Hasan Yardimci, Ph.D.

Affiliations: 
2006 Johns Hopkins University, Baltimore, MD 
Area:
Condensed Matter Physics, Physical Chemistry
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"Hasan Yardimci"

Parents

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Robert L. Leheny grad student 2006 Johns Hopkins
 (Slowing dynamics in supercooled liquids and other soft materials.)
Johannes C. Walter post-doc 2009-2013 Harvard Medical School (Chemistry Tree)
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Publications

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Kose HB, Xie S, Cameron G, et al. (2020) Duplex DNA engagement and RPA oppositely regulate the DNA-unwinding rate of CMG helicase. Nature Communications. 11: 3713
Eickhoff P, Kose HB, Martino F, et al. (2019) Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Reports. 28: 2673-2688.e8
Burnham DR, Kose HB, Hoyle RB, et al. (2019) The mechanism of DNA unwinding by the eukaryotic replicative helicase. Nature Communications. 10: 2159
Kose HB, Larsen NB, Duxin JP, et al. (2019) Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model. Cell Reports. 26: 2113-2125.e6
Yardimci H, Zhang Y. (2015) Charting oxidized methylcytosines at base resolution. Nature Structural & Molecular Biology. 22: 656-61
Duxin JP, Dewar JM, Yardimci H, et al. (2014) Repair of a DNA-protein crosslink by replication-coupled proteolysis. Cell. 159: 346-57
Yardimci H, Walter JC. (2014) Prereplication-complex formation: a molecular double take? Nature Structural & Molecular Biology. 21: 20-5
Yardimci H, Wang X, Loveland AB, et al. (2012) Bypass of a protein barrier by a replicative DNA helicase. Nature. 492: 205-9
Yardimci H, Loveland AB, van Oijen AM, et al. (2012) Single-molecule analysis of DNA replication in Xenopus egg extracts. Methods (San Diego, Calif.). 57: 179-86
Fu YV, Yardimci H, Long DT, et al. (2011) Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase. Cell. 146: 931-41
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