Thomas F. Gamage - Publications

Affiliations: 
2008-2014 Pharmacology and Toxicology Virginia Commonwealth University, Richmond, VA, United States 
 2014-2016 Center for Substance Abuse Research Temple University, Philadelphia, PA, United States 
 2016- Analytical Chemistry and Pharmaceutics RTI International 
Area:
molecular and behavioral pharmacology, allosteric modulation, cannabinoids, opioids, drug abuse, dependence

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wiley JL, Marusich JA, Blough BE, Namjoshi O, Brackeen M, Akinfiresoye LR, Walker TD, Prioleau C, Barrus DG, Gamage TF. Evaluation of cannabimimetic effects of selected minor cannabinoids and Terpenoids in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 132: 110984. PMID 38417478 DOI: 10.1016/j.pnpbp.2024.110984  0.57
2022 Marusich JA, Gamage TF, Zhang Y, Akinfiresoye LR, Wiley JL. In vitro and in vivo pharmacology of nine novel synthetic cannabinoid receptor agonists. Pharmacology, Biochemistry, and Behavior. 220: 173467. PMID 36154844 DOI: 10.1016/j.pbb.2022.173467  0.634
2022 Finlay DB, Nguyen T, Gamage TF, Chen S, Barrus DG, Patel PR, Thomas BF, Wiley JL, Zhang Y, Glass M. Exploring determinants of agonist efficacy at the CB1 cannabinoid receptor: Analogues of the synthetic cannabinoid receptor agonist EG-018. Pharmacology Research & Perspectives. 10: e00901. PMID 35041297 DOI: 10.1002/prp2.901  0.716
2021 Nguyen T, Gamage TF, Decker AM, Finlay DB, Langston TL, Barrus D, Glass M, Harris DL, Zhang Y. Rational design of cannabinoid type-1 receptor allosteric modulators: Org27569 and PSNCBAM-1 hybrids. Bioorganic & Medicinal Chemistry. 41: 116215. PMID 34015703 DOI: 10.1016/j.bmc.2021.116215  0.335
2020 Wiley JL, Barrus DG, Farquhar CE, Lefever TW, Gamage TF. Sex, species and age: Effects of rodent demographics on the pharmacology of ∆-tetrahydrocanabinol. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110064. PMID 32810571 DOI: 10.1016/J.Pnpbp.2020.110064  0.624
2020 Gamage TF, Barrus DG, Kevin RC, Finlay DB, Lefever TW, Patel PR, Grabenauer MA, Glass M, McGregor IS, Wiley JL, Thomas BF. In vitro and in vivo pharmacological evaluation of the synthetic cannabinoid receptor agonist EG-018. Pharmacology, Biochemistry, and Behavior. 172918. PMID 32247816 DOI: 10.1016/J.Pbb.2020.172918  0.756
2019 Nguyen T, Gamage T, Decker AM, Barrus D, Langston TL, Li JX, Thomas BF, Zhang Y. Synthesis and Pharmacological Evaluation of 1-Phenyl-3-Thiophenylurea Derivatives as Cannabinoid Type-1 Receptor Allosteric Modulators. Journal of Medicinal Chemistry. PMID 31596583 DOI: 10.1021/Acs.Jmedchem.9B01161  0.639
2019 Kevin RC, Kovach AL, Lefever TW, Gamage TF, Wiley JL, McGregor IS, Thomas BF. Toxic by design? Formation of thermal degradants and cyanide from carboxamide-type synthetic cannabinoids CUMYL-PICA, 5F-CUMYL-PICA, AMB-FUBINACA, MDMB-FUBINACA, NNEI, and MN-18 during exposure to high temperatures. Forensic Toxicology. 37: 17-26. PMID 30705707 DOI: 10.1007/S11419-018-0430-0  0.631
2018 Gamage TF, Farquhar CE, McKinnie RJ, Kevin RC, McGregor IS, Trudell M, Wiley JL, Thomas BF. Synthetic cannabinoid hydroxypentyl metabolites retain efficacy at human cannabinoid receptors. The Journal of Pharmacology and Experimental Therapeutics. PMID 30552295 DOI: 10.1124/Jpet.118.254425  0.728
2018 Farquhar CE, Breivogel CS, Gamage TF, Gay EA, Thomas BF, Craft RM, Wiley JL. Sex, THC, and hormones: Effects on density and sensitivity of CB cannabinoid receptors in rats. Drug and Alcohol Dependence. 194: 20-27. PMID 30391834 DOI: 10.1016/J.Drugalcdep.2018.09.018  0.675
2018 Nguyen T, Gamage TF, Decker AM, German N, Langston TL, Farquhar CE, Kenakin TP, Wiley JL, Thomas BF, Zhang Y. Diarylureas Containing 5-Membered Heterocycles as CB1 Receptor Allosteric Modulators: Design, Synthesis, and Pharmacological Evaluation. Acs Chemical Neuroscience. PMID 30188693 DOI: 10.1021/Acschemneuro.8B00396  0.711
2018 Gamage TF, Farquhar CE, Lefever TW, Marusich JA, Kevin RC, McGregor IS, Wiley JL, Thomas BF. Molecular and behavioral pharmacological characterization of abused synthetic cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-fluoro-CUMYL-PICA. The Journal of Pharmacology and Experimental Therapeutics. PMID 29549157 DOI: 10.1124/Jpet.117.246983  0.743
2017 Kevin RC, Lefever TW, Snyder RW, Patel PR, Gamage TF, Fennell TR, Wiley JL, McGregor IS, Thomas BF. Kinetic and metabolic profiles of synthetic cannabinoids NNEI and MN-18. Drug Testing and Analysis. PMID 28834241 DOI: 10.1002/Dta.2262  0.667
2017 Gamage TF, Farquhar CE, Lefever TW, Thomas BF, Nguyen T, Zhang Y, Wiley JL. The great divide: Separation between in vitro and in vivo effects of PSNCBAM-based CB1 receptor allosteric modulators. Neuropharmacology. PMID 28803965 DOI: 10.1016/J.Neuropharm.2017.08.008  0.748
2017 Nguyen T, German N, Decker AM, Langston TL, Gamage TF, Farquhar CE, Li JX, Wiley JL, Thomas BF, Zhang Y. Novel Diarylurea Based Allosteric Modulators of the Cannabinoid CB1 Receptor: Evaluation of Importance of 6-Pyrrolidinylpyridinyl Substitution. Journal of Medicinal Chemistry. PMID 28792219 DOI: 10.1021/Acs.Jmedchem.7B00707  0.732
2017 Thomas BF, Lefever TW, Cortes RA, Kovach AL, Cox AO, Patel PR, Pollard GT, Marusich JA, Kevin RA, Gamage TF, Wiley JL. Thermolytic degradation of synthetic cannabinoids: chemical exposures and pharmacological consequences. The Journal of Pharmacology and Experimental Therapeutics. PMID 28087785 DOI: 10.1124/Jpet.116.238717  0.705
2016 Gamage TF, Anderson JC, Abood ME. CB1 allosteric modulator Org27569 is an antagonist/inverse agonist of ERK1/2 signaling. Cannabis and Cannabinoid Research. 1: 272-280. PMID 28660254 DOI: 10.1089/can.2016.0028  0.611
2016 Meza-Aviña ME, Lingerfelt MA, Console-Bram LM, Gamage TF, Sharir H, Gettys KE, Hurst DP, Kotsikorou E, Shore DM, Caron MG, Rao N, Barak LS, Abood ME, Reggio PH, Croatt MP. Design, synthesis, and analysis of antagonists of GPR55: Piperidine-substituted 1,3,4-oxadiazol-2-ones. Bioorganic & Medicinal Chemistry Letters. PMID 26916440 DOI: 10.1016/J.Bmcl.2016.02.030  0.619
2015 Gamage TF, Ignatowska-Jankowska BM, Muldoon PP, Cravatt BF, Damaj MI, Lichtman AH. Differential effects of endocannabinoid catabolic inhibitors on morphine withdrawal in mice. Drug and Alcohol Dependence. 146: 7-16. PMID 25479915 DOI: 10.1016/J.Drugalcdep.2014.11.015  0.731
2014 Gamage TF, Ignatowska-Jankowska BM, Wiley JL, Abdelrahman M, Trembleau L, Greig IR, Thakur GA, Tichkule R, Poklis J, Ross RA, Pertwee RG, Lichtman AH. In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569. Behavioural Pharmacology. 25: 182-5. PMID 24603340 DOI: 10.1097/Fbp.0000000000000027  0.795
2013 Ramesh D, Gamage TF, Vanuytsel T, Owens RA, Abdullah RA, Niphakis MJ, Shea-Donohue T, Cravatt BF, Lichtman AH. Dual inhibition of endocannabinoid catabolic enzymes produces enhanced antiwithdrawal effects in morphine-dependent mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1039-49. PMID 23303065 DOI: 10.1038/Npp.2012.269  0.74
2012 Wise LE, Premaratne ID, Gamage TF, Lichtman AH, Hughes LD, Harris LS, Aceto MD. l-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice. Pharmacology, Biochemistry, and Behavior. 103: 245-52. PMID 22935630 DOI: 10.1016/J.Pbb.2012.08.008  0.705
2012 Gamage TF, Lichtman AH. The endocannabinoid system: role in energy regulation. Pediatric Blood & Cancer. 58: 144-8. PMID 22076835 DOI: 10.1002/Pbc.23367  0.477
2012 Vann RE, Walentiny DM, Burston JJ, Tobey KM, Gamage TF, Wiley JL. Enhancement of the behavioral effects of endogenous and exogenous cannabinoid agonists by phenylmethyl sulfonyl fluoride. Neuropharmacology. 62: 1019-27. PMID 22051632 DOI: 10.1016/J.Neuropharm.2011.10.011  0.771
2011 Walentiny DM, Gamage TF, Warner JA, Nguyen TK, Grainger DB, Wiley JL, Vann RE. The endogenous cannabinoid anandamide shares discriminative stimulus effects with ∆(9)-tetrahydrocannabinol in fatty acid amide hydrolase knockout mice. European Journal of Pharmacology. 656: 63-7. PMID 21300050 DOI: 10.1016/J.Ejphar.2011.01.056  0.759
2010 Jackson KJ, Marks MJ, Vann RE, Chen X, Gamage TF, Warner JA, Damaj MI. Role of alpha5 nicotinic acetylcholine receptors in pharmacological and behavioral effects of nicotine in mice. The Journal of Pharmacology and Experimental Therapeutics. 334: 137-46. PMID 20400469 DOI: 10.1124/Jpet.110.165738  0.319
2008 Vann RE, Gamage TF, Warner JA, Marshall EM, Taylor NL, Martin BR, Wiley JL. Divergent effects of cannabidiol on the discriminative stimulus and place conditioning effects of Delta(9)-tetrahydrocannabinol. Drug and Alcohol Dependence. 94: 191-8. PMID 18206320 DOI: 10.1016/J.Drugalcdep.2007.11.017  0.666
2006 Wright MJ, Vann RE, Gamage TF, Damaj MI, Wiley JL. Comparative effects of dextromethorphan and dextrorphan on nicotine discrimination in rats. Pharmacology, Biochemistry, and Behavior. 85: 507-13. PMID 17112574 DOI: 10.1016/J.Pbb.2006.09.020  0.604
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