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Igor Dikiy, Ph.D. - Publications

Affiliations: 
2009-2015 Biochemistry and Structural Biology Weill Cornell Medical College, New York, NY, United States 
 2015- Structural Biology CUNY Advanced Science Research Center 
Area:
Biochemistry, General Biophysics
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dikiy I, Swingle D, Toy K, Edupuganti UR, Rivera-Cancel G, Gardner KH. Diversity of function and higher-order structure within HWE sensor histidine kinases. The Journal of Biological Chemistry. 104934. PMID 37331599 DOI: 10.1016/j.jbc.2023.104934  0.507
2021 Xu X, Dikiy I, Evans MR, Marcelino LP, Gardner KH. Fragile protein folds: Sequence and environmental factors affecting the equilibrium of two interconverting, stably folded protein conformations. Magnetic Resonance (Gottingen, Germany). 2: 63-76. PMID 35603043 DOI: 10.5194/mr-2-63-2021  0.734
2019 Dikiy I, Gardner KH. Shining light on the alphaproteobacterial general stress response: Comment on: Fiebig et al., Mol Microbiol, 2019. Molecular Microbiology. PMID 31120626 DOI: 10.1111/Mmi.14311  0.512
2019 Dikiy I, Edupuganti UR, Abzalimov RR, Borbat PP, Srivastava M, Freed JH, Gardner KH. Insights into histidine kinase activation mechanisms from the monomeric blue light sensor EL346. Proceedings of the National Academy of Sciences of the United States of America. PMID 30808807 DOI: 10.1073/Pnas.1813586116  0.741
2019 Dikiy I, Clark LD, Gardner KH, Rosenbaum DM. Isotopic Labeling of Eukaryotic Membrane Proteins for NMR Studies of Interactions and Dynamics. Methods in Enzymology. 614: 37-65. PMID 30611431 DOI: 10.1016/Bs.Mie.2018.08.030  0.555
2018 Clark L, Dikiy I, Rosenbaum DM, Gardner KH. On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies. Journal of Biomolecular Nmr. PMID 30121871 DOI: 10.1007/S10858-018-0204-3  0.551
2017 Clark LD, Dikiy I, Chapman K, Rödström KEJ, Aramini J, LeVine MV, Khelashvili G, Rasmussen SGF, Gardner KH, Rosenbaum DM. Ligand modulation of sidechain dynamics in a wild-type human GPCR. Elife. 6. PMID 28984574 DOI: 10.1016/J.Bpj.2017.11.1330  0.535
2017 Clark LD, Dikiy I, Chapman K, Rödström KE, Aramini J, LeVine MV, Khelashvili G, Rasmussen SG, Gardner KH, Rosenbaum DM. Author response: Ligand modulation of sidechain dynamics in a wild-type human GPCR Elife. DOI: 10.7554/Elife.28505.028  0.465
2016 Kim DM, Dikiy I, Upadhyay V, Posson DJ, Eliezer D, Nimigean CM. Conformational heterogeneity in closed and open states of the KcsA potassium channel in lipid bicelles. The Journal of General Physiology. PMID 27432996 DOI: 10.1085/Jgp.201611602  0.541
2016 Dikiy I, Fauvet B, Jovičić A, Mahul-Mellier AL, Desobry C, El-Turk F, Gitler AD, Lashuel HA, Eliezer D. Semisynthetic and in vitro phosphorylation of alpha-synuclein at Y39 promotes functional partly-helical membrane-bound states resembling those induced by PD mutations. Acs Chemical Biology. PMID 27356045 DOI: 10.1021/Acschembio.6B00539  0.594
2016 Kim DM, Dikiy I, Upadhyay V, Posson D, Eliezer D, Nimigean C. Conformational Dynamics of the Closed State of KcsA in Lipid Bicelles Biophysical Journal. 110: 291a-292a. DOI: 10.1016/J.Bpj.2015.11.1576  0.572
2015 Iaea DB, Dikiy I, Kiburu I, Eliezer D, Maxfield FR. STARD4 Membrane Interactions and Sterol Binding. Biochemistry. 54: 4623-36. PMID 26168008 DOI: 10.1021/Acs.Biochem.5B00618  0.576
2014 Khalaf O, Fauvet B, Oueslati A, Dikiy I, Mahul-Mellier AL, Ruggeri FS, Mbefo MK, Vercruysse F, Dietler G, Lee SJ, Eliezer D, Lashuel HA. The H50Q mutation enhances α-synuclein aggregation, secretion, and toxicity. The Journal of Biological Chemistry. 289: 21856-76. PMID 24936070 DOI: 10.1074/Jbc.M114.553297  0.517
2014 Fares MB, Ait-Bouziad N, Dikiy I, Mbefo MK, Jovičić A, Kiely A, Holton JL, Lee SJ, Gitler AD, Eliezer D, Lashuel HA. The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells. Human Molecular Genetics. 23: 4491-509. PMID 24728187 DOI: 10.1093/Hmg/Ddu165  0.523
2014 Mahul-Mellier AL, Fauvet B, Gysbers A, Dikiy I, Oueslati A, Georgeon S, Lamontanara AJ, Bisquertt A, Eliezer D, Masliah E, Halliday G, Hantschel O, Lashuel HA. c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's disease. Human Molecular Genetics. 23: 2858-79. PMID 24412932 DOI: 10.1093/Hmg/Ddt674  0.539
2014 Dikiy I, Eliezer D. N-terminal acetylation stabilizes N-terminal helicity in lipid- and micelle-bound α-synuclein and increases its affinity for physiological membranes. The Journal of Biological Chemistry. 289: 3652-65. PMID 24338013 DOI: 10.1074/Jbc.M113.512459  0.552
2014 Kim DM, Dikiy I, Posson D, Eliezer D, Nimigean CM. Proton-Dependent Conformational Dynamics in KcsA Biophysical Journal. 106: 154a. DOI: 10.1016/J.Bpj.2013.11.885  0.594
2013 Dikiy I, Ramlall TF, Eliezer D. ¹H, ¹³C, and ¹⁵N backbone resonance assignments of the L124D mutant of StAR-related lipid transfer domain protein 4 (StARD4). Biomolecular Nmr Assignments. 7: 245-8. PMID 22918595 DOI: 10.1007/S12104-012-9419-5  0.56
2013 Kim D, Posson D, Thompson A, McCoy J, Dikiy I, Eliezer D, Nimigean C. Proton Binding and Conformational Dynamics in KcsA Biophysical Journal. 104: 542a. DOI: 10.1016/J.Bpj.2012.11.3004  0.584
2012 Fauvet B, Fares MB, Samuel F, Dikiy I, Tandon A, Eliezer D, Lashuel HA. Characterization of semisynthetic and naturally Nα-acetylated α-synuclein in vitro and in intact cells: implications for aggregation and cellular properties of α-synuclein. The Journal of Biological Chemistry. 287: 28243-62. PMID 22718772 DOI: 10.1074/Jbc.M112.383711  0.565
2012 Hejjaoui M, Butterfield S, Fauvet B, Vercruysse F, Cui J, Dikiy I, Prudent M, Olschewski D, Zhang Y, Eliezer D, Lashuel HA. Elucidating the role of C-terminal post-translational modifications using protein semisynthesis strategies: α-synuclein phosphorylation at tyrosine 125. Journal of the American Chemical Society. 134: 5196-210. PMID 22339654 DOI: 10.1021/Ja210866J  0.582
2012 Dikiy I, Eliezer D. Folding and misfolding of alpha-synuclein on membranes. Biochimica Et Biophysica Acta. 1818: 1013-8. PMID 21945884 DOI: 10.1016/J.Bbamem.2011.09.008  0.559
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