Timothy A. Thornton, Ph.D. - Publications

Affiliations: 
2005 University of Chicago, Chicago, IL 
Area:
Statistics, Genetics

89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Gaynor SM, Joseph T, Bai X, Zou Y, Boutkov B, Maxwell EK, Delaneau O, Hofmeister RJ, Krasheninina O, Balasubramanian S, Marcketta A, Backman J, Reid JG, Overton JD, Lotta LA, ... ... Thornton TA, et al. Yield of genetic association signals from genomes, exomes and imputation in the UK Biobank. Nature Genetics. PMID 39322778 DOI: 10.1038/s41588-024-01930-4  0.36
2024 Sun KY, Bai X, Chen S, Bao S, Zhang C, Kapoor M, Backman J, Joseph T, Maxwell E, Mitra G, Gorovits A, Mansfield A, Boutkov B, Gokhale S, Habegger L, ... ... Thornton T, et al. A deep catalogue of protein-coding variation in 983,578 individuals. Nature. PMID 38768635 DOI: 10.1038/s41586-024-07556-0  0.334
2024 Grinde KE, Browning BL, Reiner AP, Thornton TA, Browning SR. Adjusting for principal components can induce spurious associations in genome-wide association studies in admixed populations. Biorxiv : the Preprint Server For Biology. PMID 38617337 DOI: 10.1101/2024.04.02.587682  0.377
2023 Ziyatdinov A, Torres J, Alegre-Díaz J, Backman J, Mbatchou J, Turner M, Gaynor SM, Joseph T, Zou Y, Liu D, Wade R, Staples J, Panea R, Popov A, Bai X, ... ... Thornton TA, et al. Genotyping, sequencing and analysis of 140,000 adults from Mexico City. Nature. PMID 37821707 DOI: 10.1038/s41586-023-06595-3  0.352
2023 Horimoto ARVR, Boyken LA, Blue EE, Grinde KE, Nafikov RA, Sohi HK, Nato AQ, Bis JC, Brusco LI, Morelli L, Ramirez A, Dalmasso MC, Temple S, Satizabal C, Browning SR, ... ... Thornton TA, et al. Admixture mapping implicates 13q33.3 as ancestry-of-origin locus for Alzheimer disease in Hispanic and Latino populations. Hgg Advances. 4: 100207. PMID 37333771 DOI: 10.1016/j.xhgg.2023.100207  0.354
2022 Taub MA, Conomos MP, Keener R, Iyer KR, Weinstock JS, Yanek LR, Lane J, Miller-Fleming TW, Brody JA, Raffield LM, McHugh CP, Jain D, Gogarten SM, Laurie CA, Keramati A, ... ... Thornton T, et al. Genetic determinants of telomere length from 109,122 ancestrally diverse whole-genome sequences in TOPMed. Cell Genomics. 2. PMID 35530816 DOI: 10.1016/j.xgen.2021.100084  0.411
2021 Horimoto A, Xue D, Cai J, Lash J, Daviglus M, Franceschini N, Thornton T. Genome-Wide Admixture Mapping of Estimated Glomerular Filtration Rate and Chronic Kidney Disease Identify European and African Ancestry-of-Origin Loci in Hispanic and Latino Individuals in the United States. Journal of the American Society of Nephrology : Jasn. PMID 34670813 DOI: 10.1681/ASN.2021050617  0.358
2021 Mikhaylova AV, McHugh CP, Polfus LM, Raffield LM, Boorgula MP, Blackwell TW, Brody JA, Broome J, Chami N, Chen MH, Conomos MP, Cox C, Curran JE, Daya M, Ekunwe L, ... ... Thornton TA, et al. Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program. American Journal of Human Genetics. PMID 34582791 DOI: 10.1016/j.ajhg.2021.08.007  0.388
2021 Little A, Hu Y, Sun Q, Jain D, Broome J, Chen MH, Thibord F, McHugh C, Surendran P, Blackwell TW, Brody JA, Bhan A, Chami N, Vries PS, Ekunwe L, ... ... Thornton T, et al. Whole genome sequence analysis of platelet traits in the NHLBI trans-omics for precision medicine initiative. Human Molecular Genetics. PMID 34553764 DOI: 10.1093/hmg/ddab252  0.321
2021 Lin E, Tsai SJ, Kuo PH, Liu YL, Yang AC, Conomos MP, Thornton TA. Genome-wide association study in the Taiwan biobank identifies four novel genes for human height: NABP2, RASA2, RNF41 and SLC39A5. Human Molecular Genetics. PMID 34270706 DOI: 10.1093/hmg/ddab202  0.403
2021 Horimoto ARVR, Xue D, Thornton TA, Blue EE. Admixture mapping reveals the association between Native American ancestry at 3q13.11 and reduced risk of Alzheimer's disease in Caribbean Hispanics. Alzheimer's Research & Therapy. 13: 122. PMID 34217363 DOI: 10.1186/s13195-021-00866-9  0.322
2021 Sofer T, Zheng X, Laurie CA, Gogarten SM, Brody JA, Conomos MP, Bis JC, Thornton TA, Szpiro A, O'Connell JR, Lange EM, Gao Y, Cupples LA, Psaty BM, et al. Variant-specific inflation factors for assessing population stratification at the phenotypic variance level. Nature Communications. 12: 3506. PMID 34108454 DOI: 10.1038/s41467-021-23655-2  0.368
2021 Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, ... ... Thornton TA, et al. Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 590: 290-299. PMID 33568819 DOI: 10.1038/s41586-021-03205-y  0.356
2020 Keys KL, Mak ACY, White MJ, Eckalbar WL, Dahl AW, Mefford J, Mikhaylova AV, Contreras MG, Elhawary JR, Eng C, Hu D, Huntsman S, Oh SS, Salazar S, Lenoir MA, ... ... Thornton TA, et al. On the cross-population generalizability of gene expression prediction models. Plos Genetics. 16: e1008927. PMID 32797036 DOI: 10.1371/Journal.Pgen.1008927  0.379
2020 Leavitt C, Zakai NA, Auer P, Cushman M, Lange EM, Levitan EB, Olson N, Thornton TA, Tracy RP, Wilson JG, Lange LA, Reiner AP, Raffield LM. Interferon gamma-induced protein 10 (IP-10) and cardiovascular disease in African Americans. Plos One. 15: e0231013. PMID 32240245 DOI: 10.1371/Journal.Pone.0231013  0.305
2020 Raffield LM, Lu AT, Szeto MD, Little A, Grinde KE, Shaw J, Auer PL, Cushman M, Horvath S, Irvin MR, Lange EM, Lange LA, Nickerson DA, Thornton TA, Wilson JG, et al. Coagulation factor VIII: Relationship to Cardiovascular Disease Risk and Whole Genome Sequence and Epigenome-Wide Analysis in African Americans. Journal of Thrombosis and Haemostasis : Jth. PMID 31985870 DOI: 10.1111/Jth.14741  0.35
2019 Kowalski MH, Qian H, Hou Z, Rosen JD, Tapia AL, Shan Y, Jain D, Argos M, Arnett DK, Avery C, Barnes KC, Becker LC, Bien SA, Bis JC, Blangero J, ... ... Thornton TA, et al. Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations. Plos Genetics. 15: e1008500. PMID 31869403 DOI: 10.1371/Journal.Pgen.1008500  0.519
2019 Blue EE, Horimoto ARVR, Mukherjee S, Wijsman EM, Thornton TA. Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31606368 DOI: 10.1016/J.Jalz.2019.07.016  0.312
2019 Dalton R, Lee SB, Claw KG, Prasad B, Phillips BR, Shen DD, Hong Wong L, Fade M, McDonald MG, Dunham MJ, Fowler DM, Rettie AE, Schuetz E, Thornton TA, Nickerson DA, et al. Interrogation of CYP2D6 structural variant alleles improves the correlation between CYP2D6 genotype and CYP2D6-mediated metabolic activity. Clinical and Translational Science. PMID 31536170 DOI: 10.1111/Cts.12695  0.374
2019 Gogarten SM, Sofer T, Chen H, Yu C, Brody JA, Thornton TA, Rice KM, Conomos MP. Genetic association testing using the GENESIS R/Bioconductor package. Bioinformatics (Oxford, England). PMID 31329242 DOI: 10.1093/Bioinformatics/Btz567  0.395
2019 Swenson BR, Louie T, Lin HJ, Méndez-Giráldez R, Below JE, Laurie CC, Kerr KF, Highland H, Thornton TA, Ryckman KK, Kooperberg C, Soliman EZ, Seyerle AA, Guo X, Taylor KD, et al. GWAS of QRS duration identifies new loci specific to Hispanic/Latino populations. Plos One. 14: e0217796. PMID 31251759 DOI: 10.1371/Journal.Pone.0217796  0.46
2019 Wojcik GL, Graff M, Nishimura KK, Tao R, Haessler J, Gignoux CR, Highland HM, Patel YM, Sorokin EP, Avery CL, Belbin GM, Bien SA, Cheng I, Cullina S, Hodonsky CJ, ... ... Thornton TA, et al. Genetic analyses of diverse populations improves discovery for complex traits. Nature. PMID 31217584 DOI: 10.1038/S41586-019-1310-4  0.475
2019 Thomson RJ, McMorran B, Hoy W, Jose M, Whittock L, Thornton T, Burgio G, Mathews JD, Foote S. New Genetic Loci Associated With Chronic Kidney Disease in an Indigenous Australian Population. Frontiers in Genetics. 10: 330. PMID 31040861 DOI: 10.3389/Fgene.2019.00330  0.47
2019 Mikhaylova AV, Thornton TA. Accuracy of Gene Expression Prediction From Genotype Data With PrediXcan Varies Across and Within Continental Populations. Frontiers in Genetics. 10: 261. PMID 31001318 DOI: 10.3389/Fgene.2019.00261  0.4
2019 Cade BE, Chen H, Stilp AM, Louie T, Ancoli-Israel S, Arens R, Barfield R, Below JE, Cai J, Conomos MP, Evans DS, Frazier-Wood AC, Gharib SA, Gleason KJ, Gottlieb DJ, ... ... Thornton TA, et al. Associations of variants In the hexokinase 1 and interleukin 18 receptor regions with oxyhemoglobin saturation during sleep. Plos Genetics. 15: e1007739. PMID 30990817 DOI: 10.1371/Journal.Pgen.1007739  0.434
2019 Henderson LM, Robinson RF, Ray L, Li T, Dillard DA, Schilling BD, Mosley M, Janssen PL, Fohner AE, Rettie AE, Thummel KE, Thornton TA, Veenstra DL. VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People. Clinical and Translational Science. PMID 30821933 DOI: 10.1111/Cts.12611  0.315
2019 Grinde KE, Brown LA, Reiner AP, Thornton TA, Browning SR. Genome-wide Significance Thresholds for Admixture Mapping Studies. American Journal of Human Genetics. PMID 30773276 DOI: 10.1016/J.Ajhg.2019.01.008  0.438
2018 Wang H, Cade BE, Sofer T, Sands SA, Chen H, Browning S, Stilp AM, Louie TL, Thornton TA, Craig Johnson W, Below JE, Conomos MP, Evans DS, Gharib SA, Guo X, et al. Admixture mapping identifies novel loci for obstructive sleep apnea in hispanic/latino americans. Human Molecular Genetics. PMID 30403821 DOI: 10.1093/Hmg/Ddy387  0.453
2018 Grinde KE, Qi Q, Thornton TA, Liu S, Shadyab AH, Chan KHK, Reiner AP, Sofer T. Generalizing polygenic risk scores from Europeans to Hispanics/Latinos. Genetic Epidemiology. PMID 30368908 DOI: 10.1002/Gepi.22166  0.457
2018 Workalemahu T, Enquobahrie DA, Gelaye B, Thornton TA, Tekola-Ayele F, Sanchez SE, Garcia PJ, Palomino HG, Hajat A, Romero R, Ananth CV, Williams MA. Abruptio Placentae Risk and Genetic Variations in Mitochondrial Biogenesis and Oxidative Phosphorylation: Replication of a Candidate Gene Association Study. American Journal of Obstetrics and Gynecology. PMID 30194050 DOI: 10.1016/J.Ajog.2018.08.042  0.386
2018 Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Thornton TA, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/S41380-018-0112-7  0.425
2018 Workalemahu T, Enquobahrie DA, Gelaye B, Sanchez SE, Garcia PJ, Tekola-Ayele F, Hajat A, Thornton TA, Ananth CV, Williams MA. Genetic variations and risk of placental abruption: A genome-wide association study and meta-analysis of genome-wide association studies. Placenta. 66: 8-16. PMID 29884306 DOI: 10.1016/J.Placenta.2018.04.008  0.461
2018 Nafikov RA, Nato AQ, Sohi H, Wang B, Brown L, Horimoto AR, Vardarajan BN, Barral SM, Tosto G, Mayeux RP, Thornton TA, Blue E, Wijsman EM. Analysis of pedigree data in populations with multiple ancestries: Strategies for dealing with admixture in Caribbean Hispanic families from the ADSP. Genetic Epidemiology. PMID 29862559 DOI: 10.1002/Gepi.22133  0.447
2018 Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj A, Thornton T, DeStefano A, Martin E, Wang LS, Brown L, et al. Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. 5: 406-417. PMID 29688227 DOI: 10.1002/Acn3.537  0.343
2018 Bhatt DK, Basit A, Zhang H, Gaedigk A, Lee SB, Claw KG, Mehrotra A, Chaudhry AS, Pearce RE, Gaedigk R, Broeckel U, Thornton TA, Nickerson DA, Schuetz EG, Amory J, et al. Hepatic Abundance and Activity of Androgen and Drug Metabolizing Enzyme, UGT2B17, are Associated with Genotype, Age, and Sex. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29602798 DOI: 10.1124/Dmd.118.080952  0.363
2018 Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, ... ... Thornton TA, et al. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dementia and Geriatric Cognitive Disorders. 45: 1-17. PMID 29486463 DOI: 10.1159/000485503  0.327
2018 Khan BA, Robinson R, Fohner AE, Muzquiz LI, Schilling BD, Beans JA, Olnes MJ, Trawicki L, Frydenlund H, Laukes C, Beatty P, Phillips B, Nickerson D, Howlett K, Dillard DA, ... Thornton TA, et al. Cytochrome P450 Genetic Variation Associated with Tamoxifen Biotransformation in American Indian and Alaska Native People. Clinical and Translational Science. PMID 29436156 DOI: 10.1111/Cts.12542  0.368
2018 Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj AC, Thornton TA, Destefano AL, Martin ER, Wang L, Brown L, et al. P1-156: Gene-Based Analyses In Whole Genome Sequencing Of Familial Late-Onset Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.160  0.342
2018 Wessels ME, Crane PK, Mez J, Trittschuh EH, Saykin AJ, Fardo DW, Thornton TA, Gibbons LE, Sanders RE, Mukherjee S. P1-141: Genome-Wide Analyses Of Isolated Relative Cognitive Impairments Identifies Suggestive Hits In Five Studies Alzheimers & Dementia. 14: 329. DOI: 10.1016/J.Jalz.2018.06.144  0.305
2017 Sofer T, Baier LJ, Browning SR, Thornton TA, Talavera GA, Wassertheil-Smoller S, Daviglus ML, Hanson R, Kobes S, Cooper RS, Cai J, Levy D, Reiner AP, Franceschini N. Admixture mapping in the Hispanic Community Health Study/Study of Latinos reveals regions of genetic associations with blood pressure traits. Plos One. 12: e0188400. PMID 29155883 DOI: 10.1371/Journal.Pone.0188400  0.432
2017 Chen H, Cade BE, Gleason KJ, Bjonnes AC, Stilp AM, Sofer T, Conomos MP, Ancoli-Israel S, Arens R, Azarbarzin A, Bell GI, Below JE, Chun S, Evans DS, Ewert R, ... ... Thornton TA, et al. Multi-ethnic Meta-analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea Related Quantitative Trait Locus in Men. American Journal of Respiratory Cell and Molecular Biology. PMID 29077507 DOI: 10.1165/Rcmb.2017-0237Oc  0.414
2017 Blue EE, Yu CE, Thornton TA, Chapman NH, Kernfeld E, Jiang N, Shively KM, Buckingham KJ, Marvin CT, Bamshad MJ, Bird TD, Wijsman EM. Variants regulating ZBTB4 are associated with age-at-onset of Alzheimer's disease. Genes, Brain, and Behavior. PMID 29045054 DOI: 10.1111/Gbb.12429  0.376
2017 Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, ... ... Thornton TA, et al. Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications. 8: 16140. PMID 28767105 DOI: 10.1038/Ncomms16140  0.353
2017 Zhan X, Zhao N, Plantinga A, Thornton TA, Conneely KN, Epstein MP, Wu MC. Powerful Genetic Association Analysis for Common or Rare Variants with High Dimensional Structured Traits. Genetics. PMID 28642271 DOI: 10.1534/Genetics.116.199646  0.471
2017 Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, ... ... Thornton TA, et al. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nature Communications. 8: 15805. PMID 28613276 DOI: 10.1038/Ncomms15805  0.439
2017 Kerr KF, Avery CL, Lin HJ, Raffield LM, Zhang QS, Browning BL, Browning SR, Conomos MP, Gogarten SM, Laurie CC, Sofer T, Thornton TA, Hohensee C, Jackson RD, Kooperberg C, et al. Genome-wide Association Study of Heart Rate and Its Variability in Hispanic/Latino Cohorts. Heart Rhythm. PMID 28610988 DOI: 10.1016/J.Hrthm.2017.06.018  0.379
2017 Hodonsky CJ, Jain D, Schick UM, Morrison JV, Brown L, McHugh CP, Schurmann C, Chen DD, Liu YM, Auer PL, Laurie CA, Taylor KD, Browning BL, Li Y, Papanicolaou G, ... ... Thornton TA, et al. Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos. Plos Genetics. 13: e1006760. PMID 28453575 DOI: 10.1371/Journal.Pgen.1006760  0.47
2017 Raffield LM, Louie T, Sofer T, Jain D, Ipp E, Taylor KD, Papanicolaou GJ, Avilés-Santa L, Lange LA, Laurie CC, Conomos MP, Thornton TA, Ida Chen YD, Qi Q, Cotler S, et al. Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): Potential genomic intersection of iron and glucose regulation? Human Molecular Genetics. PMID 28334935 DOI: 10.1093/Hmg/Ddx082  0.333
2017 Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, ... ... Thornton T, et al. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28183528 DOI: 10.1016/J.Jalz.2016.12.012  0.407
2017 Jain D, Hodonsky CJ, Schick UM, Morrison JV, Minnerath S, Brown L, Schurmann C, Liu Y, Auer PL, Laurie CA, Taylor KD, Browning B, Papanicolaou G, Browning S, Loos RJ, ... ... Thornton TA, et al. Genome-Wide Association of White Blood Cell Counts in Hispanic/Latino Americans: The Hispanic Community Health Study/Study of Latinos. Human Molecular Genetics. PMID 28158719 DOI: 10.1093/Hmg/Ddx024  0.487
2017 Brown LA, Sofer T, Stilp AM, Baier LJ, Kramer HJ, Masindova I, Levy D, Hanson RL, Moncrieft AE, Redline S, Rosas SE, Lash JP, Cai J, Laurie CC, Browning S, ... Thornton T, et al. Admixture Mapping Identifies an Amerindian Ancestry Locus Associated with Albuminuria in Hispanics in the United States. Journal of the American Society of Nephrology : Jasn. PMID 28137830 DOI: 10.1681/Asn.2016091010  0.476
2017 Sofer T, Heller R, Bogomolov M, Avery CL, Graff M, North KE, Reiner AP, Thornton TA, Rice K, Benjamini Y, Laurie CC, Kerr KF. A powerful statistical framework for generalization testing in GWAS, with application to the HCHS/SOL. Genetic Epidemiology. PMID 28090672 DOI: 10.1002/Gepi.22029  0.458
2016 Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR, Sun F, Evans DS, Li X, Li J, Smith AV, Bis JC, Brody JA, ... ... Thornton TA, et al. A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Journal of Medical Genetics. PMID 28039329 DOI: 10.1136/Jmedgenet-2016-104112  0.377
2016 Blue EM, Brown LA, Conomos MP, Kirk JL, Nato AQ, Popejoy AB, Raffa J, Ranola J, Wijsman EM, Thornton T. Estimating relationships between phenotypes and subjects drawn from admixed families. Bmc Proceedings. 10: 357-362. PMID 27980662 DOI: 10.1186/S12919-016-0056-3  0.366
2016 Saad M, Nato AQ, Grimson FL, Lewis SM, Brown LA, Blue EM, Thornton TA, Thompson EA, Wijsman EM. Identity-by-descent estimation with population- and pedigree-based imputation in admixed family data. Bmc Proceedings. 10: 295-301. PMID 27980652 DOI: 10.1186/S12919-016-0046-5  0.388
2016 Kramer HJ, Stilp AM, Laurie CC, Reiner AP, Lash J, Daviglus ML, Rosas SE, Ricardo AC, Tayo BO, Flessner MF, Kerr KF, Peralta C, Durazo-Arvizu R, Conomos M, Thornton T, et al. African Ancestry-Specific Alleles and Kidney Disease Risk in Hispanics/Latinos. Journal of the American Society of Nephrology : Jasn. PMID 27650483 DOI: 10.1681/Asn.2016030357  0.417
2016 Mahajan A, Rodan AR, Le TH, Gaulton KJ, Haessler J, Stilp AM, Kamatani Y, Zhu G, Sofer T, Puri S, Schellinger JN, Chu PL, Cechova S, van Zuydam N, ... ... Thornton TA, et al. Trans-ethnic Fine Mapping Highlights Kidney-Function Genes Linked to Salt Sensitivity. American Journal of Human Genetics. 99: 636-646. PMID 27588450 DOI: 10.1016/J.Ajhg.2016.07.012  0.413
2016 McHugh C, Brown L, Thornton TA. Detecting Heterogeneity in Population Structure Across the Genome in Admixed Populations. Genetics. PMID 27440868 DOI: 10.1534/Genetics.115.184184  0.445
2016 Nelson SC, Stilp AM, Papanicolaou GJ, Taylor KD, Rotter JI, Thornton TA, Laurie CC. Improved Imputation Accuracy in Hispanic/Latino Populations with Larger and More Diverse Reference Panels: Applications in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Human Molecular Genetics. PMID 27346520 DOI: 10.1093/Hmg/Ddw174  0.428
2016 Mez J, Mukherjee S, Thornton T, Fardo DW, Trittschuh E, Sutti S, Sherva R, Kauwe JS, Naj AC, Beecham GW, Gross A, Saykin AJ, Green RC, Crane PK, et al. The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable. Neurobiology of Aging. 41: 115-21. PMID 27103524 DOI: 10.1016/J.Neurobiolaging.2016.02.015  0.303
2016 Chen H, Wang C, Conomos MP, Stilp AM, Li Z, Sofer T, Szpiro AA, Chen W, Brehm JM, Celedón JC, Redline S, Papanicolaou GJ, Thornton TA, Laurie CC, Rice K, et al. Control for Population Structure and Relatedness for Binary Traits in Genetic Association Studies via Logistic Mixed Models. American Journal of Human Genetics. PMID 27018471 DOI: 10.1016/J.Ajhg.2016.02.012  0.481
2016 Cade BE, Chen H, Stilp AM, Gleason KJ, Sofer T, Ancoli-Israel S, Arens R, Bell GI, Below JE, Bjonnes AC, Chun S, Conomos MP, Evans DS, Johnson WC, Frazier-Wood AC, ... ... Thornton TA, et al. Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans. American Journal of Respiratory and Critical Care Medicine. PMID 26977737 DOI: 10.1164/Rccm.201512-2431Oc  0.347
2016 Schick UM, Jain D, Hodonsky CJ, Morrison JV, Davis JP, Brown L, Sofer T, Conomos MP, Schurmann C, McHugh CP, Nelson SC, Vadlamudi S, Stilp A, Plantinga A, Baier L, ... ... Thornton TA, et al. Genome-wide Association Study of Platelet Count Identifies Ancestry-Specific Loci in Hispanic/Latino Americans. American Journal of Human Genetics. PMID 26805783 DOI: 10.1016/J.Ajhg.2015.12.003  0.457
2016 Conomos MP, Laurie CA, Stilp AM, Gogarten SM, McHugh CP, Nelson SC, Sofer T, Fernández-Rhodes L, Justice AE, Graff M, Young KL, Seyerle AA, Avery CL, Taylor KD, Rotter JI, ... ... Thornton TA, et al. Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos. American Journal of Human Genetics. 98: 165-184. PMID 26748518 DOI: 10.1016/J.Ajhg.2015.12.001  0.446
2016 Conomos MP, Reiner AP, Weir BS, Thornton TA. Model-free Estimation of Recent Genetic Relatedness. American Journal of Human Genetics. 98: 127-148. PMID 26748516 DOI: 10.1016/J.Ajhg.2015.11.022  0.473
2015 Morrison J, Laurie CC, Marazita ML, Sanders AE, Offenbacher S, Salazar CR, Conomos MP, Thornton T, Jain D, Laurie CA, Kerr K, Papanicolaou G, Taylor K, Kaste LM, Beck JD, et al. Genome-wide association study of dental caries in the Hispanic Communities Health Study/Study of Latinos (HCHS/SOL). Human Molecular Genetics. PMID 26662797 DOI: 10.1093/Hmg/Ddv506  0.46
2015 Auer PL, Nalls M, Meschia JF, Worrall BB, Longstreth WT, Seshadri S, Kooperberg C, Burger KM, Carlson CS, Carty CL, Chen WM, Cupples LA, DeStefano AL, Fornage M, Hardy J, ... ... Thornton TA, et al. Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project. Jama Neurology. 72: 781-8. PMID 25961151 DOI: 10.1001/Jamaneurol.2015.0582  0.331
2015 Conomos MP, Miller MB, Thornton TA. Robust inference of population structure for ancestry prediction and correction of stratification in the presence of relatedness. Genetic Epidemiology. 39: 276-93. PMID 25810074 DOI: 10.1002/Gepi.21896  0.453
2015 Hong X, Hao K, Ladd-Acosta C, Hansen KD, Tsai HJ, Liu X, Xu X, Thornton TA, Caruso D, Keet CA, Sun Y, Wang G, Luo W, Kumar R, Fuleihan R, et al. Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children. Nature Communications. 6: 6304. PMID 25710614 DOI: 10.1038/Ncomms7304  0.426
2015 Thornton TA. Statistical methods for genome-wide and sequencing association studies of complex traits in related samples. Current Protocols in Human Genetics / Editorial Board, Jonathan L. Haines ... [Et Al.]. 84: 1.28.1-9. PMID 25599666 DOI: 10.1002/0471142905.Hg0128S84  0.475
2014 Blue EM, Cheung CY, Glazner CG, Conomos MP, Lewis SM, Sverdlov S, Thornton T, Wijsman EM. Identity-by-descent graphs offer a flexible framework for imputation and both linkage and association analyses. Bmc Proceedings. 8: S19. PMID 25519371 DOI: 10.1186/1753-6561-8-S1-S19  0.396
2014 Thornton T, Conomos MP, Sverdlov S, Blue EM, Cheung CY, Glazner CG, Lewis SM, Wijsman EM. Estimating and adjusting for ancestry admixture in statistical methods for relatedness inference, heritability estimation, and association testing. Bmc Proceedings. 8: S5. PMID 25519330 DOI: 10.1186/1753-6561-8-S1-S5  0.435
2014 Thornton TA, Bermejo JL. Local and global ancestry inference and applications to genetic association analysis for admixed populations. Genetic Epidemiology. 38: S5-S12. PMID 25112189 DOI: 10.1002/Gepi.21819  0.513
2014 Hoffmann TJ, Tang H, Thornton TA, Caan B, Haan M, Millen AE, Thomas F, Risch N. Genome-wide association and admixture analysis of glaucoma in the Women's Health Initiative. Human Molecular Genetics. 23: 6634-43. PMID 25027321 DOI: 10.1093/Hmg/Ddu364  0.402
2014 Alam MT, Petit RA, Crispell EK, Thornton TA, Conneely KN, Jiang Y, Satola SW, Read TD. Dissecting vancomycin-intermediate resistance in staphylococcus aureus using genome-wide association. Genome Biology and Evolution. 6: 1174-85. PMID 24787619 DOI: 10.1093/Gbe/Evu092  0.396
2013 Fohner A, Muzquiz LI, Austin MA, Gaedigk A, Gordon A, Thornton T, Rieder MJ, Pershouse MA, Putnam EA, Howlett K, Beatty P, Thummel KE, Woodahl EL. Pharmacogenetics in American Indian populations: analysis of CYP2D6, CYP3A4, CYP3A5, and CYP2C9 in the Confederated Salish and Kootenai Tribes. Pharmacogenetics and Genomics. 23: 403-14. PMID 23778323 DOI: 10.1097/Fpc.0B013E3283629Ce9  0.318
2013 Coram MA, Duan Q, Hoffmann TJ, Thornton T, Knowles JW, Johnson NA, Ochs-Balcom HM, Donlon TA, Martin LW, Eaton CB, Robinson JG, Risch NJ, Zhu X, Kooperberg C, Li Y, et al. Genome-wide characterization of shared and distinct genetic components that influence blood lipid levels in ethnically diverse human populations. American Journal of Human Genetics. 92: 904-16. PMID 23726366 DOI: 10.1016/J.Ajhg.2013.04.025  0.474
2013 Kaklamani VG, Hoffmann TJ, Thornton TA, Hayes G, Chlebowski R, Van Horn L, Mantzoros C. Adiponectin pathway polymorphisms and risk of breast cancer in African Americans and Hispanics in the Women's Health Initiative. Breast Cancer Research and Treatment. 139: 461-8. PMID 23624817 DOI: 10.1007/S10549-013-2546-6  0.331
2013 Ochs-Balcom HM, Preus L, Wactawski-Wende J, Nie J, Johnson NA, Zakharia F, Tang H, Carlson C, Carty C, Chen Z, Hoffman T, Hutter CM, Jackson RD, Kaplan RC, Li L, ... ... Thornton TA, et al. Association of DXA-derived bone mineral density and fat mass with African ancestry. The Journal of Clinical Endocrinology and Metabolism. 98: E713-7. PMID 23436924 DOI: 10.1210/Jc.2012-3921  0.301
2013 Thornton TA, Austin MA. Software and data resources for genetic association studies: Mini review Cab Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources. 8. DOI: 10.1079/Pavsnnr20138057  0.424
2013 Trittschuh E, Mukherjee S, Thornton T, Fardo D, Waterston L, Crane P, Mez J, Sherva R, Kauwe J, Naj A, Beecham G, Gross A, Saykin A, Green R. P3-003: Genome-wide SNP analysis finds executive-prominent late-onset Alzheimer's disease is highly heritable Alzheimer's & Dementia. 9: P550-P551. DOI: 10.1016/J.Jalz.2013.05.1072  0.397
2013 Mukherjee S, Thornton T, Naj A, Kim S, Kauwe J, Fardo D, Valladares O, Wijsman E, Schellenberg G, Crane P. GWAS of the joint ADGC data set identifies novel common variants associated with late-onset Alzheimer's disease Alzheimers & Dementia. 9: 550. DOI: 10.1016/J.Jalz.2013.05.1071  0.369
2012 Thornton T, Tang H, Hoffmann TJ, Ochs-Balcom HM, Caan BJ, Risch N. Estimating kinship in admixed populations. American Journal of Human Genetics. 91: 122-38. PMID 22748210 DOI: 10.1016/J.Ajhg.2012.05.024  0.456
2012 Thornton T, Zhang Q, Cai X, Ober C, McPeek MS. XM: association testing on the X-chromosome in case-control samples with related individuals. Genetic Epidemiology. 36: 438-50. PMID 22552845 DOI: 10.1002/Gepi.21638  0.678
2011 Tore S, Casula S, Casu G, Concas MP, Pistidda P, Persico I, Sassu A, Maestrale GB, Mele C, Caruso MR, Bonerba B, Usai P, Deiana I, Thornton T, Pirastu M, et al. Application of a new method for GWAS in a related case/control sample with known pedigree structure: identification of new loci for nephrolithiasis. Plos Genetics. 7: e1001281. PMID 21283782 DOI: 10.1371/Journal.Pgen.1001281  0.509
2010 Phasukkijwatana N, Kunhapan B, Stankovich J, Chuenkongkaew WL, Thomson R, Thornton T, Bahlo M, Mushiroda T, Nakamura Y, Mahasirimongkol S, Tun AW, Srisawat C, Limwongse C, Peerapittayamongkol C, Sura T, et al. Genome-wide linkage scan and association study of PARL to the expression of LHON families in Thailand. Human Genetics. 128: 39-49. PMID 20407791 DOI: 10.1007/S00439-010-0821-8  0.382
2010 Thornton T, McPeek MS. ROADTRIPS: case-control association testing with partially or completely unknown population and pedigree structure. American Journal of Human Genetics. 86: 172-84. PMID 20137780 DOI: 10.1016/J.Ajhg.2010.01.001  0.707
2009 FitzGerald LM, Patterson B, Thomson R, Polanowski A, Quinn S, Brohede J, Thornton T, Challis D, Mackey DA, Dwyer T, Foote S, Hannan GN, Stankovich J, McKay JD, Dickinson JL. Identification of a prostate cancer susceptibility gene on chromosome 5p13q12 associated with risk of both familial and sporadic disease. European Journal of Human Genetics : Ejhg. 17: 368-77. PMID 18830231 DOI: 10.1038/Ejhg.2008.171  0.398
2007 Thornton T, McPeek MS. Case-control association testing with related individuals: a more powerful quasi-likelihood score test. American Journal of Human Genetics. 81: 321-37. PMID 17668381 DOI: 10.1086/519497  0.685
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