenbaum M, Van M. Compressive mechanical properties of the human anulus fibrosus and their relationship to biochemical composition Spine. 19: 212-221. PMID 8153833 DOI: 10.1097/00007632-199401001-00017  0.407
1994 Muller FJ, Setton LA, Manicourt DH, Mow VC, Howell DS, Pita JC. Centrifugal and biochemical comparison of proteoglycan aggregates from articular cartilage in experimental joint disuse and joint instability Journal of Orthopaedic Research. 12: 498-508. PMID 8064480 DOI: 10.1002/jor.1100120406  0.494
1994 Setton LA, Mow VC, Muller FJ, Pita JC, Howell DS. Mechanical properties of canine articular cartilage are significantly altered following transection of the anterior cruciate ligament Journal of Orthopaedic Research. 12: 451-463. PMID 8064477 DOI: 10.1002/jor.1100120402  0.506
1993 Setton LA, Zhu W, Weidenbaum M, Ratcliffe A, Mow VC. Compressive properties of the cartilaginous End-Plate of the baboon lumbar spine Journal of Orthopaedic Research. 11: 228-239. PMID 8483035 DOI: 10.1002/jor.1100110210  0.454
1993 Setton LA, Zhu W, Mow VC. The biphasic poroviscoelastic behavior of articular cartilage: Role of the surface zone in governing the compressive behavior Journal of Biomechanics. 26: 581-592. PMID 8478359 DOI: 10.1016/0021-9290(93)90019-B  0.483
1993 Setton LA, Mow VC, Muller FJ, Pita JC, Howell DS. Altered structure-function relationships for articular cartilage in human osteoarthritis and an experimental canine model Agents and Actions. 39: 27-48. PMID 8456641  0.516
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