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Liquan Huang - Publications

Affiliations: 
Monell Chemical Senses Center, Philadelphia, PA, United States 
Website:
http://www.monell.org/faculty/people/liquan_huang

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Lei H, Yu D, Xue YB, Li YH, Gong SM, Peng YY, Liu KF, Buratto D, Yang Y, Zhang SS, Wu M, Zhou R, Huang L. Tuft cells utilize taste signaling molecules to respond to the pathobiont microbe in the proximal colon. Frontiers in Immunology. 14: 1259521. PMID 37954611 DOI: 10.3389/fimmu.2023.1259521  0.367
2023 Lin C, Jyotaki M, Quinlan J, Feng S, Zhou M, Jiang P, Matsumoto I, Huang L, Ninomiya Y, Margolskee RF, Reed DR, Wang H. Lipopolysaccharide increases bitter taste sensitivity via epigenetic changes in gene clusters. Iscience. 26: 106920. PMID 37283808 DOI: 10.1016/j.isci.2023.106920  0.592
2023 Lin C, Jyotaki M, Quinlan J, Feng S, Zhou M, Jiang P, Matsumoto I, Huang L, Ninomiya Y, Margolskee RF, Reed DR, Wang H. Inflammation induces bitter taste oversensitization via epigenetic changes in gene clusters. Biorxiv : the Preprint Server For Biology. PMID 36798225 DOI: 10.1101/2023.02.08.527520  0.599
2022 Zheng X, Zhu J, Liu J, Wang H, Qin Y, Jiang P, Xiao L, Gong T, Li Y, Peng X, Xu X, Cheng L, Huang L, Chen Q, Zhou X, et al. Sweet taste perception in mice is blunted by PTBP1-regulated skipping of Tas1r2 exon 4. Chemical Senses. 47. PMID 36484118 DOI: 10.1093/chemse/bjac034  0.624
2020 Chen ZH, Luo XC, Yu CR, Huang L. Matrix metalloprotease-mediated cleavage of neural glial-related cell adhesion molecules activates quiescent olfactory stem cells via EGFR. Molecular and Cellular Neurosciences. 103552. PMID 32918999 DOI: 10.1016/J.Mcn.2020.103552  0.383
2019 Liu Q, Zhang Y, Wang P, Guo X, Wu Y, Zhang JX, Huang L. Two Preputial Gland-Secreted Pheromones Evoke Sexually Dimorphic Neural Pathways in the Mouse Vomeronasal System. Frontiers in Cellular Neuroscience. 13: 455. PMID 31632243 DOI: 10.3389/Fncel.2019.00455  0.319
2019 Wang J, Kong S, Chen F, Chen W, Du L, Cai W, Huang L, Wu C, Zhang DW. A bioelectronic taste sensor based on bioengineered Escherichia coli cells combined with ITO-constructed electrochemical sensors. Analytica Chimica Acta. 1079: 73-78. PMID 31387721 DOI: 10.1016/J.Aca.2019.06.023  0.379
2019 Qin C, Qin Z, Zhao D, Pan Y, Zhuang L, Wan H, Di Pizio A, Malach E, Niv MY, Huang L, Hu N, Wang P. A bioinspired in vitro bioelectronic tongue with human T2R38 receptor for high-specificity detection of N-C=S-containing compounds. Talanta. 199: 131-139. PMID 30952236 DOI: 10.1016/J.Talanta.2019.02.021  0.425
2019 Luo XC, Chen ZH, Xue JB, Zhao DX, Lu C, Li YH, Li SM, Du YW, Liu Q, Wang P, Liu M, Huang L. Infection by the parasitic helminth activates a Tas2r-mediated signaling pathway in intestinal tuft cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30819885 DOI: 10.1073/Pnas.1812901116  0.464
2018 Du YW, Liu Q, Luo XC, Zhao DX, Xue JB, Feng P, Margolskee RF, Wang H, Huang L. Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model. Journal of Visualized Experiments : Jove. PMID 30474644 DOI: 10.3791/58668  0.591
2018 Liu Q, Li S, Lu C, Yu CR, Huang L. G protein γ subunit Gγ13 is essential for olfactory function and aggressive behavior in mice. Neuroreport. PMID 30157062 DOI: 10.1097/Wnr.0000000000001122  0.426
2018 Feng P, Chai J, Yi H, Redding K, Margolskee RF, Huang L, Wang H. Aggravated gut inflammation in mice lacking the taste signaling protein α-gustducin. Brain, Behavior, and Immunity. PMID 29678794 DOI: 10.1016/J.Bbi.2018.04.010  0.629
2018 Zhong C, Chen Z, Luo X, Wang C, Jiang H, Shao J, Guan M, Huang L, Huang X, Wang J. Corrigendum to "Barhl1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells" [Int. J. Biochem. Cell Biol. 96 (2018) 79-89]. The International Journal of Biochemistry & Cell Biology. PMID 29477628 DOI: 10.1016/J.Biocel.2018.02.009  0.371
2018 Zhong C, Chen Z, Luo X, Wang C, Jiang H, Shao J, Guan M, Huang L, Huang X, Wang J. Barhl1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells. The International Journal of Biochemistry & Cell Biology. 96: 79-89. PMID 29413750 DOI: 10.1016/J.Biocel.2018.01.013  0.405
2017 Wu C, Du YW, Huang L, Ben-Shoshan Galeczki Y, Dagan-Wiener A, Naim M, Niv MY, Wang P. Biomimetic Sensors for the Senses: Towards Better Understanding of Taste and Odor Sensation. Sensors (Basel, Switzerland). 17. PMID 29232897 DOI: 10.3390/S17122881  0.388
2017 Gao K, Li S, Zhuang L, Qin Z, Zhang B, Huang L, Wang P. In vivo bioelectronic nose using transgenic mice for specific odor detection. Biosensors & Bioelectronics. 102: 150-156. PMID 29128717 DOI: 10.1016/J.Bios.2017.08.055  0.352
2017 Hu L, Zou L, Qin Z, Fang J, Huang L, Wang P. A novel label-free bioengineered cell-based biosensor for salicin detection Sensors and Actuators B: Chemical. 238: 1151-1158. DOI: 10.1016/J.Snb.2016.02.072  0.413
2016 Hu L, Xu J, Qin Z, Hu N, Zhou M, Huang L, Wang P. Detection of bitterness in vitro by a novel male mouse germ cell-based biosensor Sensors and Actuators, B: Chemical. 223: 461-469. DOI: 10.1016/J.Snb.2015.08.105  0.469
2015 Zhong C, Zhou YK, Yang SS, Zhao JF, Zhu XL, Chen HH, Chen PC, Huang LQ, Huang X. Developmental expression of the N-myc downstream regulated gene (Ndrg) family during Xenopus tropicalis embryogenesis. The International Journal of Developmental Biology. 59: 511-517. PMID 26864492 DOI: 10.1387/Ijdb.150178Xh  0.324
2015 Challis RC, Tian H, Wang J, He J, Jiang J, Chen X, Yin W, Connelly T, Ma L, Yu CR, Pluznick JL, Storm DR, Huang L, Zhao K, Ma M. An Olfactory Cilia Pattern in the Mammalian Nose Ensures High Sensitivity to Odors. Current Biology : Cb. PMID 26365258 DOI: 10.1016/J.Cub.2015.07.065  0.365
2015 Feng P, Jyotaki M, Kim A, Chai J, Simon N, Zhou M, Bachmanov AA, Huang L, Wang H. Regulation of bitter taste responses by tumor necrosis factor. Brain, Behavior, and Immunity. 49: 32-42. PMID 25911043 DOI: 10.1016/J.Bbi.2015.04.001  0.409
2015 Malach E, Shaul ME, Peri I, Huang L, Spielman AI, Seger R, Naim M. Membrane-permeable tastants amplify β2-adrenergic receptor signaling and delay receptor desensitization via intracellular inhibition of GRK2's kinase activity. Biochimica Et Biophysica Acta. 1850: 1375-88. PMID 25857770 DOI: 10.1016/J.Bbagen.2015.03.015  0.32
2015 Du L, Zou L, Wang Q, Zhao L, Huang L, Wang P, Wu C. A novel biomimetic olfactory cell-based biosensor with DNA-directed site-specific immobilization of cells on a microelectrode array Sensors and Actuators, B: Chemical. 217: 186-192. DOI: 10.1016/J.Snb.2014.08.054  0.389
2014 Feng P, Chai J, Zhou M, Simon N, Huang L, Wang H. Interleukin-10 is produced by a specific subset of taste receptor cells and critical for maintaining structural integrity of mouse taste buds. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2689-701. PMID 24523558 DOI: 10.1523/Jneurosci.3074-13.2014  0.437
2014 Du L, Zou L, Zhao L, Huang L, Wang P, Wu C. Label-free functional assays of chemical receptors using a bioengineered cell-based biosensor with localized extracellular acidification measurement. Biosensors & Bioelectronics. 54: 623-7. PMID 24333934 DOI: 10.1016/J.Bios.2013.11.049  0.488
2014 Feng P, Huang L, Wang H. Taste bud homeostasis in health, disease, and aging. Chemical Senses. 39: 3-16. PMID 24287552 DOI: 10.1093/Chemse/Bjt059  0.466
2014 Wu C, Du L, Zou L, Zhao L, Huang L, Wang P. Recent advances in taste cell- and receptor-based biosensors Sensors and Actuators, B: Chemical. 201: 75-85. DOI: 10.1016/J.Snb.2014.04.021  0.483
2013 Wu C, Du L, Zou L, Huang L, Wang P. A biomimetic bitter receptor-based biosensor with high efficiency immobilization and purification using self-assembled aptamers. The Analyst. 138: 5989-94. PMID 23951570 DOI: 10.1039/C3An01291C  0.422
2013 Li F, Ponissery-Saidu S, Yee KK, Wang H, Chen ML, Iguchi N, Zhang G, Jiang P, Reisert J, Huang L. Heterotrimeric G protein subunit Gγ13 is critical to olfaction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7975-84. PMID 23637188 DOI: 10.1523/Jneurosci.5563-12.2013  0.422
2013 Du L, Wu C, Liu Q, Huang L, Wang P. Recent advances in olfactory receptor-based biosensors. Biosensors & Bioelectronics. 42: 570-80. PMID 23261691 DOI: 10.1016/J.Bios.2012.09.001  0.35
2013 Du L, Wu C, Peng H, Zhao L, Huang L, Wang P. Bioengineered olfactory sensory neuron-based biosensor for specific odorant detection. Biosensors & Bioelectronics. 40: 401-6. PMID 23036770 DOI: 10.1016/J.Bios.2012.08.035  0.389
2013 Xu J, Cao J, Iguchi N, Riethmacher D, Huang L. Functional characterization of bitter-taste receptors expressed in mammalian testis. Molecular Human Reproduction. 19: 17-28. PMID 22983952 DOI: 10.1093/Molehr/Gas040  0.541
2013 Du L, Wu C, Peng H, Zou L, Zhao L, Huang L, Wang P. Piezoelectric olfactory receptor biosensor prepared by aptamer-assisted immobilization Sensors and Actuators, B: Chemical. 187: 481-487. DOI: 10.1016/J.Snb.2013.02.009  0.396
2012 Zhu X, Li Z, Jiang D, Zhao J, Huang L, Zhang J, Huang X. Characterization and expressional analysis of Dleu7 during Xenopus tropicalis embryogenesis. Gene. 509: 77-84. PMID 22939871 DOI: 10.1016/J.Gene.2012.08.024  0.394
2012 Feng P, Zhao H, Chai J, Huang L, Wang H. Expression and secretion of TNF-α in mouse taste buds: a novel function of a specific subset of type II taste cells. Plos One. 7: e43140. PMID 22905218 DOI: 10.1371/Journal.Pone.0043140  0.436
2012 Kim A, Feng P, Ohkuri T, Sauers D, Cohn ZJ, Chai J, Nelson T, Bachmanov AA, Huang L, Wang H. Defects in the peripheral taste structure and function in the MRL/lpr mouse model of autoimmune disease. Plos One. 7: e35588. PMID 22536412 DOI: 10.1371/Journal.Pone.0035588  0.434
2011 Iguchi N, Ohkuri T, Slack JP, Zhong P, Huang L. Sarco/Endoplasmic reticulum Ca2+-ATPases (SERCA) contribute to GPCR-mediated taste perception. Plos One. 6: e23165. PMID 21829714 DOI: 10.1371/Journal.Pone.0023165  0.353
2010 Cohn ZJ, Kim A, Huang L, Brand J, Wang H. Lipopolysaccharide-induced inflammation attenuates taste progenitor cell proliferation and shortens the life span of taste bud cells. Bmc Neuroscience. 11: 72. PMID 20537148 DOI: 10.1186/1471-2202-11-72  0.472
2009 Wang H, Zhou M, Brand J, Huang L. Inflammation and taste disorders: mechanisms in taste buds. Annals of the New York Academy of Sciences. 1170: 596-603. PMID 19686199 DOI: 10.1111/J.1749-6632.2009.04480.X  0.493
2009 Maehashi K, Huang L. Bitter peptides and bitter taste receptors Cellular and Molecular Life Sciences. 66: 1661-1671. PMID 19153652 DOI: 10.1007/S00018-009-8755-9  0.378
2009 Wang H, Iguchi N, Rong Q, Zhou M, Ogunkorode M, Inoue M, Pribitkin EA, Bachmanov AA, Margolskee RF, Pfeifer K, Huang L. Expression of the voltage-gated potassium channel KCNQ1 in mammalian taste bud cells and the effect of its null-mutation on taste preferences. The Journal of Comparative Neurology. 512: 384-98. PMID 19006182 DOI: 10.1002/Cne.21899  0.65
2008 Maehashi K, Matano M, Wang H, Vo LA, Yamamoto Y, Huang L. Bitter peptides activate hTAS2Rs, the human bitter receptors. Biochemical and Biophysical Research Communications. 365: 851-5. PMID 18037373 DOI: 10.1016/J.Bbrc.2007.11.070  0.34
2008 Naim M, Shaul ME, Spielman AI, Huang L, Peri I. Permeation of amphipathic sweeteners into taste-bud cells and their interactions with post-receptor signaling components: Possible implications for sweet-taste quality Acs Symposium Series. 979: 241-255. DOI: 10.1021/bk-2008-0979.ch017  0.301
2007 Wang H, Zhou M, Brand J, Huang L. Inflammation activates the interferon signaling pathways in taste bud cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 10703-13. PMID 17913904 DOI: 10.1523/Jneurosci.3102-07.2007  0.466
2006 Li X, Li W, Wang H, Bayley DL, Cao J, Reed DR, Bachmanov AA, Huang L, Legrand-Defretin V, Beauchamp GK, Brand JG. Cats lack a sweet taste receptor. The Journal of Nutrition. 136: 1932S-1934S. PMID 16772462 DOI: 10.1093/Jn/136.7.1932S  0.436
2006 Breslin PA, Huang L. Human taste: peripheral anatomy, taste transduction, and coding. Advances in Oto-Rhino-Laryngology. 63: 152-90. PMID 16733339 DOI: 10.1159/000093760  0.356
2005 Huang L, Cao J, Wang H, Vo LA, Brand JG. Identification and functional characterization of a voltage-gated chloride channel and its novel splice variant in taste bud cells. The Journal of Biological Chemistry. 280: 36150-7. PMID 16129671 DOI: 10.1074/Jbc.M507706200  0.334
2005 Li X, Li W, Wang H, Cao J, Maehashi K, Huang L, Bachmanov AA, Reed DR, Legrand-Defretin V, Beauchamp GK, Brand JG. Pseudogenization of a sweet-receptor gene accounts for cats' indifference toward sugar. Plos Genetics. 1: 27-35. PMID 16103917 DOI: 10.1371/Journal.Pgen.0010003  0.458
2005 Lu K, McDaniel AH, Tordoff MG, Li X, Beauchamp GK, Bachmanov AA, VanderWeele DA, Chapman CD, Dess NK, Huang L, Wang H, Reed DR. No relationship between sequence variation in protein coding regions of the Tas1r3 gene and saccharin preference in rats. Chemical Senses. 30: 231-40. PMID 15741599 DOI: 10.1093/Chemse/Bji019  0.331
2004 Reed DR, Li S, Li X, Huang L, Tordoff MG, Starling-Roney R, Taniguchi K, West DB, Ohmen JD, Beauchamp GK, Bachmanov AA. Polymorphisms in the taste receptor gene (Tas1r3) region are associated with saccharin preference in 30 mouse strains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 938-46. PMID 14749438 DOI: 10.1523/Jneurosci.1374-03.2004  0.351
2003 Huang L, Max M, Margolskee RF, Su H, Masland RH, Euler T. G protein subunit G gamma 13 is coexpressed with G alpha o, G beta 3, and G beta 4 in retinal ON bipolar cells. The Journal of Comparative Neurology. 455: 1-10. PMID 12454992 DOI: 10.1002/Cne.10396  0.671
2002 Pérez CA, Huang L, Rong M, Kozak JA, Preuss AK, Zhang H, Max M, Margolskee RF. A transient receptor potential channel expressed in taste receptor cells. Nature Neuroscience. 5: 1169-76. PMID 12368808 DOI: 10.1038/nn952  0.731
2001 Max M, Shanker YG, Huang L, Rong M, Liu Z, Campagne F, Weinstein H, Damak S, Margolskee RF. Tas1r3, encoding a new candidate taste receptor, is allelic to the sweet responsiveness locus Sac. Nature Genetics. 28: 58-63. PMID 11326277 DOI: 10.1038/Ng0501-58  0.686
1999 Huang L, Shanker YG, Dubauskaite J, Zheng JZ, Yan W, Rosenzweig S, Spielman AI, Max M, Margolskee RF. Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. Nature Neuroscience. 2: 1055-62. PMID 10570481 DOI: 10.1038/15981  0.681
1996 Lerner MR, Golovyan L, Graminski GF, Harris K, Huang L, Jayawickreme CK, Karne S, McClintock TS, Potenza MN, Roby-Shemkovitz A, Quillan M. Tools for Investigating Functional Interactions Between Lipid-Derived Autacoids and their Receptors. American Journal of Therapeutics. 3: 280-286. PMID 11862262 DOI: 10.1097/00045391-199604000-00005  0.366
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