Nikolaos P. Daskalakis, M.D. Ph.D. - Publications

Affiliations: 
2017- McLean Hospital / Harvard Medical School, Belmont, MA, United States 
Area:
Stress, PTSD, Schizophrenia
Website:
https://www.linkedin.com/profile/preview?vpa=pub&locale=en_US

91 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Daskalakis NP, Iatrou A, Chatzinakos C, Jajoo A, Snijders C, Wylie D, DiPietro CP, Tsatsani I, Chen CY, Pernia CD, Soliva-Estruch M, Arasappan D, Bharadwaj RA, Collado-Torres L, Wuchty S, et al. Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood. Science (New York, N.Y.). 384: eadh3707. PMID 38781393 DOI: 10.1126/science.adh3707  0.812
2024 Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, et al. Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. Nature Genetics. PMID 38637617 DOI: 10.1038/s41588-024-01707-9  0.815
2024 Granger SJ, May V, Hammack SE, Akman E, Jobson SA, Olson EA, Pernia CD, Daskalakis NP, Ravichandran C, Carlezon WA, Ressler KJ, Rauch SL, Rosso IM. Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder. European Journal of Psychotraumatology. 15: 2335793. PMID 38590134 DOI: 10.1080/20008066.2024.2335793  0.599
2024 Clifford RE, Maihofer AX, Chatzinakos C, Coleman JRI, Daskalakis NP, Gasperi M, Hogan K, Mikita EA, Stein MB, Tcheandjieu C, Telese F, Zuo Y, Ryan AF, Nievergelt CM. Genetic architecture distinguishes tinnitus from hearing loss. Nature Communications. 15: 614. PMID 38242899 DOI: 10.1038/s41467-024-44842-x  0.724
2023 Granger SJ, May V, Hammack SE, Akman E, Jobson SA, Olson EA, Pernia CD, Daskalakis NP, Ravichandran C, Carlezon WA, Ressler KJ, Rauch SL, Rosso IM. Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder. Medrxiv : the Preprint Server For Health Sciences. PMID 37693514 DOI: 10.1101/2023.08.31.23294894  0.612
2023 Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JR, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, et al. Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. Medrxiv : the Preprint Server For Health Sciences. PMID 37693460 DOI: 10.1101/2023.08.31.23294915  0.809
2023 Chatzinakos C, Pernia CD, Morrison FG, Iatrou A, McCullough KM, Schuler H, Snijders C, Bajaj T, DiPietro CP, Soliva Estruch M, Gassen NC, Anastasopoulos C, Bharadwaj RA, Bowlby BC, Hartmann J, ... ... Daskalakis NP, et al. Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response. The American Journal of Psychiatry. appiajp20220478. PMID 37491937 DOI: 10.1176/appi.ajp.20220478  0.788
2023 Clancy KJ, Devignes Q, Kumar P, May V, Hammack SE, Akman E, Casteen EJ, Pernia CD, Jobson SA, Lewis MW, Daskalakis NP, Carlezon WA, Ressler KJ, Rauch SL, Rosso IM. Circulating PACAP levels are associated with increased amygdala-default mode network resting-state connectivity in posttraumatic stress disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37161077 DOI: 10.1038/s41386-023-01593-5  0.594
2023 Bassil K, Krontira AC, Leroy T, Escoto AIH, Snijders C, Pernia CD, Pasterkamp RJ, de Nijs L, van den Hove D, Kenis G, Boks MP, Vadodaria K, Daskalakis NP, Binder EB, Rutten BPF. modeling of the neurobiological effects of glucocorticoids: A review. Neurobiology of Stress. 23: 100530. PMID 36891528 DOI: 10.1016/j.ynstr.2023.100530  0.523
2022 Bountress KE, Bustamante D, Subbie-Saenz de Viteri S, Chatzinakos C, Sheerin C, Daskalakis NP, Edenberg HJ, Peterson RE, Webb BT, Meyers J, Amstadter A. Differences in genetic correlations between posttraumatic stress disorder and alcohol-related problems phenotypes compared to alcohol consumption-related phenotypes. Psychological Medicine. 1-11. PMID 36177877 DOI: 10.1017/S0033291722002999  0.714
2022 Daskalakis NP, Meijer OC, de Kloet ER. Mineralocorticoid receptor and glucocorticoid receptor work alone and together in cell-type-specific manner: Implications for resilience prediction and targeted therapy. Neurobiology of Stress. 18: 100455. PMID 35601687 DOI: 10.1016/j.ynstr.2022.100455  0.653
2022 Marchese S, Cancelmo L, Diab O, Cahn L, Aaronson C, Daskalakis NP, Schaffer J, Horn SR, Johnson JS, Schechter C, Desarnaud F, Bierer LM, Makotkine I, Flory JD, Crane M, et al. Altered gene expression and PTSD symptom dimensions in World Trade Center responders. Molecular Psychiatry. PMID 35177824 DOI: 10.1038/s41380-022-01457-2  0.521
2021 Maihofer AX, Choi KW, Coleman JRI, Daskalakis NP, Denckla CA, Ketema E, Morey RA, Polimanti R, Ratanatharathorn A, Torres K, Wingo AP, Zai CC, Aiello AE, Almli LM, Amstadter AB, et al. Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. Biological Psychiatry. PMID 34865855 DOI: 10.1016/j.biopsych.2021.09.020  0.709
2021 Dalvie S, Chatzinakos C, Al Zoubi O, Georgiadis F, Lancashire L, Daskalakis NP. From genetics to systems biology of stress-related mental disorders. Neurobiology of Stress. 15: 100393. PMID 34584908 DOI: 10.1016/j.ynstr.2021.100393  0.766
2021 Lori A, Schultebraucks K, Galatzer-Levy I, Daskalakis NP, Katrinli S, Smith AK, Myers AJ, Richholt R, Huentelman M, Guffanti G, Wuchty S, Gould F, Harvey PD, Nemeroff CB, Jovanovic T, et al. Transcriptome-wide association study of post-trauma symptom trajectories identified GRIN3B as a potential biomarker for PTSD development. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34188182 DOI: 10.1038/s41386-021-01073-8  0.596
2021 Hartmann J, Bajaj T, Klengel C, Chatzinakos C, Ebert T, Dedic N, McCullough KM, Lardenoije R, Joëls M, Meijer OC, McCann KE, Dudek SM, Sarabdjitsingh RA, Daskalakis NP, Klengel T, et al. Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5. Cell Reports. 35: 109185. PMID 34077736 DOI: 10.1016/j.celrep.2021.109185  0.781
2021 Ferland-Beckham C, Chaby LE, Daskalakis NP, Knox D, Liberzon I, Lim MM, McIntyre C, Perrine SA, Risbrough VB, Sabban EL, Jeromin A, Haas M. Systematic Review and Methodological Considerations for the Use of Single Prolonged Stress and Fear Extinction Retention in Rodents. Frontiers in Behavioral Neuroscience. 15: 652636. PMID 34054443 DOI: 10.3389/fnbeh.2021.652636  0.303
2021 Chatzinakos C, Lee D, Cai N, Vladimirov VI, Webb BT, Riley BP, Flint J, Kendler KS, Ressler KJ, Daskalakis NP, Bacanu SA. Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 33576176 DOI: 10.1002/ajmg.b.32834  0.784
2020 Daskalakis NP, Xu C, Bader HN, Chatzinakos C, Weber P, Makotkine I, Lehrner A, Bierer LM, Binder EB, Yehuda R. Intergenerational trauma is associated with expression alterations in glucocorticoid- and immune-related genes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33173192 DOI: 10.1038/s41386-020-00900-8  0.79
2020 McCullough KM, Chatzinakos C, Hartmann J, Missig G, Neve RL, Fenster RJ, Carlezon WA, Daskalakis NP, Ressler KJ. Author Correction: Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning. Nature Communications. 11: 5529. PMID 33110083 DOI: 10.1038/s41467-020-19534-x  0.764
2020 McCullough KM, Chatzinakos C, Hartmann J, Missig G, Neve RL, Fenster RJ, Carlezon WA, Daskalakis NP, Ressler KJ. Genome-wide translational profiling of amygdala Crh-expressing neurons reveals role for CREB in fear extinction learning. Nature Communications. 11: 5180. PMID 33057013 DOI: 10.1038/s41467-020-18985-6  0.783
2020 Chatzinakos C, Georgiadis F, Lee D, Cai N, Vladimirov VI, Docherty A, Webb BT, Riley BP, Flint J, Kendler KS, Daskalakis NP, Bacanu SA. TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 32954640 DOI: 10.1002/Ajmg.B.32823  0.787
2020 Chatzinakos C, Georgiadis F, Daskalakis NP. GWAS meets transcriptomics: from genetic letters to transcriptomic words of neuropsychiatric risk. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32873903 DOI: 10.1038/S41386-020-00835-0  0.712
2020 Huckins LM, Chatzinakos C, Breen MS, Hartmann J, Klengel T, da Silva Almeida AC, Dobbyn A, Girdhar K, Hoffman GE, Klengel C, Logue MW, Lori A, Maihofer AX, Morrison FG, Nguyen HT, ... ... Daskalakis NP, et al. Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts. Cell Reports. 31: 107716. PMID 32492425 DOI: 10.1016/J.Celrep.2020.107716  0.808
2020 Wolf EJ, Logue MW, Zhao X, Daskalakis NP, Morrison FG, Escarfulleri S, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Chen C, Abraham CR, Miller MW. PTSD and the klotho longevity gene: Evaluation of longitudinal effects on inflammation via DNA methylation. Psychoneuroendocrinology. 117: 104656. PMID 32438247 DOI: 10.1016/J.Psyneuen.2020.104656  0.404
2020 Bierer LM, Bader HN, Daskalakis NP, Lehrner A, Provençal N, Wiechmann T, Klengel T, Makotkine I, Binder EB, Yehuda R. Intergenerational Effects of Maternal Holocaust Exposure on Methylation. The American Journal of Psychiatry. appiajp201919060618. PMID 32312110 DOI: 10.1176/Appi.Ajp.2019.19060618  0.599
2020 Logue MW, Miller MW, Wolf EJ, Huber BR, Morrison FG, Zhou Z, Zheng Y, Smith AK, Daskalakis NP, Ratanatharathorn A, Uddin M, Nievergelt CM, Ashley-Koch AE, Baker DG, Beckham JC, et al. An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci. Clinical Epigenetics. 12: 46. PMID 32171335 DOI: 10.1186/S13148-020-0820-0  0.427
2020 Breen MS, Bierer LM, Daskalakis NP, Bader HN, Makotkine I, Chattopadhyay M, Xu C, Grice AB, Tocheva AS, Flory JD, Buxbaum JD, Meaney MJ, Brennand K, Yehuda R. Correction: Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development. Translational Psychiatry. 10: 1. PMID 32066695 DOI: 10.1038/S41398-019-0665-5  0.644
2020 Lasseter H, Provost A, Daskalakis N, Chaby L, Haas M, Jeromin A. Cross-Platform Comparison of Immunoassay Technologies to Assess Cytokine Markers in Patients With Post-Traumatic Stress Disorder and Parkinson’s Disease Biological Psychiatry. 87. DOI: 10.1016/J.Biopsych.2020.02.968  0.358
2020 Morrison F, McCullough K, Chatzinakos C, Miller M, Logue M, Wolf E, Carlezon W, Ressler K, Kellis M, Huber B, Daskalakis N. Single-Nucleus Transcriptomic Analysis of PTSD and MDD in Human Post-Mortem DLPFC Biological Psychiatry. 87: S25. DOI: 10.1016/J.Biopsych.2020.02.088  0.787
2019 Mavrikaki M, Pantano L, Potter D, Rogers-Grazado MA, Anastasiadou E, Slack FJ, Amr SS, Ressler KJ, Daskalakis NP, Chartoff E. Sex-Dependent Changes in miRNA Expression in the Bed Nucleus of the Stria Terminalis Following Stress. Frontiers in Molecular Neuroscience. 12: 236. PMID 31636537 DOI: 10.3389/Fnmol.2019.00236  0.606
2019 Jeromin A, Lasseter HC, Provost AC, Daskalakis NP, Etkin A, Gehrman P, Lancashire L, Marx BP, McGlinchey R, Haas M. Driving Progress in Posttraumatic Stress Disorder Biomarkers. Biological Psychiatry. PMID 31623824 DOI: 10.1016/J.Biopsych.2019.07.036  0.399
2019 Nievergelt CM, Maihofer AX, Klengel T, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Dalvie S, Duncan LE, Gelernter J, Levey DF, Logue MW, Polimanti R, Provost AC, Ratanatharathorn A, ... ... Daskalakis NP, et al. International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nature Communications. 10: 4558. PMID 31594949 DOI: 10.1038/S41467-019-12576-W  0.713
2019 Breen MS, Bierer LM, Daskalakis NP, Bader HN, Makotkine I, Chattopadhyay M, Xu C, Buxbaum Grice A, Tocheva AS, Flory JD, Buxbaum JD, Meaney MJ, Brennand K, Yehuda R. Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development. Translational Psychiatry. 9: 201. PMID 31434874 DOI: 10.1038/S41398-019-0539-X  0.738
2019 Domingo-Fernández D, Provost A, Kodamullil AT, Marín-Llaó J, Lasseter H, Diaz K, Daskalakis NP, Lancashire L, Hofmann-Apitius M, Haas M. PTSD Biomarker Database: deep dive metadatabase for PTSD biomarkers, visualizations and analysis tools. Database : the Journal of Biological Databases and Curation. 2019. PMID 31260040 DOI: 10.1093/Database/Baz081  0.35
2019 Huckins L, Breen M, van Rooij S, Hartmann J, Girdhar K, Jovanovic T, Nievergelt C, Im HK, Buxbaum J, Sklar P, Ressler K, Stahl E, Daskalakis N. GENETICALLY REGULATED GENE EXPRESSION IN BRAIN AND PERIPHERAL TISSUES IN PTSD European Neuropsychopharmacology. 29: S1056. DOI: 10.1016/J.Euroneuro.2018.07.072  0.68
2019 Huckins L, Girdhar K, Dobbyn A, Jovanovic T, Nievergelt C, Hoffman G, Maihofer A, Stein M, Sklar P, Ressler K, Buxbaum J, Stahl E, Daskalakis N. Genetically Predicted Gene Expression In The Brain And Peripheral Tissues Associates With Ptsd European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.200  0.708
2019 Daskalakis N, Haas M, Lancashire L. T155. Variational Autoencoder Identifies Clinically Meaningful Latent Features in Neurodegeneration and Neuropsychiatry Based on Blood Gene Expression and Genetically Regulated Gene Expression Across Tissue-Types Biological Psychiatry. 85. DOI: 10.1016/J.Biopsych.2019.03.478  0.311
2019 Li Y, Michopoulos V, Lori A, Lott A, Bradley B, Jovanovic T, Ressler K, Kellis M, Daskalakis N. 200. Dissecting the Transcriptomic and Phenotypic Complexity of PTSD With Transcriptomic Imputation and Bayesian Machine Learning Biological Psychiatry. 85: S83. DOI: 10.1016/J.Biopsych.2019.03.214  0.57
2019 Logue M, Wolf E, Morrison F, Zhou Z, Smith A, Daskalakis NP, Stone A, Schichman S, McGlinchey R, Milberg W, Huber B, Miller M. 28. An Epigenome-Wide Association Study of PTSD in Veterans Implicates Several New DNA Methylation Loci Biological Psychiatry. 85: S12. DOI: 10.1016/J.Biopsych.2019.03.042  0.324
2018 Vaz-Silva J, Gomes P, Jin Q, Zhu M, Zhuravleva V, Quintremil S, Meira T, Silva J, Dioli C, Soares-Cunha C, Daskalakis NP, Sousa N, Sotiropoulos I, Waites CL. Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction. The Embo Journal. PMID 30166454 DOI: 10.15252/Embj.201899084  0.308
2018 McCullough KM, Daskalakis NP, Gafford G, Morrison FG, Ressler KJ. Cell-type-specific interrogation of CeA Drd2 neurons to identify targets for pharmacological modulation of fear extinction. Translational Psychiatry. 8: 164. PMID 30135420 DOI: 10.1038/S41398-018-0190-Y  0.588
2018 Daskalakis NP, Rijal CM, King C, Huckins LM, Ressler KJ. Recent Genetics and Epigenetics Approaches to PTSD. Current Psychiatry Reports. 20: 30. PMID 29623448 DOI: 10.1007/S11920-018-0898-7  0.649
2018 Daskalakis NP, Provost AC, Hunter RG, Guffanti G. Noncoding RNAs: Stress, Glucocorticoids, and Posttraumatic Stress Disorder. Biological Psychiatry. PMID 29559087 DOI: 10.1016/J.Biopsych.2018.01.009  0.438
2018 Wingo A, Klengel T, Daskalakis NP, Breen M, Lori A, Tharp G, Innocente B, Wingo T, Gillespie C, Jovanovic T, Gibson G, Bradley B, Jin P, Ressler K. T25. Genome-Wide MicroRNA Expression Analysis of PTSD With Comorbid Depression: A Meta-Analysis of Civilian and Veteran Datasets Biological Psychiatry. 83: S138. DOI: 10.1016/J.Biopsych.2018.02.361  0.58
2018 Wingo A, Daskalakis N, Galatzer-Levy I, Richholt R, Michopoulos V, Lori A, Guffanti G, Rothbaum B, Jovanovic T, Myers A, Huentelman M, Nemeroff C, Ressler K. 228. Transcriptome-Wide Analysis Identifies ICAM5 Differentially Expressed in Chronic PTSD Symptoms Versus Resiliency Post Trauma Exposure in a Longitudinal Study Biological Psychiatry. 83: S91-S92. DOI: 10.1016/J.Biopsych.2018.02.247  0.619
2018 Daskalakis N, Ressler K. 217. Integrative Systems Approach Identifies HPA-Axis Related Gene Networks in PTSD Biological Psychiatry. 83: S87. DOI: 10.1016/J.Biopsych.2018.02.236  0.593
2017 Schür RR, Boks MP, Rutten BPF, Daskalakis NP, de Nijs L, van Zuiden M, Kavelaars A, Heijnen CJ, Joëls M, Kahn RS, Geuze E, Vermetten E, Vinkers CH. Longitudinal changes in glucocorticoid receptor exon 1F methylation and psychopathology after military deployment. Translational Psychiatry. 7: e1181. PMID 28742078 DOI: 10.1016/J.Euroneuro.2016.09.550  0.334
2017 Rutten BPF, Vermetten E, Vinkers CH, Ursini G, Daskalakis NP, Pishva E, de Nijs L, Houtepen LC, Eijssen L, Jaffe AE, Kenis G, Viechtbauer W, van den Hove D, Schraut KG, Lesch KP, et al. Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder. Molecular Psychiatry. PMID 28630453 DOI: 10.1038/Mp.2017.120  0.571
2017 Harony-Nicolas H, Kay M, Hoffmann JD, Klein ME, Bozdagi-Gunal O, Riad M, Daskalakis NP, Sonar S, Castillo PE, Hof PR, Shapiro ML, Baxter MG, Wagner S, Buxbaum JD. Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat. Elife. 6. PMID 28139198 DOI: 10.7554/Elife.18904  0.496
2017 Wagner S, Harony-Nicolas H, Kay M, du Hoffmann J, Bozdagi-Gunal O, Klein M, Riad M, Daskalakis N, Castillo P, Hof P, Shapiro M, Baxter M, Buxbaum J. Oxytocin Improves Social And Attentional Deficits In A Novel Genetically Modified Rat Model of Autism European Neuropsychopharmacology. 27: S422. DOI: 10.1016/J.Euroneuro.2016.09.473  0.451
2017 Daskalakis N. 424. Genomic Mediators of PTSD in Blood and Brain Biological Psychiatry. 81: S173. DOI: 10.1016/J.Biopsych.2017.02.908  0.323
2017 Daskalakis N. 697. Testing the Three-Hit Hypothesis of Stress Susceptibility and Resilience in the Rat Biological Psychiatry. 81: S282-S283. DOI: 10.1016/J.Biopsych.2017.02.764  0.36
2017 Feder A, Pietrzak R, Diab O, Cancelmo L, Yehuda R, Bierer LM, Daskalakis NP, Ratanatharathorn A, Koenen K, Southwick SM. 347. An Integrative Psychobiological Model of Resilience in World Trade Center Responders Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.364  0.43
2017 Yehuda R, Bierer LM, Flory JD, Daskalakis NP, Bader HN. 344. FKBP5 Methylation: Stable Trait or Fluctuating State? Biological Psychiatry. 81: S141. DOI: 10.1016/J.Biopsych.2017.02.361  0.435
2017 Yehuda R, Bierer LM, Bader HN, Daskalakis NP, Klengel T, Binder E. 90. Second Generation Effects of Trauma: Evidence for Developmental Programming Biological Psychiatry. 81: S38. DOI: 10.1016/J.Biopsych.2017.02.102  0.572
2016 Daskalakis NP, Cohen H, Nievergelt CM, Baker DG, Buxbaum JD, Russo SJ, Yehuda R. New translational perspectives for blood-based biomarkers of PTSD: From glucocorticoid to immune mediators of stress susceptibility. Experimental Neurology. PMID 27481726 DOI: 10.1016/J.Expneurol.2016.07.024  0.683
2016 Harony-Nicolas H, Kay M, Hoffmann Jd, Klein ME, Bozdagi-Gunal O, Riad M, Daskalakis NP, Sonar S, Castillo PE, Hof PR, Shapiro ML, Baxter MG, Wagner S, Buxbaum JD. Author response: Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient rat Elife. DOI: 10.7554/Elife.18904.017  0.445
2016 Daskalakis NP. Integrative systems biology approach to identify novel glucocorticoid-based biomarkers and treatment targets for PTSD Psychoneuroendocrinology. 71: 71. DOI: 10.1016/J.Psyneuen.2016.07.185  0.302
2016 Daskalakis NP. Epigenetic regulation in association with treatment response in PTSD Psychoneuroendocrinology. 71: 10-11. DOI: 10.1016/J.Psyneuen.2016.07.037  0.355
2015 Daskalakis NP, De Kloet ER, Yehuda R, Malaspina D, Kranz TM. Early Life Stress Effects on Glucocorticoid-BDNF Interplay in the Hippocampus. Frontiers in Molecular Neuroscience. 8: 68. PMID 26635521 DOI: 10.3389/Fnmol.2015.00068  0.795
2015 Hammels C, Pishva E, De Vry J, van den Hove DL, Prickaerts J, van Winkel R, Selten JP, Lesch KP, Daskalakis NP, Steinbusch HW, van Os J, Kenis G, Rutten BP. Defeat stress in rodents: From behavior to molecules. Neuroscience and Biobehavioral Reviews. 59: 111-140. PMID 26475995 DOI: 10.1016/J.Neubiorev.2015.10.006  0.405
2015 Yehuda R, Daskalakis NP, Bierer LM, Bader HN, Klengel T, Holsboer F, Binder EB. Holocaust Exposure Induced Intergenerational Effects on FKBP5 Methylation. Biological Psychiatry. PMID 26410355 DOI: 10.1016/J.Biopsych.2015.08.005  0.675
2015 Daskalakis NP, Binder EB. Schizophrenia in the spectrum of gene-stress interactions: the FKBP5 example. Schizophrenia Bulletin. 41: 323-9. PMID 25592294 DOI: 10.1093/Schbul/Sbu189  0.519
2015 Yehuda R, Flory JD, Bierer LM, Henn-Haase C, Lehrner A, Desarnaud F, Makotkine I, Daskalakis NP, Marmar CR, Meaney MJ. Lower methylation of glucocorticoid receptor gene promoter 1F in peripheral blood of veterans with posttraumatic stress disorder. Biological Psychiatry. 77: 356-64. PMID 24661442 DOI: 10.1016/J.Biopsych.2014.02.006  0.676
2014 Daskalakis NP, Yehuda R. Early maternal influences on stress circuitry: implications for resilience and susceptibility to physical and mental disorders. Frontiers in Endocrinology. 5: 244. PMID 25642210 DOI: 10.3389/Fendo.2014.00244  0.627
2014 Daskalakis NP, Yehuda R. Site-specific methylation changes in the glucocorticoid receptor exon 1F promoter in relation to life adversity: systematic review of contributing factors. Frontiers in Neuroscience. 8: 369. PMID 25484853 DOI: 10.3389/Fnins.2014.00369  0.546
2014 Daskalakis NP, Enthoven L, Schoonheere E, de Kloet ER, Oitzl MS. Immediate Effects of Maternal Deprivation on the (Re)Activity of the HPA-Axis Differ in CD1 and C57Bl/6J Mouse Pups. Frontiers in Endocrinology. 5: 190. PMID 25414695 DOI: 10.3389/Fendo.2014.00190  0.775
2014 Yehuda R, Pratchett LC, Elmes MW, Lehrner A, Daskalakis NP, Koch E, Makotkine I, Flory JD, Bierer LM. Glucocorticoid-related predictors and correlates of post-traumatic stress disorder treatment response in combat veterans. Interface Focus. 4: 20140048. PMID 25285201 DOI: 10.1098/Rsfs.2014.0048  0.575
2014 Daskalakis NP, Yehuda R. Principles for developing animal models of military PTSD. European Journal of Psychotraumatology. 5. PMID 25206946 DOI: 10.3402/Ejpt.V5.23825  0.59
2014 Daskalakis NP, Cohen H, Cai G, Buxbaum JD, Yehuda R. Expression profiling associates blood and brain glucocorticoid receptor signaling with trauma-related individual differences in both sexes. Proceedings of the National Academy of Sciences of the United States of America. 111: 13529-34. PMID 25114262 DOI: 10.1073/Pnas.1401660111  0.681
2014 Bader HN, Bierer LM, Lehrner A, Makotkine I, Daskalakis NP, Yehuda R. Maternal Age at Holocaust Exposure and Maternal PTSD Independently Influence Urinary Cortisol Levels in Adult Offspring. Frontiers in Endocrinology. 5: 103. PMID 25071719 DOI: 10.3389/Fendo.2014.00103  0.571
2014 Bierer LM, Bader HN, Daskalakis NP, Lehrner AL, Makotkine I, Seckl JR, Yehuda R. Elevation of 11β-hydroxysteroid dehydrogenase type 2 activity in Holocaust survivor offspring: evidence for an intergenerational effect of maternal trauma exposure. Psychoneuroendocrinology. 48: 1-10. PMID 24971590 DOI: 10.1016/J.Psyneuen.2014.06.001  0.541
2014 Yehuda R, Daskalakis NP, Lehrner A, Desarnaud F, Bader HN, Makotkine I, Flory JD, Bierer LM, Meaney MJ. Influences of maternal and paternal PTSD on epigenetic regulation of the glucocorticoid receptor gene in Holocaust survivor offspring. The American Journal of Psychiatry. 171: 872-80. PMID 24832930 DOI: 10.1176/Appi.Ajp.2014.13121571  0.64
2014 Lehrner A, Bierer LM, Passarelli V, Pratchett LC, Flory JD, Bader HN, Harris IR, Bedi A, Daskalakis NP, Makotkine I, Yehuda R. Maternal PTSD associates with greater glucocorticoid sensitivity in offspring of Holocaust survivors. Psychoneuroendocrinology. 40: 213-20. PMID 24485493 DOI: 10.1016/J.Psyneuen.2013.11.019  0.577
2014 Daskalakis NP, Diamantopoulou A, Claessens SE, Remmers E, Tjälve M, Oitzl MS, Champagne DL, de Kloet ER. Early experience of a novel-environment in isolation primes a fearful phenotype characterized by persistent amygdala activation. Psychoneuroendocrinology. 39: 39-57. PMID 24275003 DOI: 10.1016/J.Psyneuen.2013.09.021  0.774
2013 Yehuda R, Daskalakis NP, Desarnaud F, Makotkine I, Lehrner AL, Koch E, Flory JD, Buxbaum JD, Meaney MJ, Bierer LM. Epigenetic Biomarkers as Predictors and Correlates of Symptom Improvement Following Psychotherapy in Combat Veterans with PTSD. Frontiers in Psychiatry. 4: 118. PMID 24098286 DOI: 10.3389/Fpsyt.2013.00118  0.696
2013 Daskalakis NP, Lehrner A, Yehuda R. Endocrine aspects of post-traumatic stress disorder and implications for diagnosis and treatment. Endocrinology and Metabolism Clinics of North America. 42: 503-13. PMID 24011883 DOI: 10.1016/J.Ecl.2013.05.004  0.587
2013 Daskalakis NP, Yehuda R, Diamond DM. Animal models in translational studies of PTSD. Psychoneuroendocrinology. 38: 1895-911. PMID 23845512 DOI: 10.1016/J.Psyneuen.2013.06.006  0.588
2013 Daskalakis NP, Bagot RC, Parker KJ, Vinkers CH, de Kloet ER. The three-hit concept of vulnerability and resilience: toward understanding adaptation to early-life adversity outcome. Psychoneuroendocrinology. 38: 1858-73. PMID 23838101 DOI: 10.1016/J.Psyneuen.2013.06.008  0.749
2012 Claessens SE, Daskalakis NP, Oitzl MS, de Kloet ER. Early handling modulates outcome of neonatal dexamethasone exposure. Hormones and Behavior. 62: 433-41. PMID 22892314 DOI: 10.1016/J.Yhbeh.2012.07.011  0.778
2012 Daskalakis NP, Oitzl MS, Schächinger H, Champagne DL, de Kloet ER. Testing the cumulative stress and mismatch hypotheses of psychopathology in a rat model of early-life adversity. Physiology & Behavior. 106: 707-21. PMID 22306534 DOI: 10.1016/J.Physbeh.2012.01.015  0.8
2012 Daskalakis NP, Buxbaum J, Flory JD, Cai G, Shen L, Bierer LM, Cohen H, Yehuda R. Brain and blood gene expression pathways associated with susceptibility to PTSD European Journal of Psychotraumatology. 3. DOI: 10.3402/Ejpt.V3I0.19509  0.63
2012 Kloet ERd, Daskalakis NP. Early life stress concept: introduction European Journal of Psychotraumatology. 3. DOI: 10.3402/Ejpt.V3I0.19461  0.363
2012 Daskalakis NP, Kloet ERd. Animal model of differential susceptibility to stress in development: implications for schizophrenia European Journal of Psychotraumatology. 3. DOI: 10.3402/Ejpt.V3I0.19446  0.312
2011 Daskalakis NP, Claessens SE, Laboyrie JJ, Enthoven L, Oitzl MS, Champagne DL, de Kloet ER. The newborn rat's stress system readily habituates to repeated and prolonged maternal separation, while continuing to respond to stressors in context dependent fashion. Hormones and Behavior. 60: 165-76. PMID 21570400 DOI: 10.1016/J.Yhbeh.2011.04.003  0.758
2011 Claessens SE, Daskalakis NP, van der Veen R, Oitzl MS, de Kloet ER, Champagne DL. Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences. Psychopharmacology. 214: 141-54. PMID 21165737 DOI: 10.1007/S00213-010-2118-Y  0.786
2011 Richter S, Schulz A, Zech CM, Oitzl MS, Daskalakis NP, Blumenthal TD, Schächinger H. Cortisol rapidly disrupts prepulse inhibition in healthy men. Psychoneuroendocrinology. 36: 109-14. PMID 20685043 DOI: 10.1016/J.Psyneuen.2010.07.002  0.639
2011 Daskalakis N, Martens G, Cools A, de Kloet E. P.4.009 Schizophrenia endophenotypes and stress hyper-reactivity co-precipitate following adverse life events in genetically susceptible rats European Neuropsychopharmacology. 21: S85-S86. DOI: 10.1016/S0924-977X(11)70098-0  0.347
2010 Daskalakis N, Fung W, Schnorr S, Meelis W, Oitzl M, Kloet E. [P2.34]: The three hit hypothesis of schizophrenia tested in genetically selected rats exposed to early life experience and adolescent psycho‐social stressor International Journal of Developmental Neuroscience. 28: 698-698. DOI: 10.1016/J.Ijdevneu.2010.07.164  0.558
2009 Daskalakis NP, Kaperoni M, Koros C, de Kloet ER, Kitraki E. Environmental and tactile stimulation modulates the neonatal handling effect on adult rat spatial memory. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 27: 747-55. PMID 19720127 DOI: 10.1016/J.Ijdevneu.2009.08.013  0.709
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