Year |
Citation |
Score |
2001 |
Wiradjaja F, Ooms LM, Whisstock JC, McColl B, Helfenbaum L, Sambrook JF, Gething MJ, Mitchell CA. The yeast inositol polyphosphate 5-phosphatase Inp54p localizes to the endoplasmic reticulum via a C-terminal hydrophobic anchoring tail: regulation of secretion from the endoplasmic reticulum. The Journal of Biological Chemistry. 276: 7643-53. PMID 11116155 DOI: 10.1074/jbc.M010471200 |
0.527 |
|
2000 |
Ooms LM, McColl BK, Wiradjaja F, Wijayaratnam AP, Gleeson P, Gething MJ, Sambrook J, Mitchell CA. The yeast inositol polyphosphate 5-phosphatases inp52p and inp53p translocate to actin patches following hyperosmotic stress: mechanism for regulating phosphatidylinositol 4,5-bisphosphate at plasma membrane invaginations. Molecular and Cellular Biology. 20: 9376-90. PMID 11094088 DOI: 10.1128/Mcb.20.24.9376-9390.2000 |
0.451 |
|
1997 |
Fourie AM, Hupp TR, Lane DP, Sang BC, Barbosa MS, Sambrook JF, Gething MJ. HSP70 binding sites in the tumor suppressor protein p53. The Journal of Biological Chemistry. 272: 19471-9. PMID 9235949 DOI: 10.1074/jbc.272.31.19471 |
0.453 |
|
1995 |
Gething MJ, Blond-Elguindi S, Buchner J, Fourie A, Knarr G, Modrow S, Nanu L, Segal M, Sambrook J. Binding sites for Hsp70 molecular chaperones in natural proteins. Cold Spring Harbor Symposia On Quantitative Biology. 60: 417-28. PMID 8824415 DOI: 10.1101/Sqb.1995.060.01.046 |
0.409 |
|
1995 |
Alizadeh H, Ma D, Berman M, Bellingham D, Comerford SA, Gething MJ, Sambrook JF, Niederkorn JY. Tissue-type plasminogen activator-induced invasion and metastasis of murine melanomas. Current Eye Research. 14: 449-58. PMID 7671626 DOI: 10.3109/02713689509003755 |
0.422 |
|
1994 |
Shohet RV, Spitzer S, Madison EL, Bassel-Duby R, Gething MJ, Sambrook JF. Inhibitor-resistant tissue-type plasminogen activator: an improved thrombolytic agent in vitro. Thrombosis and Haemostasis. 71: 124-8. PMID 8165630 |
0.396 |
|
1994 |
Ma D, Comerford S, Bellingham D, Sambrook J, Gething MJ, Alizadeh H, Anand R, Mellon J, Niederkorn JY. Capacity of simian virus 40 T antigen to induce self-tolerance but not immunological privilege in the anterior chamber of the eye. Transplantation. 57: 718-25. PMID 8140635 DOI: 10.1097/00007890-199403150-00014 |
0.415 |
|
1994 |
Zunino SJ, Simons LF, Sambrook JF, Gething MJ. Interleukin-1 promotes hyperglycemia and insulitis in mice normally resistant to streptozotocin-induced diabetes. The American Journal of Pathology. 145: 661-70. PMID 8080048 |
0.326 |
|
1994 |
Orth K, Willnow T, Herz J, Gething MJ, Sambrook J. Low density lipoprotein receptor-related protein is necessary for the internalization of both tissue-type plasminogen activator-inhibitor complexes and free tissue-type plasminogen activator. The Journal of Biological Chemistry. 269: 21117-22. PMID 8063731 |
0.408 |
|
1994 |
Anand R, Ma D, Alizadeh H, Comerford SA, Sambrook JF, Gething MJ, McLean IW, Niederkorn JY. Characterization of intraocular tumors arising in transgenic mice. Investigative Ophthalmology & Visual Science. 35: 3533-9. PMID 8056529 |
0.354 |
|
1994 |
Fourie AM, Sambrook JF, Gething MJ. Common and divergent peptide binding specificities of hsp70 molecular chaperones. The Journal of Biological Chemistry. 269: 30470-8. PMID 7982963 |
0.427 |
|
1994 |
Lacey SW, Naim HY, Magness RR, Gething MJ, Sambrook JF. Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level. The Biochemical Journal. 302: 929-35. PMID 7945222 DOI: 10.1042/Bj3020929 |
0.399 |
|
1994 |
Ma D, Alizadeh H, Comerford SA, Gething MJ, Sambrook JF, Anand R, Niederkorn JY. Rejection of intraocular tumors from transgenic mice by tumor-infiltrating lymphocytes. Current Eye Research. 13: 361-9. PMID 7914482 DOI: 10.3109/02713689409167300 |
0.357 |
|
1994 |
McMillan DR, Gething MJ, Sambrook J. The cellular response to unfolded proteins: intercompartmental signaling. Current Opinion in Biotechnology. 5: 540-5. PMID 7765470 DOI: 10.1016/0958-1669(94)90071-X |
0.503 |
|
1994 |
Naim HY, Jacob R, Naim H, Sambrook JF, Gething MJ. The pro region of human intestinal lactase-phlorizin hydrolase. The Journal of Biological Chemistry. 269: 26933-43. PMID 7523415 |
0.419 |
|
1994 |
Gething M, Blond-Elguindi S, Mori K, Sambrook JF. 5 Structure, Function, and Regulation of the Endoplasmic Reticulum Chaperone, BiP Cold Spring Harbor Monograph Archive. 26: 111-135. DOI: 10.1101/087969427.26.111 |
0.544 |
|
1993 |
Blond-Elguindi S, Fourie AM, Sambrook JF, Gething MJ. Peptide-dependent stimulation of the ATPase activity of the molecular chaperone BiP is the result of conversion of oligomers to active monomers. The Journal of Biological Chemistry. 268: 12730-5. PMID 8509407 |
0.398 |
|
1993 |
Kohno K, Normington K, Sambrook J, Gething MJ, Mori K. The promoter region of the yeast KAR2 (BiP) gene contains a regulatory domain that responds to the presence of unfolded proteins in the endoplasmic reticulum. Molecular and Cellular Biology. 13: 877-90. PMID 8423809 DOI: 10.1128/Mcb.13.2.877 |
0.594 |
|
1993 |
Mori K, Ma W, Gething MJ, Sambrook J. A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell. 74: 743-56. PMID 8358794 DOI: 10.1016/0092-8674(93)90521-Q |
0.611 |
|
1993 |
Madison EL, Kobe A, Gething MJ, Sambrook JF, Goldsmith EJ. Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser. Science (New York, N.Y.). 262: 419-21. PMID 8211162 DOI: 10.1126/Science.8211162 |
0.43 |
|
1993 |
Kittlesen DJ, Brown LR, Braciale VL, Sambrook JP, Gething MJ, Braciale TJ. Presentation of newly synthesized glycoproteins to CD4+ T lymphocytes. An analysis using influenza hemagglutinin transport mutants. The Journal of Experimental Medicine. 177: 1021-30. PMID 8096235 DOI: 10.1084/Jem.177.4.1021 |
0.498 |
|
1993 |
Blond-Elguindi S, Cwirla SE, Dower WJ, Lipshutz RJ, Sprang SR, Sambrook JF, Gething MJ. Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP. Cell. 75: 717-28. PMID 7902213 DOI: 10.1016/0092-8674(93)90492-9 |
0.406 |
|
1993 |
Sykes K, Gething MJ, Sambrook J. Proline isomerases function during heat shock. Proceedings of the National Academy of Sciences of the United States of America. 90: 5853-7. PMID 7685914 DOI: 10.1073/Pnas.90.12.5853 |
0.497 |
|
1992 |
Gething MJ, Sambrook J. Protein folding in the cell. Nature. 355: 33-45. PMID 1731198 DOI: 10.1038/355033A0 |
0.5 |
|
1992 |
Mori K, Sant A, Kohno K, Normington K, Gething MJ, Sambrook JF. A 22 bp cis-acting element is necessary and sufficient for the induction of the yeast KAR2 (BiP) gene by unfolded proteins. The Embo Journal. 11: 2583-93. PMID 1628622 DOI: 10.1002/J.1460-2075.1992.Tb05323.X |
0.596 |
|
1992 |
Bulleid NJ, Bassel-Duby RS, Freedman RB, Sambrook JF, Gething MJ. Cell-free synthesis of enzymically active tissue-type plasminogen activator. Protein folding determines the extent of N-linked glycosylation. The Biochemical Journal. 286: 275-80. PMID 1520279 |
0.507 |
|
1992 |
Orth K, Madison EL, Gething MJ, Sambrook JF, Herz J. Complexes of tissue-type plasminogen activator and its serpin inhibitor plasminogen-activator inhibitor type 1 are internalized by means of the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor. Proceedings of the National Academy of Sciences of the United States of America. 89: 7422-6. PMID 1502153 DOI: 10.1073/Pnas.89.16.7422 |
0.43 |
|
1992 |
Gallagher PJ, Henneberry JM, Sambrook JF, Gething MJ. Glycosylation requirements for intracellular transport and function of the hemagglutinin of influenza virus. Journal of Virology. 66: 7136-45. PMID 1331514 |
0.509 |
|
1992 |
Segal MS, Bye JM, Sambrook JF, Gething MJ. Disulfide bond formation during the folding of influenza virus hemagglutinin. The Journal of Cell Biology. 118: 227-44. PMID 1321156 DOI: 10.1083/jcb.118.2.227 |
0.517 |
|
1992 |
Bassel-Duby R, Jiang NY, Bittick T, Madison E, McGookey D, Orth K, Shohet R, Sambrook J, Gething MJ. Tyrosine 67 in the epidermal growth factor-like domain of tissue-type plasminogen activator is important for clearance by a specific hepatic receptor. The Journal of Biological Chemistry. 267: 9668-77. PMID 1315765 |
0.464 |
|
1991 |
Naim HY, Lacey SW, Sambrook JF, Gething MJ. Expression of a full-length cDNA coding for human intestinal lactase-phlorizin hydrolase reveals an uncleaved, enzymatically active, and transport-competent protein. The Journal of Biological Chemistry. 266: 12313-20. PMID 1905719 |
0.504 |
|
1990 |
Beck PJ, Gething MJ, Sambrook J, Lehrman MA. Complementing mutant alleles define three loci involved in mannosylation of Man5-GlcNAc2-P-P-dolichol in Chinese hamster ovary cells. Somatic Cell and Molecular Genetics. 16: 539-48. PMID 2267628 DOI: 10.1007/Bf01233094 |
0.474 |
|
1990 |
Beck PJ, Orlean P, Albright C, Robbins PW, Gething MJ, Sambrook JF. The Saccharomyces cerevisiae DPM1 gene encoding dolichol-phosphate-mannose synthase is able to complement a glycosylation-defective mammalian cell line. Molecular and Cellular Biology. 10: 4612-22. PMID 2201896 DOI: 10.1128/Mcb.10.9.4612 |
0.495 |
|
1990 |
Bird P, Gething MJ, Sambrook J. The functional efficiency of a mammalian signal peptide is directly related to its hydrophobicity. The Journal of Biological Chemistry. 265: 8420-5. PMID 2187865 |
0.439 |
|
1990 |
Roman LM, Simons LF, Hammer RE, Sambrook JF, Gething MJ. The expression of influenza virus hemagglutinin in the pancreatic beta cells of transgenic mice results in autoimmune diabetes. Cell. 61: 383-96. PMID 2185889 DOI: 10.1016/0092-8674(90)90521-F |
0.41 |
|
1990 |
Madison EL, Goldsmith EJ, Gething MJ, Sambrook JF, Gerard RD. Restoration of serine protease-inhibitor interaction by protein engineering. The Journal of Biological Chemistry. 265: 21423-6. PMID 2123870 |
0.453 |
|
1990 |
Madison EL, Goldsmith EJ, Gerard RD, Gething MJ, Sambrook JF, Bassel-Duby RS. Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1. Proceedings of the National Academy of Sciences of the United States of America. 87: 3530-3. PMID 2110366 DOI: 10.1073/Pnas.87.9.3530 |
0.459 |
|
1990 |
Gething MJ, Sambrook J. Transport and assembly processes in the endoplasmic reticulum. Seminars in Cell Biology. 1: 65-72. PMID 1983272 |
0.479 |
|
1989 |
Gething MJ, McCammon K, Sambrook J. Protein folding and intracellular transport: evaluation of conformational changes in nascent exocytotic proteins. Methods in Cell Biology. 32: 185-206. PMID 2691850 DOI: 10.1016/S0091-679X(08)61171-1 |
0.468 |
|
1989 |
Normington K, Kohno K, Kozutsumi Y, Gething MJ, Sambrook J. S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP. Cell. 57: 1223-36. PMID 2661019 DOI: 10.1016/0092-8674(89)90059-7 |
0.508 |
|
1989 |
Hearing J, Gething MJ, Sambrook J. Addition of truncated oligosaccharides to influenza virus hemagglutinin results in its temperature-conditional cell-surface expression. The Journal of Cell Biology. 108: 355-65. PMID 2645296 DOI: 10.1083/Jcb.108.2.355 |
0.483 |
|
1989 |
Gething MJ, Sambrook J. Protein folding and intracellular transport: studies on influenza virus haemagglutinin. Biochemical Society Symposium. 55: 155-66. PMID 2619766 |
0.497 |
|
1989 |
Sambrook J, Gething MJ. Protein structure. Chaperones, paperones. Nature. 342: 224-5. PMID 2572969 DOI: 10.1038/342224a0 |
0.427 |
|
1989 |
Kozutsumi Y, Normington K, Press E, Slaughter C, Sambrook J, Gething MJ. Identification of immunoglobulin heavy chain binding protein as glucose-regulated protein 78 on the basis of amino acid sequence, immunological cross-reactivity, and functional activity. Journal of Cell Science. Supplement. 11: 115-37. PMID 2559088 DOI: 10.1242/Jcs.1989.Supplement_11.10 |
0.514 |
|
1989 |
Hearing J, Hunter E, Rodgers L, Gething MJ, Sambrook J. Isolation of Chinese hamster ovary cell lines temperature conditional for the cell-surface expression of integral membrane glycoproteins. The Journal of Cell Biology. 108: 339-53. PMID 2537314 DOI: 10.1083/Jcb.108.2.339 |
0.506 |
|
1989 |
Madison EL, Goldsmith EJ, Gerard RD, Gething MJ, Sambrook JF. Serpin-resistant mutants of human tissue-type plasminogen activator. Nature. 339: 721-4. PMID 2500599 DOI: 10.1038/339721A0 |
0.445 |
|
1989 |
Boose JA, Kuismanen E, Gerard R, Sambrook J, Gething MJ. The single-chain form of tissue-type plasminogen activator has catalytic activity: studies with a mutant enzyme that lacks the cleavage site. Biochemistry. 28: 635-43. PMID 2496749 DOI: 10.1021/Bi00428A033 |
0.442 |
|
1989 |
Gething MJ, Mccammon K, Sambrook J. Chapter 7 Protein Folding and Intracellular Transport: Evaluation of Conformational Changes in Nascent Exocytotic Proteins Methods in Cell Biology. 32: 185-206. DOI: 10.1016/S0091-679X(08)61171-1 |
0.447 |
|
1989 |
Madison E, Goldsmith E, Gerard R, Gething M, Sambrook J. Mutants of human time-type plasminogen activator that are resistant to inhibition by the serpin PAI-1 Fibrinolysis. 3: 18. DOI: 10.1016/0268-9499(89)90117-3 |
0.469 |
|
1989 |
Madison E, Gething M, Sambrook J. The use of “loop-switch” mutations to probe fine structure(function relationships in the kringle II domain of t-PA Fibrinolysis. 3: 18. DOI: 10.1016/0268-9499(89)90116-1 |
0.468 |
|
1988 |
Kozutsumi Y, Segal M, Normington K, Gething MJ, Sambrook J. The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature. 332: 462-4. PMID 3352747 DOI: 10.1038/332462A0 |
0.518 |
|
1988 |
Gething MJ, Adler B, Boose JA, Gerard RD, Madison EL, McGookey D, Meidell RS, Roman LM, Sambrook J. Variants of human tissue-type plasminogen activator that lack specific structural domains of the heavy chain. The Embo Journal. 7: 2731-40. PMID 2846282 DOI: 10.1002/J.1460-2075.1988.Tb03127.X |
0.51 |
|
1988 |
Gallagher P, Henneberry J, Wilson I, Sambrook J, Gething MJ. Addition of carbohydrate side chains at novel sites on influenza virus hemagglutinin can modulate the folding, transport, and activity of the molecule. The Journal of Cell Biology. 107: 2059-73. PMID 2461945 DOI: 10.1083/Jcb.107.6.2059 |
0.534 |
|
1988 |
Gething MJ, Henneberry J, Sambrook J. Chapter 11 Fusion Activity of the Hemagglutinin of Influenza Virus Current Topics in Membranes and Transport. 32: 337-364. DOI: 10.1016/S0070-2161(08)60139-2 |
0.499 |
|
1987 |
Chao CC, Bird P, Gething MJ, Sambrook J. Posttranslational translocation of influenza virus hemagglutinin across microsomal membranes. Molecular and Cellular Biology. 7: 3842-5. PMID 3683400 DOI: 10.1128/MCB.7.10.3842 |
0.527 |
|
1987 |
Bird P, Gething MJ, Sambrook J. Translocation in yeast and mammalian cells: not all signal sequences are functionally equivalent. The Journal of Cell Biology. 105: 2905-14. PMID 3320059 |
0.484 |
|
1987 |
Braciale TJ, Morrison LA, Sweetser MT, Sambrook J, Gething MJ, Braciale VL. Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes. Immunological Reviews. 98: 95-114. PMID 2443444 DOI: 10.1111/J.1600-065X.1987.Tb00521.X |
0.324 |
|
1987 |
Braciale TJ, Braciale VL, Winkler M, Stroynowski I, Hood L, Sambrook J, Gething MJ. On the role of the transmembrane anchor sequence of influenza hemagglutinin in target cell recognition by class I MHC-restricted, hemagglutinin-specific cytolytic T lymphocytes. The Journal of Experimental Medicine. 166: 678-92. PMID 2442285 |
0.528 |
|
1986 |
Doyle C, Sambrook J, Gething MJ. Analysis of progressive deletions of the transmembrane and cytoplasmic domains of influenza hemagglutinin. The Journal of Cell Biology. 103: 1193-204. PMID 3771631 DOI: 10.1083/Jcb.103.4.1193 |
0.744 |
|
1986 |
Gething MJ, McCammon K, Sambrook J. Expression of wild-type and mutant forms of influenza hemagglutinin: the role of folding in intracellular transport. Cell. 46: 939-50. PMID 3757030 DOI: 10.1016/0092-8674(86)90076-0 |
0.554 |
|
1986 |
Gething MJ, Doms RW, York D, White J. Studies on the mechanism of membrane fusion: site-specific mutagenesis of the hemagglutinin of influenza virus. The Journal of Cell Biology. 102: 11-23. PMID 3753607 DOI: 10.1083/Jcb.102.1.11 |
0.36 |
|
1986 |
Sambrook J, Hanahan D, Rodgers L, Gething MJ. Expression of human tissue-type plasminogen activator from lytic viral vectors and in established cell lines. Molecular Biology & Medicine. 3: 459-81. PMID 3039288 |
0.481 |
|
1986 |
Roth MG, Doyle C, Sambrook J, Gething MJ. Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway. The Journal of Cell Biology. 102: 1271-83. PMID 3007532 DOI: 10.1083/Jcb.102.4.1271 |
0.748 |
|
1985 |
Doyle C, Roth MG, Sambrook J, Gething MJ. Mutations in the cytoplasmic domain of the influenza virus hemagglutinin affect different stages of intracellular transport. The Journal of Cell Biology. 100: 704-14. PMID 3972890 DOI: 10.1083/Jcb.100.3.704 |
0.746 |
|
1985 |
Sharma S, Rodgers L, Brandsma J, Gething MJ, Sambrook J. SV40 T antigen and the exocytotic pathway. The Embo Journal. 4: 1479-89. PMID 3849428 DOI: 10.1002/J.1460-2075.1985.Tb03806.X |
0.49 |
|
1985 |
Sambrook J, Rodgers L, White J, Gething MJ. Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin. The Embo Journal. 4: 91-103. PMID 2990897 DOI: 10.1002/J.1460-2075.1985.Tb02322.X |
0.509 |
|
1985 |
Gething MJ, Doyle C, Roth M, Sambrook J. Chapter 2 Mutational Analysis of the Structure and Function of the Influenza Virus Hemagglutinin Current Topics in Membranes and Transport. 23: 17-41. DOI: 10.1016/S0070-2161(08)60148-3 |
0.755 |
|
1984 |
Braciale TJ, Braciale VL, Henkel TJ, Sambrook J, Gething MJ. Cytotoxic T lymphocyte recognition of the influenza hemagglutinin gene product expressed by DNA-mediated gene transfer. The Journal of Experimental Medicine. 159: 341-54. PMID 6198429 |
0.473 |
|
1983 |
Roth MG, Compans RW, Giusti L, Davis AR, Nayak DP, Gething MJ, Sambrook J. Influenza virus hemagglutinin expression is polarized in cells infected with recombinant SV40 viruses carrying cloned hemagglutinin DNA. Cell. 33: 435-43. PMID 6305510 DOI: 10.1016/0092-8674(83)90425-7 |
0.503 |
|
1982 |
Gething MJ, Sambrook J. Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the protein. Nature. 300: 598-603. PMID 7144911 DOI: 10.1038/300598A0 |
0.598 |
|
1982 |
White J, Helenius A, Gething MJ. Haemagglutinin of influenza virus expressed from a cloned gene promotes membrane fusion. Nature. 300: 658-9. PMID 6815542 DOI: 10.1038/300658A0 |
0.31 |
|
1981 |
Gething MJ, Sambrook J. Cell-surface expression of influenza haemagglutinin from a cloned DNA copy of the RNA gene. Nature. 293: 620-5. PMID 6270568 DOI: 10.1038/293620A0 |
0.491 |
|
1980 |
Koszinowski UH, Allen H, Gething MJ, Waterfield MD, Klenk HD. Recognition of viral glycoproteins by influenza A-specific cross-reactive cytolytic T lymphocytes. The Journal of Experimental Medicine. 151: 945-58. PMID 6154763 DOI: 10.1084/Jem.151.4.945 |
0.32 |
|
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