| Year |
Citation |
Score |
| 2024 |
Safren N, Dao TP, Mohan HM, Huang C, Trotter B, Castañeda CA, Paulson H, Barmada S, Sharkey LM. Pathogenic mutations in UBQLN2 exhibit diverse aggregation propensity and neurotoxicity. Scientific Reports. 14: 6049. PMID 38472280 DOI: 10.1038/s41598-024-55582-9 |
0.345 |
|
| 2023 |
Maltby CJ, Krans A, Grudzien SJ, Palacios Y, Muiños J, Suárez A, Asher M, Khurana V, Barmada SJ, Dijkstra AA, Todd PK. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. Biorxiv : the Preprint Server For Biology. PMID 38168171 DOI: 10.1101/2023.12.13.571345 |
0.356 |
|
| 2023 |
Malik AM, Wu JJ, Gillies CA, Doctrove QA, Li X, Huang H, Tank EHM, Shakkottai VG, Barmada S. Neuronal activity regulates Matrin 3 abundance and function in a calcium-dependent manner through calpain-mediated cleavage and calmodulin binding. Proceedings of the National Academy of Sciences of the United States of America. 120: e2206217120. PMID 37011198 DOI: 10.1073/pnas.2206217120 |
0.324 |
|
| 2023 |
Ervilha Pereira P, Schuermans N, Meylemans A, LeBlanc P, Versluys L, Copley KE, Rubien JD, Altheimer C, Peetermans M, Debackere E, Vanakker O, Janssens S, Baets J, Verhoeven K, Lammens M, ... ... Barmada SJ, et al. C-terminal frameshift variant of TDP-43 with pronounced aggregation-propensity causes rimmed vacuole myopathy but not ALS/FTD. Acta Neuropathologica. PMID 37000196 DOI: 10.1007/s00401-023-02565-1 |
0.37 |
|
| 2023 |
Pinarbasi ES, Barmada SJ. Glia in FTLD-GRN: from supporting cast to leading role. The Journal of Clinical Investigation. 133. PMID 36919702 DOI: 10.1172/JCI168215 |
0.305 |
|
| 2022 |
Safren N, Sharkey LM, Barmada SJ. Neuronal Puncta/Aggregate Formation by WT and Mutant UBQLN2. Methods in Molecular Biology (Clifton, N.J.). 2551: 561-573. PMID 36310225 DOI: 10.1007/978-1-0716-2597-2_34 |
0.372 |
|
| 2022 |
François-Moutal L, Scott DD, Ambrose AJ, Zerio CJ, Rodriguez-Sanchez M, Dissanayake K, May DG, Carlson JM, Barbieri E, Moutal A, Roux KJ, Shorter J, Khanna R, Barmada SJ, McGurk L, et al. Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology. Scientific Reports. 12: 8140. PMID 35581326 DOI: 10.1038/s41598-022-12191-8 |
0.339 |
|
| 2022 |
Chua JP, Bedi K, Paulsen MT, Ljungman M, Tank EMH, Kim ES, McBride JP, Colón-Mercado JM, Ward ME, Weisman LS, Barmada SJ. Myotubularin-related phosphatase 5 is a critical determinant of autophagy in neurons. Current Biology : Cb. PMID 35580604 DOI: 10.1016/j.cub.2022.04.053 |
0.332 |
|
| 2022 |
Gerson JE, Sandoval-Pistorius S, Welday JP, Rodriguez A, Gregory JD, Liggans N, Schache K, Li X, Trzeciakiewicz H, Barmada S, Sharkey LM, Paulson HL. Disrupting the balance of protein quality control protein UBQLN2 accelerates tau proteinopathy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35082119 DOI: 10.1523/JNEUROSCI.1116-21.2021 |
0.36 |
|
| 2021 |
Safren N, Tank EM, Malik AM, Chua JP, Santoro N, Barmada SJ. Development of a specific live-cell assay for native autophagic flux. The Journal of Biological Chemistry. 101003. PMID 34303705 DOI: 10.1016/j.jbc.2021.101003 |
0.345 |
|
| 2021 |
Maimon R, Ankol L, Gradus Pery T, Altman T, Ionescu A, Weissova R, Ostrovsky M, Tank E, Alexandra G, Shelestovich N, Opatowsky Y, Dori A, Barmada S, Balastik M, Perlson E. A CRMP4-dependent retrograde axon-to-soma death signal in amyotrophic lateral sclerosis. The Embo Journal. e107586. PMID 34190355 DOI: 10.15252/embj.2020107586 |
0.314 |
|
| 2021 |
Sidibé H, Khalfallah Y, Xiao S, Gómez NB, Fakim H, Tank EMH, Tomasso GD, Bareke E, Aulas A, McKeever PM, Melamed Z, Destroimaisons L, Deshaies JE, Zinman L, Parker JA, ... ... Barmada SJ, et al. TDP-43 stabilizes G3BP1 mRNA: relevance to amyotrophic lateral sclerosis/frontotemporal dementia. Brain : a Journal of Neurology. PMID 34115105 DOI: 10.1093/brain/awab217 |
0.304 |
|
| 2021 |
Chua JP, De Calbiac H, Kabashi E, Barmada SJ. Autophagy and ALS: mechanistic insights and therapeutic implications. Autophagy. 1-29. PMID 34057020 DOI: 10.1080/15548627.2021.1926656 |
0.385 |
|
| 2021 |
Malik AM, Barmada SJ. Matrin 3 in neuromuscular disease: physiology and pathophysiology. Jci Insight. 6. PMID 33427209 DOI: 10.1172/jci.insight.143948 |
0.335 |
|
| 2020 |
He F, Flores BN, Krans A, Frazer M, Natla S, Niraula S, Adefioye O, Barmada SJ, Todd PK. The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD. Acta Neuropathologica Communications. 8: 122. PMID 32753055 DOI: 10.1186/S40478-020-01002-8 |
0.305 |
|
| 2020 |
Gerson JE, Safren N, Fischer S, Patel R, Crowley EV, Welday JP, Windle AK, Barmada S, Paulson HL, Sharkey LM. Ubiquilin-2 differentially regulates polyglutamine disease proteins. Human Molecular Genetics. PMID 32681165 DOI: 10.1093/hmg/ddaa152 |
0.45 |
|
| 2019 |
Weskamp K, Tank EM, Miguez R, McBride JP, Gómez NB, White M, Lin Z, Moreno Gonzalez C, Serio A, Sreedharan J, Barmada SJ. Shortened TDP43 isoforms upregulated by neuronal hyperactivity drive TDP43 pathology in ALS. The Journal of Clinical Investigation. PMID 31714900 DOI: 10.1172/Jci130988 |
0.332 |
|
| 2018 |
Sharkey LM, Safren N, Pithadia AS, Gerson JE, Dulchavsky M, Fischer S, Patel R, Lantis G, Ashraf N, Kim JH, Meliki A, Minakawa EN, Barmada SJ, Ivanova MI, Paulson HL. Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 30333186 DOI: 10.1073/pnas.1810522115 |
0.352 |
|
| 2018 |
Malik AM, Miguez RA, Li X, Ho YS, Feldman EL, Barmada SJ. Matrin 3-dependent neurotoxicity is modified by nucleic acid binding and nucleocytoplasmic localization. Elife. 7. PMID 30015619 DOI: 10.7554/Elife.35977 |
0.362 |
|
| 2018 |
Park SK, Arslan F, Kanneganti V, Barmada SJ, Purushothaman P, Verma SC, Liebman SW. Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins. Prion. 0. PMID 29308690 DOI: 10.1080/19336896.2017.1423185 |
0.396 |
|
| 2017 |
Al-Ramahi I, Giridharan SSP, Chen YC, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, et al. Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein. Elife. 6. PMID 29256861 DOI: 10.7554/Elife.29123 |
0.351 |
|
| 2017 |
Wang B, Zeng L, Merillat SA, Ochaba J, Thompson LM, Barmada SJ, Scaglione KM, Paulson HL. The ubiquitin conjugating enzyme Ube2W regulates solubility of the Huntington's disease protein, huntingtin. Neurobiology of Disease. PMID 28986324 DOI: 10.1016/j.nbd.2017.10.002 |
0.363 |
|
| 2017 |
Park SK, Hong JY, Arslan F, Kanneganti V, Patel B, Tietsort A, Tank EMH, Li X, Barmada SJ, Liebman SW. Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis. Plos Genetics. 13: e1006805. PMID 28531192 DOI: 10.1371/journal.pgen.1006805 |
0.374 |
|
| 2017 |
Gupta R, Lan M, Mojsilovic-Petrovic J, Choi WH, Safren N, Barmada S, Lee MJ, Kalb R. The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the Proteasome. Eneuro. 4. PMID 28197542 DOI: 10.1523/ENEURO.0249-16.2017 |
0.329 |
|
| 2015 |
Barmada SJ, Ju S, Arjun A, Batarse A, Archbold HC, Peisach D, Li X, Zhang Y, Tank EM, Qiu H, Huang EJ, Ringe D, Petsko GA, Finkbeiner S. Amelioration of toxicity in neuronal models of amyotrophic lateral sclerosis by hUPF1. Proceedings of the National Academy of Sciences of the United States of America. 112: 7821-6. PMID 26056265 DOI: 10.1073/Pnas.1509744112 |
0.439 |
|
| 2015 |
Barmada SJ. Linking RNA Dysfunction and Neurodegeneration in Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 340-51. PMID 25689976 DOI: 10.1007/S13311-015-0340-3 |
0.404 |
|
| 2014 |
Barmada SJ, Serio A, Arjun A, Bilican B, Daub A, Ando DM, Tsvetkov A, Pleiss M, Li X, Peisach D, Shaw C, Chandran S, Finkbeiner S. Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models. Nature Chemical Biology. 10: 677-85. PMID 24974230 DOI: 10.1038/Nchembio.1563 |
0.485 |
|
| 2014 |
Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, et al. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. The Journal of Clinical Investigation. 124: 981-99. PMID 24509083 DOI: 10.1172/Jci72723 |
0.472 |
|
| 2013 |
Tsvetkov AS, Arrasate M, Barmada S, Ando DM, Sharma P, Shaby BA, Finkbeiner S. Proteostasis of polyglutamine varies among neurons and predicts neurodegeneration. Nature Chemical Biology. 9: 586-92. PMID 23873212 DOI: 10.1038/Nchembio.1308 |
0.446 |
|
| 2013 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, et al. Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188le2. PMID 23740897 DOI: 10.1126/Scitranslmed.3005065 |
0.332 |
|
| 2013 |
Serio A, Bilican B, Barmada SJ, Ando DM, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL, Carrasco MA, Phatnani HP, Shum C, Wilmut I, Maniatis T, et al. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy. Proceedings of the National Academy of Sciences of the United States of America. 110: 4697-702. PMID 23401527 DOI: 10.1073/Pnas.1300398110 |
0.444 |
|
| 2012 |
Armakola M, Higgins MJ, Figley MD, Barmada SJ, Scarborough EA, Diaz Z, Fang X, Shorter J, Krogan NJ, Finkbeiner S, Farese RV, Gitler AD. Inhibition of RNA lariat debranching enzyme suppresses TDP-43 toxicity in ALS disease models. Nature Genetics. 44: 1302-9. PMID 23104007 DOI: 10.1038/Ng.2434 |
0.452 |
|
| 2012 |
Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV. Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. The Journal of Clinical Investigation. 122: 3955-9. PMID 23041626 DOI: 10.1172/Jci63113 |
0.405 |
|
| 2012 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, et al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 109: 5803-8. PMID 22451909 DOI: 10.1073/Pnas.1202922109 |
0.495 |
|
| 2010 |
Barmada SJ, Finkbeiner S. Pathogenic TARDBP mutations in amyotrophic lateral sclerosis and frontotemporal dementia: disease-associated pathways. Reviews in the Neurosciences. 21: 251-72. PMID 21086759 DOI: 10.1515/Revneuro.2010.21.4.251 |
0.452 |
|
| 2010 |
Barmada S, Finkbeiner S. Bringing SOD1 into the fold. Nature Neuroscience. 13: 1303-4. PMID 20975748 DOI: 10.1038/Nn1110-1303 |
0.328 |
|
| 2010 |
Barmada SJ, Skibinski G, Korb E, Rao EJ, Wu JY, Finkbeiner S. Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 639-49. PMID 20071528 DOI: 10.1523/Jneurosci.4988-09.2010 |
0.491 |
|
| 2009 |
Jeffrey M, Goodsir C, McGovern G, Barmada SJ, Medrano AZ, Harris DA. Prion protein with an insertional mutation accumulates on axonal and dendritic plasmalemma and is associated with distinctive ultrastructural changes. The American Journal of Pathology. 175: 1208-17. PMID 19700753 DOI: 10.2353/Ajpath.2009.090125 |
0.609 |
|
| 2008 |
Medrano AZ, Barmada SJ, Biasini E, Harris DA. GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice. Neurobiology of Disease. 31: 20-32. PMID 18514536 DOI: 10.1016/J.Nbd.2008.03.006 |
0.599 |
|
| 2007 |
Li A, Piccardo P, Barmada SJ, Ghetti B, Harris DA. Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice. The Embo Journal. 26: 2777-85. PMID 17510630 DOI: 10.1038/Sj.Emboj.7601726 |
0.604 |
|
| 2007 |
Li A, Barmada SJ, Roth KA, Harris DA. N-terminally deleted forms of the prion protein activate both Bax-dependent and Bax-independent neurotoxic pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 852-9. PMID 17251426 DOI: 10.1523/Jneurosci.4244-06.2007 |
0.568 |
|
| 2005 |
Barmada SJ, Harris DA. Visualization of prion infection in transgenic mice expressing green fluorescent protein-tagged prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 5824-32. PMID 15958749 DOI: 10.1523/Jneurosci.1192-05.2005 |
0.566 |
|
| 2004 |
Barmada S, Piccardo P, Yamaguchi K, Ghetti B, Harris DA. GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice. Neurobiology of Disease. 16: 527-37. PMID 15262264 DOI: 10.1016/J.Nbd.2004.05.005 |
0.587 |
|
| 2001 |
Ivanova L, Barmada S, Kummer T, Harris DA. Mutant prion proteins are partially retained in the endoplasmic reticulum. The Journal of Biological Chemistry. 276: 42409-21. PMID 11527974 DOI: 10.1074/Jbc.M106928200 |
0.571 |
|
| Show low-probability matches. |