Year |
Citation |
Score |
2016 |
Qvit N, Schechtman D, Pena DA, Berti DA, Soares CO, Miao Q, Liang LA, Baron LA, Teh-Poot C, Martínez-Vega P, Ramirez-Sierra MJ, Churchill E, Cunningham AD, Malkovskiy AV, Federspiel NA, et al. Scaffold proteins LACK and TRACK as potential drug targets in kinetoplastid parasites: Development of inhibitors. International Journal For Parasitology. Drugs and Drug Resistance. 6: 74-84. PMID 27054066 DOI: 10.1016/J.Ijpddr.2016.02.003 |
0.344 |
|
2011 |
Ferreira JC, Koyanagi T, Palaniyandi SS, Fajardo G, Churchill EN, Budas G, Disatnik MH, Bernstein D, Brum PC, Mochly-Rosen D. Pharmacological inhibition of βIIPKC is cardioprotective in late-stage hypertrophy. Journal of Molecular and Cellular Cardiology. 51: 980-7. PMID 21920368 DOI: 10.1016/J.Yjmcc.2011.08.025 |
0.426 |
|
2010 |
Budas GR, Churchill EN, Disatnik MH, Sun L, Mochly-Rosen D. Mitochondrial import of PKCepsilon is mediated by HSP90: a role in cardioprotection from ischaemia and reperfusion injury. Cardiovascular Research. 88: 83-92. PMID 20558438 DOI: 10.1093/Cvr/Cvq154 |
0.522 |
|
2010 |
Churchill EN, Ferreira JC, Brum PC, Szweda LI, Mochly-Rosen D. Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. Cardiovascular Research. 85: 385-94. PMID 19820255 DOI: 10.1093/Cvr/Cvp334 |
0.652 |
|
2010 |
Budas GR, Churchill EN, Disatnik MH, Sun L, Mochly-rosen D. Mitochondrial import of PKCε is mediated by HSP90: A role in cardioprotection from ischaemia and reperfusion injury Continuing Education in Anaesthesia, Critical Care and Pain. 88: 83-92. |
0.455 |
|
2009 |
Churchill EN, Qvit N, Mochly-Rosen D. Rationally designed peptide regulators of protein kinase C. Trends in Endocrinology and Metabolism: Tem. 20: 25-33. PMID 19056296 DOI: 10.1016/J.Tem.2008.10.002 |
0.418 |
|
2009 |
Churchill EN, Disatnik MH, Mochly-Rosen D. Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2. Journal of Molecular and Cellular Cardiology. 46: 278-84. PMID 18983847 DOI: 10.1016/J.Yjmcc.2008.09.713 |
0.522 |
|
2008 |
Churchill EN, Disatnik MH, Budas GR, Mochly-Rosen D. Ethanol for cardiac ischemia: the role of protein kinase c. Therapeutic Advances in Cardiovascular Disease. 2: 469-83. PMID 19124442 DOI: 10.1177/1753944708094735 |
0.328 |
|
2008 |
Chen CH, Budas GR, Churchill EN, Disatnik MH, Hurley TD, Mochly-Rosen D. Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart. Science (New York, N.Y.). 321: 1493-5. PMID 18787169 DOI: 10.1126/Science.1158554 |
0.519 |
|
2008 |
Churchill E, Budas G, Vallentin A, Koyanagi T, Mochly-Rosen D. PKC isozymes in chronic cardiac disease: possible therapeutic targets? Annual Review of Pharmacology and Toxicology. 48: 569-99. PMID 17919087 DOI: 10.1146/Annurev.Pharmtox.48.121806.154902 |
0.424 |
|
2007 |
Churchill EN, Mochly-Rosen D. The roles of PKCδ and ε isoenzymes in the regulation of myocardial ischaemia/reperfusion injury Biochemical Society Transactions. 35: 1040-1042. PMID 17956273 DOI: 10.1042/Bst0351040 |
0.576 |
|
2007 |
Budas GR, Koyanagi T, Churchill EN, Mochly-Rosen D. Competitive inhibitors and allosteric activators of protein kinase C isoenzymes: A personal account and progress report on transferring academic discoveries to the clinic Biochemical Society Transactions. 35: 1021-1026. PMID 17956268 DOI: 10.1042/Bst0351021 |
0.388 |
|
2007 |
Qi X, Vallentin A, Churchill E, Mochly-Rosen D. deltaPKC participates in the endoplasmic reticulum stress-induced response in cultured cardiac myocytes and ischemic heart. Journal of Molecular and Cellular Cardiology. 43: 420-8. PMID 17825316 DOI: 10.1016/J.Yjmcc.2007.07.061 |
0.44 |
|
2007 |
Budas GR, Churchill EN, Mochly-Rosen D. Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury. Pharmacological Research. 55: 523-36. PMID 17576073 DOI: 10.1016/J.Phrs.2007.04.005 |
0.533 |
|
2007 |
Brandman R, Disatnik MH, Churchill E, Mochly-Rosen D. Peptides derived from the C2 domain of protein kinase C epsilon (epsilon PKC) modulate epsilon PKC activity and identify potential protein-protein interaction surfaces. The Journal of Biological Chemistry. 282: 4113-23. PMID 17142835 DOI: 10.1074/Jbc.M608521200 |
0.408 |
|
2006 |
Inagaki K, Churchill E, Mochly-Rosen D. Epsilon protein kinase C as a potential therapeutic target for the ischemic heart. Cardiovascular Research. 70: 222-30. PMID 16635641 DOI: 10.1016/J.Cardiores.2006.02.015 |
0.52 |
|
2006 |
Churchill EN, Mochly-Rosen D. A81. Ischemic preconditioining decreases delta PKC levels resulting in diminished translocation during reperfusion Journal of Molecular and Cellular Cardiology. 40: 868. DOI: 10.1016/J.Yjmcc.2006.03.297 |
0.355 |
|
2005 |
Churchill EN, Szweda LI. Translocation of deltaPKC to mitochondria during cardiac reperfusion enhances superoxide anion production and induces loss in mitochondrial function. Archives of Biochemistry and Biophysics. 439: 194-9. PMID 15963450 DOI: 10.1016/J.Abb.2005.05.007 |
0.64 |
|
2005 |
Churchill EN, Murriel CL, Chen CH, Mochly-Rosen D, Szweda LI. Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation. Circulation Research. 97: 78-85. PMID 15961716 DOI: 10.1161/01.Res.0000173896.32522.6E |
0.666 |
|
2004 |
Murriel CL, Churchill E, Inagaki K, Szweda LI, Mochly-Rosen D. Protein kinase Cdelta activation induces apoptosis in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria. The Journal of Biological Chemistry. 279: 47985-91. PMID 15339931 DOI: 10.1074/Jbc.M405071200 |
0.661 |
|
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