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Allen A. Thomas, Ph.D. - Publications

Affiliations: 
2000 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2000-2013 Array Biopharma, Inc. 
 2014- Chemistry University of Nebraska at Kearney, Kearney, NE, United States 
Area:
Medicinal Chemistry
Website:
https://thomasresearch.net/
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hall C, Wolfe H, Wells A, Chien HC, Colas C, Schlessinger A, Giacomini KM, Thomas AA. l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan. Bioorganic & Medicinal Chemistry Letters. PMID 31248771 DOI: 10.1016/J.Bmcl.2019.06.033  0.328
2018 Chien HC, Colas C, Finke K, Springer S, Stoner L, Zur AA, Venteicher B, Campbell J, Hall C, Flint A, Augustyn E, Hernandez C, Heeren N, Hansen L, Anthony A, ... ... Thomas AA, et al. Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1). Journal of Medicinal Chemistry. PMID 30048132 DOI: 10.1021/Acs.Jmedchem.8B01007  0.353
2016 Zur AA, Chien HC, Augustyn E, Flint A, Heeren N, Finke K, Hernandez C, Hansen L, Miller S, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA. LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates. Bioorganic & Medicinal Chemistry Letters. PMID 27624080 DOI: 10.1016/J.Bmcl.2016.09.001  0.369
2016 Augustyn E, Finke K, Zur AA, Hansen L, Heeren N, Chien HC, Lin L, Giacomini KM, Colas C, Schlessinger A, Thomas AA. LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs. Bioorganic & Medicinal Chemistry Letters. PMID 27106710 DOI: 10.1016/J.Bmcl.2016.04.023  0.355
2014 Thomas AA, Hunt KW, Volgraf M, Watts RJ, Liu X, Vigers G, Smith D, Sammond D, Tang TP, Rhodes SP, Metcalf AT, Brown KD, Otten JN, Burkard M, Cox AA, et al. Discovery of 7-tetrahydropyran-2-yl chromans: β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors that reduce amyloid β-protein (Aβ) in the central nervous system. Journal of Medicinal Chemistry. 57: 878-902. PMID 24397738 DOI: 10.1021/Jm401635N  0.303
2010 Dupau P, Epple R, Thomas AA, Fokin VV, Sharpless KB. ChemInform Abstract: Osmium-Catalyzed Dihydroxylation of Olefins in Acidic Media: Old Process, New Tricks. Cheminform. 33: no-no. DOI: 10.1002/chin.200244058  0.552
2008 Thomas AA, Le Huerou Y, De Meese J, Gunawardana I, Kaplan T, Romoff TT, Gonzales SS, Condroski K, Boyd SA, Ballard J, Bernat B, DeWolf W, Han M, Lee P, Lemieux C, et al. Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 2206-10. PMID 18267359 DOI: 10.1016/J.Bmcl.2007.11.101  0.302
2008 Le Huerou Y, Gunawardana I, Thomas AA, Boyd SA, de Meese J, Dewolf W, Gonzales SS, Han M, Hayter L, Kaplan T, Lemieux C, Lee P, Pheneger J, Poch G, Romoff TT, et al. Prodrug thiamine analogs as inhibitors of the enzyme transketolase. Bioorganic & Medicinal Chemistry Letters. 18: 505-8. PMID 18083562 DOI: 10.1016/J.Bmcl.2007.11.100  0.317
2002 Dupau P, Epple R, Thomas AA, Fokin VV, Sharpless KB. Osmium-Catalyzed Dihydroxylation of Olefins in Acidic Media: Old Process, New Tricks Advanced Synthesis and Catalysis. 344: 421-433. DOI: 10.1002/1615-4169(200206)344:3/4<421::Aid-Adsc421>3.0.Co;2-F  0.575
1999 Thomas AA, Sharpless KB. The Catalytic Asymmetric Aminohydroxylation of Unsaturated Phosphonates. The Journal of Organic Chemistry. 64: 8379-8385. PMID 11674762 DOI: 10.1021/Jo990060R  0.437
1999 Singleton DA, Merrigan SR, Thomas AA. Stereochemical labeling at natural abundance. Stereochemistry, isotope effects, and mechanism of the Diels-Alder reaction of hexachlorocyclopentadiene with ethyl vinyl ether Tetrahedron Letters. 40: 639-642. DOI: 10.1016/S0040-4039(98)02508-8  0.307
1997 DelMonte AJ, Haller J, Houk KN, Sharpless KB, Singleton DA, Strassner T, Thomas AA. Experimental and theoretical kinetic isotope effects for asymmetric dihydroxylation. Evidence supporting a rate-limiting '(3+2)' cycloaddition Journal of the American Chemical Society. 119: 9907-9908. DOI: 10.1021/Ja971650E  0.409
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