| Year |
Citation |
Score |
| 2019 |
Daniels SR, Liyasova M, Kales SC, Nau MM, Ryan PE, Green JE, Lipkowitz S. Loss of function Cbl-c mutations in solid tumors. Plos One. 14: e0219143. PMID 31260484 DOI: 10.1371/journal.pone.0219143 |
0.544 |
|
| 2019 |
Liyasova MS, Ma K, Voeller D, Ryan PE, Chen J, Klevit RE, Lipkowitz S. Cbl interacts with multiple E2s in vitro and in cells. Plos One. 14: e0216967. PMID 31120930 DOI: 10.1371/Journal.Pone.0216967 |
0.525 |
|
| 2015 |
Li M, Kales SC, Ma K, Shoemaker B, Crespo-Barreto J, Cangelosi A, Lipkowitz S, Panchenko A. Balancing protein stability and activity in cancer: a new approach for identifying driver mutations affecting CBL ubiquitin ligase activation. Cancer Research. PMID 26676746 DOI: 10.1158/0008-5472.Can-14-3812 |
0.356 |
|
| 2015 |
Liyasova MS, Ma K, Lipkowitz S. Molecular pathways: cbl proteins in tumorigenesis and antitumor immunity-opportunities for cancer treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1789-94. PMID 25477533 DOI: 10.1158/1078-0432.CCR-13-2490 |
0.417 |
|
| 2014 |
Kales SC, Nau MM, Merchant AS, Lipkowitz S. Enigma prevents Cbl-c-mediated ubiquitination and degradation of RETMEN2A Plos One. 9. PMID 24466333 DOI: 10.1371/journal.pone.0087116 |
0.412 |
|
| 2013 |
Ma K, Kales SC, Nau MM, Lipkowitz S. Cbl as a master regulator of receptor tyrosine Kinase trafficking Vesicle Trafficking in Cancer. 2147483647: 219-244. DOI: 10.1007/978-1-4614-6528-7_11 |
0.48 |
|
| 2012 |
Ryan PE, Kales SC, Yadavalli R, Nau MM, Zhang H, Lipkowitz S. Cbl-c ubiquitin ligase activity is increased via the interaction of its RING finger domain with a LIM domain of the paxillin homolog, Hic 5. Plos One. 7: e49428. PMID 23145173 DOI: 10.1371/journal.pone.0049428 |
0.541 |
|
| 2012 |
Kales SC, Ryan PE, Lipkowitz S. Cbl exposes its RING finger. Nature Structural & Molecular Biology. 19: 131-3. PMID 22301873 DOI: 10.1038/nsmb.2241 |
0.383 |
|
| 2011 |
Lipkowitz S, Weissman AM. RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis Nature Reviews Cancer. 11: 629-643. PMID 21863050 DOI: 10.1038/nrc3120 |
0.356 |
|
| 2010 |
Ryan PE, Sivadasan-Nair N, Nau MM, Nicholas S, Lipkowitz S. The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme Journal of Biological Chemistry. 285: 23687-23698. PMID 20525694 DOI: 10.1074/jbc.M109.091157 |
0.54 |
|
| 2010 |
Kales SC, Ryan PE, Nau MM, Lipkowitz S. Cbl and human myeloid neoplasms: the Cbl oncogene comes of age. Cancer Research. 70: 4789-94. PMID 20501843 DOI: 10.1158/0008-5472.CAN-10-0610 |
0.522 |
|
| 2007 |
Peschard P, Kozlov G, Lin T, Mirza IA, Berghuis AM, Lipkowitz S, Park M, Gehring K. Structural basis for ubiquitin-mediated dimerization and activation of the ubiquitin protein ligase Cbl-b. Molecular Cell. 27: 474-85. PMID 17679095 DOI: 10.1016/J.Molcel.2007.06.023 |
0.375 |
|
| 2006 |
Davies GC, Ryan PE, Rahman L, Zajac-Kaye M, Lipkowitz S. EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins. Oncogene. 25: 6497-509. PMID 16702950 DOI: 10.1038/sj.onc.1209662 |
0.548 |
|
| 2006 |
Ryan PE, Davies GC, Nau MM, Lipkowitz S. Regulating the regulator: negative regulation of Cbl ubiquitin ligases. Trends in Biochemical Sciences. 31: 79-88. PMID 16406635 DOI: 10.1016/j.tibs.2005.12.004 |
0.478 |
|
| 2005 |
Zeng S, Xu Z, Lipkowitz S, Longley JB. Regulation of stem cell factor receptor signaling by Cbl family proteins (Cbl-b/c-Cbl). Blood. 105: 226-32. PMID 15315962 DOI: 10.1182/Blood-2004-05-1768 |
0.437 |
|
| 2004 |
Davies GC, Ettenberg SA, Coats AO, Mussante M, Ravichandran S, Collins J, Nau MM, Lipkowitz S. Cbl-b interacts with ubiquitinated proteins; differential functions of the UBA domains of c-Cbl and Cbl-b. Oncogene. 23: 7104-15. PMID 15273720 DOI: 10.1038/sj.onc.1207952 |
0.419 |
|
| 2004 |
Peschard P, Ishiyama N, Lin T, Lipkowitz S, Park M. A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation. The Journal of Biological Chemistry. 279: 29565-71. PMID 15123609 DOI: 10.1074/Jbc.M403954200 |
0.376 |
|
| 2003 |
Griffiths EK, Sanchez O, Mill P, Krawczyk C, Hojilla CV, Rubin E, Nau MM, Khokha R, Lipkowitz S, Hui CC, Penninger JM. Cbl-3-deficient mice exhibit normal epithelial development. Molecular and Cellular Biology. 23: 7708-18. PMID 14560016 DOI: 10.1128/Mcb.23.21.7708-7718.2003 |
0.311 |
|
| 2003 |
Magnifico A, Ettenberg S, Yang C, Mariano J, Tiwari S, Fang S, Lipkowitz S, Weissman AM. WW domain HECT E3s target Cbl RING finger E3s for proteasomal degradation. The Journal of Biological Chemistry. 278: 43169-77. PMID 12907674 DOI: 10.1074/Jbc.M308009200 |
0.422 |
|
| 2002 |
Szymkiewicz I, Kowanetz K, Soubeyran P, Dinarina A, Lipkowitz S, Dikic I. CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases Journal of Biological Chemistry. 277: 39666-39672. PMID 12177062 DOI: 10.1074/Jbc.M205535200 |
0.329 |
|
| 2002 |
Sattler M, Pride YB, Quinnan LR, Verma S, Malouf NA, Husson H, Salgia R, Lipkowitz S, Griffin JD. Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells Oncogene. 21: 1423-1433. PMID 11857085 DOI: 10.1038/Sj.Onc.1205202 |
0.344 |
|
| 2001 |
Ettenberg SA, Magnifico A, Cuello M, Nau MM, Rubinstein YR, Yarden Y, Weissman AM, Lipkowitz S. Cbl-b-dependent Coordinated Degradation of the Epidermal Growth Factor Receptor Signaling Complex Journal of Biological Chemistry. 276: 27677-27684. PMID 11375397 DOI: 10.1074/Jbc.M102641200 |
0.386 |
|
| 2000 |
Borinstein SC, Hyatt MA, Sykes VW, Straub RE, Lipkowitz S, Boulter J, Bogler O. SETA is a multifunctional adapter protein with three SH3 domains that binds Grb2, Cbl, and the novel SB1 proteins. Cellular Signalling. 12: 769-79. PMID 11152963 DOI: 10.1016/S0898-6568(00)00129-7 |
0.312 |
|
| 1999 |
Levkowitz G, Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I, Lavi S, Iwai K, Reiss Y, Ciechanover A, Lipkowitz S, Yarden Y. Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 Molecular Cell. 4: 1029-1040. PMID 10635327 DOI: 10.1016/S1097-2765(00)80231-2 |
0.406 |
|
| 1999 |
Ettenberg SA, Rubinstein YR, Banerjee P, Nau MM, Keane MM, Lipkowitz S. cbl-b inhibits EGF-receptor-induced apoptosis by enhancing ubiquitination and degradation of activated receptors Molecular Cell Biology Research Communications. 2: 111-118. PMID 10542134 |
0.353 |
|
| 1999 |
Keane MM, Ettenberg SA, Nau MM, Banerjee P, Cuello M, Penninger J, Lipkowitz S. cbl-3: A new mammalian cbl family protein Oncogene. 18: 3365-3375. PMID 10362357 DOI: 10.1038/Sj.Onc.1202753 |
0.419 |
|
| 1999 |
Ettenberg SA, Keane MM, Nau MM, Frankel M, Wang LM, Pierce JH, Lipkowitz S. cbl-b inhibits epidermal growth factor receptor signaling Oncogene. 18: 1855-1866. PMID 10086340 |
0.344 |
|
| 1997 |
Liu YC, Liu Y, Elly C, Yoshida H, Lipkowitz S, Altman A. Serine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3- binding motif Journal of Biological Chemistry. 272: 9979-9985. PMID 9092538 DOI: 10.1074/jbc.272.15.9979 |
0.341 |
|
| 1995 |
Keane MM, Rivero-Lezcano OM, Mitchell JA, Robbins KC, Lipkowitz S. Cloning and characterization of cbl-b: A SH3 binding protein with homology to the c-cbl proto-oncogene Oncogene. 10: 2367-2377. PMID 7784085 |
0.386 |
|
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