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Spencer John Williams, Ph.D. - Publications

Affiliations: 
2002- Chemistry University of Melbourne, Parkville, Victoria, Australia 
Area:
Carbohydrates
Website:
http://www2.chemistry.unimelb.edu.au/staff/sjwill/research/

156 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Li J, Mui JW, da Silva BM, Pires DEV, Ascher DB, Madiedo Soler N, Goddard-Borger ED, Williams SJ. A Broad-Spectrum α-Glucosidase of Glycoside Hydrolase Family 13 from Marinovum sp., a Member of the Roseobacter Clade. Applied Biochemistry and Biotechnology. PMID 38180643 DOI: 10.1007/s12010-023-04820-3  0.648
2023 Li J, Sharma M, Meek R, Alhifthi A, Armstrong Z, Soler NM, Lee M, Goddard-Borger ED, Blaza JN, Davies GJ, Williams SJ. Correction: Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from . Chemical Science. 15: 778-779. PMID 38179515 DOI: 10.1039/d3sc90238b  0.582
2023 Kaur A, Pickles IB, Sharma M, Madeido Soler N, Scott NE, Pidot SJ, Goddard-Borger ED, Davies GJ, Williams SJ. Widespread Family of NAD-Dependent Sulfoquinovosidases at the Gateway to Sulfoquinovose Catabolism. Journal of the American Chemical Society. PMID 38100472 DOI: 10.1021/jacs.3c11126  0.62
2023 Li J, Sharma M, Meek R, Alhifthi A, Armstrong Z, Soler NM, Lee M, Goddard-Borger ED, Blaza JN, Davies GJ, Williams SJ. Molecular basis of sulfolactate synthesis by sulfolactaldehyde dehydrogenase from . Chemical Science. 14: 11429-11440. PMID 37886098 DOI: 10.1039/d3sc01594g  0.63
2023 Sharma M, Kaur A, Madiedo Soler N, Lingford JP, Epa R, Goddard-Borger ED, Davies GJ, Williams SJ. Defining the molecular architecture, metal dependence, and distribution of metal-dependent class II sulfofructose-1-phosphate aldolases. The Journal of Biological Chemistry. 299: 105338. PMID 37838169 DOI: 10.1016/j.jbc.2023.105338  0.618
2023 Al-Jourani O, Benedict ST, Ross J, Layton AJ, van der Peet P, Marando VM, Bailey NP, Heunis T, Manion J, Mensitieri F, Franklin A, Abellon-Ruiz J, Oram SL, Parsons L, Cartmell A, ... ... Williams SJ, et al. Identification of D-arabinan-degrading enzymes in mycobacteria. Nature Communications. 14: 2233. PMID 37076525 DOI: 10.1038/s41467-023-37839-5  0.672
2023 Kaur A, Scott NE, Herisse M, Goddard-Borger ED, Pidot S, Williams SJ. Identification of levoglucosan degradation pathways in bacteria and sequence similarity network analysis. Archives of Microbiology. 205: 155. PMID 37000297 DOI: 10.1007/s00203-023-03506-y  0.639
2023 Arumapperuma T, Li J, Hornung B, Madiedo Soler N, Goddard-Borger ED, Terrapon N, Williams SJ. A subfamily classification to choreograph the diverse activities within Glycoside Hydrolase family 31 (GH31). The Journal of Biological Chemistry. 103038. PMID 36806678 DOI: 10.1016/j.jbc.2023.103038  0.624
2023 Snow AJD, Sharma M, Abayakoon P, Williams SJ, Blaza JN, Davies GJ. Structure and mechanism of sulfofructose transaldolase, a key enzyme in sulfoquinovose metabolism. Structure (London, England : 1993). 31: 244-252.e4. PMID 36805128 DOI: 10.1016/j.str.2023.01.010  0.805
2022 Snow AJD, Sharma M, Lingford JP, Zhang Y, Mui JW, Epa R, Goddard-Borger ED, Williams SJ, Davies GJ. The sulfoquinovosyl glycerol binding protein SmoF binds and accommodates plant sulfolipids. Current Research in Structural Biology. 4: 51-58. PMID 35341160 DOI: 10.1016/j.crstbi.2022.03.001  0.609
2022 Sharma M, Lingford JP, Petricevic M, Snow AJD, Zhang Y, Järvå MA, Mui JW, Scott NE, Saunders EC, Mao R, Epa R, da Silva BM, Pires DEV, Ascher DB, McConville MJ, ... ... Williams SJ, et al. Oxidative desulfurization pathway for complete catabolism of sulfoquinovose by bacteria. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35074914 DOI: 10.1073/pnas.2116022119  0.633
2021 Sharma M, Abayakoon P, Epa R, Jin Y, Lingford JP, Shimada T, Nakano M, Mui JW, Ishihama A, Goddard-Borger ED, Davies GJ, Williams SJ. Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis. Acs Central Science. 7: 476-487. PMID 33791429 DOI: 10.1021/acscentsci.0c01285  0.796
2020 Burugupalli S, Almeida CF, Smith DGM, Shah S, Patel O, Rossjohn J, Uldrich AP, Godfrey DI, Williams SJ. α-Glucuronosyl and α-glucosyl diacylglycerides, natural killer T cell-activating lipids from bacteria and fungi. Chemical Science. 11: 2161-2168. PMID 34123306 DOI: 10.1039/c9sc05248h  0.575
2020 Williams SJ, Goddard-Borger ED. α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19. Biochemical Society Transactions. PMID 32510142 DOI: 10.1042/Bst20200505  0.624
2020 Sobala LF, Speciale G, Zhu S, Raich L, Sannikova N, Thompson AJ, Hakki Z, Lu D, Shamsi Kazem Abadi S, Lewis AR, Rojas-Cervellera V, Bernardo-Seisdedos G, Zhang Y, Millet O, Jiménez-Barbero J, ... ... Williams SJ, et al. An Epoxide Intermediate in Glycosidase Catalysis. Acs Central Science. 6: 760-770. PMID 32490192 DOI: 10.1021/Acscentsci.0C00111  0.771
2020 Li J, Epa R, Scott NE, Skoneczny D, Sharma M, Snow AJD, Lingford JP, Goddard-Borger ED, Davies GJ, McConville MJ, Williams SJ. A sulfoglycolytic Entner-Doudoroff pathway in bv. SRDI565. Applied and Environmental Microbiology. PMID 32444469 DOI: 10.1128/Aem.00750-20  0.658
2020 Smith DGM, Hosono Y, Nagata M, Yamasaki S, Williams SJ. Design of potent Mincle signalling agonists based on an alkyl β-glucoside template. Chemical Communications (Cambridge, England). PMID 32182321 DOI: 10.1039/D0Cc00670J  0.306
2020 Zhang Y, Mui JW, Arumaperuma T, Lingford JP, Goddard-Borger ED, White JM, Williams SJ. Concise synthesis of sulfoquinovose and sulfoquinovosyl diacylglycerides, and development of a fluorogenic substrate for sulfoquinovosidases. Organic & Biomolecular Chemistry. PMID 31894821 DOI: 10.1039/C9Ob02540E  0.676
2020 Burugupalli S, Almeida CF, Smith DGM, Shah S, Patel O, Rossjohn J, Uldrich AP, Godfrey DI, Williams SJ. α-Glucuronosyl and α-glucosyl diacylglycerides, natural killer T cell-activating lipids from bacteria and fungi Chemical Science. 11: 2161-2168. DOI: 10.1039/C9Sc05248H  0.596
2020 Sharma M, Abayakoon P, Lingford JP, Epa R, John A, Jin Y, Goddard-Borger ED, Davies GJ, Williams SJ. Dynamic Structural Changes Accompany the Production of Dihydroxypropanesulfonate by Sulfolactaldehyde Reductase Acs Catalysis. 10: 2826-2836. DOI: 10.1021/Acscatal.9B04427  0.799
2019 Rovira C, Males A, Davies GJ, Williams SJ. Mannosidase mechanism: at the intersection of conformation and catalysis. Current Opinion in Structural Biology. 62: 79-92. PMID 31891872 DOI: 10.1016/J.Sbi.2019.11.008  0.333
2019 Dumont L, Richardson MB, van der Peet P, Marapana DS, Triglia T, Dixon MWA, Cowman AF, Williams SJ, Tilley L, McConville MJ, Cobbold SA. The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum. Mbio. 10. PMID 31822583 DOI: 10.1128/Mbio.02060-19  0.637
2019 Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, et al. Author Correction: A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nature Microbiology. PMID 31541200 DOI: 10.1038/S41564-019-0584-5  0.729
2019 Sernee MF, Ralton JE, Nero TL, Sobala LF, Kloehn J, Vieira-Lara MA, Cobbold SA, Stanton L, Pires DEV, Hanssen E, Males A, Ward T, Bastidas LM, van der Peet PL, Parker MW, ... ... Williams SJ, et al. A Family of Dual-Activity Glycosyltransferase-Phosphorylases Mediates Mannogen Turnover and Virulence in Leishmania Parasites. Cell Host & Microbe. 26: 385-399.e9. PMID 31513773 DOI: 10.1016/J.Chom.2019.08.009  0.333
2019 Males A, Speciale G, Williams SJ, Davies GJ. Distortion of mannoimidazole supports a B boat transition state for the family GH125 α-1,6-mannosidase from Clostridium perfringens. Organic & Biomolecular Chemistry. PMID 31407758 DOI: 10.1039/C9Ob01161G  0.748
2019 van der Peet PL, Gunawan C, Watanabe M, Yamasaki S, Williams SJ. Correction to "Synthetic β-1,2-Mannosyloxymannitol Glycolipid from the Fungus Malassezia pachydermatis Signals through Human Mincle". The Journal of Organic Chemistry. PMID 31244087 DOI: 10.1021/Acs.Joc.9B01609  0.649
2019 van der Peet PL, Gunawan C, Watanabe M, Yamasaki S, Williams SJ. A synthetic β-1,2-mannosyloxymannitol glycolipid from the fungus Malassezia pachydermatis signals through human Mincle. The Journal of Organic Chemistry. PMID 31046282 DOI: 10.1021/Acs.Joc.9B00544  0.656
2019 Abayakoon P, Epa R, Petricevic M, Bengt C, Mui JW, van der Peet PL, Zhang Y, Lingford JP, White JM, Goddard-Borger ED, Williams SJ. Comprehensive synthesis of substrates, intermediates and products of the sulfoglycolytic Embden-Meyerhoff-Parnas pathway. The Journal of Organic Chemistry. PMID 30742766 DOI: 10.1021/Acs.Joc.9B00055  0.786
2019 van der Peet PL, Sandanayake S, Jarrott B, Williams SJ. Discovery of N-Aryloxypropylbenzylamines as Voltage-gated Sodium Channel NaV1.2 subtype Selective Inhibitors. Chemmedchem. PMID 30676691 DOI: 10.1002/Cmdc.201800781  0.762
2018 Cartmell A, Muñoz-Muñoz J, Briggs JA, Ndeh DA, Lowe EC, Baslé A, Terrapon N, Stott K, Heunis T, Gray J, Yu L, Dupree P, Fernandes PZ, Shah S, Williams SJ, et al. A surface endogalactanase in Bacteroides thetaiotaomicron confers keystone status for arabinogalactan degradation. Nature Microbiology. PMID 30349080 DOI: 10.1038/S41564-018-0258-8  0.782
2018 Abayakoon P, Jin Y, Lingford JP, Petricevic M, John A, Ryan E, Wai-Ying Mui J, Pires DEV, Ascher DB, Davies GJ, Goddard-Borger ED, Williams SJ. Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases. Acs Central Science. 4: 1266-1273. PMID 30276262 DOI: 10.1021/Acscentsci.8B00453  0.795
2018 van der Peet PL, Gunawan C, Abdul-Ridha A, Ma S, Scott DJ, Gundlach AL, Bathgate RAD, White JM, Williams SJ. Gram scale preparation of clozapine -oxide (CNO), a synthetic small molecule actuator for muscarinic acetylcholine DREADDs. Methodsx. 5: 257-267. PMID 30038895 DOI: 10.1016/J.Mex.2018.03.003  0.64
2018 Schröder SP, Kallemeijn WW, Debets MF, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS. Spiro-epoxyglycosides as activity-based probes for glycoside hydrolase family 99 endomannosidase/endomannanase. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29797675 DOI: 10.1002/Chem.201801902  0.393
2018 Thompson AJ, Spears RJ, Zhu Y, Suits MDL, Williams SJ, Gilbert HJ, Davies GJ. Bacteroides thetaiotaomicron generates diverse α-mannosidase activities through subtle evolution of a distal substrate-binding motif. Acta Crystallographica. Section D, Structural Biology. 74: 394-404. PMID 29717710 DOI: 10.1107/S2059798318002942  0.38
2018 Abayakoon P, Lingford JP, Jin Y, Bengt C, Davies GJ, Yao S, Goddard-Borger ED, Williams SJ. Discovery and characterization of a sulfoquinovose mutarotase using kinetic analysis at equilibrium by exchange spectroscopy. The Biochemical Journal. PMID 29535276 DOI: 10.1042/Bcj20170947  0.787
2018 Fernandes PZ, Petricevic M, Sobala L, Davies GJ, Williams SJ. Exploration of strategies for mechanism-based inhibitor design for family GH99 endo-α-1,2-mannanases. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29508463 DOI: 10.1002/Chem.201800435  0.379
2018 Abbott W, Alber O, Bayer E, Berrin J, Boraston A, Brumer H, Brzezinski R, Clarke A, Cobucci-Ponzano B, Cockburn D, Coutinho P, Czjzek M, Dassa B, Davies GJ, Eijsink V, ... ... Williams S, et al. Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes Glycobiology. 28: 3-8. PMID 29040563 DOI: 10.1093/Glycob/Cwx089  0.792
2017 Bellmaine SF, Ovchinnikov DA, Manallack DT, Cuddy CE, Elefanty AG, Stanley EG, Wolvetang EJ, Williams SJ, Pera M. Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells. Elife. 6. PMID 28884684 DOI: 10.7554/Elife.24502  0.761
2017 Burugupalli S, Richardson MB, Williams SJ. Total synthesis and mass spectrometric analysis of a Mycobacterium tuberculosis phosphatidylglycerol featuring a two-step synthesis of (R)-tuberculostearic acid. Organic & Biomolecular Chemistry. PMID 28831486 DOI: 10.1039/C7Ob01786C  0.609
2017 Belz T, Jin Y, Coines J, Rovira C, Davies GJ, Williams SJ. An atypical interaction explains the high-affinity of a non-hydrolyzable S-linked 1,6-α-mannanase inhibitor. Chemical Communications (Cambridge, England). PMID 28766587 DOI: 10.1039/C7Cc04977C  0.316
2017 Males A, Raich L, Williams SJ, Rovira C, Davies GJ. Conformational analysis of the mannosidase inhibitor kifunensine: a quantum mechanical and structural approach. Chembiochem : a European Journal of Chemical Biology. PMID 28493500 DOI: 10.1002/Cbic.201700166  0.342
2017 Osburn S, Speciale G, Williams SJ, O'Hair RAJ. Gas-Phase Intercluster Thiyl-Radical Induced C-H Bond Homolysis Selectively Forms Sugar C2-Radical Cations of Methyl D-Glucopyranoside: Isotopic Labeling Studies and Cleavage Reactions. Journal of the American Society For Mass Spectrometry. PMID 28474266 DOI: 10.1007/S13361-017-1667-2  0.735
2017 Temple MJ, Cuskin F, Baslé A, Hickey N, Speciale G, Williams SJ, Gilbert HJ, Lowe EC. A Bacteroidetes locus dedicated to fungal 1,6-β-glucan degradation: unique substrate conformation drives specificity of the key endo-1,6-β-glucanase. The Journal of Biological Chemistry. PMID 28461332 DOI: 10.1074/Jbc.M117.787606  0.736
2017 Kuribara T, Hirano M, Speciale G, Williams SJ, Ito Y, Totani K. Selective Manipulation of Discrete Mannosidase Activities in the Endoplasmic Reticulum by Using Reciprocally Selective Inhibitors. Chembiochem : a European Journal of Chemical Biology. PMID 28371030 DOI: 10.1002/Cbic.201700081  0.754
2017 Goddard-Borger ED, Williams SJ. Sulfoquinovose in the biosphere: occurrence, metabolism and functions. The Biochemical Journal. 474: 827-849. PMID 28219973 DOI: 10.1042/Bcj20160508  0.663
2017 Richardson MB, Smith DG, Williams SJ. Quantitation in the regioselectivity of acylation of glycosyl diglycerides: total synthesis of a Streptococcus pneumoniae α-glucosyl diglyceride. Chemical Communications (Cambridge, England). PMID 28054047 DOI: 10.1039/C6Cc09584D  0.637
2017 Bellmaine SF, Ovchinnikov DA, Manallack DT, Cuddy CE, Elefanty AG, Stanley EG, Wolvetang EJ, Williams SJ, Pera M. Author response: Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells Elife. DOI: 10.7554/Elife.24502.019  0.751
2017 Kuribara T, Hirano M, Speciale G, Williams SJ, Ito Y, Totani K. Inside Cover: Selective Manipulation of Discrete Mannosidase Activities in the Endoplasmic Reticulum by Using Reciprocally Selective Inhibitors (ChemBioChem 11/2017) Chembiochem. 18: 966-966. DOI: 10.1002/Cbic.201700243  0.72
2016 Jin Y, Petricevic M, John A, Raich L, Jenkins H, Portela De Souza L, Cuskin F, Gilbert HJ, Rovira C, Goddard-Borger ED, Williams SJ, Davies GJ. A β-Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism. Acs Central Science. 2: 896-903. PMID 28058278 DOI: 10.1021/Acscentsci.6B00232  0.672
2016 Alonso-Gil S, Males A, Fernandes P, Williams SJ, Davies GJ, Rovira C. Computational design-of-experiment unveils the conformational reaction coordinate of GH125 α-mannosidases. Journal of the American Chemical Society. PMID 28026180 DOI: 10.1021/Jacs.6B11247  0.375
2016 Petricevic M, Sobala LF, Fernandes P, Raich L, Thompson AJ, Bernardo-Seisdedos G, Millet O, Zhu S, Sollogoub M, Jimenez-Barbero J, Rovira C, Davies GJ, Williams SJ. Contribution of shape and charge to the inhibition of a family GH99 endo-α-1,2-mannanase. Journal of the American Chemical Society. PMID 27992199 DOI: 10.1021/Jacs.6B10075  0.371
2016 Speciale G, Farren-Dai M, Shidmoossavee FS, Williams SJ, Bennet AJ. C2-Oxyanion neighboring group participation: Transition state structure for the hydroxide-promoted hydrolysis of 4-nitrophenyl α-D-mannopyranoside. Journal of the American Chemical Society. PMID 27723312 DOI: 10.1021/Jacs.6B07935  0.737
2016 van der Peet PL, Nagata M, Shah S, White JM, Yamasaki S, Williams SJ. Lipid structure influences the ability of glucose monocorynomycolate to signal through Mincle. Organic & Biomolecular Chemistry. 14: 9267-9277. PMID 27714279 DOI: 10.1039/C6Ob01781A  0.616
2016 Roth C, Petricevic M, John A, Goddard-Borger ED, Davies GJ, Williams SJ. Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-β-galactosaminidase that uses neighbouring group participation. Chemical Communications (Cambridge, England). PMID 27546776 DOI: 10.1039/C6Cc04649E  0.674
2016 Shah S, Nagata M, Yamasaki S, Williams SJ. Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle. Chemical Communications (Cambridge, England). PMID 27533919 DOI: 10.1039/C6Cc05631H  0.621
2016 Belz T, Williams SJ. A building block approach to the synthesis of a family of S-linked α-1,6-oligomannosides. Carbohydrate Research. PMID 27129668 DOI: 10.1016/J.Carres.2016.04.015  0.301
2016 Charoenwattanasatien R, Pengthaisong S, Breen I, Mutoh R, Sansenya S, Hua Y, Tankrathok A, Wu L, Songsiriritthigul C, Tanaka H, Williams SJ, Davies GJ, Kurisu G, Ketudat Cairns JR. Bacterial β-glucosidase reveals the structural and functional basis of genetic defects in human glucocerebrosidase 2 (GBA2). Acs Chemical Biology. PMID 27115290 DOI: 10.1021/Acschembio.6B00192  0.333
2016 Speciale G, Jin Y, Davies GJ, Williams SJ, Goddard-Borger ED. YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids. Nature Chemical Biology. PMID 26878550 DOI: 10.1038/Nchembio.2023  0.785
2016 Davies GJ, Williams SJ. Carbohydrate-active enzymes: sequences, shapes, contortions and cells. Biochemical Society Transactions. 44: 79-87. PMID 26862192 DOI: 10.1042/Bst20150186  0.371
2016 Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Corrigendum: Evidence for a Boat Conformation at the Transition State of GH76 α-1,6-Mannanases-Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism. Angewandte Chemie (International Ed. in English). 55: 1949. PMID 26836331 DOI: 10.1002/Anie.201511540  0.804
2016 Roth C, Petricevic M, John A, Goddard-Borger ED, Davies GJ, Williams SJ. Structural and mechanistic insights into a Bacteroides vulgatus retaining N-acetyl-β-galactosaminidase that uses neighbouring group participation Acta Crystallographica Section a Foundations and Advances. 72: s221-s221. DOI: 10.1107/S2053273316096637  0.643
2015 Burugupalli S, Shah S, van der Peet PL, Arora S, White JM, Williams SJ. Investigation of benzoyloximes as benzoylating reagents: benzoyl-Oxyma as a selective benzoylating reagent. Organic & Biomolecular Chemistry. PMID 26531176 DOI: 10.1039/C5Ob02092A  0.596
2015 Richardson MB, Torigoe S, Yamasaki S, Williams SJ. Mycobacterium tuberculosis β-gentiobiosyl diacylglycerides signal through the pattern recognition receptor Mincle: total synthesis and structure activity relationships. Chemical Communications (Cambridge, England). PMID 26310657 DOI: 10.1039/C5Cc04773K  0.63
2015 Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism. Angewandte Chemie (International Ed. in English). 54: 5378-82. PMID 25772148 DOI: 10.1002/Anie.201410502  0.804
2015 Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron EA, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, ... ... Williams SJ, et al. Corrigendum: Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 520: 388. PMID 25739504 DOI: 10.1038/Nature14334  0.776
2015 van der Peet PL, Gunawan C, Torigoe S, Yamasaki S, Williams SJ. Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle. Chemical Communications (Cambridge, England). 51: 5100-3. PMID 25714652 DOI: 10.1039/C5Cc00085H  0.658
2015 Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron EA, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, ... ... Williams SJ, et al. Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism. Nature. 517: 165-9. PMID 25567280 DOI: 10.1038/Nature13995  0.786
2015 Hakki Z, Thompson AJ, Bellmaine S, Speciale G, Davies GJ, Williams SJ. Structural and kinetic dissection of the endo-α-1,2-mannanase activity of bacterial GH99 glycoside hydrolases from Bacteroides spp. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 1966-77. PMID 25487964 DOI: 10.1002/Chem.201405539  0.799
2015 Tankrathok A, Iglesias-Fernández J, Williams RJ, Pengthaisong S, Baiya S, Hakki Z, Robinson RC, Hrmova M, Rovira C, Williams SJ, Ketudat Cairns JR. A Single Glycosidase Harnesses Different Pyranoside Ring Transition State Conformations for Hydrolysis of Mannosides and Glucosides Acs Catalysis. 5: 6041-6051. DOI: 10.1021/Acscatal.5B01547  0.532
2014 Holien JK, Gazina EV, Elliott RW, Jarrott B, Cameron CE, Williams SJ, Parker MW, Petrou S. Computational Analysis of Amiloride Analogue Inhibitors of Coxsackievirus B3 RNA Polymerase. Journal of Proteomics & Bioinformatics. 004. PMID 26491236 DOI: 10.4172/Jpb.S9-004  0.326
2014 Shah S, White JM, Williams SJ. Total syntheses of cis-cyclopropane fatty acids: dihydromalvalic acid, dihydrosterculic acid, lactobacillic acid, and 9,10-methylenehexadecanoic acid. Organic & Biomolecular Chemistry. 12: 9427-38. PMID 25321346 DOI: 10.1039/C4Ob01863J  0.571
2014 Speciale G, Thompson AJ, Davies GJ, Williams SJ. Dissecting conformational contributions to glycosidase catalysis and inhibition. Current Opinion in Structural Biology. 28: 1-13. PMID 25016573 DOI: 10.1016/J.Sbi.2014.06.003  0.753
2014 Richardson MB, Williams SJ. MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns. Frontiers in Immunology. 5: 288. PMID 25002863 DOI: 10.3389/Fimmu.2014.00288  0.591
2014 Ash BL, Quach T, Williams SJ, Lawrence AJ, Djouma E. Galanin-3 receptor antagonism by SNAP 37889 reduces motivation to self-administer alcohol and attenuates cue-induced reinstatement of alcohol-seeking in iP rats. Journal of Pharmacological Sciences. 125: 211-6. PMID 24881957 DOI: 10.1254/Jphs.13221Fp  0.507
2014 Williams SJ, Denehy E, Krenske EH. Experimental and theoretical insights into the mechanisms of sulfate and sulfamate ester hydrolysis and the end products of type I sulfatase inactivation by aryl sulfamates. The Journal of Organic Chemistry. 79: 1995-2005. PMID 24555731 DOI: 10.1021/Jo4026513  0.349
2014 Williams RJ, Iglesias-Fernández J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ. Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate. Angewandte Chemie (International Ed. in English). 53: 1087-91. PMID 24339341 DOI: 10.1002/Anie.201308334  0.545
2013 Williams SJ, Zammit SC, Cox AJ, Shackleford DM, Morizzi J, Zhang Y, Powell AK, Gilbert RE, Krum H, Kelly DJ. 3',4'-Bis-difluoromethoxycinnamoylanthranilate (FT061): an orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathy. Bioorganic & Medicinal Chemistry Letters. 23: 6868-73. PMID 24169234 DOI: 10.1016/J.Bmcl.2013.09.100  0.542
2013 Richardson MB, Williams SJ. A practical synthesis of long-chain iso-fatty acids (iso-C12-C19) and related natural products. Beilstein Journal of Organic Chemistry. 9: 1807-12. PMID 24062846 DOI: 10.3762/Bjoc.9.210  0.593
2013 Lim NR, Thomas CJ, Silva LS, Yeap YY, Yap S, Bell JR, Delbridge LM, Bogoyevitch MA, Woodman OL, Williams SJ, May CN, Ng DC. Cardioprotective 3',4'-dihydroxyflavonol attenuation of JNK and p38(MAPK) signalling involves CaMKII inhibition. The Biochemical Journal. 456: 149-61. PMID 24032640 DOI: 10.1042/Bj20121538  0.531
2013 van der Peet PL, Connell TU, Gunawan C, White JM, Donnelly PS, Williams SJ. A click chemistry approach to 5,5'-disubstituted-3,3'-bisisoxazoles from dichloroglyoxime and alkynes: luminescent organometallic iridium and rhenium bisisoxazole complexes. The Journal of Organic Chemistry. 78: 7298-304. PMID 23777255 DOI: 10.1021/Jo4008755  0.652
2013 Connell TU, Sandanayake S, Khairallah GN, White JM, O'Hair RA, Donnelly PS, Williams SJ. Halide-ion-templated Ag8Cu6 rhombic dodecahedrons: synthesis, structure and reactivity of [Ag8Cu6(C≡CtBu)12X]BF4 (X = Cl, Br). Dalton Transactions (Cambridge, England : 2003). 42: 4903-7. PMID 23377186 DOI: 10.1039/C3Dt33027C  0.77
2013 Cao B, Chen X, Yamaryo-Botte Y, Richardson MB, Martin KL, Khairallah GN, Rupasinghe TW, O'Flaherty RM, O'Hair RA, Ralton JE, Crellin PK, Coppel RL, McConville MJ, Williams SJ. Synthesis, structural elucidation, and biochemical analysis of immunoactive glucuronosyl diacylglycerides of mycobacteria and corynebacteria. The Journal of Organic Chemistry. 78: 2175-90. PMID 23343519 DOI: 10.1021/Jo302508E  0.619
2013 Zhang Y, Elsik M, Edgley AJ, Cox AJ, Kompa AR, Wang B, Tan CY, Khong FL, Stapleton DI, Zammit S, Williams SJ, Gilbert RE, Krum H, Kelly DJ. A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction. International Journal of Cardiology. 168: 1174-85. PMID 23219315 DOI: 10.1016/J.Ijcard.2012.11.067  0.531
2012 Gilbert RE, Zhang Y, Williams SJ, Zammit SC, Stapleton DI, Cox AJ, Krum H, Langham R, Kelly DJ. A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat. Plos One. 7: e47160. PMID 23071743 DOI: 10.1371/Journal.Pone.0047160  0.544
2012 Thompson AJ, Dabin J, Iglesias-Fernández J, Ardèvol A, Dinev Z, Williams SJ, Bande O, Siriwardena A, Moreland C, Hu TC, Smith DK, Gilbert HJ, Rovira C, Davies GJ. The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach. Angewandte Chemie (International Ed. in English). 51: 10997-1001. PMID 23012075 DOI: 10.1002/Anie.201205338  0.802
2012 Heskes AM, Goodger JQ, Tsegay S, Quach T, Williams SJ, Woodrow IE. Localization of oleuropeyl glucose esters and a flavanone to secretory cavities of Myrtaceae. Plos One. 7: e40856. PMID 22911712 DOI: 10.1371/Journal.Pone.0040856  0.766
2012 Tsegay S, Williams RJ, Williams SJ. Synthesis of glycosyl fluorides from thio-, seleno-, and telluroglycosides and glycosyl sulfoxides using aminodifluorosulfinium tetrafluoroborates. Carbohydrate Research. 357: 16-22. PMID 22682311 DOI: 10.1016/J.Carres.2012.04.016  0.769
2012 Tan SM, Zhang Y, Wang B, Tan CY, Zammit SC, Williams SJ, Krum H, Kelly DJ. FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy. Clinical and Experimental Pharmacology & Physiology. 39: 650-6. PMID 22612418 DOI: 10.1111/J.1440-1681.2012.05726.X  0.537
2012 Zhang Y, Edgley AJ, Cox AJ, Powell AK, Wang B, Kompa AR, Stapleton DI, Zammit SC, Williams SJ, Krum H, Gilbert RE, Kelly DJ. FT011, a new anti-fibrotic drug, attenuates fibrosis and chronic heart failure in experimental diabetic cardiomyopathy. European Journal of Heart Failure. 14: 549-62. PMID 22417655 DOI: 10.1093/Eurjhf/Hfs011  0.526
2012 van der Peet P, Ralton JE, McConville MJ, Williams SJ. Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library. Plos One. 7: e32642. PMID 22393429 DOI: 10.1371/Journal.Pone.0032642  0.365
2012 Tilley AJ, Zanatta SD, Qin CX, Kim IK, Seok YM, Stewart A, Woodman OL, Williams SJ. 2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition. Bioorganic & Medicinal Chemistry. 20: 2353-61. PMID 22377671 DOI: 10.1016/J.Bmc.2012.02.008  0.711
2012 Thompson AJ, Williams RJ, Hakki Z, Alonzi DS, Wennekes T, Gloster TM, Songsrirote K, Thomas-Oates JE, Wrodnigg TM, Spreitz J, Stütz AE, Butters TD, Williams SJ, Davies GJ. Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase. Proceedings of the National Academy of Sciences of the United States of America. 109: 781-6. PMID 22219371 DOI: 10.1073/Pnas.1111482109  0.552
2012 Quach T, Tsegay S, Thompson AJ, Kukushkin NV, Alonzi DS, Butters TD, Davies GJ, Williams SJ. Fleetamine (3-O-α-d-glucopyranosyl-swainsonine): The synthesis of a hypothetical inhibitor of endo-α-mannosidase Tetrahedron Asymmetry. 23: 992-997. DOI: 10.1016/J.Tetasy.2012.06.011  0.801
2012 Thompson AJ, Dabin J, Iglesias-Fernández J, Ardèvol A, Dinev Z, Williams SJ, Bande O, Siriwardena A, Moreland C, Hu T, Smith DK, Gilbert HJ, Rovira C, Davies GJ. Inside Back Cover: The Reaction Coordinate of a Bacterial GH47 α-Mannosidase: A Combined Quantum Mechanical and Structural Approach (Angew. Chem. Int. Ed. 44/2012) Angewandte Chemie International Edition. 51: 11171-11171. DOI: 10.1002/Anie.201207917  0.779
2012 Thompson AJ, Dabin J, Iglesias-Fernández J, Ardèvol A, Dinev Z, Williams SJ, Bande O, Siriwardena A, Moreland C, Hu T, Smith DK, Gilbert HJ, Rovira C, Davies GJ. Innenrücktitelbild: The Reaction Coordinate of a Bacterial GH47 α-Mannosidase: A Combined Quantum Mechanical and Structural Approach (Angew. Chem. 44/2012) Angewandte Chemie. 124: 11333-11333. DOI: 10.1002/Ange.201207917  0.779
2011 Proietti Silvestri I, Andemarian F, Khairallah GN, Yap SW, Quach T, Tsegay S, Williams CM, O'Hair RA, Donnelly PS, Williams SJ. Copper(I)-catalyzed cycloaddition of silver acetylides and azides: incorporation of volatile acetylenes into the triazole core. Organic & Biomolecular Chemistry. 9: 6082-8. PMID 21748192 DOI: 10.1039/C1Ob05360D  0.764
2011 Cao B, White JM, Williams SJ. Synthesis of glycoconjugate fragments of mycobacterial phosphatidylinositol mannosides and lipomannan. Beilstein Journal of Organic Chemistry. 7: 369-77. PMID 21512604 DOI: 10.3762/Bjoc.7.47  0.311
2011 Yap S, Woodman OL, Crack PJ, Williams SJ. Synthesis of a hypoxia-targeted conjugate of the cardioprotective agent 3',4'-dihydroxyflavonol and evaluation of its ability to reduce ischaemia/reperfusion injury. Bioorganic & Medicinal Chemistry Letters. 21: 5102-6. PMID 21470863 DOI: 10.1016/J.Bmcl.2011.03.040  0.541
2011 Ash BL, Zanatta SD, Williams SJ, Lawrence AJ, Djouma E. The galanin-3 receptor antagonist, SNAP 37889, reduces operant responding for ethanol in alcohol-preferring rats. Regulatory Peptides. 166: 59-67. PMID 20736033 DOI: 10.1016/J.Regpep.2010.08.009  0.679
2011 Williams SJ, Thomas CJ, Boujaoude M, Gannon CT, Zanatta SD, Jarrott B, May CN, Woodman OL. Water soluble flavonol prodrugs that protect against ischaemia-reperfusion injury in rat hindlimb and sheep heart Medchemcomm. 2: 321-324. DOI: 10.1039/C0Md00240B  0.676
2010 Cao B, Williams SJ. Chemical approaches for the study of the mycobacterial glycolipids phosphatidylinositol mannosides, lipomannan and lipoarabinomannan. Natural Product Reports. 27: 919-47. PMID 20393651 DOI: 10.1039/C000604A  0.328
2010 Zhu Y, Suits MD, Thompson AJ, Chavan S, Dinev Z, Dumon C, Smith N, Moremen KW, Xiang Y, Siriwardena A, Williams SJ, Gilbert HJ, Davies GJ. Mechanistic insights into a Ca2+-dependent family of alpha-mannosidases in a human gut symbiont. Nature Chemical Biology. 6: 125-32. PMID 20081828 DOI: 10.1038/Nchembio.278  0.781
2010 Williams RJ, McGill NW, White JM, Williams SJ. Neighboring group participation in glycosylation reactions by 2,6-disubstituted 2-O-benzoyl groups: A mechanistic investigation Journal of Carbohydrate Chemistry. 29: 236-263. DOI: 10.1080/07328303.2010.508141  0.502
2010 Zanatta SD, Jarrott B, Williams SJ. Synthesis and preliminary pharmacological evaluation of aryl dithiolethiones with cyclooxygenase-2-selective inhibitory activity and hydrogen sulfide-releasing properties Australian Journal of Chemistry. 63: 946-957. DOI: 10.1071/Ch09517  0.713
2010 Shirbin SJ, Boughton BA, Zammit SC, Zanatta SD, Marcuccio SM, Hutton CA, Williams SJ. Copper-free palladium-catalyzed Sonogashira and Hiyama cross-couplings using aryl imidazol-1-ylsulfonates Tetrahedron Letters. 51: 2971-2974. DOI: 10.1016/J.Tetlet.2010.03.110  0.765
2010 Shirbin SJ, Boughton BA, Zammit SC, Zanatta SD, Marcuccio SM, Hutton CA, Williams SJ. ChemInform Abstract: Copper-Free Palladium-Catalyzed Sonogashira and Hiyama Cross-Couplings Using Aryl Imidazol-1-ylsulfonates. Cheminform. 41: no-no. DOI: 10.1002/chin.201036089  0.765
2010 Stick RV, Tilbrook DMG, Williams SJ. ChemInform Abstract: β-Acarbose. Part 8. The Synthesis of Some N-Linked Carba-Oligosaccharides. Cheminform. 31: no-no. DOI: 10.1002/chin.200010194  0.526
2010 Stick RV, Tilbrook DMG, Williams SJ. ChemInform Abstract: β-Acarbose. Part 7. Approaches Towards the Synthesis of Some N-Linked Carba-Oligosaccharides. Cheminform. 31: no-no. DOI: 10.1002/chin.200010193  0.525
2010 STICK RV, TILBROOK DMG, WILLIAMS SJ. ChemInform Abstract: The Selective Activation of Telluro- over Seleno-β-D- glucopyranosides as Glycosyl Donors: A Reactivity Scale for Various Telluro, Seleno, and Thio Sugars. Cheminform. 28: no-no. DOI: 10.1002/chin.199735258  0.527
2010 STICK RV, TILBROOK DMG, WILLIAMS SJ. ChemInform Abstract: The Synthesis of Some Seleno- and Telluro-β-D-glucopyranosides. Cheminform. 28: no-no. DOI: 10.1002/chin.199735257  0.529
2010 STICK RV, TILBROOK DMG, WILLIAMS SJ. ChemInform Abstract: 1,6-Epithio- and 1,6-Episeleno-β-D-glucopyranose: Useful Adjuncts in the Synthesis of 6-Deoxy-β-D-glucopyranosides. Cheminform. 28: no-no. DOI: 10.1002/chin.199731187  0.523
2010 DRIGUEZ H, MCAULIFFE JC, STICK RV, TILBROOK DMG, WILLIAMS SJ. ChemInform Abstract: A New Approach to Some 1,6-Dideoxy 1,6-Epithio Sugars. Cheminform. 27: no-no. DOI: 10.1002/chin.199635212  0.478
2010 BRUNOW G, STICK RV, SYRJAENEN K, TILBROOK DMG, WILLIAMS SJ. ChemInform Abstract: A Synthesis of (Z)-Octadec-9-enedioic Acid. Cheminform. 27: no-no. DOI: 10.1002/chin.199613094  0.496
2009 Zammit SC, Cox AJ, Gow RM, Zhang Y, Gilbert RE, Krum H, Kelly DJ, Williams SJ. Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates. Bioorganic & Medicinal Chemistry Letters. 19: 7003-6. PMID 19879136 DOI: 10.1016/J.Bmcl.2009.09.120  0.546
2009 Loft KJ, Bojarová P, Slámová K, Kren V, Williams SJ. Synthesis of sulfated glucosaminides for profiling substrate specificities of sulfatases and fungal beta-N-acetylhexosaminidases. Chembiochem : a European Journal of Chemical Biology. 10: 565-76. PMID 19156788 DOI: 10.1002/Cbic.200800656  0.642
2009 Bojarová P, Williams SJ. Aryl sulfamates are broad spectrum inactivators of sulfatases: effects on sulfatases from various sources. Bioorganic & Medicinal Chemistry Letters. 19: 477-80. PMID 19058962 DOI: 10.1016/J.Bmcl.2008.11.059  0.645
2009 Zanatta SD, Manallack DT, Jarrott B, Williams SJ. Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors. Bioorganic & Medicinal Chemistry Letters. 19: 459-61. PMID 19056264 DOI: 10.1016/J.Bmcl.2008.11.045  0.713
2009 Djouma E, Lawrence A, Zanatta S, Williams S. P.6.b.001 The galanin-3 antagonist, SNAP37889, reduces preference for operant-responding for ethanol in alcohol-preferring iP rats European Neuropsychopharmacology. 19: S643. DOI: 10.1016/S0924-977X(09)71036-3  0.672
2008 Yap S, Loft KJ, Woodman OL, Williams SJ. Discovery of water-soluble antioxidant flavonols without vasorelaxant activity. Chemmedchem. 3: 1572-9. PMID 18756557 DOI: 10.1002/Cmdc.200800146  0.546
2008 Bojarová P, Williams SJ. Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination. Current Opinion in Chemical Biology. 12: 573-81. PMID 18625336 DOI: 10.1016/J.Cbpa.2008.06.018  0.66
2008 Donnelly PS, Zanatta SD, Zammit SC, White JM, Williams SJ. 'Click' cycloaddition catalysts: copper(I) and copper(II) tris(triazolylmethyl)amine complexes. Chemical Communications (Cambridge, England). 2459-61. PMID 18491014 DOI: 10.1039/B719724A  0.751
2008 Bojarová P, Denehy E, Walker I, Loft K, De Souza DP, Woo LW, Potter BV, McConville MJ, Williams SJ. Direct evidence for ArO-S bond cleavage upon inactivation of Pseudomonas aeruginosa arylsulfatase by aryl sulfamates. Chembiochem : a European Journal of Chemical Biology. 9: 613-23. PMID 18288656 DOI: 10.1002/Cbic.200700579  0.694
2008 Watt JA, Gannon CT, Loft KJ, Dinev Z, Williams SJ. 'Click' preparation of carbohydrate 1-benzotriazoles, 1,4-disubstituted, and 1,4,5-trisubstituted triazoles and their utility as glycosyl donors Australian Journal of Chemistry. 61: 837-846. DOI: 10.1071/Ch08364  0.787
2008 Gilbert RE, Zhang Y, Zammit S, Williams S, Krum H, Kelly D. Reduced Kidney Fibrosis and Proteinuria in Advanced Experimental Diabetic Nephropathy Using a Purpose-Designed Direct Acting Antifibrotic Drug. Canadian Journal of Diabetes. 32: 308. DOI: 10.1016/S1499-2671(08)24040-2  0.464
2007 Wicki J, Williams SJ, Withers SG. Transition-state mimicry by glycosidase inhibitors: a critical kinetic analysis. Journal of the American Chemical Society. 129: 4530-1. PMID 17385869 DOI: 10.1021/Ja0707254  0.474
2007 Senaratne RH, Mougous JD, Reader JR, Williams SJ, Zhang T, Bertozzi CR, Riley LW. Vaccine efficacy of an attenuated but persistent Mycobacterium tuberculosis cysH mutant. Journal of Medical Microbiology. 56: 454-8. PMID 17374883 DOI: 10.1099/Jmm.0.46983-0  0.652
2007 Dinev Z, Gannon CT, Egan C, Watt JA, McConville MJ, Williams SJ. Galactose-derived phosphonate analogues as potential inhibitors of phosphatidylinositol biosynthesis in mycobacteria. Organic & Biomolecular Chemistry. 5: 952-9. PMID 17340011 DOI: 10.1039/B616450A  0.79
2006 van der Peet P, Gannon CT, Walker I, Dinev Z, Angelin M, Tam S, Ralton JE, McConville MJ, Williams SJ. Use of click chemistry to define the substrate specificity of Leishmania beta-1,2-mannosyltransferases. Chembiochem : a European Journal of Chemical Biology. 7: 1384-91. PMID 16841351 DOI: 10.1002/Cbic.200600159  0.784
2006 Sernee MF, Ralton JE, Dinev Z, Khairallah GN, O'Hair RA, Williams SJ, McConville MJ. Leishmania beta-1,2-mannan is assembled on a mannose-cyclic phosphate primer. Proceedings of the National Academy of Sciences of the United States of America. 103: 9458-63. PMID 16766650 DOI: 10.1073/Pnas.0603539103  0.78
2006 Dinev Z, Wardak AZ, Brownlee RT, Williams SJ. A convenient gram-scale synthesis of uridine diphospho(13C6)glucose. Carbohydrate Research. 341: 1743-7. PMID 16603138 DOI: 10.1016/J.Carres.2006.02.033  0.777
2006 Senaratne RH, De Silva AD, Williams SJ, Mougous JD, Reader JR, Zhang T, Chan S, Sidders B, Lee DH, Chan J, Bertozzi CR, Riley LW. 5'-Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice. Molecular Microbiology. 59: 1744-53. PMID 16553880 DOI: 10.1111/J.1365-2958.2006.05075.X  0.711
2006 Williams SJ, Hekmat O, Withers SG. Synthesis and testing of mechanism-based protein-profiling probes for retaining endo-glycosidases. Chembiochem : a European Journal of Chemical Biology. 7: 116-24. PMID 16397879 DOI: 10.1002/Cbic.200500279  0.502
2005 Hekmat O, Kim YW, Williams SJ, He S, Withers SG. Active-site peptide "fingerprinting" of glycosidases in complex mixtures by mass spectrometry. Discovery of a novel retaining beta-1,4-glycanase in Cellulomonas fimi. The Journal of Biological Chemistry. 280: 35126-35. PMID 16085650 DOI: 10.1074/Jbc.M508434200  0.481
2004 Gloster TM, Williams SJ, Roberts S, Tarling CA, Wicki J, Withers SG, Davies GJ. Atomic resolution analyses of the binding of xylobiose-derived deoxynojirimycin and isofagomine to xylanase Xyn10A. Chemical Communications (Cambridge, England). 1794-5. PMID 15306887 DOI: 10.1039/B405152A  0.482
2004 Woodruff PJ, Carlson BL, Siridechadilok B, Pratt MR, Senaratne RH, Mougous JD, Riley LW, Williams SJ, Bertozzi CR. Trehalose is required for growth of Mycobacterium smegmatis. The Journal of Biological Chemistry. 279: 28835-43. PMID 15102847 DOI: 10.1074/Jbc.M313103200  0.778
2003 Gloster T, Williams SJ, Tarling CA, Roberts S, Dupont C, Jodoin P, Shareck F, Withers SG, Davies GJ. A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer. Chemical Communications (Cambridge, England). 944-5. PMID 12744311 DOI: 10.1039/B301829F  0.509
2002 Mougous JD, Leavell MD, Senaratne RH, Leigh CD, Williams SJ, Riley LW, Leary JA, Bertozzi CR. Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach. Proceedings of the National Academy of Sciences of the United States of America. 99: 17037-42. PMID 12482950 DOI: 10.1073/Pnas.252514899  0.695
2002 Williams SJ, Mark BL, Vocadlo DJ, James MN, Withers SG. Aspartate 313 in the Streptomyces plicatus hexosaminidase plays a critical role in substrate-assisted catalysis by orienting the 2-acetamido group and stabilizing the transition state. The Journal of Biological Chemistry. 277: 40055-65. PMID 12171933 DOI: 10.1074/Jbc.M206481200  0.672
2002 Mougous JD, Green RE, Williams SJ, Brenner SE, Bertozzi CR. Sulfotransferases and sulfatases in mycobacteria. Chemistry & Biology. 9: 767-76. PMID 12144918 DOI: 10.1016/S1074-5521(02)00175-8  0.672
2002 Williams SJ, Senaratne RH, Mougous JD, Riley LW, Bertozzi CR. 5'-adenosinephosphosulfate lies at a metabolic branch point in mycobacteria. The Journal of Biological Chemistry. 277: 32606-15. PMID 12072441 DOI: 10.1074/Jbc.M204613200  0.695
2002 Williams SJ, Withers SG. Glycosynthases: Mutant Glycosidases for Glycoside Synthesis Australian Journal of Chemistry. 55: 3. DOI: 10.1071/Ch02005  0.504
2002 Leavell MD, Mougous JD, Senaratne RH, Leigh C, Williams SJ, Riley L, Bertozzi CR, Leary JA. Strategy for the identification of sulfated metabolites in bacterial cell extracts using FT-ICR, isotopic labeling and genetics Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 415-416.  0.572
2000 Notenboom V, Williams SJ, Hoos R, Withers SG, Rose DR. Detailed structural analysis of glycosidase/inhibitor interactions: complexes of Cex from Cellulomonas fimi with xylobiose-derived aza-sugars. Biochemistry. 39: 11553-63. PMID 10995222 DOI: 10.1021/Bi0010625  0.49
2000 Williams SJ, Withers SG. Glycosyl fluorides in enzymatic reactions. Carbohydrate Research. 327: 27-46. PMID 10968675 DOI: 10.1016/S0008-6215(00)00041-0  0.528
2000 Skelton BW, Stick RV, Tilbrook DMG, White AH, Williams SJ. Investigations into the Chemistry of Some 1,6-Epithio and 1,6-Episeleno ß-D-Glucopyranoses Australian Journal of Chemistry. 53: 389. DOI: 10.1071/Ch99164  0.586
2000 Williams SJ, Hoos R, Withers SG. Nanomolar versus Millimolar Inhibition by Xylobiose-Derived Azasugars:  Significant Differences between Two Structurally Distinct Xylanases Journal of the American Chemical Society. 122: 2223-2235. DOI: 10.1021/Ja993805J  0.507
2000 Williams SJ, Notenboom V, Wicki J, Rose DR, Withers SG. A New, Simple, High-Affinity Glycosidase Inhibitor:  Analysis of Binding through X-ray Crystallography, Mutagenesis, and Kinetic Analysis Journal of the American Chemical Society. 122: 4229-4230. DOI: 10.1021/Ja0002870  0.442
1999 Tilbrook MG, Stick RV, Williams SJ. β-Acarbose. VIII.The Synthesis of Some N-Linked Carba-Oligosaccharides Australian Journal of Chemistry. 52: 895. DOI: 10.1071/Ch99031  0.595
1999 Tilbrook MG, Stick RV, Williams SJ. β-Acarbose. VII. Approaches Towards the Synthesis of Some N-Linked Carba-Oligosaccharides Australian Journal of Chemistry. 52: 885. DOI: 10.1071/Ch99030  0.596
1999 Stick RV, Tilbrook DMG, Williams SJ. 1,6-epithio- and 1,6-episeleno-beta-D-glucopyranose: Useful adjuncts in the synthesis of 6-deoxy-beta-D-glucopyranosides Australian Journal of Chemistry. 52: 685-693. DOI: 10.1071/Ch99009  0.583
1999 Stick RV, Tilbrook DMG, Williams SJ. 1,6-Epithio- and 1,6-Episeleno-β-D-glucopyranose: Useful Adjuncts in the Synthesis of 6-Deoxy-β-D-glucopyranosides Australian Journal of Chemistry. 52: 685. DOI: 10.1016/S0040-4039(97)00458-9  0.586
1997 Stick RV, Tilbrook DMG, Williams SJ. The Selective Activation of Telluro- over Seleno-β-D-glucopyranosides as Glycosyl Donors: a Reactivity Scale for Various Telluro, Seleno and Thio Sugars Australian Journal of Chemistry. 50: 237. DOI: 10.1071/C96207  0.588
1997 Stick RV, Tilbrook DMG, Williams SJ. The Synthesis of Some Seleno- and Telluro-β-D-glucopyranosides Australian Journal of Chemistry. 50: 233. DOI: 10.1071/C96202  0.575
1997 Stick RV, Matthew D, Tilbrook G, Williams SJ. 1,6-epithio- and 1,6-episeleno-β-D-glucopyranose: Useful Adjuncts in the synthesis of 6-deoxy-β-D-glucopyranosides Tetrahedron Letters. 38: 2741-2744. DOI: 10.1016/S0040-4039(97)00458-9  0.521
1996 Driguez H, Mcauliffe J, Stick R, Tilbrook D, Williams S. A New Approach to Some 1,6-Dideoxy 1,6-Epithio Sugars Australian Journal of Chemistry. 49: 343. DOI: 10.1071/Ch9960343  0.585
1995 Brunow G, Stick R, Syrjanen K, Tilbrook D, Williams S. A Synthesis of (Z)-Octadec-9-enedioic Acid Australian Journal of Chemistry. 48: 1893. DOI: 10.1071/Ch9951893  0.556
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