Ashley M. Laughney, Ph.D. - Publications

Affiliations: 
2012 Engineering Dartmouth College, Hanover, NH, United States 
Area:
Biomedical, Optics

33/60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ganesh K, Basnet H, Kaygusuz Y, Laughney A, He L, Sharma R, O'Rourke K, Reuter V, Huang Y, Masilionis I, Turkekul M, Er E, Manova-Todorova K, Saltz L, Weiser M, et al. Abstract A12: L1CAM defines the regenerative origin of metastasis initiating cells in colorectal cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-A12  0.326
2018 Xie XP, Laks DR, Sun D, Poran A, Laughney AM, Belenguer G, Massague J, Zhou X, Farinas I, Elemento O, Parada LF. Abstract 3015: Precise investigation of cancer stem cells in mouse glioblastoma Cancer Research. 78: 3015-3015. DOI: 10.1158/1538-7445.Am2018-3015  0.319
2016 Laughney AM, Malladi S, Macalinao D, Massagué J. Abstract A01: Investigating clonal heterogeneity and transcriptional vulnerabilities in latent metastasis Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-A01  0.348
2015 Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Science Translational Medicine. 7: 314ra183. PMID 26582898 DOI: 10.1126/Scitranslmed.Aac6522  0.345
2015 Fernandez-Barreras G, Real E, Laughney AM, Krishnaswamy V, Paulsen KD, Lopez-Higuera JM, Pogue BW, Conde OM. Multispectral reflectance enhancement for breast cancer visualization in the operating room Progress in Biomedical Optics and Imaging - Proceedings of Spie. 9311. DOI: 10.1117/12.2078774  0.634
2014 Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R. Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Science Translational Medicine. 6: 261ra152. PMID 25378644 DOI: 10.1126/Scitranslmed.3009318  0.307
2013 Laughney AM, Krishnaswamy V, Rizzo EJ, Schwab MC, Barth RJ, Cuccia DJ, Tromberg BJ, Paulsen KD, Pogue BW, Wells WA. Spectral discrimination of breast pathologies in situ using spatial frequency domain imaging. Breast Cancer Research : Bcr. 15: R61. PMID 23915805 DOI: 10.1186/Bcr3455  0.668
2013 Eguizabal A, Laughney AM, García-Allende PB, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM. Direct identification of breast cancer pathologies using blind separation of label-free localized reflectance measurements. Biomedical Optics Express. 4: 1104-18. PMID 23847736 DOI: 10.1364/Boe.4.001104  0.63
2013 Laughney AM, Krishnaswamy V, Rice TB, Cuccia DJ, Barth RJ, Tromberg BJ, Paulsen KD, Pogue BW, Wells WA. System analysis of spatial frequency domain imaging for quantitative mapping of surgically resected breast tissues. Journal of Biomedical Optics. 18: 036012. PMID 23525360 DOI: 10.1117/1.Jbo.18.3.036012  0.611
2013 Krishnaswamy V, Laughney AM, Wells WA, Paulsen KD, Pogue BW. Scanning in situ spectroscopy platform for imaging surgical breast tissue specimens. Optics Express. 21: 2185-94. PMID 23389199 DOI: 10.1364/Oe.21.002185  0.634
2013 Eguizabal A, Laughney AM, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM. Fractal analysis of scatter imaging signatures to distinguish breast pathologies Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8592. DOI: 10.1117/12.2003830  0.611
2013 Eguizabal A, Laughney AM, Garcia Allende PB, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM. Linear classifier and textural analysis of optical scattering images for tumor classification during breast cancer extraction Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8592. DOI: 10.1117/12.2003814  0.64
2012 Laughney AM, Krishnaswamy V, Rizzo EJ, Schwab MC, Barth RJ, Pogue BW, Paulsen KD, Wells WA. Scatter spectroscopic imaging distinguishes between breast pathologies in tissues relevant to surgical margin assessment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 6315-25. PMID 22908098 DOI: 10.1158/1078-0432.Ccr-12-0136  0.669
2012 Pogue B, Laughney A, Krishnaswamy V, Wells W, Paulsen KD. Multi-spectral Morphology Scanning for Margin Detection in Breast Surgery Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2012.Bw3B.1  0.579
2012 Laughney AM, Krishnaswamy V, Paulsen KD, Pogue BW, Rizzo EJ, Barth RJ, Wells WA. Abstract 3670: Spectroscopy imaging platform differentiates pathology diagnoses in breast surgical specimens Cancer Research. 72: 3670-3670. DOI: 10.1158/1538-7445.Am2012-3670  0.654
2012 Eguizabal A, Laughney AM, Allende PBG, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM. Enhanced tumor contrast during breast lumpectomy provided by independent component analysis of localized reflectance measures Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8230. DOI: 10.1117/12.909348  0.583
2012 Eguizabal A, Laughney AM, Allende PBG, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM. Blind breast tissue diagnosis using independent component analysis of localized backscattering response Progress in Biomedical Optics and Imaging - Proceedings of Spie. 8230. DOI: 10.1117/12.909326  0.651
2012 Eguizabal A, Laughney AM, García-Allende PB, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM. Textural analysis of optical scattering for identification of cancer in breast surgical specimens Proceedings - International Symposium On Biomedical Imaging. 1615-1618. DOI: 10.1109/ISBI.2012.6235885  0.597
2012 Eguizabal A, Laughney AM, García-Allende PB, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM. ICA-guided delineation of breast cancer pathology Proceedings - International Symposium On Biomedical Imaging. 1611-1614. DOI: 10.1109/ISBI.2012.6235884  0.552
2011 Krishnaswamy V, Laughney AM, Paulsen KD, Pogue BW. Dark-field scanning in situ spectroscopy platform for broadband imaging of resected tissue. Optics Letters. 36: 1911-3. PMID 21593932 DOI: 10.1364/Ol.36.001911  0.614
2011 Isabelle M, Klubben W, He T, Laughney AM, Glaser A, Krishnaswamy V, Hoopes PJ, Hasan T, Pogue BW. Assessment of biophysical tumor response to PDT in pancreatic cancer using localized reflectance spectroscopy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7886. DOI: 10.1117/12.876147  0.684
2011 Krishnaswamy V, Laughney AM, Paulsen KD, Pogue BW. A dark-field scanning spectroscopy platform for localized scatter and fluorescence imaging of tissue Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7907. DOI: 10.1117/12.875462  0.619
2011 Laughney A, Krishnaswamy V, Wells WA, Conde OM, Paulsen KD, Pogue BW. Optical assessment of pathology in surgically resected tissues Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7907. DOI: 10.1117/12.874059  0.627
2010 Laughney AM, Krishnaswamy V, Garcia-Allende PB, Conde OM, Wells WA, Paulsen KD, Pogue BW. Automated classification of breast pathology using local measures of broadband reflectance. Journal of Biomedical Optics. 15: 066019. PMID 21198193 DOI: 10.1117/1.3516594  0.603
2010 Krishnaswamy V, Laughney AM, Samkoe KS, Wells WA, Paulsen KD, Pogue BW. Broadband Scatter Spectroscopy Imager for Breast Tumor Margin Delineation Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2010.Bwb5  0.626
2010 Laughney AM, Krishnaswamy V, Garcia-Allende PB, Wells WA, Conde OM, Paulsen KD, Pogue BW. Imaging Breast Pathology in situ Using Broadband Scatter Spectroscopy and a K-Nearest Neighbor Classifier Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2010.Bwb3  0.64
2009 Jiang S, Pogue BW, Laughney AM, Kogel CA, Paulsen KD. Measurement of pressure-displacement kinetics of hemoglobin in normal breast tissue with near-infrared spectral imaging. Applied Optics. 48: D130-6. PMID 19340100 DOI: 10.1364/Ao.48.00D130  0.563
2009 Pogue BW, Krishnaswamy V, Laughney A, Paulsen KD, Hoopes PJ, Allende PBG. Spectral scatter scanning system for surgical margin detection Head & Neck Oncology. 1. DOI: 10.1186/1758-3284-1-S1-O12  0.504
2009 Krishnaswamy V, Wells WA, Laughney AM, Samkoe KS, Pogue BW. A multi-spectral, dark-field, reflectance microscope for Tumor margin delineation during breast lumpectomy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7187. DOI: 10.1117/12.809193  0.482
2009 Laughney A, Krishnaswamy V, Schwab M, Wells WA, Paulsen KD, Pogue BW. Biophysical interpretation and ex-vivo characterization of scattered light from tumor-associated breast stroma Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7174. DOI: 10.1117/12.808323  0.446
2008 Jiang S, Pogue BW, Laughney AM, Paulsen KD. Pressure-Enhanced Near-Infrared Breast Imaging of Normal Subjects Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2008.Bsue17  0.591
2008 Pogue BW, Li Z, Carpenter C, Laughney A, Krishnaswamy V, Davis SC, Jiang S, Paulsen KD. System design for spectrally encoded video-rate near infrared tomography during magnetic resonance imaging of the breast Proceedings of Spie. 6850. DOI: 10.1117/12.778326  0.642
2008 Jiang S, Pogue BW, Laughney AM, Paulsen KD. Pressure-enhanced near-infrared breast imaging of normal subjects Biomedical Optics, Biomed 2008. BSuE17.  0.409
Low-probability matches (unlikely to be authored by this person)
2015 Laughney AM, Elizalde S, Genovese G, Bakhoum SF. Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution. Cell Reports. 12: 809-20. PMID 26212324 DOI: 10.1016/J.Celrep.2015.06.065  0.294
2018 Elizalde S, Laughney AM, Bakhoum SF. A Markov chain for numerical chromosomal instability in clonally expanding populations. Plos Computational Biology. 14: e1006447. PMID 30204765 DOI: 10.1371/Journal.Pcbi.1006447  0.288
2020 Laughney AM, Hu J, Campbell NR, Bakhoum SF, Setty M, Lavallée VP, Xie Y, Masilionis I, Carr AJ, Kottapalli S, Allaj V, Mattar M, Rekhtman N, Xavier JB, Mazutis L, et al. Regenerative lineages and immune-mediated pruning in lung cancer metastasis. Nature Medicine. PMID 32042191 DOI: 10.1038/S41591-019-0750-6  0.287
2020 Wang R, Sharma R, Shen X, Laughney AM, Funato K, Clark PJ, Shpokayte M, Morgenstern P, Navare M, Xu Y, Harbi S, Masilionis I, Nanjangud G, Yang Y, Duran-Rehbein G, et al. Adult Human Glioblastomas Harbor Radial Glia-like Cells. Stem Cell Reports. PMID 32004492 DOI: 10.1016/J.Stemcr.2020.01.007  0.281
2009 Jiang S, Pogue BW, Laughney AM, Keith DP. Pressure-enhanced near-infrared breast imaging: Towards cancer patient imaging Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7174. DOI: 10.1117/12.808071  0.278
2018 Xie X, Laks D, Sun D, Poran A, Laughney A, Belenguer G, Massague J, Zhou X, Farinas I, Elemento O, Parada L. TMOD-36. PRECISE INVESTIGATION OF CANCER STEM CELLS IN A MOUSE GLIOBLASTOMA MODEL Neuro-Oncology. 20: vi276-vi276. DOI: 10.1093/Neuonc/Noy148.1148  0.278
2014 Sprachman MM, Laughney AM, Kohler RH, Weissleder R. In vivo imaging of multidrug resistance using a third generation MDR1 inhibitor. Bioconjugate Chemistry. 25: 1137-42. PMID 24806886 DOI: 10.1021/Bc500154C  0.261
2019 Santos CP, Lapi E, Martínez de Villarreal J, Álvaro-Espinosa L, Fernández-Barral A, Barbáchano A, Domínguez O, Laughney AM, Megías D, Muñoz A, Real FX. Urothelial organoids originating from Cd49f mouse stem cells display Notch-dependent differentiation capacity. Nature Communications. 10: 4407. PMID 31562298 DOI: 10.1038/S41467-019-12307-1  0.251
2015 Bakhoum SF, Kabeche L, Wood MD, Laucius CD, Qu D, Laughney AM, Reynolds GE, Louie RJ, Phillips J, Chan DA, Zaki BI, Murnane JP, Petritsch C, Compton DA. Numerical chromosomal instability mediates susceptibility to radiation treatment. Nature Communications. 6: 5990. PMID 25606712 DOI: 10.1038/Ncomms6990  0.245
2013 Agasti SS, Laughney AM, Kohler RH, Weissleder R. A photoactivatable drug-caged fluorophore conjugate allows direct quantification of intracellular drug transport. Chemical Communications (Cambridge, England). 49: 11050-2. PMID 24135896 DOI: 10.1039/C3Cc46089D  0.23
2023 Bhardwaj P, Iyengar NM, Zahid H, Carter KM, Byun DJ, Choi MH, Sun Q, Savenkov O, Louka C, Liu C, Piloco P, Acosta M, Bareja R, Elemento O, Foronda M, ... ... Laughney AM, et al. Obesity promotes breast epithelium DNA damage in women carrying a germline mutation in . Science Translational Medicine. 15: eade1857. PMID 36812344 DOI: 10.1126/scitranslmed.ade1857  0.229
2016 Taunk NK, Laughney A, Ghossein R, Lee N, Chung C, Bakhoum SF. The Relationship of Numerical Chromosomal Instability With Clinical Characteristics and Outcomes in Head and Neck Cancers Treated With Multimodality Therapy. International Journal of Radiation Oncology, Biology, Physics. 96: E594. PMID 27675110 DOI: 10.1016/J.Ijrobp.2016.06.2117  0.224
2018 Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, et al. Chromosomal instability drives metastasis through a cytosolic DNA response. Nature. PMID 29342134 DOI: 10.1038/Nature25432  0.222
2018 Ganesh K, Basnet H, O'Rourke KP, Laughney AM, He L, Batlle E, Lowe SW, Pe'er D, Shia J, Massague J. Abstract 4990: Regenerative origin of colorectal metastasis stem cells Tumor Biology. DOI: 10.1158/1538-7445.Am2018-4990  0.216
2023 Li J, Hubisz MJ, Earlie EM, Duran MA, Hong C, Varela AA, Lettera E, Deyell M, Tavora B, Havel JJ, Phyu SM, Amin AD, Budre K, Kamiya E, Cavallo JA, ... ... Laughney AM, et al. Non-cell-autonomous cancer progression from chromosomal instability. Nature. PMID 37612508 DOI: 10.1038/s41586-023-06464-z  0.213
2015 Laughney A, Murnane J, Genovese G, Elizalde S, Compton D, Kabeche L, Spratt D, Zaki B, Bakhoum S. Targeting the Process of Mitotic Chromosome Segregation as a Novel Sensitizing Target to Radiation Treatment International Journal of Radiation Oncology*Biology*Physics. 93: S50. DOI: 10.1016/J.Ijrobp.2015.07.122  0.209
2022 Li Z, Low V, Luga V, Sun J, Earlie E, Parang B, Shobana Ganesh K, Cho S, Endress J, Schild T, Hu M, Lyden D, Jin W, Guo C, Dephoure N, ... ... Laughney AM, et al. Tumor-produced and aging-associated oncometabolite methylmalonic acid promotes cancer-associated fibroblast activation to drive metastatic progression. Nature Communications. 13: 6239. PMID 36266345 DOI: 10.1038/s41467-022-33862-0  0.18
2020 Ganesh K, Basnet H, Kaygusuz Y, Laughney AM, He L, Sharma R, O'Rourke KP, Reuter VP, Huang YH, Turkekul M, Emrah E, Masilionis I, Manova-Todorova K, Weiser MR, Saltz LB, et al. L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer. Nature Cancer. 1: 28-45. PMID 32656539 DOI: 10.1038/s43018-019-0006-x  0.174
2021 Bakhoum MF, Francis JH, Agustinus A, Earlie EM, Di Bona M, Abramson DH, Duran M, Masilionis I, Molina E, Shoushtari AN, Goldbaum MH, Mischel PS, Bakhoum SF, Laughney AM. Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression. Nature Communications. 12: 5402. PMID 34518527 DOI: 10.1038/s41467-021-25529-z  0.153
2021 Deyell M, Garris CS, Laughney AM. Cancer metastasis as a non-healing wound. British Journal of Cancer. PMID 33731858 DOI: 10.1038/s41416-021-01309-w  0.152
2023 Adler FR, Anderson ARA, Bhushan A, Bogdan P, Bravo-Cordero JJ, Brock A, Chen Y, Cukierman E, DelGiorno KE, Denis GV, Ferrall-Fairbanks MC, Gartner ZJ, Germain RN, Gordon DM, Hunter G, ... ... Laughney AM, et al. Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell Systems. 14: 252-257. PMID 37080161 DOI: 10.1016/j.cels.2023.03.002  0.133
2022 Ganesh K, Basnet H, Kaygusuz Y, Laughney AM, He L, Sharma R, O'Rourke KP, Reuter VP, Huang YH, Turkekul M, Er EE, Masilionis I, Manova-Todorova K, Weiser MR, Saltz LB, et al. Author Correction: L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer. Nature Cancer. 1: 1128. PMID 35122071 DOI: 10.1038/s43018-020-00130-3  0.125
2024 Rogava M, Aprati TJ, Chi WY, Melms JC, Hug C, Davis SH, Earlie EM, Chung C, Deshmukh SK, Wu S, Sledge G, Tang S, Ho P, Amin AD, Caprio L, ... ... Laughney AM, et al. Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation. Nature Cancer. PMID 38286827 DOI: 10.1038/s43018-023-00704-x  0.124
2020 Xie XP, Laks DR, Sun D, Poran A, Laughney AM, Wang Z, Sam J, Belenguer G, Fariñas I, Elemento O, Zhou X, Parada LF. High-resolution mouse subventricular zone stem-cell niche transcriptome reveals features of lineage, anatomy, and aging. Proceedings of the National Academy of Sciences of the United States of America. PMID 33229571 DOI: 10.1073/pnas.2014389117  0.12
2024 Gardner EE, Earlie EM, Li K, Thomas J, Hubisz MJ, Stein BD, Zhang C, Cantley LC, Laughney AM, Varmus H. Lineage-specific intolerance to oncogenic drivers restricts histological transformation. Science (New York, N.Y.). 383: eadj1415. PMID 38330136 DOI: 10.1126/science.adj1415  0.109
2020 Wang R, Sharma R, Shen X, Laughney AM, Funato K, Clark PJ, Shpokayte M, Morgenstern P, Navare M, Xu Y, Harbi S, Masilionis I, Nanjangud G, Yang Y, Duran-Rehbein G, et al. Adult Human Glioblastomas Harbor Radial Glia-like Cells. Stem Cell Reports. 15: 275-277. PMID 32668221 DOI: 10.1016/j.stemcr.2020.06.002  0.054
2020 Haynes K, Yau C, Bild A, Laughney A, Morsut L, Yang X, Zaugg J, Hsu P, Pancaldi V, Iyer-Biswas S. How Has the COVID-19 Pandemic Changed How You Will Approach Research and Lab Work in the Future? Cell Systems. 11: 550-554. PMID 33333028 DOI: 10.1016/j.cels.2020.11.011  0.032
Hide low-probability matches.