Year |
Citation |
Score |
2022 |
Luyten YA, Hausman DE, Young JC, Doyle LA, Higashi KM, Ubilla-Rodriguez NC, Lambert AR, Arroyo CS, Forsberg KJ, Morgan RD, Stoddard BL, Kaiser BK. Identification and characterization of the WYL BrxR protein and its gene as separable regulatory elements of a BREX phage restriction system. Nucleic Acids Research. PMID 35511079 DOI: 10.1093/nar/gkac311 |
0.593 |
|
2020 |
Lambert AR, Hallinan JP, Werther R, Głów D, Stoddard BL. Optimization of Protein Thermostability and Exploitation of Recognition Behavior to Engineer Altered Protein-DNA Recognition. Structure (London, England : 1993). PMID 32359399 DOI: 10.1016/J.Str.2020.04.009 |
0.671 |
|
2017 |
Niyonzima N, Lambert AR, Werther R, De Silva Feelixge H, Roychoudhury P, Greninger AL, Stone D, Stoddard BL, Jerome KR. Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses. Protein Engineering, Design & Selection : Peds. 30: 503-522. PMID 28873986 DOI: 10.1093/Protein/Gzx037 |
0.683 |
|
2017 |
Moffett HF, Coon ME, Radtke S, Stephan SB, McKnight L, Lambert A, Stoddard BL, Kiem HP, Stephan MT. Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers. Nature Communications. 8: 389. PMID 28855514 DOI: 10.1038/S41467-017-00505-8 |
0.484 |
|
2017 |
Werther R, Hallinan JP, Lambert AR, Havens K, Pogson M, Jarjour J, Galizi R, Windbichler N, Crisanti A, Nolan T, Stoddard BL. Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity. Nucleic Acids Research. PMID 28637173 DOI: 10.1093/Nar/Gkx544 |
0.691 |
|
2017 |
Jacoby K, Lambert AR, Scharenberg AM. Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX). Nucleic Acids Research. 45: e11. PMID 28180328 DOI: 10.1093/Nar/Gkw864 |
0.51 |
|
2016 |
Jacoby K, Lambert AR, Scharenberg AM. Characterization of homing endonuclease binding and cleavage specificities using yeast surface display SELEX (YSD-SELEX). Nucleic Acids Research. PMID 27683221 DOI: 10.1093/nar/gkw864 |
0.43 |
|
2016 |
Lambert AR, Hallinan JP, Shen BW, Chik JK, Bolduc JM, Kulshina N, Robins LI, Kaiser BK, Jarjour J, Havens K, Scharenberg AM, Stoddard BL. Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity. Structure (London, England : 1993). PMID 27133026 DOI: 10.1016/J.Str.2016.03.024 |
0.697 |
|
2015 |
Shen BW, Lambert A, Walker BC, Stoddard BL, Kaiser BK. The structural basis of asymmetry in DNA binding and cleavage as exhibited by the I-SmaMI LAGLIDADG meganuclease. Journal of Molecular Biology. PMID 26705195 DOI: 10.1016/J.Jmb.2015.12.005 |
0.706 |
|
2015 |
Shen BW, Walker B, Lambert A, Stoddard BL, Kaiser BK. The structural basis of asymmetry in DNA recognition and catalysis: binding and cleavage by the I-SmaMI meganuclease Acta Crystallographica Section a Foundations and Advances. 71: s251-s251. DOI: 10.1107/S2053273315096163 |
0.65 |
|
2014 |
Baxter SK, Scharenberg AM, Lambert AR. Engineering and flow-cytometric analysis of chimeric LAGLIDADG homing endonucleases from homologous I-OnuI-family enzymes. Methods in Molecular Biology (Clifton, N.J.). 1123: 191-221. PMID 24510269 DOI: 10.1007/978-1-62703-968-0_14 |
0.527 |
|
2013 |
Baxter SK, Lambert AR, Scharenberg AM, Jarjour J. Flow cytometric assays for interrogating LAGLIDADG homing endonuclease DNA-binding and cleavage properties. Methods in Molecular Biology (Clifton, N.J.). 978: 45-61. PMID 23423888 DOI: 10.1007/978-1-62703-293-3_4 |
0.553 |
|
2012 |
Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K, Ryu BY, Kiem HP, Gouble A, Paques F, Rawlings DJ, et al. Coupling endonucleases with DNA end-processing enzymes to drive gene disruption. Nature Methods. 9: 973-5. PMID 22941364 DOI: 10.1038/Nmeth.2177 |
0.517 |
|
2012 |
Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL, Scharenberg AM. Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases. Nucleic Acids Research. 40: 7985-8000. PMID 22684507 DOI: 10.1093/Nar/Gks502 |
0.58 |
|
2012 |
Taylor GK, Petrucci LH, Lambert AR, Baxter SK, Jarjour J, Stoddard BL. LAHEDES: the LAGLIDADG homing endonuclease database and engineering server. Nucleic Acids Research. 40: W110-6. PMID 22570419 DOI: 10.1093/Nar/Gks365 |
0.68 |
|
2011 |
Takeuchi R, Lambert AR, Mak AN, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL. Tapping natural reservoirs of homing endonucleases for targeted gene modification. Proceedings of the National Academy of Sciences of the United States of America. 108: 13077-82. PMID 21784983 DOI: 10.1073/Pnas.1107719108 |
0.673 |
|
2011 |
Siegel JB, Zanghellini A, Lovick HM, Kiss G, Lambert AR, Clair JLS, Gallaher JL, Hilvert D, Gelb MH, Stoddard BL, Houk KN, Michael FE, Baker D. A Biocatalytic Diels-Alder Reaction Using a DesignedEnzyme Synfacts. 2011: 323-323. DOI: 10.1055/S-0030-1259455 |
0.46 |
|
2010 |
Mak AN, Lambert AR, Stoddard BL. Folding, DNA recognition, and function of GIY-YIG endonucleases: crystal structures of R.Eco29kI. Structure (London, England : 1993). 18: 1321-31. PMID 20800503 DOI: 10.1016/J.Str.2010.07.006 |
0.681 |
|
2010 |
Siegel JB, Zanghellini A, Lovick HM, Kiss G, Lambert AR, St Clair JL, Gallaher JL, Hilvert D, Gelb MH, Stoddard BL, Houk KN, Michael FE, Baker D. Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction. Science (New York, N.Y.). 329: 309-13. PMID 20647463 DOI: 10.1126/Science.1190239 |
0.534 |
|
2008 |
Lambert AR, Sussman D, Shen B, Maunus R, Nix J, Samuelson J, Xu SY, Stoddard BL. Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding. Structure (London, England : 1993). 16: 558-69. PMID 18400177 DOI: 10.1016/J.Str.2008.01.017 |
0.667 |
|
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