☰

Eric J. Toone

Affiliations: 
Chemistry Duke University, Durham, NC 
Area:
biocatalysis/applied enzymology, ligand binding and the activity of water, and the synthesis of novel donors of nitric oxide
Website:
http://fds.duke.edu/db/aas/Chemistry/faculty/eric.toone
Google:
"Eric Toone"
Bio:

http://www.chem.duke.edu/~toone/labgroup/toone.html
http://arpa-e.energy.gov/About/Team/DrEricToone.aspx

Mean distance: 6.66
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Parents

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J. Bryan Jones grad student 1988 University of Toronto
 (The development of an active site model for pig liver esterase)
George M. Whitesides post-doc 1988-1990 Harvard

Children

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Nikki F. Burkhalter grad student 2000 Duke
Charles A. DiTusa grad student 2000 Duke
Jayme B. Corbell grad student 2002 Duke
Joseph J. Lundquist grad student 2002 Duke
Joseph D. Mannion grad student 2002 Duke
Steven C. Powell grad student 2002 Duke
Nathan J. Wymer grad student 2002 Duke
Harinath Chakrapani grad student 2005
Bo Y. Choi grad student 2005 Duke
Phillip W. Snyder grad student 2005 Duke
Yu Du grad student 2006 Duke
David M. Gooden grad student 2006 Duke
John A. Hatten grad student 2006 Duke
Corey P. Causey grad student 2007 Duke
Andrea E. Luteran grad student 2007 Duke
Jim Parise grad student 2007 Duke
Matthew J. Walters grad student 2008 Duke
Alexander A. Shestopalov grad student 2009 Duke
David A. Carlson grad student 2010 Duke
Briana N. Vogen grad student 2010 Duke
Erin M. Wilfong grad student 2010 Duke
Carleen M. Bowers grad student 2012 Duke
Allison A. Schmitt grad student 2012 Duke

Collaborators

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BETA: Related publications

Publications

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Zhao J, Cochrane CS, Najeeb J, et al. (2023) Preclinical safety and efficacy characterization of an LpxC inhibitor against Gram-negative pathogens. Science Translational Medicine. 15: eadf5668
Lee CJ, Liang X, Wu Q, et al. (2016) Drug design from the cryptic inhibitor envelope. Nature Communications. 7: 10638
King JR, Bowers CM, Toone EJ. (2015) Specific binding at the cellulose binding module-cellulose interface observed by force spectroscopy. Langmuir : the Acs Journal of Surfaces and Colloids. 31: 3431-40
Xia W, Gooden D, Liu L, et al. (2014) Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis. Plos One. 9: e88983
Lee CJ, Liang X, Gopalaswamy R, et al. (2014) Structural basis of the promiscuous inhibitor susceptibility of Escherichia coli LpxC. Acs Chemical Biology. 9: 237-46
Sund JB, Causey CP, Wolter SD, et al. (2014) Diamond surface functionalization with biomimicry - Amine surface tether and thiol moiety for electrochemical sensors Applied Surface Science. 301: 293-299
Bowers CM, Zhang M, Lyubarskaya Y, et al. (2014) Organic Electronics: Structural Modifications in Bilayered Molecular Systems Lead to Predictable Changes in Their Electronic Properties (Adv. Mater. Interfaces 2/2014) Advanced Materials Interfaces. 1
Bowers CM, Zhang M, Lyubarskaya Y, et al. (2014) Structural Modifications in Bilayered Molecular Systems Lead to Predictable Changes in Their Electronic Properties Advanced Materials Interfaces. 1
Liang X, Lee CJ, Zhao J, et al. (2013) Synthesis, structure, and antibiotic activity of aryl-substituted LpxC inhibitors. Journal of Medicinal Chemistry. 56: 6954-66
Bowers CM, Carlson DA, Rivera M, et al. (2013) Effect of compressive force on unbinding specific protein-ligand complexes with force spectroscopy. The Journal of Physical Chemistry. B. 117: 4755-62
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