Gang Shen, Ph.D.
Affiliations: | 2007 | Medicinal Chemistry | University of Kansas, Lawrence, KS, United States |
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"Gang Shen"Mean distance: 9.16 | S | N | B | C | P |
Parents
Sign in to add mentorBrian Blagg | grad student | 2007 | University of Kansas | |
(Targeting both ends of Hsp90: Chimeric N-terminal inhibitors and novobiocin-derivatized C-terminal inhibitors.) |
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Publications
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Shen G, Wang M, Welch TR, et al. (2006) Design, synthesis, and structure--activity relationships for chimeric inhibitors of Hsp90. The Journal of Organic Chemistry. 71: 7618-31 |
Wang M, Shen G, Blagg BS. (2006) Radanamycin, a macrocyclic chimera of radicicol and geldanamycin. Bioorganic & Medicinal Chemistry Letters. 16: 2459-62 |
Yu XM, Shen G, Neckers L, et al. (2005) Hsp90 inhibitors identified from a library of novobiocin analogues. Journal of the American Chemical Society. 127: 12778-9 |
Shen G, Blagg BS. (2005) Radester, a novel inhibitor of the Hsp90 protein folding machinery. Organic Letters. 7: 2157-60 |
Shen G, Yu XM, Blagg BS. (2004) Syntheses of photolabile novobiocin analogues. Bioorganic & Medicinal Chemistry Letters. 14: 5903-6 |
Yu XM, Shen G, Blagg BS. (2004) Synthesis of (-)-noviose from 2,3-O-isopropylidene-D-erythronolactol. The Journal of Organic Chemistry. 69: 7375-8 |