Santoshanand V. Thakkar, Ph.D.
Affiliations: | 2012 | Pharmaceutical Chemistry | University of Kansas, Lawrence, KS, United States |
Area:
Pharmacy, General BiophysicsGoogle:
"Santoshanand Thakkar"Parents
Sign in to add mentor| Charles Russell Middaugh | grad student | 2012 | University of Kansas (Chemistry Tree) | |
| (Studies on the conformational stability, dynamics and viscosity of immunoglobulins.) | ||||
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Publications
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| Thakkar SV, Sahni N, Joshi SB, et al. (2013) Understanding the relevance of local conformational stability and dynamics to the aggregation propensity of an IgG1 and IgG2 monoclonal antibodies. Protein Science : a Publication of the Protein Society. 22: 1295-305 |
| Manikwar P, Majumdar R, Hickey JM, et al. (2013) Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium-exchange mass spectrometry. Journal of Pharmaceutical Sciences. 102: 2136-51 |
| Fakhari A, Phan Q, Thakkar SV, et al. (2013) Hyaluronic acid nanoparticles titrate the viscoelastic properties of viscosupplements. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 5123-31 |
| Thakkar SV, Kim JH, Samra HS, et al. (2012) Local dynamics and their alteration by excipients modulate the global conformational stability of an lgG1 monoclonal antibody. Journal of Pharmaceutical Sciences. 101: 4444-57 |
| Hu L, Joshi SB, Andra KK, et al. (2012) Comparison of the structural stability and dynamic properties of recombinant anthrax protective antigen and its 2-fluorohistidine-labeled analogue. Journal of Pharmaceutical Sciences. 101: 4118-28 |
| Thakkar SV, Allegre KM, Joshi SB, et al. (2012) An application of ultraviolet spectroscopy to study interactions in proteins solutions at high concentrations. Journal of Pharmaceutical Sciences. 101: 3051-61 |
| Thakkar SV, Joshi SB, Jones ME, et al. (2012) Excipients differentially influence the conformational stability and pretransition dynamics of two IgG1 monoclonal antibodies. Journal of Pharmaceutical Sciences. 101: 3062-77 |