Dario DiFrancesco - Publications

Affiliations: 
Università degli Studi di Milano, Italy, Milano, Lombardia, Italy 
Area:
Ih channels

158 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Piantoni C, Paina M, Molla D, Liu S, Bertoli G, Jiang H, Wang Y, Wang Y, Wang Y, DiFrancesco D, Barbuti A, Bucchi A, Baruscotti M. Chinese natural compound decreases pacemaking of rabbit cardiac sinoatrial cells by targeting second messenger regulation of f-channels. Elife. 11. PMID 35315774 DOI: 10.7554/eLife.75119  0.369
2021 Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, ... ... DiFrancesco D, et al. Gating movements and ion permeation in HCN4 pacemaker channels. Molecular Cell. PMID 34166608 DOI: 10.1016/j.molcel.2021.05.033  0.355
2019 DiFrancesco D. A Brief History of Pacemaking. Frontiers in Physiology. 10: 1599. PMID 32038284 DOI: 10.3389/fphys.2019.01599  0.427
2019 DiFrancesco JC, Castellotti B, Milanesi R, Ragona F, Freri E, Canafoglia L, Franceschetti S, Ferrarese C, Magri S, Taroni F, Costa C, Labate A, Gambardella A, Solazzi R, Binda A, ... ... DiFrancesco D, et al. HCN ion channels and accessory proteins in epilepsy: genetic analysis of a large cohort of patients and review of the literature. Epilepsy Research. 153: 49-58. PMID 30986657 DOI: 10.1016/j.eplepsyres.2019.04.004  0.418
2018 Marini C, Porro A, Rastetter A, Dalle C, Rivolta I, Bauer D, Oegema R, Nava C, Parrini E, Mei D, Mercer C, Dhamija R, Chambers C, Coubes C, Thévenon J, ... ... DiFrancesco D, et al. HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond. Brain : a Journal of Neurology. 141: 3160-3178. PMID 30351409 DOI: 10.1093/Brain/Awy263  0.36
2018 Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A. A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels. Elife. 7. PMID 29923826 DOI: 10.7554/Elife.35753  0.357
2018 Saponaro A, Cantini F, Porro A, Bucchi A, DiFrancesco D, Maione V, Donadoni C, Introini B, Mesirca P, Mangoni ME, Thiel G, Banci L, Santoro B, Moroni A. Author response: A synthetic peptide that prevents cAMP regulation in mammalian hyperpolarization-activated cyclic nucleotide-gated (HCN) channels Elife. DOI: 10.7554/Elife.35753.022  0.399
2017 Baruscotti M, Bucchi A, Milanesi R, Paina M, Barbuti A, Gnecchi-Ruscone T, Bianco E, Vitali-Serdoz L, Cappato R, DiFrancesco D. A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia. European Heart Journal. 38: 280-288. PMID 28182231 DOI: 10.1093/eurheartj/ehv582  0.418
2017 Paina M, Piantoni C, Carnevali L, Frosio A, Bucchi A, Barbuti A, Sheng L, Yanyan W, Wang Y, DiFrancesco D, Baruscotti M. A Traditional Chinese Medicine Drug (TMYX) Controls Heart Rate by Modulation of the Pacemaker (F) Channels Biophysical Journal. 112: 412a. DOI: 10.1016/j.bpj.2016.11.2565  0.359
2017 Piantoni C, Gualdoni A, Bazzini C, Milanesi R, Adelfio M, Bucchi A, Barbuti A, Pecchiari M, Baruscotti M, DiFrancesco D. HCN3 Channel Expression in Human Leukocytes Biophysical Journal. 112: 415a. DOI: 10.1016/j.bpj.2016.11.2224  0.369
2016 Biel S, Aquila M, Hertel B, Berthold A, Neumann T, DiFrancesco D, Moroni A, Thiel G, Kauferstein S. Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function. Pflugers Archiv : European Journal of Physiology. PMID 27553229 DOI: 10.1007/S00424-016-1870-1  0.468
2016 Baruscotti M, Bianco E, Bucchi A, DiFrancesco D. Current understanding of the pathophysiological mechanisms responsible for inappropriate sinus tachycardia: role of the If "funny" current. Journal of Interventional Cardiac Electrophysiology : An International Journal of Arrhythmias and Pacing. PMID 26781742 DOI: 10.1007/s10840-015-0097-y  0.334
2016 Meraviglia V, Wen J, Piacentini L, Campostrini G, Wang C, Florio MC, Azzimato V, Fassina L, Langes M, Wong J, Miragoli M, Gaetano C, Pompilio G, Barbuti A, DiFrancesco D, et al. Higher cardiogenic potential of iPSCs derived from cardiac versus skin stromal cells. Frontiers in Bioscience (Landmark Edition). 21: 719-43. PMID 26709802 DOI: 10.2741/4417  0.328
2016 Sag C, Ward A, Crocini C, Watkins A, Hayer S, Wang Y, Rex N, Wagner S, De Franceschi L, Vinchi F, Cimino J, Petrillo S, Silengo L, Altruda F, Maier LS, ... ... DiFrancesco D, et al. Late Breaking Science502Hemopexin counteracts systolic dysfunction induced by heme overload503Inhibition of NF-kappa B suppressed inflammation induced by acute shear stress in endothelial cells: Implications for vein graft failure504Optical treatment of cardiac arrhythmias505Tachypacing-induced heart failure: a metabolomic investigation506Characterization of early left ventricle dysfunction in a relevant experimental model for human rheumatoid arthritis507Circadian rhythm in heart rate is due to an intrinsic circadian clock in the sinus node Cardiovascular Research. 111: S90-S91. DOI: 10.1093/Cvr/Cvw142  0.314
2015 DiFrancesco D. HCN4, Sinus Bradycardia and Atrial Fibrillation. Arrhythmia & Electrophysiology Review. 4: 9-13. PMID 26835093 DOI: 10.15420/aer.2015.4.1.9  0.465
2015 Ravagli E, Bucchi A, Bartolucci C, Paina M, Baruscotti M, DiFrancesco D, Severi S. Cell-specific Dynamic Clamp analysis of the role of funny If current in cardiac pacemaking. Progress in Biophysics and Molecular Biology. PMID 26718599 DOI: 10.1016/j.pbiomolbio.2015.12.004  0.405
2015 DiFrancesco JC, DiFrancesco D. Dysfunctional HCN ion channels in neurological diseases. Frontiers in Cellular Neuroscience. 6: 174. PMID 25805968 DOI: 10.3389/fncel.2015.00071  0.493
2015 Meraviglia V, Wen J, Piacentini L, Campostrini G, Wang C, Florio M, Azzimato V, Fassina L, Langes M, Wong J, Miragoli M, Gaetano C, Pompilio G, Barbuti A, DiFrancesco D, et al. High cardiac differentiation properties are evident in induced pluripotent stem cells obtained from atrial mesenchymal cells Vascular Pharmacology. 75: 68. DOI: 10.1016/J.Vph.2015.11.069  0.303
2014 D'Souza A, Bucchi A, Johnsen AB, Logantha SJ, Monfredi O, Yanni J, Prehar S, Hart G, Cartwright E, Wisloff U, Dobryznski H, DiFrancesco D, Morris GM, Boyett MR. Exercise training reduces resting heart rate via downregulation of the funny channel HCN4. Nature Communications. 5: 3775. PMID 24825544 DOI: 10.1038/ncomms4775  0.36
2014 Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Schroeder I, Simmons K, Aquila M, DiFrancesco D, Bolognesi M, Schwede F, Kashin D, Fishwick CW, Johnson AP, Thiel G, et al. Cyclic dinucleotides bind the C-linker of HCN4 to control channel cAMP responsiveness. Nature Chemical Biology. 10: 457-62. PMID 24776929 DOI: 10.1038/Nchembio.1521  0.401
2014 Barbuti A, DiFrancesco D. The 'funny' side of sepsis. The Journal of Physiology. 592: 1171. PMID 24634015 DOI: 10.1113/jphysiol.2014.271171  0.446
2014 Ravagli E, Bucchi A, Bartolucci C, Baruscotti M, DiFrancesco D, Severi S. How “Funny” is the Cardiac Pacemaking? a Quantitative Analysis Based on Dynamic Clamp Recordings Biophysical Journal. 106: 722a. DOI: 10.1016/j.bpj.2013.11.3987  0.369
2014 Moroni A, Lolicato M, Bucchi A, Arrigoni C, Zucca S, Nardini M, Simmons K, Aquila M, Schwede F, Thiel G, Bolognesi M, DiFrancesco D. Discovery and Characterization of a Distinct Cyclic Nucleotide Binding Pocket in HCN Channels Biophysical Journal. 106: 627a. DOI: 10.1016/J.Bpj.2013.11.3470  0.424
2013 Difrancesco D, Nawathe PA, Robinson RB. Multifactorial impact of channel beta-subunit gene mutation on automaticity. Journal of Cardiovascular Electrophysiology. 24: E26-7. PMID 24015862 DOI: 10.1111/Jce.12235  0.319
2013 Nawathe PA, Kryukova Y, Oren RV, Milanesi R, Clancy CE, Lu JT, Moss AJ, Difrancesco D, Robinson RB. An LQTS6 MiRP1 mutation suppresses pacemaker current and is associated with sinus bradycardia. Journal of Cardiovascular Electrophysiology. 24: 1021-7. PMID 23631727 DOI: 10.1111/Jce.12163  0.437
2013 DiFrancesco D. Funny channel gene mutations associated with arrhythmias. The Journal of Physiology. 591: 4117-24. PMID 23507880 DOI: 10.1113/jphysiol.2013.253765  0.475
2013 Bucchi A, Baruscotti M, Nardini M, Barbuti A, Micheloni S, Bolognesi M, DiFrancesco D. Identification of the molecular site of ivabradine binding to HCN4 channels. Plos One. 8: e53132. PMID 23308150 DOI: 10.1371/journal.pone.0053132  0.454
2012 Vecellio M, Meraviglia V, Nanni S, Barbuti A, Scavone A, DiFrancesco D, Farsetti A, Pompilio G, Colombo GI, Capogrossi MC, Gaetano C, Rossini A. In vitro epigenetic reprogramming of human cardiac mesenchymal stromal cells into functionally competent cardiovascular precursors. Plos One. 7: e51694. PMID 23284745 DOI: 10.1371/journal.pone.0051694  0.36
2012 Bucchi A, Barbuti A, Difrancesco D, Baruscotti M. Funny Current and Cardiac Rhythm: Insights from HCN Knockout and Transgenic Mouse Models. Frontiers in Physiology. 3: 240. PMID 22783204 DOI: 10.3389/fphys.2012.00240  0.458
2012 Severi S, Fantini M, Charawi LA, DiFrancesco D. An updated computational model of rabbit sinoatrial action potential to investigate the mechanisms of heart rate modulation. The Journal of Physiology. 590: 4483-99. PMID 22711956 DOI: 10.1113/jphysiol.2012.229435  0.43
2012 Barbuti A, Scavone A, Mazzocchi N, Terragni B, Baruscotti M, Difrancesco D. A caveolin-binding domain in the HCN4 channels mediates functional interaction with caveolin proteins. Journal of Molecular and Cellular Cardiology. 53: 187-95. PMID 22659290 DOI: 10.1016/j.yjmcc.2012.05.013  0.466
2012 DiFrancesco D, Noble D. Rebuttal: "The funny current in the context of the coupled clock pacemaker cell system". Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 457-8. PMID 21925135 DOI: 10.1016/j.hrthm.2011.09.023  0.381
2012 DiFrancesco D, Noble D. The funny current has a major pacemaking role in the sinus node. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 299-301. PMID 21925134 DOI: 10.1016/j.hrthm.2011.09.021  0.474
2012 Severi S, Fantini M, Ravagli E, Charawi L, DiFrancesco D. A Validated Computational Model of Cardiac Pacemaking: Mechanisms of Physiological and Pharmacological Rate Modulation Biophysical Journal. 102: 672a. DOI: 10.1016/j.bpj.2011.11.3660  0.399
2011 DiFrancesco JC, Barbuti A, Milanesi R, Coco S, Bucchi A, Bottelli G, Ferrarese C, Franceschetti S, Terragni B, Baruscotti M, DiFrancesco D. Recessive loss-of-function mutation in the pacemaker HCN2 channel causing increased neuronal excitability in a patient with idiopathic generalized epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17327-37. PMID 22131395 DOI: 10.1523/JNEUROSCI.3727-11.2011  0.421
2011 Avitabile D, Crespi A, Brioschi C, Parente V, Toietta G, Devanna P, Baruscotti M, Truffa S, Scavone A, Rusconi F, Biondi A, D'Alessandra Y, Vigna E, Difrancesco D, Pesce M, et al. Human cord blood CD34+ progenitor cells acquire functional cardiac properties through a cell fusion process. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1875-84. PMID 21357510 DOI: 10.1152/ajpheart.00523.2010  0.336
2011 Baruscotti M, Bucchi A, Viscomi C, Mandelli G, Consalez G, Gnecchi-Rusconi T, Montano N, Casali KR, Micheloni S, Barbuti A, DiFrancesco D. Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4. Proceedings of the National Academy of Sciences of the United States of America. 108: 1705-10. PMID 21220308 DOI: 10.1073/pnas.1010122108  0.489
2011 Rossini A, Frati C, Lagrasta C, Graiani G, Scopece A, Cavalli S, Musso E, Baccarin M, Di Segni M, Fagnoni F, Germani A, Quaini E, Mayr M, Xu Q, Barbuti A, ... DiFrancesco D, et al. Human cardiac and bone marrow stromal cells exhibit distinctive properties related to their origin. Cardiovascular Research. 89: 650-60. PMID 20833652 DOI: 10.1093/cvr/cvq290  0.331
2010 Baruscotti M, Bottelli G, Milanesi R, DiFrancesco JC, DiFrancesco D. HCN-related channelopathies. PflüGers Archiv : European Journal of Physiology. 460: 405-15. PMID 20213494 DOI: 10.1007/s00424-010-0810-8  0.495
2010 DiFrancesco D. The role of the funny current in pacemaker activity. Circulation Research. 106: 434-46. PMID 20167941 DOI: 10.1161/CIRCRESAHA.109.208041  0.506
2010 DiFrancesco D. Funny channel-based pacemaking. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 276-9. PMID 20022815 DOI: 10.1016/j.hrthm.2009.10.030  0.41
2010 Barbuti A, Galvez BG, Crespi A, Scavone A, Baruscotti M, Brioschi C, Cossu G, DiFrancesco D. Mesoangioblasts from ventricular vessels can differentiate in vitro into cardiac myocytes with sinoatrial-like properties. Journal of Molecular and Cellular Cardiology. 48: 415-23. PMID 19837079 DOI: 10.1016/j.yjmcc.2009.10.006  0.449
2010 DiFrancesco D. Considerations on the size of currents required for pacemaking Journal of Molecular and Cellular Cardiology. 48: 802-803. DOI: 10.1016/j.yjmcc.2009.11.022  0.305
2009 Brioschi C, Micheloni S, Tellez JO, Pisoni G, Longhi R, Moroni P, Billeter R, Barbuti A, Dobrzynski H, Boyett MR, DiFrancesco D, Baruscotti M. Distribution of the pacemaker HCN4 channel mRNA and protein in the rabbit sinoatrial node. Journal of Molecular and Cellular Cardiology. 47: 221-7. PMID 19394343 DOI: 10.1016/j.yjmcc.2009.04.009  0.444
2009 Lakatta EG, DiFrancesco D. What keeps us ticking: a funny current, a calcium clock, or both? Journal of Molecular and Cellular Cardiology. 47: 157-70. PMID 19361514 DOI: 10.1016/j.yjmcc.2009.03.022  0.485
2009 Chandler NJ, Greener ID, Tellez JO, Inada S, Musa H, Molenaar P, Difrancesco D, Baruscotti M, Longhi R, Anderson RH, Billeter R, Sharma V, Sigg DC, Boyett MR, Dobrzynski H. Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker. Circulation. 119: 1562-75. PMID 19289639 DOI: 10.1161/Circulationaha.108.804369  0.369
2009 Barbuti A, Crespi A, Capilupo D, Mazzocchi N, Baruscotti M, DiFrancesco D. Molecular composition and functional properties of f-channels in murine embryonic stem cell-derived pacemaker cells. Journal of Molecular and Cellular Cardiology. 46: 343-51. PMID 19135060 DOI: 10.1016/j.yjmcc.2008.12.001  0.448
2008 Galvez BG, Sampaolesi M, Barbuti A, Crespi A, Covarello D, Brunelli S, Dellavalle A, Crippa S, Balconi G, Cuccovillo I, Molla F, Staszewsky L, Latini R, Difrancesco D, Cossu G. Cardiac mesoangioblasts are committed, self-renewable progenitors, associated with small vessels of juvenile mouse ventricle. Cell Death and Differentiation. 15: 1417-28. PMID 18497758 DOI: 10.1038/cdd.2008.75  0.356
2008 Barbuti A, DiFrancesco D. Control of cardiac rate by "funny" channels in health and disease. Annals of the New York Academy of Sciences. 1123: 213-23. PMID 18375593 DOI: 10.1196/annals.1420.024  0.509
2007 DiFrancesco D, Borer JS. The funny current: cellular basis for the control of heart rate. Drugs. 67: 15-24. PMID 17999560 DOI: 10.2165/00003495-200767002-00003  0.488
2007 Bucchi A, Baruscotti M, Robinson RB, DiFrancesco D. Modulation of rate by autonomic agonists in SAN cells involves changes in diastolic depolarization and the pacemaker current. Journal of Molecular and Cellular Cardiology. 43: 39-48. PMID 17543331 DOI: 10.1016/J.Yjmcc.2007.04.017  0.44
2007 Barbuti A, Baruscotti M, DiFrancesco D. The pacemaker current: from basics to the clinics. Journal of Cardiovascular Electrophysiology. 18: 342-7. PMID 17284289 DOI: 10.1111/j.1540-8167.2006.00736.x  0.395
2007 Bucchi A, Barbuti A, Baruscotti M, DiFrancesco D. Heart rate reduction via selective 'funny' channel blockers. Current Opinion in Pharmacology. 7: 208-13. PMID 17267284 DOI: 10.1016/j.coph.2006.09.005  0.46
2007 Barbuti A, Terragni B, Brioschi C, DiFrancesco D. Localization of f-channels to caveolae mediates specific beta2-adrenergic receptor modulation of rate in sinoatrial myocytes. Journal of Molecular and Cellular Cardiology. 42: 71-8. PMID 17070839 DOI: 10.1016/j.yjmcc.2006.09.018  0.35
2007 Baruscotti M, Bucchi A, Robinson RB, DiFrancesco D. Autonomic rate modulation in san cells involves changes in diastolic depolarization and the i(f) current Journal of Molecular and Cellular Cardiology. 42: S14. DOI: 10.1016/J.Yjmcc.2007.03.040  0.393
2006 DiFrancesco D. Funny channels in the control of cardiac rhythm and mode of action of selective blockers. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 53: 399-406. PMID 16638640 DOI: 10.1016/j.phrs.2006.03.006  0.536
2006 Bucchi A, Tognati A, Milanesi R, Baruscotti M, DiFrancesco D. Properties of ivabradine-induced block of HCN1 and HCN4 pacemaker channels. The Journal of Physiology. 572: 335-46. PMID 16484306 DOI: 10.1113/jphysiol.2005.100776  0.496
2006 Milanesi R, Baruscotti M, Gnecchi-Ruscone T, DiFrancesco D. Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel. The New England Journal of Medicine. 354: 151-7. PMID 16407510 DOI: 10.1056/NEJMoa052475  0.483
2006 DiFrancesco D. Serious workings of the funny current. Progress in Biophysics and Molecular Biology. 90: 13-25. PMID 15975637 DOI: 10.1016/j.pbiomolbio.2005.05.001  0.515
2005 DiFrancesco D. Letter regarding article by Michels et al, "Single-channel properties support a potential contribution of hyperpolarization-activated cyclic nucleotide-gated channels and If to cardiac arrhythmias". Circulation. 112: e72; author reply e7. PMID 16061749 DOI: 10.1161/CIRCULATIONAHA.105.541367  0.496
2005 DiFrancesco D. Cardiac pacemaker I(f) current and its inhibition by heart rate-reducing agents. Current Medical Research and Opinion. 21: 1115-22. PMID 16004681 DOI: 10.1185/030079905X50543  0.504
2005 Baruscotti M, Bucchi A, Difrancesco D. Physiology and pharmacology of the cardiac pacemaker ("funny") current. Pharmacology & Therapeutics. 107: 59-79. PMID 15963351 DOI: 10.1016/j.pharmthera.2005.01.005  0.522
2004 DiFrancesco D, Camm JA. Heart rate lowering by specific and selective I(f) current inhibition with ivabradine: a new therapeutic perspective in cardiovascular disease. Drugs. 64: 1757-65. PMID 15301560 DOI: 10.2165/00003495-200464160-00003  0.415
2004 Gravante B, Barbuti A, Milanesi R, Zappi I, Viscomi C, DiFrancesco D. Interaction of the pacemaker channel HCN1 with filamin A. The Journal of Biological Chemistry. 279: 43847-53. PMID 15292205 DOI: 10.1074/jbc.M401598200  0.437
2004 Baruscotti M, Difrancesco D. Pacemaker channels. Annals of the New York Academy of Sciences. 1015: 111-21. PMID 15201153 DOI: 10.1196/annals.1302.009  0.401
2004 Gazzarrini S, Kang M, Van Etten JL, Tayefeh S, Kast SM, DiFrancesco D, Thiel G, Moroni A. Long distance interactions within the potassium channel pore are revealed by molecular diversity of viral proteins. The Journal of Biological Chemistry. 279: 28443-9. PMID 15105432 DOI: 10.1074/Jbc.M401184200  0.375
2004 Barbuti A, Gravante B, Riolfo M, Milanesi R, Terragni B, DiFrancesco D. Localization of pacemaker channels in lipid rafts regulates channel kinetics. Circulation Research. 94: 1325-31. PMID 15073040 DOI: 10.1161/01.RES.0000127621.54132.AE  0.422
2004 Kang M, Moroni A, Gazzarrini S, DiFrancesco D, Thiel G, Severino M, Van Etten JL. Small potassium ion channel proteins encoded by chlorella viruses. Proceedings of the National Academy of Sciences of the United States of America. 101: 5318-24. PMID 14762169 DOI: 10.1073/Pnas.0307824100  0.393
2003 Robinson RB, Baruscotti M, DiFrancesco D. Autonomic modulation of heart rate: pitfalls of nonselective channel blockade. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2865; author reply . PMID 14613917 DOI: 10.1152/ajpheart.00545.2003  0.382
2003 Gazzarrini S, Severino M, Lombardi M, Morandi M, DiFrancesco D, Van Etten JL, Thiel G, Moroni A. The viral potassium channel Kcv: structural and functional features. Febs Letters. 552: 12-6. PMID 12972145 DOI: 10.1016/S0014-5793(03)00777-4  0.408
2003 Bucchi A, Baruscotti M, Robinson RB, DiFrancesco D. I(f)-dependent modulation of pacemaker rate mediated by cAMP in the presence of ryanodine in rabbit sino-atrial node cells. Journal of Molecular and Cellular Cardiology. 35: 905-13. PMID 12878477 DOI: 10.1016/S0022-2828(03)00150-0  0.422
2003 Altomare C, Terragni B, Brioschi C, Milanesi R, Pagliuca C, Viscomi C, Moroni A, Baruscotti M, DiFrancesco D. Heteromeric HCN1-HCN4 channels: a comparison with native pacemaker channels from the rabbit sinoatrial node. The Journal of Physiology. 549: 347-59. PMID 12702747 DOI: 10.1113/jphysiol.2002.027698  0.502
2003 DiFrancesco D. If inhibition: A novel mechanism of action European Heart Journal, Supplement. 5: G19-G25. DOI: 10.1016/S1520-765X(03)90004-6  0.429
2002 Moroni A, Viscomi C, Sangiorgio V, Pagliuca C, Meckel T, Horvath F, Gazzarrini S, Valbuzzi P, Van Etten JL, DiFrancesco D, Thiel G. The short N-terminus is required for functional expression of the virus-encoded miniature K(+) channel Kcv. Febs Letters. 530: 65-9. PMID 12387867 DOI: 10.1016/S0014-5793(02)03397-5  0.385
2002 Qu J, Altomare C, Bucchi A, DiFrancesco D, Robinson RB. Functional comparison of HCN isoforms expressed in ventricular and HEK 293 cells. PflüGers Archiv : European Journal of Physiology. 444: 597-601. PMID 12194012 DOI: 10.1007/S00424-002-0860-7  0.501
2002 Demontis GC, Moroni A, Gravante B, Altomare C, Longoni B, Cervetto L, DiFrancesco D. Functional characterisation and subcellular localisation of HCN1 channels in rabbit retinal rod photoreceptors. The Journal of Physiology. 542: 89-97. PMID 12096053 DOI: 10.1113/jphysiol.2002.017640  0.483
2002 Bucchi A, Baruscotti M, DiFrancesco D. Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine. The Journal of General Physiology. 120: 1-13. PMID 12084770 DOI: 10.1085/jgp.20028593  0.528
2002 Gazzarrini S, Etten JL, DiFrancesco D, Thiel G, Moroni A. Voltage-dependence of virus-encoded miniature K+ channel Kcv. The Journal of Membrane Biology. 187: 15-25. PMID 12029374 DOI: 10.1007/S00232-001-0147-5  0.503
2002 DiFrancesco D, Robinson RB. beta-modulation of pacemaker rate: novel mechanism or novel mechanics of an old one? Circulation Research. 90: E69-9. PMID 11934845 DOI: 10.1161/01.Res.0000014803.05780.E7  0.314
2002 Accili EA, Proenza C, Baruscotti M, DiFrancesco D. From funny current to HCN channels: 20 years of excitation. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 17: 32-7. PMID 11821534 DOI: 10.1152/Physiologyonline.2002.17.1.32  0.508
2001 Protas L, DiFrancesco D, Robinson RB. L-type but not T-type calcium current changes during postnatal development in rabbit sinoatrial node. American Journal of Physiology. Heart and Circulatory Physiology. 281: H1252-9. PMID 11514294 DOI: 10.1152/Ajpheart.2001.281.3.H1252  0.38
2001 Baruscotti M, DiFrancesco D, Robinson RB. Single-channel properties of the sinoatrial node Na+ current in the newborn rabbit. PflüGers Archiv : European Journal of Physiology. 442: 192-6. PMID 11417213 DOI: 10.1007/S004240100527  0.523
2001 Viscomi C, Altomare C, Bucchi A, Camatini E, Baruscotti M, Moroni A, DiFrancesco D. C terminus-mediated control of voltage and cAMP gating of hyperpolarization-activated cyclic nucleotide-gated channels. The Journal of Biological Chemistry. 276: 29930-4. PMID 11397812 DOI: 10.1074/jbc.M103971200  0.419
2001 Altomare C, Bucchi A, Camatini E, Baruscotti M, Viscomi C, Moroni A, DiFrancesco D. Integrated allosteric model of voltage gating of HCN channels. The Journal of General Physiology. 117: 519-32. PMID 11382803 DOI: 10.1085/jgp.117.6.519  0.482
2001 Moroni A, Gorza L, Beltrame M, Gravante B, Vaccari T, Bianchi ME, Altomare C, Longhi R, Heurteaux C, Vitadello M, Malgaroli A, DiFrancesco D. Hyperpolarization-activated cyclic nucleotide-gated channel 1 is a molecular determinant of the cardiac pacemaker current I(f). The Journal of Biological Chemistry. 276: 29233-41. PMID 11328811 DOI: 10.1074/Jbc.M100830200  0.53
2001 DiFrancesco D, Moroni A, Baruscotti M, Accili EA. CHAPTER 18 – Cardiac Pacemaker Currents Journal of Biological Chemistry. 276: 357-372. DOI: 10.1016/B978-012656975-9/50020-1  0.461
2000 Baruscotti M, DiFrancesco D, Robinson RB. Na(+) current contribution to the diastolic depolarization in newborn rabbit SA node cells. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2303-9. PMID 11045966 DOI: 10.1152/Ajpheart.2000.279.5.H2303  0.455
2000 Altomare C, Barbuti A, Viscomi C, Baruscotti M, DiFrancesco D. Effects of dronedarone on acetylcholine-activated current in rabbit SAN cells. British Journal of Pharmacology. 130: 1315-20. PMID 10903971 DOI: 10.1038/sj.bjp.0703446  0.465
2000 Moroni A, Barbuti A, Altomare C, Viscomi C, Morgan J, Baruscotti M, DiFrancesco D. Kinetic and ionic properties of the human HCN2 pacemaker channel. PflüGers Archiv : European Journal of Physiology. 439: 618-26. PMID 10764222 DOI: 10.1007/s004240050985  0.535
2000 Moroni A, Gazzarrini S, Cerana R, Colombo R, Sutter JU, DiFrancesco D, Gradmann D, Thiel G. Mutation in pore domain uncovers cation- and voltage-sensitive recovery from inactivation in KAT1 channel. Biophysical Journal. 78: 1862-71. PMID 10733966 DOI: 10.1016/S0006-3495(00)76735-X  0.462
2000 Plugge B, Gazzarrini S, Nelson M, Cerana R, Van Etten JL, Derst C, DiFrancesco D, Moroni A, Thiel G. A potassium channel protein encoded by chlorella virus PBCV-1. Science (New York, N.Y.). 287: 1641-4. PMID 10698737 DOI: 10.1126/Science.287.5458.1641  0.382
1999 Barbuti A, Baruscotti M, Altomare C, Moroni A, DiFrancesco D. Action of internal pronase on the f-channel kinetics in the rabbit SA node. The Journal of Physiology. 520: 737-44. PMID 10545140 DOI: 10.1111/j.1469-7793.1999.00737.x  0.519
1999 Vaccari T, Moroni A, Rocchi M, Gorza L, Bianchi ME, Beltrame M, DiFrancesco D. The human gene coding for HCN2, a pacemaker channel of the heart. Biochimica Et Biophysica Acta. 1446: 419-25. PMID 10524219 DOI: 10.1016/S0167-4781(99)00092-5  0.464
1999 Gasparini S, DiFrancesco D. Action of serotonin on the hyperpolarization-activated cation current (Ih) in rat CA1 hippocampal neurons. The European Journal of Neuroscience. 11: 3093-100. PMID 10510173 DOI: 10.1046/j.1460-9568.1999.00728.x  0.57
1999 DiFrancesco D. Dual allosteric modulation of pacemaker (f) channels by cAMP and voltage in rabbit SA node. The Journal of Physiology. 515: 367-76. PMID 10050004 DOI: 10.1111/J.1469-7793.1999.367Ac.X  0.518
1998 Accili EA, Redaelli G, DiFrancesco D. Two distinct pathways of muscarinic current responses in rabbit sino-atrial node myocytes. PflüGers Archiv : European Journal of Physiology. 437: 164-7. PMID 9817803 DOI: 10.1007/s004240050763  0.433
1997 Gasparini S, DiFrancesco D. Action of the hyperpolarization-activated current (Ih) blocker ZD 7288 in hippocampal CA1 neurons. PflüGers Archiv : European Journal of Physiology. 435: 99-106. PMID 9359908 DOI: 10.1007/s004240050488  0.601
1997 Bois P, Renaudon B, Baruscotti M, Lenfant J, DiFrancesco D. Activation of f-channels by cAMP analogues in macropatches from rabbit sino-atrial node myocytes. The Journal of Physiology. 501: 565-71. PMID 9218217 DOI: 10.1111/j.1469-7793.1997.565bm.x  0.46
1997 Accili EA, Redaelli G, DiFrancesco D. Differential control of the hyperpolarization-activated current (i(f)) by cAMP gating and phosphatase inhibition in rabbit sino-atrial node myocytes. The Journal of Physiology. 500: 643-51. PMID 9161982 DOI: 10.1113/Jphysiol.1997.Sp022049  0.432
1997 Janigro D, Gasparini S, D'Ambrosio R, McKhann G, DiFrancesco D. Reduction of K+ uptake in glia prevents long-term depression maintenance and causes epileptiform activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2813-24. PMID 9092603 DOI: 10.1523/Jneurosci.17-08-02813.1997  0.604
1997 Accili EA, Robinson RB, DiFrancesco D. Properties and modulation of If in newborn versus adult cardiac SA node. The American Journal of Physiology. 272: H1549-52. PMID 9087633 DOI: 10.1152/Ajpheart.1997.272.3.H1549  0.412
1997 Baruscotti M, Westenbroek R, Catterall WA, DiFrancesco D, Robinson RB. The newborn rabbit sino-atrial node expresses a neuronal type I-like Na+ channel. The Journal of Physiology. 498: 641-8. PMID 9051576 DOI: 10.1113/Jphysiol.1997.Sp021889  0.431
1996 Zaza A, Robinson RB, DiFrancesco D. Basal responses of the L-type Ca2+ and hyperpolarization-activated currents to autonomic agonists in the rabbit sino-atrial node. The Journal of Physiology. 491: 347-55. PMID 8866859 DOI: 10.1113/Jphysiol.1996.Sp021220  0.374
1996 Zaza A, Rocchetti M, DiFrancesco D. Modulation of the hyperpolarization-activated current (I(f)) by adenosine in rabbit sinoatrial myocytes. Circulation. 94: 734-41. PMID 8772696 DOI: 10.1161/01.Cir.94.4.734  0.342
1996 Baruscotti M, DiFrancesco D, Robinson RB. A TTX-sensitive inward sodium current contributes to spontaneous activity in newborn rabbit sino-atrial node cells. The Journal of Physiology. 492: 21-30. PMID 8730579 DOI: 10.1113/Jphysiol.1996.Sp021285  0.437
1996 Mazzanti M, Assandri R, Ferroni A, DiFrancesco D. Cytoskeletal control of rectification and expression of four substates in cardiac inward rectifier K+ channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 357-61. PMID 8641571 DOI: 10.1096/Fasebj.10.2.8641571  0.478
1996 Accili EA, Redaelli G, DiFrancesco D. Activation of the hyperpolarization-activated current (if) in sino-atrial node myocytes of the rabbit by vasoactive intestinal peptide. PflüGers Archiv : European Journal of Physiology. 431: 803-5. PMID 8596736 DOI: 10.1007/BF02253849  0.43
1996 Accili EA, DiFrancesco D. Inhibition of the hyperpolarization-activated current (if) of rabbit SA node myocytes by niflumic acid. PflüGers Archiv : European Journal of Physiology. 431: 757-62. PMID 8596727 DOI: 10.1007/BF02253840  0.476
1996 Accili E, Redaelli G, DiFrancesco D. Activation of the hyperpolarization-activated current (i PflüGers Archiv European Journal of Physiology. 431: 803. DOI: 10.1007/s004240050071  0.375
1995 DiFrancesco D. Cardiac pacemaker: 15 years of "new" interpretation. Acta Cardiologica. 50: 413-27. PMID 8932564  0.326
1995 DiFrancesco D. Cesium and the pacemaker current. Journal of Cardiovascular Electrophysiology. 6: 1152-5. PMID 8720217 DOI: 10.1111/J.1540-8167.1995.Tb00394.X  0.384
1995 DiFrancesco D. The pacemaker current (I(f)) plays an important role in regulating SA node pacemaker activity. Cardiovascular Research. 30: 307-8. PMID 7585819 DOI: 10.1016/S0008-6363(95)00029-1  0.368
1995 DiFrancesco D. The onset and autonomic regulation of cardiac pacemaker activity: relevance of the f current. Cardiovascular Research. 29: 449-56. PMID 7540954 DOI: 10.1016/0008-6363(96)88518-X  0.419
1995 Moroni A, Bardella L, Difrancesco D. Expression of kat1, a plant inward-rectifying potassium channel, in xenopus oocytes Giornale Botanico Italiano. 129: 1068-1069. DOI: 10.1080/11263509509440940  0.375
1994 DiFrancesco D. Some properties of the UL-FS 49 block of the hyperpolarization-activated current (i(f)) in sino-atrial node myocytes. PflüGers Archiv : European Journal of Physiology. 427: 64-70. PMID 8058476 DOI: 10.1007/BF00585943  0.526
1994 Maccaferri G, Janigro D, Lazzari A, DiFrancesco D. Cesium prevents maintenance of long-term depression in rat hippocampal CA1 neurons. Neuroreport. 5: 1813-6. PMID 7827339 DOI: 10.1097/00001756-199409080-00032  0.601
1994 DiFrancesco D, Mangoni M. Modulation of single hyperpolarization-activated channels (i(f)) by cAMP in the rabbit sino-atrial node. The Journal of Physiology. 474: 473-82. PMID 7516974 DOI: 10.1113/Jphysiol.1994.Sp020038  0.53
1993 Hundal SP, DiFrancesco D, Mangoni M, Brammar WJ, Conley EC. An isoform of the cGMP-gated retinal photoreceptor channel gene expressed in the sinoatrial node (pacemaker) region of rabbit heart. Biochemical Society Transactions. 21: 119S. PMID 8359375 DOI: 10.1042/bst021119s  0.389
1993 Maccaferri G, Mangoni M, Lazzari A, DiFrancesco D. Properties of the hyperpolarization-activated current in rat hippocampal CA1 pyramidal cells. Journal of Neurophysiology. 69: 2129-36. PMID 7688802 DOI: 10.1152/Jn.1993.69.6.2129  0.678
1993 DiFrancesco D. Pacemaker mechanisms in cardiac tissue. Annual Review of Physiology. 55: 455-72. PMID 7682045 DOI: 10.1146/annurev.ph.55.030193.002323  0.406
1992 DiFrancesco D, Ducouret P, Robinson R. Differential effects of ACh on cardiac pacemaker cells. Trends in Neurosciences. 15: 249-50. PMID 1381117 DOI: 10.1016/0166-2236(92)90059-H  0.335
1992 Cui J, Mandel G, DiFrancesco D, Kline RP, Pennefather P, Datyner NB, Haspel HC, Cohen IS. Expression and characterization of a canine hippocampal inwardly rectifying K+ current in Xenopus oocytes. The Journal of Physiology. 457: 229-46. PMID 1338458 DOI: 10.1113/Jphysiol.1992.Sp019375  0.301
1992 Noble D, Denyer JC, Brown HF, DiFrancesco D. Reciprocal role of the inward currents ib, Na and i(f) in controlling and stabilizing pacemaker frequency of rabbit sino-atrial node cells. Proceedings. Biological Sciences / the Royal Society. 250: 199-207. PMID 1283636 DOI: 10.1098/rspb.1992.0150  0.435
1992 DiFRANCESCO D, Zaza A. The Cardiac Pacemaker Current if Journal of Cardiovascular Electrophysiology. 3: 334-344. DOI: 10.1111/J.1540-8167.1992.Tb00978.X  0.541
1991 Difrancesco D. Generation and control of cardiac pacing the pacemaker current. Trends in Cardiovascular Medicine. 1: 250-5. PMID 21239304 DOI: 10.1016/1050-1738(91)90030-I  0.449
1991 DiFrancesco D, Porciatti F, Janigro D, Maccaferri G, Mangoni M, Tritella T, Chang F, Cohen IS. Block of the cardiac pacemaker current (If) in the rabbit sino-atrial node and in canine Purkinje fibres by 9-amino-1,2,3,4-tetrahydroacridine. PflüGers Archiv : European Journal of Physiology. 417: 611-5. PMID 2057325 DOI: 10.1007/Bf00372959  0.694
1991 DiFrancesco D, Porciatti F, Cohen IS. The effects of manganese and barium on the cardiac pacemaker current, if, in rabbit sino-atrial node myocytes. Experientia. 47: 449-52. PMID 2044699 DOI: 10.1007/BF01959940  0.371
1991 DiFrancesco D. The contribution of the 'pacemaker' current (if) to generation of spontaneous activity in rabbit sino-atrial node myocytes. The Journal of Physiology. 434: 23-40. PMID 2023118 DOI: 10.1113/Jphysiol.1991.Sp018457  0.484
1991 Zaza A, Maccaferri G, Mangoni M, DiFrancesco D. Intracellular calcium does not directly modulate cardiac pacemaker (if) channels. PflüGers Archiv : European Journal of Physiology. 419: 662-4. PMID 1724077 DOI: 10.1007/Bf00370312  0.699
1991 DiFrancesco D, Tortora P. Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature. 351: 145-7. PMID 1709448 DOI: 10.1038/351145a0  0.523
1990 DIFRANCESCO D. The hyperpolarization-activated F-channel Cell Biology International Reports. 14: 40. DOI: 10.1016/0309-1651(90)90268-4  0.32
1989 DiFrancesco D, Ducouret P, Robinson RB. Muscarinic modulation of cardiac rate at low acetylcholine concentrations. Science (New York, N.Y.). 243: 669-71. PMID 2916119 DOI: 10.1126/Science.2916119  0.469
1989 Mazzanti M, DiFrancesco D. Intracellular Ca modulates K-inward rectification in cardiac myocytes. PflüGers Archiv : European Journal of Physiology. 413: 322-4. PMID 2717377 DOI: 10.1007/BF00581824  0.441
1988 DiFrancesco D, Tromba C. Inhibition of the hyperpolarization-activated current (if) induced by acetylcholine in rabbit sino-atrial node myocytes. The Journal of Physiology. 405: 477-91. PMID 3255798 DOI: 10.1113/Jphysiol.1988.Sp017343  0.44
1988 DiFrancesco D, Tromba C. Muscarinic control of the hyperpolarization-activated current (if) in rabbit sino-atrial node myocytes. The Journal of Physiology. 405: 493-510. PMID 2475609 DOI: 10.1113/Jphysiol.1988.Sp017344  0.426
1987 DiFrancesco D, Tromba C. Acetylcholine inhibits activation of the cardiac hyperpolarizing-activated current, if. PflüGers Archiv : European Journal of Physiology. 410: 139-42. PMID 2825112 DOI: 10.1007/BF00581906  0.424
1987 DiFrancesco D. The pacemaker current in the sinus node. European Heart Journal. 8: 19-23. PMID 2454189 DOI: 10.1093/Eurheartj/8.Suppl_L.19  0.488
1986 DiFrancesco D, Ferroni A, Mazzanti M, Tromba C. Properties of the hyperpolarizing-activated current (if) in cells isolated from the rabbit sino-atrial node. The Journal of Physiology. 377: 61-88. PMID 2432247 DOI: 10.1113/jphysiol.1986.sp016177  0.472
1986 DiFrancesco D. Characterization of single pacemaker channels in cardiac sino-atrial node cells. Nature. 324: 470-3. PMID 2431323 DOI: 10.1038/324470a0  0.541
1985 DiFrancesco D, Ferroni A, Visentin S, Zaza A. Cadmium-induced blockade of the cardiac fast Na channels in calf Purkinje fibres. Proceedings of the Royal Society of London. Series B, Biological Sciences. 223: 475-84. PMID 2580310 DOI: 10.1098/Rspb.1985.0013  0.425
1985 DiFrancesco D, Noble D. A model of cardiac electrical activity incorporating ionic pumps and concentration changes. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 353-98. PMID 2578676 DOI: 10.1098/Rstb.1985.0001  0.404
1985 DiFrancesco D. The cardiac hyperpolarizing-activated current, if. Origins and developments. Progress in Biophysics and Molecular Biology. 46: 163-83. PMID 2418458 DOI: 10.1016/0079-6107(85)90008-2  0.43
1984 DiFrancesco D. Properties of the cardiac pacemaker (if) current. Bollettino Della Società Italiana Di Biologia Sperimentale. 60: 29-33. PMID 6466486  0.328
1984 DiFrancesco D. Characterization of the pace-maker current kinetics in calf Purkinje fibres. The Journal of Physiology. 348: 341-67. PMID 6325672 DOI: 10.1113/jphysiol.1984.sp015114  0.448
1984 DiFrancesco D, Ferroni A, Visentin S. Barium-induced blockade of the inward rectifier in calf Purkinje fibres. PflüGers Archiv : European Journal of Physiology. 402: 446-53. PMID 6097875 DOI: 10.1007/BF00583946  0.408
1983 DiFrancesco D, Ferroni A. Delayed activation of the cardiac pacemaker current and its dependence on conditioning pre-hyperpolarizations. PflüGers Archiv : European Journal of Physiology. 396: 265-7. PMID 6302637 DOI: 10.1007/BF00587866  0.325
1983 Hart G, Noble D, DiFrancesco D. Implications of electrogenic Na/Ca exchange in mammalian heart: Computer model Journal of Molecular and Cellular Cardiology. 15: 83-83. DOI: 10.1016/0022-2828(83)91021-0  0.32
1982 DiFrancesco D. Block and activation of the pace-maker channel in calf purkinje fibres: effects of potassium, caesium and rubidium. The Journal of Physiology. 329: 485-507. PMID 6292407 DOI: 10.1113/Jphysiol.1982.Sp014315  0.46
1981 DiFrancesco D. A study of the ionic nature of the pace-maker current in calf Purkinje fibres. The Journal of Physiology. 314: 377-93. PMID 6273534 DOI: 10.1113/Jphysiol.1981.Sp013714  0.473
1981 DiFrancesco D. A new interpretation of the pace-maker current in calf Purkinje fibres. The Journal of Physiology. 314: 359-76. PMID 6273533 DOI: 10.1113/Jphysiol.1981.Sp013713  0.466
1980 Brown H, DiFrancesco D, Noble D, Noble S. The contribution of potassium accumulation to outward currents in frog atrium. The Journal of Physiology. 306: 127-49. PMID 7463357 DOI: 10.1113/Jphysiol.1980.Sp013388  0.387
1980 Brown H, Difrancesco D. Voltage-clamp investigations of membrane currents underlying pace-maker activity in rabbit sino-atrial node. The Journal of Physiology. 308: 331-51. PMID 7230019 DOI: 10.1113/Jphysiol.1980.Sp013474  0.449
1980 DiFrancesco D, Ojeda C. Properties of the current if in the sino-atrial node of the rabbit compared with those of the current iK, in Purkinje fibres. The Journal of Physiology. 308: 353-67. PMID 6262501  0.34
1980 DiFrancesco D, Noma A, Trautwein W. Separation of current induced by potassium accumulation from acetylcholine-induced relaxation current in the rabbit S-A node. PflüGers Archiv : European Journal of Physiology. 387: 83-90. PMID 6253876 DOI: 10.1007/BF00584257  0.38
1979 DiFrancesco D, McNaughton PA. The effects of calcium on outward membrane currents in the cardiac Purkinje fibre. The Journal of Physiology. 289: 347-73. PMID 458668 DOI: 10.1113/jphysiol.1979.sp012741  0.402
1979 Brown HF, DiFrancesco D, Noble SJ. How does adrenaline accelerate the heart? Nature. 280: 235-6. PMID 450140 DOI: 10.1038/280235a0  0.474
1979 Brown H, Difrancesco D, Noble S. Cardiac pacemaker oscillation and its modulation by autonomic transmitters. The Journal of Experimental Biology. 81: 175-204. PMID 315983  0.413
1978 DiFrancesco D, Ohba M. Dependence of the apparent reversal potential for the pace-maker current iK2 on its degree of activation in cardiac Purkinje fibres [proceedings]. The Journal of Physiology. 280: 73P-74P. PMID 690937  0.34
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