Year |
Citation |
Score |
2023 |
Savadipour A, Nims RJ, Rashidi N, Garcia-Castorena JM, Tang R, Marushack GK, Oswald SJ, Liedtke WB, Guilak F. Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221958120. PMID 37459546 DOI: 10.1073/pnas.2221958120 |
0.529 |
|
2023 |
Dicks AR, Maksaev GI, Harissa Z, Savadipour A, Tang R, Steward N, Liedtke W, Nichols CG, Wu CL, Guilak F. Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes. Elife. 12. PMID 36810131 DOI: 10.7554/eLife.71154 |
0.462 |
|
2023 |
Benítez-Angeles M, Romero AEL, Llorente I, Hernández-Araiza I, Vergara-Jaque A, Real FH, Castañeda ÓEG, Arciniega M, Morales-Buenrostro LE, Torres-Quiroz F, García-Villegas R, Tovar-Y-Romo LB, Liedtke WB, Islas LD, Rosenbaum T. Modes of action of lysophospholipids as endogenous activators of the TRPV4 ion channel. The Journal of Physiology. PMID 36625071 DOI: 10.1113/JP284262 |
0.312 |
|
2021 |
Willard VP, Leddy HA, Palmer D, Wu CL, Liedtke W, Guilak F. Transient receptor potential vanilloid 4 as a regulator of induced pluripotent stem cell chondrogenesis. Stem Cells (Dayton, Ohio). PMID 34427363 DOI: 10.1002/stem.3440 |
0.522 |
|
2021 |
Lee W, Nims RJ, Savadipour A, Zhang Q, Leddy HA, Liu F, McNulty AL, Chen Y, Guilak F, Liedtke WB. Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33758095 DOI: 10.1073/pnas.2001611118 |
0.77 |
|
2021 |
Nims RJ, Pferdehirt L, Ho NB, Savadipour A, Lorentz J, Sohi S, Kassab J, Ross AK, O'Conor CJ, Liedtke WB, Zhang B, McNulty AL, Guilak F. A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues. Science Advances. 7. PMID 33571125 DOI: 10.1126/sciadv.abd9858 |
0.47 |
|
2020 |
Rosenkranz SC, Shaposhnykov A, Schnapauff O, Epping L, Vieira V, Heidermann K, Schattling B, Tsvilovskyy V, Liedtke W, Meuth SG, Freichel M, Gelderblom M, Friese MA. TRPV4-Mediated Regulation of the Blood Brain Barrier Is Abolished During Inflammation. Frontiers in Cell and Developmental Biology. 8: 849. PMID 32974355 DOI: 10.3389/Fcell.2020.00849 |
0.361 |
|
2020 |
Kuebler W, Jordt SE, Liedtke W. COVID-19: Urgent Reconsideration of Lung Edema as a Preventable Outcome: Inhibition of TRPV4 As a Promising and Feasible Approach. Ssrn. 3558887. PMID 32714108 DOI: 10.2139/ssrn.3558887 |
0.605 |
|
2020 |
Naik SK, Pattanaik K, Eich J, Sparr V, Hauptmann M, Kalsdorf B, Reiling N, Liedtke W, Kuebler WM, Schaible UE, Sonawane A. Differential Roles of the Calcium Ion Channel TRPV4 in Host Responses to Mycobacterium tuberculosis Early and Late in Infection. Iscience. 23: 101206. PMID 32535021 DOI: 10.1016/J.Isci.2020.101206 |
0.315 |
|
2020 |
Kuebler WM, Jordt SE, Liedtke WB. Urgent reconsideration of lung edema as a preventable outcome in COVID-19: Inhibition of TRPV4 represents a promising and feasible approach. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 32401673 DOI: 10.1152/Ajplung.00161.2020 |
0.605 |
|
2020 |
Ottolini M, Hong K, Cope EL, Daneva Z, DeLalio LJ, Sokolowski JD, Marziano C, Nguyen NY, Altschmied J, Haendeler J, Johnstone SR, Kalani MY, Park MS, Patel RP, Liedtke W, et al. Local Peroxynitrite Impairs Endothelial TRPV4 Channels and Elevates Blood Pressure in Obesity. Circulation. PMID 32008372 DOI: 10.1161/Circulationaha.119.043385 |
0.342 |
|
2020 |
Swain SM, Romac JM, Shahid RA, Pandol SJ, Liedtke W, Vigna SR, Liddle RA. TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation. The Journal of Clinical Investigation. PMID 31999644 DOI: 10.1172/Jci134111 |
0.346 |
|
2019 |
Gilchrist CL, Leddy HA, Kaye L, Case ND, Rothenberg KE, Little D, Liedtke W, Hoffman BD, Guilak F. TRPV4-mediated calcium signaling in mesenchymal stem cells regulates aligned collagen matrix formation and vinculin tension. Proceedings of the National Academy of Sciences of the United States of America. PMID 30674675 DOI: 10.1073/Pnas.1811095116 |
0.558 |
|
2018 |
Ciura S, Prager-Khoutorsky M, Thirouin ZS, Wyrosdic JC, Olson JE, Liedtke W, Bourque CW. Trpv4 Mediates Hypotonic Inhibition of Central Osmosensory Neurons via Taurine Gliotransmission. Cell Reports. 23: 2245-2253. PMID 29791836 DOI: 10.1016/J.Celrep.2018.04.090 |
0.462 |
|
2017 |
Moore C, Gupta R, Jordt SE, Chen Y, Liedtke WB. Regulation of Pain and Itch by TRP Channels. Neuroscience Bulletin. PMID 29282613 DOI: 10.1007/S12264-017-0200-8 |
0.661 |
|
2017 |
Rodriguez E, Sakurai K, Xu J, Chen Y, Toda K, Zhao S, Han BX, Ryu D, Yin H, Liedtke W, Wang F. A craniofacial-specific monosynaptic circuit enables heightened affective pain. Nature Neuroscience. 20: 1734-1743. PMID 29184209 DOI: 10.1038/S41593-017-0012-1 |
0.316 |
|
2017 |
Lee W, Guilak F, Liedtke W. Role of Piezo Channels in Joint Health and Injury. Current Topics in Membranes. 79: 263-273. PMID 28728820 DOI: 10.1016/Bs.Ctm.2016.10.003 |
0.78 |
|
2017 |
Benemei S, De Logu F, Li Puma S, Marone IM, Coppi E, Ugolini F, Liedtke W, Pollastro F, Appendino G, Geppetti P, Materazzi S, Nassini R. The anti-migraine component of butterbur extracts, isopetasin, desensitizes peptidergic nociceptors by acting on TRPA1 cation channel. British Journal of Pharmacology. 174: 2897-2911. PMID 28622417 DOI: 10.1111/Bph.13917 |
0.355 |
|
2017 |
Chen Y, Moore CD, Zhang JY, Hall RP, MacLeod AS, Liedtke W. TRPV4 Moves toward Center-Fold in Rosacea Pathogenesis. The Journal of Investigative Dermatology. 137: 801-804. PMID 28340683 DOI: 10.1016/J.Jid.2016.12.013 |
0.385 |
|
2017 |
Michalick L, Erfinanda L, Weichelt U, van der Giet M, Liedtke W, Kuebler WM. Transient Receptor Potential Vanilloid 4 and Serum Glucocorticoid-regulated Kinase 1 Are Critical Mediators of Lung Injury in Overventilated Mice In Vivo. Anesthesiology. 126: 300-311. PMID 27861175 DOI: 10.1097/Aln.0000000000001443 |
0.371 |
|
2017 |
Erfinanda L, Lin Z, Gutbier B, Reppe K, Lienau J, Hocke A, Liedtke W, Witzenrath M, Kuebler WM. Loss of CFTR causes endothelial barrier failure in pneumonia via inhibition of WNK1 and TRPV4 activation European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Pa1874 |
0.355 |
|
2016 |
Seth RK, Das S, Dattaroy D, Chandrashekaran V, Alhasson F, Michelotti G, Nagarkatti M, Nagarkatti P, Diehl AM, Bell DP, Liedtke W, Chatterjee S. TRPV4 activation of endothelial nitric oxide synthase resists nonalcoholic fatty liver disease by blocking CYP2E1-mediated redox toxicity. Free Radical Biology & Medicine. PMID 27913210 DOI: 10.1016/J.Freeradbiomed.2016.11.047 |
0.34 |
|
2016 |
Kanju P, Liedtke W. Pleiotropic function of TRPV4 ion channels in the central nervous system. Experimental Physiology. 101: 1472-1476. PMID 27701788 DOI: 10.1113/Ep085790 |
0.438 |
|
2016 |
O'Conor CJ, Ramalingam S, Zelenski NA, Benefield HC, Rigo I, Little D, Wu CL, Chen D, Liedtke W, McNulty AL, Guilak F. Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis. Scientific Reports. 6: 29053. PMID 27388701 DOI: 10.1038/Srep29053 |
0.588 |
|
2016 |
Kanju P, Chen Y, Lee W, Yeo M, Lee SH, Romac J, Shahid R, Fan P, Gooden DM, Simon SA, Spasojevic I, Mook RA, Liddle RA, Guilak F, Liedtke WB. Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain. Scientific Reports. 6: 26894. PMID 27247148 DOI: 10.1038/Srep26894 |
0.762 |
|
2016 |
Chen Y, Fang Q, Wang Z, Zhang JY, MacLeod AS, Hall RP, Liedtke WB. Transient receptor potential vanilloid 4 ion channel functions as a pruriceptor in epidermal keratinocytes to evoke histaminergic itch. The Journal of Biological Chemistry. PMID 26961876 DOI: 10.1074/jbc.M116.716464 |
0.338 |
|
2016 |
Lee W, Leddy H, McNulty A, Guilak F, Liedtke W. Inflammatory Cytokine Il-1α Up-Regulates Piezo1 and Hyper-Sensitizes Chondrocytes to Compression Biophysical Journal. 110: 349a. DOI: 10.1016/J.Bpj.2015.11.1878 |
0.768 |
|
2015 |
Rajasekhar P, Poole DP, Liedtke W, Bunnett NW, Veldhuis NA. P2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells. The Journal of Biological Chemistry. 290: 29051-62. PMID 26475857 DOI: 10.1074/Jbc.M115.689729 |
0.454 |
|
2015 |
Zaelzer C, Hua P, Prager-Khoutorsky M, Ciura S, Voisin DL, Liedtke W, Bourque CW. ΔN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress. Cell Reports. 13: 23-30. PMID 26387947 DOI: 10.1016/J.Celrep.2015.08.061 |
0.409 |
|
2015 |
Lin MT, Jian MY, Taylor MS, Cioffi DL, Yap FC, Liedtke W, Townsley MI. Functional coupling of TRPV4, IK, and SK channels contributes to Ca(2+)-dependent endothelial injury in rodent lung. Pulmonary Circulation. 5: 279-90. PMID 26064452 DOI: 10.1086/680166 |
0.436 |
|
2015 |
Cenac N, Bautzova T, Le Faouder P, Veldhuis NA, Poole DP, Rolland C, Bertrand J, Liedtke W, Dubourdeau M, Bertrand-Michel J, Zecchi L, Stanghellini V, Bunnett NW, Barbara G, Vergnolle N. Quantification and Potential Functions of Endogenous Agonists of Transient Receptor Potential Channels in Patients With Irritable Bowel Syndrome. Gastroenterology. 149: 433-44.e7. PMID 25911511 DOI: 10.1053/J.Gastro.2015.04.011 |
0.382 |
|
2015 |
Zhang Y, Chen Y, Liedtke W, Wang F. Lack of evidence for ectopic sprouting of genetically labeled Aβ touch afferents in inflammatory and neuropathic trigeminal pain. Molecular Pain. 11: 18. PMID 25880319 DOI: 10.1186/S12990-015-0017-2 |
0.311 |
|
2015 |
Zhao P, Lieu T, Barlow N, Sostegni S, Haerteis S, Korbmacher C, Liedtke W, Jimenez-Vargas NN, Vanner SJ, Bunnett NW. Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain. The Journal of Biological Chemistry. 290: 13875-87. PMID 25878251 DOI: 10.1074/Jbc.M115.642736 |
0.416 |
|
2015 |
Zelenski NA, Leddy HA, Sanchez-Adams J, Zhang J, Bonaldo P, Liedtke W, Guilak F. Type VI Collagen Regulates Pericellular Matrix Properties, Chondrocyte Swelling, and Mechanotransduction in Mouse Articular Cartilage. Arthritis & Rheumatology (Hoboken, N.J.). 67: 1286-94. PMID 25604429 DOI: 10.1002/Art.39034 |
0.573 |
|
2015 |
McNulty AL, Leddy HA, Liedtke W, Guilak F. TRPV4 as a therapeutic target for joint diseases. Naunyn-Schmiedeberg's Archives of Pharmacology. 388: 437-50. PMID 25519495 DOI: 10.1007/S00210-014-1078-X |
0.59 |
|
2014 |
Leddy HA, McNulty AL, Guilak F, Liedtke W. Unraveling the mechanism by which TRPV4 mutations cause skeletal dysplasias. Rare Diseases (Austin, Tex.). 2: e962971. PMID 26942100 DOI: 10.4161/2167549X.2014.962971 |
0.481 |
|
2014 |
Liedtke W. A precisely defined role for the tip link-associated protein TMIE in the mechanoelectrical transduction channel complex of inner ear hair cells. Neuron. 84: 889-91. PMID 25475183 DOI: 10.1016/J.Neuron.2014.11.015 |
0.3 |
|
2014 |
Lee W, Leddy HA, Chen Y, Lee SH, Zelenski NA, McNulty AL, Wu J, Beicker KN, Coles J, Zauscher S, Grandl J, Sachs F, Guilak F, Liedtke WB. Synergy between Piezo1 and Piezo2 channels confers high-strain mechanosensitivity to articular cartilage. Proceedings of the National Academy of Sciences of the United States of America. 111: E5114-22. PMID 25385580 DOI: 10.1073/Pnas.1414298111 |
0.772 |
|
2014 |
Chen Y, Kanju P, Fang Q, Lee SH, Parekh PK, Lee W, Moore C, Brenner D, Gereau RW, Wang F, Liedtke W. TRPV4 is necessary for trigeminal irritant pain and functions as a cellular formalin receptor. Pain. 155: 2662-72. PMID 25281928 DOI: 10.1016/J.Pain.2014.09.033 |
0.746 |
|
2014 |
Lindy AS, Parekh PK, Zhu R, Kanju P, Chintapalli SV, Tsvilovskyy V, Patterson RL, Anishkin A, van Rossum DB, Liedtke WB. TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour. Nature Communications. 5: 4734. PMID 25178952 DOI: 10.1038/Ncomms5734 |
0.301 |
|
2014 |
Liedtke W, Zhang JY, Hall RP, Steinhoff M. Keratinocyte growth regulation TRP-ed up over downregulated TRPV4? The Journal of Investigative Dermatology. 134: 2310-2. PMID 25120148 DOI: 10.1038/Jid.2014.250 |
0.31 |
|
2014 |
Zhao P, Lieu T, Barlow N, Metcalf M, Veldhuis NA, Jensen DD, Kocan M, Sostegni S, Haerteis S, Baraznenok V, Henderson I, Lindström E, Guerrero-Alba R, Valdez-Morales EE, Liedtke W, et al. Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4. The Journal of Biological Chemistry. 289: 27215-34. PMID 25118282 DOI: 10.1074/Jbc.M114.599712 |
0.363 |
|
2014 |
Leddy HA, McNulty AL, Lee SH, Rothfusz NE, Gloss B, Kirby ML, Hutson MR, Cohn DH, Guilak F, Liedtke W. Follistatin in chondrocytes: the link between TRPV4 channelopathies and skeletal malformations. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2525-37. PMID 24577120 DOI: 10.1096/Fj.13-245936 |
0.505 |
|
2014 |
O'Conor CJ, Leddy HA, Benefield HC, Liedtke WB, Guilak F. TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading. Proceedings of the National Academy of Sciences of the United States of America. 111: 1316-21. PMID 24474754 DOI: 10.1073/Pnas.1319569111 |
0.539 |
|
2014 |
Chen Y, Guilak F, Gereau IV RW, Wang F, Liedtke W. TRPV4-mediated trigeminal pain: behavior assessments and mechanisms Molecular Pain. 10: P1. DOI: 10.1186/1744-8069-10-S1-P1 |
0.574 |
|
2014 |
Chen Y, Wang F, Liedtke W. Modeling TMJD pain in the laboratory mouse: role of TRP ion channels Molecular Pain. 10: O8. DOI: 10.1186/1744-8069-10-S1-O8 |
0.438 |
|
2014 |
Lee W, Leddy H, Guilak F, Liedtke W. Characterization of Mechanotransensitivity of Articular Chondrocytes Biophysical Journal. 106: 389a-390a. DOI: 10.1016/J.Bpj.2013.11.2202 |
0.758 |
|
2013 |
Yeo M, Patisaul H, Liedtke W. Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity. Epigenetics : Official Journal of the Dna Methylation Society. 8: 1128-32. PMID 24071811 DOI: 10.4161/Epi.26406 |
0.318 |
|
2013 |
Moore C, Cevikbas F, Pasolli HA, Chen Y, Kong W, Kempkes C, Parekh P, Lee SH, Kontchou NA, Yeh I, Ye I, Jokerst NM, Fuchs E, Steinhoff M, Liedtke WB. UVB radiation generates sunburn pain and affects skin by activating epidermal TRPV4 ion channels and triggering endothelin-1 signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: E3225-34. PMID 23929777 DOI: 10.1073/Pnas.1312933110 |
0.357 |
|
2013 |
Xia Y, Fu Z, Hu J, Huang C, Paudel O, Cai S, Liedtke W, Sham JS. TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension. American Journal of Physiology. Cell Physiology. 305: C704-15. PMID 23739180 DOI: 10.1152/Ajpcell.00099.2013 |
0.329 |
|
2013 |
Chen Y, Williams SH, McNulty AL, Hong JH, Lee SH, Rothfusz NE, Parekh PK, Moore C, Gereau RW, Taylor AB, Wang F, Guilak F, Liedtke W. Temporomandibular joint pain: a critical role for Trpv4 in the trigeminal ganglion. Pain. 154: 1295-304. PMID 23726674 DOI: 10.1016/J.Pain.2013.04.004 |
0.561 |
|
2013 |
Fariss MW, Gilmour MI, Reilly CA, Liedtke W, Ghio AJ. Emerging mechanistic targets in lung injury induced by combustion-generated particles. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 253-67. PMID 23322347 DOI: 10.1093/Toxsci/Kft001 |
0.318 |
|
2013 |
Poole DP, Amadesi S, Veldhuis NA, Abogadie FC, Lieu T, Darby W, Liedtke W, Lew MJ, McIntyre P, Bunnett NW. Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling. The Journal of Biological Chemistry. 288: 5790-802. PMID 23288842 DOI: 10.1074/Jbc.M112.438184 |
0.459 |
|
2013 |
Liedtke W, Yeo M, Zhang H, Wang Y, Gignac M, Miller S, Berglund K, Liu J. Highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter KCC2. Small (Weinheim An Der Bergstrasse, Germany). 9: 1066-75. PMID 23229576 DOI: 10.1002/Smll.201201994 |
0.348 |
|
2013 |
O'Conor CJ, Griffin TM, Liedtke W, Guilak F. Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet. Annals of the Rheumatic Diseases. 72: 300-4. PMID 23178209 DOI: 10.1136/Annrheumdis-2012-202272 |
0.513 |
|
2013 |
O'Conor C, Benefield H, Liedtke W, Guilak F. The transient receptor potential vanilloid 4 ion channel regulates the biosynthetic response of chondrocytes to dynamic loading Osteoarthritis and Cartilage. 21: S17-S18. DOI: 10.1016/J.Joca.2013.02.057 |
0.576 |
|
2012 |
Ye L, Kleiner S, Wu J, Sah R, Gupta RK, Banks AS, Cohen P, Khandekar MJ, Boström P, Mepani RJ, Laznik D, Kamenecka TM, Song X, Liedtke W, Mootha VK, et al. TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis. Cell. 151: 96-110. PMID 23021218 DOI: 10.1016/J.Cell.2012.08.034 |
0.342 |
|
2012 |
Sonkusare SK, Bonev AD, Ledoux J, Liedtke W, Kotlikoff MI, Heppner TJ, Hill-Eubanks DC, Nelson MT. Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function. Science (New York, N.Y.). 336: 597-601. PMID 22556255 DOI: 10.1126/Science.1216283 |
0.435 |
|
2012 |
Bourque CW, Guilak F, Liedtke W. A TRP that makes us feel hyper. The Journal of Physiology. 590: 1779-80. PMID 22532645 DOI: 10.1113/Jphysiol.2012.229187 |
0.458 |
|
2012 |
Yang XR, Lin AH, Hughes JM, Flavahan NA, Cao YN, Liedtke W, Sham JS. Upregulation of osmo-mechanosensitive TRPV4 channel facilitates chronic hypoxia-induced myogenic tone and pulmonary hypertension. American Journal of Physiology. Lung Cellular and Molecular Physiology. 302: L555-68. PMID 22207590 DOI: 10.1152/Ajplung.00005.2011 |
0.321 |
|
2012 |
Lange T, Princk M, Zhang Y, Pritschow BW, Teucher S, Liedtke W, Brinkmeier H. TRPV4 Channels in Mouse Skeletal Muscle: Gene Expression, Role for Ca2+ Homeostasis and Muscle Force and Fatigue Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.1878 |
0.326 |
|
2011 |
Ciura S, Liedtke W, Bourque CW. Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14669-76. PMID 21994383 DOI: 10.1523/Jneurosci.1420-11.2011 |
0.4 |
|
2011 |
Ryskamp DA, Witkovsky P, Barabas P, Huang W, Koehler C, Akimov NP, Lee SH, Chauhan S, Xing W, RenterÃa RC, Liedtke W, Krizaj D. The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7089-101. PMID 21562271 DOI: 10.1523/Jneurosci.0359-11.2011 |
0.409 |
|
2011 |
Li J, Kanju P, Patterson M, Chew WL, Cho SH, Gilmour I, Oliver T, Yasuda R, Ghio A, Simon SA, Liedtke W. TRPV4-mediated calcium influx into human bronchial epithelia upon exposure to diesel exhaust particles. Environmental Health Perspectives. 119: 784-93. PMID 21245013 DOI: 10.1289/Ehp.1002807 |
0.346 |
|
2011 |
Pritschow BW, Lange T, Kasch J, Kunert-Keil C, Liedtke W, Brinkmeier H. Functional TRPV4 channels are expressed in mouse skeletal muscle and can modulate resting Ca2+ influx and muscle fatigue. Pflugers Archiv : European Journal of Physiology. 461: 115-22. PMID 20924600 DOI: 10.1007/S00424-010-0883-4 |
0.334 |
|
2011 |
Zaelzer CA, Hua P, Prager-Khoutorsky M, Ciura S, Lee S, Liedtke W, Bourque CW. TRPV1Δ1-283: A Candidate Osmoreceptor Channel Biophysical Journal. 100: 280a. DOI: 10.1016/J.Bpj.2010.12.1738 |
0.421 |
|
2010 |
Shukla AK, Kim J, Ahn S, Xiao K, Shenoy SK, Liedtke W, Lefkowitz RJ. Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. The Journal of Biological Chemistry. 285: 30115-25. PMID 20650893 DOI: 10.1074/Jbc.M110.141549 |
0.393 |
|
2010 |
Clark AL, Votta BJ, Kumar S, Liedtke W, Guilak F. Chondroprotective role of the osmotically sensitive ion channel transient receptor potential vanilloid 4: age- and sex-dependent progression of osteoarthritis in Trpv4-deficient mice. Arthritis and Rheumatism. 62: 2973-83. PMID 20583100 DOI: 10.1002/Art.27624 |
0.589 |
|
2010 |
Hamanaka K, Jian MY, Townsley MI, King JA, Liedtke W, Weber DS, Eyal FG, Clapp MM, Parker JC. TRPV4 channels augment macrophage activation and ventilator-induced lung injury. American Journal of Physiology. Lung Cellular and Molecular Physiology. 299: L353-62. PMID 20562229 DOI: 10.1152/Ajplung.00315.2009 |
0.333 |
|
2010 |
Ceppa E, Cattaruzza F, Lyo V, Amadesi S, Pelayo JC, Poole DP, Vaksman N, Liedtke W, Cohen DM, Grady EF, Bunnett NW, Kirkwood KS. Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 299: G556-71. PMID 20539005 DOI: 10.1152/Ajpgi.00433.2009 |
0.42 |
|
2010 |
Guilak F, Leddy HA, Liedtke W. Transient receptor potential vanilloid 4: The sixth sense of the musculoskeletal system? Annals of the New York Academy of Sciences. 1192: 404-9. PMID 20392266 DOI: 10.1111/J.1749-6632.2010.05389.X |
0.624 |
|
2010 |
Vergnolle N, Cenac N, Altier C, Cellars L, Chapman K, Zamponi GW, Materazzi S, Nassini R, Liedtke W, Cattaruzza F, Grady EF, Geppetti P, Bunnett NW. A role for transient receptor potential vanilloid 4 in tonicity-induced neurogenic inflammation. British Journal of Pharmacology. 159: 1161-73. PMID 20136846 DOI: 10.1111/J.1476-5381.2009.00590.X |
0.376 |
|
2010 |
Fields WR, Liedtke W, Li J, Bombick B. Abstract 1693: Assessment of Nrf2 luciferase reporter assay and heme oxygenase expression as models of oxidative stress inin vitrocultures of lung cells exposed to cigarette smoke condensate Cancer Research. 70: 1693-1693. DOI: 10.1158/1538-7445.Am10-1693 |
0.305 |
|
2009 |
Phan MN, Leddy HA, Votta BJ, Kumar S, Levy DS, Lipshutz DB, Lee SH, Liedtke W, Guilak F. Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes. Arthritis and Rheumatism. 60: 3028-37. PMID 19790068 DOI: 10.1002/Art.24799 |
0.581 |
|
2009 |
Earley S, Pauyo T, Drapp R, Tavares MJ, Liedtke W, Brayden JE. TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1096-102. PMID 19617407 DOI: 10.1152/Ajpheart.00241.2009 |
0.357 |
|
2009 |
Wu S, Jian MY, Xu YC, Zhou C, Al-Mehdi AB, Liedtke W, Shin HS, Townsley MI. Ca2+ entry via alpha1G and TRPV4 channels differentially regulates surface expression of P-selectin and barrier integrity in pulmonary capillary endothelium. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L650-7. PMID 19617313 DOI: 10.1152/Ajplung.00015.2009 |
0.405 |
|
2009 |
Guilak F, Cohen DM, Estes BT, Gimble JM, Liedtke W, Chen CS. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell. 5: 17-26. PMID 19570510 DOI: 10.1016/J.Stem.2009.06.016 |
0.455 |
|
2008 |
Liedtke W. Molecular mechanisms of TRPV4-mediated neural signaling. Annals of the New York Academy of Sciences. 1144: 42-52. PMID 19076362 DOI: 10.1196/Annals.1418.012 |
0.448 |
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2008 |
Lorenzo IM, Liedtke W, Sanderson MJ, Valverde MA. TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 12611-6. PMID 18719094 DOI: 10.1073/Pnas.0803970105 |
0.429 |
|
2008 |
Simon SA, Liedtke W. How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways. The Journal of Clinical Investigation. 118: 2383-6. PMID 18568080 DOI: 10.1172/Jci36111 |
0.303 |
|
2008 |
Cenac N, Altier C, Chapman K, Liedtke W, Zamponi G, Vergnolle N. Transient Receptor Potential Vanilloid-4 Has a Major Role in Visceral Hypersensitivity Symptoms Gastroenterology. 135. PMID 18565335 DOI: 10.1053/J.Gastro.2008.05.024 |
0.41 |
|
2008 |
Brierley SM, Page AJ, Hughes PA, Adam B, Liebregts T, Cooper NJ, Holtmann G, Liedtke W, Blackshaw LA. Selective role for TRPV4 ion channels in visceral sensory pathways. Gastroenterology. 134: 2059-69. PMID 18343379 DOI: 10.1053/J.Gastro.2008.01.074 |
0.427 |
|
2008 |
Sipe WE, Brierley SM, Martin CM, Phillis BD, Cruz FB, Grady EF, Liedtke W, Cohen DM, Vanner S, Blackshaw LA, Bunnett NW. Transient receptor potential vanilloid 4 mediates protease activated receptor 2-induced sensitization of colonic afferent nerves and visceral hyperalgesia. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1288-98. PMID 18325985 DOI: 10.1152/Ajpgi.00002.2008 |
0.359 |
|
2008 |
Yin J, Hoffmann J, Kaestle SM, Neye N, Wang L, Baeurle J, Liedtke W, Wu S, Kuppe H, Pries AR, Kuebler WM. Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4. Circulation Research. 102: 966-74. PMID 18323527 DOI: 10.1161/Circresaha.107.168724 |
0.372 |
|
2008 |
Jian MY, King JA, Al-Mehdi AB, Liedtke W, Townsley MI. High vascular pressure-induced lung injury requires P450 epoxygenase-dependent activation of TRPV4. American Journal of Respiratory Cell and Molecular Biology. 38: 386-92. PMID 17962608 DOI: 10.1165/Rcmb.2007-0192Oc |
0.328 |
|
2008 |
Leddy H, Phan M, Votta B, Kumar S, Lee S, Liedtke W, Guilak F. A6 FUNCTIONAL CHARACTERIZATION OF TRPV4 AS AN OSMOTICALLY SENSITIVE ION CHANNEL IN ARTICULAR CHONDROCYTES Osteoarthritis and Cartilage. 16: S15-S16. DOI: 10.1016/S1063-4584(08)60052-7 |
0.526 |
|
2008 |
Ceppa EP, Cattaruzza F, Amadesi S, Vaksman N, Grady E, Liedtke W, Bunnett NW, Kirkwood KS. 512 The Transient Receptor Potential (Trp) Ion Channels TRPA1 and TRPV4 Mediate Inflammatory Pain in the Pancreas Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)60336-4 |
0.424 |
|
2008 |
Liedtke W. TRPV Ion Channels and Sensory Transduction of Osmotic and Mechanical Stimuli in Mammals [Sic]. 11: 85-100. DOI: 10.1007/978-3-540-72739-2_5 |
0.423 |
|
2007 |
Gevaert T, Vriens J, Segal A, Everaerts W, Roskams T, Talavera K, Owsianik G, Liedtke W, Daelemans D, Dewachter I, Van Leuven F, Voets T, De Ridder D, Nilius B. Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding. The Journal of Clinical Investigation. 117: 3453-62. PMID 17948126 DOI: 10.1172/Jci31766 |
0.415 |
|
2007 |
Hartmannsgruber V, Heyken WT, Kacik M, Kaistha A, Grgic I, Harteneck C, Liedtke W, Hoyer J, Köhler R. Arterial response to shear stress critically depends on endothelial TRPV4 expression. Plos One. 2: e827. PMID 17786199 DOI: 10.1371/Journal.Pone.0000827 |
0.309 |
|
2007 |
Hamanaka K, Jian MY, Weber DS, Alvarez DF, Townsley MI, Al-Mehdi AB, King JA, Liedtke W, Parker JC. TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L923-32. PMID 17660328 DOI: 10.1152/Ajplung.00221.2007 |
0.343 |
|
2007 |
Liu L, Chen L, Liedtke W, Simon SA. Changes in osmolality sensitize the response to capsaicin in trigeminal sensory neurons Journal of Neurophysiology. 97: 2001-2015. PMID 17353553 DOI: 10.1152/Jn.00887.2006 |
0.393 |
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2007 |
Liedtke W. Role of TRPV ion channels in sensory transduction of osmotic stimuli in mammals. Experimental Physiology. 92: 507-12. PMID 17350992 DOI: 10.1113/Expphysiol.2006.035642 |
0.427 |
|
2007 |
Liedtke W. TRPV channels' role in osmotransduction and mechanotransduction. Handbook of Experimental Pharmacology. 179: 473-487. PMID 17217074 DOI: 10.1007/978-3-540-34891-7_28 |
0.424 |
|
2007 |
Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, et al. Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice. The Journal of Physiology. 578: 715-33. PMID 17124270 DOI: 10.1113/Jphysiol.2006.121111 |
0.342 |
|
2006 |
Liedtke W. Transient receptor potential vanilloid channels functioning in transduction of osmotic stimuli. The Journal of Endocrinology. 191: 515-23. PMID 17170210 DOI: 10.1677/Joe.1.07000 |
0.419 |
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2006 |
Alvarez DF, King JA, Weber D, Addison E, Liedtke W, Townsley MI. Transient receptor potential vanilloid 4-mediated disruption of the alveolar septal barrier: a novel mechanism of acute lung injury. Circulation Research. 99: 988-95. PMID 17008604 DOI: 10.1161/01.Res.0000247065.11756.19 |
0.395 |
|
2006 |
Liu X, Bandyopadhyay BC, Bandyopadhyay B, Nakamoto T, Singh B, Liedtke W, Melvin JE, Ambudkar I. A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery. The Journal of Biological Chemistry. 281: 15485-95. PMID 16571723 DOI: 10.1074/Jbc.M600549200 |
0.381 |
|
2005 |
Liedtke W, Kim C. Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon! Cellular and Molecular Life Sciences. 62: 2985-3001. PMID 16314934 DOI: 10.1007/S00018-005-5181-5 |
0.429 |
|
2005 |
Alessandri-Haber N, Joseph E, Dina OA, Liedtke W, Levine JD. TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator. Pain. 118: 70-9. PMID 16213085 DOI: 10.1016/J.Pain.2005.07.016 |
0.385 |
|
2005 |
Liedtke W. TRPV4 plays an evolutionary conserved role in the transduction of osmotic and mechanical stimuli in live animals. The Journal of Physiology. 567: 53-8. PMID 15961428 DOI: 10.1113/Jphysiol.2005.088963 |
0.452 |
|
2005 |
Liedtke W. TRPV4 as osmosensor: a transgenic approach. Pflugers Archiv : European Journal of Physiology. 451: 176-80. PMID 15952033 DOI: 10.1007/S00424-005-1449-8 |
0.43 |
|
2003 |
Liedtke W, Tobin DM, Bargmann CI, Friedman JM. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Proceedings of the National Academy of Sciences of the United States of America. 100: 14531-6. PMID 14581619 DOI: 10.1073/Pnas.2235619100 |
0.416 |
|
2003 |
Liedtke W, Friedman JM. Abnormal osmotic regulation in trpv4-/- mice. Proceedings of the National Academy of Sciences of the United States of America. 100: 13698-703. PMID 14581612 DOI: 10.1073/Pnas.1735416100 |
0.355 |
|
2000 |
Liedtke W, Choe Y, Martí-Renom MA, Bell AM, Denis CS, Sali A, Hudspeth AJ, Friedman JM, Heller S. Vanilloid receptor-related osmotically activated channel (VR-OAC), a candidate vertebrate osmoreceptor. Cell. 103: 525-35. PMID 11081638 DOI: 10.1016/S0092-8674(00)00143-4 |
0.422 |
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