Year |
Citation |
Score |
2023 |
Jenner M, Hai Y, Nguyen HH, Passmore M, Skyrud W, Kim J, Garg NK, Zhang W, Ogorzalek Loo RR, Tang Y. Elucidating the molecular programming of a nonlinear non-ribosomal peptide synthetase responsible for fungal siderophore biosynthesis. Nature Communications. 14: 2832. PMID 37198174 DOI: 10.1038/s41467-023-38484-8 |
0.633 |
|
2022 |
Yang C, Zhang L, Zhang W, Huang C, Zhu Y, Jiang X, Liu W, Zhao M, De BC, Zhang C. Biochemical and structural insights of multifunctional flavin-dependent monooxygenase FlsO1-catalyzed unexpected xanthone formation. Nature Communications. 13: 5386. PMID 36104338 DOI: 10.1038/s41467-022-33131-0 |
0.304 |
|
2020 |
Porterfield WB, Poenateetai N, Zhang W. Engineered Biosynthesis of Alkyne-Tagged Polyketides by Type I PKSs. Iscience. 23: 100938. PMID 32146323 DOI: 10.1016/J.Isci.2020.100938 |
0.348 |
|
2020 |
Li JS, Barber CC, Herman NA, Cai W, Zafrir E, Du Y, Zhu X, Skyrud W, Zhang W. Investigation of secondary metabolism in the industrial butanol hyper-producer Clostridium saccharoperbutylacetonicum N1-4. Journal of Industrial Microbiology & Biotechnology. PMID 32103460 DOI: 10.1007/S10295-020-02266-8 |
0.596 |
|
2020 |
Skyrud W, Flores ADR, Zhang W. Biosynthesis of Cyclohexanecarboxyl-CoA Highlights a Promiscuous Shikimoyl-CoA Synthetase and a FAD-Dependent Dehydratase Acs Catalysis. 10: 3360-3364. DOI: 10.1021/Acscatal.0C00406 |
0.371 |
|
2019 |
Zhang B, Rajakovich LJ, Van Cura D, Blaesi EJ, Mitchell AJ, Tysoe CR, Zhu X, Streit BR, Rui Z, Zhang W, Boal AK, Krebs C, Bollinger JM. Substrate-triggered Formation of a Peroxo-Fe(III/III) Intermediate during Fatty Acid Decarboxylation by UndA. Journal of the American Chemical Society. PMID 31487162 DOI: 10.1021/Jacs.9B06093 |
0.683 |
|
2019 |
Seidel J, Miao Y, Porterfield W, Cai W, Zhu X, Kim SJ, Hu F, Bhattarai-Kline S, Min W, Zhang W. Structure-activity-distribution relationship study of anti-cancer antimycin-type depsipeptides. Chemical Communications (Cambridge, England). PMID 31317975 DOI: 10.1039/C9Cc03051D |
0.566 |
|
2018 |
Su M, Zhu X, Zhang W. Probing the Acyl Carrier Protein-Enzyme Interactions within Terminal Alkyne Biosynthetic Machinery. Aiche Journal. American Institute of Chemical Engineers. 64: 4255-4262. PMID 30983594 DOI: 10.1002/Aic.16355 |
0.592 |
|
2018 |
Twigg FF, Cai W, Huang W, Liu J, Sato M, Perez T, Geng J, Dror M, Montanez I, Tong T, Lee H, Zhang W. Identifying the Biosynthetic Gene Cluster for Triacsins with an N-hydroxytriazene Moiety. Chembiochem : a European Journal of Chemical Biology. PMID 30589194 DOI: 10.1002/Cbic.201800762 |
0.335 |
|
2018 |
Li JS, Barber CC, Zhang W. Natural products from anaerobes. Journal of Industrial Microbiology & Biotechnology. PMID 30284140 DOI: 10.1007/S10295-018-2086-5 |
0.341 |
|
2018 |
Harris N, Born D, Cai W, Huang Y, Martin J, Khalaf R, Drennan C, Zhang W. Isonitrile Formation by a Non-heme Iron(II)-Dependent Oxidase/Decarboxylase. Angewandte Chemie (International Ed. in English). PMID 29906336 DOI: 10.1002/Anie.201804307 |
0.345 |
|
2018 |
Huang C, Yang C, Zhang W, Zhang L, De BC, Zhu Y, Jiang X, Fang C, Zhang Q, Yuan CS, Liu HW, Zhang C. Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines. Nature Communications. 9: 2088. PMID 29802272 DOI: 10.1038/S41467-018-04487-Z |
0.537 |
|
2018 |
Zhu X, Zhang W. Terminal Alkyne Biosynthesis in Marine Microbes. Methods in Enzymology. 604: 89-112. PMID 29779667 DOI: 10.1016/Bs.Mie.2018.01.040 |
0.624 |
|
2018 |
Skyrud W, Liu J, Thankachan D, Cabrera M, Seipke RF, Zhang W. Biosynthesis of the 15-membered ring depsipeptide neoantimycin. Acs Chemical Biology. PMID 29693372 DOI: 10.1021/Acschembio.8B00298 |
0.428 |
|
2017 |
Liu J, Kaganjo J, Zhang W, Zeilstra-Ryalls J. Investigating the bifunctionality of cyclizing and "classical" 5-aminolevulinate synthases. Protein Science : a Publication of the Protein Society. PMID 29027286 DOI: 10.1002/Pro.3324 |
0.421 |
|
2017 |
Cai W, Zhang W. Engineering modular polyketide synthases for production of biofuels and industrial chemicals. Current Opinion in Biotechnology. 50: 32-38. PMID 28946011 DOI: 10.1016/J.Copbio.2017.08.017 |
0.349 |
|
2017 |
Harris NC, Sato M, Herman NA, Twigg F, Cai W, Liu J, Zhu X, Downey J, Khalaf R, Martin J, Koshino H, Zhang W. Biosynthesis of isonitrile lipopeptides by conserved nonribosomal peptide synthetase gene clusters in Actinobacteria. Proceedings of the National Academy of Sciences of the United States of America. PMID 28634299 DOI: 10.1073/Pnas.1705016114 |
0.611 |
|
2016 |
Herman NA, Li J, Bedi R, Turchi B, Liu X, Miller MJ, Zhang W. Development of a High-Efficiency Transformation Method and Implementation of Rational Metabolic Engineering for the Industrial Butanol Hyper-Producer Clostridium saccharoperbutylacetonicum strain N1-4. Applied and Environmental Microbiology. PMID 27836845 DOI: 10.1128/Aem.02942-16 |
0.318 |
|
2016 |
Herman NA, Zhang W. Enzymes for fatty acid-based hydrocarbon biosynthesis. Current Opinion in Chemical Biology. 35: 22-28. PMID 27573483 DOI: 10.1016/J.Cbpa.2016.08.009 |
0.342 |
|
2016 |
Zhu X, Shieh P, Su M, Bertozzi CR, Zhang W. A fluorogenic screening platform enables directed evolution of an alkyne biosynthetic tool. Chemical Communications (Cambridge, England). PMID 27561030 DOI: 10.1039/C6Cc05990B |
0.574 |
|
2016 |
Liu J, Zhu X, Kim SJ, Zhang W. Antimycin-type depsipeptides: discovery, biosynthesis, chemical synthesis, and bioactivities. Natural Product Reports. PMID 27307039 DOI: 10.1039/C6Np00004E |
0.611 |
|
2016 |
Chen Z, Zhang W, Tang X, Fan H, Xie X, Wan Q, Wu X, Tang JZ. Extraction and characterization of polysaccharides from Semen Cassiae by microwave-assisted aqueous two-phase extraction coupled with spectroscopy and HPLC. Carbohydrate Polymers. 144: 263-70. PMID 27083817 DOI: 10.1016/j.carbpol.2016.02.063 |
0.337 |
|
2016 |
Fan W, Ye Y, Chen Z, Shao Y, Xie X, Zhang W, Liu HP, Li C. Metabolic product response profiles of Cherax quadricarinatus towards white spot syndrome virus infection. Developmental and Comparative Immunology. PMID 27068762 DOI: 10.1016/j.dci.2016.04.006 |
0.371 |
|
2016 |
Zhang W, Liu J. Recent Advances in Understanding and Engineering Polyketide Synthesis. F1000research. 5. PMID 26962443 DOI: 10.12688/F1000Research.7326.1 |
0.367 |
|
2016 |
Yang ZH, Chu YM, Zhang W. Accurate approximations for the complete elliptic integral of the second kind Journal of Mathematical Analysis and Applications. 438: 875-888. DOI: 10.1016/j.jmaa.2016.02.035 |
0.36 |
|
2015 |
Fan H, Wu Y, Zhou X, Xia J, Zhang W, Song Y, Liu F, Chen Y, Zhang L, Gao X, Gao H, Li J. Pathway-Based Genome-Wide Association Studies for Two Meat Production Traits in Simmental Cattle. Scientific Reports. 5: 18389. PMID 26672757 DOI: 10.1038/srep18389 |
0.361 |
|
2015 |
Liu J, Zhu X, Zhang W. Identifying the Minimal Enzymes Required for Biosynthesis of Epoxyketone Proteasome Inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 26477320 DOI: 10.1002/Cbic.201500496 |
0.647 |
|
2015 |
Huang W, Kim SJ, Liu J, Zhang W. Identification of the Polyketide Biosynthetic Machinery for the Indolizidine Alkaloid Cyclizidine. Organic Letters. PMID 26473429 DOI: 10.1021/Acs.Orglett.5B02707 |
0.374 |
|
2015 |
Rui Z, Zhang W. Engineering Biosynthesis of Non-ribosomal Peptides and Polyketides by Directed Evolution. Current Topics in Medicinal Chemistry. PMID 26456467 DOI: 10.2174/1568026616666151012112045 |
0.377 |
|
2015 |
Zhu X, Su M, Manickam K, Zhang W. Bacterial Genome Mining of Enzymatic Tools for Alkyne Biosynthesis. Acs Chemical Biology. PMID 26441143 DOI: 10.1021/Acschembio.5B00641 |
0.661 |
|
2015 |
Rui Z, Huang W, Xu F, Han M, Liu X, Lin S, Zhang W. Sparsomycin Biosynthesis Highlights Unusual Module Architecture and Processing Mechanism in Non-ribosomal Peptide Synthetase. Acs Chemical Biology. PMID 26046698 DOI: 10.1021/Acschembio.5B00284 |
0.462 |
|
2015 |
Zhu X, Zhang W. Tagging polyketides/non-ribosomal peptides with a clickable functionality and applications. Frontiers in Chemistry. 3: 11. PMID 25815285 DOI: 10.3389/Fchem.2015.00011 |
0.591 |
|
2015 |
Zhu X, Liu J, Zhang W. De novo biosynthesis of terminal alkyne-labeled natural products. Nature Chemical Biology. 11: 115-20. PMID 25531891 DOI: 10.1038/Nchembio.1718 |
0.621 |
|
2015 |
Liu J, Zhu X, Seipke RF, Zhang W. Biosynthesis of antimycins with a reconstituted 3-formamidosalicylate pharmacophore in Escherichia coli. Acs Synthetic Biology. 4: 559-65. PMID 25275920 DOI: 10.1021/Sb5003136 |
0.646 |
|
2015 |
Rui Z, Harris NC, Zhu X, Huang W, Zhang W. Discovery of a Family of Desaturase-Like Enzymes for 1-Alkene Biosynthesis Acs Catalysis. 5: 7091-7094. DOI: 10.1021/Acscatal.5B01842 |
0.609 |
|
2014 |
Rui Z, Li X, Zhu X, Liu J, Domigan B, Barr I, Cate JH, Zhang W. Microbial biosynthesis of medium-chain 1-alkenes by a nonheme iron oxidase. Proceedings of the National Academy of Sciences of the United States of America. 111: 18237-42. PMID 25489112 DOI: 10.1073/Pnas.1419701112 |
0.636 |
|
2014 |
Liu J, Ng T, Rui Z, Ad O, Zhang W. Unusual acetylation-dependent reaction cascade in the biosynthesis of the pyrroloindole drug physostigmine. Angewandte Chemie (International Ed. in English). 53: 136-9. PMID 24227628 DOI: 10.1002/Anie.201308069 |
0.337 |
|
2013 |
Rui Z, Sandy M, Jung B, Zhang W. Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites Chemistry and Biology. 20: 879-887. PMID 23890006 DOI: 10.1016/J.Chembiol.2013.05.006 |
0.403 |
|
2013 |
Sandy M, Zhu X, Rui Z, Zhang W. Characterization of AntB, a promiscuous acyltransferase involved in antimycin biosynthesis Organic Letters. 15: 3396-3399. PMID 23772837 DOI: 10.1021/Ol4014365 |
0.634 |
|
2012 |
Rui Z, Ye M, Wang S, Fujikawa K, Akerele B, Aung M, Floss HG, Zhang W, Yu TW. Insights into a divergent phenazine biosynthetic pathway governed by a plasmid-born esmeraldin gene cluster. Chemistry & Biology. 19: 1116-25. PMID 22999880 DOI: 10.1016/J.Chembiol.2012.07.025 |
0.372 |
|
2012 |
Sandy M, Rui Z, Gallagher J, Zhang W. Enzymatic synthesis of dilactone scaffold of antimycins Acs Chemical Biology. 7: 1956-1961. PMID 22971101 DOI: 10.1021/Cb300416W |
0.444 |
|
2011 |
Ames BD, Lee MY, Moody C, Zhang W, Tang Y, Tsai SC. Structural and biochemical characterization of ZhuI aromatase/cyclase from the R1128 polyketide pathway. Biochemistry. 50: 8392-406. PMID 21870821 DOI: 10.1021/Bi200593M |
0.762 |
|
2011 |
Walsh CT, Zhang W. Chemical logic and enzymatic machinery for biological assembly of peptidyl nucleoside antibiotics. Acs Chemical Biology. 6: 1000-7. PMID 21851099 DOI: 10.1021/Cb200284P |
0.504 |
|
2011 |
Zhang W, Ntai I, Kelleher NL, Walsh CT. tRNA-dependent peptide bond formation by the transferase PacB in biosynthesis of the pacidamycin group of pentapeptidyl nucleoside antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 108: 12249-53. PMID 21746899 DOI: 10.1073/Pnas.1109539108 |
0.632 |
|
2011 |
Zhang W, Ames BD, Walsh CT. Identification of phenylalanine 3-hydroxylase for meta-tyrosine biosynthesis. Biochemistry. 50: 5401-3. PMID 21615132 DOI: 10.1021/Bi200733C |
0.756 |
|
2011 |
Zhang W, Ntai I, Bolla ML, Malcolmson SJ, Kahne D, Kelleher NL, Walsh CT. Nine enzymes are required for assembly of the pacidamycin group of peptidyl nucleoside antibiotics. Journal of the American Chemical Society. 133: 5240-3. PMID 21417270 DOI: 10.1021/Ja2011109 |
0.762 |
|
2011 |
Qiao K, Zhou H, Xu W, Zhang W, Garg N, Tang Y. A fungal nonribosomal peptide synthetase module that can synthesize thiopyrazines. Organic Letters. 13: 1758-61. PMID 21384820 DOI: 10.1021/Ol200288W |
0.642 |
|
2010 |
Zhang W, Heemstra JR, Walsh CT, Imker HJ. Activation of the pacidamycin PacL adenylation domain by MbtH-like proteins. Biochemistry. 49: 9946-7. PMID 20964365 DOI: 10.1021/Bi101539B |
0.518 |
|
2010 |
Zhang W, Ostash B, Walsh CT. Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 107: 16828-33. PMID 20826445 DOI: 10.1073/Pnas.1011557107 |
0.53 |
|
2010 |
Zhang W, Bolla ML, Kahne D, Walsh CT. A three enzyme pathway for 2-amino-3-hydroxycyclopent-2-enone formation and incorporation in natural product biosynthesis. Journal of the American Chemical Society. 132: 6402-11. PMID 20394362 DOI: 10.1021/Ja1002845 |
0.561 |
|
2010 |
Yan M, Du J, Gu Z, Liang M, Hu Y, Zhang W, Priceman S, Wu L, Zhou ZH, Liu Z, Segura T, Tang Y, Lu Y. A novel intracellular protein delivery platform based on single-protein nanocapsules. Nature Nanotechnology. 5: 48-53. PMID 19935648 DOI: 10.1038/Nnano.2009.341 |
0.397 |
|
2009 |
Gao X, Xie X, Pashkov I, Sawaya MR, Laidman J, Zhang W, Cacho R, Yeates TO, Tang Y. Directed evolution and structural characterization of a simvastatin synthase. Chemistry & Biology. 16: 1064-74. PMID 19875080 DOI: 10.1016/J.Chembiol.2009.09.017 |
0.751 |
|
2009 |
Wang P, Zhang W, Zhan J, Tang Y. Identification of OxyE as an ancillary oxygenase during tetracycline biosynthesis. Chembiochem : a European Journal of Chemical Biology. 10: 1544-50. PMID 19472250 DOI: 10.1002/Cbic.200900122 |
0.515 |
|
2009 |
Zhang W, Tang Y. In vitro analysis of type II polyketide synthase. Methods in Enzymology. 459: 367-93. PMID 19362648 DOI: 10.1016/S0076-6879(09)04616-3 |
0.448 |
|
2008 |
Zhang W, Li Y, Tang Y. Engineered biosynthesis of bacterial aromatic polyketides in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 105: 20683-8. PMID 19075227 DOI: 10.1073/Pnas.0809084105 |
0.698 |
|
2008 |
Zhang W, Watanabe K, Cai X, Jung ME, Tang Y, Zhan J. Identifying the minimal enzymes required for anhydrotetracycline biosynthesis. Journal of the American Chemical Society. 130: 6068-9. PMID 18422316 DOI: 10.1021/Ja800951E |
0.537 |
|
2008 |
Zhang W, Tang Y. Combinatorial biosynthesis of natural products. Journal of Medicinal Chemistry. 51: 2629-33. PMID 18393406 DOI: 10.1021/Jm701269V |
0.43 |
|
2008 |
Ames BD, Korman TP, Zhang W, Smith P, Vu T, Tang Y, Tsai SC. Crystal structure and functional analysis of tetracenomycin ARO/CYC: implications for cyclization specificity of aromatic polyketides. Proceedings of the National Academy of Sciences of the United States of America. 105: 5349-54. PMID 18388203 DOI: 10.1073/Pnas.0709223105 |
0.774 |
|
2008 |
Ma SM, Zhan J, Xie X, Watanabe K, Tang Y, Zhang W. Redirecting the cyclization steps of fungal polyketide synthase. Journal of the American Chemical Society. 130: 38-9. PMID 18072779 DOI: 10.1021/Ja078091O |
0.686 |
|
2007 |
Ma SM, Zhan J, Watanabe K, Xie X, Zhang W, Wang CC, Tang Y. Enzymatic synthesis of aromatic polyketides using PKS4 from Gibberella fujikuroi. Journal of the American Chemical Society. 129: 10642-3. PMID 17696354 DOI: 10.1021/Ja074865P |
0.665 |
|
2007 |
Zhang W, Watanabe K, Wang CC, Tang Y. Investigation of early tailoring reactions in the oxytetracycline biosynthetic pathway. The Journal of Biological Chemistry. 282: 25717-25. PMID 17631493 DOI: 10.1074/Jbc.M703437200 |
0.534 |
|
2007 |
Zhang W, Wilke BI, Zhan J, Watanabe K, Boddy CN, Tang Y. A new mechanism for benzopyrone formation in aromatic polyketide biosynthesis. Journal of the American Chemical Society. 129: 9304-5. PMID 17625867 DOI: 10.1021/Ja0736919 |
0.503 |
|
2006 |
Zhang W, Watanabe K, Wang CC, Tang Y. Heterologous biosynthesis of amidated polyketides with novel cyclization regioselectivity from oxytetracycline polyketide synthase. Journal of Natural Products. 69: 1633-6. PMID 17125237 DOI: 10.1021/Np060290I |
0.501 |
|
2006 |
Zhang W, Ames BD, Tsai SC, Tang Y. Engineered biosynthesis of a novel amidated polyketide, using the malonamyl-specific initiation module from the oxytetracycline polyketide synthase. Applied and Environmental Microbiology. 72: 2573-80. PMID 16597959 DOI: 10.1128/Aem.72.4.2573-2580.2006 |
0.754 |
|
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