☰

Benjamin A. Nacev, MD Ph.D. - Publications

Affiliations: 
2022- University of Pittsburgh School of Medicine, Pittsburgh, PA, United States 
Area:
Chromatin Biology
Website:
https://nacevlab.com/
Tree Info Similar researchers PubMed Report error

20/39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Bagert JD, Mitchener MM, Patriotis AL, Dul BE, Wojcik F, Nacev BA, Feng L, Allis CD, Muir TW. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nature Chemical Biology. PMID 33649601 DOI: 10.1038/s41589-021-00738-1  0.461
2020 Nacev BA, Jones KB, Intlekofer AM, Yu JSE, Allis CD, Tap WD, Ladanyi M, Nielsen TO. The epigenomics of sarcoma. Nature Reviews. Cancer. PMID 32782366 DOI: 10.1038/S41568-020-0288-4  0.496
2019 Nacev BA, Feng L, Bagert JD, Lemiesz AE, Gao J, Soshnev AA, Kundra R, Schultz N, Muir TW, Allis CD. The expanding landscape of 'oncohistone' mutations in human cancers. Nature. PMID 30894748 DOI: 10.1038/S41586-019-1038-1  0.701
2018 Nacev BA, Tap WD. TOMAS: revisiting PARP inhibitor combination therapy. The Lancet. Oncology. PMID 30217674 DOI: 10.1016/S1470-2045(18)30494-7  0.323
2017 Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis. Acs Chemical Biology. 12: 174-182. PMID 28103683 DOI: 10.1021/Acschembio.6B00849  0.644
2015 Kshitiz, Afzal J, Suhail Y, Ahn EH, Goyal R, Hubbi ME, Hussaini Q, Ellison DD, Goyal J, Nacev B, Kim DH, Lee JH, Frankel S, Gray K, Bankoti R, et al. Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins. Integrative Biology : Quantitative Biosciences From Nano to Macro. 7: 364-72. PMID 25784457 DOI: 10.1039/C4Ib00209A  0.357
2015 Pandey R, Botros MA, Nacev BA, Albig AR. Cyclosporin a disrupts notch signaling and vascular lumen maintenance. Plos One. 10: e0119279. PMID 25775018 DOI: 10.1371/Journal.Pone.0119279  0.435
2015 Chi P, Qin L, Kelly CM, D'Angelo SP, Dickson MA, Gounder MM, Keohan ML, Movva S, Nacev B, Crago AM, Yoon SS, Ulaner GA, Martindale M, Condy MM, Phelan H, et al. A phase II study of MEK162 (binimetinib [BINI]) in combination with imatinib in patients with untreated advanced gastrointestinal stromal tumor (GIST). Journal of Clinical Oncology. 33: 10507-10507. DOI: 10.1200/Jco.2020.38.15_Suppl.11508  0.364
2013 Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016. PMID 23634668 DOI: 10.1021/Jm400227Z  0.74
2012 Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. Abstract 2316: Itraconazole, an antifungal drug with anti-angiogenic activity, inhibits VEGFR2 trafficking, glycosylation, and signaling in endothelial cells Cancer Research. 72: 2316-2316. DOI: 10.1158/1538-7445.Am2012-2316  0.58
2011 Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. The Journal of Biological Chemistry. 286: 44045-56. PMID 22025615 DOI: 10.1074/Jbc.M111.278754  0.569
2011 Nacev BA, Liu JO. Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole. Plos One. 6: e24793. PMID 21969860 DOI: 10.1371/Journal.Pone.0024793  0.541
2011 Shi W, Nacev BA, Aftab BT, Head S, Rudin CM, Liu JO. Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling. Journal of Medicinal Chemistry. 54: 7363-74. PMID 21936514 DOI: 10.1021/Jm200944B  0.779
2011 Nacev BA, Low WK, Huang Z, Su TT, Su Z, Alkuraya H, Kasuga D, Sun W, Träger M, Braun M, Fischer G, Zhang K, Liu JO. A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog. The Journal of Pharmacology and Experimental Therapeutics. 338: 466-75. PMID 21562139 DOI: 10.1124/Jpet.111.180851  0.796
2011 Wilson BA, Wang H, Nacev BA, Mease RC, Liu JO, Pomper MG, Isaacs WB. High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S). Molecular Cancer Therapeutics. 10: 825-38. PMID 21441411 DOI: 10.1158/1535-7163.Mct-10-0902  0.443
2011 Aftab BT, Shi W, Nacev BA, Head S, Liu JO, Rudin CM. Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C147  0.785
2010 Shi W, Nacev BA, Bhat S, Liu JO. Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole. Acs Medicinal Chemistry Letters. 1: 155-159. PMID 21892383 DOI: 10.1021/Ml1000068  0.711
2010 Shim JS, Matsui Y, Bhat S, Nacev BA, Xu J, Bhang HE, Dhara S, Han KC, Chong CR, Pomper MG, So A, Liu JO. Effect of nitroxoline on angiogenesis and growth of human bladder cancer. Journal of the National Cancer Institute. 102: 1855-73. PMID 21088277 DOI: 10.1093/Jnci/Djq457  0.741
2010 Xiao Q, Zhang F, Nacev BA, Liu JO, Pei D. Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases. Biochemistry. 49: 5588-99. PMID 20521764 DOI: 10.1021/Bi1005464  0.607
2009 Liu JO, Nacev BA, Xu J, Bhat S. It takes two binding sites for calcineurin and NFAT to tango. Molecular Cell. 33: 676-8. PMID 19328062 DOI: 10.1016/J.Molcel.2009.03.005  0.659
Low-probability matches (unlikely to be authored by this person)
2002 Ouyang B, Knauf JA, Ain K, Nacev B, Fagin JA. Mechanisms of aneuploidy in thyroid cancer cell lines and tissues: evidence for mitotic checkpoint dysfunction without mutations in BUB1 and BUBR1. Clinical Endocrinology. 56: 341-50. PMID 11940046 DOI: 10.1046/J.1365-2265.2002.01475.X  0.256
2020 Rosenbaum E, Seier K, Bandlamudi C, Dickson MA, Gounder MM, Keohan ML, Chi P, Kelly C, Movva S, Nacev B, Simeone N, Donoghue MTA, Slotkin EK, Qin LX, Antonescu CR, et al. HLA Genotyping in Synovial Sarcoma: Identifying HLA-A*02 and its Association with Clinical Outcome. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32816945 DOI: 10.1200/Jco.2020.38.15_Suppl.E23560  0.212
2022 Nacev BA, Sanchez-Vega F, Smith SA, Antonescu CR, Rosenbaum E, Shi H, Tang C, Socci ND, Rana S, Gularte-Mérida R, Zehir A, Gounder MM, Bowler TG, Luthra A, Jadeja B, et al. Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets. Nature Communications. 13: 3405. PMID 35705560 DOI: 10.1038/s41467-022-30453-x  0.192
2020 Rosenbaum E, Seier K, Kelly CM, Kiesler H, Martindale M, Nicholls C, Chi P, Dickson MA, Gounder MM, Keohan ML, Movva S, Nacev B, Hwang S, Qin L, D'Angelo SP, et al. Association of immune-related adverse events (irAEs) with improved clinical outcome in sarcoma patients treated with immune checkpoint blockade (ICB). Journal of Clinical Oncology. 38: 11510-11510. DOI: 10.1200/Jco.2020.38.15_Suppl.11510  0.192
2023 Kelly CM, Qin LX, Whiting KA, Richards AL, Avutu V, Chan JE, Chi P, Dickson MA, Gounder MM, Keohan ML, Movva S, Nacev BA, Rosenbaum E, Adamson T, Singer S, et al. A phase 2 study of epacadostat and pembrolizumab in patients with advanced sarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36971773 DOI: 10.1158/1078-0432.CCR-22-3911  0.182
2014 Crompton JG, Nacev BA, Upham T, Azoury SC, Eil R, Cameron DE, Haider AH. Traumatic ventricular septal defect resulting in severe pulmonary hypertension. Journal of Surgical Case Reports. 2014. PMID 25326917 DOI: 10.1093/Jscr/Rju107  0.177
2023 Fang Y, Barrows D, Dabas Y, Carroll TS, Tap WD, Nacev BA. ATRX guards against aberrant differentiation in mesenchymal progenitor cells. Biorxiv : the Preprint Server For Biology. PMID 37609273 DOI: 10.1101/2023.08.08.552433  0.173
2024 Fang Y, Barrows D, Dabas Y, Carroll TS, Singer S, Tap WD, Nacev BA. ATRX guards against aberrant differentiation in mesenchymal progenitor cells. Nucleic Acids Research. PMID 38477352 DOI: 10.1093/nar/gkae160  0.171
2021 Angeles CV, Velez A, Rios J, Laxa B, Shum D, Ruiz PD, Shen Y, Ostrovnaya I, Gularte-Mérida R, Nacev BA, Dickson MA, Djaballah H, Okada T, Singer S. A High-Content Screen for C/EBPα Expression Identifies Novel Therapeutic Agents in Dedifferentiated Liposarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34667024 DOI: 10.1158/1078-0432.CCR-19-2486  0.155
2022 Chi P, Qin LX, Nguyen B, Kelly CM, D'Angelo SP, Dickson MA, Gounder MM, Keohan ML, Movva S, Nacev BA, Rosenbaum E, Thornton KA, Crago AM, Yoon S, Ulaner G, et al. Phase II Trial of Imatinib Plus Binimetinib in Patients With Treatment-Naive Advanced Gastrointestinal Stromal Tumor. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2102029. PMID 35041493 DOI: 10.1200/JCO.21.02029  0.154
2022 D'Angelo SP, Richards AL, Conley AP, Woo HJ, Dickson MA, Gounder M, Kelly C, Keohan ML, Movva S, Thornton K, Rosenbaum E, Chi P, Nacev B, Chan JE, Slotkin EK, et al. Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma. Nature Communications. 13: 3477. PMID 35710741 DOI: 10.1038/s41467-022-30874-8  0.114
2022 Dermawan JK, Singer S, Tap WD, Nacev BA, Chi P, Wexler LH, Ortiz MV, Gounder M, Antonescu CR. The genetic landscape of SMARCB1 alterations in SMARCB1-deficient spectrum of mesenchymal neoplasms. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 36088476 DOI: 10.1038/s41379-022-01148-x  0.108
2022 Chi P, Qin LX, Camacho N, Kelly CM, D'Angelo SP, Dickson MA, Gounder MM, Keohan ML, Movva S, Nacev BA, Rosenbaum E, Thornton KA, Crago AM, Francis JH, Martindale M, et al. Phase Ib Trial of the Combination of Imatinib and Binimetinib in Patients with Advanced Gastrointestinal Stromal Tumors (GIST). Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 35110417 DOI: 10.1158/1078-0432.CCR-21-3909  0.082
2022 Rosenbaum E, Antonescu CR, Smith S, Bradic M, Kashani D, Richards AL, Donoghue M, Kelly CM, Nacev B, Chan JE, Chi P, Dickson MA, Keohan ML, Gounder MM, Movva S, et al. Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center. Journal For Immunotherapy of Cancer. 10. PMID 35365586 DOI: 10.1136/jitc-2021-004149  0.077
2023 Rosenbaum E, Seier K, Bradic M, Kelly C, Movva S, Nacev BA, Gounder MM, Keohan ML, Avutu V, Chi P, Thornton KA, Chan JE, Dickson MA, Donoghue MTA, Tap WD, et al. Immune-related Adverse Events after Immune Checkpoint Blockade-based Therapy Are Associated with Improved Survival in Advanced Sarcomas. Cancer Research Communications. 3: 2118-2125. PMID 37787759 DOI: 10.1158/2767-9764.CRC-22-0140  0.068
2020 Rosenbaum E, Seier K, Bandlamudi C, Chi P, Dickson MA, Gounder MM, Kelly CM, Keohan ML, Movva S, Nacev B, Slotkin EK, Simeone N, Donoghue M, Qin L, Antonescu CR, et al. HLA genotyping in synovial sarcoma: Identifying HLA-A*02 and its association with clinical outcome. Journal of Clinical Oncology. 38: e23560-e23560. DOI: 10.1200/jco.2020.38.15_suppl.e23560  0.065
2021 Klemen ND, Hwang S, Bradic M, Rosenbaum E, Dickson MA, Gounder MM, Kelly CM, Keohan ML, Movva S, Thornton KA, Chi P, Nacev BA, Chan JE, Bartlett EK, Richards AL, et al. Long term follow-up and patterns of response, progression and hyperprogression in patients after PD-1 blockade in advanced sarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 34965948 DOI: 10.1158/1078-0432.CCR-21-3445  0.062
2020 Rosenbaum E, Jonsson P, Seier K, Qin LX, Chi P, Dickson M, Gounder M, Kelly C, Keohan ML, Nacev B, Donoghue MTA, Chiang S, Singer S, Ladanyi M, Antonescu CR, et al. Clinical Outcome of Leiomyosarcomas With Somatic Alteration in Homologous Recombination Pathway Genes. Jco Precision Oncology. 4. PMID 33283135 DOI: 10.1200/PO.20.00122  0.042
2023 Lebow ES, Lobaugh SM, Zhang Z, Dickson MA, Rosenbaum E, D'Angelo SP, Nacev BA, Shepherd AF, Shaverdian N, Wolden S, Wu AJ, Gelblum DY, Simone Ii CB, Gomez DR, Alektiar K, et al. Stereotactic body radiation therapy for sarcoma pulmonary metastases. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. 109824. PMID 37532104 DOI: 10.1016/j.radonc.2023.109824  0.017
Hide low-probability matches.