Nicholas Furnham
Affiliations: | European Bioinformatics Institute, Hinxton, England, United Kingdom |
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Sign in to add mentor| Janet M. Thornton | research scientist | European Bioinformatics Institute |
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| de Souza Neto LR, Moreira-Filho JT, Neves BJ, et al. (2020) Strategies to Support Fragment-to-Lead Optimization in Drug Discovery. Frontiers in Chemistry. 8: 93 |
| Tyzack JD, Furnham N, Sillitoe I, et al. (2019) Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function. Methods in Molecular Biology (Clifton, N.J.). 1851: 263-275 |
| Valasatava Y, Rosato A, Furnham N, et al. (2017) To what extent do structural changes in catalytic metal sites affect enzyme function? Journal of Inorganic Biochemistry. 179: 40-53 |
| Ribeiro AJM, Holliday GL, Furnham N, et al. (2017) Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites. Nucleic Acids Research |
| Tyzack JD, Furnham N, Sillitoe I, et al. (2017) Understanding enzyme function evolution from a computational perspective. Current Opinion in Structural Biology. 47: 131-139 |
| Furnham N. (2017) Complementary Sources of Protein Functional Information: The Far Side of GO. Methods in Molecular Biology (Clifton, N.J.). 1446: 263-274 |
| Mascotti ML, Ayub MJ, Furnham N, et al. (2016) Chopping and changing: The evolution of the flavin-dependent monooxygenases. Journal of Molecular Biology |
| Phelan J, Coll F, McNerney R, et al. (2016) Mycobacterium tuberculosis whole genome sequencing and protein structure modelling provides insights into anti-tuberculosis drug resistance. Bmc Medicine. 14: 31 |
| Sillitoe I, Furnham N. (2015) FunTree: advances in a resource for exploring and contextualising protein function evolution. Nucleic Acids Research |
| Furnham N, Dawson NL, Rahman SA, et al. (2015) Large-Scale Analysis Exploring Evolution of Catalytic Machineries and Mechanisms in Enzyme Superfamilies. Journal of Molecular Biology |