Abigail R. Lambert, Ph.D. - Publications

Affiliations: 
2009 University of Washington, Seattle, Seattle, WA 
Area:
Biochemistry

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Luyten YA, Hausman DE, Young JC, Doyle LA, Higashi KM, Ubilla-Rodriguez NC, Lambert AR, Arroyo CS, Forsberg KJ, Morgan RD, Stoddard BL, Kaiser BK. Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Research. PMID 35511079 DOI: 10.1093/nar/gkac311  0.593
2020 Lambert AR, Hallinan JP, Werther R, Głów D, Stoddard BL. Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition. Structure (London, England : 1993). PMID 32359399 DOI: 10.1016/J.Str.2020.04.009  0.671
2017 Niyonzima N, Lambert AR, Werther R, De Silva Feelixge H, Roychoudhury P, Greninger AL, Stone D, Stoddard BL, Jerome KR. Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses. Protein Engineering, Design & Selection : Peds. 30: 503-522. PMID 28873986 DOI: 10.1093/Protein/Gzx037  0.683
2017 Moffett HF, Coon ME, Radtke S, Stephan SB, McKnight L, Lambert A, Stoddard BL, Kiem HP, Stephan MT. Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers. Nature Communications. 8: 389. PMID 28855514 DOI: 10.1038/S41467-017-00505-8  0.484
2017 Werther R, Hallinan JP, Lambert AR, Havens K, Pogson M, Jarjour J, Galizi R, Windbichler N, Crisanti A, Nolan T, Stoddard BL. Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity. Nucleic Acids Research. PMID 28637173 DOI: 10.1093/Nar/Gkx544  0.691
2017 Jacoby K, Lambert AR, Scharenberg AM. Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX). Nucleic Acids Research. 45: e11. PMID 28180328 DOI: 10.1093/Nar/Gkw864  0.51
2016 Jacoby K, Lambert AR, Scharenberg AM. Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX). Nucleic Acids Research. PMID 27683221 DOI: 10.1093/nar/gkw864  0.43
2016 Lambert AR, Hallinan JP, Shen BW, Chik JK, Bolduc JM, Kulshina N, Robins LI, Kaiser BK, Jarjour J, Havens K, Scharenberg AM, Stoddard BL. Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure (London, England : 1993). PMID 27133026 DOI: 10.1016/J.Str.2016.03.024  0.697
2015 Shen BW, Lambert A, Walker BC, Stoddard BL, Kaiser BK. The structural basis of asymmetry in DNA binding and cleavage as exhibited by the I-SmaMI LAGLIDADG meganuclease. Journal of Molecular Biology. PMID 26705195 DOI: 10.1016/J.Jmb.2015.12.005  0.706
2015 Shen BW, Walker B, Lambert A, Stoddard BL, Kaiser BK. The structural basis of asymmetry in DNA recognition and catalysis: binding and cleavage by the I-SmaMI meganuclease Acta Crystallographica Section a Foundations and Advances. 71: s251-s251. DOI: 10.1107/S2053273315096163  0.65
2014 Baxter SK, Scharenberg AM, Lambert AR. Engineering and flow-cytometric analysis of chimeric LAGLIDADG homing endonucleases from homologous I-OnuI-family enzymes. Methods in Molecular Biology (Clifton, N.J.). 1123: 191-221. PMID 24510269 DOI: 10.1007/978-1-62703-968-0_14  0.527
2013 Baxter SK, Lambert AR, Scharenberg AM, Jarjour J. Flow cytometric assays for interrogating LAGLIDADG homing endonuclease DNA-binding and cleavage properties. Methods in Molecular Biology (Clifton, N.J.). 978: 45-61. PMID 23423888 DOI: 10.1007/978-1-62703-293-3_4  0.553
2012 Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, et al. Coupling endonucleases with DNA end-processing enzymes to drive gene disruption. Nature Methods. 9: 973-5. PMID 22941364 DOI: 10.1038/Nmeth.2177  0.517
2012 Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL, Scharenberg AM. Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases. Nucleic Acids Research. 40: 7985-8000. PMID 22684507 DOI: 10.1093/Nar/Gks502  0.58
2012 Taylor GK, Petrucci LH, Lambert AR, Baxter SK, Jarjour J, Stoddard BL. LAHEDES: the LAGLIDADG homing endonuclease database and engineering server. Nucleic Acids Research. 40: W110-6. PMID 22570419 DOI: 10.1093/Nar/Gks365  0.68
2011 Takeuchi R, Lambert AR, Mak AN, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL. Tapping natural reservoirs of homing endonucleases for targeted gene modification. Proceedings of the National Academy of Sciences of the United States of America. 108: 13077-82. PMID 21784983 DOI: 10.1073/Pnas.1107719108  0.673
2011 Siegel JB, Zanghellini A, Lovick HM, Kiss G, Lambert AR, Clair JLS, Gallaher JL, Hilvert D, Gelb MH, Stoddard BL, Houk KN, Michael FE, Baker D. A Biocatalytic Diels-Alder Reaction Using a DesignedEnzyme Synfacts. 2011: 323-323. DOI: 10.1055/S-0030-1259455  0.46
2010 Mak AN, Lambert AR, Stoddard BL. Folding, DNA recognition, and function of GIY-YIG endonucleases: crystal structures of R.Eco29kI. Structure (London, England : 1993). 18: 1321-31. PMID 20800503 DOI: 10.1016/J.Str.2010.07.006  0.681
2010 Siegel JB, Zanghellini A, Lovick HM, Kiss G, Lambert AR, St Clair JL, Gallaher JL, Hilvert D, Gelb MH, Stoddard BL, Houk KN, Michael FE, Baker D. Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction. Science (New York, N.Y.). 329: 309-13. PMID 20647463 DOI: 10.1126/Science.1190239  0.534
2008 Lambert AR, Sussman D, Shen B, Maunus R, Nix J, Samuelson J, Xu SY, Stoddard BL. Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding. Structure (London, England : 1993). 16: 558-69. PMID 18400177 DOI: 10.1016/J.Str.2008.01.017  0.667
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