| Year |
Citation |
Score |
| 2024 |
Son K, Takhaveev V, Mor V, Yu H, Dillier E, Zilio N, Püllen NJL, Ivanov D, Ulrich HD, Sturla SJ, Schärer OD. Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes. Nature Communications. 15: 1388. PMID 38360910 DOI: 10.1038/s41467-024-45664-7 |
0.547 |
|
| 2023 |
Slyskova J, Muniesa-Vargas A, da Silva IT, Drummond R, Park J, Häckes D, Poetsch I, Ribeiro-Silva C, Moretton A, Heffeter P, Schärer OD, Vermeulen W, Lans H, Loizou JI. Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy. Nar Cancer. 5: zcad057. PMID 38058548 DOI: 10.1093/narcan/zcad057 |
0.546 |
|
| 2023 |
Wie M, Khim KW, Groehler Iv AS, Heo S, Woo J, Son K, Lee EA, Ra JS, Hong SY, Schärer OD, Choi JH, Myung K. Alkylation of nucleobases by 2-chloro--diethylethanamine hydrochloride (CDEAH) sensitizes -deficient tumors. Nar Cancer. 5: zcad042. PMID 37554969 DOI: 10.1093/narcan/zcad042 |
0.491 |
|
| 2023 |
Blee AM, Gallagher KS, Kim HS, Kim M, Troll CR, D'Souza A, Park J, Neufer PD, Schärer OD, Chazin WJ. XPA tumor variants lead to defects in NER that sensitize cells to cisplatin. Biorxiv : the Preprint Server For Biology. PMID 37425789 DOI: 10.1101/2023.06.29.547124 |
0.338 |
|
| 2023 |
Groehler AS, Maratova A, Dao NM, Mahkmut A, Schärer OD. Development of Comprehensive Ultraperformance Liquid Chromatography-High-Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA-DNA Cross-Links. Chemical Research in Toxicology. PMID 37208809 DOI: 10.1021/acs.chemrestox.2c00308 |
0.374 |
|
| 2023 |
Oh JM, Kang Y, Park J, Sung Y, Kim D, Seo Y, Lee EA, Ra JS, Amarsanaa E, Park YU, Lee SY, Hwang JM, Kim H, Schärer O, Cho SW, et al. MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1. Nucleic Acids Research. PMID 37140056 DOI: 10.1093/nar/gkad308 |
0.547 |
|
| 2023 |
van den Heuvel D, Kim M, Wondergem AP, van der Meer PJ, Witkamp M, Lambregtse F, Kim HS, Kan F, Apelt K, Kragten A, González-Prieto R, Vertegaal ACO, Yeo JE, Kim BG, van Doorn R, et al. A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair. Proceedings of the National Academy of Sciences of the United States of America. 120: e2208860120. PMID 36893274 DOI: 10.1073/pnas.2208860120 |
0.807 |
|
| 2023 |
Jaiswal AS, Kim HS, Schärer OD, Sharma N, Williamson EA, Srinivasan G, Phillips L, Kong K, Arya S, Misra A, Dutta A, Gupta Y, Walter CA, Burma S, Narayan S, et al. EEPD1 promotes repair of oxidatively-stressed replication forks. Nar Cancer. 5: zcac044. PMID 36683914 DOI: 10.1093/narcan/zcac044 |
0.332 |
|
| 2023 |
Chung HJ, Lee JR, Kim TM, Kim S, Park K, Kim MJ, Jung E, Kim S, Lee EA, Ra JS, Hwang S, Lee JY, Schärer OD, Kim Y, Myung K, et al. ZNF212 promotes genomic integrity through direct interaction with TRAIP. Nucleic Acids Research. PMID 36594163 DOI: 10.1093/nar/gkac1226 |
0.605 |
|
| 2022 |
Yue Z, Wu F, Guo F, Park J, Wang J, Zhang L, Liao D, Li W, Schärer OD, Lei X. Polycarcin V induces DNA-damage response and enables the profiling of DNA-binding proteins. National Science Review. 9: nwac046. PMID 36601137 DOI: 10.1093/nsr/nwac046 |
0.639 |
|
| 2022 |
Kim M, Kim HS, D'Souza A, Gallagher K, Jeong E, Topolska-Wós A, Ogorodnik Le Meur K, Tsai CL, Tsai MS, Kee M, Tainer JA, Yeo JE, Chazin WJ, Schärer OD. Two interaction surfaces between XPA and RPA organize the preincision complex in nucleotide excision repair. Proceedings of the National Academy of Sciences of the United States of America. 119: e2207408119. PMID 35969784 DOI: 10.1073/pnas.2207408119 |
0.81 |
|
| 2022 |
Blessing C, Apelt K, van den Heuvel D, Gonzalez-Leal C, Rother MB, van der Woude M, González-Prieto R, Yifrach A, Parnas A, Shah RG, Kuo TT, Boer DEC, Cai J, Kragten A, Kim HS, et al. XPC-PARP complexes engage the chromatin remodeler ALC1 to catalyze global genome DNA damage repair. Nature Communications. 13: 4762. PMID 35963869 DOI: 10.1038/s41467-022-31820-4 |
0.575 |
|
| 2022 |
van Toorn M, Turkyilmaz Y, Han S, Zhou D, Kim HS, Salas-Armenteros I, Kim M, Akita M, Wienholz F, Raams A, Ryu E, Kang S, Theil AF, Bezstarosti K, Tresini M, et al. Active DNA damage eviction by HLTF stimulates nucleotide excision repair. Molecular Cell. PMID 35271816 DOI: 10.1016/j.molcel.2022.02.020 |
0.65 |
|
| 2021 |
Aloisi CMN, Escher NA, Kim HS, Geisen SM, Fontana GA, Yeo JE, Schärer OD, Sturla SJ. A combination of direct reversion and nucleotide excision repair counters the mutagenic effects of DNA carboxymethylation. Dna Repair. 110: 103262. PMID 35030424 DOI: 10.1016/j.dnarep.2021.103262 |
0.819 |
|
| 2021 |
Apelt K, Lans H, Schärer OD, Luijsterburg MS. Nucleotide excision repair leaves a mark on chromatin: DNA damage detection in nucleosomes. Cellular and Molecular Life Sciences : Cmls. 78: 7925-7942. PMID 34731255 DOI: 10.1007/s00018-021-03984-7 |
0.622 |
|
| 2021 |
Cheun YK, Groehler AS, Schärer OD. New Synthetic Analogs of Nitrogen Mustard DNA Interstrand Cross-Links and Their Use to Study Lesion Bypass by DNA Polymerases. Chemical Research in Toxicology. 34: 1790-1799. PMID 34133118 DOI: 10.1021/acs.chemrestox.1c00123 |
0.523 |
|
| 2021 |
Tsao N, Schärer OD, Mosammaparast N. The complexity and regulation of repair of alkylation damage to nucleic acids. Critical Reviews in Biochemistry and Molecular Biology. 1-31. PMID 33430640 DOI: 10.1080/10409238.2020.1869173 |
0.543 |
|
| 2021 |
Apelt K, White SM, Kim HS, Yeo JE, Kragten A, Wondergem AP, Rooimans MA, González-Prieto R, Wiegant WW, Lunke S, Flanagan D, Pantaleo S, Quinlan C, Hardikar W, van Attikum H, et al. ERCC1 mutations impede DNA damage repair and cause liver and kidney dysfunction in patients. The Journal of Experimental Medicine. 218. PMID 33315086 DOI: 10.1084/jem.20200622 |
0.839 |
|
| 2020 |
Rageul J, Park JJ, Zeng PP, Lee EA, Yang J, Hwang S, Lo N, Weinheimer AS, Schärer OD, Yeo JE, Kim H. SDE2 integrates into the TIMELESS-TIPIN complex to protect stalled replication forks. Nature Communications. 11: 5495. PMID 33127907 DOI: 10.1038/s41467-020-19162-5 |
0.778 |
|
| 2020 |
Tsutakawa SE, Tsai CL, Yan C, Bralić A, Chazin WJ, Hamdan SM, Schärer OD, Ivanov I, Tainer JA. Envisioning how the prototypic molecular machine TFIIH functions in transcription initiation and DNA repair. Dna Repair. 96: 102972. PMID 33007515 DOI: 10.1016/J.Dnarep.2020.102972 |
0.556 |
|
| 2020 |
Bezalel-Buch R, Cheun YK, Roy U, Schärer OD, Burgers PM. Bypass of DNA interstrand crosslinks by a Rev1-DNA polymerase ζ complex. Nucleic Acids Research. PMID 32633759 DOI: 10.1093/nar/gkaa580 |
0.629 |
|
| 2020 |
Jeong E, Lee SG, Kim HS, Yang J, Shin J, Kim Y, Kim J, Schärer OD, Kim Y, Yeo JE, Kim HM, Cho Y. Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex. Nucleic Acids Research. PMID 32002546 DOI: 10.1093/nar/gkaa062 |
0.723 |
|
| 2020 |
Topolska-Woś AM, Sugitani N, Cordoba JJ, Le Meur KV, Le Meur RA, Kim HS, Yeo JE, Rosenberg D, Hammel M, Schärer OD, Chazin WJ. A key interaction with RPA orients XPA in NER complexes. Nucleic Acids Research. PMID 31925419 DOI: 10.1093/Nar/Gkz1231 |
0.824 |
|
| 2019 |
Raghunandan M, Yeo JE, Walter R, Saito K, Harvey AJ, Ittershagen S, Lee EA, Yang J, Hoatlin ME, Bielinsky AK, Hendrickson EA, Schärer O, Sobeck A. Functional crosstalk between the Fanconi anemia and ATRX/DAXX histone chaperone pathways promotes replication fork recovery. Human Molecular Genetics. PMID 31628488 DOI: 10.1093/hmg/ddz250 |
0.796 |
|
| 2019 |
Srinivasan G, Williamson EA, Kong K, Jaiswal AS, Huang G, Kim HS, Schärer O, Zhao W, Burma S, Sung P, Hromas R. MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers. Proceedings of the National Academy of Sciences of the United States of America. PMID 31395736 DOI: 10.1073/Pnas.1903150116 |
0.33 |
|
| 2019 |
Cheon NY, Kim HS, Yeo JE, Schärer OD, Lee JY. Single-molecule visualization reveals the damage search mechanism for the human NER protein XPC-RAD23B. Nucleic Acids Research. PMID 31372632 DOI: 10.1093/Nar/Gkz629 |
0.847 |
|
| 2019 |
Chazin WJ, Topolska-Woś AM, Sugitani N, Cordoba JJ, Kim HS, Yeo J, Rosenberg D, Hammel M, Schärer OD. Structure of the XPA DNA binding domain and RPA high-affinity DNA binding domains on a model NER substrate Acta Crystallographica Section a Foundations and Advances. 75: a203-a203. DOI: 10.1107/S0108767319098003 |
0.811 |
|
| 2018 |
Mu H, Geacintov NE, Broyde S, Yeo JE, Schärer OD. Molecular basis for damage recognition and verification by XPC-RAD23B and TFIIH in nucleotide excision repair. Dna Repair. PMID 30174301 DOI: 10.1016/J.Dnarep.2018.08.005 |
0.833 |
|
| 2018 |
Jin H, Roy U, Lee G, Schärer OD, Cho Y. Structural Mechanism of DNA Interstrand Cross-link Unhooking by Bacterial FAN1 Nuclease. The Journal of Biological Chemistry. PMID 29514982 DOI: 10.1074/Jbc.Ra118.002171 |
0.577 |
|
| 2017 |
Kato N, Kawasoe Y, Williams H, Coates E, Roy U, Shi Y, Beese LS, Schärer OD, Yan H, Gottesman ME, Takahashi TS, Gautier J. Sensing and Processing of DNA Interstrand Crosslinks by the Mismatch Repair Pathway. Cell Reports. 21: 1375-1385. PMID 29091773 DOI: 10.1016/J.Celrep.2017.10.032 |
0.693 |
|
| 2017 |
Thompson EL, Yeo JE, Lee EA, Kan Y, Raghunandan M, Wiek C, Hanenberg H, Schärer OD, Hendrickson EA, Sobeck A. FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response. Nucleic Acids Research. PMID 29059323 DOI: 10.1093/nar/gkx847 |
0.838 |
|
| 2017 |
Castaño A, Roy U, Schärer OD. Preparation of Stable Nitrogen Mustard DNA Interstrand Cross-Link Analogs for Biochemical and Cell Biological Studies. Methods in Enzymology. 591: 415-431. PMID 28645378 DOI: 10.1016/bs.mie.2017.03.007 |
0.537 |
|
| 2017 |
Beagan K, Armstrong RL, Witsell A, Roy U, Renedo N, Baker AE, Scharer O, McVey M. Drosophila DNA polymerase theta utilizes both helicase-like and polymerase domains during microhomology-mediated end joining and interstrand crosslink repair. Plos Genetics. 13: e1006813. PMID 28542210 DOI: 10.1371/Journal.Pgen.1006813 |
0.654 |
|
| 2017 |
Woodrick J, Gupta S, Camacho S, Parvathaneni S, Choudhury S, Cheema A, Bai Y, Khatkar P, Erkizan HV, Sami F, Su Y, Schärer OD, Sharma S, Roy R. A new sub-pathway of long-patch base excision repair involving 5' gap formation. The Embo Journal. PMID 28373211 DOI: 10.15252/Embj.201694920 |
0.733 |
|
| 2016 |
Pande P, Ji S, Mukherjee S, Schärer OD, Tretyakova NY, Basu AK. Mutagenicity of a model DNA-peptide cross-link in human cells: Roles of translesion synthesis DNA polymerases. Chemical Research in Toxicology. PMID 27951635 DOI: 10.1021/Acs.Chemrestox.6B00397 |
0.718 |
|
| 2016 |
Wickramaratne S, Ji S, Mukherjee S, Su Y, Pence MG, Lior-Hoffmann L, Fu I, Broyde S, Guengerich FP, Distefano M, Scharer OD, Sham YY, Tretyakova N. Bypass of DNA-Protein Cross-links Conjugated to the 7-Deazaguanine Position of DNA by Translesion Synthesis Polymerases. The Journal of Biological Chemistry. PMID 27621316 DOI: 10.1074/Jbc.M116.745257 |
0.792 |
|
| 2016 |
Roy U, Schärer OD. Involvement of translesion synthesis DNA polymerases in DNA interstrand crosslink repair. Dna Repair. PMID 27311543 DOI: 10.1016/J.Dnarep.2016.05.004 |
0.681 |
|
| 2016 |
Roy U, Mukherjee S, Sharma A, Frank EG, Schärer OD. The structure and duplex context of DNA interstrand crosslinks affects the activity of DNA polymerase η. Nucleic Acids Research. PMID 27257072 DOI: 10.1093/Nar/Gkw485 |
0.793 |
|
| 2015 |
Pizzolato J, Mukherjee S, Schärer OD, Jiricny J. FANCD2-associated Nuclease 1, but Not Exonuclease 1 or Flap Endonuclease 1, Is Able to Unhook DNA Interstrand Cross-links in Vitro. The Journal of Biological Chemistry. 290: 22602-11. PMID 26221031 DOI: 10.1074/Jbc.M115.663666 |
0.728 |
|
| 2014 |
Mukherjee S, Guainazzi A, Schärer OD. Synthesis of structurally diverse major groove DNA interstrand crosslinks using three different aldehyde precursors. Nucleic Acids Research. 42: 7429-35. PMID 24782532 DOI: 10.1093/Nar/Gku328 |
0.85 |
|
| 2014 |
Hodskinson MR, Silhan J, Crossan GP, Garaycoechea JI, Mukherjee S, Johnson CM, Schärer OD, Patel KJ. Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair. Molecular Cell. 54: 472-84. PMID 24726326 DOI: 10.1016/J.Molcel.2014.03.014 |
0.791 |
|
| 2014 |
Guillemette S, Branagan A, Peng M, Dhruva A, Schärer OD, Cantor SB. FANCJ localization by mismatch repair is vital to maintain genomic integrity after UV irradiation. Cancer Research. 74: 932-44. PMID 24351291 DOI: 10.1158/0008-5472.Can-13-2474 |
0.617 |
|
| 2013 |
Clauson C, Schärer OD, Niedernhofer L. Advances in understanding the complex mechanisms of DNA interstrand cross-link repair. Cold Spring Harbor Perspectives in Biology. 5: a012732. PMID 24086043 DOI: 10.1101/Cshperspect.A012732 |
0.719 |
|
| 2013 |
Schärer OD. Nucleotide excision repair in eukaryotes. Cold Spring Harbor Perspectives in Biology. 5: a012609. PMID 24086042 DOI: 10.1101/Cshperspect.A012609 |
0.623 |
|
| 2013 |
Wickramaratne S, Mukherjee S, Villalta PW, Schärer OD, Tretyakova NY. Synthesis of sequence-specific DNA-protein conjugates via a reductive amination strategy. Bioconjugate Chemistry. 24: 1496-506. PMID 23885807 DOI: 10.1021/Bc400018U |
0.778 |
|
| 2013 |
Bogliolo M, Schuster B, Stoepker C, Derkunt B, Su Y, Raams A, Trujillo JP, Minguillón J, RamÃrez MJ, Pujol R, Casado JA, Baños R, Rio P, Knies K, Zúñiga S, et al. Mutations in ERCC4, encoding the DNA-repair endonuclease XPF, cause Fanconi anemia. American Journal of Human Genetics. 92: 800-6. PMID 23623386 DOI: 10.1016/J.Ajhg.2013.04.002 |
0.649 |
|
| 2013 |
Slean MM, Reddy K, Wu B, Nichol Edamura K, Kekis M, Nelissen FH, Aspers RL, Tessari M, Schärer OD, Wijmenga SS, Pearson CE. Interconverting conformations of slipped-DNA junctions formed by trinucleotide repeats affect repair outcome. Biochemistry. 52: 773-85. PMID 23339280 DOI: 10.1021/Bi301369B |
0.583 |
|
| 2012 |
Yeo JE, Khoo A, Fagbemi AF, Schärer OD. The efficiencies of damage recognition and excision correlate with duplex destabilization induced by acetylaminofluorene adducts in human nucleotide excision repair. Chemical Research in Toxicology. 25: 2462-8. PMID 23088760 DOI: 10.1021/Tx3003033 |
0.815 |
|
| 2012 |
Knipscheer P, Räschle M, Schärer OD, Walter JC. Replication-coupled DNA interstrand cross-link repair in Xenopus egg extracts. Methods in Molecular Biology (Clifton, N.J.). 920: 221-43. PMID 22941607 DOI: 10.1007/978-1-61779-998-3_16 |
0.676 |
|
| 2012 |
Enoiu M, Ho TV, Long DT, Walter JC, Schärer OD. Construction of plasmids containing site-specific DNA interstrand cross-links for biochemical and cell biological studies. Methods in Molecular Biology (Clifton, N.J.). 920: 203-19. PMID 22941606 DOI: 10.1007/978-1-61779-998-3_15 |
0.833 |
|
| 2012 |
Enoiu M, Jiricny J, Schärer OD. Repair of cisplatin-induced DNA interstrand crosslinks by a replication-independent pathway involving transcription-coupled repair and translesion synthesis. Nucleic Acids Research. 40: 8953-64. PMID 22810206 DOI: 10.1093/Nar/Gks670 |
0.632 |
|
| 2012 |
Schärer OD. Alkyltransferase-like proteins: brokers dealing with alkylated DNA bases. Molecular Cell. 47: 3-4. PMID 22793691 DOI: 10.1016/J.Molcel.2012.06.030 |
0.601 |
|
| 2012 |
Su Y, Orelli B, Madireddy A, Niedernhofer LJ, Schärer OD. Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair. The Journal of Biological Chemistry. 287: 21846-55. PMID 22547097 DOI: 10.1074/Jbc.M111.337899 |
0.871 |
|
| 2012 |
Hentschel S, Alzeer J, Angelov T, Schärer OD, Luedtke NW. Synthesis of DNA interstrand cross-links using a photocaged nucleobase. Angewandte Chemie (International Ed. in English). 51: 3466-9. PMID 22344895 DOI: 10.1002/Anie.201108018 |
0.824 |
|
| 2012 |
Sidorenko VS, Yeo JE, Bonala RR, Johnson F, Schärer OD, Grollman AP. Lack of recognition by global-genome nucleotide excision repair accounts for the high mutagenicity and persistence of aristolactam-DNA adducts. Nucleic Acids Research. 40: 2494-505. PMID 22121226 DOI: 10.1093/Nar/Gkr1095 |
0.815 |
|
| 2012 |
Hentschel S, Alzeer J, Angelov T, Schärer OD, Luedtke NW. Synthese von DNA-Interstrang-Crosslinks unter Verwendung einer photoaktivierbaren Nucleobase Angewandte Chemie. 124: 3523-3526. DOI: 10.1002/Ange.201108018 |
0.846 |
|
| 2011 |
Fu YV, Yardimci H, Long DT, Ho TV, Guainazzi A, Bermudez VP, Hurwitz J, van Oijen A, Schärer OD, Walter JC. Selective bypass of a lagging strand roadblock by the eukaryotic replicative DNA helicase. Cell. 146: 931-41. PMID 21925316 DOI: 10.1016/J.Cell.2011.07.045 |
0.856 |
|
| 2011 |
Ho TV, Guainazzi A, Derkunt SB, Enoiu M, Schärer OD. Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases. Nucleic Acids Research. 39: 7455-64. PMID 21666254 DOI: 10.1093/Nar/Gkr448 |
0.861 |
|
| 2011 |
Fagbemi AF, Orelli B, Schärer OD. Regulation of endonuclease activity in human nucleotide excision repair. Dna Repair. 10: 722-9. PMID 21592868 DOI: 10.1016/J.Dnarep.2011.04.022 |
0.853 |
|
| 2011 |
Schärer OD. Multistep damage recognition, pathway coordination and connections to transcription, damage signaling, chromatin structure, cancer and aging: current perspectives on the nucleotide excision repair pathway. Dna Repair. 10: 667. PMID 21561812 DOI: 10.1016/J.Dnarep.2011.04.017 |
0.43 |
|
| 2010 |
Guainazzi A, Campbell AJ, Angelov T, Simmerling C, Schärer OD. Synthesis and molecular modeling of a nitrogen mustard DNA interstrand crosslink. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 12100-3. PMID 20842675 DOI: 10.1002/Chem.201002041 |
0.814 |
|
| 2010 |
Guainazzi A, Schärer OD. Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy. Cellular and Molecular Life Sciences : Cmls. 67: 3683-97. PMID 20730555 DOI: 10.1007/S00018-010-0492-6 |
0.871 |
|
| 2010 |
Ho TV, Schärer OD. Translesion DNA synthesis polymerases in DNA interstrand crosslink repair. Environmental and Molecular Mutagenesis. 51: 552-66. PMID 20658647 DOI: 10.1002/Em.20573 |
0.834 |
|
| 2010 |
Ahmad A, Enzlin JH, Bhagwat NR, Wijgers N, Raams A, Appledoorn E, Theil AF, J Hoeijmakers JH, Vermeulen W, J Jaspers NG, Schärer OD, Niedernhofer LJ. Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients. Plos Genetics. 6: e1000871. PMID 20221251 DOI: 10.1371/Journal.Pgen.1000871 |
0.585 |
|
| 2010 |
Orelli B, McClendon TB, Tsodikov OV, Ellenberger T, Niedernhofer LJ, Schärer OD. The XPA-binding domain of ERCC1 is required for nucleotide excision repair but not other DNA repair pathways. The Journal of Biological Chemistry. 285: 3705-12. PMID 19940136 DOI: 10.1074/Jbc.M109.067538 |
0.859 |
|
| 2010 |
Schärer OD, Campbell AJ. Mechanisms of Base Excision Repair and Nucleotide Excision Repair The Chemical Biology of Dna Damage. 239-260. DOI: 10.1002/9783527630110.ch11 |
0.409 |
|
| 2009 |
Knipscheer P, Räschle M, Smogorzewska A, Enoiu M, Ho TV, Schärer OD, Elledge SJ, Walter JC. The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair. Science (New York, N.Y.). 326: 1698-701. PMID 19965384 DOI: 10.1126/Science.1182372 |
0.82 |
|
| 2009 |
Staresincic L, Fagbemi AF, Enzlin JH, Gourdin AM, Wijgers N, Dunand-Sauthier I, Giglia-Mari G, Clarkson SG, Vermeulen W, Schärer OD. Coordination of dual incision and repair synthesis in human nucleotide excision repair. The Embo Journal. 28: 1111-20. PMID 19279666 DOI: 10.1038/Emboj.2009.49 |
0.866 |
|
| 2009 |
Schärer OD, Campbell AJ. Wedging out DNA damage. Nature Structural & Molecular Biology. 16: 102-4. PMID 19190661 DOI: 10.1038/Nsmb0209-102 |
0.686 |
|
| 2009 |
Angelov T, Guainazzi A, Schärer OD. Generation of DNA interstrand cross-links by post-synthetic reductive amination. Organic Letters. 11: 661-4. PMID 19132933 DOI: 10.1021/Ol802719A |
0.845 |
|
| 2009 |
Schärer OD. Structure-specific endonucleases in DNA repair Chimia. 63: 753-757. DOI: 10.2533/chimia.2009.753 |
0.665 |
|
| 2009 |
Räschle M, Knipscheer P, Enoiu M, Angelov T, Sun J, Griffith JD, Ellenberger TE, Schärer OD, Walter JC. Mechanism of Replication-Coupled DNA Interstrand Crosslink Repair (DOI:10.1016/j.cell.2008.08.030) Cell. 137: 972. DOI: 10.1016/J.Cell.2009.05.009 |
0.609 |
|
| 2008 |
Schärer OD. XPG: its products and biological roles. Advances in Experimental Medicine and Biology. 637: 83-92. PMID 19181113 DOI: 10.1007/978-0-387-09599-8_9 |
0.426 |
|
| 2008 |
Räschle M, Knipscheer P, Knipsheer P, Enoiu M, Angelov T, Sun J, Griffith JD, Ellenberger TE, Schärer OD, Walter JC. Mechanism of replication-coupled DNA interstrand crosslink repair. Cell. 134: 969-80. PMID 18805090 DOI: 10.1016/J.Cell.2008.08.030 |
0.713 |
|
| 2008 |
Krasikova YS, Rechkunova NI, Maltseva EA, Petruseva IO, Silnikov VN, Zatsepin TS, Oretskaya TS, Scharer OD, Lavrik OI. Interaction of nucleotide excision repair factors XPC-HR23B, XPA, and RPA with damaged DNA. Biochemistry. 73: 886-896. PMID 18774935 DOI: 10.1134/S0006297908080063 |
0.708 |
|
| 2008 |
Maltseva EA, Rechkunova NI, Petruseva IO, Vermeulen W, Schärer OD, Lavrik OI. Crosslinking of nucleotide excision repair proteins with DNA containing photoreactive damages. Bioorganic Chemistry. 36: 77-84. PMID 18191172 DOI: 10.1016/J.Bioorg.2007.11.004 |
0.689 |
|
| 2008 |
Schärer OD. Hot topics in DNA repair: the molecular basis for different disease states caused by mutations in TFIIH and XPG. Dna Repair. 7: 339-44. PMID 18077223 DOI: 10.1016/J.Dnarep.2007.10.007 |
0.408 |
|
| 2008 |
Schärer OD. A molecular basis for damage recognition in eukaryotic nucleotide excision repair. Chembiochem : a European Journal of Chemical Biology. 9: 21-3. PMID 18033706 DOI: 10.1002/Cbic.200700619 |
0.499 |
|
| 2007 |
Schärer OD. Achieving broad substrate specificity in damage recognition by binding accessible nondamaged DNA. Molecular Cell. 28: 184-6. PMID 17964258 DOI: 10.1016/J.Molcel.2007.10.006 |
0.657 |
|
| 2007 |
Tsodikov OV, Ivanov D, Orelli B, Staresincic L, Shoshani I, Oberman R, Schärer OD, Wagner G, Ellenberger T. Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA. The Embo Journal. 26: 4768-76. PMID 17948053 DOI: 10.1038/Sj.Emboj.7601894 |
0.859 |
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| 2007 |
Hohl M, Dunand-Sauthier I, Staresincic L, Jaquier-Gubler P, Thorel F, Modesti M, Clarkson SG, Schärer OD. Domain swapping between FEN-1 and XPG defines regions in XPG that mediate nucleotide excision repair activity and substrate specificity. Nucleic Acids Research. 35: 3053-63. PMID 17452369 DOI: 10.1093/nar/gkm092 |
0.302 |
|
| 2007 |
Maltseva EA, Rechkunova NI, Gillet LC, Petruseva IO, Schärer OD, Lavrik OI. Crosslinking of the NER damage recognition proteins XPC-HR23B, XPA and RPA to photoreactive probes that mimic DNA damages. Biochimica Et Biophysica Acta. 1770: 781-9. PMID 17320292 DOI: 10.1016/J.Bbagen.2007.01.007 |
0.698 |
|
| 2006 |
Alzeer J, Schärer OD. A modified thymine for the synthesis of site-specific thymine-guanine DNA interstrand crosslinks. Nucleic Acids Research. 34: 4458-66. PMID 16945959 DOI: 10.1093/Nar/Gkl587 |
0.802 |
|
| 2006 |
Igoucheva O, Alexeev V, Scharer O, Yoon K. Involvement of ERCC1/XPF and XPG in oligodeoxynucleotide-directed gene modification. Oligonucleotides. 16: 94-104. PMID 16584298 DOI: 10.1089/oli.2006.16.94 |
0.562 |
|
| 2006 |
Gillet LC, Schärer OD. Molecular mechanisms of mammalian global genome nucleotide excision repair. Chemical Reviews. 106: 253-76. PMID 16464005 DOI: 10.1021/Cr040483F |
0.37 |
|
| 2006 |
Schärer OD. DNA Damage Recognition. Edited by Wolfram Siede, Yoke Wah Kow and Paul W. Doetsch. Chembiochem. 7: 1458-1458. DOI: 10.1002/Cbic.200600328 |
0.644 |
|
| 2005 |
Tsodikov OV, Enzlin JH, Schärer OD, Ellenberger T. Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1. Proceedings of the National Academy of Sciences of the United States of America. 102: 11236-41. PMID 16076955 DOI: 10.1073/Pnas.0504341102 |
0.555 |
|
| 2005 |
Gillet LC, Alzeer J, Schärer OD. Site-specific incorporation of N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (dG-AAF) into oligonucleotides using modified 'ultra-mild' DNA synthesis. Nucleic Acids Research. 33: 1961-9. PMID 15814813 DOI: 10.1093/Nar/Gki335 |
0.852 |
|
| 2005 |
Schärer OD. DNA interstrand crosslinks: natural and drug-induced DNA adducts that induce unique cellular responses. Chembiochem : a European Journal of Chemical Biology. 6: 27-32. PMID 15637664 DOI: 10.1002/Cbic.200400287 |
0.605 |
|
| 2005 |
Dunand-Sauthier I, Hohl M, Thorel F, Jaquier-Gubler P, Clarkson SG, Schärer OD. The spacer region of XPG mediates recruitment to nucleotide excision repair complexes and determines substrate specificity. The Journal of Biological Chemistry. 280: 7030-7. PMID 15590680 DOI: 10.1074/Jbc.M412228200 |
0.415 |
|
| 2004 |
Tapias A, Auriol J, Forget D, Enzlin JH, Schärer OD, Coin F, Coulombe B, Egly JM. Ordered conformational changes in damaged DNA induced by nucleotide excision repair factors. The Journal of Biological Chemistry. 279: 19074-83. PMID 14981083 DOI: 10.1074/Jbc.M312611200 |
0.69 |
|
| 2003 |
Schärer OD. Chemistry and biology of DNA repair. Angewandte Chemie (International Ed. in English). 42: 2946-74. PMID 12851945 DOI: 10.1002/Anie.200200523 |
0.711 |
|
| 2003 |
Hohl M, Thorel F, Clarkson SG, Schärer OD. Structural determinants for substrate binding and catalysis by the structure-specific endonuclease XPG. The Journal of Biological Chemistry. 278: 19500-8. PMID 12644470 DOI: 10.1074/Jbc.M213155200 |
0.653 |
|
| 2003 |
Schärer OD. Chemie und Biologie der DNA-Reparatur Angewandte Chemie. 115: 3052-3082. DOI: 10.1002/Ange.200200523 |
0.648 |
|
| 2002 |
Gillet LC, Schärer OD. Preparation of C8-amine and acetylamine adducts of 2'-deoxyguanosine suitably protected for DNA synthesis. Organic Letters. 4: 4205-8. PMID 12443059 DOI: 10.1021/Ol026474F |
0.474 |
|
| 2002 |
Godthelp BC, Wiegant WW, van Duijn-Goedhart A, Schärer OD, van Buul PP, Kanaar R, Zdzienicka MZ. Mammalian Rad51C contributes to DNA cross-link resistance, sister chromatid cohesion and genomic stability. Nucleic Acids Research. 30: 2172-82. PMID 12000837 DOI: 10.1093/Nar/30.10.2172 |
0.595 |
|
| 2002 |
Enzlin JH, Schärer OD. The active site of the DNA repair endonuclease XPF-ERCC1 forms a highly conserved nuclease motif. The Embo Journal. 21: 2045-53. PMID 11953324 DOI: 10.1093/Emboj/21.8.2045 |
0.576 |
|
| 2001 |
Schärer OD, Jiricny J. Recent progress in the biology, chemistry and structural biology of DNA glycosylases Bioessays. 23: 270-281. PMID 11223884 DOI: 10.1002/1521-1878(200103)23:3<270::Aid-Bies1037>3.0.Co;2-J |
0.664 |
|
| 2001 |
Schärer OD. Chemical biology of mammalian DNA repair Chimia. 55: 340-344. |
0.642 |
|
| 1999 |
Barrett TE, Schärer OD, Savva R, Brown T, Jiricny J, Verdine GL, Pearl LH. Crystal structure of a thwarted mismatch glycosylase DNA repair complex. The Embo Journal. 18: 6599-609. PMID 10581234 DOI: 10.1093/Emboj/18.23.6599 |
0.577 |
|
| 1999 |
Bennink ML, Schärer OD, Kanaar R, Sakata-Sogawa K, Schins JM, Kanger JS, De Grooth BG, Greve J. Single-molecule manipulation of double-stranded DNA using optical tweezers: Interaction studies of DNA with RecA and YOYO-1 Cytometry. 36: 200-208. PMID 10404969 DOI: 10.1002/(SICI)1097-0320(19990701)36:3<200::AID-CYTO9>3.0.CO;2-T |
0.5 |
|
| 1998 |
Lau AY, Schärer OD, Samson L, Verdine GL, Ellenberger T. Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision. Cell. 95: 249-58. PMID 9790531 DOI: 10.1016/S0092-8674(00)81755-9 |
0.599 |
|
| 1998 |
Erzberger JP, Barsky D, Schärer OD, Colvin ME, Wilson DM. Elements in abasic site recognition by the major human and Escherichia coli apurinic/apyrimidinic endonucleases. Nucleic Acids Research. 26: 2771-8. PMID 9592167 DOI: 10.1093/Nar/26.11.2771 |
0.547 |
|
| 1998 |
Schärer OD, Nash HM, Jiricny J, Laval J, Verdine GL. Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases. The Journal of Biological Chemistry. 273: 8592-7. PMID 9535832 DOI: 10.1074/Jbc.273.15.8592 |
0.617 |
|
| 1997 |
Schärer OD, Deng L, Verdine GL. Chemical approaches toward understanding base excision DNA repair. Current Opinion in Chemical Biology. 1: 526-31. PMID 9667887 DOI: 10.1016/S1367-5931(97)80048-8 |
0.641 |
|
| 1997 |
McCullough AK, Dodson ML, Schärer OD, Lloyd RS. The role of base flipping in damage recognition and catalysis by T4 endonuclease V. The Journal of Biological Chemistry. 272: 27210-7. PMID 9341165 DOI: 10.1074/jbc.272.43.27210 |
0.448 |
|
| 1997 |
Schärer OD, Kawate T, Gallinari P, Jiricny J, Verdine GL. Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 94: 4878-83. PMID 9144158 DOI: 10.1073/Pnas.94.10.4878 |
0.619 |
|
| 1997 |
Deng L, Scharer OD, Verdine GL. Unusually strong binding of a designed transition-state analog to a base-excision DNA repair protein Journal of the American Chemical Society. 119: 7865-7866. DOI: 10.1021/Ja970828U |
0.541 |
|
| 1996 |
McCullough AK, Schärer O, Verdine GL, Lloyd RS. Structural determinants for specific recognition by T4 endonuclease V. The Journal of Biological Chemistry. 271: 32147-52. PMID 8943268 DOI: 10.1074/Jbc.271.50.32147 |
0.506 |
|
| 1996 |
Nash HM, Bruner SD, Schärer OD, Kawate T, Addona TA, Spooner E, Lane WS, Verdine GL. Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. Current Biology : Cb. 6: 968-80. PMID 8805338 DOI: 10.1016/S0960-9822(02)00641-3 |
0.658 |
|
| 1996 |
Labahn J, Schärer OD, Long A, Ezaz-Nikpay K, Verdine GL, Ellenberger TE. Structural basis for the excision repair of alkylation-damaged DNA. Cell. 86: 321-9. PMID 8706136 DOI: 10.1016/S0092-8674(00)80103-8 |
0.664 |
|
| 1995 |
Schärer OD, Verdine GL. A designed inhibitor of base-excision DNA repair Journal of the American Chemical Society. 117: 10781-10782. DOI: 10.1021/Ja00148A036 |
0.594 |
|
| 1995 |
Schärer OD, Ortholand JY, Ganesan A, Ezaz-Nikpay K, Verdine GL. Specific binding of the DNA repair enzyme AlkA to a pyrrolidine-based inhibitor Journal of the American Chemical Society. 117: 6623-6624. DOI: 10.1021/Ja00129A039 |
0.568 |
|
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