| Year |
Citation |
Score |
| 2023 |
Loose S, Lischka A, Kuehs S, Nau C, Heinemann SH, Kurth I, Leipold E. Peripheral temperature dysregulation associated with functionally altered Na1.8 channels. Pflugers Archiv : European Journal of Physiology. 475: 1343-1355. PMID 37695396 DOI: 10.1007/s00424-023-02856-2 |
0.361 |
|
| 2018 |
Niedermirtl F, Eberhardt M, Namer B, Leffler A, Nau C, Reeh PW, Kistner K. [EXPRESS] Etomidate and propylene glycol activate nociceptive TRP ion channels. Molecular Pain. 1744806918811699. PMID 30345869 DOI: 10.1177/1744806918811699 |
0.309 |
|
| 2017 |
O'Reilly AO, Lattrell A, Miles AJ, Klinger AB, Nau C, Wallace BA, Lampert A. Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine. European Biophysics Journal : Ebj. PMID 28825121 DOI: 10.1007/s00249-017-1246-2 |
0.442 |
|
| 2017 |
Nau C, Leipold E. Voltage-gated sodium channels and pain E-Neuroforum. 23. DOI: 10.1515/nf-2017-A017 |
0.319 |
|
| 2015 |
Eberhardt E, Havlicek S, Schmidt D, Link AS, Neacsu C, Kohl Z, Hampl M, Kist AM, Klinger A, Nau C, Schüttler J, Alzheimer C, Winkler J, Namer B, Winner B, et al. Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors. Stem Cell Reports. 5: 305-13. PMID 26321143 DOI: 10.1016/j.stemcr.2015.07.010 |
0.399 |
|
| 2014 |
Eberhardt M, Nakajima J, Klinger AB, Neacsu C, Hühne K, O'Reilly AO, Kist AM, Lampe AK, Fischer K, Gibson J, Nau C, Winterpacht A, Lampert A. Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation. The Journal of Biological Chemistry. 289: 1971-80. PMID 24311784 DOI: 10.1074/jbc.M113.502211 |
0.364 |
|
| 2012 |
Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, Sauer SK, Eberhardt M, Schnölzer M, Lasitschka F, Lasischka F, Neuhuber WL, Kichko TI, Konrade I, Elvert R, ... ... Nau C, et al. Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nature Medicine. 18: 926-33. PMID 22581285 DOI: 10.1038/nm.2750 |
0.347 |
|
| 2012 |
Leffler A, Frank G, Kistner K, Niedermirtl F, Koppert W, Reeh PW, Nau C. Local anesthetic-like inhibition of voltage-gated Na(+) channels by the partial μ-opioid receptor agonist buprenorphine. Anesthesiology. 116: 1335-46. PMID 22504149 DOI: 10.1097/ALN.0b013e3182557917 |
0.411 |
|
| 2011 |
Leffler A, Lattrell A, Kronewald S, Niedermirtl F, Nau C. Activation of TRPA1 by membrane permeable local anesthetics. Molecular Pain. 7: 62. PMID 21861907 DOI: 10.1186/1744-8069-7-62 |
0.376 |
|
| 2011 |
Engel MA, Leffler A, Niedermirtl F, Babes A, Zimmermann K, Filipović MR, Izydorczyk I, Eberhardt M, Kichko TI, Mueller-Tribbensee SM, Khalil M, Siklosi N, Nau C, Ivanović-Burmazović I, Neuhuber WL, et al. TRPA1 and substance P mediate colitis in mice. Gastroenterology. 141: 1346-58. PMID 21763243 DOI: 10.1053/j.gastro.2011.07.002 |
0.322 |
|
| 2010 |
Fischer MJ, Leffler A, Niedermirtl F, Kistner K, Eberhardt M, Reeh PW, Nau C. The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors. The Journal of Biological Chemistry. 285: 34781-92. PMID 20826794 DOI: 10.1074/jbc.M110.143958 |
0.341 |
|
| 2010 |
Choi JS, Cheng X, Foster E, Leffler A, Tyrrell L, Te Morsche RH, Eastman EM, Jansen HJ, Huehne K, Nau C, Dib-Hajj SD, Drenth JP, Waxman SG. Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia. Brain : a Journal of Neurology. 133: 1823-35. PMID 20478850 DOI: 10.1093/brain/awq114 |
0.419 |
|
| 2010 |
Leffler A, Reckzeh J, Nau C. Block of sensory neuronal Na+ channels by the secreolytic ambroxol is associated with an interaction with local anesthetic binding sites. European Journal of Pharmacology. 630: 19-28. PMID 20044988 DOI: 10.1016/j.ejphar.2009.12.027 |
0.451 |
|
| 2009 |
Herold KF, Nau C, Ouyang W, Hemmings HC. Isoflurane inhibits the tetrodotoxin-resistant voltage-gated sodium channel Nav1.8. Anesthesiology. 111: 591-9. PMID 19672182 DOI: 10.1097/ALN.0b013e3181af64d4 |
0.457 |
|
| 2008 |
Wang CF, Gerner P, Schmidt B, Xu ZZ, Nau C, Wang SY, Ji RR, Wang GK. Use of bulleyaconitine A as an adjuvant for prolonged cutaneous analgesia in the rat. Anesthesia and Analgesia. 107: 1397-405. PMID 18806059 DOI: 10.1213/ane.0b013e318182401b |
0.423 |
|
| 2008 |
Harrison N, Nau C. Sensitization of nociceptive ion channels by inhaled anesthetics--a pain in the gas? Molecular Pharmacology. 74: 1180-2. PMID 18768735 DOI: 10.1124/mol.108.051615 |
0.39 |
|
| 2008 |
Leffler A, Fischer MJ, Rehner D, Kienel S, Kistner K, Sauer SK, Gavva NR, Reeh PW, Nau C. The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons. The Journal of Clinical Investigation. 118: 763-76. PMID 18172555 DOI: 10.1172/JCI32751 |
0.445 |
|
| 2007 |
Leffler A, Linte RM, Nau C, Reeh P, Babes A. A high-threshold heat-activated channel in cultured rat dorsal root ganglion neurons resembles TRPV2 and is blocked by gadolinium. The European Journal of Neuroscience. 26: 12-22. PMID 17596195 DOI: 10.1111/j.1460-9568.2007.05643.x |
0.368 |
|
| 2007 |
Zimmermann K, Leffler A, Babes A, Cendan CM, Carr RW, Kobayashi J, Nau C, Wood JN, Reeh PW. Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures. Nature. 447: 855-8. PMID 17568746 DOI: 10.1038/nature05880 |
0.42 |
|
| 2007 |
Leffler A, Reiprich A, Mohapatra DP, Nau C. Use-dependent block by lidocaine but not amitriptyline is more pronounced in tetrodotoxin (TTX)-Resistant Nav1.8 than in TTX-sensitive Na+ channels. The Journal of Pharmacology and Experimental Therapeutics. 320: 354-64. PMID 17005919 DOI: 10.1124/Jpet.106.109025 |
0.483 |
|
| 2005 |
Mohapatra DP, Nau C. Regulation of Ca2+-dependent desensitization in the vanilloid receptor TRPV1 by calcineurin and cAMP-dependent protein kinase. The Journal of Biological Chemistry. 280: 13424-32. PMID 15691846 DOI: 10.1074/Jbc.M410917200 |
0.432 |
|
| 2004 |
Nau C, Wang GK. Interactions of local anesthetics with voltage-gated Na+ channels. The Journal of Membrane Biology. 201: 1-8. PMID 15635807 DOI: 10.1007/s00232-004-0702-y |
0.353 |
|
| 2003 |
Mohapatra DP, Nau C. Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway. The Journal of Biological Chemistry. 278: 50080-90. PMID 14506258 DOI: 10.1074/Jbc.M306619200 |
0.437 |
|
| 2003 |
Mohapatra DP, Wang SY, Wang GK, Nau C. A tyrosine residue in TM6 of the Vanilloid Receptor TRPV1 involved in desensitization and calcium permeability of capsaicin-activated currents. Molecular and Cellular Neurosciences. 23: 314-24. PMID 12812762 DOI: 10.1016/S1044-7431(03)00054-X |
0.411 |
|
| 2003 |
Nau C, Wang SY, Wang GK. Point mutations at L1280 in Nav1.4 channel D3-S6 modulate binding affinity and stereoselectivity of bupivacaine enantiomers. Molecular Pharmacology. 63: 1398-406. PMID 12761351 DOI: 10.1124/mol.63.6.1398 |
0.452 |
|
| 2002 |
Nau C, Strichartz GR. Drug chirality in anesthesia. Anesthesiology. 97: 497-502. PMID 12151942 DOI: 10.1097/00000542-200208000-00029 |
0.426 |
|
| 2002 |
Rathee PK, Distler C, Obreja O, Neuhuber W, Wang GK, Wang SY, Nau C, Kress M. PKA/AKAP/VR-1 module: A common link of Gs-mediated signaling to thermal hyperalgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4740-5. PMID 12040081 DOI: 10.1523/Jneurosci.22-11-04740.2002 |
0.351 |
|
| 2000 |
Nau C, Wang SY, Strichartz GR, Wang GK. Block of human heart hH1 sodium channels by the enantiomers of bupivacaine. Anesthesiology. 93: 1022-33. PMID 11020758 DOI: 10.1097/00000542-200010000-00026 |
0.59 |
|
| 2000 |
Vladimirov M, Nau C, Mok WM, Strichartz G. Potency of bupivacaine stereoisomers tested in vitro and in vivo: biochemical, electrophysiological, and neurobehavioral studies. Anesthesiology. 93: 744-55. PMID 10969308 DOI: 10.1097/00000542-200009000-00024 |
0.568 |
|
| 2000 |
Wang SY, Nau C, Wang GK. Residues in Na(+) channel D3-S6 segment modulate both batrachotoxin and local anesthetic affinities. Biophysical Journal. 79: 1379-87. PMID 10969000 DOI: 10.1016/S0006-3495(00)76390-9 |
0.435 |
|
| 2000 |
Nau C, Seaver M, Wang SY, Wang GK. Block of human heart hH1 sodium channels by amitriptyline. The Journal of Pharmacology and Experimental Therapeutics. 292: 1015-23. PMID 10688618 |
0.378 |
|
| 1999 |
Nau C, Vogel W, Hempelmann G, Bräu ME. Stereoselectivity of bupivacaine in local anesthetic-sensitive ion channels of peripheral nerve. Anesthesiology. 91: 786-95. PMID 10485790 DOI: 10.1097/00000542-199909000-00031 |
0.309 |
|
| 1999 |
Nau C, Wang SY, Strichartz GR, Wang GK. Point mutations at N434 in D1-S6 of mu1 Na(+) channels modulate binding affinity and stereoselectivity of local anesthetic enantiomers. Molecular Pharmacology. 56: 404-13. PMID 10419561 |
0.538 |
|
| 1998 |
Nau C, Strichartz GR. MEMBRANE POTENTIAL REVERSES STEREO-SELECTIVITY OF BUPIVACAINE ENANTIOMERS TO BLOCK SODIUM CURRENT IN RAT GH3 CELLS Anesthesiology. 89: 882A. DOI: 10.1097/00000542-199809150-00057 |
0.496 |
|
| 1995 |
Bräu ME, Nau C, Hempelmann G, Vogel W. Local anesthetics potently block a potential insensitive potassium channel in myelinated nerve. The Journal of General Physiology. 105: 485-505. PMID 7608655 |
0.349 |
|
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