Prabodhika Mallikaratchy, Ph.D.

Affiliations: 
2007 University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Analytical Chemistry, Biochemistry
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"Prabodhika Mallikaratchy"
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Parents

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Weihong Tan grad student 2007 UF Gainesville
 (In vitro selection and development of aptamers for biomarker discovery and targeted therapy.)
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Publications

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Williams N, Patel R, Mallikaratchy P. (2022) Discovery of Aptamers Against Cell Surface Markers Using Ligand-Guided Selection. Methods in Molecular Biology (Clifton, N.J.). 2570: 13-38
Williams NB, Batool S, Zumrut HE, et al. (2022) An Selection Platform to Identify Multiple Aptamers against Multiple Cell-Surface Markers Using Ligand-Guided Selection. Biochemistry
Boykoff N, Freage L, Lenn J, et al. (2021) Bispecific Aptamer Sensor toward T-Cell Leukemia Detection in the Tumor Microenvironment. Acs Omega. 6: 32563-32570
Zumrut HE, Mallikaratchy PR. (2020) Ligand Guided Selection (LIGS) of Artificial Nucleic Acid Ligands against Cell Surface Targets. Acs Applied Bio Materials. 3: 2545-2552
Freage L, Jamal D, Williams NB, et al. (2020) A Homodimeric Aptamer Variant Generated from Ligand-Guided Selection Activates the T Cell Receptor Cluster of Differentiation 3 Complex. Molecular Therapy. Nucleic Acids. 22: 167-178
Zumrut H, Yang Z, Williams N, et al. (2019) Ligand Guided Selection (LIGS) with Artificially Expanded Genetic Information Systems against TCR-CD3ε. Biochemistry
Zumrut HE, Batool S, Argyropoulos KV, et al. (2019) Integrating Ligand-Receptor Interactions and In Vitro Evolution for Streamlined Discovery of Artificial Nucleic Acid Ligands. Molecular Therapy. Nucleic Acids. 17: 150-163
Moccia F, Platella C, Musumeci D, et al. (2019) The role of G-quadruplex structures of LIGS-generated aptamers R1.2 and R1.3 in IgM specific recognition. International Journal of Biological Macromolecules
Batool S, Argyropoulos KV, Azad R, et al. (2018) Dimerization of an aptamer generated from Ligand-guided selection (LIGS) yields a high affinity scaffold against B-cells. Biochimica Et Biophysica Acta. General Subjects
Batool S, Bhandari S, George S, et al. (2017) Engineered Aptamers to Probe Molecular Interactions on the Cell Surface. Biomedicines. 5
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