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Brenna C. Carey, Ph.D. - Publications

Affiliations: 
2003 University of Cincinnati, Cincinnati, OH 
Area:
Immunology, Molecular Biology
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42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Arumugam P, Carey BC, Wikenheiser-Brokamp KA, Krischer J, Wessendarp M, Shima K, Chalk C, Stock J, Ma Y, Black D, Imbrogno M, Collins M, Kalenda Yombo DJ, Sakthivel H, Suzuki T, et al. A toxicology study of complementation and pulmonary macrophage transplantation therapy of hereditary PAP in mice. Molecular Therapy. Methods & Clinical Development. 32: 101213. PMID 38596536 DOI: 10.1016/j.omtm.2024.101213  0.359
2024 Brugnoli B, Salvati L, Di Lauria N, Botta A, Tozzetti C, Biscarini A, Capone M, Ferrentino F, Naldi C, Ascione G, Mazzoni A, Maggi L, Campo I, Carey B, Trapnell B, et al. Disseminated nocardiosis and anti-GM-CSF antibodies. European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology. PMID 38379052 DOI: 10.1007/s10096-024-04785-z  0.305
2023 Neehus AL, Carey B, Landekic M, Panikulam P, Deutsch G, Ogishi M, Arango-Franco CA, Philippot Q, Modaresi M, Mohammadzadeh I, Corcini Berndt M, Rinchai D, Le Voyer T, Rosain J, Momenilandi M, et al. Human inherited CCR2 deficiency underlies progressive polycystic lung disease. Cell. PMID 38157855 DOI: 10.1016/j.cell.2023.11.036  0.381
2023 Campo I, Carey BC, Paracchini E, Kadija Z, De Silvestri A, Rodi G, De Amici M, Torre C, Zorzetto M, Griese M, Meloni F, Corsico AG, Trapnell BC, Mariani F. Inhaled GM-CSF reduces the need for whole lung lavage and improves gas exchange in autoimmune PAP patients. The European Respiratory Journal. PMID 37973175 DOI: 10.1183/13993003.01233-2023  0.428
2022 McCarthy C, Carey B, Trapnell BC. Autoimmune Pulmonary Alveolar Proteinosis. American Journal of Respiratory and Critical Care Medicine. PMID 35227171 DOI: 10.1164/rccm.202112-2742SO  0.408
2022 Shima K, Arumugam P, Sallese A, Horia Y, Ma Y, Trapnell C, Wessendarp M, Chalk C, McCarthy C, Carey BC, Trapnell BC, Suzuki T. A Murine Model of Hereditary Pulmonary Alveolar Proteinosis Caused by Homozygous Csf2ra Gene Disruption. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 35043685 DOI: 10.1152/ajplung.00175.2021  0.408
2021 Ataya A, Knight V, Carey BC, Lee E, Tarling EJ, Wang T. The Role of GM-CSF Autoantibodies in Infection and Autoimmune Pulmonary Alveolar Proteinosis: A Concise Review. Frontiers in Immunology. 12: 752856. PMID 34880857 DOI: 10.3389/fimmu.2021.752856  0.409
2021 Cheah FC, Presicce P, Tan TL, Carey BC, Kallapur SG. Studying the Effects of Granulocyte-Macrophage Colony-Stimulating Factor on Fetal Lung Macrophages During the Perinatal Period Using the Mouse Model. Frontiers in Pediatrics. 9: 614209. PMID 33777863 DOI: 10.3389/fped.2021.614209  0.415
2020 Bonaventura A, Vecchié A, Wang TS, Lee E, Cremer PC, Carey B, Rajendram P, Hudock KM, Korbee L, Van Tassell BW, Dagna L, Abbate A. Targeting GM-CSF in COVID-19 Pneumonia: Rationale and Strategies. Frontiers in Immunology. 11: 1625. PMID 32719685 DOI: 10.3389/Fimmu.2020.01625  0.466
2019 Schulert GS, Yasin S, Carey B, Chalk C, Do T, Schapiro AH, Husami A, Watts A, Brunner HI, Huggins J, Mellins ED, Morgan EM, Ting T, Trapnell BC, Wikenheiser-Brokamp KA, et al. Systemic Juvenile Idiopathic Arthritis-Lung Disease: Characterization and Risk Factors. Arthritis & Rheumatology (Hoboken, N.J.). PMID 31379071 DOI: 10.1002/Art.41073  0.322
2019 Arumugam P, Suzuki T, Shima K, McCarthy C, Sallese A, Wessendarp M, Ma Y, Meyer J, Black D, Chalk C, Carey B, Lachmann N, Moritz T, Trapnell BC. Long-Term Safety and Efficacy of Gene-Pulmonary Macrophage Transplantation Therapy of PAP in Csf2ra Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31326401 DOI: 10.1016/J.Ymthe.2019.06.010  0.437
2019 Suzuki T, McCarthy C, Carey B, Borchers M, Beck D, Wikenheiser-Brokamp KA, Black D, Chalk C, Trapnell BC. Increased Pulmonary GM-CSF Causes Alveolar Macrophage Accumulation: Mechanistic Implications for Desquamative Interstitial Pneumonitis. American Journal of Respiratory Cell and Molecular Biology. PMID 31310562 DOI: 10.1165/Rcmb.2018-0294Oc  0.489
2019 Anderson K, Carey B, Martin A, Roark C, Chalk C, Nowell-Bostic M, Freed B, Aubrey M, Trapnell B, Fontenot A. Pulmonary alveolar proteinosis: An autoimmune disease lacking an HLA association. Plos One. 14: e0213179. PMID 30845238 DOI: 10.1371/Journal.Pone.0213179  0.415
2019 McCarthy C, Carey B, Trapnell BC. Blood Testing for Differential Diagnosis of Pulmonary Alveolar Proteinosis Syndrome. Chest. 155: 450-452. PMID 30732696 DOI: 10.1016/J.Chest.2018.11.002  0.352
2018 McCarthy C, Carey B, Trapnell BC. Blood testing in the diagnosis of pulmonary alveolar proteinosis. The Lancet. Respiratory Medicine. 6: e54. PMID 30484430 DOI: 10.1016/S2213-2600(18)30372-2  0.348
2018 McCarthy C, Lee E, Bridges JP, Sallese A, Suzuki T, Woods JC, Bartholmai BJ, Wang T, Chalk C, Carey BC, Arumugam P, Shima K, Tarling EJ, Trapnell BC. Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis. Nature Communications. 9: 3127. PMID 30087322 DOI: 10.1038/S41467-018-05491-Z  0.452
2018 McCarthy C, Avetisyan R, Carey BC, Chalk C, Trapnell BC. Prevalence and healthcare burden of pulmonary alveolar proteinosis. Orphanet Journal of Rare Diseases. 13: 129. PMID 30064481 DOI: 10.1186/S13023-018-0846-Y  0.392
2017 Sallese A, Suzuki T, McCarthy C, Bridges J, Filuta A, Arumugam P, Shima K, Ma Y, Wessendarp M, Black D, Chalk C, Carey B, Trapnell BC. Targeting cholesterol homeostasis in lung diseases. Scientific Reports. 7: 10211. PMID 28860566 DOI: 10.1038/S41598-017-10879-W  0.453
2017 Hetzel M, Suzuki T, Hashtchin AR, Arumugam P, Carey B, Schwabbauer M, Kuhn A, Meyer J, Schambach A, Van Der Loo J, Moritz T, Trapnell BC, Lachmann N. Function and safety of lentivirus-mediated gene transfer for CSF2RA-deficiency. Human Gene Therapy Methods. PMID 28854814 DOI: 10.1089/hgtb.2017.092  0.391
2016 Arumugam PI, Suzuki T, Sallese A, Lachmann N, Chalk C, Black D, Carey B, Moritz T, Trapnell BC. 35. Establishment of the Dose-Response Relationship Needed for Human Translation of Pulmonary Macrophage Transplantation (PMT) Therapy of Hereditary Pulmonary Alveolar Proteinosis (hPAP) Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32844-1  0.422
2016 Suzuki T, Arumugam P, Sallese A, Lachmann N, Chalk C, Black D, Carey B, Moritz T, Trapnell BC. 21. Pulmonary Macrophage Transplantation (PMT) Therapy of Hereditary Pulmonary Alveolar Proteinosis (hPAP) Is Effective with Mature Macrophages and Does Not Require Myeloid Precursor/Progenitor Expansion Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32830-1  0.461
2015 Suzuki T, Sallese A, Chalk C, Carey B, Lutzko C, Trapnell B. 12. GM-CSF But Not M-CSF is Critical to the Therapeutic Mechanism of Action and Efficacy of Pulmonary Macrophage Transplantation (PMT) Therapy of Hereditary Pulmonary Alveolar Proteinosis (hPAP) Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33616-4  0.474
2014 Cummings KJ, Virji MA, Trapnell BC, Carey B, Healey T, Kreiss K. Early changes in clinical, functional, and laboratory biomarkers in workers at risk of indium lung disease. Annals of the American Thoracic Society. 11: 1395-403. PMID 25295756 DOI: 10.1513/Annalsats.201407-346Oc  0.326
2014 Suzuki T, Arumugam P, Sakagami T, Lachmann N, Chalk C, Sallese A, Abe S, Trapnell C, Carey B, Moritz T, Malik P, Lutzko C, Wood RE, Trapnell BC. Pulmonary macrophage transplantation therapy. Nature. 514: 450-4. PMID 25274301 DOI: 10.1038/Nature13807  0.481
2014 Kusakabe Y, Uchida K, Hiruma T, Suzuki Y, Totsu T, Suzuki T, Carey BC, Yamada Y, Trapnell BC. A standardized blood test for the routine clinical diagnosis of impaired GM-CSF signaling using flow cytometry. Journal of Immunological Methods. 413: 1-11. PMID 25068538 DOI: 10.1016/J.Jim.2014.07.009  0.4
2014 Suzuki T, Mayhew C, Sallese A, Chalk C, Carey BC, Malik P, Wood RE, Trapnell BC. Use of induced pluripotent stem cells to recapitulate pulmonary alveolar proteinosis pathogenesis. American Journal of Respiratory and Critical Care Medicine. 189: 183-93. PMID 24279752 DOI: 10.1164/Rccm.201306-1039Oc  0.483
2014 Uchida K, Nakata K, Carey B, Chalk C, Suzuki T, Sakagami T, Koch DE, Stevens C, Inoue Y, Yamada Y, Trapnell BC. Standardized serum GM-CSF autoantibody testing for the routine clinical diagnosis of autoimmune pulmonary alveolar proteinosis. Journal of Immunological Methods. 402: 57-70. PMID 24275678 DOI: 10.1016/J.Jim.2013.11.011  0.393
2013 Mueller C, Chulay JD, Trapnell BC, Humphries M, Carey B, Sandhaus RA, McElvaney NG, Messina L, Tang Q, Rouhani FN, Campbell-Thompson M, Fu AD, Yachnis A, Knop DR, Ye GJ, et al. Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression. The Journal of Clinical Investigation. 123: 5310-8. PMID 24231351 DOI: 10.1172/Jci70314  0.32
2011 Flotte TR, Trapnell BC, Humphries M, Carey B, Calcedo R, Rouhani F, Campbell-Thompson M, Yachnis AT, Sandhaus RA, McElvaney NG, Mueller C, Messina LM, Wilson JM, Brantly M, Knop DR, et al. Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results. Human Gene Therapy. 22: 1239-47. PMID 21609134 DOI: 10.1089/Hum.2011.053  0.339
2011 Wu H, Suzuki T, Carey B, Trapnell BC, McCormack FX. Keratinocyte growth factor augments pulmonary innate immunity through epithelium-driven, GM-CSF-dependent paracrine activation of alveolar macrophages. The Journal of Biological Chemistry. 286: 14932-40. PMID 21343299 DOI: 10.1074/Jbc.M110.182170  0.507
2010 Suzuki T, Sakagami T, Young LR, Carey BC, Wood RE, Luisetti M, Wert SE, Rubin BK, Kevill K, Chalk C, Whitsett JA, Stevens C, Nogee LM, Campo I, Trapnell BC. Hereditary pulmonary alveolar proteinosis: pathogenesis, presentation, diagnosis, and therapy. American Journal of Respiratory and Critical Care Medicine. 182: 1292-304. PMID 20622029 DOI: 10.1164/Rccm.201002-0271Oc  0.464
2010 Carey B, Trapnell BC. The molecular basis of pulmonary alveolar proteinosis. Clinical Immunology (Orlando, Fla.). 135: 223-35. PMID 20338813 DOI: 10.1016/J.Clim.2010.02.017  0.525
2010 Sakagami T, Beck D, Uchida K, Suzuki T, Carey BC, Nakata K, Keller G, Wood RE, Wert SE, Ikegami M, Whitsett JA, Luisetti M, Davies S, Krischer JP, Brody A, et al. Patient-derived granulocyte/macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates. American Journal of Respiratory and Critical Care Medicine. 182: 49-61. PMID 20224064 DOI: 10.1164/Rccm.201001-0008Oc  0.509
2010 Uchida K, Carey B, Suzuki T, Nakata K, Trapnell B. Response: Granulocyte/macrophage colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy persons. Blood. 115: 431-3. PMID 20075172 DOI: 10.1182/Blood-2009-11-246041  0.47
2009 Sakagami T, Uchida K, Suzuki T, Carey BC, Wood RE, Wert SE, Whitsett JA, Trapnell BC, Luisetti M. Human GM-CSF autoantibodies and reproduction of pulmonary alveolar proteinosis. The New England Journal of Medicine. 361: 2679-81. PMID 20042763 DOI: 10.1056/Nejmc0904077  0.522
2009 Trapnell BC, Carey BC, Uchida K, Suzuki T. Pulmonary alveolar proteinosis, a primary immunodeficiency of impaired GM-CSF stimulation of macrophages. Current Opinion in Immunology. 21: 514-21. PMID 19796925 DOI: 10.1016/J.Coi.2009.09.004  0.532
2009 Uchida K, Nakata K, Suzuki T, Luisetti M, Watanabe M, Koch DE, Stevens CA, Beck DC, Denson LA, Carey BC, Keicho N, Krischer JP, Yamada Y, Trapnell BC. Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects. Blood. 113: 2547-56. PMID 19282464 DOI: 10.1182/blood-2009-05-155689  0.396
2008 Suzuki T, Sakagami T, Rubin BK, Nogee LM, Wood RE, Zimmerman SL, Smolarek T, Dishop MK, Wert SE, Whitsett JA, Grabowski G, Carey BC, Stevens C, van der Loo JC, Trapnell BC. Familial pulmonary alveolar proteinosis caused by mutations in CSF2RA. The Journal of Experimental Medicine. 205: 2703-10. PMID 18955570 DOI: 10.1084/Jem.20080990  0.458
2007 Uchida K, Beck DC, Yamamoto T, Berclaz PY, Abe S, Staudt MK, Carey BC, Filippi MD, Wert SE, Denson LA, Puchalski JT, Hauck DM, Trapnell BC. GM-CSF autoantibodies and neutrophil dysfunction in pulmonary alveolar proteinosis. The New England Journal of Medicine. 356: 567-79. PMID 17287477 DOI: 10.1056/Nejmoa062505  0.493
2007 Carey B, Staudt MK, Bonaminio D, Loo JCMvd, Trapnell BC. PU.1 redirects adenovirus to lysosomes in alveolar macrophages, uncoupling internalization from infection. Journal of Immunology. 178: 2440-2447. PMID 17277151 DOI: 10.4049/Jimmunol.178.4.2440  0.382
2007 Berclaz PY, Carey B, Fillipi MD, Wernke-Dollries K, Geraci N, Cush S, Richardson T, Kitzmiller J, O'connor M, Hermoyian C, Korfhagen T, Whitsett JA, Trapnell BC. GM-CSF regulates a PU.1-dependent transcriptional program determining the pulmonary response to LPS. American Journal of Respiratory Cell and Molecular Biology. 36: 114-21. PMID 16917076 DOI: 10.1165/Rcmb.2006-0174Oc  0.421
2005 Carey B, DeLay M, Strasser JE, Chalk C, Dudley-McClain K, Milligan GN, Brunner HI, Thornton S, Hirsch R. A soluble divalent class I MHC/IgG1 fusion protein activates CD8+ T cells in vivo. Clinical Immunology (Orlando, Fla.). 116: 65-76. PMID 15925833 DOI: 10.1016/J.Clim.2005.02.013  0.531
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