| Year |
Citation |
Score |
| 2023 |
Sakthivel R, Criado-Marrero M, Barroso D, Braga IM, Bolen M, Rubinovich U, Hery GP, Grudny MM, Koren J, Prokop S, Febo M, Abisambra JF. Fixed Time-Point Analysis Reveals Repetitive Mild Traumatic Brain Injury Effects on Resting State Functional Magnetic Resonance Imaging Connectivity and Neuro-Spatial Protein Profiles. Journal of Neurotrauma. PMID 37051703 DOI: 10.1089/neu.2022.0464 |
0.637 |
|
| 2021 |
Cloyd RA, Koren J, Abisambra JF, Smith BN. Effects of altered tau expression on dentate granule cell excitability in mice. Experimental Neurology. 343: 113766. PMID 34029610 DOI: 10.1016/j.expneurol.2021.113766 |
0.703 |
|
| 2021 |
Koren SA, Hamm MJ, Cloyd R, Fontaine SN, Chishti E, Lanzillotta C, Rodriguez-Rivera J, Ingram A, Bell M, Galvis-Escobar SM, Zulia N, Di Domenico F, Duong D, Seyfried NT, Powell D, ... ... Koren J, et al. Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy. International Journal of Molecular Sciences. 22. PMID 33530349 DOI: 10.3390/ijms22031186 |
0.69 |
|
| 2020 |
Koren J, Blagg BSJ. The Right Tool for the Job: An Overview of Hsp90 Inhibitors. Advances in Experimental Medicine and Biology. 1243: 135-146. PMID 32297216 DOI: 10.1007/978-3-030-40204-4_9 |
0.333 |
|
| 2019 |
Darling AL, Breydo L, Rivas EG, Gebru NT, Zheng D, Baker JD, Blair LJ, Dickey CA, Koren J, Uversky VN. Repeated repeat problems: Combinatorial effect of C9orf72-derived dipeptide repeat proteins. International Journal of Biological Macromolecules. PMID 30639592 DOI: 10.1016/J.Ijbiomac.2019.01.035 |
0.726 |
|
| 2018 |
Sabbagh JJ, Cordova RA, Zheng D, Criado-Marrero M, Lemus A, Li P, Baker JD, Nordhues BA, Darling AL, Martinez-Licha C, Rutz DA, Patel S, Buchner J, Leahy JW, Koren J, et al. Targeting the FKBP51/GR/Hsp90 complex to identify functionally relevant treatments for depression and PTSD. Acs Chemical Biology. PMID 29893552 DOI: 10.1021/Acschembio.8B00454 |
0.752 |
|
| 2018 |
Huard DJ, Crowley VM, Du Y, Cordova RA, Sun Z, Tomlin MO, Dickey CA, Koren J, Blair L, Fu H, Blagg BSJ, Lieberman RL. Trifunctional high-throughput screen identifies promising scaffold to inhibit Grp94 and treat myocilin-associated glaucoma. Acs Chemical Biology. PMID 29402077 DOI: 10.1021/Acschembio.7B01083 |
0.755 |
|
| 2018 |
Criado-Marrero M, Rein T, Binder EB, Porter JT, Koren J, Blair LJ. Hsp90 and FKBP51: complex regulators of psychiatric diseases. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29203717 DOI: 10.1098/Rstb.2016.0532 |
0.691 |
|
| 2017 |
Shelton LB, Koren J, Blair LJ. Imbalances in the Hsp90 Chaperone Machinery: Implications for Tauopathies. Frontiers in Neuroscience. 11: 724. PMID 29311797 DOI: 10.3389/Fnins.2017.00724 |
0.776 |
|
| 2017 |
Stothert AR, Suntharalingam A, Tang X, Crowley VM, Mishra SJ, Webster JM, Nordhues BA, Huard DJE, Passaglia CL, Lieberman RL, Blagg BSJ, Blair LJ, Koren J, Dickey CA. Isoform-selective Hsp90 inhibition rescues model of hereditary open-angle glaucoma. Scientific Reports. 7: 17951. PMID 29263415 DOI: 10.1038/S41598-017-18344-4 |
0.768 |
|
| 2017 |
Shelton LB, Baker JD, Zheng D, Sullivan LE, Solanki PK, Webster JM, Sun Z, Sabbagh JJ, Nordhues BA, Koren J, Ghosh S, Blagg BSJ, Blair LJ, Dickey CA. Hsp90 activator Aha1 drives production of pathological tau aggregates. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827321 DOI: 10.1073/Pnas.1707039114 |
0.824 |
|
| 2017 |
Baker JD, Shelton LB, Zheng D, Favretto F, Nordhues BA, Darling A, Sullivan LE, Sun Z, Solanki PK, Martin MD, Suntharalingam A, Sabbagh JJ, Becker S, Mandelkow E, Uversky VN, ... ... Koren J, et al. Human cyclophilin 40 unravels neurotoxic amyloids. Plos Biology. 15: e2001336. PMID 28654636 DOI: 10.1371/Journal.Pbio.2001336 |
0.794 |
|
| 2017 |
Baker JD, Shelton LB, Zheng D, Blair LJ, Koren J, Zweckstetter M, Dickey CA. [P2-168]: PPID CONTROLS TOXIC AMYLOID FORMATION THROUGH PROLINE ISOMERIZATION Alzheimer's & Dementia. 13: P671-P671. DOI: 10.1016/J.Jalz.2017.06.819 |
0.595 |
|
| 2017 |
Baker JD, Breydo L, Dickey CA, Blair LJ, Koren J. [P4-103]: PROLINE ISOMERIZATION CONTROLS TOXIC AMYLOID FORMATION Alzheimer's & Dementia. 13: P1297-P1297. DOI: 10.1016/J.Jalz.2017.06.1969 |
0.595 |
|
| 2016 |
Rodina A, Wang T, Yan P, Gomes ED, Dunphy MP, Pillarsetty N, Koren J, Gerecitano JF, Taldone T, Zong H, Caldas-Lopes E, Alpaugh M, Corben A, Riolo M, Beattie B, et al. The epichaperome is an integrated chaperome network that facilitates tumour survival. Nature. PMID 27706135 DOI: 10.1038/Nature19807 |
0.368 |
|
| 2015 |
Koren J, Xu C, Rodina A, Shrestha L, Taldone T, Chiosis G. Abstract 1740: Allosteric Hsp70-family inhibitors as targeted anticancer therapeutics Cancer Research. 75: 1740-1740. DOI: 10.1158/1538-7445.Am2015-1740 |
0.416 |
|
| 2015 |
Rodina AA, Taldone T, Kang Y, Patel P, Koren J, Yan P, Gomes ED, Yang C, Patel M, Shrestha L, Ochiana S, Maharaj R, Gozman A, Cox M, Erdjument-Bromage H, et al. Abstract 1733: Development of chemical tools to study the endogenous Hsp70 interactome in malignant cells Cancer Research. 75: 1733-1733. DOI: 10.1158/1538-7445.Am2015-1733 |
0.422 |
|
| 2015 |
Inda C, Koren J, Boalander A, Panchal P, Gandu S, Chiosis G. P3-327: Hsp90 inhibition rescues behavioral deficits and reduces tau phosphorylation in ps19 mice model for Alzheimer's disease (AD) Alzheimer's & Dementia. 11: P764-P764. DOI: 10.1016/J.Jalz.2015.06.1701 |
0.471 |
|
| 2015 |
Koren J, Inda C, Chiosis G. P3-326: Blood-brain barrier permeable hsp90 inhibitor reduces soluble tau burden and rescues tau-dependent phenotype in a mouse model of tau accumulation Alzheimer's & Dementia. 11: P763-P764. DOI: 10.1016/J.Jalz.2015.06.1700 |
0.495 |
|
| 2014 |
Azoitei N, Diepold K, Brunner C, Rouhi A, Genze F, Becher A, Kestler H, van Lint J, Chiosis G, Koren J, Fröhling S, Scholl C, Seufferlein T. HSP90 supports tumor growth and angiogenesis through PRKD2 protein stabilization. Cancer Research. 74: 7125-36. PMID 25297628 DOI: 10.1158/0008-5472.Can-14-1017 |
0.333 |
|
| 2014 |
Rodina A, Taldone T, Kang Y, Patel PD, Koren J, Yan P, DaGama Gomes EM, Yang C, Patel MR, Shrestha L, Ochiana SO, Santarossa C, Maharaj R, Gozman A, Cox MB, et al. Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer. Acs Chemical Biology. 9: 1698-705. PMID 24934503 DOI: 10.1021/Cb500256U |
0.312 |
|
| 2014 |
Jhaveri K, Ochiana SO, Dunphy MP, Gerecitano JF, Corben AD, Peter RI, Janjigian YY, Gomes-DaGama EM, Koren J, Modi S, Chiosis G. Heat shock protein 90 inhibitors in the treatment of cancer: current status and future directions. Expert Opinion On Investigational Drugs. 23: 611-28. PMID 24669860 DOI: 10.1517/13543784.2014.902442 |
0.396 |
|
| 2014 |
Carman A, Kishinevsky S, Koren J, Luo W, Chiosis G. Regulatory chaperone complexes in neurodegenerative diseases: a perspective on therapeutic intervention. Current Alzheimer Research. 11: 59-68. PMID 24251390 DOI: 10.2174/1567205010666131119233044 |
0.478 |
|
| 2013 |
Carman A, Kishinevsky S, Koren J, Lou W, Chiosis G. Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention. Journal of Alzheimer's Disease & Parkinsonism. 2013. PMID 25258700 DOI: 10.4172/2161-0460.S10-007 |
0.47 |
|
| 2013 |
O'Leary JC, Zhang B, Koren J, Blair L, Dickey CA. The role of FKBP5 in mood disorders: action of FKBP5 on steroid hormone receptors leads to questions about its evolutionary importance. Cns & Neurological Disorders Drug Targets. 12: 1157-62. PMID 24040820 DOI: 10.2174/187152731131200121 |
0.714 |
|
| 2013 |
Jinwal UK, Koren J, Dickey CA. Reconstructing the Hsp90/Tau Machine. Current Enzyme Inhibition. 9: 41-45. PMID 23798910 DOI: 10.2174/1573408011309010006 |
0.723 |
|
| 2013 |
Abisambra J, Jinwal UK, Miyata Y, Rogers J, Blair L, Li X, Seguin SP, Wang L, Jin Y, Bacon J, Brady S, Cockman M, Guidi C, Zhang J, Koren J, et al. Allosteric heat shock protein 70 inhibitors rapidly rescue synaptic plasticity deficits by reducing aberrant tau. Biological Psychiatry. 74: 367-74. PMID 23607970 DOI: 10.1016/J.Biopsych.2013.02.027 |
0.826 |
|
| 2013 |
Koren J, Inda MC, Riolo M, Uddin M, Alonso-Sabadell R, Chiosis G. P1-402: Blood-brain-barrier-permeable Hsp90 inhibitor reduces soluble tau burden in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 9: P305-P305. DOI: 10.1016/J.Jalz.2013.05.630 |
0.459 |
|
| 2012 |
Suntharalingam A, Abisambra JF, O'Leary JC, Koren J, Zhang B, Joe MK, Blair LJ, Hill SE, Jinwal UK, Cockman M, Duerfeldt AS, Tomarev S, Blagg BS, Lieberman RL, Dickey CA. Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism. The Journal of Biological Chemistry. 287: 40661-9. PMID 23035116 DOI: 10.1074/Jbc.M112.384800 |
0.787 |
|
| 2012 |
Koren J, Miyata Y, Kiray J, O'Leary JC, Nguyen L, Guo J, Blair LJ, Li X, Li X, Jinwal UK, Cheng JQ, Gestwicki JE, Dickey CA. Rhodacyanine derivative selectively targets cancer cells and overcomes tamoxifen resistance. Plos One. 7: e35566. PMID 22563386 DOI: 10.1371/Journal.Pone.0035566 |
0.713 |
|
| 2012 |
Koren J, Miyata Y, Kiray J, O'Leary JC, Nguyen L, Guo J, Blair LJ, Li X, Jinwal UK, Cheng JQ, Gestwicki JE, Dickey CA. Correction: Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance Plos One. 7. DOI: 10.1371/Annotation/7493E5D2-4C1A-43Eb-A83F-16814861Ff13 |
0.528 |
|
| 2011 |
Abisambra JF, Jinwal UK, Jones JR, Blair LJ, Koren J, Dickey CA. Exploiting the diversity of the heat-shock protein family for primary and secondary tauopathy therapeutics. Current Neuropharmacology. 9: 623-31. PMID 22654720 DOI: 10.2174/157015911798376226 |
0.828 |
|
| 2011 |
Voss K, Koren J, Dickey CA. The earliest tau dysfunction in Alzheimer's disease? Tau phosphorylated at s422 as a toxic seed. The American Journal of Pathology. 179: 2148-51. PMID 21964186 DOI: 10.1016/J.Ajpath.2011.08.020 |
0.685 |
|
| 2011 |
Miyata Y, Koren J, Kiray J, Dickey CA, Gestwicki JE. Molecular chaperones and regulation of tau quality control: strategies for drug discovery in tauopathies. Future Medicinal Chemistry. 3: 1523-37. PMID 21882945 DOI: 10.4155/Fmc.11.88 |
0.718 |
|
| 2011 |
O'Leary JC, Koren J, Dickey CA. Neuronal life span versus health span: principles of natural selection at work in the degenerating brain. Journal of Molecular Neuroscience : Mn. 45: 467-72. PMID 21559875 DOI: 10.1007/S12031-011-9540-4 |
0.637 |
|
| 2011 |
Koren J, Jinwal UK, Davey Z, Kiray J, Arulselvam K, Dickey CA. Bending tau into shape: the emerging role of peptidyl-prolyl isomerases in tauopathies. Molecular Neurobiology. 44: 65-70. PMID 21523562 DOI: 10.1007/S12035-011-8182-4 |
0.712 |
|
| 2011 |
Jinwal UK, Trotter JH, Abisambra JF, Koren J, Lawson LY, Vestal GD, O'Leary JC, Johnson AG, Jin Y, Jones JR, Li Q, Weeber EJ, Dickey CA. The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics. The Journal of Biological Chemistry. 286: 16976-83. PMID 21367866 DOI: 10.1074/Jbc.M110.182493 |
0.815 |
|
| 2011 |
Jones JR, Lebar MD, Jinwal UK, Abisambra JF, Koren J, Blair L, O'Leary JC, Davey Z, Trotter J, Johnson AG, Weeber E, Eckman CB, Baker BJ, Dickey CA. The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau. Journal of Natural Products. 74: 38-44. PMID 21141876 DOI: 10.1021/Np100572Z |
0.823 |
|
| 2011 |
Koren J, Miyata Y, Kiray J, Guo J, Gestwicki J, Cheng JQ, Dickey C. Abstract 2094: Hsp70 inhibitors overcome tamoxifen resistance, in cell culture model Cancer Research. 71: 2094-2094. DOI: 10.1158/1538-7445.Am2011-2094 |
0.609 |
|
| 2011 |
Abisambra J, Cannon A, O'Leary J, Brady S, Espinosa A, Jinwal U, Koren J, Blair L, Lewis J, Dickey C. O4-04-08: Neuronal tau-specific stress induction of molecular chaperones: The failure of a coping mechanism Alzheimer's & Dementia. 7: S691-S691. DOI: 10.1016/J.Jalz.2011.05.1996 |
0.738 |
|
| 2011 |
Jinwal U, Abisambra J, Koren J, O'Leary J, Blair L, Hill S, Trotter J, Mushcol M, Weeber E, Gestwicki J, Dickey C. P3-124: Exploiting the diversity of the chaperone repertoire to treat tauopathies Alzheimer's & Dementia. 7: S554-S554. DOI: 10.1016/J.Jalz.2011.05.1565 |
0.721 |
|
| 2010 |
Abisambra JF, Blair LJ, Hill SE, Jones JR, Kraft C, Rogers J, Koren J, Jinwal UK, Lawson L, Johnson AG, Wilcock D, O'Leary JC, Jansen-West K, Muschol M, Golde TE, et al. Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15374-82. PMID 21084594 DOI: 10.1523/Jneurosci.3155-10.2010 |
0.829 |
|
| 2010 |
O'Leary JC, Li Q, Marinec P, Blair LJ, Congdon EE, Johnson AG, Jinwal UK, Koren J, Jones JR, Kraft C, Peters M, Abisambra JF, Duff KE, Weeber EJ, Gestwicki JE, et al. Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden. Molecular Neurodegeneration. 5: 45. PMID 21040568 DOI: 10.1186/1750-1326-5-45 |
0.812 |
|
| 2010 |
Lebson L, Nash K, Kamath S, Herber D, Carty N, Lee DC, Li Q, Szekeres K, Jinwal U, Koren J, Dickey CA, Gottschall PE, Morgan D, Gordon MN. Trafficking CD11b-positive blood cells deliver therapeutic genes to the brain of amyloid-depositing transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9651-8. PMID 20660248 DOI: 10.1523/Jneurosci.0329-10.2010 |
0.698 |
|
| 2010 |
Jinwal UK, Koren J, O'Leary JC, Jones JR, Abisambra JF, Dickey CA. Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative Diseases. Molecular and Cellular Pharmacology. 2: 43-46. PMID 20523917 DOI: 10.4255/mcpharmacol.10.06 |
0.813 |
|
| 2010 |
Jinwal UK, O'Leary JC, Borysov SI, Jones JR, Li Q, Koren J, Abisambra JF, Vestal GD, Lawson LY, Johnson AG, Blair LJ, Jin Y, Miyata Y, Gestwicki JE, Dickey CA. Hsc70 rapidly engages tau after microtubule destabilization. The Journal of Biological Chemistry. 285: 16798-805. PMID 20308058 DOI: 10.1074/Jbc.M110.113753 |
0.825 |
|
| 2010 |
Jinwal UK, Koren J, Borysov SI, Schmid AB, Abisambra JF, Blair LJ, Johnson AG, Jones JR, Shults CL, O'Leary JC, Jin Y, Buchner J, Cox MB, Dickey CA. The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 591-9. PMID 20071522 DOI: 10.1523/Jneurosci.4815-09.2010 |
0.837 |
|
| 2010 |
Koren J, Jinwal UK, Jin Y, O'Leary J, Jones JR, Johnson AG, Blair LJ, Abisambra JF, Chang L, Miyata Y, Cheng AM, Guo J, Cheng JQ, Gestwicki JE, Dickey CA. Facilitating Akt clearance via manipulation of Hsp70 activity and levels. The Journal of Biological Chemistry. 285: 2498-505. PMID 19889640 DOI: 10.1074/Jbc.M109.057208 |
0.793 |
|
| 2010 |
Dickey CA, O'Leary JC, Borysov S, Koren J, Jones J, Lawson L, Blair L, Jin Y, Lawson L, Abisambra JF, Li Q, Jinwal UK. P1-370: The early involvement of chaperones in tau pathogenesis Alzheimer's & Dementia. 6: S280-S280. DOI: 10.1016/J.Jalz.2010.05.924 |
0.769 |
|
| 2010 |
Abisambra JF, Blair LJ, Jones JR, Kraft C, Hill S, Rogers J, Koren J, Jinwal UK, Lawson L, Johnson AG, Jansen-West K, Muschol M, Banko J, Golde T, Weeber EJ, et al. P3-425: Chaperone-mediated modulation of tau aggregation correlates with modifications in tau pathology and synaptic plasticity Alzheimer's & Dementia. 6: S577-S577. DOI: 10.1016/J.Jalz.2010.05.1968 |
0.778 |
|
| 2009 |
Jinwal UK, Miyata Y, Koren J, Jones JR, Trotter JH, Chang L, O'Leary J, Morgan D, Lee DC, Shults CL, Rousaki A, Weeber EJ, Zuiderweg ER, Gestwicki JE, Dickey CA. Chemical manipulation of hsp70 ATPase activity regulates tau stability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12079-88. PMID 19793966 DOI: 10.1523/Jneurosci.3345-09.2009 |
0.717 |
|
| 2009 |
Koren J, Jinwal UK, Lee DC, Jones JR, Shults CL, Johnson AG, Anderson LJ, Dickey CA. Chaperone signalling complexes in Alzheimer's disease. Journal of Cellular and Molecular Medicine. 13: 619-30. PMID 19449461 DOI: 10.1111/J.1582-4934.2008.00557.X |
0.707 |
|
| 2009 |
Dickey C, Kraft C, Jinwal U, Koren J, Johnson A, Anderson L, Lebson L, Lee D, Dickson D, de Silva R, Binder LI, Morgan D, Lewis J. Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy. The American Journal of Pathology. 174: 228-38. PMID 19074615 DOI: 10.2353/Ajpath.2009.080764 |
0.712 |
|
| 2009 |
Dickey CA, Jinwal UK, Koren J, O'Leary J, Anderson L, Jones J, Shults C, Jin Y, Johnson A, Abisambra J, Morgan D, Lee DC, Chang L, Miyata Y, Thompson A, et al. P2-198: Chemical manipulation of Hsp70 activity regulates tau processing Alzheimer's & Dementia. 5: P319-P319. DOI: 10.1016/J.Jalz.2009.04.510 |
0.802 |
|
| 2008 |
Dickey CA, Koren J, Zhang YJ, Xu YF, Jinwal UK, Birnbaum MJ, Monks B, Sun M, Cheng JQ, Patterson C, Bailey RM, Dunmore J, Soresh S, Leon C, Morgan D, et al. Akt and CHIP coregulate tau degradation through coordinated interactions. Proceedings of the National Academy of Sciences of the United States of America. 105: 3622-7. PMID 18292230 DOI: 10.1073/Pnas.0709180105 |
0.789 |
|
| 2008 |
Dickey CA, Koren J, Zhang Y, Xu Y, Jinwal U, Bailey R, Dunmore J, Birnbaum M, Morgan D, Petrucelli L. O1-06-03: Akt functions to regulate the chaperone complex and attenuate Tau degradation Alzheimer's & Dementia. 4: T120-T120. DOI: 10.1016/J.Jalz.2008.05.258 |
0.716 |
|
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