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Tao Huang, Ph.D. - Publications

Affiliations: 
University of Virginia, Charlottesville, VA 
Area:
Bioorganic and Synthetic Organic Chemistry
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13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kharel Y, Huang T, Salamon A, Harris TE, Santos WL, Lynch KR. Correction: Mechanism of sphingosine 1-phosphate clearance from blood. The Biochemical Journal. 480: 2059-2060. PMID 38108461 DOI: 10.1042/BCJ20190730_COR  0.498
2023 Shrader CW, Foster D, Kharel Y, Huang T, Lynch KR, Santos WL. Imidazole-based sphingosine-1-phosphate transporter Spns2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 129516. PMID 37832799 DOI: 10.1016/j.bmcl.2023.129516  0.601
2023 Kharel Y, Huang T, Santos WL, Lynch KR. Assay of Sphingosine 1-phosphate Transporter Spinster Homolog 2 (Spns2) Inhibitors. Slas Discovery : Advancing Life Sciences R & D. PMID 37454972 DOI: 10.1016/j.slasd.2023.07.001  0.608
2023 Burgio AL, Shrader CW, Kharel Y, Huang T, Salamoun JM, Lynch KR, Santos WL. 2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2). Journal of Medicinal Chemistry. PMID 37010497 DOI: 10.1021/acs.jmedchem.3c00149  0.607
2022 Tanaka S, Zheng S, Kharel Y, Fritzemeier RG, Huang T, Foster D, Poudel N, Goggins E, Yamaoka Y, Rudnicka KP, Lipsey JE, Radel HV, Ryuh SM, Inoue T, Yao J, et al. Sphingosine 1-phosphate signaling in perivascular cells enhances inflammation and fibrosis in the kidney. Science Translational Medicine. 14: eabj2681. PMID 35976996 DOI: 10.1126/scitranslmed.abj2681  0.588
2022 Fritzemeier R, Foster D, Peralta A, Payette M, Kharel Y, Huang T, Lynch KR, Santos WL. Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors. Journal of Medicinal Chemistry. PMID 35609189 DOI: 10.1021/acs.jmedchem.1c02171  0.615
2020 Li H, Sibley CD, Kharel Y, Huang T, Brown AM, Wonilowicz LG, Bevan DR, Lynch KR, Santos WL. Lipophilic tail modifications of 2-(hydroxymethyl)pyrrolidine scaffold reveal dual sphingosine kinase 1 and 2 inhibitors. Bioorganic & Medicinal Chemistry. 30: 115941. PMID 33385956 DOI: 10.1016/j.bmc.2020.115941  0.588
2020 Kharel Y, Huang T, Salamon A, Harris T, Santos WL, Lynch KR. Mechanism of sphingosine 1-phosphate clearance from blood. The Biochemical Journal. PMID 32065229 DOI: 10.1042/Bcj20190730  0.63
2018 Kharel Y, Agah S, Huang T, Mendelson AJ, Eletu OT, Barkey-Bircann P, Gesualdi J, Smith JS, Santos WL, Lynch KR. Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors. Plos One. 13: e0192179. PMID 29672528 DOI: 10.1371/Journal.Pone.0192179  0.567
2017 Liu C, Cui P, Huang T. Identification of cell cycle-regulated genes by convolutional neural network. Combinatorial Chemistry & High Throughput Screening. PMID 28413974 DOI: 10.2174/1386207320666170417144937  0.319
2011 Kennedy PC, Zhu R, Huang T, Tomsig JL, Mathews TP, David M, Peyruchaud O, Macdonald TL, Lynch KR. Characterization of a sphingosine 1-phosphate receptor antagonist prodrug. The Journal of Pharmacology and Experimental Therapeutics. 338: 879-89. PMID 21632869 DOI: 10.1124/Jpet.111.181552  0.702
2010 Yang M, Chordia MD, Li F, Huang T, Linden J, MacDonald TL. Neutrophil- and myeloperoxidase-mediated metabolism of reduced nimesulide: Evidence for bioactivation Chemical Research in Toxicology. 23: 1691-1700. PMID 20939553 DOI: 10.1021/Tx1001496  0.671
2009 Li F, Chordia MD, Huang T, Macdonald TL. In vitro nimesulide studies toward understanding idiosyncratic hepatotoxicity: Diiminoquinone formation and conjugation Chemical Research in Toxicology. 22: 72-80. PMID 19053182 DOI: 10.1021/Tx800152R  0.654
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