| Year |
Citation |
Score |
| 2023 |
Tripathi P, Mousa JJ, Guntaka NS, Bruner SD. Structural basis of the amidase ClbL central to the biosynthesis of the genotoxin colibactin. Acta Crystallographica. Section D, Structural Biology. 79: 830-836. PMID 37561403 DOI: 10.1107/S2059798323005703 |
0.751 |
|
| 2021 |
Li G, Patel K, Zhang Y, Pugmire J, Ding Y, Bruner SD. Structural and biochemical studies of an iterative ribosomal peptide macrocyclase. Proteins. PMID 34664307 DOI: 10.1002/prot.26264 |
0.326 |
|
| 2021 |
Li Q, Zallot R, MacTavish BS, Montoya A, Payan DJ, Hu Y, Gerlt JA, Angerhofer A, de Crécy-Lagard V, Bruner SD. Epoxyqueuosine Reductase QueH in the Biosynthetic Pathway to tRNA Queuosine Is a Unique Metalloenzyme. Biochemistry. PMID 34652139 DOI: 10.1021/acs.biochem.1c00164 |
0.321 |
|
| 2021 |
Patel KP, Silsby LM, Li G, Bruner SD. Structure-Based Engineering of Peptide Macrocyclases for the Chemoenzymatic Synthesis of Microviridins. The Journal of Organic Chemistry. PMID 34263606 DOI: 10.1021/acs.joc.1c00785 |
0.306 |
|
| 2021 |
Tripathi P, Bruner SD. Structural Basis for the Interactions of the Colibactin Resistance Gene Product ClbS with DNA. Biochemistry. PMID 33945270 DOI: 10.1021/acs.biochem.1c00201 |
0.742 |
|
| 2020 |
Zhang P, MacTavish BS, Yang G, Chen M, Roh J, Newsome KR, Bruner SD, Ding Y. Cyanobacterial Dihydroxyacid Dehydratases Are a Promising Growth Inhibition Target. Acs Chemical Biology. PMID 32786290 DOI: 10.1021/Acschembio.0C00507 |
0.319 |
|
| 2020 |
Patterson JA, He H, Folz JS, Li Q, Wilson MA, Fiehn O, Bruner SD, Bar-Even A, Hanson AD. Thioproline formation as a driver of formaldehyde toxicity in Escherichia coli. The Biochemical Journal. PMID 32301498 DOI: 10.1042/Bcj20200198 |
0.396 |
|
| 2019 |
Niehaus TD, Patterson JA, Alexander DC, Folz JS, Pyc M, MacTavish BS, Bruner SD, Mullen RT, Fiehn O, Hanson AD. The metabolite repair enzyme Nit1 is a dual-targeted amidase that disposes of damaged glutathione in . The Biochemical Journal. PMID 30692244 DOI: 10.1042/Bcj20180931 |
0.359 |
|
| 2018 |
Zhang Y, Chen M, Bruner SD, Ding Y. Heterologous Production of Microbial Ribosomally Synthesized and Post-translationally Modified Peptides. Frontiers in Microbiology. 9: 1801. PMID 30135682 DOI: 10.3389/Fmicb.2018.01801 |
0.352 |
|
| 2018 |
Beaudoin GAW, Li Q, Folz J, Fiehn O, Goodsell JL, Angerhofer A, Bruner SD, Hanson AD. Salvage of the 5-deoxyribose byproduct of radical SAM enzymes. Nature Communications. 9: 3105. PMID 30082730 DOI: 10.1038/S41467-018-05589-4 |
0.401 |
|
| 2018 |
Zhang Y, Li K, Yang G, McBride JL, Bruner SD, Ding Y. A distributive peptide cyclase processes multiple microviridin core peptides within a single polypeptide substrate. Nature Communications. 9: 1780. PMID 29725007 DOI: 10.1038/S41467-018-04154-3 |
0.677 |
|
| 2018 |
Sun X, Winglee K, Gharaibeh RZ, Gauthier J, He Z, Tripathi P, Avram D, Bruner S, Fodor A, Jobin C. Microbiota-derived Metabolic Factors Reduce Campylobacteriosis in Mice. Gastroenterology. PMID 29408609 DOI: 10.1053/J.Gastro.2018.01.042 |
0.671 |
|
| 2017 |
Beaudoin GA, Li Q, Bruner SD, Hanson AD. An Unusual Diphosphatase from the PhnP Family Cleaves Reactive FAD Photoproducts. The Biochemical Journal. PMID 29229761 DOI: 10.1042/Bcj20170817 |
0.393 |
|
| 2017 |
Tripathi P, Shine EE, Healy AR, Kim CS, Herzon SB, Bruner SD, Crawford JM. ClbS is a cyclopropane hydrolase that confers colibactin resistance. Journal of the American Chemical Society. PMID 29112397 DOI: 10.1021/Jacs.7B09971 |
0.742 |
|
| 2017 |
Sun J, Jeffryes JG, Henry CS, Bruner SD, Hanson AD. Metabolite damage and repair in metabolic engineering design. Metabolic Engineering. PMID 29030275 DOI: 10.1016/J.Ymben.2017.10.006 |
0.35 |
|
| 2017 |
Guntaka NS, Healy AR, Crawford JM, Herzon SB, Bruner SD. Structure and Functional Analysis of ClbQ, an Unusual Intermediate-Releasing Thioesterase from the Colibactin Biosynthetic Pathway. Acs Chemical Biology. PMID 28846367 DOI: 10.1021/Acschembio.7B00479 |
0.434 |
|
| 2017 |
Zhang P, Li K, Yang G, Xia C, Polston JE, Li G, Li S, Lin Z, Yang LJ, Bruner SD, Ding Y. Cytotoxic protein from the mushroom Coprinus comatus possesses a unique mode for glycan binding and specificity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28784797 DOI: 10.1073/Pnas.1706894114 |
0.716 |
|
| 2017 |
Thamm AM, Li G, Taja-Moreno M, Gerdes SY, de Crécy-Lagard V, Bruner SD, Hanson AD. A strictly monofunctional bacterial hydroxymethylpyrimidine phosphate kinase precludes damaging errors in thiamin biosynthesis. The Biochemical Journal. PMID 28729425 DOI: 10.1042/Bcj20170437 |
0.367 |
|
| 2017 |
Li K, Fielding EN, Condurso HL, Bruner SD. Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase. Acta Crystallographica. Section D, Structural Biology. 73: 573-580. PMID 28695857 DOI: 10.1107/S2059798317007045 |
0.703 |
|
| 2017 |
Zuo R, Zhang Y, Jiang C, Hackett JC, Loria R, Bruner SD, Ding Y. Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration. Scientific Reports. 7: 842. PMID 28405004 DOI: 10.1038/S41598-017-00897-Z |
0.331 |
|
| 2017 |
Zallot R, Ross R, Chen WH, Bruner SD, Limbach PA, De Crecy-Lagard V. Identification of a novel epoxyqueuosine reductase family by comparative genomics. Acs Chemical Biology. PMID 28128549 DOI: 10.1021/Acschembio.6B01100 |
0.322 |
|
| 2016 |
Mousa JJ, Newsome RC, Yang Y, Jobin C, Bruner SD. ClbM is a versatile, cation-promiscuous MATE multi-drug transporter found in the colibactin biosynthetic gene cluster. Biochemical and Biophysical Research Communications. PMID 27939886 DOI: 10.1016/J.Bbrc.2016.12.018 |
0.313 |
|
| 2016 |
Li K, Condurso HL, Li G, Ding Y, Bruner SD. Structural basis for precursor protein-directed ribosomal peptide macrocyclization. Nature Chemical Biology. PMID 27669417 DOI: 10.1038/Nchembio.2200 |
0.708 |
|
| 2016 |
Mousa JJ, Yang Y, Tomkovich S, Shima A, Newsome RC, Tripathi P, Oswald E, Bruner SD, Jobin C. MATE transport of the E. coli-derived genotoxin colibactin. Nature Microbiology. 1: 15009. PMID 27571755 DOI: 10.1038/Nmicrobiol.2015.9 |
0.734 |
|
| 2016 |
Zhang X, Li K, Jones RA, Bruner SD, Butcher RA. Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. PMID 27551084 DOI: 10.1073/Pnas.1608262113 |
0.719 |
|
| 2016 |
Mousa JJ, Bruner SD. Structural and mechanistic diversity of multidrug transporters. Natural Product Reports. PMID 27472662 DOI: 10.1039/C6Np00006A |
0.307 |
|
| 2016 |
Chen WH, Li K, Guntaka NS, Bruner SD. Interdomain and intermodule organization in epimerization domain containing nonribosomal peptide synthetases. Acs Chemical Biology. PMID 27294598 DOI: 10.1021/Acschembio.6B00332 |
0.698 |
|
| 2016 |
Li K, Chen WH, Bruner SD. Microbial siderophore-based iron assimilation and therapeutic applications. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. PMID 27146331 DOI: 10.1007/S10534-016-9935-3 |
0.701 |
|
| 2016 |
Zuo R, Zhang Y, Huguet-Tapia JC, Mehta M, Dedic E, Bruner SD, Loria R, Ding Y. An artificial self-sufficient cytochrome P450 directly nitrates fluorinated tryptophan analogs with a different regio-selectivity. Biotechnology Journal. PMID 26743860 DOI: 10.1002/Biot.201500416 |
0.345 |
|
| 2015 |
Li K, Li G, Bradbury LM, Hanson AD, Bruner SD. Crystal structure of the homocysteine methyltransferase MmuM from Escherichia coli. The Biochemical Journal. PMID 26564203 DOI: 10.1042/Bj20150980 |
0.744 |
|
| 2015 |
Li K, Bruner SD. Structure and functional analysis of the siderophore periplasmic binding protein from the fuscachelin gene cluster of Thermobifida fusca. Proteins. PMID 26537767 DOI: 10.1002/Prot.24959 |
0.724 |
|
| 2015 |
Di Russo NV, Condurso HL, Li K, Bruner SD, Roitberg AE. Oxygen diffusion pathways in a cofactor-independent dioxygenase. Chemical Science (Royal Society of Chemistry : 2010). 6: 6341-6348. PMID 26508997 DOI: 10.1039/C5Sc01638J |
0.68 |
|
| 2015 |
Li K, Chen WH, Bruner SD. Structure and Mechanism of the Siderophore-Interacting Protein from the Fuscachelin Gene Cluster of Thermobifida fusca. Biochemistry. 54: 3989-4000. PMID 26043104 DOI: 10.1021/Acs.Biochem.5B00354 |
0.712 |
|
| 2012 |
Condurso HL, Bruner SD. Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery. Natural Product Reports. 29: 1099-110. PMID 22729219 DOI: 10.1039/C2Np20023F |
0.366 |
|
| 2012 |
Dimise EJ, Condurso HL, Stoker GE, Bruner SD. Synthesis and structure confirmation of fuscachelins A and B, structurally unique natural product siderophores from Thermobifida fusca. Organic & Biomolecular Chemistry. 10: 5353-6. PMID 22688132 DOI: 10.1039/C2Ob26010G |
0.358 |
|
| 2012 |
Condurso HL, Bruner SD. Structure guided approaches toward exploiting and manipulating nonribosomal peptide and polyketide biosynthetic pathways. Current Opinion in Chemical Biology. 16: 162-9. PMID 22369855 DOI: 10.1016/J.Cbpa.2012.02.002 |
0.415 |
|
| 2011 |
Liu Y, Zheng T, Bruner SD. Structural basis for phosphopantetheinyl carrier domain interactions in the terminal module of nonribosomal peptide synthetases. Chemistry & Biology. 18: 1482-8. PMID 22118682 DOI: 10.1016/J.Chembiol.2011.09.018 |
0.412 |
|
| 2011 |
Bruner SD. Enzyme catalysis: C-H activation is a Reiske business. Nature Chemistry. 3: 342-3. PMID 21505488 DOI: 10.1038/Nchem.1038 |
0.358 |
|
| 2010 |
Cooke HA, Bruner SD. Probing the active site of MIO-dependent aminomutases, key catalysts in the biosynthesis of beta-amino acids incorporated in secondary metabolites. Biopolymers. 93: 802-10. PMID 20577998 DOI: 10.1002/Bip.21500 |
0.427 |
|
| 2009 |
Cooke HA, Guenther EL, Luo Y, Shen B, Bruner SD. Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Biochemistry. 48: 9590-8. PMID 19702337 DOI: 10.1021/Bi901257Q |
0.482 |
|
| 2009 |
Cooke HA, Christianson CV, Bruner SD. Structure and chemistry of 4-methylideneimidazole-5-one containing enzymes. Current Opinion in Chemical Biology. 13: 460-8. PMID 19620019 DOI: 10.1016/J.Cbpa.2009.06.013 |
0.42 |
|
| 2008 |
Dimise EJ, Widboom PF, Bruner SD. Structure elucidation and biosynthesis of fuscachelins, peptide siderophores from the moderate thermophile Thermobifida fusca. Proceedings of the National Academy of Sciences of the United States of America. 105: 15311-6. PMID 18832174 DOI: 10.1073/Pnas.0805451105 |
0.387 |
|
| 2008 |
Luo Y, Lin S, Zhang J, Cooke HA, Bruner SD, Shen B. Regiospecific O-methylation of naphthoic acids catalyzed by NcsB1, an O-methyltransferase involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. The Journal of Biological Chemistry. 283: 14694-702. PMID 18387946 DOI: 10.1074/Jbc.M802206200 |
0.32 |
|
| 2008 |
Montavon TJ, Christianson CV, Festin GM, Shen B, Bruner SD. Design and characterization of mechanism-based inhibitors for the tyrosine aminomutase SgTAM. Bioorganic & Medicinal Chemistry Letters. 18: 3099-102. PMID 18078753 DOI: 10.1016/J.Bmcl.2007.11.046 |
0.373 |
|
| 2007 |
Christianson CV, Montavon TJ, Festin GM, Cooke HA, Shen B, Bruner SD. The mechanism of MIO-based aminomutases in beta-amino acid biosynthesis. Journal of the American Chemical Society. 129: 15744-5. PMID 18052279 DOI: 10.1021/Ja0762689 |
0.357 |
|
| 2007 |
Fielding EN, Widboom PF, Bruner SD. Substrate recognition and catalysis by the cofactor-independent dioxygenase DpgC. Biochemistry. 46: 13994-4000. PMID 18004875 DOI: 10.1021/Bi701148B |
0.453 |
|
| 2007 |
Cooke HA, Zhang J, Griffin MA, Nonaka K, Van Lanen SG, Shen B, Bruner SD. Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Journal of the American Chemical Society. 129: 7728-9. PMID 17539640 DOI: 10.1021/Ja071886A |
0.336 |
|
| 2007 |
Christianson CV, Montavon TJ, Van Lanen SG, Shen B, Bruner SD. The structure of L-tyrosine 2,3-aminomutase from the C-1027 enediyne antitumor antibiotic biosynthetic pathway. Biochemistry. 46: 7205-14. PMID 17516659 DOI: 10.1021/Bi7003685 |
0.416 |
|
| 2007 |
Widboom PF, Fielding EN, Liu Y, Bruner SD. Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis. Nature. 447: 342-5. PMID 17507985 DOI: 10.1038/Nature05702 |
0.394 |
|
| 2004 |
Tseng CC, Vaillancourt FH, Bruner SD, Walsh CT. DpgC is a metal- and cofactor-free 3,5-dihydroxyphenylacetyl-CoA 1,2-dioxygenase in the vancomycin biosynthetic pathway. Chemistry & Biology. 11: 1195-203. PMID 15380180 DOI: 10.1016/J.Chembiol.2004.06.012 |
0.487 |
|
| 2004 |
Yeh E, Kohli RM, Bruner SD, Walsh CT. Type II thioesterase restores activity of a NRPS module stalled with an aminoacyl-S-enzyme that cannot be elongated. Chembiochem : a European Journal of Chemical Biology. 5: 1290-3. PMID 15368584 DOI: 10.1002/Cbic.200400077 |
0.441 |
|
| 2003 |
Fromme JC, Bruner SD, Yang W, Karplus M, Verdine GL. Product-assisted catalysis in base-excision DNA repair. Nature Structural Biology. 10: 204-11. PMID 12592398 DOI: 10.1038/Nsb902 |
0.758 |
|
| 2002 |
Tseng CC, Bruner SD, Kohli RM, Marahiel MA, Walsh CT, Sieber SA. Characterization of the surfactin synthetase C-terminal thioesterase domain as a cyclic depsipeptide synthase. Biochemistry. 41: 13350-9. PMID 12416979 DOI: 10.1021/Bi026592A |
0.553 |
|
| 2002 |
Bruner SD, Weber T, Kohli RM, Schwarzer D, Marahiel MA, Walsh CT, Stubbs MT. Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE. Structure (London, England : 1993). 10: 301-10. PMID 12005429 DOI: 10.1016/S0969-2126(02)00716-5 |
0.545 |
|
| 2001 |
Norman DP, Bruner SD, Verdine GL. Coupling of substrate recognition and catalysis by a human base-excision DNA repair protein. Journal of the American Chemical Society. 123: 359-60. PMID 11456534 DOI: 10.1021/Ja003144M |
0.776 |
|
| 2000 |
Bruner SD, Norman DP, Fromme JC, Verdine GL. Structural and mechanistic studies on repair of 8-oxoguanine in mammalian cells. Cold Spring Harbor Symposia On Quantitative Biology. 65: 103-11. PMID 12760025 DOI: 10.1101/Sqb.2000.65.103 |
0.741 |
|
| 2000 |
Sekino Y, Bruner SD, Verdine GL. Selective inhibition of herpes simplex virus type-1 uracil-DNA glycosylase by designed substrate analogs. The Journal of Biological Chemistry. 275: 36506-8. PMID 11084051 DOI: 10.1074/Jbc.C000585200 |
0.588 |
|
| 2000 |
Bruner SD, Norman DP, Verdine GL. Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA. Nature. 403: 859-66. PMID 10706276 DOI: 10.1038/35002510 |
0.768 |
|
| 1998 |
Bruner SD, Nash HM, Lane WS, Verdine GL. Repair of oxidatively damaged guanine in Saccharomyces cerevisiae by an alternative pathway. Current Biology : Cb. 8: 393-403. PMID 9545197 DOI: 10.1016/S0960-9822(98)70158-7 |
0.597 |
|
| 1997 |
Radeke HS, Digits CA, Bruner SD, Snapper ML. New Tools for Studying Vesicular-Mediated Protein Trafficking: Synthesis and Evaluation of Ilimaquinone Analogs in a Non-Radioisotope-Based Antisecretory Assay. The Journal of Organic Chemistry. 62: 2823-2831. PMID 11671645 DOI: 10.1021/Jo962292L |
0.354 |
|
| 1997 |
Verdine GL, Bruner SD. How do DNA repair proteins locate damaged bases in the genome? Chemistry & Biology. 4: 329-34. PMID 9195879 DOI: 10.1016/S1074-5521(97)90123-X |
0.546 |
|
| 1996 |
Nash HM, Bruner SD, Schärer OD, Kawate T, Addona TA, Spooner E, Lane WS, Verdine GL. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Current Biology : Cb. 6: 968-80. PMID 8805338 DOI: 10.1016/S0960-9822(02)00641-3 |
0.616 |
|
| Show low-probability matches. |