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R. Blake Hill - Publications

Affiliations: 
2000-2012 Johns Hopkins University, Baltimore, MD 
 2012- Medical College of Wisconsin, Milwaukee, WI, United States 
Area:
General Biophysics, Biochemistry
Website:
https://www.mcw.edu/departments/biochemistry/faculty/blake-hill-phd
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47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nolden KA, Harwig MC, Hill RB. Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission. The Journal of Biological Chemistry. 105380. PMID 37866629 DOI: 10.1016/j.jbc.2023.105380  0.319
2023 Posey AE, Ross KA, Bagheri M, Lanum EN, Khan MA, Jennings CE, Harwig MC, Kennedy NW, Hilser VJ, Harden JL, Hill RB. The variable domain from dynamin-related protein 1 promotes liquid-liquid phase separation that enhances its interaction with cardiolipin-containing membranes. Protein Science : a Publication of the Protein Society. e4787. PMID 37743569 DOI: 10.1002/pro.4787  0.32
2023 Nolden KA, Harwig MC, Hill RB. Human Fis1 directly interacts with Drp1 in an evolutionarily conserved manner to promote mitochondrial fission. Biorxiv : the Preprint Server For Biology. PMID 37205551 DOI: 10.1101/2023.05.03.539292  0.323
2022 Egner JM, Nolden KA, Harwig MC, Bonate RP, De Anda J, Tessmer MH, Noey EL, Ihenacho UK, Liu Z, Peterson FC, Wong GCL, Widlansky ME, Hill RB. Structural studies of human fission protein FIS1 reveal a dynamic region important for GTPase DRP1 recruitment and mitochondrial fission. The Journal of Biological Chemistry. 102620. PMID 36272645 DOI: 10.1016/j.jbc.2022.102620  0.326
2022 Nolden KA, Egner JM, Collier JJ, Russell OM, Alston CL, Harwig MC, Widlansky ME, Sasorith S, Barbosa IA, Douglas AG, Baptista J, Walker M, Donnelly DE, Morris AA, Tan HJ, ... ... Hill RB, et al. Novel variants impair mitochondrial dynamics through divergent mechanisms. Life Science Alliance. 5. PMID 35914810 DOI: 10.26508/lsa.202101284  0.332
2020 Kennedy NW, Picton LK, Hill RB. Isolation and Analysis of Mitochondrial Fission Enzyme DNM1 from Saccharomyces cerevisiae. Methods in Molecular Biology (Clifton, N.J.). 2159: 3-15. PMID 32529359 DOI: 10.1007/978-1-0716-0676-6_1  0.722
2018 Boyle KA, Van Wickle J, Hill RB, Marchese A, Kalyanaraman B, Dwinell MB. Mitochondria-targeted drugs stimulate mitophagy and abrogate colon cancer cell proliferation. The Journal of Biological Chemistry. PMID 30087121 DOI: 10.1074/Jbc.Ra117.001469  0.323
2018 Harwig MC, Viana MP, Egner JM, Harwig JJ, Widlansky ME, Rafelski SM, Hill RB. Methods for imaging mammalian mitochondrial morphology: A prospective on MitoGraph. Analytical Biochemistry. PMID 29505779 DOI: 10.1016/J.Ab.2018.02.022  0.354
2018 Ma C, Beyer AM, Durand M, Clough AV, Zhu D, Norwood Toro L, Terashvili M, Ebben JD, Hill RB, Audi SH, Medhora M, Jacobs ER. Hyperoxia Causes Mitochondrial Fragmentation in Pulmonary Endothelial Cells by Increasing Expression of Pro-Fission Proteins. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29419407 DOI: 10.1161/Atvbaha.117.310605  0.336
2017 Egner JM, Jensen DR, Olp MD, Kennedy NW, Volkman BF, Peterson FC, Smith BC, Hill RB. Development and Validation of 2D Difference Intensity Analysis for Chemical Library Screening by Protein-Detected NMR. Chembiochem : a European Journal of Chemical Biology. PMID 29239081 DOI: 10.1002/Cbic.201700386  0.309
2017 Lee MW, Lee EY, Lai GH, Kennedy NW, Posey AE, Xian W, Ferguson AL, Hill RB, Wong GCL. Molecular Motor Dnm1 Synergistically Induces Membrane Curvature To Facilitate Mitochondrial Fission. Acs Central Science. 3: 1156-1167. PMID 29202017 DOI: 10.1021/Acscentsci.7B00338  0.478
2017 Bakkum AL, Hill RB. Removal of a consensus proline is not sufficient to allow tetratricopeptide repeat oligomerization. Protein Science : a Publication of the Protein Society. PMID 28707340 DOI: 10.1002/Pro.3234  0.428
2017 Bordt EA, Clerc P, Roelofs BA, Saladino AJ, Tretter L, Adam-Vizi V, Cherok E, Khalil A, Yadava N, Ge SX, Francis TC, Kennedy NW, Picton LK, Kumar T, Uppuluri S, ... Hill RB, et al. The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species. Developmental Cell. 40: 583-594.e6. PMID 28350990 DOI: 10.1016/J.Devcel.2017.02.020  0.706
2016 Koppenol-Raab M, Harwig MC, Posey AE, Egner JM, MacKenzie KR, Hill RB. A Targeted Mutation Identified Through pKa Measurements Indicates a Post-recruitment Role for Fis1 in Yeast Mitochondrial Fission. The Journal of Biological Chemistry. PMID 27496949 DOI: 10.1074/Jbc.M116.724005  0.753
2016 Woodrum BW, Maxwell J, Allen DM, Wilson J, Krumpe LR, Bobkov AA, Hill RB, Kibler KV, O'Keefe BR, Ghirlanda G. A Designed "Nested" Dimer of Cyanovirin-N Increases Antiviral Activity. Viruses. 8. PMID 27275831 DOI: 10.3390/V8060158  0.56
2016 Bakkum A, Egner J, Harwig MC, Bierer D, Hill RB. Structural Studies on the Mitochondrial Fission Protein Fis1 Suggest a Mechanism of TPR Protein Self-Association Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.299  0.479
2015 Hill RB, MacKenzie KR, Harwig MC. The Tail-End Is Only the Beginning: NMR Study Reveals a Membrane-Bound State of BCL-XL. Journal of Molecular Biology. 427: 2257-61. PMID 25896456 DOI: 10.1016/J.Jmb.2015.04.005  0.382
2014 Diers AR, Broniowska KA, Chang CF, Hill RB, Hogg N. S-Nitrosation of monocarboxylate transporter 1: inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells. Free Radical Biology & Medicine. 69: 229-38. PMID 24486553 DOI: 10.1016/J.Freeradbiomed.2014.01.031  0.314
2012 Lees JP, Manlandro CM, Picton LK, Tan AZ, Casares S, Flanagan JM, Fleming KG, Hill RB. A designed point mutant in Fis1 disrupts dimerization and mitochondrial fission. Journal of Molecular Biology. 423: 143-58. PMID 22789569 DOI: 10.1016/J.Jmb.2012.06.042  0.762
2011 Tooley JE, Khangulov V, Lees JP, Schlessman JL, Bewley MC, Heroux A, Bosch J, Hill RB. The 1.75 Å resolution structure of fission protein Fis1 from Saccharomyces cerevisiae reveals elusive interactions of the autoinhibitory domain. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1310-5. PMID 22102223 DOI: 10.1107/S1744309111029368  0.711
2011 Wells RC, Hill RB. The cytosolic domain of Fis1 binds and reversibly clusters lipid vesicles. Plos One. 6: e21384. PMID 21738650 DOI: 10.1371/Journal.Pone.0021384  0.444
2011 Tan FJ, Zuckerman JE, Wells RC, Hill RB. The C. elegans B-cell lymphoma 2 (Bcl-2) homolog cell death abnormal 9 (CED-9) associates with and remodels LIPID membranes. Protein Science : a Publication of the Protein Society. 20: 62-74. PMID 21031486 DOI: 10.1002/Pro.536  0.474
2010 Chang CR, Manlandro CM, Arnoult D, Stadler J, Posey AE, Hill RB, Blackstone C. A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division. The Journal of Biological Chemistry. 285: 32494-503. PMID 20696759 DOI: 10.1074/Jbc.M110.142430  0.412
2010 Hill RB, Pellegrini L. The PARL family of mitochondrial rhomboid proteases. Seminars in Cell & Developmental Biology. 21: 582-92. PMID 20045481 DOI: 10.1016/J.Semcdb.2009.12.011  0.438
2009 Picton LK, Casares S, Monahan AC, Majumdar A, Hill RB. Evidence for conformational heterogeneity of fission protein Fis1 from Saccharomyces cerevisiae. Biochemistry. 48: 6598-609. PMID 19522466 DOI: 10.1021/Bi802221H  0.744
2009 Parrott MM, Sitarski SA, Arnold RJ, Picton LK, Hill RB, Mukhopadhyay S. Role of conserved cysteines in the alphavirus E3 protein. Journal of Virology. 83: 2584-91. PMID 19109378 DOI: 10.1128/Jvi.02158-08  0.695
2008 Tan FJ, Husain M, Manlandro CM, Koppenol M, Fire AZ, Hill RB. CED-9 and mitochondrial homeostasis in C. elegans muscle Journal of Cell Science. 121: 3373-3382. PMID 18827010 DOI: 10.1242/Jcs.032904  0.391
2008 De Cotiis DA, Woll MP, Fox TE, Hill RB, Levenson R, Flanagan JM. Optimized expression and purification of myristoylated human neuronal calcium sensor 1 in E. coli. Protein Expression and Purification. 61: 103-12. PMID 18634883 DOI: 10.1016/J.Pep.2008.06.006  0.313
2008 Siskind LJ, Feinstein L, Yu T, Davis JS, Jones D, Choi J, Zuckerman JE, Tan W, Hill RB, Hardwick JM, Colombini M. Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels. The Journal of Biological Chemistry. 283: 6622-30. PMID 18171672 DOI: 10.1074/Jbc.M706115200  0.4
2007 Wells RC, Picton LK, Williams SC, Tan FJ, Hill RB. Direct binding of the dynamin-like GTPase, Dnm1, to mitochondrial dynamics protein Fis1 is negatively regulated by the Fis1 N-terminal arm. The Journal of Biological Chemistry. 282: 33769-75. PMID 17884824 DOI: 10.1074/Jbc.M700807200  0.735
2007 Tan FJ, Fire AZ, Hill RB. Regulation of apoptosis by C. elegans CED-9 in the absence of the C-terminal transmembrane domain Cell Death and Differentiation. 14: 1925-1935. PMID 17703231 DOI: 10.1038/Sj.Cdd.4402215  0.324
2006 Thuduppathy GR, Terrones O, Craig JW, Basañez G, Hill RB. The N-terminal domain of Bcl-xL reversibly binds membranes in a pH-dependent manner. Biochemistry. 45: 14533-42. PMID 17128992 DOI: 10.1021/Bi0616652  0.756
2006 Thuduppathy GR, Craig JW, Kholodenko V, Schon A, Hill RB. Evidence that Membrane Insertion of the Cytosolic Domain of Bcl-xL is Governed by an Electrostatic Mechanism Journal of Molecular Biology. 359: 1045-1058. PMID 16650855 DOI: 10.1016/J.Jmb.2006.03.052  0.762
2006 Thuduppathy GR, Hill RB. Acid destabilization of the solution conformation of Bcl-xL does not drive its pH-dependent insertion into membranes. Protein Science : a Publication of the Protein Society. 15: 248-57. PMID 16385002 DOI: 10.1110/Ps.051807706  0.751
2004 Fannjiang Y, Cheng WC, Lee SJ, Qi B, Pevsner J, McCaffery JM, Hill RB, Basañez G, Hardwick JM. Mitochondrial fission proteins regulate programmed cell death in yeast. Genes & Development. 18: 2785-97. PMID 15520274 DOI: 10.1101/Gad.1247904  0.334
2004 Thuduppathy GR, Hill RB. Applications of NMR spin relaxation methods for measuring biological motions. Methods in Enzymology. 384: 243-64. PMID 15081691 DOI: 10.1016/S0076-6879(04)84015-1  0.71
2004 Dohm JA, Lee SJ, Hardwick JM, Hill RB, Gittis AG. Cytosolic domain of the human mitochondrial fission protein fis1 adopts a TPR fold. Proteins. 54: 153-6. PMID 14705031 DOI: 10.1002/Prot.10524  0.482
2001 Hill RB, Raleigh DP, Lombardi A, Degrado WF. ChemInform Abstract: De novo Design of Helical Bundles as Models for Understanding Protein Folding and Function Cheminform. 32: no-no. DOI: 10.1002/chin.200106253  0.582
2000 Hill RB, Raleigh DP, Lombardi A, Degrado WF. De novo design of helical bundles as models for understanding protein folding and function Accounts of Chemical Research. 33: 745-754. PMID 11087311 DOI: 10.1021/Ar970004H  0.625
2000 Hill RB, DeGrado WF. A polar, solvent-exposed residue can be essential for native protein structure. Structure (London, England : 1993). 8: 471-9. PMID 10801493 DOI: 10.1016/S0969-2126(00)00130-1  0.521
2000 Hill RB, Hong JK, DeGrado WF. Hydrogen bonded cluster can specify the native state of a protein [18] Journal of the American Chemical Society. 122: 746-747. DOI: 10.1021/Ja9919332  0.434
2000 Hill RB, Bracken C, Degrado WF, Palmer AG. Molecular motions and protein folding: Characterization of the backbone dynamics and folding equilibrium of α2D using 13C NMR spin relaxation Journal of the American Chemical Society. 122: 11610-11619. DOI: 10.1021/Ja001129B  0.51
1999 Lally ET, Hill RB, Kieba IR, Korostoff J. The interaction between RTX toxins and target cells. Trends in Microbiology. 7: 356-361. PMID 10470043 DOI: 10.1016/S0966-842X(99)01530-9  0.319
1995 Hill RB, Mackenzie KR, Flanagan JM, Cronan JE, Prestegard JH. Overexpression, Purification, and Characterization of Escherichia coli Acyl Carrier Protein and 2 Mutant Proteins Protein Expression and Purification. 6: 394-400. PMID 8527922 DOI: 10.1006/Prep.1995.1052  0.472
1995 Hill RB, Flanagan JM, Prestegard JH. 1H and 15N magnetic resonance assignments, secondary structure, and tertiary fold of escherichia coli DnaJ(1-78) Biochemistry. 34: 5587-5596. PMID 7727420 DOI: 10.1021/Bi00016A033  0.53
1995 Andrec M, Hill RB, Prestegard JH. Amide exchange rates in Escherichia coli acyl carrier protein: Correlation with protein structure and dynamics Protein Science. 4: 983-993. PMID 7663354 DOI: 10.1002/Pro.5560040518  0.561
1993 Kriwacki RW, Hill RB, Flanagan JM, Caradonna JP, Prestegard JH. New NMR methods for the characterization of bound waters in macromolecules Journal of the American Chemical Society. 115: 8907-8911. DOI: 10.1021/Ja00073A003  0.486
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