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Ralph Weissleder - Publications

Affiliations: 
Center for Systems Biology Harvard Medical School, Boston, MA, United States 
Website:
https://sysbio.med.harvard.edu/ralph-weissleder
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Year Citation  Score
2024 Enbergs N, Halabi EA, Goubet AG, Schleyer K, Fredrich IR, Kohler RH, Garris CS, Pittet MJ, Weissleder R. Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2309026. PMID 38342608 DOI: 10.1002/advs.202309026  0.783
2023 Korolj A, Kohler RH, Scott E, Halabi EA, Lucas K, Carlson JCT, Weissleder R. Perfusion Window Chambers Enable Interventional Analyses of Tumor Microenvironments. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2304886. PMID 37870204 DOI: 10.1002/advs.202304886  0.782
2023 Fredrich IR, Halabi EA, Kohler RH, Ge X, Garris CS, Weissleder R. Highly Active Myeloid Therapy for Cancer. Acs Nano. 17: 20666-20679. PMID 37824733 DOI: 10.1021/acsnano.3c08034  0.775
2023 Das R, Halabi EA, Fredrich IR, Oh J, Peterson HM, Ge X, Scott E, Kohler RH, Garris CS, Weissleder R. Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2303576. PMID 37814359 DOI: 10.1002/advs.202303576  0.771
2023 Halabi EA, Weissleder R. Light-Deactivated Fluorescent Probes (FLASH-Off) for Multiplexed Imaging. Journal of the American Chemical Society. PMID 37018018 DOI: 10.1021/jacs.3c00170  0.76
2023 Turco V, Pfleiderer K, Hunger J, Horvat NK, Karimian-Jazi K, Schregel K, Fischer M, Brugnara G, Jähne K, Sturm V, Streibel Y, Nguyen D, Altamura S, Agardy DA, Soni SS, ... ... Weissleder R, et al. T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles. Nature Communications. 14: 771. PMID 36774352 DOI: 10.1038/s41467-023-36321-6  0.728
2022 Lugani S, Halabi EA, Oh J, Kohler R, Peterson H, Breakefield XO, Chiocca EAA, Miller MA, Garris C, Weissleder R. Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti-Tumor Immunity in Murine Glioblastoma. Advanced Materials (Deerfield Beach, Fla.). e2208782. PMID 36427266 DOI: 10.1002/adma.202208782  0.782
2022 Ko J, Lucas K, Kohler R, Halabi EA, Wilkovitsch M, Carlson JCT, Weissleder R. In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2200064. PMID 35750648 DOI: 10.1002/advs.202200064  0.79
2022 Ko J, Wilkovitsch M, Oh J, Kohler RH, Bolli E, Pittet MJ, Vinegoni C, Sykes DB, Mikula H, Weissleder R, Carlson JCT. Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes. Nature Biotechnology. PMID 35654978 DOI: 10.1038/s41587-022-01339-6  0.659
2022 Ng TSC, Hu H, Kronister S, Lee C, Li R, Gerosa L, Stopka SA, Burgenske DM, Khurana I, Regan MS, Vallabhaneni S, Putta N, Scott E, Matvey D, Giobbie-Hurder A, ... ... Weissleder R, et al. Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy. Science Advances. 8: eabl6339. PMID 35486732 DOI: 10.1126/sciadv.abl6339  0.65
2021 Pfirschke C, Zilionis R, Engblom C, Messemaker M, Zou AE, Rickelt S, Gort-Freitas NA, Lin Y, Bill R, Siwicki M, Gungabeesoon J, Sprachman MM, Marquard AN, Rodell CB, Cuccarese MF, ... ... Weissleder R, et al. Macrophage-targeted therapy unlocks antitumoral crosstalk between IFN Cancer Immunology Research. PMID 34795032 DOI: 10.1158/2326-6066.CIR-21-0326  0.752
2021 Koch PD, Quintana J, Ahmed M, Kohler RH, Weissleder R. SMALL MOLECULE IMAGING AGENT FOR MUTANT KRAS G12C. Advanced Therapeutics. 4. PMID 33997272 DOI: 10.1002/adtp.202000290  0.756
2021 Li R, Ng TSC, Wang SJ, Prytyskach M, Rodell CB, Mikula H, Kohler RH, Garlin MA, Lauffenburger DA, Parangi S, Dinulescu DM, Bardeesy N, Weissleder R, Miller MA. Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer. Nature Nanotechnology. PMID 33958764 DOI: 10.1038/s41565-021-00897-1  0.633
2020 Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R. Ultra-fast cycling for multiplexed cellular fluorescence imaging. Angewandte Chemie (Weinheim An Der Bergstrasse, Germany). 132: 6906-6913. PMID 34366494 DOI: 10.1002/ange.201915153  0.743
2020 Wilkovitsch M, Haider M, Sohr B, Herrmann B, Klubnick J, Weissleder R, Carlson JCT, Mikula H. A Cleavable C-Symmetric -Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes. Journal of the American Chemical Society. PMID 33119297 DOI: 10.1021/jacs.0c07922  0.604
2020 Feruglio P, Vinegoni C, Weissleder R. Extended dynamic range imaging for noise mitigation in fluorescence anisotropy imaging. Journal of Biomedical Optics. 25. PMID 32820624 DOI: 10.1117/1.Jbo.25.8.086003  0.372
2020 Luthria G, Li R, Wang S, Prytyskach M, Kohler RH, Lauffenburger DA, Mitchison TJ, Weissleder R, Miller MA. In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells. Nature Communications. 11: 3521. PMID 32665556 DOI: 10.1038/S41467-020-17147-Y  0.353
2020 Wang SJ, Li R, Ng TSC, Luthria G, Oudin MJ, Prytyskach M, Kohler RH, Weissleder R, Lauffenburger DA, Miller MA. Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Science Advances. 6: eaaz8521. PMID 32494745 DOI: 10.1126/Sciadv.Aaz8521  0.323
2020 Vinegoni C, Fumene Feruglio P, Courties G, Schmidt S, Hulsmans M, Lee S, Wang R, Sosnovik D, Nahrendorf M, Weissleder R. Fluorescence microscopy tensor imaging representations for large-scale dataset analysis. Scientific Reports. 10: 5632. PMID 32221334 DOI: 10.1038/S41598-020-62233-2  0.36
2020 Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R. Ultra-fast cycling for multiplexed cellular fluorescence imaging. Angewandte Chemie (International Ed. in English). PMID 32004403 DOI: 10.1002/Anie.201915153  0.754
2020 Ng TSC, Garlin MA, Weissleder R, Miller MA. Improving nanotherapy delivery and action through image-guided systems pharmacology. Theranostics. 10: 968-997. PMID 31938046 DOI: 10.7150/Thno.37215  0.396
2020 Koch PD, Rodell CB, Kohler RH, Pittet MJ, Weissleder R. Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy. Cell Chemical Biology. 27: 94-104.e5. PMID 31902676 DOI: 10.1016/J.Chembiol.2019.12.007  0.338
2020 Weissleder R, Lee H. Automated molecular-image cytometry and analysis in modern oncology Nature Reviews Materials. 5: 409-422. DOI: 10.1038/S41578-020-0180-6  0.342
2020 Li R, Ng TSC, Garlin MA, Weissleder R, Miller MA. Understanding the In Vivo Fate of Advanced Materials by Imaging Advanced Functional Materials. 30: 1910369. DOI: 10.1002/Adfm.201910369  0.332
2019 Rodell CB, Ahmed MS, Garris CS, Pittet MJ, Weissleder R. Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy. Theranostics. 9: 8426-8436. PMID 31879528 DOI: 10.7150/Thno.35434  0.753
2019 Koch PD, Ahmed MS, Kohler RH, Li R, Weissleder R. Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand. Acs Chemical Biology. PMID 31809013 DOI: 10.1021/Acschembio.9B00724  0.759
2019 Rodell CB, Koch PD, Weissleder R. Screening for new macrophage therapeutics. Theranostics. 9: 7714-7729. PMID 31695796 DOI: 10.7150/Thno.34421  0.341
2019 Vinegoni C, Feruglio PF, Weissleder R. High dynamic range fluorescence imaging. Ieee Journal of Selected Topics in Quantum Electronics : a Publication of the Ieee Lasers and Electro-Optics Society. 25. PMID 31598059 DOI: 10.1109/Jstqe.2018.2881608  0.383
2019 Huang CH, Park YI, Lin HY, Pathania D, Park KS, Avila-Wallace M, Castro CM, Weissleder R, Lee H. Compact and Filter-Free Luminescence Biosensor for Mobile Diagnoses. Acs Nano. PMID 31461265 DOI: 10.1021/Acsnano.9B05634  0.365
2019 Li R, Attari A, Prytyskach M, Garlin MA, Weissleder R, Miller MA. Single-Cell Intravital Microscopy of Trastuzumab Quantifies Heterogeneous in vivo Kinetics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 31423731 DOI: 10.1002/Cyto.A.23872  0.363
2019 Florian S, Iwamoto Y, Coughlin M, Weissleder R, Mitchison TJ. A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor. Proceedings of the National Academy of Sciences of the United States of America. PMID 31101720 DOI: 10.1073/Pnas.1702372116  0.3
2019 Zaborowski MP, Lee K, Na YJ, Sammarco A, Zhang X, Iwanicki M, Cheah PS, Lin HY, Zinter M, Chou CY, Fulci G, Tannous BA, Lai CP, Birrer MJ, Weissleder R, et al. Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles. Cell Reports. 27: 255-268.e6. PMID 30943406 DOI: 10.1016/J.Celrep.2019.03.003  0.324
2019 Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA, Weissleder R, Kantarci AG, Tannous BA. Radiation-Induced Targeted Nanoparticle-Based Gene Delivery for Brain Tumor Therapy. Acs Nano. PMID 30916923 DOI: 10.1021/Acsnano.8B08177  0.328
2019 Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre A, Nahrendorf M, Weissleder R. A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart. Bioconjugate Chemistry. PMID 30615425 DOI: 10.1021/Acs.Bioconjchem.8B00882  0.74
2019 Vinegoni C, Lee S, Feruglio PF, Weissleder R. Advanced Motion Compensation Methods for Intravital Optical Microscopy. Ieee Journal of Selected Topics in Quantum Electronics : a Publication of the Ieee Lasers and Electro-Optics Society. 20. PMID 24273405 DOI: 10.1109/Jstqe.2013.2279314  0.335
2019 Shao F, Yuan H, Josephson L, Weissleder R, Hilderbrand SA. Facile Synthesis of Monofunctional Pentamethine Carbocyanine Fluorophores. Dyes and Pigments : An International Journal. 90: 119-122. PMID 21475610 DOI: 10.1016/J.Dyepig.2010.12.008  0.301
2019 Wang S, Weissleder R, Lauffenburger D, Miller M. Abstract LB-A03: Molecular systems-guided imaging of multicellular in situ adaptation to targeted therapy in BRAF-mutant cancer Molecular Cancer Therapeutics. 18. DOI: 10.1158/1535-7163.Targ-19-Lb-A03  0.363
2018 Rodell CB, Arlauckas SP, Cuccarese MF, Garris CS, Li R, Ahmed MS, Kohler RH, Pittet MJ, Weissleder R. TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nature Biomedical Engineering. 2: 578-588. PMID 31015631 DOI: 10.1038/S41551-018-0236-8  0.743
2018 Arlauckas SP, Garren SB, Garris CS, Kohler RH, Oh J, Pittet MJ, Weissleder R. Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages. Theranostics. 8: 5842-5854. PMID 30613266 DOI: 10.7150/Thno.26888  0.37
2018 Miller MA, Mikula H, Luthria G, Li R, Kronister S, Prytyskach M, Kohler RH, Mitchison T, Weissleder R. Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation. Acs Nano. PMID 30550257 DOI: 10.1021/Acsnano.8B07954  0.675
2018 Kim HY, Li R, Ng TSC, Courties G, Rodell CB, Prytyskach M, Kohler RH, Pittet M, Nahrendorf M, Weissleder R, Miller MA. Quantitative Imaging of Tumor Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin. Acs Nano. PMID 30508377 DOI: 10.1021/Acsnano.8B04338  0.409
2018 Kim SJ, Wang C, Zhao B, Im H, Min J, Choi HJ, Tadros J, Choi NR, Castro CM, Weissleder R, Lee H, Lee K. Deep transfer learning-based hologram classification for molecular diagnostics. Scientific Reports. 8: 17003. PMID 30451953 DOI: 10.1038/S41598-018-35274-X  0.3
2018 Pineda JJ, Miller MA, Song Y, Kuhn H, Mikula H, Tallapragada N, Weissleder R, Mitchison TJ. Site occupancy calibration of taxane pharmacology in live cells and tissues. Proceedings of the National Academy of Sciences of the United States of America. PMID 30429313 DOI: 10.1073/Pnas.1800047115  0.648
2018 Oh J, Magnuson A, Benoist C, Pittet MJ, Weissleder R. Age-related tumor growth in mice is related to integrin α 4 in CD8+ T cells. Jci Insight. 3. PMID 30385729 DOI: 10.1172/Jci.Insight.122961  0.304
2018 Giedt RJ, Pathania D, Carlson JCT, McFarland PJ, Del Castillo AF, Juric D, Weissleder R. Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens. Nature Communications. 9: 4550. PMID 30382095 DOI: 10.1038/S41467-018-07002-6  0.336
2018 Magnuson AM, Kiner E, Ergun A, Park JS, Asinovski N, Ortiz-Lopez A, Kilcoyne A, Paoluzzi-Tomada E, Weissleder R, Mathis D, Benoist C. Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types. Proceedings of the National Academy of Sciences of the United States of America. PMID 30348759 DOI: 10.1073/Pnas.1810580115  0.306
2018 Pittet MJ, Garris CS, Arlauckas SP, Weissleder R. Recording the wild lives of immune cells. Science Immunology. 3. PMID 30194240 DOI: 10.1126/Sciimmunol.Aaq0491  0.352
2018 Aganj I, Harisinghani MG, Weissleder R, Fischl B. Unsupervised Medical Image Segmentation Based on the Local Center of Mass. Scientific Reports. 8: 13012. PMID 30158534 DOI: 10.1038/S41598-018-31333-5  0.335
2018 Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz GR, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson FE, Jung Y, Désogère P, Vinegoni C, Caravan P, Weissleder R, et al. Imaging the Vascular Bone Marrow Niche During Inflammatory Stress. Circulation Research. PMID 29980569 DOI: 10.1161/Circresaha.118.313302  0.312
2018 Sahin A, Sanchez C, Bullain S, Waterman P, Weissleder R, Carter BS. Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma. Plos One. 13: e0199414. PMID 29975720 DOI: 10.1371/Journal.Pone.0199414  0.301
2018 Vinegoni C, Feruglio PF, Gryczynski I, Mazitschek R, Weissleder R. Fluorescence anisotropy imaging in drug discovery. Advanced Drug Delivery Reviews. PMID 29410158 DOI: 10.1016/J.Addr.2018.01.019  0.345
2018 Carlson J, Mikula H, Weissleder R. Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage. Journal of the American Chemical Society. PMID 29384666 DOI: 10.1021/Jacs.7B11217  0.628
2018 Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca EA, Breakefield XO, Lee H, Weissleder R. Multiplexed Profiling of Single Extracellular Vesicles. Acs Nano. PMID 29286635 DOI: 10.1021/Acsnano.7B07060  0.303
2017 Miller MA, Kim E, Cuccarese MF, Plotkin AL, Prytyskach M, Kohler RH, Pittet MJ, Weissleder R. Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease. Chemical Communications (Cambridge, England). 54: 42-45. PMID 29185561 DOI: 10.1039/C7Cc07581B  0.411
2017 Min C, Park J, Mun JK, Lim Y, Min J, Lim JW, Kang DM, Ahn HK, Shin TH, Cheon J, Lee HS, Weissleder R, Castro CM, Lee H. Integrated microHall magnetometer to measure the magnetic properties of nanoparticles. Lab On a Chip. PMID 29067383 DOI: 10.1039/C7Lc00934H  0.305
2017 Mohan JF, Kohler RH, Hill JA, Weissleder R, Mathis D, Benoist C. Imaging the emergence and natural progression of spontaneous autoimmune diabetes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28839093 DOI: 10.1073/Pnas.1707381114  0.309
2017 Miller MA, Askevold B, Mikula H, Kohler RH, Pirovich D, Weissleder R. Nano-palladium is a cellular catalyst for in vivo chemistry. Nature Communications. 8: 15906. PMID 28699627 DOI: 10.1038/Ncomms15906  0.742
2017 Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R. Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging. Nature Protocols. 12: 1472-1497. PMID 28686582 DOI: 10.1038/Nprot.2017.043  0.369
2017 Miller MA, Weissleder R. Imaging of anticancer drug action in single cells. Nature Reviews. Cancer. 17: 399-414. PMID 28642603 DOI: 10.1038/Nrc.2017.41  0.355
2017 Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR. Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer. Science Advances. 3: e1700341. PMID 28630930 DOI: 10.1126/Sciadv.1700341  0.334
2017 Miller MA, Chandra R, Cuccarese MF, Pfirschke C, Engblom C, Stapleton S, Adhikary U, Kohler RH, Mohan JF, Pittet MJ, Weissleder R. Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts. Science Translational Medicine. 9. PMID 28566423 DOI: 10.1126/Scitranslmed.Aal0225  0.375
2017 Arlauckas SP, Garris CS, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ. In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy. Science Translational Medicine. 9. PMID 28490665 DOI: 10.1126/Scitranslmed.Aal3604  0.431
2017 Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R. Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging. Theranostics. 7: 1257-1265. PMID 28435463 DOI: 10.7150/Thno.18238  0.703
2017 Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R. Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging. Nature Communications. 8: 14293. PMID 28176769 DOI: 10.1038/Ncomms14293  0.362
2017 Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, ... ... Weissleder R, et al. Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease. Nature Communications. 8: 14064. PMID 28091604 DOI: 10.1038/Ncomms14064  0.339
2017 Weissleder R. Abstract IA13: Imaging drug delivery and nanotherapeutics Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-Ia13  0.32
2016 Gee MS, Ghazani AA, Haq R, Wargo JA, Sebas M, Sullivan RJ, Lee H, Weissleder R. Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27993725 DOI: 10.1016/J.Nano.2016.12.006  0.342
2016 Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R. Quantitating drug-target engagement in single cells in vitro and in vivo. Nature Chemical Biology. PMID 27918558 DOI: 10.1038/Nchembio.2248  0.428
2016 Pucci F, Rickelt S, Newton AP, Garris C, Nunes E, Evavold C, Pfirschke C, Engblom C, Mino-Kenudson M, Hynes RO, Weissleder R, Pittet MJ. PF4 Promotes Platelet Production and Lung Cancer Growth. Cell Reports. 17: 1764-1772. PMID 27829148 DOI: 10.1016/J.Celrep.2016.10.031  0.316
2016 Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R. Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response. Scientific Reports. 6: 32985. PMID 27609668 DOI: 10.1038/Srep32985  0.338
2016 Weissleder R, Schwaiger MC, Gambhir SS, Hricak H. Imaging approaches to optimize molecular therapies. Science Translational Medicine. 8: 355ps16. PMID 27605550 DOI: 10.1126/Scitranslmed.Aaf3936  0.379
2016 Hong S, Pirovich D, Kilcoyne A, Huang CH, Lee H, Weissleder R. Supramolecular Metallo-Bioadhesive for Minimally Invasive Use. Advanced Materials (Deerfield Beach, Fla.). PMID 27515068 DOI: 10.1002/Adma.201602606  0.74
2016 Vinegoni C, Dubach JM, Feruglio PF, Weissleder R. Two-photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement. Ieee Journal of Selected Topics in Quantum Electronics : a Publication of the Ieee Lasers and Electro-Optics Society. 22. PMID 27440991 DOI: 10.1109/Jstqe.2015.2501384  0.405
2016 Meimetis LG, Giedt RJ, Mikula H, Carlson JC, Kohler RH, Pirovich DB, Weissleder R. Fluorescent vinblastine probes for live cell imaging. Chemical Communications (Cambridge, England). PMID 27439765 DOI: 10.1039/C6Cc04129A  0.769
2016 Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, ... ... Weissleder R, et al. RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction. Science Translational Medicine. 8: 342ra80. PMID 27280687 DOI: 10.1126/Scitranslmed.Aaf1435  0.318
2016 Miller MA, Weissleder R. Imaging the pharmacology of nanomaterials by intravital microscopy: Towards understanding their biological behavior. Advanced Drug Delivery Reviews. PMID 27266447 DOI: 10.1016/J.Addr.2016.05.023  0.406
2016 Song J, Leon Swisher C, Im H, Jeong S, Pathania D, Iwamoto Y, Pivovarov M, Weissleder R, Lee H. Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography. Scientific Reports. 6: 24681. PMID 27098438 DOI: 10.1038/Srep24681  0.31
2016 Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, Alvarez D, Sprachman M, Evavold C, Magnuson A, von Andrian UH, Glatz K, Breakefield XO, Mempel TR, Weissleder R, et al. SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions. Science (New York, N.Y.). PMID 26989197 DOI: 10.1126/Science.Aaf1328  0.369
2016 Pfirschke C, Engblom C, Rickelt S, Cortez-Retamozo V, Garris C, Pucci F, Yamazaki T, Poirier-Colame V, Newton A, Redouane Y, Lin YJ, Wojtkiewicz G, Iwamoto Y, Mino-Kenudson M, Huynh TG, ... ... Weissleder R, et al. Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy. Immunity. 44: 343-354. PMID 26872698 DOI: 10.1016/J.Immuni.2015.11.024  0.391
2016 Roy J, Kim B, Hill E, Visconti P, Krapf D, Vinegoni C, Weissleder R, Brown D, Breton S. Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging. Nature Communications. 7: 10666. PMID 26868824 DOI: 10.1038/Ncomms10666  0.341
2016 Miller MA, Pittet M, Weissleder R. Abstract B133: In vivo imaging of innate immune cells to measure drug response Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B133  0.422
2016 Dougan M, Ingram J, Blomberg O, Rashidian M, Keliher E, Weissleder R, Almo S, Ploegh H. Abstract B021: Single domain antibodies targeting CTLA-4 demonstrate a critical role for Fc in the antitumor response Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B021  0.322
2016 Giedt RJ, Fergulio PF, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R. Abstract 234: Mitochondrial morphology as a biomarker of cancer phenotype and drug response Cancer Research. 76: 234-234. DOI: 10.1158/1538-7445.Am2016-234  0.312
2016 Dubach M, Weissleder R. Abstract 2093: Imaging single cell drug target engagement in vivo reveals heterogeneous fractional occupancy Cancer Research. 76: 2093-2093. DOI: 10.1158/1538-7445.Am2016-2093  0.383
2016 Vinegoni C, Swisher CL, Feruglio PF, Giedt RJ, Rousso DL, Stapleton S, Weissleder R. Real-time high dynamic range laser scanning microscopy Nature Communications. 7. DOI: 10.1038/Ncomms11077  0.356
2015 Koo H, Choi M, Kim E, Hahn SK, Weissleder R, Yun SH. Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small (Weinheim An Der Bergstrasse, Germany). 11: 6458-66. PMID 26768353 DOI: 10.1002/Smll.201502972  0.37
2015 Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R. Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies. Bioconjugate Chemistry. PMID 26684717 DOI: 10.1021/Acs.Bioconjchem.5B00630  0.392
2015 Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R, Azzi J, Nicolay K, Tannous BA. Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging. Scientific Reports. 5: 17220. PMID 26610702 DOI: 10.1038/Srep17220  0.381
2015 Weissleder R, Nahrendorf M. Advancing biomedical imaging. Proceedings of the National Academy of Sciences of the United States of America. 112: 14424-8. PMID 26598657 DOI: 10.1073/Pnas.1508524112  0.351
2015 Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R. Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle. Science Translational Medicine. 7: 314ra183. PMID 26582898 DOI: 10.1126/Scitranslmed.Aac6522  0.402
2015 Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nature Communications. 6: 8692. PMID 26503691 DOI: 10.1038/Ncomms9692  0.391
2015 Vinegoni C, Aguirre AD, Lee S, Weissleder R. Imaging the beating heart in the mouse using intravital microscopy techniques. Nature Protocols. 10: 1802-1819. PMID 26492138 DOI: 10.1038/Nprot.2015.119  0.372
2015 Ye YX, Calcagno C, Binderup T, Courties G, Keliher E, Wojtkiewicz GR, Iwamoto Y, Tang J, Perez-Medina C, Mani V, Ishino S, Johnbeck CB, Knigge U, Fayad ZA, Libby P, ... Weissleder R, et al. Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis. Circulation Research. PMID 26394773 DOI: 10.1161/Circresaha.115.307024  0.353
2015 Whitley MJ, Weissleder R, Kirsch DG. Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer. Seminars in Radiation Oncology. 25: 313-21. PMID 26384279 DOI: 10.1016/J.Semradonc.2015.05.005  0.413
2015 Clardy SM, Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R. Rapid, high efficiency isolation of pancreatic ß-cells. Scientific Reports. 5: 13681. PMID 26330153 DOI: 10.1038/Srep13681  0.309
2015 Konishi M, Erdem SS, Weissleder R, Lichtman AH, McCarthy J, Libby P. Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis. Circulation Research. PMID 26199323 DOI: 10.1161/Circresaha.115.306364  0.345
2015 Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M. Engineered Trehalose Permeable to Mammalian Cells. Plos One. 10: e0130323. PMID 26115179 DOI: 10.1371/Journal.Pone.0130323  0.311
2015 Glenn DR, Lee K, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H, Walsworth RL, Connolly CB. Single-cell magnetic imaging using a quantum diamond microscope. Nature Methods. PMID 26098019 DOI: 10.1038/Nmeth.3449  0.397
2015 Vinegoni C, Lee S, Aguirre AD, Weissleder R. New techniques for motion-artifact-free in vivo cardiac microscopy. Frontiers in Physiology. 6: 147. PMID 26029116 DOI: 10.3389/Fphys.2015.00147  0.36
2015 Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R. Advances in measuring single-cell pharmacology in vivo. Drug Discovery Today. 20: 1087-92. PMID 26024776 DOI: 10.1016/J.Drudis.2015.05.011  0.336
2015 Kim E, Yang KS, Kohler RH, Dubach JM, Mikula H, Weissleder R. Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression. Bioconjugate Chemistry. PMID 26017814 DOI: 10.1021/Acs.Bioconjchem.5B00152  0.702
2015 Turetsky A, Lee K, Song J, Giedt RJ, Kim E, Kovach AE, Hochberg EP, Castro CM, Lee H, Weissleder R. On chip analysis of CNS lymphoma in cerebrospinal fluid. Theranostics. 5: 796-804. PMID 26000053 DOI: 10.7150/Thno.11220  0.327
2015 Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R. Single cell resolution in vivo imaging of DNA damage following PARP inhibition. Scientific Reports. 5: 10129. PMID 25984718 DOI: 10.1038/Srep10129  0.336
2015 Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, Breakefield XO. Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters. Nature Communications. 6: 7029. PMID 25967391 DOI: 10.1038/Ncomms8029  0.311
2015 Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL. Noninvasive imaging of immune responses. Proceedings of the National Academy of Sciences of the United States of America. 112: 6146-51. PMID 25902531 DOI: 10.1073/Pnas.1502609112  0.406
2015 Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R, Danuser G, Mitchison TJ. In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy. Nature Methods. 12: 577-85. PMID 25867850 DOI: 10.1038/Nmeth.3363  0.379
2015 Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, ... ... Weissleder R, et al. Macrophages retain hematopoietic stem cells in the spleen via VCAM-1. The Journal of Experimental Medicine. 212: 497-512. PMID 25800955 DOI: 10.1084/Jem.20141642  0.314
2015 Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C, Mathis D, Weissleder R. Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients. Proceedings of the National Academy of Sciences of the United States of America. 112: 2139-44. PMID 25650428 DOI: 10.1073/Pnas.1424993112  0.327
2014 Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nature Communications. 5: 5662. PMID 25489927 DOI: 10.1038/Ncomms6662  0.318
2014 Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D. Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells. Elife. 3: e04631. PMID 25407682 DOI: 10.7554/Elife.04631  0.304
2014 Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R. Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin. Science Translational Medicine. 6: 261ra152. PMID 25378644 DOI: 10.1126/Scitranslmed.3009318  0.353
2014 Giedt RJ, Sprachman MM, Yang KS, Weissleder R. Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates. Bioconjugate Chemistry. 25: 2081-5. PMID 25333750 DOI: 10.1021/Bc500433K  0.383
2014 Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P. Increased microvascularization and vessel permeability associate with active inflammation in human atheromata. Circulation. Cardiovascular Imaging. 7: 920-9. PMID 25170063 DOI: 10.1161/Circimaging.114.002113  0.334
2014 Dubach JM, Vinegoni C, Weissleder R. Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging. Optics Letters. 39: 4482-5. PMID 25078208 DOI: 10.1364/Ol.39.004482  0.378
2014 Aguirre AD, Vinegoni C, Sebas M, Weissleder R. Intravital imaging of cardiac function at the single-cell level. Proceedings of the National Academy of Sciences of the United States of America. 111: 11257-62. PMID 25053815 DOI: 10.1073/Pnas.1401316111  0.354
2014 Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R. Ultrafluorogenic coumarin-tetrazine probes for real-time biological imaging. Angewandte Chemie (International Ed. in English). 53: 7531-4. PMID 24915832 DOI: 10.1002/Anie.201403890  0.392
2014 Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R. In vivo imaging of specific drug-target binding at subcellular resolution. Nature Communications. 5: 3946. PMID 24867710 DOI: 10.1038/Ncomms4946  0.375
2014 Turetsky A, Kim E, Kohler RH, Miller MA, Weissleder R. Single cell imaging of Bruton's Tyrosine Kinase using an irreversible inhibitor Scientific Reports. 4. PMID 24759210 DOI: 10.1038/Srep04782  0.405
2014 Lee S, Vinegoni C, Sebas M, Weissleder R. Automated motion artifact removal for intravital microscopy, without a priori information. Scientific Reports. 4: 4507. PMID 24676021 DOI: 10.1038/Srep04507  0.357
2014 Kim E, Yang KS, Giedt RJ, Weissleder R. Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chemical Communications (Cambridge, England). 50: 4504-7. PMID 24663433 DOI: 10.1039/C4Cc00144C  0.316
2014 Elman JS, Murray RC, Murray RM, Wang F, Shen K, Gao S, Conway KE, Yarmush ML, Tannous BA, Weissleder R, Parekkadan B. Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells. Plos One. 9: e89882. PMID 24587097 DOI: 10.1371/Journal.Pone.0089882  0.311
2014 Thurber GM, Reiner T, Yang KS, Kohler RH, Weissleder R. Effect of small-molecule modification on single-cell pharmacokinetics of PARP inhibitors. Molecular Cancer Therapeutics. 13: 986-95. PMID 24552776 DOI: 10.1158/1535-7163.Mct-13-0801  0.345
2014 Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R. Platinum compounds for high-resolution in vivo cancer imaging. Chemmedchem. 9: 1131-5. PMID 24504646 DOI: 10.1002/Cmdc.201300502  0.377
2014 Weissleder R, Nahrendorf M, Pittet MJ. Imaging macrophages with nanoparticles. Nature Materials. 13: 125-38. PMID 24452356 DOI: 10.1038/Nmat3780  0.389
2014 Ullal AV, Peterson V, Agasti SS, Tuang S, Juric D, Castro CM, Weissleder R. Cancer cell profiling by barcoding allows multiplexed protein analysis in fine-needle aspirates. Science Translational Medicine. 6: 219ra9. PMID 24431113 DOI: 10.1126/Scitranslmed.3007361  0.325
2014 Castro CM, Ghazani AA, Chung J, Shao H, Issadore D, Yoon TJ, Weissleder R, Lee H. Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells. Lab On a Chip. 14: 14-23. PMID 23835814 DOI: 10.1039/C3Lc50621E  0.327
2014 Abazari A, Meimetis L, Moore D, Hand S, Weissleder R, Toner M. C-1005 Cryobiology. 69: 513. DOI: 10.1016/J.Cryobiol.2014.09.334  0.309
2013 Chung J, Issadore D, Ullal A, Lee K, Weissleder R, Lee H. Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip. Biomicrofluidics. 7: 54107. PMID 24404070 DOI: 10.1063/1.4821923  0.315
2013 Peterson VM, Castro CM, Chung J, Miller NC, Ullal AV, Castano MD, Penson RT, Lee H, Birrer MJ, Weissleder R. Ascites analysis by a microfluidic chip allows tumor-cell profiling. Proceedings of the National Academy of Sciences of the United States of America. 110: E4978-86. PMID 24297935 DOI: 10.1073/Pnas.1315370110  0.331
2013 Kim E, Yang KS, Weissleder R. Bioorthogonal small molecule imaging agents allow single-cell imaging of MET. Plos One. 8: e81275. PMID 24265843 DOI: 10.1371/Journal.Pone.0081275  0.369
2013 Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R. Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging. Biomedical Optics Express. 4: 2095-106. PMID 24156067 DOI: 10.1364/Boe.4.002095  0.331
2013 Yang KS, Budin G, Tassa C, Kister O, Weissleder R. Bioorthogonal approach to identify unsuspected drug targets in live cells. Angewandte Chemie (International Ed. in English). 52: 10593-7. PMID 23960025 DOI: 10.1002/Anie.201304096  0.314
2013 Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R. Targeting cathepsin E in pancreatic cancer by a small molecule allows in vivo detection. Neoplasia (New York, N.Y.). 15: 684-93. PMID 23814481 DOI: 10.1593/Neo.13276  0.326
2013 Zeglis BM, Sevak KK, Reiner T, Mohindra P, Carlin SD, Zanzonico P, Weissleder R, Lewis JS. A pretargeted PET imaging strategy based on bioorthogonal Diels-Alder click chemistry. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 1389-96. PMID 23708196 DOI: 10.2967/Jnumed.112.115840  0.351
2013 Majmudar MD, Keliher EJ, Heidt T, Leuschner F, Truelove J, Sena BF, Gorbatov R, Iwamoto Y, Dutta P, Wojtkiewicz G, Courties G, Sebas M, Borodovsky A, Fitzgerald K, Nolte MW, ... ... Weissleder R, et al. Monocyte-directed RNAi targeting CCR2 improves infarct healing in atherosclerosis-prone mice. Circulation. 127: 2038-46. PMID 23616627 DOI: 10.1161/Circulationaha.112.000116  0.311
2013 Shan G, Weissleder R, Hilderbrand SA. Upconverting organic dye doped core-shell nano-composites for dual-modality NIR imaging and photo-thermal therapy. Theranostics. 3: 267-74. PMID 23606913 DOI: 10.7150/Thno.5226  0.338
2013 Giedt RJ, Koch PD, Weissleder R. Single cell analysis of drug distribution by intravital imaging. Plos One. 8: e60988. PMID 23593370 DOI: 10.1371/Journal.Pone.0060988  0.379
2013 Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA. Fluorescence endoscopy of cathepsin activity discriminates dysplasia from colitis. Inflammatory Bowel Diseases. 19: 1339-45. PMID 23591598 DOI: 10.1097/Mib.0B013E318281F3F8  0.364
2013 Ghazani AA, McDermott S, Pectasides M, Sebas M, Mino-Kenudson M, Lee H, Weissleder R, Castro CM. Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and a miniaturized micro-NMR system. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 1009-17. PMID 23570873 DOI: 10.1016/J.Nano.2013.03.011  0.346
2013 Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R. Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo. Nature Communications. 4: 1504. PMID 23422672 DOI: 10.1038/Ncomms2506  0.362
2013 Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, ... ... Weissleder R, et al. Angiotensin II drives the production of tumor-promoting macrophages. Immunity. 38: 296-308. PMID 23333075 DOI: 10.1016/J.Immuni.2012.10.015  0.314
2013 Majmudar MD, Yoo J, Keliher EJ, Truelove JJ, Iwamoto Y, Sena B, Dutta P, Borodovsky A, Fitzgerald K, Di Carli MF, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M. Polymeric nanoparticle PET/MR imaging allows macrophage detection in atherosclerotic plaques. Circulation Research. 112: 755-61. PMID 23300273 DOI: 10.1161/Circresaha.111.300576  0.363
2013 Lee S, Vinegoni C, Feruglio PF, Weissleder R. Improved intravital microscopy via synchronization of respiration and holder stabilization. Journal of Biomedical Optics. 17: 96018-1. PMID 23085919 DOI: 10.1117/1.Jbo.17.9.096018  0.359
2013 Agasti SS, Kohler RH, Liong M, Peterson VM, Lee H, Weissleder R. Dual imaging and photoactivated nanoprobe for controlled cell tracking. Small (Weinheim An Der Bergstrasse, Germany). 9: 222-7. PMID 22996932 DOI: 10.1002/Smll.201201007  0.354
2013 Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivoravov M, Sbarbati A, Nahrendorf M, Weissleder R. Real-time in vivo imaging of the beating mouse heart at microscopic resolution. Nature Communications. 3: 1054. PMID 22968700 DOI: 10.1038/Ncomms2060  0.374
2013 Florian S, Chittajallu DR, Kohler RH, Orth JD, Sorger PK, Weissleder R, Danuser G, Mitchison TJ. Abstract A297: Microtubule targeting antimitotic drugs induce a lower mitotic arrest than clinically less effective antimitotic Eg5 inhibitors in mouse xenografts. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A297  0.306
2012 Keliher EJ, Reiner T, Thurber GM, Upadhyay R, Weissleder R. Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells. Chemistryopen. 1: 177-183. PMID 23997998 DOI: 10.1002/Open.201200014  0.352
2012 Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, ... ... Weissleder R, et al. Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Molecular Therapy. Nucleic Acids. 1: e4. PMID 23344621 DOI: 10.1038/Mtna.2011.3  0.344
2012 Chung J, Shao H, Reiner T, Issadore D, Weissleder R, Lee H. Microfluidic cell sorter (μFCS) for on-chip capture and analysis of single cells. Advanced Healthcare Materials. 1: 432-6. PMID 23184773 DOI: 10.1002/Adhm.201200046  0.336
2012 Chen JW, Figueiredo JL, Wojtkiewicz GR, Siegel C, Iwamoto Y, Kim DE, Nolte MW, Dickneite G, Weissleder R, Nahrendorf M. Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway. Jacc. Cardiovascular Imaging. 5: 1127-38. PMID 23153913 DOI: 10.1016/J.Jcmg.2012.01.025  0.347
2012 Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, et al. Implantable microenvironments to attract hematopoietic stem/cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 109: 19638-43. PMID 23150542 DOI: 10.1073/Pnas.1208384109  0.327
2012 Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, Hochberg FH, Breakefield XO, Weissleder R, Lee H. Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy. Nature Medicine. 18: 1835-40. PMID 23142818 DOI: 10.1038/Nm.2994  0.355
2012 Ripplinger CM, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA. Inflammation modulates murine venous thrombosis resolution in vivo: assessment by multimodal fluorescence molecular imaging. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2616-24. PMID 22995524 DOI: 10.1161/Atvbaha.112.251983  0.36
2012 Feruglio PF, Vinegoni C, Fexon L, Thurber G, Sbarbati A, Weissleder R. Noise suppressed, multifocus image fusion for enhanced intraoperative navigation. Journal of Biophotonics. 6: 363-70. PMID 22887724 DOI: 10.1002/Jbio.201200086  0.342
2012 Issadore D, Chung J, Shao H, Liong M, Ghazani AA, Castro CM, Weissleder R, Lee H. Ultrasensitive clinical enumeration of rare cells ex vivo using a micro-hall detector. Science Translational Medicine. 4: 141ra92. PMID 22764208 DOI: 10.1126/Scitranslmed.3003747  0.345
2012 Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY. On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics. Lab On a Chip. 12: 3103-10. PMID 22760641 DOI: 10.1039/C2Lc40337D  0.3
2012 Ghazani AA, Castro CM, Gorbatov R, Lee H, Weissleder R. Sensitive and direct detection of circulating tumor cells by multimarker µ-nuclear magnetic resonance. Neoplasia (New York, N.Y.). 14: 388-95. PMID 22745585 DOI: 10.1596/Neo.12696  0.336
2012 Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA. Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence. Jacc. Cardiovascular Imaging. 5: 607-15. PMID 22698530 DOI: 10.1016/J.Jcmg.2012.01.017  0.389
2012 Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R. Bioorthogonal imaging of aurora kinase A in live cells. Angewandte Chemie (International Ed. in English). 51: 6598-603. PMID 22644700 DOI: 10.1002/Anie.201200994  0.357
2012 Vinegoni C, Fumene Feruglio P, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R. Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography. Plos One. 7: e34427. PMID 22509302 DOI: 10.1371/Journal.Pone.0034427  0.312
2012 Earley S, Vinegoni C, Dunham J, Gorbatov R, Feruglio PF, Weissleder R. In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single-cell resolution. Cancer Research. 72: 2949-56. PMID 22505651 DOI: 10.1158/0008-5472.Can-11-4096  0.369
2012 Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R. Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents. Neoplasia (New York, N.Y.). 14: 169-77. PMID 22496617 DOI: 10.1593/Neo.12414  0.377
2012 Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R. Synthesis of [18F]BODIPY: bifunctional reporter for hybrid optical/positron emission tomography imaging. Angewandte Chemie (International Ed. in English). 51: 4603-6. PMID 22473535 DOI: 10.1002/Anie.201107957  0.371
2012 Forghani R, Wojtkiewicz GR, Zhang Y, Seeburg D, Bautz BR, Pulli B, Milewski AR, Atkinson WL, Iwamoto Y, Zhang ER, Etzrodt M, Rodriguez E, Robbins CS, Swirski FK, Weissleder R, et al. Demyelinating diseases: myeloperoxidase as an imaging biomarker and therapeutic target. Radiology. 263: 451-60. PMID 22438365 DOI: 10.1148/Radiol.12111593  0.322
2012 Peterson VM, Castro CM, Lee H, Weissleder R. Orthogonal amplification of nanoparticles for improved diagnostic sensing. Acs Nano. 6: 3506-13. PMID 22424443 DOI: 10.1021/Nn300536Y  0.314
2012 Devaraj NK, Thurber GM, Keliher EJ, Marinelli B, Weissleder R. Reactive polymer enables efficient in vivo bioorthogonal chemistry. Proceedings of the National Academy of Sciences of the United States of America. 109: 4762-7. PMID 22411831 DOI: 10.1073/Pnas.1113466109  0.322
2012 Niers JM, Chen JW, Lewandrowski G, Kerami M, Garanger E, Wojtkiewicz G, Waterman P, Keliher E, Weissleder R, Tannous BA. Single reporter for targeted multimodal in vivo imaging Journal of the American Chemical Society. 134: 5149-5156. PMID 22397453 DOI: 10.1021/Ja209868G  0.424
2012 Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, ... ... Weissleder R, et al. Origins of tumor-associated macrophages and neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 109: 2491-6. PMID 22308361 DOI: 10.1073/Pnas.1113744109  0.329
2012 Shao H, Min C, Issadore D, Liong M, Yoon TJ, Weissleder R, Lee H. Magnetic Nanoparticles and microNMR for Diagnostic Applications. Theranostics. 2: 55-65. PMID 22272219 DOI: 10.7150/Thno.3465  0.327
2012 Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, Dutta P, Iwamoto Y, Ueno T, Begieneman MP, Niessen HW, Piek JJ, Vinegoni C, Pittet MJ, Swirski FK, ... ... Weissleder R, et al. PET/MRI of inflammation in myocardial infarction. Journal of the American College of Cardiology. 59: 153-63. PMID 22222080 DOI: 10.1016/J.Jacc.2011.08.066  0.316
2012 Karver MR, Weissleder R, Hilderbrand SA. Bioorthogonal reaction pairs enable simultaneous, selective, multi-target imaging. Angewandte Chemie (International Ed. in English). 51: 920-2. PMID 22162316 DOI: 10.1002/Anie.201104389  0.331
2012 Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R. Supramolecular host-guest interaction for labeling and detection of cellular biomarkers. Angewandte Chemie (International Ed. in English). 51: 450-4. PMID 22113923 DOI: 10.1002/Anie.201105670  0.307
2012 Su HS, Nahrendorf M, Panizzi P, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW. Vasculitis: molecular imaging by targeting the inflammatory enzyme myeloperoxidase. Radiology. 262: 181-90. PMID 22084204 DOI: 10.1148/Radiol.11110040  0.677
2012 Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 37-45. PMID 21915104 DOI: 10.1038/Mt.2011.187  0.34
2012 Ntziachristos V, Weissleder R. Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Optics Letters. 26: 893-5. PMID 18040483 DOI: 10.1364/Ol.26.000893  0.331
2012 Ntziachristos V, Ripoll J, Weissleder R. Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Errata. Optics Letters. 27: 1652. PMID 18026531 DOI: 10.1364/Ol.27.001652  0.321
2012 Yang K, Thurber G, Reiner T, Kohler R, Weissleder R. Abstract 4293: In vivo imaging and tracking of a PARP inhibitor at single-cell resolution Cancer Research. 72: 4293-4293. DOI: 10.1158/1538-7445.Am2012-4293  0.336
2012 Kuhn HE, Orth J, Weissleder R, Mitchison T. Abstract 405: Innate immunity in taxol-mediated tumor regression Cancer Research. 72: 405-405. DOI: 10.1158/1538-7445.Am2012-405  0.326
2012 Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R. Abstract 1968: Nanoparticle mediated measurement of target-drug binding in cancer cells Cancer Research. 72: 1968-1968. DOI: 10.1158/1538-7445.Am2012-1968  0.334
2011 Thomas S, Waterman P, Chen S, Marinelli B, Seaman M, Rodig S, Ross RW, Josephson L, Weissleder R, Kelly KA. Development of Secreted Protein and Acidic and Rich in Cysteine (SPARC) Targeted Nanoparticles for the Prognostic Molecular Imaging of Metastatic Prostate Cancer. Journal of Nanomedicine & Nanotechnology. 2. PMID 22319675 DOI: 10.4172/2157-7439.1000112  0.351
2011 Keliher EJ, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet MJ, Weissleder R. 89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging. Bioconjugate Chemistry. 22: 2383-9. PMID 22035047 DOI: 10.1021/Bc200405D  0.413
2011 Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, ... ... Weissleder R, et al. Therapeutic siRNA silencing in inflammatory monocytes in mice. Nature Biotechnology. 29: 1005-10. PMID 21983520 DOI: 10.1038/Nbt.1989  0.315
2011 Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R. Nanoparticle-mediated measurement of target-drug binding in cancer cells. Acs Nano. 5: 9216-24. PMID 21962084 DOI: 10.1021/Nn203450P  0.329
2011 Yoon TJ, Lee H, Shao H, Hilderbrand SA, Weissleder R. Multicore assemblies potentiate magnetic properties of biomagnetic nanoparticles. Advanced Materials (Deerfield Beach, Fla.). 23: 4793-7. PMID 21953810 DOI: 10.1002/Adma.201102948  0.322
2011 Karver MR, Weissleder R, Hilderbrand SA. Synthesis and evaluation of a series of 1,2,4,5-tetrazines for bioorthogonal conjugation. Bioconjugate Chemistry. 22: 2263-70. PMID 21950520 DOI: 10.1021/Bc200295Y  0.301
2011 Budin G, Yang KS, Reiner T, Weissleder R. Bioorthogonal probes for polo-like kinase 1 imaging and quantification. Angewandte Chemie (International Ed. in English). 50: 9378-81. PMID 21948435 DOI: 10.1002/Anie.201103273  0.386
2011 Thurber GM, Weissleder R. A systems approach for tumor pharmacokinetics. Plos One. 6: e24696. PMID 21935441 DOI: 10.1371/Journal.Pone.0024696  0.339
2011 Panizzi P, Nahrendorf M, Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, ... ... Weissleder R, et al. In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation. Nature Medicine. 17: 1142-6. PMID 21857652 DOI: 10.1038/Nm.2423  0.305
2011 Liong M, Tassa C, Shaw SY, Lee H, Weissleder R. Multiplexed magnetic labeling amplification using oligonucleotide hybridization. Advanced Materials (Deerfield Beach, Fla.). 23: H254-7. PMID 21780311 DOI: 10.1002/Adma.201101401  0.325
2011 Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R. Accurate measurement of pancreatic islet beta-cell mass using a second-generation fluorescent exendin-4 analog. Proceedings of the National Academy of Sciences of the United States of America. 108: 12815-20. PMID 21768367 DOI: 10.1073/Pnas.1109859108  0.356
2011 Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ. Analysis of mitosis and antimitotic drug responses in tumors by in vivo microscopy and single-cell pharmacodynamics. Cancer Research. 71: 4608-16. PMID 21712408 DOI: 10.1158/0008-5472.Can-11-0412  0.345
2011 Jaffer FA, Calfon MA, Rosenthal A, Mallas G, Razansky RN, Mauskapf A, Weissleder R, Libby P, Ntziachristos V. Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury. Journal of the American College of Cardiology. 57: 2516-26. PMID 21679853 DOI: 10.1016/J.Jacc.2011.02.036  0.33
2011 Tassa C, Shaw SY, Weissleder R. Dextran-coated iron oxide nanoparticles: a versatile platform for targeted molecular imaging, molecular diagnostics, and therapy. Accounts of Chemical Research. 44: 842-52. PMID 21661727 DOI: 10.1021/Ar200084X  0.367
2011 Devaraj NK, Weissleder R. Biomedical applications of tetrazine cycloadditions. Accounts of Chemical Research. 44: 816-27. PMID 21627112 DOI: 10.1021/Ar200037T  0.397
2011 Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA. Indocyanine green enables near-infrared fluorescence imaging of lipid-rich, inflamed atherosclerotic plaques Science Translational Medicine. 3. PMID 21613624 DOI: 10.1126/Scitranslmed.3001577  0.382
2011 Buxton DB, Antman M, Danthi N, Dilsizian V, Fayad ZA, Garcia MJ, Jaff MR, Klimas M, Libby P, Nahrendorf M, Sinusas AJ, Wickline SA, Wu JC, Bonow RO, Weissleder R. Report of the National Heart, Lung, and Blood Institute working group on the translation of cardiovascular molecular imaging. Circulation. 123: 2157-63. PMID 21576680 DOI: 10.1161/Circulationaha.110.000943  0.374
2011 Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4484-93. PMID 21558403 DOI: 10.1158/1078-0432.Ccr-11-0575  0.371
2011 Deliolanis NC, Wurdinger T, Pike L, Tannous BA, Breakefield XO, Weissleder R, Ntziachristos V. In vivo tomographic imaging of red-shifted fluorescent proteins. Biomedical Optics Express. 2: 887-900. PMID 21483611 DOI: 10.1364/Boe.2.000887  0.36
2011 Haun JB, Yoon TJ, Lee H, Weissleder R. Molecular detection of biomarkers and cells using magnetic nanoparticles and diagnostic magnetic resonance. Methods in Molecular Biology (Clifton, N.J.). 726: 33-49. PMID 21424441 DOI: 10.1007/978-1-61779-052-2_3  0.341
2011 Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R. High-yielding, two-step 18F labeling strategy for 18F-PARP1 inhibitors. Chemmedchem. 6: 424-7. PMID 21360818 DOI: 10.1002/Cmdc.201000426  0.336
2011 Haun JB, Devaraj NK, Marinelli BS, Lee H, Weissleder R. Probing intracellular biomarkers and mediators of cell activation using nanosensors and bioorthogonal chemistry. Acs Nano. 5: 3204-13. PMID 21351804 DOI: 10.1021/Nn200333M  0.34
2011 Haun JB, Castro CM, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R. Micro-NMR for rapid molecular analysis of human tumor samples. Science Translational Medicine. 3: 71ra16. PMID 21346169 DOI: 10.1126/Scitranslmed.3002048  0.343
2011 Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R. Synthesis and in vivo imaging of a 18F-labeled PARP1 inhibitor using a chemically orthogonal scavenger-assisted high-performance method. Angewandte Chemie (International Ed. in English). 50: 1922-5. PMID 21328671 DOI: 10.1002/Anie.201006579  0.337
2011 Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robbins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R. Detection of macrophages in aortic aneurysms by nanoparticle positron emission tomography-computed tomography. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 750-7. PMID 21252070 DOI: 10.1161/Atvbaha.110.221499  0.308
2011 Quillard T, Croce K, Jaffer FA, Weissleder R, Libby P. Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo. Thrombosis and Haemostasis. 105: 828-36. PMID 21225096 DOI: 10.1160/Th10-09-0589  0.378
2011 Niers JM, Chen JW, Weissleder R, Tannous BA. Enhanced in vivo imaging of metabolically biotinylated cell surface reporters. Analytical Chemistry. 83: 994-9. PMID 21214190 DOI: 10.1021/Ac102758M  0.366
2011 Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R. Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. The Journal of Clinical Investigation. 121: 442-5. PMID 21123946 DOI: 10.1172/Jci44339  0.335
2011 Parekkadan B, Upadhyay R, Dunham J, Iwamoto Y, Mizoguchi E, Mizoguchi A, Weissleder R, Yarmush ML. Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes. Gastroenterology. 140: 966-75. PMID 20955701 DOI: 10.1053/J.Gastro.2010.10.013  0.301
2011 Thurber GM, Figueiredo JL, Weissleder R. Detection limits of intraoperative near infrared imaging for tumor resection. Journal of Surgical Oncology. 102: 758-64. PMID 20872807 DOI: 10.1002/Jso.21735  0.367
2011 Thurber GM, Weissleder R. Quantitating antibody uptake in vivo: conditional dependence on antigen expression levels. Molecular Imaging and Biology. 13: 623-32. PMID 20809210 DOI: 10.1007/S11307-010-0397-7  0.306
2011 Guimaraes AR, Ross R, Figuereido JL, Waterman P, Weissleder R. MRI with magnetic nanoparticles monitors downstream anti-angiogenic effects of mTOR inhibition Molecular Imaging and Biology. 13: 314-320. PMID 20559742 DOI: 10.1007/S11307-010-0357-2  0.307
2010 Shao H, Yoon TJ, Liong M, Weissleder R, Lee H. Magnetic nanoparticles for biomedical NMR-based diagnostics. Beilstein Journal of Nanotechnology. 1: 142-54. PMID 21977404 DOI: 10.3762/Bjnano.1.17  0.316
2010 Reiner T, Earley S, Turetsky A, Weissleder R. Bioorthogonal small-molecule ligands for PARP1 imaging in living cells. Chembiochem : a European Journal of Chemical Biology. 11: 2374-7. PMID 20967817 DOI: 10.1002/Cbic.201000477  0.351
2010 Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M. High-resolution magnetic resonance imaging enhanced with superparamagnetic nanoparticles measures macrophage burden in atherosclerosis. Circulation. 122: 1707-15. PMID 20937980 DOI: 10.1161/Circulationaha.109.891804  0.35
2010 Condeelis J, Weissleder R. In vivo imaging in cancer. Cold Spring Harbor Perspectives in Biology. 2: a003848. PMID 20861158 DOI: 10.1101/Cshperspect.A003848  0.398
2010 McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R. Targeted nanoagents for the detection of cancers. Molecular Oncology. 4: 511-28. PMID 20851695 DOI: 10.1016/J.Molonc.2010.08.003  0.328
2010 McCarthy JR, Korngold E, Weissleder R, Jaffer FA. A light-activated theranostic nanoagent for targeted macrophage ablation in inflammatory atherosclerosis. Small (Weinheim An Der Bergstrasse, Germany). 6: 2041-9. PMID 20721949 DOI: 10.1002/Smll.201000596  0.35
2010 Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA. Pioglitazone suppresses inflammation in vivo in murine carotid atherosclerosis: novel detection by dual-target fluorescence molecular imaging. Arteriosclerosis, Thrombosis, and Vascular Biology. 30: 1933-9. PMID 20689078 DOI: 10.1161/Atvbaha.110.206342  0.37
2010 Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R. Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection. Nature Nanotechnology. 5: 660-5. PMID 20676091 DOI: 10.1038/Nnano.2010.148  0.312
2010 Reiner T, Kohler RH, Liew CW, Hill JA, Gaglia J, Kulkarni RN, Weissleder R. Near-infrared fluorescent probe for imaging of pancreatic beta cells. Bioconjugate Chemistry. 21: 1362-8. PMID 20583828 DOI: 10.1021/Bc100184W  0.4
2010 Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M. Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice Journal of Clinical Investigation. 120: 2627-2634. PMID 20577051 DOI: 10.1172/Jci42304  0.335
2010 Libby P, DiCarli M, Weissleder R. The vascular biology of atherosclerosis and imaging targets. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 33S-37S. PMID 20395349 DOI: 10.2967/Jnumed.109.069633  0.354
2010 Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG. Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models. Plos One. 5: e10032. PMID 20386609 DOI: 10.1371/Journal.Pone.0010032  0.356
2010 Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R. Hybrid PET-optical imaging using targeted probes Proceedings of the National Academy of Sciences of the United States of America. 107: 7910-7915. PMID 20385821 DOI: 10.1073/Pnas.0915163107  0.375
2010 Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M. Impaired Infarct Healing in Atherosclerotic Mice With Ly-6Chi Monocytosis Journal of the American College of Cardiology. 55: 1629-1638. PMID 20378083 DOI: 10.1016/J.Jacc.2009.08.089  0.305
2010 Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R. Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography. Optics Letters. 35: 1088-90. PMID 20364226 DOI: 10.1364/Ol.35.001088  0.354
2010 Haun JB, Yoon TJ, Lee H, Weissleder R. Magnetic nanoparticle biosensors. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 2: 291-304. PMID 20336708 DOI: 10.1002/Wnan.84  0.322
2010 Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R. Bioorthogonal turn-on probes for imaging small molecules inside living cells. Angewandte Chemie (International Ed. in English). 49: 2869-72. PMID 20306505 DOI: 10.1002/Anie.200906120  0.376
2010 van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K. Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene. 29: 3185-95. PMID 20305695 DOI: 10.1038/Onc.2010.75  0.384
2010 Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T. Imaging primary lung cancers in mice to study radiation biology. International Journal of Radiation Oncology, Biology, Physics. 76: 973-7. PMID 20206017 DOI: 10.1016/J.Ijrobp.2009.11.038  0.305
2010 Hingtgen SD, Kasmieh R, van de Water J, Weissleder R, Shah K. A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy. Stem Cells (Dayton, Ohio). 28: 832-41. PMID 20127797 DOI: 10.1002/Stem.313  0.328
2010 Rodríguez E, Nilges M, Weissleder R, Chen JW. Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity. Journal of the American Chemical Society. 132: 168-77. PMID 19968300 DOI: 10.1021/Ja905274F  0.332
2010 Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B. Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1 Molecular Therapy. 18: 285-294. PMID 19844198 DOI: 10.1038/Mt.2009.232  0.314
2010 Martinez-Boubeta C, Balcells L, Cristòfol R, Sanfeliu C, Rodríguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martínez B. Self-assembled multifunctional Fe/MgO nanospheres for magnetic resonance imaging and hyperthermia Nanomedicine: Nanotechnology, Biology, and Medicine. 6: 362-370. PMID 19800988 DOI: 10.1016/J.Nano.2009.09.003  0.322
2010 Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer JE, Aikawa E. Intravital molecular imaging of small-diameter tissue-engineered vascular grafts in mice: a feasibility study. Tissue Engineering. Part C, Methods. 16: 597-607. PMID 19751103 DOI: 10.1089/Ten.Tec.2009.0466  0.38
2010 Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R. Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles. Optics Letters. 34: 2566-8. PMID 19724491 DOI: 10.1364/Ol.34.002566  0.363
2009 Kelly KA, Shaw SY, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R. Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 311-7. PMID 20023731 DOI: 10.1039/B821775K  0.425
2009 Thurber GM, Figueiredo JL, Weissleder R. Multicolor fluorescent intravital live microscopy (FILM) for surgical tumor resection in a mouse xenograft model. Plos One. 4: e8053. PMID 19956597 DOI: 10.1371/Journal.Pone.0008053  0.328
2009 Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A. Molecular MRI detects low levels of cardiomyocyte apoptosis in a transgenic model of chronic heart failure. Circulation. Cardiovascular Imaging. 2: 468-75. PMID 19920045 DOI: 10.1161/Circimaging.109.863779  0.327
2009 Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L. Molecular MRI of cardiomyocyte apoptosis with simultaneous delayed-enhancement MRI distinguishes apoptotic and necrotic myocytes in vivo: potential for midmyocardial salvage in acute ischemia. Circulation. Cardiovascular Imaging. 2: 460-7. PMID 19920044 DOI: 10.1161/Circimaging.109.859678  0.31
2009 Hilderbrand SA, Weissleder R. Near-infrared fluorescence: application to in vivo molecular imaging. Current Opinion in Chemical Biology. 14: 71-9. PMID 19879798 DOI: 10.1016/J.Cbpa.2009.09.029  0.402
2009 Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA. Oxazine conjugated nanoparticle detects in vivo hypochlorous acid and peroxynitrite generation Journal of the American Chemical Society. 131: 15739-15744. PMID 19817443 DOI: 10.1021/Ja903922U  0.358
2009 Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R. Fast and sensitive pretargeted labeling of cancer cells through a tetrazine/trans-cyclooctene cycloaddition. Angewandte Chemie (International Ed. in English). 48: 7013-6. PMID 19697389 DOI: 10.1002/Anie.200903233  0.348
2009 Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R. Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. Journal of Visualized Experiments : Jove. PMID 19696720 DOI: 10.3791/1510  0.374
2009 McCarthy JR, Bhaumik J, Merbouh N, Weissleder R. High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins. Organic & Biomolecular Chemistry. 7: 3430-6. PMID 19675897 DOI: 10.1039/B908713C  0.302
2009 Ronald JA, Chen JW, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK. Enzyme-sensitive magnetic resonance imaging targeting myeloperoxidase identifies active inflammation in experimental rabbit atherosclerotic plaques. Circulation. 120: 592-9. PMID 19652086 DOI: 10.1161/Circulationaha.108.813998  0.319
2009 Lee H, Yoon TJ, Figueiredo JL, Swirski FK, Weissleder R. Rapid detection and profiling of cancer cells in fine-needle aspirates. Proceedings of the National Academy of Sciences of the United States of America. 106: 12459-64. PMID 19620715 DOI: 10.1073/Pnas.0902365106  0.35
2009 Bhaumik J, Weissleder R, McCarthy JR. Synthesis and photophysical properties of sulfonamidophenyl porphyrins as models for activatable photosensitizers. The Journal of Organic Chemistry. 74: 5894-901. PMID 19610602 DOI: 10.1021/Jo900832Y  0.322
2009 Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R. Hybrid in vivo FMT-CT imaging of protease activity in atherosclerosis with customized nanosensors Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1444-1451. PMID 19608968 DOI: 10.1161/Atvbaha.109.193086  0.37
2009 Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R. Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chemical Communications (Cambridge, England). 4188-90. PMID 19585016 DOI: 10.1039/B905927J  0.328
2009 Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R. Born normalization for fluorescence optical projection tomography for whole heart imaging. Journal of Visualized Experiments : Jove. PMID 19578329 DOI: 10.3791/1389  0.32
2009 Rajendran R, Ronald JA, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F. Nuclear microscopy: a novel technique for quantitative imaging of gadolinium distribution within tissue sections. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 15: 338-44. PMID 19575834 DOI: 10.1017/S1431927609090813  0.332
2009 Wildgruber M, Lee H, Chudnovskiy A, Yoon TJ, Etzrodt M, Pittet MJ, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski FK. Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors. Plos One. 4: e5663. PMID 19461894 DOI: 10.1371/Journal.Pone.0005663  0.315
2009 McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA. Multimodal nanoagents for the detection of intravascular thrombi. Bioconjugate Chemistry. 20: 1251-5. PMID 19456115 DOI: 10.1021/Bc9001163  0.386
2009 Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ. Implantable diagnostic device for cancer monitoring Biosensors and Bioelectronics. 24: 3252-3257. PMID 19442510 DOI: 10.1016/J.Bios.2009.04.010  0.316
2009 Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton AP, Waterman P, Figueiredo JL, Kohler RH, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ. Behavior of endogenous Tumor-associated macrophages assessed in vivo using a functionalized nanoparticle Neoplasia. 11: 459-468. PMID 19412430 DOI: 10.1593/Neo.09356  0.424
2009 Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS. Genetically engineered T cells to target EGFRvIII expressing glioblastoma. Journal of Neuro-Oncology. 94: 373-82. PMID 19387557 DOI: 10.1007/S11060-009-9889-1  0.336
2009 Swirski FK, Weissleder R, Pittet MJ. Heterogeneous in vivo behavior of monocyte subsets in atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1424-32. PMID 19372462 DOI: 10.1161/Atvbaha.108.180521  0.342
2009 Jaffer FA, Libby P, Weissleder R. Optical and multimodality molecular imaging: insights into atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1017-24. PMID 19359659 DOI: 10.1161/Atvbaha.108.165530  0.373
2009 Christen T, Nahrendorf M, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P. Molecular imaging of innate immune cell function in transplant rejection Circulation. 119: 1925-1932. PMID 19332470 DOI: 10.1161/Circulationaha.108.796888  0.313
2009 Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. 106: 4822-7. PMID 19264968 DOI: 10.1073/Pnas.0806647106  0.342
2009 Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, García-Añoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO. Mutant sodium channel for tumor therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 810-9. PMID 19259066 DOI: 10.1038/Mt.2009.33  0.313
2009 Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A. Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proceedings of the National Academy of Sciences of the United States of America. 106: 2712-6. PMID 19196966 DOI: 10.1073/Pnas.0813314106  0.301
2009 McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW. Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy. Neuroimage. 45: 360-9. PMID 19154791 DOI: 10.1016/J.Neuroimage.2008.12.022  0.417
2009 Devaraj NK, Keliher EJ, Thurber GM, Nahrendorf M, Weissleder R. 18F labeled nanoparticles for in vivo PET-CT imaging. Bioconjugate Chemistry. 20: 397-401. PMID 19138113 DOI: 10.1021/Bc8004649  0.304
2009 Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U. Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecologic Oncology. 112: 616-22. PMID 19135233 DOI: 10.1016/J.Ygyno.2008.11.018  0.389
2009 Shao F, Weissleder R, Hilderbrand SA. Monofunctional carbocyanine dyes for bio- and bioorthogonal conjugation. Bioconjugate Chemistry. 19: 2487-91. PMID 19053316 DOI: 10.1021/Bc800417B  0.303
2009 Sosnovik DE, Nahrendorf M, Weissleder R. Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Research in Cardiology. 103: 122-30. PMID 18324368 DOI: 10.1007/S00395-008-0710-7  0.375
2009 Nahrendorf M, Sosnovik DE, Weissleder R. MR-optical imaging of cardiovascular molecular targets. Basic Research in Cardiology. 103: 87-94. PMID 18324364 DOI: 10.1007/S00395-008-0707-2  0.397
2009 Chang K, Francis S, Aikawa E, Figueiredo J, Patel P, Weissleder R, Plutzky J, Jaffer F. Abstract: P640 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-Γ ACTIVATION REDUCES INFLAMMATION IN ATHEROSCLEROSIS AS ASSESSED BY SERIAL IN VIVO FLUORESCENCE MOLECULAR IMAGING Atherosclerosis Supplements. 10: e826. DOI: 10.1016/S1567-5688(09)70808-6  0.345
2009 Christen T, Nahrendorf M, Wildgruber M, Swirski F, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P. Abstract: 611 MACROPHAGE IMAGING IN GRAFT REJECTION Atherosclerosis Supplements. 10. DOI: 10.1016/S1567-5688(09)70358-7  0.302
2009 Taboada E, Solanas R, Rodríguez E, Weissleder R, Roig A. Supercritical-Fluid-Assisted One-Pot Synthesis of Biocompatible Core(γ-Fe2O3)/Shell(SiO2) Nanoparticles as High RelaxivityT2-Contrast Agents for Magnetic Resonance Imaging Advanced Functional Materials. 19: 2319-2324. DOI: 10.1002/Adfm.200801681  0.322
2008 Salthouse CD, Weissleder R, Mahmood U. Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis. Ieee Transactions On Biomedical Circuits and Systems. 2: 204-11. PMID 19830273 DOI: 10.1109/Tbcas.2008.2003195  0.324
2008 Salthouse C, Hildebrand S, Weissleder R, Mahmood U. Design and demonstration of a small-animal up-conversion imager. Optics Express. 16: 21731-7. PMID 19104605 DOI: 10.1364/Oe.16.021731  0.357
2008 Devaraj NK, Weissleder R, Hilderbrand SA. Tetrazine-based cycloadditions: application to pretargeted live cell imaging. Bioconjugate Chemistry. 19: 2297-9. PMID 19053305 DOI: 10.1021/Bc8004446  0.361
2008 Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ. Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation. The Journal of Clinical Investigation. 118: 4058-66. PMID 19033674 DOI: 10.1172/Jci36335  0.369
2008 Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V. Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. Proceedings of the National Academy of Sciences of the United States of America. 105: 19126-31. PMID 19015534 DOI: 10.1073/Pnas.0804798105  0.39
2008 Breckwoldt MO, Chen JW, Stangenberg L, Aikawa E, Rodriguez E, Qiu S, Moskowitz MA, Weissleder R. Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase. Proceedings of the National Academy of Sciences of the United States of America. 105: 18584-9. PMID 19011099 DOI: 10.1073/Pnas.0803945105  0.681
2008 Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K. Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Molecular Cancer Therapeutics. 7: 3575-85. PMID 19001440 DOI: 10.1158/1535-7163.Mct-08-0640  0.352
2008 Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP. Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model. Pancreas. 37: 440-4. PMID 18953259 DOI: 10.1097/Mpa.0B013E31817C5113  0.332
2008 Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, et al. Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6478-86. PMID 18927287 DOI: 10.1158/1078-0432.Ccr-08-1128  0.302
2008 Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R. Real-time catheter molecular sensing of inflammation in proteolytically active atherosclerosis. Circulation. 118: 1802-9. PMID 18852366 DOI: 10.1161/Circulationaha.108.785881  0.341
2008 Perez JM, Grimm J, Josephson L, Weissleder R. Integrated nanosensors to determine levels and functional activity of human telomerase. Neoplasia (New York, N.Y.). 10: 1066-72. PMID 18813356 DOI: 10.1593/Neo.08350  0.422
2008 Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schär M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M. Off-resonance angiography: a new method to depict vessels--phantom and rabbit studies. Radiology. 249: 501-9. PMID 18780823 DOI: 10.1148/Radiol.2491071706  0.306
2008 Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Ploegh HL, Plough HL, Barrett TA, Weissleder R, Khazaie K. Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. Plos One. 3: e2916. PMID 18698347 DOI: 10.1371/Journal.Pone.0002916  0.372
2008 Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schär M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M. Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using "positive contrast" magnetic resonance imaging. Journal of the American College of Cardiology. 52: 483-91. PMID 18672170 DOI: 10.1016/J.Jacc.2008.03.063  0.354
2008 Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U. Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy. Radiology. 248: 925-35. PMID 18647846 DOI: 10.1148/Radiol.2482071496  0.335
2008 Sosnovik DE, Nahrendorf M, Weissleder R. Targeted imaging of myocardial damage. Nature Clinical Practice. Cardiovascular Medicine. S63-70. PMID 18641609 DOI: 10.1038/Ncpcardio1115  0.389
2008 McCarthy JR, Weissleder R. Multifunctional magnetic nanoparticles for targeted imaging and therapy. Advanced Drug Delivery Reviews. 60: 1241-51. PMID 18508157 DOI: 10.1016/J.Addr.2008.03.014  0.355
2008 Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R. Perturbational profiling of nanomaterial biologic activity. Proceedings of the National Academy of Sciences of the United States of America. 105: 7387-92. PMID 18492802 DOI: 10.1073/Pnas.0802878105  0.321
2008 Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R. Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model Journal of Neuroscience. 28: 4406-4413. PMID 18434519 DOI: 10.1523/Jneurosci.0296-08.2008  0.36
2008 Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R. Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma. Plos Medicine. 5: e85. PMID 18416599 DOI: 10.1097/01.Mpa.0000297722.30876.7A  0.408
2008 Weissleder R, Pittet MJ. Imaging in the era of molecular oncology. Nature. 452: 580-9. PMID 18385732 DOI: 10.1038/Nature06917  0.362
2008 Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R. Detection of early prostate cancer using a hepsin-targeted imaging agent. Cancer Research. 68: 2286-91. PMID 18381435 DOI: 10.1158/0008-5472.Can-07-1349  0.326
2008 Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG. Pilot study evaluating use of lymphotrophic nanoparticle-enhanced magnetic resonance imaging for assessing lymph nodes in renal cell cancer. Urology. 71: 708-12. PMID 18295316 DOI: 10.1016/J.Urology.2007.11.096  0.316
2008 Nahrendorf M, Sosnovik D, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R. Activatable magnetic resonance imaging agent reports myeloperoxidase activity in healing infarcts and noninvasively detects the antiinflammatory effects of atorvastatin on ischemia-reperfusion injury. Circulation. 117: 1153-60. PMID 18268141 DOI: 10.1161/Circulationaha.107.756510  0.338
2008 Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R. Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis Brain. 131: 1123-1133. PMID 18234693 DOI: 10.1093/Brain/Awn004  0.683
2008 Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA. A secreted luciferase for ex vivo monitoring of in vivo processes. Nature Methods. 5: 171-3. PMID 18204457 DOI: 10.1038/Nmeth.1177  0.351
2008 Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik DE, Aikawa E, Libby P, Swirski FK, Weissleder R. Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis. Circulation. 117: 379-87. PMID 18158358 DOI: 10.1161/Circulationaha.107.741181  0.317
2008 Harisinghani M, Ross RW, Guimaraes AR, Weissleder R. Utility of a new bolus-injectable nanoparticle for clinical cancer staging. Neoplasia (New York, N.Y.). 9: 1160-5. PMID 18084623 DOI: 10.1593/Neo.07940  0.315
2008 Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE. Noninvasive imaging of apoptosis in cardiovascular disease. Heart Failure Reviews. 13: 163-73. PMID 18074226 DOI: 10.1007/S10741-007-9068-4  0.363
2008 Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA. A highly selective fluorescent probe for thiol bioimaging. Organic Letters. 10: 37-40. PMID 18062694 DOI: 10.1021/Ol702539V  0.327
2008 Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L. Fate of a bioactive fluorescent wortmannin derivative in cells. Bioconjugate Chemistry. 19: 130-7. PMID 17988080 DOI: 10.1021/Bc7002204  0.321
2008 Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE. Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging Nmr in Biomedicine. 21: 453-463. PMID 17918777 DOI: 10.1002/Nbm.1209  0.322
2008 Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U. In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe Translational Oncology. 1: 84-94. DOI: 10.1593/Tlo.08118  0.361
2008 Deliolanis N, Wurdinger T, Tannous BA, Shah K, Ntziachristos V, Weissleder R. Comparison of the Fluorescent Protein Performance in Deep-Tissue Small-Animal Imaging Applications Ieee Transactions On Biomedical Engineering. DOI: 10.1364/Biomed.2008.Pdpbtuf10  0.344
2008 Wang A, Guimaraes A, Zhang L, Gu F, Langer R, Weissleder R, Farokhzad O. Development of Novel Multifunctional Nanoparticles for Combined Imaging and Targeted Delivery of Chemoradiotherapy International Journal of Radiation Oncology*Biology*Physics. 72: S707. DOI: 10.1016/J.Ijrobp.2008.06.534  0.351
2007 Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K. Mast cells are an essential hematopoietic component for polyp development. Proceedings of the National Academy of Sciences of the United States of America. 104: 19977-82. PMID 18077429 DOI: 10.1073/Pnas.0704620104  0.319
2007 Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P. A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chemistry & Biology. 14: 1221-31. PMID 18022561 DOI: 10.1016/J.Chembiol.2007.10.005  0.383
2007 Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R. A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. Plos One. 2: e1075. PMID 17957257 DOI: 10.1371/Journal.Pone.0001075  0.413
2007 Upadhyay R, Sheth RA, Weissleder R, Mahmood U. Quantitative real-time catheter-based fluorescence molecular imaging in mice. Radiology. 245: 523-31. PMID 17940307 DOI: 10.1148/Radiol.2452061613  0.392
2007 Jaffer FA, Libby P, Weissleder R. Molecular imaging of cardiovascular disease. Circulation. 116: 1052-61. PMID 17724271 DOI: 10.1161/Circulationaha.106.647164  0.409
2007 McCarthy JR, Kelly KA, Sun EY, Weissleder R. Targeted delivery of multifunctional magnetic nanoparticles. Nanomedicine (London, England). 2: 153-67. PMID 17716118 DOI: 10.2217/17435889.2.2.153  0.388
2007 Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U. Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Molecular Imaging. 6: 269-76. PMID 17711782 DOI: 10.2310/7290.2007.00023  0.397
2007 Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U. Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment International Journal of Cancer. 121: 2492-2500. PMID 17683072 DOI: 10.1002/Ijc.22995  0.378
2007 Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, ... ... Weissleder R, et al. A spatially and temporally restricted mouse model of soft tissue sarcoma. Nature Medicine. 13: 992-7. PMID 17676052 DOI: 10.1038/Nm1602  0.318
2007 Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K. Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo Cancer Research. 67: 7335-7342. PMID 17671203 DOI: 10.1158/0008-5472.Can-07-0077  0.325
2007 Kim Y, Choi Y, Weissleder R, Tung CH. Membrane permeable esterase-activated fluorescent imaging probe. Bioorganic & Medicinal Chemistry Letters. 17: 5054-7. PMID 17664067 DOI: 10.1016/J.Bmcl.2007.07.026  0.351
2007 Kelly KA, Carson J, McCarthy JR, Weissleder R. Novel peptide sequence ("IQ-tag") with high affinity for NIR fluorochromes allows protein and cell specific labeling for in vivo imaging. Plos One. 2: e665. PMID 17653285 DOI: 10.1371/Journal.Pone.0000665  0.331
2007 Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk. The Journal of Experimental Medicine. 204: 1911-22. PMID 17646407 DOI: 10.1084/Jem.20070285  0.309
2007 Pittet MJ, Grimm J, Berger CR, Tamura T, Wojtkiewicz G, Nahrendorf M, Romero P, Swirski FK, Weissleder R. In vivo imaging of T cell delivery to tumors after adoptive transfer therapy. Proceedings of the National Academy of Sciences of the United States of America. 104: 12457-61. PMID 17640914 DOI: 10.1073/Pnas.0704460104  0.365
2007 Sheth RA, Upadhyay R, Weissleder R, Mahmood U. Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Molecular Imaging. 6: 147-55. PMID 17532881 DOI: 10.2310/7290.2007.00012  0.369
2007 Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U. Colonic adenocarcinomas: Near-infrared microcatheter imaging of smart probes for early detection - Study in mice Radiology. 244: 232-238. PMID 17507718 DOI: 10.1148/Radiol.2441052114  0.36
2007 Sosnovik DE, Nahrendorf M, Weissleder R. Molecular magnetic resonance imaging in cardiovascular medicine. Circulation. 115: 2076-86. PMID 17438163 DOI: 10.1161/Circulationaha.106.658930  0.358
2007 Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, Weissleder R. Optical visualization of cathepsin K activity in atherosclerosis with a novel, protease-activatable fluorescence sensor. Circulation. 115: 2292-8. PMID 17420353 DOI: 10.1161/Circulationaha.106.660340  0.32
2007 Nahrendorf M, Sosnovik DE, Waterman P, Swirski FK, Pande AN, Aikawa E, Figueiredo JL, Pittet MJ, Weissleder R. Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct. Circulation Research. 100: 1218-25. PMID 17379832 DOI: 10.1161/01.Res.0000265064.46075.31  0.375
2007 Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V. Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo. Circulation. 115: 1384-91. PMID 17339546 DOI: 10.1161/Circulationaha.106.663351  0.382
2007 Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R. Tomographic fluorescence imaging of tumor vascular volume in mice Radiology. 242: 751-758. PMID 17325064 DOI: 10.1148/Radiol.2423052065  0.386
2007 Nahrendorf M, Badea C, Hedlund LW, Figueiredo JL, Sosnovik DE, Johnson GA, Weissleder R. High-resolution imaging of murine myocardial infarction with delayed-enhancement cine micro-CT. American Journal of Physiology. Heart and Circulatory Physiology. 292: H3172-8. PMID 17322414 DOI: 10.1152/Ajpheart.01307.2006  0.326
2007 Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B. Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arthritis and Rheumatism. 56: 117-28. PMID 17195214 DOI: 10.1002/Art.22303  0.342
2007 Grimm J, Kircher MF, Weissleder R. [Cell tracking. Principles and applications]. Der Radiologe. 47: 25-33. PMID 17187264 DOI: 10.1007/S00117-006-1449-5  0.371
2007 Nahrendorf M, Weissleder R. [Advances in cardiovascular medicine through molecular imaging]. Der Radiologe. 47: 18-24. PMID 17187263 DOI: 10.1007/S00117-006-1450-Z  0.377
2007 Weissleder R, Imhof H. [Molecular imaging--a new emphasis in radiology]. Der Radiologe. 47: 6-7. PMID 17136404 DOI: 10.1007/S00117-006-1447-7  0.332
2007 Montet-Abou K, Montet X, Weissleder R, Josephson L. Cell Internalization of Magnetic Nanoparticles Using Transfection Agents Molecular Imaging. 6: 7290.2006.00028. DOI: 10.2310/7290.2006.00028  0.305
2006 Pittet MJ, Swirski FK, Reynolds F, Josephson L, Weissleder R. Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles. Nature Protocols. 1: 73-9. PMID 17406214 DOI: 10.1038/Nprot.2006.11  0.399
2006 Kelly KA, Waterman P, Weissleder R. In vivo imaging of molecularly targeted phage. Neoplasia (New York, N.Y.). 8: 1011-8. PMID 17217618 DOI: 10.1593/Neo.06610  0.422
2006 Sosnovik DE, Weissleder R. Emerging concepts in molecular MRI. Current Opinion in Biotechnology. 18: 4-10. PMID 17126545 DOI: 10.1016/J.Copbio.2006.11.001  0.4
2006 Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D. Neural stem cell transplant survival in brains of mice: assessing the effect of immunity and ischemia by using real-time bioluminescent imaging. Radiology. 241: 822-30. PMID 17114629 DOI: 10.1148/Radiol.2413050466  0.303
2006 Campanella GSV, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewkz GR, Weissleder R, Luster AD. Oligomerization of CXCL10 is necessary for endothelial cell presentation and in vivo activity Journal of Immunology. 177: 6991-6998. PMID 17082614 DOI: 10.4049/Jimmunol.177.10.6991  0.312
2006 Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R. Molecular imaging of myocardial infarction. Journal of Molecular and Cellular Cardiology. 41: 921-33. PMID 17067633 DOI: 10.1016/J.Yjmcc.2006.09.008  0.362
2006 Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R. Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis. Circulation. 114: 1504-11. PMID 17000904 DOI: 10.1161/Circulationaha.106.646380  0.404
2006 Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U. Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization Gastrointestinal Endoscopy. 64: 589-597. PMID 16996355 DOI: 10.1016/J.Gie.2006.02.048  0.401
2006 Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA. Cyclophosphamide increases transgene expression mediated by an oncolytic adenovirus in glioma-bearing mice monitored by bioluminescence imaging. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 779-88. PMID 16996314 DOI: 10.1016/J.Ymthe.2006.08.008  0.308
2006 Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL. In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia (New York, N.Y.). 8: 772-80. PMID 16984734 DOI: 10.1593/Neo.06331  0.325
2006 Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. Journal of Neurosurgery. 105: 445-54. PMID 16961141 DOI: 10.3171/Jns.2006.105.3.445  0.326
2006 Jaffer FA, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R. Cellular imaging of inflammation in atherosclerosis using magnetofluorescent nanomaterials. Molecular Imaging. 5: 85-92. PMID 16954022 DOI: 10.2310/7290.2006.00009  0.433
2006 Fulci G, Breymann L, Gianni D, Kurozomi K, Rhee SS, Yu J, Kaur B, Louis DN, Weissleder R, Caligiuri MA, Chiocca EA. Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 12873-8. PMID 16908838 DOI: 10.1073/Pnas.0605496103  0.317
2006 Choi Y, McCarthy JR, Weissleder R, Tung CH. Conjugation of a photosensitizer to an oligoarginine-based cell-penetrating peptide increases the efficacy of photodynamic therapy. Chemmedchem. 1: 458-63. PMID 16892381 DOI: 10.1002/Cmdc.200500036  0.3
2006 Montet X, Rajopadhye M, Weissleder R. An albumin-activated far-red fluorochrome for in vivo imaging. Chemmedchem. 1: 66-9. PMID 16892337 DOI: 10.1002/Cmdc.200500028  0.365
2006 Chen JW, Querol Sans M, Bogdanov A, Weissleder R. Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates. Radiology. 240: 473-81. PMID 16864673 DOI: 10.1148/Radiol.2402050994  0.368
2006 Galande AK, Hilderbrand SA, Weissleder R, Tung CH. Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core. Journal of Medicinal Chemistry. 49: 4715-20. PMID 16854078 DOI: 10.1021/Jm051001A  0.337
2006 Choi Y, Weissleder R, Tung CH. Selective antitumor effect of novel protease-mediated photodynamic agent. Cancer Research. 66: 7225-9. PMID 16849570 DOI: 10.1158/0008-5472.Can-06-0448  0.334
2006 Montet X, Weissleder R, Josephson L. Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas. Bioconjugate Chemistry. 17: 905-11. PMID 16848396 DOI: 10.1021/Bc060035+  0.371
2006 Hsiao JK, Law B, Weissleder R, Tung CH. In-vivo imaging of tumor associated urokinase-type plasminogen activator activity. Journal of Biomedical Optics. 11: 34013. PMID 16822063 DOI: 10.1117/1.2204029  0.376
2006 Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R. In vivo phage display selection yields atherosclerotic plaque targeted peptides for imaging. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 8: 201-7. PMID 16791746 DOI: 10.1007/S11307-006-0043-6  0.35
2006 Kelly KA, Clemons PA, Yu AM, Weissleder R. High-throughput identification of phage-derived imaging agents. Molecular Imaging. 5: 24-30. PMID 16779967 DOI: 10.2310/7290.2006.00003  0.303
2006 Tréhin R, Figueiredo JL, Pittet MJ, Weissleder R, Josephson L, Mahmood U. Fluorescent nanoparticle uptake for brain tumor visualization Neoplasia. 8: 302-311. PMID 16756722 DOI: 10.1593/Neo.05751  0.36
2006 Weissleder R. Molecular imaging in cancer. Science (New York, N.Y.). 312: 1168-71. PMID 16728630 DOI: 10.1126/Science.1125949  0.39
2006 Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK. N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption Molecular and Cellular Biology. 26: 4185-4200. PMID 16705170 DOI: 10.1128/Mcb.01055-05  0.303
2006 Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA. Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy. Journal of Biomedical Optics. 11: 021009. PMID 16674184 DOI: 10.1117/1.2186337  0.366
2006 Tannous BA, Grimm J, Perry KF, Chen JW, Weissleder R, Breakefield XO. Metabolic biotinylation of cell surface receptors for in vivo imaging. Nature Methods. 3: 391-6. PMID 16628210 DOI: 10.1038/Nmeth875  0.403
2006 Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L. Nanoparticle imaging of integrins on tumor cells. Neoplasia (New York, N.Y.). 8: 214-22. PMID 16611415 DOI: 10.1593/Neo.05769  0.375
2006 Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA. Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 599-609. PMID 16607378 DOI: 10.1038/Labinvest.3700421  0.35
2006 Jaffer FA, Libby P, Weissleder R. Molecular and cellular imaging of atherosclerosis: emerging applications. Journal of the American College of Cardiology. 47: 1328-38. PMID 16580517 DOI: 10.1016/J.Jacc.2006.01.029  0.363
2006 Quinti L, Weissleder R, Tung CH. A fluorescent nanosensor for apoptotic cells. Nano Letters. 6: 488-90. PMID 16522048 DOI: 10.1021/Nl0524694  0.323
2006 Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palù G, Irimia D, Toner M, Weissleder R, Poznansky MC. Murine B16 melanomas expressing high levels of the chemokine stromal-derived factor-1/CXCL12 induce tumor-specific T cell chemorepulsion and escape from immune control. Journal of Immunology (Baltimore, Md. : 1950). 176: 2902-14. PMID 16493048 DOI: 10.4049/Jimmunol.176.5.2902  0.321
2006 Rabin O, Manuel Perez J, Grimm J, Wojtkiewicz G, Weissleder R. An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nature Materials. 5: 118-22. PMID 16444262 DOI: 10.1038/Nmat1571  0.367
2006 Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nature Immunology. 7: 284-92. PMID 16444258 DOI: 10.1038/Ni1306  0.304
2006 Sun EY, Josephson L, Kelly KA, Weissleder R. Development of nanoparticle libraries for biosensing. Bioconjugate Chemistry. 17: 109-13. PMID 16417258 DOI: 10.1021/Bc050290E  0.324
2006 Messerli SM, Prabhakar S, Tang Y, Mahmood U, Giovannini M, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO. Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Human Gene Therapy. 17: 20-30. PMID 16409122 DOI: 10.1089/Hum.2006.17.20  0.312
2006 Figueiredo JL, Alencar H, Weissleder R, Mahmood U. Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer International Journal of Cancer. 118: 2672-2677. PMID 16380983 DOI: 10.1002/Ijc.21713  0.364
2006 Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R. Novel multiwavelength microscopic scanner for mouse imaging. Neoplasia (New York, N.Y.). 7: 977-83. PMID 16331883 DOI: 10.1593/Neo.05376  0.373
2006 Sosnovik D, Weissleder R. Magnetic resonance and fluorescence based molecular imaging technologies. Progress in Drug Research. Fortschritte Der Arzneimittelforschung. Progres Des Recherches Pharmaceutiques. 62: 83-115. PMID 16329255 DOI: 10.1007/3-7643-7426-8_3  0.339
2006 Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V. Normalized Transillumination of Fluorescent Proteins in Small Animals Molecular Imaging. 5: 7290.2006.00018. DOI: 10.2310/7290.2006.00018  0.384
2006 Sun EY, Josephson L, Weissleder R. “Clickable” Nanoparticles for Targeted Imaging Molecular Imaging. 5: 7290.2006.00013. DOI: 10.2310/7290.2006.00013  0.334
2006 Shih HA, Windsor SD, Weissleder R, Ntziachristos V. In-vivo Characterization of Her-2/neu carcinogenesis in Mice Using Fluorescence Molecular Tomography Biosilico. DOI: 10.1364/Bio.2006.Tuc1  0.341
2006 Guimaraes AR, Rakhlin EY, Long D, Weissleder R, Thayer SP. NONINVASIVE MRI IMAGING Pancreas. 33: 465-466. DOI: 10.1097/00006676-200611000-00099  0.342
2006 Tannous BA, Grimm J, Perry K, Weissleder R, Breakefield XO. Metabolic biotinylation of mammalian cell receptors for imaging Nature Protocols. DOI: 10.1038/Nprot.2006.132  0.318
2006 Tannous BA, Grimm J, Perry KF, Chen JW, Weissleder R, Breakefield XO. Erratum: Corrigendum: Metabolic biotinylation of cell surface receptors for in vivo imaging Nature Methods. 3: 657-657. DOI: 10.1038/Nmeth0806-657A  0.327
2006 Tannous BA, Perry KF, Sena-Esteves M, Garcias-Anoveros J, Jacobs A, Corey DP, Weissleder R, Breakefield XO. 959. Tumor Therapy Via Vector-Regulated Expression of Mutant Sodium Channel Molecular Therapy. 13: S370. DOI: 10.1016/J.Ymthe.2006.08.1051  0.308
2005 Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery Human Gene Therapy. 16: 1367-1376. PMID 16390268 DOI: 10.1089/Hum.2005.16.1367  0.326
2005 McCarthy JR, Perez JM, Brückner C, Weissleder R. Polymeric nanoparticle preparation that eradicates tumors. Nano Letters. 5: 2552-6. PMID 16351214 DOI: 10.1021/Nl0519229  0.436
2005 Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V. Volumetric tomography of fluorescent proteins through small animals in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 18252-7. PMID 16344470 DOI: 10.1073/Pnas.0504628102  0.406
2005 Kelloff GJ, Krohn KA, Larson SM, Weissleder R, Mankoff DA, Hoffman JM, Link JM, Guyton KZ, Eckelman WC, Scher HI, O'Shaughnessy J, Cheson BD, Sigman CC, Tatum JL, Mills GQ, et al. The progress and promise of molecular imaging probes in oncologic drug development. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7967-85. PMID 16299226 DOI: 10.1158/1078-0432.Ccr-05-1302  0.384
2005 Querol Sans M, Chen JW, Weissleder R, Bogdanov AA. Myeloperoxidase activity imaging using (67)Ga labeled substrate. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 7: 403-10. PMID 16292477 DOI: 10.1007/S11307-005-0020-5  0.322
2005 Harisinghani MG, Saksena M, Ross RW, Tabatabaei S, Dahl D, McDougal S, Weissleder R. A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation. Urology. 66: 1066-71. PMID 16286125 DOI: 10.1016/J.Urology.2005.05.049  0.307
2005 Weissleder R, Kelly K, Sun EY, Shtatland T, Josephson L. Cell-specific targeting of nanoparticles by multivalent attachment of small molecules. Nature Biotechnology. 23: 1418-23. PMID 16244656 DOI: 10.1038/Nbt1159  0.354
2005 Funovics M, Montet X, Reynolds F, Weissleder R, Josephson L. Nanoparticles for the optical imaging of tumor E-selectin. Neoplasia (New York, N.Y.). 7: 904-11. PMID 16242073 DOI: 10.1593/Neo.05352  0.366
2005 Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA. Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor. Cancer Research. 65: 9253-60. PMID 16230386 DOI: 10.1158/0008-5472.Can-03-2619  0.344
2005 Reichardt W, Hu-Lowe D, Torres D, Weissleder R, Bogdanov A. Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model. Neoplasia (New York, N.Y.). 7: 847-53. PMID 16229807 DOI: 10.1593/Neo.05139  0.357
2005 Grimm J, Kirsch DG, Windsor SD, Kim CF, Santiago PM, Ntziachristos V, Jacks T, Weissleder R. Use of gene expression profiling to direct in vivo molecular imaging of lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 102: 14404-9. PMID 16183744 DOI: 10.1073/Pnas.0503920102  0.366
2005 Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V. Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography. Journal of Biomedical Optics. 10: 44019. PMID 16178652 DOI: 10.1117/1.1993427  0.357
2005 Hilderbrand SA, Kelly KA, Weissleder R, Tung CH. Monofunctional near-infrared fluorochromes for imaging applications. Bioconjugate Chemistry. 16: 1275-81. PMID 16173808 DOI: 10.1021/Bc0501799  0.352
2005 Reynolds F, Weissleder R, Josephson L. Protamine as an efficient membrane-translocating peptide. Bioconjugate Chemistry. 16: 1240-5. PMID 16173804 DOI: 10.1021/Bc0501451  0.317
2005 Tang Y, Kim M, Carrasco D, Kung AL, Chin L, Weissleder R. In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging. Cancer Research. 65: 8324-30. PMID 16166309 DOI: 10.1158/0008-5472.Can-05-0027  0.35
2005 Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D. Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes. The Journal of Clinical Investigation. 115: 2454-61. PMID 16110329 DOI: 10.1172/Jci25048  0.306
2005 Gillies RJ, Hoffman JM, Lam KS, Menkens AE, Piwnica-Worms DR, Sullivan DC, Weissleder R. Meeting report: high-throughput technologies for in vivo imaging agents. Molecular Imaging. 4: 98-103. PMID 16105507 DOI: 10.1162/15353500200505115  0.358
2005 Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L. Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle. Magnetic Resonance in Medicine. 54: 718-24. PMID 16086367 DOI: 10.1002/Mrm.20617  0.382
2005 Choi HK, Yessayan D, Choi HJ, Schellenberger E, Bogdanov A, Josephson L, Weissleder R, Ntziachristos V. Quantitative analysis of chemotherapeutic effects in tumors using in vivo staining and correlative histology. Cellular Oncology : the Official Journal of the International Society For Cellular Oncology. 27: 183-90. PMID 16037639 DOI: 10.1155/2005/791936  0.318
2005 Montet X, Ntziachristos V, Grimm J, Weissleder R. Tomographic fluorescence mapping of tumor targets. Cancer Research. 65: 6330-6. PMID 16024635 DOI: 10.1158/0008-5472.Can-05-0382  0.395
2005 Zacharakis G, Ripoll J, Weissleder R, Ntziachristos V. Fluorescent protein tomography scanner for small animal imaging. Ieee Transactions On Medical Imaging. 24: 878-85. PMID 16011317 DOI: 10.1109/Tmi.2004.843254  0.373
2005 Law B, Weissleder R, Tung CH. Mechanism-based fluorescent reporter for protein kinase A detection. Chembiochem : a European Journal of Chemical Biology. 6: 1361-7. PMID 16010698 DOI: 10.1002/Cbic.200500027  0.302
2005 Shah K, Tung CH, Breakefield XO, Weissleder R. In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 926-31. PMID 15922963 DOI: 10.1016/J.Ymthe.2005.01.017  0.356
2005 Bremer C, Ntziachristos V, Weitkamp B, Theilmeier G, Heindel W, Weissleder R. Optical imaging of spontaneous breast tumors using protease sensing 'smart' optical probes Investigative Radiology. 40: 321-327. PMID 15905717 DOI: 10.1097/01.Rli.0000163797.23172.90  0.323
2005 Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U. A novel mouse model for segmental orthotopic colon cancer International Journal of Cancer. 117: 335-339. PMID 15900588 DOI: 10.1002/Ijc.21185  0.326
2005 Tsourkas A, Shinde-Patil VR, Kelly KA, Patel P, Wolley A, Allport JR, Weissleder R. In vivo imaging of activated endothelium using an anti-VCAM-1 magnetooptical probe. Bioconjugate Chemistry. 16: 576-81. PMID 15898724 DOI: 10.1021/Bc050002E  0.378
2005 Shah K, Weissleder R. Molecular optical imaging: applications leading to the development of present day therapeutics. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 2: 215-25. PMID 15897946 DOI: 10.1602/Neurorx.2.2.215  0.406
2005 Tsourkas A, Newton G, Perez JM, Basilion JP, Weissleder R. Detection of peroxidase/H2O2-mediated oxidation with enhanced yellow fluorescent protein. Analytical Chemistry. 77: 2862-7. PMID 15859603 DOI: 10.1021/Ac0480747  0.413
2005 Querol M, Chen JW, Weissleder R, Bogdanov A. DTPA-bisamide-based MR sensor agents for peroxidase imaging. Organic Letters. 7: 1719-22. PMID 15844889 DOI: 10.1021/Ol050208V  0.327
2005 Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL. Near-infrared fluorescent imaging of matrix metalloproteinase activity after myocardial infarction. Circulation. 111: 1800-5. PMID 15809374 DOI: 10.1161/01.Cir.0000160936.91849.9F  0.301
2005 Tung CH, Quinti L, Jaffer FA, Weissleder R. A branched fluorescent peptide probe for imaging of activated platelets. Molecular Pharmaceutics. 2: 92-5. PMID 15804182 DOI: 10.1021/Mp0499048  0.33
2005 Ntziachristos V, Ripoll J, Wang LV, Weissleder R. Looking and listening to light: the evolution of whole-body photonic imaging. Nature Biotechnology. 23: 313-20. PMID 15765087 DOI: 10.1038/Nbt1074  0.359
2005 Chen WT, Mahmood U, Weissleder R, Tung CH. Arthritis imaging using a near-infrared fluorescence folate-targeted probe. Arthritis Research & Therapy. 7: R310-7. PMID 15743478 DOI: 10.1186/Ar1483  0.368
2005 Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO. Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 435-43. PMID 15727940 DOI: 10.1016/J.Ymthe.2004.10.016  0.355
2005 Jaffer FA, Weissleder R. Molecular imaging in the clinical arena. Jama. 293: 855-62. PMID 15713776 DOI: 10.1001/Jama.293.7.855  0.37
2005 Law B, Hsiao JK, Bugge TH, Weissleder R, Tung CH. Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples. Analytical Biochemistry. 338: 151-8. PMID 15707946 DOI: 10.1016/J.Ab.2004.11.039  0.329
2005 Kim DE, Schellingerhout D, Jaffer FA, Weissleder R, Tung CH. Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 25: 226-33. PMID 15678125 DOI: 10.1038/Sj.Jcbfm.9600023  0.347
2005 Kelly KA, Allport JR, Tsourkas A, Shinde-Patil VR, Josephson L, Weissleder R. Detection of vascular adhesion molecule-1 expression using a novel multimodal nanoparticle. Circulation Research. 96: 327-36. PMID 15653572 DOI: 10.1161/01.Res.0000155722.17881.Dd  0.373
2005 Shah K, Bureau E, Kim DE, Yang K, Tang Y, Weissleder R, Breakefield XO. Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression. Annals of Neurology. 57: 34-41. PMID 15622535 DOI: 10.1002/Ana.20306  0.348
2005 Pham W, Choi Y, Weissleder R, Tung CH. Developing a peptide-based near-infrared molecular probe for protease sensing. Bioconjugate Chemistry. 15: 1403-7. PMID 15546208 DOI: 10.1021/Bc049924S  0.322
2005 Chen WT, Tung CH, Weissleder R. Imaging reactive oxygen species in arthritis. Molecular Imaging. 3: 159-62. PMID 15530251 DOI: 10.1162/1535350042380290  0.324
2005 Schellenberger EA, Sosnovik D, Weissleder R, Josephson L. Magneto/optical annexin V, a multimodal protein. Bioconjugate Chemistry. 15: 1062-7. PMID 15366960 DOI: 10.1021/Bc049905I  0.345
2005 Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R. MIPortal: A High Capacity Server for Molecular Imaging Research Molecular Imaging. 4: 7290.2005.05136. DOI: 10.2310/7290.2005.05136  0.325
2005 Montet-Abou K, Montet X, Weissleder R, Josephson L. Transfection Agent Induced Nanoparticle Cell Loading Molecular Imaging. 4: 153535002005051. DOI: 10.1162/15353500200505100  0.342
2005 Chen W, Khazaie K, Zhang G, Weissleder R, Tung C. Detection of Dysplastic Intestinal Adenomas Using a Fluorescent Folate Imaging Probe Molecular Imaging. 4: 153535002005041. DOI: 10.1162/15353500200504199  0.404
2005 Wunder A, Schellenberger E, Mahmood U, Bogdanov A, Müller-Ladner U, Weissleder R, Josephson L. Methotrexate-Induced Accumulation of Fluorescent Annexin V in Collagen-Induced Arthritis Molecular Imaging. 4: 153535002005041. DOI: 10.1162/15353500200504142  0.336
2005 Zhu B, Jaffer FA, Ntziachristos V, Weissleder R. Development of a near infrared fluorescence catheter: operating characteristics and feasibility for atherosclerotic plaque detection Journal of Physics D: Applied Physics. 38: 2701-2707. DOI: 10.1088/0022-3727/38/15/024  0.354
2005 Fulci G, Breymann LM, Fontana EJ, Gianni D, Wakimoto H, Weissleder R, Lee R, Liu Q, Chiocca AE. 283. Suppression of Inflammatory Pathways Selectively Induced by Oncolytic Viruses Enhances Viral Oncolysis Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.286  0.313
2005 Funovics MA, Su HS, Weissleder R, Mahmood U. Fiberoptic catheter-based near infrared imaging of protease activity and marker gene expression Academic Radiology. 12: S76-S77. DOI: 10.1016/J.Acra.2005.03.040  0.315
2005 Mahmood U, Wunder A, Weissleder R. Optical imaging of protease activity in rheumatoid arthritis Academic Radiology. 12: S75-S76. DOI: 10.1016/J.Acra.2005.03.039  0.336
2004 Harisinghani MG, Weissleder R. Sensitive, noninvasive detection of lymph node metastases. Plos Medicine. 1: e66. PMID 15630471 DOI: 10.1371/Journal.Pmed.0010066  0.304
2004 Chen JW, Pham W, Weissleder R, Bogdanov A. Human myeloperoxidase: a potential target for molecular MR imaging in atherosclerosis. Magnetic Resonance in Medicine. 52: 1021-8. PMID 15508166 DOI: 10.1002/Mrm.20270  0.366
2004 Graves EE, Weissleder R, Ntziachristos V. Fluorescence molecular imaging of small animal tumor models. Current Molecular Medicine. 4: 419-30. PMID 15354872 DOI: 10.2174/1566524043360555  0.402
2004 Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R. Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Research. 64: 6247-51. PMID 15342411 DOI: 10.1158/0008-5472.Can-04-0817  0.349
2004 Kim YR, Savellano MD, Savellano DH, Weissleder R, Bogdanov A. Measurement of tumor interstitial volume fraction: method and implication for drug delivery. Magnetic Resonance in Medicine. 52: 485-94. PMID 15334566 DOI: 10.1002/Mrm.20182  0.321
2004 Ntziachristos V, Schellenberger EA, Ripoll J, Yessayan D, Graves E, Bogdanov A, Josephson L, Weissleder R. Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proceedings of the National Academy of Sciences of the United States of America. 101: 12294-9. PMID 15304657 DOI: 10.1073/Pnas.0401137101  0.414
2004 Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R. Molecular imaging of factor XIIIa activity in thrombosis using a novel, near-infrared fluorescent contrast agent that covalently links to thrombi. Circulation. 110: 170-6. PMID 15210587 DOI: 10.1161/01.Cir.0000134484.11052.44  0.34
2004 Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS. Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Research. 64: 4069-77. PMID 15205313 DOI: 10.1158/0008-5472.Can-04-1243  0.3
2004 Funovics MA, Weissleder R, Mahmood U. Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 231: 659-66. PMID 15163807 DOI: 10.1148/Radiol.2313030831  0.349
2004 Shah K, Jacobs A, Breakefield XO, Weissleder R. Molecular imaging of gene therapy for cancer. Gene Therapy. 11: 1175-87. PMID 15141158 DOI: 10.1038/Sj.Gt.3302278  0.405
2004 Shah K, Tung CH, Yang K, Weissleder R, Breakefield XO. Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy. Cancer Research. 64: 3236-42. PMID 15126365 DOI: 10.1158/0008-5472.Can-03-3516  0.328
2004 Law B, Curino A, Bugge TH, Weissleder R, Tung CH. Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter. Chemistry & Biology. 11: 99-106. PMID 15112999 DOI: 10.1016/J.Chembiol.2003.12.017  0.362
2004 Kircher MF, Weissleder R, Josephson L. A dual fluorochrome probe for imaging proteases. Bioconjugate Chemistry. 15: 242-8. PMID 15025519 DOI: 10.1021/Bc034151D  0.355
2004 Jaffer FA, Weissleder R. Seeing within: molecular imaging of the cardiovascular system. Circulation Research. 94: 433-45. PMID 15001542 DOI: 10.1161/01.Res.0000119321.18573.5A  0.385
2004 Schellenberger EA, Reynolds F, Weissleder R, Josephson L. Surface-functionalized nanoparticle library yields probes for apoptotic cells. Chembiochem : a European Journal of Chemical Biology. 5: 275-9. PMID 14997519 DOI: 10.1002/Cbic.200300713  0.34
2004 Perez JM, Josephson L, Weissleder R. Use of magnetic nanoparticles as nanosensors to probe for molecular interactions. Chembiochem : a European Journal of Chemical Biology. 5: 261-4. PMID 14997516 DOI: 10.1002/Cbic.200300730  0.37
2004 Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout D, Weissleder R. In vivo imaging of beta-galactosidase activity using far red fluorescent switch. Cancer Research. 64: 1579-83. PMID 14996712 DOI: 10.1158/0008-5472.Can-03-3226  0.328
2004 Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R. Imaging of stem cell recruitment to ischemic infarcts in a murine model. Stroke. 35: 952-7. PMID 14988578 DOI: 10.1161/01.Str.0000120308.21946.5D  0.334
2004 Graves EE, Culver JP, Ripoll J, Weissleder R, Ntziachristos V. Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography. Journal of the Optical Society of America. a, Optics, Image Science, and Vision. 21: 231-41. PMID 14763766 DOI: 10.1364/Josaa.21.000231  0.321
2004 Grimm J, Perez JM, Josephson L, Weissleder R. Novel nanosensors for rapid analysis of telomerase activity. Cancer Research. 64: 639-43. PMID 14744779 DOI: 10.1158/0008-5472.Can-03-2798  0.414
2004 Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R. In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas. Cancer Research. 64: 273-8. PMID 14729634 DOI: 10.1158/0008-5472.Can-03-1123  0.335
2004 Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R. In vivo tracking of neural progenitor cell migration to glioblastomas. Human Gene Therapy. 14: 1247-54. PMID 12952596 DOI: 10.1089/104303403767740786  0.326
2004 Perez JM, Simeone FJ, Saeki Y, Josephson L, Weissleder R. Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media. Journal of the American Chemical Society. 125: 10192-3. PMID 12926940 DOI: 10.1021/Ja036409G  0.38
2004 Allport JR, Weissleder R. Murine Lewis lung carcinoma-derived endothelium expresses markers of endothelial activation and requires tumor-specific extracellular matrix in vitro. Neoplasia (New York, N.Y.). 5: 205-17. PMID 12869304 DOI: 10.1016/S1476-5586(03)80053-2  0.319
2004 Moon WK, Lin Y, O'Loughlin T, Tang Y, Kim DE, Weissleder R, Tung CH. Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate. Bioconjugate Chemistry. 14: 539-45. PMID 12757377 DOI: 10.1021/Bc0340114  0.41
2004 Kang HW, Weissleder R, Bogdanov A. Targeting of MPEG-protected polyamino acid carrier to human E-selectin in vitro. Amino Acids. 23: 301-8. PMID 12373551 DOI: 10.1007/S00726-001-0142-2  0.344
2004 Zacharakis G, Ripoll J, Ishii K, Kambara H, Saeki Y, Weissleder R, Ntziachristos V. Three-dimensional optical tomography of fluorescent proteins in the visible Biosilico. DOI: 10.1364/Bio.2004.Sa3  0.313
2004 Vianello F, Papeta N, Kircher MF, Toner M, Weissleder R, Irimia D, Poznansky MC. Murine Melanomas Expressing High Levels of SDF-1 Repel and Escape Control by Tumor Specific T-Cells. Blood. 104: 445-445. DOI: 10.1182/Blood.V104.11.445.445  0.33
2004 Ross B, Rehemtulla A, Koo YEL, Reddy R, Kim G, Behrend C, Buck S, Schneider RJ, Philbert MA, Weissleder R, Kopelman R. Photonic and magnetic nanoexplorers for biomedical use: From subcellular imaging to cancer diagnostics and therapy Proceedings of Spie - the International Society For Optical Engineering. 5331: 76-83. DOI: 10.1117/12.537653  0.369
2004 Perez JM, Simeone FJ, Tsourkas A, Josephson L, Weissleder R. Peroxidase Substrate Nanosensors for MR Imaging Nano Letters. 4: 119-122. DOI: 10.1021/Nl034983K  0.317
2003 Högemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP. The transferrin receptor: a potential molecular imaging marker for human cancer. Neoplasia (New York, N.Y.). 5: 495-506. PMID 14965443 DOI: 10.1016/S1476-5586(03)80034-9  0.431
2003 Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U. Miniaturized multichannel near infrared endoscope for mouse imaging. Molecular Imaging. 2: 350-7. PMID 14717334 DOI: 10.1162/153535003322750691  0.352
2003 Moffat BA, Reddy GR, McConville P, Hall DE, Chenevert TL, Kopelman RR, Philbert M, Weissleder R, Rehemtulla A, Ross BD. A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI. Molecular Imaging. 2: 324-32. PMID 14717331 DOI: 10.1162/153535003322750664  0.326
2003 Koch AM, Reynolds F, Kircher MF, Merkle HP, Weissleder R, Josephson L. Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells. Bioconjugate Chemistry. 14: 1115-21. PMID 14624624 DOI: 10.1021/Bc034123V  0.32
2003 Shah K, Tang Y, Breakefield X, Weissleder R. Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo. Oncogene. 22: 6865-72. PMID 14534533 DOI: 10.1038/Sj.Onc.1206748  0.347
2003 Pham W, Lai WF, Weissleder R, Tung CH. High efficiency synthesis of a bioconjugatable near-infrared fluorochrome. Bioconjugate Chemistry. 14: 1048-51. PMID 13129411 DOI: 10.1021/Bc034070H  0.302
2003 Lin Y, Weissleder R, Tung CH. Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging. Molecular Imaging. 2: 87-92. PMID 12964306 DOI: 10.1162/153535003322331975  0.334
2003 Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R. Novel factor XIII probes for blood coagulation imaging. Chembiochem : a European Journal of Chemical Biology. 4: 897-9. PMID 12964167 DOI: 10.1002/Cbic.200300602  0.326
2003 Funovics M, Weissleder R, Tung CH. Protease sensors for bioimaging. Analytical and Bioanalytical Chemistry. 377: 956-63. PMID 12955390 DOI: 10.1007/S00216-003-2199-0  0.397
2003 Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, et al. Neural stem cell biology may be well suited for improving brain tumor therapies. Cancer Journal (Sudbury, Mass.). 9: 189-204. PMID 12952304 DOI: 10.1097/00130404-200305000-00007  0.326
2003 Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R. Coded aperture nuclear scintigraphy: a novel small animal imaging technique. Molecular Imaging. 1: 344-53. PMID 12926230 DOI: 10.1162/153535002321093954  0.344
2003 Schellenberger EA, Bogdanov A, Petrovsky A, Ntziachristos V, Weissleder R, Josephson L. Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy. Neoplasia (New York, N.Y.). 5: 187-92. PMID 12869301 DOI: 10.1016/S1476-5586(03)80050-7  0.352
2003 Graves EE, Ripoll J, Weissleder R, Ntziachristos V. A submillimeter resolution fluorescence molecular imaging system for small animal imaging. Medical Physics. 30: 901-11. PMID 12772999 DOI: 10.1118/1.1568977  0.384
2003 Bremer C, Ntziachristos V, Weissleder R. Optical-based molecular imaging: Contrast agents and potential medical applications European Radiology. 13: 231-243. PMID 12598985 DOI: 10.1007/S00330-002-1610-0  0.344
2003 Rudin M, Weissleder R. Molecular imaging in drug discovery and development. Nature Reviews. Drug Discovery. 2: 123-31. PMID 12563303 DOI: 10.1038/Nrd1007  0.371
2003 Ntziachristos V, Bremer C, Weissleder R. Fluorescence imaging with near-infrared light: New technological advances that enable in vivo molecular imaging European Radiology. 13: 195-208. PMID 12541130 DOI: 10.1007/S00330-002-1524-X  0.396
2003 Weissleder R, Ntziachristos V. Shedding light onto live molecular targets. Nature Medicine. 9: 123-8. PMID 12514725 DOI: 10.1038/Nm0103-123  0.33
2003 Bremer C, Mustafa M, Bogdanov A, Ntziachristos V, Petrovsky A, Weissleder R. Steady-state blood volume measurements in experimental tumors with different angiogenic burdens - A study in mice Radiology. 226: 214-220. PMID 12511693 DOI: 10.1148/Radiol.2261012140  0.347
2003 Tung CH, Lin Y, Moon WK, Weissleder R. A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging. Chembiochem : a European Journal of Chemical Biology. 3: 784-6. PMID 12203978 DOI: 10.1002/1439-7633(20020802)3:8<784::Aid-Cbic784>3.0.Co;2-X  0.383
2003 Schellenberger EA, Högemann D, Josephson L, Weissleder R. Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI. Academic Radiology. S310-1. PMID 12188257 DOI: 10.1016/S1076-6332(03)80212-X  0.352
2003 Zhou L, Blessington D, Zhang Z, Lindenmayer AE, Tung C, Weissleder R, Chance B. NIR imaging the delivery of cathepsin B probe to breast tumors Proceedings of Spie - the International Society For Optical Engineering. 4955: 505-512. DOI: 10.1117/12.478188  0.376
2002 Bogdanov A, Matuszewski L, Bremer C, Petrovsky A, Weissleder R. Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets. Molecular Imaging. 1: 16-23. PMID 12920857 DOI: 10.1162/153535002753395671  0.371
2002 Schellenberger EA, Bogdanov A, Högemann D, Tait J, Weissleder R, Josephson L. Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI. Molecular Imaging. 1: 102-7. PMID 12920851 DOI: 10.1162/153535002320162769  0.345
2002 Kircher MF, Josephson L, Weissleder R. Ratio imaging of enzyme activity using dual wavelength optical reporters. Molecular Imaging. 1: 89-95. PMID 12920849 DOI: 10.1162/153535002320162741  0.382
2002 Ntziachristos V, Bremer C, Graves EE, Ripoll J, Weissleder R. In vivo tomographic imaging of near-infrared fluorescent probes. Molecular Imaging. 1: 82-8. PMID 12920848 DOI: 10.1162/153535002320162732  0.389
2002 Kim YR, Savellano MD, Weissleder R, Bogdanov A. Steady-state and dynamic contrast MR imaging of human prostate cancer xenograft tumors: a comparative study. Technology in Cancer Research & Treatment. 1: 489-95. PMID 12625776 DOI: 10.1177/153303460200100609  0.347
2002 Jaffer FA, Tung CH, Gerszten RE, Weissleder R. In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1929-35. PMID 12426227 DOI: 10.1161/01.Atv.0000033089.56970.2D  0.366
2002 Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO. Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2. Neoplasia (New York, N.Y.). 4: 501-9. PMID 12407444 DOI: 10.1038/Sj.Neo.7900265  0.345
2002 Ntziachristos V, Bremer C, Tung C, Weissleder R. Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence- mediated molecular tomography (FMT) Academic Radiology. 9. PMID 12188262 DOI: 10.1016/S1076-6332(03)80217-9  0.404
2002 Bremer C, Tung CH, Weissleder R. Molecular imaging of MMP expression and therapeutic MMP inhibition Academic Radiology. 9. PMID 12188259 DOI: 10.1016/S1076-6332(03)80214-3  0.308
2002 Mahmood U, Tung CH, Tang Y, Weissleder R. Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice. Radiology. 224: 446-51. PMID 12147841 DOI: 10.1148/Radiol.2242011589  0.328
2002 Perez JM, Josephson L, O'Loughlin T, Högemann D, Weissleder R. Magnetic relaxation switches capable of sensing molecular interactions. Nature Biotechnology. 20: 816-20. PMID 12134166 DOI: 10.1038/Nbt720  0.391
2002 Zhao M, Kircher MF, Josephson L, Weissleder R. Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake. Bioconjugate Chemistry. 13: 840-4. PMID 12121140 DOI: 10.1021/Bc0255236  0.319
2002 Ntziachristos V, Tung CH, Bremer C, Weissleder R. Fluorescence molecular tomography resolves protease activity in vivo Nature Medicine. 8: 757-760. PMID 12091907 DOI: 10.1038/Nm729  0.381
2002 Mahmood U, Weissleder R. Some tools for molecular imaging. Academic Radiology. 9: 629-31. PMID 12061735 DOI: 10.1016/S1076-6332(03)80306-9  0.368
2002 Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R. In vivo imaging of proteolytic activity in atherosclerosis. Circulation. 105: 2766-71. PMID 12057992 DOI: 10.1161/01.Cir.0000017860.20619.23  0.334
2002 Ntziachristos V, Weissleder R. Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media. Medical Physics. 29: 803-9. PMID 12033576 DOI: 10.1118/1.1470209  0.315
2002 Lin Y, Weissleder R, Tung CH. Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation. Bioconjugate Chemistry. 13: 605-10. PMID 12009952 DOI: 10.1021/Bc0155723  0.339
2002 Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R. Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes. Bioconjugate Chemistry. 13: 554-60. PMID 12009946 DOI: 10.1021/Bc015555D  0.395
2002 Bogdanov AA, Lin CP, Simonova M, Matuszewski L, Weissleder R. Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment. Neoplasia (New York, N.Y.). 4: 228-36. PMID 11988842 DOI: 10.1038/Sj.Neo.7900238  0.384
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