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Neil J. Ganem, Ph.D. - Publications

Affiliations: 
2006 Dartmouth College, Hanover, NH, United States 
Area:
Biochemistry, Cell Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vittoria MA, Quinton RJ, Ganem NJ. Whole-genome doubling in tissues and tumors. Trends in Genetics : Tig. PMID 37714734 DOI: 10.1016/j.tig.2023.08.004  0.47
2022 Darp R, Vittoria MA, Ganem NJ, Ceol CJ. Oncogenic BRAF induces whole-genome doubling through suppression of cytokinesis. Nature Communications. 13: 4109. PMID 35840569 DOI: 10.1038/s41467-022-31899-9  0.382
2021 Quinton RJ, DiDomizio A, Vittoria MA, Kotýnková K, Ticas CJ, Patel S, Koga Y, Vakhshoorzadeh J, Hermance N, Kuroda TS, Parulekar N, Taylor AM, Manning AL, Campbell JD, Ganem NJ. Publisher Correction: Whole-genome doubling confers unique genetic vulnerabilities on tumour cells. Nature. PMID 33976417 DOI: 10.1038/s41586-021-03591-3  0.653
2021 Quinton RJ, DiDomizio A, Vittoria MA, Kotýnková K, Ticas CJ, Patel S, Koga Y, Vakhshoorzadeh J, Hermance N, Kuroda TS, Parulekar N, Taylor AM, Manning AL, Campbell JD, Ganem NJ. Whole-genome doubling confers unique genetic vulnerabilities on tumour cells. Nature. PMID 33505027 DOI: 10.1038/s41586-020-03133-3  0.733
2020 Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, Liu J, Hu J, Quinton RJ, Ganem NJ, Liu P, et al. LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nature Cell Biology. PMID 32015438 DOI: 10.1038/S41556-020-0463-6  0.333
2019 Lim S, Hermance N, Mudianto T, Mustaly HM, Mauricio IPM, Vittoria MA, Quinton RJ, Howell BW, Cornils H, Manning AL, Ganem NJ. Identification of the kinase STK25 as an upstream activator of LATS signaling. Nature Communications. 10: 1547. PMID 30948712 DOI: 10.1038/S41467-019-09597-W  0.646
2019 Quinton RJ, Ganem NJ. CRISPR-Mediated Approaches to Regulate YAP/TAZ Levels. Methods in Molecular Biology (Clifton, N.J.). 1893: 203-214. PMID 30565136 DOI: 10.1007/978-1-4939-8910-2_16  0.34
2018 Bolgioni AF, Vittoria MA, Ganem NJ. Long-term Live-cell Imaging to Assess Cell Fate in Response to Paclitaxel. Journal of Visualized Experiments : Jove. PMID 29806834 DOI: 10.3791/57383  0.44
2018 Vittoria MA, Shenk EM, O'Rourke KP, Bolgioni AF, Lim S, Kacprzak V, Quinton RJ, Ganem NJ. A genome-wide miRNA screen identifies regulators of tetraploid cell proliferation. Molecular Biology of the Cell. mbcE18020141. PMID 29791254 DOI: 10.1091/Mbc.E18-02-0141  0.395
2017 Grant TJ, Mehta AK, Gupta A, Sharif AAD, Arora KS, Deshpande V, Ting DT, Bardeesy N, Ganem NJ, Hergovich A, Singh A. STK38L kinase ablation promotes loss of cell viability in a subset of KRAS-dependent pancreatic cancer cell lines. Oncotarget. 8: 78556-78572. PMID 29108249 DOI: 10.18632/Oncotarget.20833  0.462
2017 Henssen AG, Reed C, Jiang E, Garcia HD, von Stebut J, MacArthur IC, Hundsdoerfer P, Kim JH, de Stanchina E, Kuwahara Y, Hosoi H, Ganem NJ, Dela Cruz F, Kung AL, Schulte JH, et al. Therapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors. Science Translational Medicine. 9. PMID 29093183 DOI: 10.1126/Scitranslmed.Aam9078  0.399
2016 Lim S, Quinton RJ, Ganem NJ. Nuclear envelope rupture drives genome instability in cancer. Molecular Biology of the Cell. 27: 3210-3213. PMID 27799497 DOI: 10.1091/Mbc.E16-02-0098  0.423
2016 Shenk EM, Ganem NJ. Generation and Purification of Tetraploid Cells. Methods in Molecular Biology (Clifton, N.J.). 1413: 393-401. PMID 27193862 DOI: 10.1007/978-1-4939-3542-0_24  0.514
2016 Bolgioni AF, Ganem NJ. The interplay between centrosomes and the Hippo tumor suppressor pathway. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 24: 93-104. PMID 26582635 DOI: 10.1007/S10577-015-9502-8  0.516
2015 Russo A, Pacchierotti F, Cimini D, Ganem NJ, Genescà A, Natarajan AT, Pavanello S, Valle G, Degrassi F. Genomic instability: Crossing pathways at the origin of structural and numerical chromosome changes. Environmental and Molecular Mutagenesis. PMID 25784636 DOI: 10.1002/Em.21945  0.468
2015 Flynn RL, Cox KE, Jeitany M, Wakimoto H, Bryll AR, Ganem NJ, Bersani F, Pineda JR, Suvà ML, Benes CH, Haber DA, Boussin FD, Zou L. Alternative lengthening of telomeres renders cancer cells hypersensitive to ATR inhibitors. Science (New York, N.Y.). 347: 273-7. PMID 25593184 DOI: 10.1126/Science.1257216  0.486
2014 Lim S, Ganem NJ. Tetraploidy and tumor development. Oncotarget. 5: 10959-60. PMID 25526024 DOI: 10.18632/Oncotarget.2790  0.579
2014 Ganem NJ, Cornils H, Chiu SY, O'Rourke KP, Arnaud J, Yimlamai D, Théry M, Camargo FD, Pellman D. Cytokinesis failure triggers hippo tumor suppressor pathway activation. Cell. 158: 833-48. PMID 25126788 DOI: 10.1016/J.Cell.2014.06.029  0.48
2012 Ganem NJ, Pellman D. Linking abnormal mitosis to the acquisition of DNA damage. The Journal of Cell Biology. 199: 871-81. PMID 23229895 DOI: 10.1083/Jcb.201210040  0.444
2012 Crasta K, Ganem NJ, Dagher R, Lantermann AB, Ivanova EV, Pan Y, Nezi L, Protopopov A, Chowdhury D, Pellman D. DNA breaks and chromosome pulverization from errors in mitosis. Nature. 482: 53-8. PMID 22258507 DOI: 10.1038/Nature10802  0.402
2011 Ganem NJ, O'Rourke KP, Pellman D. Abstract 2941: Defining novel pathways that arrest genetically unstable tetraploid cells Cancer Research. 71: 2941-2941. DOI: 10.1158/1538-7445.Am2011-2941  0.476
2009 Rhodes J, Amsterdam A, Sanda T, Moreau LA, McKenna K, Heinrichs S, Ganem NJ, Ho KW, Neuberg DS, Johnston A, Ahn Y, Kutok JL, Hromas R, Wray J, Lee C, et al. Emi1 maintains genomic integrity during zebrafish embryogenesis and cooperates with p53 in tumor suppression. Molecular and Cellular Biology. 29: 5911-22. PMID 19704007 DOI: 10.1128/Mcb.00558-09  0.517
2009 Ganem NJ, Godinho SA, Pellman D. A mechanism linking extra centrosomes to chromosomal instability. Nature. 460: 278-82. PMID 19506557 DOI: 10.1038/Nature08136  0.575
2009 Godinho SA, Kwon M, Ganem NJ, Pellman D. Abstract C65: Mechanisms to maintain extra centrosomes in cancer cells Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-C65  0.517
2008 Kwon M, Godinho SA, Chandhok NS, Ganem NJ, Azioune A, Thery M, Pellman D. Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Genes & Development. 22: 2189-203. PMID 18662975 DOI: 10.1101/Gad.1700908  0.568
2007 Ganem NJ, Pellman D. Limiting the proliferation of polyploid cells. Cell. 131: 437-40. PMID 17981108 DOI: 10.1016/J.Cell.2007.10.024  0.522
2007 Manning AL, Ganem NJ, Bakhoum SF, Wagenbach M, Wordeman L, Compton DA. The kinesin-13 proteins Kif2a, Kif2b, and Kif2c/MCAK have distinct roles during mitosis in human cells. Molecular Biology of the Cell. 18: 2970-9. PMID 17538014 DOI: 10.1091/Mbc.E07-02-0110  0.674
2007 Ganem NJ, Storchova Z, Pellman D. Tetraploidy, aneuploidy and cancer. Current Opinion in Genetics & Development. 17: 157-62. PMID 17324569 DOI: 10.1016/J.Gde.2007.02.011  0.551
2006 Ganem NJ, Compton DA. Functional roles of poleward microtubule flux during mitosis. Cell Cycle (Georgetown, Tex.). 5: 481-5. PMID 16552178 DOI: 10.4161/Cc.5.5.2519  0.675
2005 Ganem NJ, Upton K, Compton DA. Efficient mitosis in human cells lacking poleward microtubule flux. Current Biology : Cb. 15: 1827-32. PMID 16243029 DOI: 10.1016/J.Cub.2005.08.065  0.694
2004 Ganem NJ, Compton DA. The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK. The Journal of Cell Biology. 166: 473-8. PMID 15302853 DOI: 10.1083/Jcb.200404012  0.68
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