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Timothy M Griffin - Publications

Affiliations: 
Oklahoma Medical Research Foundation, USA 
 Duke Medical School, Durham, NC, United States 
 2002 University of California, Berkeley, Berkeley, CA, United States 
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57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fu Y, Batushansky A, Kinter M, Huebner JL, Kraus VB, Griffin TM. Effects of Leptin and Body Weight on Inflammation and Knee Osteoarthritis Phenotypes in Female Rats. Jbmr Plus. 7: e10754. PMID 37457883 DOI: 10.1002/jbm4.10754  0.445
2022 Zhu S, Donovan EL, Makosa D, Mehta-D'souza P, Jopkiewicz A, Batushansky A, Cortassa D, Simmons AD, Lopes EBP, Kinter M, Griffin TM. Sirt3 promotes chondrogenesis, chondrocyte mitochondrial respiration and the development of high-fat diet-induced osteoarthritis in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 36214465 DOI: 10.1002/jbmr.4721  0.776
2022 Kobak KA, Batushansky A, Borowik AK, Lopes EPB, Peelor Iii FF, Donovan EL, Kinter MT, Miller BF, Griffin TM. An In Vivo Stable Isotope Labeling Method to Investigate Individual Matrix Protein Synthesis, Ribosomal Biogenesis, and Cellular Proliferation in Murine Articular Cartilage. Function (Oxford, England). 3: zqac008. PMID 35399495 DOI: 10.1093/function/zqac008  0.718
2020 Griffin TM, Batushansky A, Hudson J, Lopes EBP. Correlation network analysis shows divergent effects of a long-term, high-fat diet and exercise on early stage osteoarthritis phenotypes in mice. Journal of Sport and Health Science. 9: 119-131. PMID 32099720 DOI: 10.1016/j.jshs.2019.05.008  0.32
2020 Griffin TM, Friedman JE. How can parental obesity promote OA across generations? Nature Reviews. Rheumatology. PMID 31949286 DOI: 10.1038/S41584-020-0369-5  0.413
2019 Zhu S, Makosa D, Miller B, Griffin TM. Glutathione as a mediator of cartilage oxidative stress resistance and resilience during aging and osteoarthritis. Connective Tissue Research. 1-14. PMID 31522568 DOI: 10.1080/03008207.2019.1665035  0.389
2019 Yang X, Brobst D, Chan WS, Tse MCL, Herlea-Pana O, Ahuja P, Bi X, Zaw AM, Kwong ZSW, Jia WH, Zhang ZG, Zhang N, Chow SKH, Cheung WH, Louie JCY, ... Griffin TM, et al. Muscle-generated BDNF is a sexually dimorphic myokine that controls metabolic flexibility. Science Signaling. 12. PMID 31409756 DOI: 10.1126/Scisignal.Aau1468  0.337
2019 Kalaitzoglou E, Lopes EBP, Fu Y, Herron JC, Flaming JM, Donovan EL, Hu Y, Filiberti A, Griffin TM, Humphrey MB. TLR4 Promotes and DAP12 Limits Obesity-Induced Osteoarthritis in Aged Female Mice. Jbmr Plus. 3: e10079. PMID 31044181 DOI: 10.1002/jbm4.10079  0.782
2019 Sivasami P, Poudel N, Munteanu MC, Hudson J, Lovern P, Liu L, Griffin T, Hinsdale ME. Adipose tissue loss and lipodystrophy in xylosyltransferase II deficient mice. International Journal of Obesity (2005). PMID 30778123 DOI: 10.1038/S41366-019-0324-1  0.305
2019 Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, ... Griffin TM, et al. Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fibre branching. Journal of Cachexia, Sarcopenia and Muscle. PMID 30706998 DOI: 10.1002/Jcsm.12375  0.728
2019 Zhu S, Donovan E, Lopes E, Kinter M, Simmons A, Makosa D, Cortassa D, West M, Griffin T. Knockdown of sirtuin3 in cartilage protects male mice against high-fat diet-induced osteoarthritis Osteoarthritis and Cartilage. 27: S97-S98. DOI: 10.1016/J.Joca.2019.02.141  0.76
2018 Donovan EL, Lopes EBP, Batushansky A, Kinter M, Griffin TM. Independent effects of dietary fat and sucrose content on chondrocyte metabolism and osteoarthritis pathology in mice. Disease Models & Mechanisms. PMID 30018076 DOI: 10.1242/Dmm.034827  0.78
2018 Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS. Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. Embo Reports. PMID 29420235 DOI: 10.15252/Embr.201745009  0.428
2017 He C, Medley SC, Kim J, Sun C, Kwon HR, Sakashita H, Pincu Y, Yao L, Eppard D, Dai B, Berry WL, Griffin TM, Olson LE. STAT1 modulates tissue wasting or overgrowth downstream from PDGFRβ. Genes & Development. PMID 28924035 DOI: 10.1101/Gad.300384.117  0.304
2017 Issa R, Boeving M, Kinter M, Griffin TM. Effect of biomechanical stress on endogenous antioxidant networks in bovine articular cartilage. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28892196 DOI: 10.1002/Jor.23728  0.696
2017 Kalaitzoglou E, Griffin TM, Humphrey MB. Innate Immune Responses and Osteoarthritis. Current Rheumatology Reports. 19: 45. PMID 28718060 DOI: 10.1007/S11926-017-0672-6  0.316
2017 Barboza E, Hudson J, Chang WP, Kovats S, Towner RA, Silasi-Mansat R, Lupu F, Kent C, Griffin TM. Pro-fibrotic infrapatellar fat pad remodeling without M1-macrophage polarization precedes knee osteoarthritis in diet-induced obese mice. Arthritis & Rheumatology (Hoboken, N.J.). PMID 28141918 DOI: 10.1002/Art.40056  0.772
2017 Barboza E, Kovats T, Hudson J, Kovats S, Griffin T. Exercise induces transient inflammatory and pro-fibrotic remodeling of the infrapatellar fat pad Osteoarthritis and Cartilage. 25: S67. DOI: 10.1016/J.Joca.2017.02.121  0.744
2017 Donovan E, Barboza E, Kinter M, Griffin T. High fat and high sucrose diets in mice have independent effects on osteoarthritis pathology and chondrocyte metabolic stress Osteoarthritis and Cartilage. 25: S65. DOI: 10.1016/J.Joca.2017.02.118  0.743
2016 June RK, Liu-Bryan R, Long F, Griffin TM. Emerging Role of Metabolic Signaling in Synovial Joint Remodeling and Osteoarthritis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27605370 DOI: 10.1002/Jor.23420  0.388
2016 Berenbaum F, Griffin TM, Liu-Bryan R. Metabolic Regulation of Inflammation in Osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 27564539 DOI: 10.1002/Art.39842  0.353
2016 Fu Y, Kinter M, Hudson J, Humphries KM, Lane RS, White JR, Hakim M, Pan Y, Verdin E, Griffin TM. Aging Promotes SIRT3-dependent Cartilage SOD2 Acetylation and Osteoarthritis. Arthritis & Rheumatology (Hoboken, N.J.). PMID 26866626 DOI: 10.1002/Art.39618  0.721
2016 Griffin T. SP0196 Obesity and Diet in Experimental Models of OA Annals of the Rheumatic Diseases. 75: 47.3-47. DOI: 10.1136/Annrheumdis-2016-Eular.6291  0.404
2015 Griffin TM, Humphries KM, Kinter M, Lim HY, Szweda LI. Nutrient sensing and utilization: Getting to the heart of metabolic flexibility. Biochimie. PMID 26476002 DOI: 10.1016/J.Biochi.2015.10.013  0.3
2015 Fu Y, Huebner JL, Kraus VB, Griffin TM. Effect of Aging on Adipose Tissue Inflammation in the Knee Joints of F344BN Rats. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 26450946 DOI: 10.1093/Gerona/Glv151  0.456
2015 Lane RS, Fu Y, Matsuzaki S, Kinter M, Humphries KM, Griffin TM. Mitochondrial respiration and redox coupling in articular chondrocytes. Arthritis Research & Therapy. 17: 54. PMID 25889867 DOI: 10.1186/S13075-015-0566-9  0.719
2014 Zhao Y, Ling F, Griffin TM, He T, Towner R, Ruan H, Sun XH. Up-regulation of the Sirtuin 1 (Sirt1) and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) genes in white adipose tissue of Id1 protein-deficient mice: implications in the protection against diet and age-induced glucose intolerance. The Journal of Biological Chemistry. 289: 29112-22. PMID 25190816 DOI: 10.1074/Jbc.M114.571679  0.43
2014 Yao L, Heuser-Baker J, Herlea-Pana O, Zhang N, Szweda LI, Griffin TM, Barlic-Dicen J. Deficiency in adipocyte chemokine receptor CXCR4 exacerbates obesity and compromises thermoregulatory responses of brown adipose tissue in a mouse model of diet-induced obesity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 4534-50. PMID 25016030 DOI: 10.1096/Fj.14-249797  0.416
2014 Cai A, Hutchison E, Hudson J, Kawashima Y, Komori N, Singh A, Brush RS, Anderson RE, Sonntag WE, Matsumoto H, Griffin TM. Metabolic enrichment of omega-3 polyunsaturated fatty acids does not reduce the onset of idiopathic knee osteoarthritis in mice. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 22: 1301-9. PMID 25008209 DOI: 10.1016/J.Joca.2014.06.033  0.35
2013 Garteiser P, Doblas S, Towner RA, Griffin TM. Calibration of a semi-automated segmenting method for quantification of adipose tissue compartments from magnetic resonance images of mice. Metabolism: Clinical and Experimental. 62: 1686-95. PMID 23890668 DOI: 10.1016/J.Metabol.2013.06.009  0.35
2013 O'Conor CJ, Griffin TM, Liedtke W, Guilak F. Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet. Annals of the Rheumatic Diseases. 72: 300-4. PMID 23178209 DOI: 10.1136/Annrheumdis-2012-202272  0.785
2013 Hutchison E, Hudson J, Roach G, Griffin T. Effect of long-term voluntary exercise on the induction of osteoarthritis by a very high-fat diet in aged mice Osteoarthritis and Cartilage. 21: S64. DOI: 10.1016/J.Joca.2013.02.142  0.309
2013 Hudson J, West M, Fu Y, Griffin T. Leptin signaling and body weight are independent mediators of spontaneous knee osteoarthritis in female rats Osteoarthritis and Cartilage. 21: S53-S54. DOI: 10.1016/J.Joca.2013.02.124  0.446
2012 Roach GC, Edke M, Griffin TM. A novel mouse running wheel that senses individual limb forces: biomechanical validation and in vivo testing. Journal of Applied Physiology (Bethesda, Md. : 1985). 113: 627-35. PMID 22723628 DOI: 10.1152/Japplphysiol.00272.2012  0.307
2012 Issa RI, Griffin TM. Pathobiology of obesity and osteoarthritis: integrating biomechanics and inflammation. Pathobiology of Aging & Age Related Diseases. 2. PMID 22662293 DOI: 10.3402/pba.v2i0.17470  0.742
2012 Griffin TM, Huebner JL, Kraus VB, Yan Z, Guilak F. Induction of osteoarthritis and metabolic inflammation by a very high-fat diet in mice: effects of short-term exercise. Arthritis and Rheumatism. 64: 443-53. PMID 21953366 DOI: 10.1002/Art.33332  0.615
2011 Fu Y, Kinter M, Griffin T. 452 THE EFFECT OF AGING IN CARTILAGE ANTIOXIDANT PROTEIN EXPRESSION AND OSTEOARTHRITIS PROGRESSION IN F344BN RATS Osteoarthritis and Cartilage. 19: S209-S210. DOI: 10.1016/S1063-4584(11)60479-2  0.441
2011 Issa RI, Roach G, Griffin TM. Loading Magnitude, Frequency, and Duration are Important Mediators of Endogenous Antioxidant Activity in Articular Cartilage Free Radical Biology and Medicine. 51: S87. DOI: 10.1016/J.Freeradbiomed.2011.10.403  0.719
2010 Griffin TM, Fermor B, Huebner JL, Kraus VB, Rodriguiz RM, Wetsel WC, Cao L, Setton LA, Guilak F. Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice. Arthritis Research & Therapy. 12: R130. PMID 20604941 DOI: 10.1186/Ar3068  0.606
2010 Costello KE, Guilak F, Setton LA, Griffin TM. Locomotor activity and gait in aged mice deficient for type IX collagen. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 211-8. PMID 20360435 DOI: 10.1152/Japplphysiol.00056.2010  0.536
2010 Griffin TM, DeMoe J, Garteiser P, Doblas S, Towner R. Effect of Wheel Running on Obesity-induced Osteoarthritis in Mice: Systemic versus Local Factors Medicine & Science in Sports & Exercise. 42: 62. DOI: 10.1249/01.Mss.0000389368.75236.Ba  0.366
2009 Griffin TM, Huebner JL, Kraus VB, Guilak F. Extreme obesity due to impaired leptin signaling in mice does not cause knee osteoarthritis. Arthritis and Rheumatism. 60: 2935-44. PMID 19790050 DOI: 10.1002/Art.24854  0.568
2009 Allen KD, Griffin TM, Rodriguiz RM, Wetsel WC, Kraus VB, Huebner JL, Boyd LM, Setton LA. Decreased physical function and increased pain sensitivity in mice deficient for type IX collagen. Arthritis and Rheumatism. 60: 2684-93. PMID 19714629 DOI: 10.1002/Art.24783  0.37
2008 Griffin TM, Guilak F. Why is obesity associated with osteoarthritis? Insights from mouse models of obesity. Biorheology. 45: 387-98. PMID 18836239 DOI: 10.3233/Bir-2008-0485  0.546
2008 Hanna JB, Schmitt D, Griffin TM. The energetic cost of climbing in primates. Science (New York, N.Y.). 320: 898. PMID 18487185 DOI: 10.1126/Science.1155504  0.636
2007 Griffin T, Fermor B, Guilak F. 170 ADIPOKINES AND OSTEOARTHRITIS: SYNERGISTIC EFFECTS OF LEPTIN, FATTY ACIDS AND INTERLEUKIN-1 ON PROTEOGLYCAN BREAKDOWN Osteoarthritis and Cartilage. 15: C102. DOI: 10.1016/S1063-4584(07)61803-2  0.457
2007 Griffin T, Huebner J, Kraus V, Guilak F. 33 EXTREME OBESITY DUE TO IMPAIRED LEPTIN SIGNALING DOES NOT CAUSE OSTEOARTHRITIS IN MICE Osteoarthritis and Cartilage. 15: C32-C33. DOI: 10.1016/S1063-4584(07)61669-0  0.535
2007 Allen K, Griffin T, Wetsel W, Rodriguiz R, Boyd L, Setton L. 3 TYPE IX COLLAGEN KNOCKOUT IS ASSOCIATED WITH ALTERED GAIT BEHAVIORS AND MECHANICAL ALLODYNIA IN MICE Osteoarthritis and Cartilage. 15: C16. DOI: 10.1016/S1063-4584(07)61639-2  0.308
2006 Schmitt D, Cartmill M, Griffin TM, Hanna JB, Lemelin P. Adaptive value of ambling gaits in primates and other mammals. The Journal of Experimental Biology. 209: 2042-9. PMID 16709907 DOI: 10.1242/Jeb.02235  0.629
2006 Griffin TM, Yan Z, Guilak F. Voluntary Exercise and the Development of Osteoarthritis in Mice Fed a High-fat Diet Medicine & Science in Sports & Exercise. 38: S26. DOI: 10.1249/00005768-200611001-00101  0.549
2005 Griffin TM, Guilak F. The role of mechanical loading in the onset and progression of osteoarthritis. Exercise and Sport Sciences Reviews. 33: 195-200. PMID 16239837 DOI: 10.1097/00003677-200510000-00008  0.55
2004 Griffin TM, Kram R, Wickler SJ, Hoyt DF. Biomechanical and energetic determinants of the walk-trot transition in horses. The Journal of Experimental Biology. 207: 4215-23. PMID 15531642 DOI: 10.1242/Jeb.01277  0.524
2003 Griffin TM, Roberts TJ, Kram R. Metabolic cost of generating muscular force in human walking: insights from load-carrying and speed experiments. Journal of Applied Physiology (Bethesda, Md. : 1985). 95: 172-83. PMID 12794096 DOI: 10.1152/Japplphysiol.00944.2002  0.55
2000 Griffin TM, Kram R. Penguin waddling is not wasteful. Nature. 408: 929. PMID 11140670 DOI: 10.1038/35050167  0.535
1999 Griffin TM, Tolani NA, Kram R. Walking in simulated reduced gravity: mechanical energy fluctuations and exchange. Journal of Applied Physiology (Bethesda, Md. : 1985). 86: 383-90. PMID 9887153 DOI: 10.1152/Jappl.1999.86.1.383  0.527
1998 Kram R, Griffin TM, Donelan JM, Chang YH. Force treadmill for measuring vertical and horizontal ground reaction forces. Journal of Applied Physiology (Bethesda, Md. : 1985). 85: 764-9. PMID 9688758 DOI: 10.1152/Jappl.1998.85.2.764  0.682
1998 Griffin T, Tolani N, Kram R. Walking in reduced gravity: Mechanical energy fluctuations Faseb Journal. 12: A679.  0.452
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