☰

Deanna L. Kroetz - Publications

Affiliations: 
Biopharmaceutical Sciences University of California, San Francisco, San Francisco, CA 
Area:
pharmacology, drug metabolism
Website:
http://cancer.ucsf.edu/people/profiles/kroetz_deanna.3347
Tree Info Similar researchers PubMed Report error

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chua KC, Xiong C, Ho C, Mushiroda T, Jiang C, Mulkey F, Lai D, Schneider BP, Rashkin SR, Witte JS, Friedman PN, Ratain MJ, McLeod HL, Rugo HS, Shulman LN, ... ... Kroetz DL, et al. Genome-Wide Meta-Analysis Validates a Roless for S1PR1 in Microtubule Targeting Agent-Induced Sensory Peripheral Neuropathy. Clinical Pharmacology and Therapeutics. PMID 32562552 DOI: 10.1002/Cpt.1958  0.359
2020 Stage TB, Mortensen C, Khalaf S, Steffensen V, Hammer HS, Xiong C, Nielsen F, Poetz O, Svenningsen ÅF, Rodriguez-Antona C, Kroetz DL. P-glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Cancer Patients. Clinical Pharmacology and Therapeutics. PMID 32275773 DOI: 10.1002/Cpt.1847  0.318
2019 Levy ES, Samy KE, Lamson NG, Whitehead KA, Kroetz DL, Desai TA. Reversible Inhibition of Efflux Transporters by Hydrogel Microdevices. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 31639417 DOI: 10.1016/J.Ejpb.2019.10.007  0.393
2019 Yee SW, Giacomini MM, Shen H, Humphreys WG, Horng H, Brian W, Lai Y, Kroetz DL, Giacomini KM. Organic Anion Transporter Polypeptide 1B1 Polymorphism Modulates the Extent of Drug-Drug Interaction and Associated Biomarker Levels in Healthy Volunteers. Clinical and Translational Science. PMID 30982223 DOI: 10.1111/Cts.12625  0.362
2019 Jayagopal A, Brakeman P, Soler P, Ferrell N, Fissell W, Kroetz DL, Roy S. Apical Shear Stress Enhanced Organic Cation Transport in hOCT2/hMATE1 Transfected MDCK Cells Involves Ciliary Sensing. The Journal of Pharmacology and Experimental Therapeutics. PMID 30910922 DOI: 10.1124/Jpet.118.255026  0.333
2018 Chang JL, Lee S, Tsai AC, Musinguzi N, Muzoora C, Bwana BM, Boum Y, Haberer J, Hunt PW, Martin J, Bangsberg DR, Kroetz DL, Siedner MJ. CYP2B6 genetic polymorphisms, depression, and viral suppression in adults living with HIV initiating efavirenz-containing antiretroviral therapy regimens in Uganda: pooled analysis of two prospective studies. Aids Research and Human Retroviruses. PMID 29973058 DOI: 10.1089/Aid.2018.0062  0.306
2018 Eclov RJ, Kim MJ, Smith RP, Ahituv N, Kroetz DL. Rare Variants in the ABCG2 Promoter Modulate In Vivo Activity. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29467213 DOI: 10.1124/Dmd.117.079541  0.773
2017 Eclov RJ, Kim MJ, Chhibber A, Smith RP, Ahituv N, Kroetz DL. ABCG2 regulatory single-nucleotide polymorphisms alter in-vivo enhancer activity and expression. Pharmacogenetics and Genomics. PMID 28930109 DOI: 10.1097/Fpc.0000000000000312  0.774
2016 Chua KC, Kroetz DL. Genetic Advances Uncover Mechanisms of Chemotherapy-Induced Peripheral Neuropathy. Clinical Pharmacology and Therapeutics. PMID 27981569 DOI: 10.1002/Cpt.590  0.306
2016 Eclov RJ, Kim MJ, Smith RP, Liang X, Ahituv N, Kroetz DL. In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27856528 DOI: 10.1124/Dmd.116.072033  0.783
2016 Li M, Seiser EL, Baldwin RM, Ramirez J, Ratain MJ, Innocenti F, Kroetz DL. ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia. The Pharmacogenomics Journal. PMID 27845419 DOI: 10.1038/Tpj.2016.75  0.419
2016 Yee SW, Giacomini MM, Hsueh CH, Weitz D, Liang X, Goswami S, Kinchen JM, Coelho A, Zur AA, Mertsch K, Brian W, Kroetz DL, Giacomini KM. Metabolomic and Genome-wide Association Studies Reveal Potential Endogenous Biomarkers for OATP1B1. Clinical Pharmacology and Therapeutics. PMID 27447836 DOI: 10.1002/Cpt.434  0.384
2016 Hertz DL, Owzar K, Lessans S, Wing C, Jiang C, Kelly WK, Patel JN, Halabi S, Furukawa Y, Wheeler HE, Sibley A, Lassiter C, Weisman LS, Watson D, Krens SD, ... ... Kroetz D, et al. Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism That Increases Risk of Docetaxel-Induced Neuropathy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27143689 DOI: 10.1158/1078-0432.Ccr-15-2823  0.314
2016 Chhibber A, French CE, Yee SW, Gamazon ER, Theusch E, Qin X, Webb A, Papp AC, Wang A, Simmons CQ, Konkashbaev A, Chaudhry AS, Mitchel K, Stryke D, Ferrin TE, ... ... Kroetz DL, et al. Transcriptomic variation of pharmacogenes in multiple human tissues and lymphoblastoid cell lines. The Pharmacogenomics Journal. PMID 26856248 DOI: 10.1038/Tpj.2015.93  0.641
2015 Yuan B, Yoshino Y, Fukushima H, Markova S, Takagi N, Toyoda H, Kroetz DL. Multidrug resistance-associated protein 4 is a determinant of arsenite resistance. Oncology Reports. PMID 26497925 DOI: 10.3892/Or.2015.4343  0.335
2015 Komatsu M, Wheeler HE, Chung S, Low SK, Wing C, Delaney SM, Gorsic LK, Takahashi A, Kubo M, Kroetz D, Zhang W, Nakamura Y, Dolan ME. Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26015512 DOI: 10.1158/1078-0432.Ccr-15-0133  0.303
2015 Haenisch S, Zhao Y, Chhibber A, Kaiboriboon K, Do LV, Vogelgesang S, Barbaro NM, Alldredge BK, Lowenstein DH, Cascorbi I, Kroetz DL. SOX11 identified by target gene evaluation of miRNAs differentially expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients. Neurobiology of Disease. 77: 127-40. PMID 25766675 DOI: 10.1016/J.Nbd.2015.02.025  0.617
2015 Barbarino JM, Kroetz DL, Klein TE, Altman RB. PharmGKB summary: very important pharmacogene information for human leukocyte antigen B. Pharmacogenetics and Genomics. 25: 205-21. PMID 25647431 DOI: 10.1097/Fpc.0000000000000118  0.309
2014 Espin-Garcia O, Liu G, Owzar K, Kroetz D, Marsh S, Perrin T, Adusei C, Farrelly L, Embleton A, Swart AM, Parmar MK, Kaplan R, Kubo M, Ratain MJ, Matsuda K, et al. 180PGENOME-WIDE ASSOCIATION STUDY (GWAS) IDENTIFIES CANDIDATE NEUROTOXICITY MARKERS IN PLATINUM-TAXANE TREATED OVARIAN CANCER PATIENTS IN ICON7. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv62-iv63. PMID 28172135 DOI: 10.1093/Annonc/Mdu326.14  0.35
2014 Chhibber A, Kroetz DL, Tantisira KG, McGeachie M, Cheng C, Plenge R, Stahl E, Sadee W, Ritchie MD, Pendergrass SA. Genomic architecture of pharmacological efficacy and adverse events. Pharmacogenomics. 15: 2025-48. PMID 25521360 DOI: 10.2217/Pgs.14.144  0.65
2014 Chhibber A, Mefford J, Stahl EA, Pendergrass SA, Baldwin RM, Owzar K, Li M, Winer EP, Hudis CA, Zembutsu H, Kubo M, Nakamura Y, McLeod HL, Ratain MJ, Shulman LN, ... ... Kroetz DL, et al. Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance). The Pharmacogenomics Journal. 14: 336-42. PMID 24513692 DOI: 10.1038/Tpj.2014.2  0.618
2014 Nicol MR, Fedoriw Y, Mathews M, Prince HM, Patterson KB, Geller E, Mollan K, Mathews S, Kroetz DL, Kashuba AD. Expression of six drug transporters in vaginal, cervical, and colorectal tissues: Implications for drug disposition in HIV prevention. Journal of Clinical Pharmacology. 54: 574-83. PMID 24343710 DOI: 10.1002/Jcph.248  0.342
2014 Chhibber A, Micheli J, Kroetz DL. Polymorphisms of Drug Transporters and Clinical Relevance Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition. 389-407. DOI: 10.1002/9781118705308.ch20  0.63
2013 Micheli JE, Chinn LW, Shugarts SB, Patel A, Martin JN, Bangsberg DR, Kroetz DL. Measuring the overall genetic component of nevirapine pharmacokinetics and the role of selected polymorphisms: towards addressing the missing heritability in pharmacogenetic phenotypes? Pharmacogenetics and Genomics. 23: 591-6. PMID 23982262 DOI: 10.1097/Fpc.0B013E32836533A5  0.722
2013 Markova SM, De Marco T, Bendjilali N, Kobashigawa EA, Mefford J, Sodhi J, Le H, Zhang C, Halladay J, Rettie AE, Khojasteh C, McGlothlin D, Wu AH, Hsueh WC, Witte JS, ... ... Kroetz DL, et al. Association of CYP2C9*2 with bosentan-induced liver injury. Clinical Pharmacology and Therapeutics. 94: 678-86. PMID 23863877 DOI: 10.1038/Clpt.2013.143  0.35
2013 Tamraz B, Fukushima H, Wolfe AR, Kaspera R, Totah RA, Floyd JS, Ma B, Chu C, Marciante KD, Heckbert SR, Psaty BM, Kroetz DL, Kwok PY. OATP1B1-related drug-drug and drug-gene interactions as potential risk factors for cerivastatin-induced rhabdomyolysis. Pharmacogenetics and Genomics. 23: 355-64. PMID 23652407 DOI: 10.1097/Fpc.0B013E3283620C3B  0.384
2013 Lewis LD, Miller AA, Owzar K, Bies RR, Markova S, Jiang C, Kroetz DL, Egorin MJ, McLeod HL, Ratain MJ. The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance). Pharmacogenetics and Genomics. 23: 29-33. PMID 23188068 DOI: 10.1097/Fpc.0B013E32835B16D8  0.361
2013 Nguyen TD, Markova S, Liu W, Gow JM, Baldwin RM, Habashian M, Relling MV, Ratain MJ, Kroetz DL. Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression. The Pharmacogenomics Journal. 13: 396-402. PMID 22664480 DOI: 10.1038/Tpj.2012.20  0.791
2013 Hertz DL, Owzar K, Halabi S, Kelly WK, Zembutsu H, Jiang C, Patel JN, Watson D, Shterev I, Kroetz DL, Friedman PN, Mahoney JF, Carducci MA, Kelley MJ, Small EJ, et al. A genome-wide association study (GWAS) of docetaxel-induced peripheral neuropathy in CALGB 90401 (Alliance). Journal of Clinical Oncology. 31: 11053-11053. DOI: 10.1200/Jco.2013.31.15_Suppl.11053  0.341
2013 Haenisch S, Chhibber A, Cascorbi I, Kroetz D. PP123—Target gene evaluation of two mirnas differently expressed in focal and non-focal brain tissue of therapy-resistant epilepsy patients Clinical Therapeutics. 35: e53-e54. DOI: 10.1016/J.Clinthera.2013.07.146  0.609
2012 Baldwin RM, Owzar K, Zembutsu H, Chhibber A, Kubo M, Jiang C, Watson D, Eclov RJ, Mefford J, McLeod HL, Friedman PN, Hudis CA, Winer EP, Jorgenson EM, Witte JS, ... ... Kroetz DL, et al. A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5099-109. PMID 22843789 DOI: 10.1158/1078-0432.Ccr-12-1590  0.765
2012 Matsson P, Yee SW, Markova S, Morrissey K, Jenkins G, Xuan J, Jorgenson E, Kroetz DL, Giacomini KM. Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping. The Pharmacogenomics Journal. 12: 214-26. PMID 21383772 DOI: 10.1038/Tpj.2011.8  0.453
2012 Wheeler HE, Gamazon ER, Njiaju UO, Wing C, Njoku C, Baldwin RM, Owzar K, Winer E, Hudis C, Shulman LN, Ratain MJ, Kroetz DL, Cox NJ, Dolan ME. Abstract 1881: Integration of cell line and Cancer and Leukemia Group B 40101 clinical trial genome-wide association analyses implicates multiple loci in paclitaxel-induced peripheral neuropathy Cancer Research. 72: 1881-1881. DOI: 10.1158/1538-7445.Am2012-1881  0.365
2011 Yoshino Y, Yuan B, Kaise T, Takeichi M, Tanaka S, Hirano T, Kroetz DL, Toyoda H. Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes. Toxicology and Applied Pharmacology. 257: 198-208. PMID 21945491 DOI: 10.1016/J.Taap.2011.09.006  0.339
2011 Kim MJ, Skewes-Cox P, Fukushima H, Hesselson S, Yee SW, Ramsey LB, Nguyen L, Eshragh JL, Castro RA, Wen CC, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Relling MV, ... ... Kroetz DL, et al. Functional characterization of liver enhancers that regulate drug-associated transporters. Clinical Pharmacology and Therapeutics. 89: 571-8. PMID 21368754 DOI: 10.1038/clpt.2010.353  0.311
2011 Hodges LM, Markova SM, Chinn LW, Gow JM, Kroetz DL, Klein TE, Altman RB. Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein). Pharmacogenetics and Genomics. 21: 152-61. PMID 20216335 DOI: 10.1097/Fpc.0B013E3283385A1C  0.771
2011 Kelly L, Fukushima H, Karchin R, Gow JM, Chinn LW, Pieper U, Segal MR, Kroetz DL, Sali A. Letter to the editor Protein Science. 20: 4-5. DOI: 10.1002/Pro.555  0.75
2010 Kelly L, Fukushima H, Karchin R, Gow JM, Chinn LW, Pieper U, Segal MR, Kroetz DL, Sali A. Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains. Protein Science : a Publication of the Protein Society. 19: 2110-21. PMID 20799350 DOI: 10.1002/Pro.491  0.784
2010 Ho RH, Leake BF, Kilkenny DM, Meyer Zu Schwabedissen HE, Glaeser H, Kroetz DL, Kim RB. Polymorphic variants in the human bile salt export pump (BSEP; ABCB11): functional characterization and interindividual variability. Pharmacogenetics and Genomics. 20: 45-57. PMID 20010382 DOI: 10.1097/Fpc.0B013E3283349Eb0  0.392
2010 Kroetz DL, Yee SW, Giacomini KM. The pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology. Clinical Pharmacology and Therapeutics. 87: 109-16. PMID 19940846 DOI: 10.1038/Clpt.2009.226  0.349
2010 Kroetz DL, Baldwin RM, Owzar K, Jiang C, Zembutsu H, Kubo M, Nakamura Y, Shulman LN, Ratain MJ. Inherited genetic variation in EPHA5, FGD4, and NRDG1 and paclitaxel (P)-induced peripheral neuropathy (PN): Results from a genome-wide association study (GWAS) in CALGB 40101. Journal of Clinical Oncology. 28: 3021-3021. DOI: 10.1200/Jco.2010.28.15_Suppl.3021  0.313
2009 Kroetz DL, Ahituv N, Burchard EG, Guo S, Sali A, Giacomini KM. Institutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy. Pharmacogenomics. 10: 1569-76. PMID 19842929 DOI: 10.2217/Pgs.09.119  0.331
2009 Hesselson SE, Matsson P, Shima JE, Fukushima H, Yee SW, Kobayashi Y, Gow JM, Ha C, Ma B, Poon A, Johns SJ, Stryke D, Castro RA, Tahara H, Choi JH, ... ... Kroetz DL, et al. Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation. Plos One. 4: e6942. PMID 19742321 DOI: 10.1371/Journal.Pone.0006942  0.788
2009 Innocenti F, Kroetz DL, Schuetz E, Dolan ME, Ramírez J, Relling M, Chen P, Das S, Rosner GL, Ratain MJ. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 2604-14. PMID 19349540 DOI: 10.1200/Jco.2008.20.6300  0.329
2009 Mayer F, Mayer N, Chinn L, Pinsonneault RL, Kroetz D, Bainton RJ. Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3538-50. PMID 19295159 DOI: 10.1523/Jneurosci.5564-08.2009  0.704
2009 Kroetz D. Involvement of ABC transporters in pharmacokinetics and toxicokinetics Toxicology Letters. 189: S17. DOI: 10.1016/J.Toxlet.2009.06.009  0.343
2009 Chinn LW, Kroetz DL. Genetic Polymorphisms in ABC Transporters Abc Transporters and Multidrug Resistance. 411-436. DOI: 10.1002/9780470495131.ch15  0.709
2008 McLeod HL, Owzar K, Kroetz D, Innocenti F, Das S, Friedman P, Giacomini K, Goldberg RM, Venook AP, Ratain MJ. Cellular transporter pharmacogenetics in metastatic colorectal cancer: Initial analysis of C80203. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 3513. PMID 27949752 DOI: 10.1200/Jco.2008.26.15_Suppl.3513  0.328
2008 Byakika-Tusiime J, Chinn LW, Oyugi JH, Obua C, Bangsberg DR, Kroetz DL. Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adults. Plos One. 3: e3981. PMID 19096711 DOI: 10.1371/Journal.Pone.0003981  0.672
2008 Fife KL, Liu Y, Schmelzer KR, Tsai HJ, Kim IH, Morisseau C, Hammock BD, Kroetz DL. Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation. The Journal of Pharmacology and Experimental Therapeutics. 327: 707-15. PMID 18815352 DOI: 10.1124/Jpet.108.142398  0.752
2008 Abla N, Chinn LW, Nakamura T, Liu L, Huang CC, Johns SJ, Kawamoto M, Stryke D, Taylor TR, Ferrin TE, Giacomini KM, Kroetz DL. The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene. The Journal of Pharmacology and Experimental Therapeutics. 325: 859-68. PMID 18364470 DOI: 10.1124/Jpet.108.136523  0.748
2008 Gow JM, Hodges LM, Chinn LW, Kroetz DL. Substrate-dependent effects of human ABCB1 coding polymorphisms. The Journal of Pharmacology and Experimental Therapeutics. 325: 435-42. PMID 18287207 DOI: 10.1124/Jpet.107.135194  0.792
2008 Gow JM, Chinn LW, Kroetz DL. The effects of ABCB1 3'-untranslated region variants on mRNA stability. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 10-5. PMID 17940136 DOI: 10.1124/Dmd.107.017087  0.776
2007 Chinn LW, Gow JM, Tse MM, Becker SL, Kroetz DL. Interindividual variability in the effect of atazanavir and saquinavir on the expression of lymphocyte P-glycoprotein. The Journal of Antimicrobial Chemotherapy. 60: 61-7. PMID 17510066 DOI: 10.1093/Jac/Dkm135  0.783
2007 Soranzo N, Kelly L, Martinian L, Burley MW, Thom M, Sali A, Kroetz DL, Goldstein DB, Sisodiya SM. Lack of support for a role for RLIP76 (RALBP1) in response to treatment or predisposition to epilepsy. Epilepsia. 48: 674-83. PMID 17437410 DOI: 10.1111/J.1528-1167.2007.00926.X  0.371
2007 Ng VY, Huang Y, Reddy LM, Falck JR, Lin ET, Kroetz DL. Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 1126-34. PMID 17431031 DOI: 10.1124/Dmd.106.013839  0.355
2007 Jeong H, Herskowitz I, Kroetz DL, Rine J. Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay. Plos Genetics. 3: e39. PMID 17352537 DOI: 10.1371/Journal.Pgen.0030039  0.444
2007 Giacomini KM, Brett CM, Altman RB, Benowitz NL, Dolan ME, Flockhart DA, Johnson JA, Hayes DF, Klein T, Krauss RM, Kroetz DL, McLeod HL, Nguyen AT, Ratain MJ, Relling MV, et al. The pharmacogenetics research network: from SNP discovery to clinical drug response. Clinical Pharmacology and Therapeutics. 81: 328-45. PMID 17339863 DOI: 10.1038/Sj.Clpt.6100087  0.316
2007 Chinn LW, Kroetz DL. ABCB1 pharmacogenetics: progress, pitfalls, and promise. Clinical Pharmacology and Therapeutics. 81: 265-9. PMID 17259950 DOI: 10.1038/Sj.Clpt.6100052  0.736
2007 de Jong FA, Scott-Horton TJ, Kroetz DL, McLeod HL, Friberg LE, Mathijssen RH, Verweij J, Marsh S, Sparreboom A. Irinotecan-induced diarrhea: functional significance of the polymorphic ABCC2 transporter protein. Clinical Pharmacology and Therapeutics. 81: 42-9. PMID 17185998 DOI: 10.1038/Sj.Clpt.6100019  0.38
2006 Kroetz DL. Role for drug transporters beyond tumor resistance: hepatic functional imaging and genotyping of multidrug resistance transporters for the prediction of irinotecan toxicity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 4225-7. PMID 16895999 DOI: 10.1200/Jco.2006.07.2355  0.396
2006 Badagnani I, Sorani M, Edwards RH, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson EJ, Taylor T, Chan W, De La Cruz M, Ferrin TE, Burchard EG, ... ... Kroetz DL, et al. PharmGKB submission update: VI. PMT submissions of genetic variations in neurotransmitter transporters (SLC6, SLC17, and SLC18) to the PharmGKB network. Pharmacological Reviews. 58: 5-6. PMID 16507879 DOI: 10.1124/Pr.58.1.3  0.365
2006 Shu Y, Urban TJ, Leabman MK, Fujita T, Erdman AR, Lagpacan LL, Brown C, Castro RA, Huang CC, Stryke D, Kawamoto M, Johns SJ, Taylor TR, Chan W, De La Cruz M, ... ... Kroetz DL, et al. PharmGKB submission update: V. PMT submissions of genetic variation in SLC22 family transporters. Pharmacological Reviews. 58: 3-4. PMID 16507878 DOI: 10.1124/Pr.58.1.2  0.362
2006 Nguyen TD, Gow JM, Chinn LW, Kelly L, Jeong H, Huang CC, Stryke D, Kawamoto M, Johns SJ, Carlson E, Taylor T, Ferrin TE, Sali A, Giacomini KM, Kroetz DL. PharmGKB submission update: IV. PMT submissions of genetic variations in ATP-Binding cassette transporters to the PharmGKB network. Pharmacological Reviews. 58: 1-2. PMID 16507877 DOI: 10.1124/Pr.58.1.1  0.772
2006 Yu Z, Ng VY, Su P, Engler MM, Engler MB, Huang Y, Lin E, Kroetz DL. Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. The Journal of Pharmacology and Experimental Therapeutics. 317: 732-8. PMID 16421287 DOI: 10.1124/Jpet.105.098558  0.522
2006 Kroetz DL, Liu W, Nguyen TD, Zwecker BM, Ramirez J, Innocenti F, Ratain MJ. 1249G>A polymorphism of ABCC2 (MRP2) is associated with altered gene expression in human liver Journal of Clinical Oncology. 24: 13072-13072. DOI: 10.1200/Jco.2006.24.18_Suppl.13072  0.383
2006 DEJONG F, SCOTTHORTON T, KROETZ D, MCLEOD H, FRIBERG L, MATHIJSSEN R, VERWEIJ J, SPARREBOOM A, MARSH S. PII-20Irinotecan (CPT-11) related diarrhea: Functional significance of the polymorphic ABCC2 transporter protein Clinical Pharmacology & Therapeutics. 79: P41-P41. DOI: 10.1016/J.Clpt.2005.12.145  0.365
2006 CHINN L, GOW J, BECKER S, TSE M, KROETZ D. OII-B-4Effect of HIV protease inhibitor administration on ABC transporter expression in human peripheral blood mononuclear cells (PBMCS) Clinical Pharmacology & Therapeutics. 79: P6-P6. DOI: 10.1016/J.Clpt.2005.12.017  0.766
2005 Innocenti F, Undevia SD, Rosner GL, Xiao L, Liu W, Chen P, Das S, Ramirez J, Kroetz DL, Ratain MJ. Irinotecan (CPT-11) pharmacokinetics (PK) and neutropenia: interaction among UGT1A1 and transporter genes. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 2006. PMID 27946805 DOI: 10.1200/Jco.2005.23.16_Suppl.2006  0.406
2005 Wang D, Johnson AD, Papp AC, Kroetz DL, Sadée W. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenetics and Genomics. 15: 693-704. PMID 16141795 DOI: 10.1097/01.Fpc.0000178311.02878.83  0.332
2005 KROETZ D, NGUYEN T, GIANG T, HODGES L, CASTRO R, LIN E, BRETT C, SWAN G. Heritability of digoxin pharmacokinetics Clinical Pharmacology & Therapeutics. 77: P21-P21. DOI: 10.1016/J.Clpt.2004.11.083  0.349
2004 Pauli-Magnus C, Kroetz DL. Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1). Pharmaceutical Research. 21: 904-13. PMID 15212152 DOI: 10.1023/B:Pham.0000029276.21063.0B  0.45
2004 Yu Z, Davis BB, Morisseau C, Hammock BD, Olson JL, Kroetz DL, Weiss RH. Vascular localization of soluble epoxide hydrolase in the human kidney. American Journal of Physiology. Renal Physiology. 286: F720-6. PMID 14665429 DOI: 10.1152/Ajprenal.00165.2003  0.526
2004 Xu F, Falck JR, Ortiz de Montellano PR, Kroetz DL. Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes. The Journal of Pharmacology and Experimental Therapeutics. 308: 887-95. PMID 14634044 DOI: 10.1124/Jpet.103.059626  0.303
2004 Innocenti F, Undevia SD, Chen PX, Das S, Ramirez J, Dolan ME, Relling MV, Kroetz DL, Ratain MJ. Pharmacogenetic analysis of interindividual irinotecan (CPT-11) pharmacokinetic (PK) variability: Evidence for a functional variant of ABCC2 Journal of Clinical Oncology. 22: 2010-2010. DOI: 10.1200/Jco.2004.22.90140.2010  0.352
2003 Pauli-Magnus C, Feiner J, Brett C, Lin E, Kroetz DL. No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects. Clinical Pharmacology and Therapeutics. 74: 487-98. PMID 14586389 DOI: 10.1016/S0009-9236(03)00234-0  0.414
2003 Kroetz DL, Pauli-Magnus C, Hodges LM, Huang CC, Kawamoto M, Johns SJ, Stryke D, Ferrin TE, DeYoung J, Taylor T, Carlson EJ, Herskowitz I, Giacomini KM, Clark AG. Sequence diversity and haplotype structure in the human ABCB1 (MDR1, multidrug resistance transporter) gene. Pharmacogenetics. 13: 481-94. PMID 12893986 DOI: 10.1097/00008571-200308000-00006  0.402
2003 Leabman MK, Huang CC, DeYoung J, Carlson EJ, Taylor TR, de la Cruz M, Johns SJ, Stryke D, Kawamoto M, Urban TJ, Kroetz DL, Ferrin TE, Clark AG, Risch N, Herskowitz I, et al. Natural variation in human membrane transporter genes reveals evolutionary and functional constraints. Proceedings of the National Academy of Sciences of the United States of America. 100: 5896-901. PMID 12719533 DOI: 10.1073/Pnas.0730857100  0.376
2003 Nguyen T, Huang C, Kawamoto M, Carlson E, Herskowitz I, Giacomini K, Kroetz D. Genetic variation and haplotype structure of human multidrug resistance-associated protein 2(MRP2) Clinical Pharmacology & Therapeutics. 73: P59-P59. DOI: 10.1016/S0009-9236(03)90573-X  0.528
2003 Chinn L, Kroetz D. Altered P-Glycoprotein immunoreactivity but normal function in human peripheral blood mononuclear cells (PBMCS) Clinical Pharmacology & Therapeutics. 73: P58-P58. DOI: 10.1016/S0009-9236(03)90572-8  0.698
2003 Hodges L, Lacayo C, Chinn L, Ho C, Lillehammer T, Pauli-Magnus C, Kroetz D. Ala893ser variant has no effect on p-glycoprotein (P-GP) function. Clinical Pharmacology & Therapeutics. 73: P13-P13. DOI: 10.1016/S0009-9236(03)90404-8  0.705
2002 Ring HZ, Kroetz DL. Candidate gene approach for pharmacogenetic studies. Pharmacogenomics. 3: 47-56. PMID 11966402 DOI: 10.1517/14622416.3.1.47  0.352
2000 Yu Z, Xu F, Huse LM, Morisseau C, Draper AJ, Newman JW, Parker C, Graham L, Engler MM, Hammock BD, Zeldin DC, Kroetz DL. Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids. Circulation Research. 87: 992-8. PMID 11090543 DOI: 10.1161/01.Res.87.11.992  0.525
2000 Spiegelstein O, Kroetz DL, Levy RH, Yagen B, Hurst SI, Levi M, Haj-Yehia A, Bialer M. Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid. Pharmaceutical Research. 17: 216-21. PMID 10751038 DOI: 10.1023/A:1007577600088  0.453
1999 Engler MM, Engler MB, Goodfriend TL, Ball DL, Yu Z, Su P, Kroetz DL. Docosahexaenoic acid is an antihypertensive nutrient that affects aldosterone production in SHR. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 221: 32-8. PMID 10320629 DOI: 10.1046/J.1525-1373.1999.D01-51.X  0.513
1997 Kroetz DL, Huse LM, Thuresson A, Grillo MP. Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney. Molecular Pharmacology. 52: 362-72. PMID 9281597 DOI: 10.1124/Mol.52.3.362  0.302
1994 Kerr BM, Thummel KE, Wurden CJ, Klein SM, Kroetz DL, Gonzalez FJ, Levy RH. Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation. Biochemical Pharmacology. 47: 1969-79. PMID 8010982 DOI: 10.1016/0006-2952(94)90071-X  0.52
1993 Kroetz DL, Kerr BM, McFarland LV, Loiseau P, Wilensky AJ, Levy RH. Measurement of in vivo microsomal epoxide hydrolase activity in white subjects. Clinical Pharmacology and Therapeutics. 53: 306-15. PMID 8453849 DOI: 10.1038/Clpt.1993.26  0.479
1993 Kroetz DL, Loiseau P, Guyot M, Levy RH. In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide. Clinical Pharmacology and Therapeutics. 54: 485-97. PMID 8222491 DOI: 10.1038/Clpt.1993.180  0.473
1993 Pisani F, Haj-Yehia A, Fazio A, Artesi C, Oteri G, Perucca E, Kroetz DL, Levy RH, Bialer M. Carbamazepine-valnoctamide interaction in epileptic patients: in vitro/in vivo correlation. Epilepsia. 34: 954-9. PMID 8104783 DOI: 10.1111/J.1528-1157.1993.Tb02117.X  0.464
1993 Pisani F, Haj-Yehia A, Fazio A, Artesi C, Oteri G, Perucca E, Kroetz DL, Levy RH, Bialer M. Interaction of Carbamazepine with Valnoctamide: Data 'in vitro' and in patients with epilepsy | INTERAZIONE DELLA CARBAMAZEPINA CON LA VALNOCTAMIDE: DATI 'IN VITRO' ED IN PAZIENTI CON EPILESSIA Bollettino - Lega Italiana Contro L'Epilessia. 159.  0.36
Show low-probability matches.