| Year |
Citation |
Score |
| 2024 |
Yang H, Verhoeve VI, Chandler CE, Nallar S, Snyder GA, Ernst RK, Gillespie JJ. Structural determination of lipid A without chemical extraction confirms shorter acyl chains in later-evolving spotted fever group pathogens. Msphere. e0060923. PMID 38259062 DOI: 10.1128/msphere.00609-23 |
0.381 |
|
| 2023 |
Hofstaedter CE, Chandler CE, Met CM, Gillespie JJ, Harro JM, Goodlett DR, Rasko DA, Ernst RK. Divergent LpxO enzymes perform site-specific lipid A 2-hydroxylation. Mbio. e0282323. PMID 38131669 DOI: 10.1128/mbio.02823-23 |
0.637 |
|
| 2023 |
Mikhael A, Hardie D, Smith D, Pětrošová H, Ernst RK, Goodlett DR. Structural Elucidation of Intact Rough-type Lipopolysaccharides Using Field Asymmetric Ion Mobility Spectrometry and Kendrick Mass Defect Plots. Analytical Chemistry. PMID 37943784 DOI: 10.1021/acs.analchem.3c02947 |
0.643 |
|
| 2023 |
Yang H, Verhoeve VI, Chandler CE, Nallar S, Snyder GA, Ernst RK, Gillespie JJ. Structural determination of lipid A without chemical extraction confirms shorter acyl chains in later-evolving Spotted Fever Group pathogens. Biorxiv : the Preprint Server For Biology. PMID 37461656 DOI: 10.1101/2023.07.06.547954 |
0.356 |
|
| 2023 |
Mikhael A, Hardie D, Smith D, Pětrošová H, Ernst RK, Goodlett DR. Structural Elucidation of Intact Rough-Type Lipopolysaccharides using Field Asymmetric Ion Mobility Spectrometry and Kendrick Mass Defect Plots. Biorxiv : the Preprint Server For Biology. PMID 37461651 DOI: 10.1101/2023.06.21.545950 |
0.648 |
|
| 2023 |
Pětrošová H, Mikhael A, Culos S, Giraud-Gatineau A, Gomez AM, Sherman ME, Ernst RK, Cameron CE, Picardeau M, Goodlett DR. Lipid A structural diversity among members of the genus . Frontiers in Microbiology. 14: 1181034. PMID 37303810 DOI: 10.3389/fmicb.2023.1181034 |
0.686 |
|
| 2023 |
Yang H, Sherman ME, Koo CJ, Treaster LM, Smith JP, Gallaher SG, Goodlett DR, Sweet CR, Ernst RK. Structure Determination of Lipid A with Multiple Glycosylation Sites by Tandem MS of Lithium-Adducted Negative Ions. Journal of the American Society For Mass Spectrometry. PMID 37184080 DOI: 10.1021/jasms.3c00014 |
0.685 |
|
| 2022 |
Välikangas T, Suomi T, Chandler CE, Scott AJ, Tran BQ, Ernst RK, Goodlett DR, Elo LL. Benchmarking tools for detecting longitudinal differential expression in proteomics data allows establishing a robust reproducibility optimization regression approach. Nature Communications. 13: 7877. PMID 36550114 DOI: 10.1038/s41467-022-35564-z |
0.575 |
|
| 2022 |
Sherman ME, Smith RD, Gardner FM, Goodlett DR, Ernst RK. A Sensitive GC-MS Method for Quantitation of Lipid A Backbone Components and Terminal Phosphate Modifications. Journal of the American Society For Mass Spectrometry. PMID 36326685 DOI: 10.1021/jasms.2c00266 |
0.695 |
|
| 2022 |
Yang H, Smith RD, Sumner KP, Goodlett DR, Johnson JK, Ernst RK. A Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry Direct-from-Urine-Specimen Diagnostic for Gram-Negative Pathogens. Microbiology Spectrum. e0373022. PMID 36255333 DOI: 10.1128/spectrum.03730-22 |
0.642 |
|
| 2022 |
Harberts EM, Grubaugh D, Akuma DC, Shin S, Ernst RK, Brodsky IE. Position-Specific Secondary Acylation Determines Detection of Lipid A by Murine TLR4 and Caspase-11. Infection and Immunity. e0020122. PMID 35862717 DOI: 10.1128/iai.00201-22 |
0.37 |
|
| 2022 |
Alexander-Floyd J, Bass AR, Harberts EM, Grubaugh D, Buxbaum JD, Brodsky IE, Ernst RK, Shin S. Lipid A Variants Activate Human TLR4 and the Noncanonical Inflammasome Differently and Require the Core Oligosaccharide for Inflammasome Activation. Infection and Immunity. e0020822. PMID 35862709 DOI: 10.1128/iai.00208-22 |
0.33 |
|
| 2022 |
Yang H, Smith RD, Chandler CE, Johnson JK, Jackson SN, Woods AS, Scott AJ, Goodlett DR, Ernst RK. Lipid A Structural Determination from a Single Colony. Analytical Chemistry. PMID 35576511 DOI: 10.1021/acs.analchem.1c05394 |
0.696 |
|
| 2022 |
Gerster T, Wröbel M, Hofstaedter CE, Schwudke D, Ernst RK, Ranf S, Gisch N. Remodeling of Lipid A in pv. In Vitro. International Journal of Molecular Sciences. 23. PMID 35216122 DOI: 10.3390/ijms23041996 |
0.316 |
|
| 2022 |
Smith RD, McElheny CL, Izac JR, Gardner FM, Chandler CE, Goodlett DR, Doi Y, Johnson JK, Ernst RK. A Novel Lipid-Based MALDI-TOF Assay for the Rapid Detection of Colistin-Resistant Species. Microbiology Spectrum. e0144521. PMID 35107363 DOI: 10.1128/spectrum.01445-21 |
0.662 |
|
| 2021 |
Harberts E, Liang T, Yoon SH, Opene BN, McFarland MA, Goodlett DR, Ernst RK. Correction to "Toll-like Receptor 4-Independent Effects of Lipopolysaccharide Identified Using Longitudinal Serum Proteomics". Journal of Proteome Research. PMID 34793171 DOI: 10.1021/acs.jproteome.1c00855 |
0.587 |
|
| 2021 |
Ernst O, Khan MM, Oyler BL, Yoon SH, Sun J, Lin FY, Manes NP, MacKerell AD, Fraser IDC, Ernst RK, Goodlett DR, Nita-Lazar A. Species-Specific Endotoxin Stimulus Determines Toll-Like Receptor 4- and Caspase 11-Mediated Pathway Activation Characteristics. Msystems. e0030621. PMID 34342534 DOI: 10.1128/mSystems.00306-21 |
0.802 |
|
| 2021 |
Chattagul S, Khan MM, Scott AJ, Nita-Lazar A, Ernst RK, Goodlett DR, Sermswan RW. Transcriptomics Analysis Uncovers Transient Ceftazidime Tolerance in Biofilms. Acs Infectious Diseases. PMID 34138549 DOI: 10.1021/acsinfecdis.1c00003 |
0.599 |
|
| 2021 |
Guillotte ML, Chandler CE, Verhoeve VI, Gillespie JJ, Driscoll TP, Rahman MS, Ernst RK, Azad AF. Lipid A Structural Divergence in Pathogens. Msphere. 6. PMID 33952661 DOI: 10.1128/mSphere.00184-21 |
0.375 |
|
| 2021 |
Gauthier AE, Chandler CE, Poli V, Gardner FM, Tekiau A, Smith R, Bonham KS, Cordes EE, Shank TM, Zanoni I, Goodlett DR, Biller SJ, Ernst RK, Rotjan RD, Kagan JC. Deep-sea microbes as tools to refine the rules of innate immune pattern recognition. Science Immunology. 6. PMID 33712473 DOI: 10.1126/sciimmunol.abe0531 |
0.648 |
|
| 2020 |
Sorensen M, Chandler CE, Gardner FM, Ramadan S, Khot PD, Leung LM, Farrance CE, Goodlett DR, Ernst RK, Nilsson E. Rapid microbial identification and colistin resistance detection via MALDI-TOF MS using a novel on-target extraction of membrane lipids. Scientific Reports. 10: 21536. PMID 33299017 DOI: 10.1038/s41598-020-78401-3 |
0.695 |
|
| 2020 |
Yang H, Jackson SN, Woods AS, Goodlett DR, Ernst RK, Scott AJ. Streamlined Analysis of Cardiolipins in Prokaryotic and Eukaryotic Samples Using Norharmane Matrix by MALDI-MSI. Journal of the American Society For Mass Spectrometry. PMID 32924474 DOI: 10.1021/Jasms.0C00201 |
0.641 |
|
| 2020 |
Yang H, Chandler CE, Jackson SN, Woods AS, Goodlett DR, Ernst RK, Scott AJ. On-tissue derivatization of lipopolysaccharide for detection of lipid A using MALDI-MSI. Analytical Chemistry. PMID 32902263 DOI: 10.1021/Acs.Analchem.0C02566 |
0.725 |
|
| 2020 |
Chandler CE, Harberts EM, Pelletier MR, Thaipisuttikul I, Jones JW, Hajjar AM, Sahl JW, Goodlett DR, Pride AC, Rasko DA, Trent MS, Bishop RE, Ernst RK. Early evolutionary loss of the lipid A modifying enzyme PagP resulting in innate immune evasion in . Proceedings of the National Academy of Sciences of the United States of America. PMID 32868431 DOI: 10.1073/Pnas.1917504117 |
0.703 |
|
| 2020 |
Leus IV, Adamiak J, Trinh AN, Smith RD, Smith L, Richardson S, Ernst RK, Zgurskaya HI. Inactivation of AdeABC and AdeIJK efflux pumps elicits specific nonoverlapping transcriptional and phenotypic responses in Acinetobacter baumannii. Molecular Microbiology. PMID 32858760 DOI: 10.1111/Mmi.14594 |
0.336 |
|
| 2020 |
Reinhard J, Mattes C, Väth K, Radanović T, Surma MA, Klose C, Ernst R. A Quantitative Analysis of Cellular Lipid Compositions During Acute Proteotoxic ER Stress Reveals Specificity in the Production of Asymmetric Lipids. Frontiers in Cell and Developmental Biology. 8: 756. PMID 32850859 DOI: 10.3389/Fcell.2020.00756 |
0.362 |
|
| 2020 |
Mattingly AE, Cox K, Smith R, Melander RJ, Ernst RK, Melander C. Screening an established natural product library identifies secondary metabolites that potentiate conventional antibiotics. Acs Infectious Diseases. PMID 32810395 DOI: 10.1021/Acsinfecdis.0C00259 |
0.336 |
|
| 2020 |
Perault AI, Chandler CE, Rasko DA, Ernst RK, Wolfgang MC, Cotter PA. Host Adaptation Predisposes Pseudomonas aeruginosa to Type VI Secretion System-Mediated Predation by the Burkholderia cepacia Complex. Cell Host & Microbe. PMID 32755549 DOI: 10.1016/J.Chom.2020.06.019 |
0.32 |
|
| 2020 |
Brao KJ, Wille BP, Lieberman J, Ernst RK, Shirtliff ME, Harro JM. -transgenic BALB/c mice as a model of infections of the cystic fibrosis lung. Infection and Immunity. PMID 32631918 DOI: 10.1128/Iai.00237-20 |
0.3 |
|
| 2020 |
Richard K, Perkins DJ, Harberts EM, Song Y, Gopalakrishnan A, Shirey KA, Lai W, Vlk A, Mahurkar A, Nallar S, Hawkins LD, Ernst RK, Vogel SN. Dissociation of TRIF bias and adjuvanticity. Vaccine. PMID 32389496 DOI: 10.1016/J.Vaccine.2020.04.042 |
0.382 |
|
| 2020 |
Ryu SY, Wendt GA, Ernst RK, Goodlett DR. MGMS2: Membrane Glycolipid Mass Spectrum Simulator for polymicrobial samples. Rapid Communications in Mass Spectrometry : Rcm. e8824. PMID 32384576 DOI: 10.1002/Rcm.8824 |
0.646 |
|
| 2020 |
Cetuk H, Maramba J, Britt M, Scott AJ, Ernst RK, Mihailescu M, Cotten ML, Sukharev S. Differential interactions of Piscidins with phospholipids and lipopolysaccharides at membrane interfaces. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 32306736 DOI: 10.1021/Acs.Langmuir.0C00017 |
0.372 |
|
| 2020 |
Heinrich F, Salyapongse A, Kumagai A, Dupuy FG, Shukla K, Penk A, Huster D, Ernst RK, Pavlova A, Gumbart JC, Deslouches B, Di YP, Tristram-Nagle S. Synergistic Biophysical Techniques Reveal Structural Mechanisms of Engineered Cationic Antimicrobial Peptides in Lipid Model Membranes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32166806 DOI: 10.1002/Chem.202000212 |
0.352 |
|
| 2020 |
Levental KR, Malmberg E, Symons JL, Fan YY, Chapkin RS, Ernst R, Levental I. Lipidomic and biophysical homeostasis of mammalian membranes counteracts dietary lipid perturbations to maintain cellular fitness. Nature Communications. 11: 1339. PMID 32165635 DOI: 10.1038/S41467-020-15203-1 |
0.357 |
|
| 2020 |
Harberts E, Liang T, Yoon SH, Opene BN, McFarland MA, Goodlett DR, Ernst RK. TLR4-Independent Effects of LPS Identified Using Longitudinal Serum Proteomics. Journal of Proteome Research. PMID 32037835 DOI: 10.1021/Acs.Jproteome.9B00765 |
0.684 |
|
| 2020 |
Ballweg S, Sezgin E, Doktorova M, Covino R, Reinhard J, Wunnicke D, Hänelt I, Levental I, Hummer G, Ernst R. Regulation of lipid saturation without sensing membrane fluidity. Nature Communications. 11: 756. PMID 32029718 DOI: 10.1038/S41467-020-14528-1 |
0.372 |
|
| 2020 |
Levental KR, Symons JL, Fan Y, Chapkin R, Ernst R, Levental I. Homeoviscous Adaptation in Mammalian Cell Membranes in Response to Dietary Lipid Perturbations is Necessary for Cell Survival Biophysical Journal. 118: 77a. DOI: 10.1016/J.Bpj.2019.11.595 |
0.323 |
|
| 2020 |
Cetuk H, Maramba J, Britt M, Ernst RK, Mihailescu E, Cotten M, Sukharev SI. Piscidins at Membrane Interfaces: Phospholipids versus LPS Biophysical Journal. 118: 238a. DOI: 10.1016/J.Bpj.2019.11.1402 |
0.361 |
|
| 2019 |
Crépin S, Ottosen EN, Chandler CE, Sintsova A, Ernst RK, Mobley HLT. The UDP-GalNAcA biosynthesis genes gna-gne2 are required to maintain cell envelope integrity and in vivo fitness in multi-drug resistant Acinetobacter baumannii. Molecular Microbiology. PMID 31680352 DOI: 10.1111/Mmi.14407 |
0.384 |
|
| 2019 |
Sengyee S, Yoon SH, West TE, Ernst RK, Chantratita N. Lipopolysaccharides of different species with different lipid A structures induce TLR4 activation and react with melioidosis patient sera. Infection and Immunity. PMID 31548320 DOI: 10.1128/Iai.00692-19 |
0.434 |
|
| 2019 |
Krishnamoorthy G, Weeks JW, Zhang Z, Chandler C, Xue H, Schweizer HP, Ernst RK, Zgurskaya HI. Efflux pumps of control the permeability barrier of the outer membrane. Antimicrobial Agents and Chemotherapy. PMID 31383661 DOI: 10.1128/Aac.00956-19 |
0.424 |
|
| 2019 |
Ryu SY, Wendt GA, Chandler CE, Ernst RK, Goodlett DR. Model-based Spectral Library Approach for Bacterial Identification via Membrane Glycolipids. Analytical Chemistry. PMID 31369253 DOI: 10.1021/Acs.Analchem.9B03340 |
0.696 |
|
| 2019 |
Martin S, Melander RJ, Brackett C, Scott AJ, Chandler CE, Nguyen C, Minrovic B, Harrill S, Ernst RK, Manoil C, Melander C. Small Molecule Potentiation of Gram-positive Selective Antibiotics Against Acinetobacter baumannii. Acs Infectious Diseases. PMID 31002491 DOI: 10.1021/Acsinfecdis.9B00067 |
0.382 |
|
| 2019 |
Kutschera A, Dawid C, Gisch N, Schmid C, Raasch L, Gerster T, Schäffer M, Smakowska-Luzan E, Belkhadir Y, Vlot AC, Chandler CE, Schellenberger R, Schwudke D, Ernst RK, Dorey S, et al. Bacterial medium-chain 3-hydroxy fatty acid metabolites trigger immunity in plants. Science (New York, N.Y.). 364: 178-181. PMID 30975887 DOI: 10.1126/Science.Aau1279 |
0.372 |
|
| 2019 |
Barker WT, Chandler CE, Melander RJ, Ernst RK, Melander C. Tryptamine derivatives disarm colistin resistance in polymyxin-resistant gram-negative bacteria. Bioorganic & Medicinal Chemistry. PMID 30898435 DOI: 10.1016/J.Bmc.2019.03.019 |
0.328 |
|
| 2019 |
Cooke AC, Nello AV, Ernst RK, Schertzer JW. Analysis of Pseudomonas aeruginosa biofilm membrane vesicles supports multiple mechanisms of biogenesis. Plos One. 14: e0212275. PMID 30763382 DOI: 10.1371/Journal.Pone.0212275 |
0.366 |
|
| 2019 |
Khan MM, Chattagul S, Tran BQ, Freiberg JA, Nita-Lazar A, Shirtliff ME, Sermswan RW, Ernst RK, Goodlett DR. Temporal proteomic profiling reveals changes that support Burkholderia biofilms. Pathogens and Disease. PMID 30759239 DOI: 10.1093/Femspd/Ftz005 |
0.681 |
|
| 2019 |
Kumagai A, Dupuy FG, Arsov Z, Elhady Y, Moody D, Ernst RK, Deslouches B, Montelaro RC, Peter Di Y, Tristram-Nagle S. Elastic behavior of model membranes with antimicrobial peptides depends on lipid specificity and d-enantiomers. Soft Matter. PMID 30702120 DOI: 10.1039/C8Sm02180E |
0.37 |
|
| 2018 |
Liang T, Leung LM, Opene B, Fondrie WE, Lee YI, Chandler CE, Yoon SH, Doi Y, Ernst RK, Goodlett DR. Rapid microbial identification and antibiotic resistance detection by mass spectrometric analysis of membrane lipids. Analytical Chemistry. PMID 30571097 DOI: 10.1021/Acs.Analchem.8B02611 |
0.723 |
|
| 2018 |
Leung LM, McElheny CL, Gardner FM, Chandler CE, Bowler SL, Mettus RT, Spychala CN, Fowler EL, Opene BNA, Myers RA, Goodlett DR, Doi Y, Ernst RK. A Prospective Study of Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids. Journal of Clinical Microbiology. PMID 30567747 DOI: 10.1128/Jcm.01100-18 |
0.697 |
|
| 2018 |
Fondrie WE, Liang T, Oyler BL, Leung LM, Ernst RK, Strickland DK, Goodlett DR. Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids. Scientific Reports. 8: 15857. PMID 30367087 DOI: 10.1038/S41598-018-33681-8 |
0.801 |
|
| 2018 |
Mustapha MM, Li B, Pacey MP, Mettus RT, McElheny CL, Marshall CW, Ernst RK, Cooper VS, Doi Y. Phylogenomics of colistin-susceptible and resistant XDR Acinetobacter baumannii. The Journal of Antimicrobial Chemotherapy. PMID 30124845 DOI: 10.1093/Jac/Dky290 |
0.321 |
|
| 2018 |
Covino R, Hummer G, Ernst R. Integrated Functions of Membrane Property Sensors and a Hidden Side of the Unfolded Protein Response. Molecular Cell. 71: 458-467. PMID 30075144 DOI: 10.1016/J.Molcel.2018.07.019 |
0.356 |
|
| 2018 |
Guillotte ML, Gillespie JJ, Chandler CE, Rahman MS, Ernst RK, Azad AF. Lipid A biosynthesis utilizes the late acyltransferase LpxJ for secondary fatty acid addition. Journal of Bacteriology. PMID 30012728 DOI: 10.1128/Jb.00334-18 |
0.48 |
|
| 2018 |
Chandler CE, Harberts EM, Laemmermann T, Zeng Q, Opene BN, Germain RN, Jewell C, Scott AJ, Ernst RK. intradermal delivery of bacteria using microneedle arrays. Infection and Immunity. PMID 29986891 DOI: 10.1128/Iai.00406-18 |
0.317 |
|
| 2018 |
Khan MM, Ernst O, Sun J, Fraser IDC, Ernst RK, Goodlett DR, Nita-Lazar A. Mass spectrometry based structural analysis and systems immunoproteomics strategies for deciphering the host response to endotoxin. Journal of Molecular Biology. PMID 29949751 DOI: 10.1016/J.Jmb.2018.06.032 |
0.724 |
|
| 2018 |
Hofbauer HF, Gecht M, Fischer SC, Seybert A, Frangakis AS, Stelzer EHK, Covino R, Hummer G, Ernst R. The molecular recognition of phosphatidic acid by an amphipathic helix in Opi1. The Journal of Cell Biology. PMID 29941475 DOI: 10.1083/Jcb.201802027 |
0.35 |
|
| 2018 |
Gregg KA, Harberts E, Gardner FM, Pelletier MR, Cayatte C, Yu L, McCarthy MP, Marshall JD, Ernst RK. A lipid A-based TLR4 mimetic effectively adjuvants a Yersinia pestis rF-V1 subunit vaccine in a murine challenge model. Vaccine. PMID 29861179 DOI: 10.1016/J.Vaccine.2018.05.101 |
0.332 |
|
| 2018 |
Ernst R, Ballweg S, Levental I. Cellular mechanisms of physicochemical membrane homeostasis. Current Opinion in Cell Biology. 53: 44-51. PMID 29787971 DOI: 10.1016/J.Ceb.2018.04.013 |
0.336 |
|
| 2018 |
Oyler BL, Khan MM, Smith DF, Harberts EM, Kilgour DPA, Ernst RK, Cross AS, Goodlett DR. Correction to: Top Down Tandem Mass Spectrometric Analysis of a Chemically Modified Rough-Type Lipopolysaccharide Vaccine Candidate. Journal of the American Society For Mass Spectrometry. PMID 29687418 DOI: 10.1007/S13361-018-1960-8 |
0.772 |
|
| 2018 |
Radanović T, Reinhard J, Ballweg S, Pesek K, Ernst R. An Emerging Group of Membrane Property Sensors Controls the Physical State of Organellar Membranes to Maintain Their Identity. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1700250. PMID 29574931 DOI: 10.1002/Bies.201700250 |
0.317 |
|
| 2018 |
Sengyee S, Yoon SH, Paksanont S, Yimthin T, Wuthiekanun V, Limmathurotsakul D, West TE, Ernst RK, Chantratita N. Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation. Plos Neglected Tropical Diseases. 12: e0006287. PMID 29474381 DOI: 10.1371/Journal.Pntd.0006287 |
0.442 |
|
| 2018 |
Oyler BL, Khan MM, Smith DF, Harberts EM, Kilgour DPA, Ernst RK, Cross AS, Goodlett DR. Top Down Tandem Mass Spectrometric Analysis of a Chemically Modified Rough-Type Lipopolysaccharide Vaccine Candidate. Journal of the American Society For Mass Spectrometry. PMID 29464544 DOI: 10.1007/S13361-018-1897-Y |
0.791 |
|
| 2018 |
Liang T, Schneider T, Yoon SH, Oyler BL, Leung LM, Fondrie WE, Yen G, Huang Y, Ernst RK, Nilsson E, Goodlett DR. Optimized surface acoustic wave nebulization facilitates bacterial phenotyping International Journal of Mass Spectrometry. 427: 65-72. DOI: 10.1016/J.Ijms.2017.09.007 |
0.791 |
|
| 2017 |
Crawford MA, Fisher DJ, Leung LM, Lomonaco S, Lascols C, Cannatelli A, Giani T, Rossolini GM, Doi Y, Goodlett DR, Allard MW, Sharma SK, Khan E, Ernst RK, Hughes MA. CXC Chemokines Exhibit Bactericidal Activity against Multidrug-Resistant Gram-Negative Pathogens. Mbio. 8. PMID 29138303 DOI: 10.1128/Mbio.01549-17 |
0.676 |
|
| 2017 |
Scott AJ, Post JM, Lerner R, Ellis SR, Lieberman J, Shirey KA, Heeren RMA, Bindila L, Ernst RK. Host-based lipid inflammation drives pathogenesis in Francisella infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109289 DOI: 10.1073/Pnas.1712887114 |
0.424 |
|
| 2017 |
Hajjar AM, Ernst RK, Yi J, Yam CS, Miller SI. Expression level of human TLR4 rather than sequence is the key determinant of LPS responsiveness. Plos One. 12: e0186308. PMID 29020088 DOI: 10.1371/Journal.Pone.0186308 |
0.34 |
|
| 2017 |
Zhang YF, Han K, Chandler CE, Tjaden B, Ernst RK, Lory S. Probing the sRNA regulatory landscape of P. aeruginosa: post-transcriptional control of determinants of pathogenicity and antibiotic susceptibility. Molecular Microbiology. PMID 28976035 DOI: 10.1111/Mmi.13857 |
0.344 |
|
| 2017 |
Leung LM, Cooper VS, Rasko DA, Guo Q, Pacey MP, McElheny CL, Mettus RT, Yoon SH, Goodlett DR, Ernst RK, Doi Y. Structural modification of LPS in colistin-resistant, KPC-producing Klebsiella pneumoniae. The Journal of Antimicrobial Chemotherapy. PMID 28961916 DOI: 10.1093/Jac/Dkx234 |
0.661 |
|
| 2017 |
Barker WT, Martin SE, Chandler CE, Nguyen TV, Harris TL, Goodell C, Melander RJ, Doi Y, Ernst RK, Melander C. Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria. Bioorganic & Medicinal Chemistry. PMID 28958847 DOI: 10.1016/J.Bmc.2017.08.055 |
0.335 |
|
| 2017 |
Mi W, Li Y, Yoon SH, Ernst RK, Walz T, Liao M. Structural basis of MsbA-mediated lipopolysaccharide transport. Nature. PMID 28869968 DOI: 10.1038/Nature23649 |
0.395 |
|
| 2017 |
Chandler CE, Ernst RK. Bacterial lipids: powerful modifiers of the innate immune response. F1000research. 6. PMID 28868130 DOI: 10.12688/F1000Research.11388.1 |
0.41 |
|
| 2017 |
Robert CB, Thomson M, Vercellone A, Gardner F, Ernst RK, Larrouy-Maumus G, Nigou J. Mass spectrometry analysis of intact Francisella bacteria identifies lipid A structure remodeling in response to acidic pH stress. Biochimie. PMID 28807561 DOI: 10.1016/J.Biochi.2017.08.008 |
0.502 |
|
| 2017 |
Leung LM, Fondrie WE, Doi Y, Johnson JK, Strickland DK, Ernst RK, Goodlett DR. Identification of the ESKAPE pathogens by mass spectrometric analysis of microbial membrane glycolipids. Scientific Reports. 7: 6403. PMID 28743946 DOI: 10.1038/S41598-017-04793-4 |
0.704 |
|
| 2017 |
Halbleib K, Pesek K, Covino R, Hofbauer HF, Wunnicke D, Hänelt I, Hummer G, Ernst R. Activation of the Unfolded Protein Response by Lipid Bilayer Stress. Molecular Cell. 67: 673-684.e8. PMID 28689662 DOI: 10.1016/J.Molcel.2017.06.012 |
0.341 |
|
| 2017 |
Gregg KA, Harberts E, Gardner FM, Pelletier MR, Cayatte C, Yu L, McCarthy MP, Marshall JD, Ernst RK. Rationally Designed TLR4 Ligands for Vaccine Adjuvant Discovery. Mbio. 8. PMID 28487429 DOI: 10.1128/Mbio.00492-17 |
0.405 |
|
| 2017 |
Liu YY, Chandler CE, Leung LM, McElheny CL, Mettus RT, Shanks RM, Liu JH, Goodlett DR, Ernst RK, Doi Y. Structural Modification of Lipopolysaccharide Conferred by mcr-1 in Gram-Negative ESKAPE Pathogens. Antimicrobial Agents and Chemotherapy. PMID 28373195 DOI: 10.1128/Aac.00580-17 |
0.699 |
|
| 2017 |
Shaw DK, Wang X, Brown LJ, Chávez AS, Reif KE, Smith AA, Scott AJ, McClure EE, Boradia VM, Hammond HL, Sundberg EJ, Snyder GA, Liu L, DePonte K, Villar M, ... ... Ernst RK, et al. Infection-derived lipids elicit an immune deficiency circuit in arthropods. Nature Communications. 8: 14401. PMID 28195158 DOI: 10.1038/Ncomms14401 |
0.375 |
|
| 2017 |
Scott AJ, Oyler BL, Goodlett DR, Ernst RK. Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship. Biochimica Et Biophysica Acta. PMID 28108356 DOI: 10.1016/J.Bbalip.2017.01.004 |
0.805 |
|
| 2017 |
Ballweg S, Ernst R. Control of membrane fluidity: the OLE pathway in focus. Biological Chemistry. 398: 215-228. PMID 27787227 DOI: 10.1515/Hsz-2016-0277 |
0.371 |
|
| 2016 |
Freiberg JA, Le Breton Y, Tran BQ, Scott AJ, Harro JM, Ernst RK, Goo YA, Mongodin EF, Goodlett DR, McIver KS, Shirtliff ME. Global Analysis and Comparison of the Transcriptomes and Proteomes of Group A Streptococcus Biofilms. Msystems. 1. PMID 27933318 DOI: 10.1128/mSystems.00149-16 |
0.619 |
|
| 2016 |
Kilgour DP, Hughes S, Kilgour SL, Mackay CL, Palmblad M, Tran BQ, Goo YA, Ernst RK, Clarke DJ, Goodlett DR. Autopiquer - a Robust and Reliable Peak Detection Algorithm for Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 27924495 DOI: 10.1007/S13361-016-1549-Z |
0.627 |
|
| 2016 |
Corey BW, Thompson MG, Hittle LE, Jacobs AC, Asafo-Adjei EA, Huggins W, Melander RJ, Melander C, Ernst RK, Zurawski DV. 1, 2, 4 -Triazolidine-3-thiones have specific activity against Acinetobacter baumannii amongst common nosocomial pathogens. Acs Infectious Diseases. PMID 27764938 DOI: 10.1021/Acsinfecdis.6B00133 |
0.38 |
|
| 2016 |
Scott AJ, Flinders B, Cappell J, Liang T, Pelc RS, Tran B, Kilgour DP, Heeren RM, Goodlett DR, Ernst RK. Norharmane Matrix Enhances Detection of Endotoxin by MALDI-MS for Simultaneous Profiling of Pathogen, Host, and Vector Systems. Pathogens and Disease. PMID 27650574 DOI: 10.1093/Femspd/Ftw097 |
0.692 |
|
| 2016 |
Yoon SH, Liang T, Schneider T, Oyler BL, Chandler CE, Ernst RK, Yen GS, Huang Y, Nilsson E, Goodlett DR. Rapid Lipid A Structure Determination via Surface Acoustic Wave Nebulization and Hierarchical Tandem Mass Spectrometry Algorithm. Rapid Communications in Mass Spectrometry : Rcm. PMID 27582344 DOI: 10.1002/Rcm.7728 |
0.775 |
|
| 2016 |
SenGupta S, Hittle LE, Ernst RK, Uriarte SM, Mitchell TC. A Pseudomonas aeruginosa hepta-acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophils. Journal of Leukocyte Biology. PMID 27538572 DOI: 10.1189/Jlb.4Vma0316-101R |
0.364 |
|
| 2016 |
Ernst R, Ejsing CS, Antonny B. Homeoviscous Adaptation and the Regulation of Membrane Lipids. Journal of Molecular Biology. 428: 4776-4791. PMID 27534816 DOI: 10.1016/J.Jmb.2016.08.013 |
0.389 |
|
| 2016 |
Li Y, Yoon SH, Wang X, Ernst RK, Goodlett DR. Structural Derivation of lipid A from Cronobacter sakazakii using Tandem Mass Spectrometry. Rapid Communications in Mass Spectrometry : Rcm. PMID 27502448 DOI: 10.1002/Rcm.7712 |
0.728 |
|
| 2016 |
Brackett CM, Furlani RE, Anderson RG, Krishnamurthy A, Melander RJ, Moskowitz SM, Ernst RK, Melander C. Second Generation Modifiers of Colistin Resistance Show Enhanced Activity and Lower Inherent Toxicity. Tetrahedron. 72: 3549-3553. PMID 27429479 DOI: 10.1016/J.Tet.2015.09.019 |
0.339 |
|
| 2016 |
Maldarelli GA, Piepenbrink KH, Scott AJ, Freiberg JA, Song Y, Achermann Y, Ernst RK, Shirtliff ME, Sundberg EJ, Donnenberg MS, von Rosenvinge EC. Type IV pili promote early biofilm formation by Clostridium difficile. Pathogens and Disease. PMID 27369898 DOI: 10.1093/Femspd/Ftw061 |
0.336 |
|
| 2016 |
Covino R, Ballweg S, Stordeur C, Michaelis JB, Puth K, Wernig F, Bahrami A, Ernst AM, Hummer G, Ernst R. A Eukaryotic Sensor for Membrane Lipid Saturation. Molecular Cell. PMID 27320200 DOI: 10.1016/J.Molcel.2016.05.015 |
0.384 |
|
| 2015 |
Renzi F, Zähringer U, Chandler CE, Ernst RK, Cornelis GR, Ittig SJ. Modification of the 1-phosphate group during biosynthesis of Capnocytophaga canimorsus lipid A. Infection and Immunity. PMID 26644381 DOI: 10.1128/Iai.01006-15 |
0.46 |
|
| 2015 |
Varga JJ, Barbier M, Mulet X, Bielecki P, Bartell JA, Owings JP, Martinez-Ramos I, Hittle LE, Davis MR, Damron FH, Liechti GW, Puchałka J, Dos Santos VA, Ernst RK, Papin JA, et al. Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains. Bmc Genomics. 16: 883. PMID 26519161 DOI: 10.1186/S12864-015-2069-0 |
0.365 |
|
| 2015 |
Chin CY, Gregg KA, Napier BA, Ernst RK, Weiss DS. A PmrB-regulated Deacetylase Required for Lipid A Modification and Polymyxin Resistance in Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. PMID 26459891 DOI: 10.1128/Aac.00515-15 |
0.356 |
|
| 2015 |
Hittle LE, Powell DA, Jones JW, Tofigh M, Goodlett DR, Moskowitz SM, Ernst RK. Site-specific activity of the acyltransferases HtrB1 and HtrB2 in Pseudomonas aeruginosa lipid A biosynthesis. Pathogens and Disease. PMID 26223882 DOI: 10.1093/Femspd/Ftv053 |
0.713 |
|
| 2015 |
Puth K, Hofbauer HF, Sáenz JP, Ernst R. Homeostatic control of biological membranes by dedicated lipid and membrane packing sensors. Biological Chemistry. 396: 1043-58. PMID 25849795 DOI: 10.1515/Hsz-2015-0130 |
0.34 |
|
| 2015 |
Hittle LE, Jones JW, Hajjar AM, Ernst RK, Preston A. Bordetella parapertussis PagP mediates the addition of two palmitates to the lipopolysaccharide lipid A. Journal of Bacteriology. 197: 572-80. PMID 25422302 DOI: 10.1128/Jb.02236-14 |
0.477 |
|
| 2014 |
Knodler LA, Crowley SM, Sham HP, Yang H, Wrande M, Ma C, Ernst RK, Steele-Mortimer O, Celli J, Vallance BA. Noncanonical inflammasome activation of caspase-4/caspase-11 mediates epithelial defenses against enteric bacterial pathogens. Cell Host & Microbe. 16: 249-56. PMID 25121752 DOI: 10.1016/J.Chom.2014.07.002 |
0.357 |
|
| 2014 |
Chirakul S, Bartpho T, Wongsurawat T, Taweechaisupapong S, Karoonutaisiri N, Talaat AM, Wongratanacheewin S, Ernst RK, Sermswan RW. Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model Plos One. 9. PMID 25111708 DOI: 10.1371/Journal.Pone.0104313 |
0.322 |
|
| 2014 |
Pilla DM, Hagar JA, Haldar AK, Mason AK, Degrandi D, Pfeffer K, Ernst RK, Yamamoto M, Miao EA, Coers J. Guanylate binding proteins promote caspase-11-dependent pyroptosis in response to cytoplasmic LPS. Proceedings of the National Academy of Sciences of the United States of America. 111: 6046-51. PMID 24715728 DOI: 10.1073/Pnas.1321700111 |
0.382 |
|
| 2014 |
Rolin O, Muse SJ, Safi C, Elahi S, Gerdts V, Hittle LE, Ernst RK, Harvill ET, Preston A. Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission. Infection and Immunity. 82: 491-9. PMID 24478065 DOI: 10.1128/Iai.01260-12 |
0.441 |
|
| 2014 |
Thaipisuttikul I, Hittle LE, Chandra R, Zangari D, Dixon CL, Garrett TA, Rasko DA, Dasgupta N, Moskowitz SM, Malmström L, Goodlett DR, Miller SI, Bishop RE, Ernst RK. A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis-specific lipid A. Molecular Microbiology. 91: 158-74. PMID 24283944 DOI: 10.1111/Mmi.12451 |
0.714 |
|
| 2014 |
Scott AJ, Jones JW, Orschell CM, Macvittie TJ, Kane MA, Ernst RK. Mass spectrometry imaging enriches biomarker discovery approaches with Candidate mapping Health Physics. 106: 120-128. PMID 24276555 DOI: 10.1097/Hp.0B013E3182A4Ec2F |
0.316 |
|
| 2014 |
Stordeur C, Puth K, Sáenz JP, Ernst R. Crosstalk of lipid and protein homeostasis to maintain membrane function Biological Chemistry. 395: 313-326. PMID 24152902 DOI: 10.1515/Hsz-2013-0235 |
0.37 |
|
| 2014 |
Harris TL, Worthington RJ, Hittle LE, Zurawski DV, Ernst RK, Melander C. Small molecule downregulation of PmrAB reverses lipid a modification and breaks colistin resistance Acs Chemical Biology. 9: 122-127. PMID 24131198 DOI: 10.1021/Cb400490K |
0.362 |
|
| 2013 |
Chantratita N, Tandhavanant S, Myers ND, Seal S, Arayawichanont A, Kliangsa-Ad A, Hittle LE, Ernst RK, Emond MJ, Wurfel MM, Day NP, Peacock SJ, West TE. Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide. Plos One. 8: e81617. PMID 24303060 DOI: 10.1371/Journal.Pone.0081617 |
0.351 |
|
| 2013 |
Li Y, Wang Z, Chen J, Ernst RK, Wang X. Influence of lipid A acylation pattern on membrane permeability and innate immune stimulation. Marine Drugs. 11: 3197-208. PMID 24065161 DOI: 10.3390/Md11093197 |
0.475 |
|
| 2013 |
Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science (New York, N.Y.). 341: 1250-3. PMID 24031018 DOI: 10.1126/Science.1240988 |
0.38 |
|
| 2013 |
Surma MA, Klose C, Peng D, Shales M, Mrejen C, Stefanko A, Braberg H, Gordon DE, Vorkel D, Ejsing CS, Farese R, Simons K, Krogan NJ, Ernst R. A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress. Molecular Cell. 51: 519-30. PMID 23891562 DOI: 10.1016/J.Molcel.2013.06.014 |
0.38 |
|
| 2013 |
Pelletier MR, Casella LG, Jones JW, Adams MD, Zurawski DV, Hazlett KR, Doi Y, Ernst RK. Unique structural modifications are present in the lipopolysaccharide from colistin-resistant strains of Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. 57: 4831-40. PMID 23877686 DOI: 10.1128/Aac.00865-13 |
0.437 |
|
| 2013 |
Nchoutmboube JA, Viktorova EG, Scott AJ, Ford LA, Pei Z, Watkins PA, Ernst RK, Belov GA. Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles. Plos Pathogens. 9: e1003401. PMID 23762027 DOI: 10.1371/Journal.Ppat.1003401 |
0.355 |
|
| 2013 |
Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, et al. The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature. 497: 498-502. PMID 23636320 DOI: 10.1038/Nature12118 |
0.312 |
|
| 2013 |
Rebeil R, Jarrett CO, Driver JD, Ernst RK, Oyston PC, Hinnebusch BJ. Induction of the Yersinia pestis PhoP-PhoQ regulatory system in the flea and its role in producing a transmissible infection. Journal of Bacteriology. 195: 1920-30. PMID 23435973 DOI: 10.1128/Jb.02000-12 |
0.373 |
|
| 2013 |
O'Hara JA, Ambe LA, Casella LG, Townsend BM, Pelletier MR, Ernst RK, Shanks RM, Doi Y. Activities of vancomycin-containing regimens against colistin-resistant Acinetobacter baumannii clinical strains. Antimicrobial Agents and Chemotherapy. 57: 2103-8. PMID 23422916 DOI: 10.1128/Aac.02501-12 |
0.327 |
|
| 2012 |
Powell DA, Li Y, Ernst RK. Turning up Francisella pathogenesis: the LPS thermostat. Virulence. 3: 594-6. PMID 23154289 DOI: 10.4161/Viru.22496 |
0.466 |
|
| 2012 |
Hajjar AM, Ernst RK, Fortuno ES, Brasfield AS, Yam CS, Newlon LA, Kollmann TR, Miller SI, Wilson CB. Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica. Plos Pathogens. 8: e1002963. PMID 23071439 DOI: 10.1371/Journal.Ppat.1002963 |
0.395 |
|
| 2012 |
Yoon SH, Huang Y, Edgar JS, Ting YS, Heron SR, Kao Y, Li Y, Masselon CD, Ernst RK, Goodlett DR. Surface acoustic wave nebulization facilitating lipid mass spectrometric analysis. Analytical Chemistry. 84: 6530-7. PMID 22742654 DOI: 10.1021/Ac300807P |
0.704 |
|
| 2012 |
Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK. LPS remodeling is an evolved survival strategy for bacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 8716-21. PMID 22586119 DOI: 10.1073/Pnas.1202908109 |
0.699 |
|
| 2012 |
Kanistanon D, Powell DA, Hajjar AM, Pelletier MR, Cohen IE, Way SS, Skerrett SJ, Wang X, Raetz CR, Ernst RK. Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses. Infection and Immunity. 80: 943-51. PMID 22215738 DOI: 10.1128/Iai.06109-11 |
0.388 |
|
| 2012 |
Klein KA, Fukuto HS, Pelletier M, Romanov G, Grabenstein JP, Palmer LE, Ernst R, Bliska JB. A transposon site hybridization screen identifies galU and wecBC as important for survival of Yersinia pestis in murine macrophages. Journal of Bacteriology. 194: 653-62. PMID 22139502 DOI: 10.1128/Jb.06237-11 |
0.33 |
|
| 2012 |
Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CRH, Ernst RK. LPS remodeling is an evolved survival strategy for bacteria (Proceedings of the National Academy of Sciences United States of America (2012) 109, (8716-8721) DOI: 10.1073/pnas.1202908109)) Proceedings of the National Academy of Sciences of the United States of America. 109: 13877. DOI: 10.1073/Pnas.1212463109 |
0.63 |
|
| 2011 |
Li Y, Wang X, Ernst RK. A rapid one-step method for the characterization of membrane lipid remodeling in Francisella using matrix-assisted laser desorption ionization time-of-flight tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 25: 2641-8. PMID 23657959 DOI: 10.1002/Rcm.5168 |
0.47 |
|
| 2011 |
Galen JE, Simon R, Ernst RK. Salmonella expressing detoxified lipopolysaccharide is immunogenic and protective both as an attenuated vaccine and for delivery of foreign antigens. Expert Review of Vaccines. 10: 1679-82. PMID 22085171 DOI: 10.1586/Erv.11.155 |
0.301 |
|
| 2011 |
Scott A, Weldon S, Buchanan PJ, Schock B, Ernst RK, McAuley DF, Tunney MM, Irwin CR, Elborn JS, Taggart CC. Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo. Plos One. 6: e26525. PMID 22028895 DOI: 10.1371/Journal.Pone.0026525 |
0.358 |
|
| 2011 |
Simon R, Tennant SM, Wang JY, Schmidlein PJ, Lees A, Ernst RK, Pasetti MF, Galen JE, Levine MM. Salmonella enterica serovar enteritidis core O polysaccharide conjugated to H:g,m flagellin as a candidate vaccine for protection against invasive infection with S. enteritidis. Infection and Immunity. 79: 4240-9. PMID 21807909 DOI: 10.1128/Iai.05484-11 |
0.362 |
|
| 2011 |
MacArthur I, Jones JW, Goodlett DR, Ernst RK, Preston A. Role of pagL and lpxO in Bordetella bronchiseptica lipid A biosynthesis. Journal of Bacteriology. 193: 4726-35. PMID 21764941 DOI: 10.1128/Jb.01502-10 |
0.679 |
|
| 2011 |
Damron FH, Davis MR, Withers TR, Ernst RK, Goldberg JB, Yu G, Yu HD. Vanadate and triclosan synergistically induce alginate production by Pseudomonas aeruginosa strain PAO1. Molecular Microbiology. 81: 554-70. PMID 21631603 DOI: 10.1111/J.1365-2958.2011.07715.X |
0.322 |
|
| 2011 |
Ting YS, Shaffer SA, Jones JW, Ng WV, Ernst RK, Goodlett DR. Automated lipid A structure assignment from hierarchical tandem mass spectrometry data. Journal of the American Society For Mass Spectrometry. 22: 856-66. PMID 21472520 DOI: 10.1007/S13361-010-0055-Y |
0.678 |
|
| 2011 |
Jassem AN, Zlosnik JE, Henry DA, Hancock RE, Ernst RK, Speert DP. In vitro susceptibility of Burkholderia vietnamiensis to aminoglycosides. Antimicrobial Agents and Chemotherapy. 55: 2256-64. PMID 21321142 DOI: 10.1128/Aac.01434-10 |
0.358 |
|
| 2010 |
Soni S, Ernst RK, Muszy?ski A, Mohapatra NP, Perry MB, Vinogradov E, Carlson RW, Gunn JS. Francisella tularensis blue-gray phase variation involves structural modifications of lipopolysaccharide o-antigen, core and lipid a and affects intramacrophage survival and vaccine efficacy. Frontiers in Microbiology. 1: 129. PMID 21687776 DOI: 10.3389/Fmicb.2010.00129 |
0.351 |
|
| 2010 |
Lai XH, Shirley RL, Crosa L, Kanistanon D, Tempel R, Ernst RK, Gallagher LA, Manoil C, Heffron F. Mutations of Francisella novicida that alter the mechanism of its phagocytosis by murine macrophages. Plos One. 5: e11857. PMID 20686600 DOI: 10.1371/Journal.Pone.0011857 |
0.369 |
|
| 2010 |
Moskowitz SM, Ernst RK. The role of Pseudomonas lipopolysaccharide in cystic fibrosis airway infection. Sub-Cellular Biochemistry. 53: 241-53. PMID 20593270 DOI: 10.1007/978-90-481-9078-2_11 |
0.385 |
|
| 2010 |
Jones JW, Cohen IE, Tureĉek F, Goodlett DR, Ernst RK. Comprehensive structure characterization of lipid A extracted from Yersinia pestis for determination of its phosphorylation configuration. Journal of the American Society For Mass Spectrometry. 21: 785-99. PMID 20185334 DOI: 10.1016/J.Jasms.2010.01.008 |
0.653 |
|
| 2009 |
Pilonieta MC, Erickson KD, Ernst RK, Detweiler CS. A protein important for antimicrobial peptide resistance, YdeI/OmdA, is in the periplasm and interacts with OmpD/NmpC. Journal of Bacteriology. 191: 7243-52. PMID 19767429 DOI: 10.1128/Jb.00688-09 |
0.371 |
|
| 2009 |
Buchanan PJ, Ernst RK, Elborn JS, Schock B. Role of CFTR, Pseudomonas aeruginosa and Toll-like receptors in cystic fibrosis lung inflammation. Biochemical Society Transactions. 37: 863-7. PMID 19614608 DOI: 10.1042/Bst0370863 |
0.436 |
|
| 2009 |
Coats SR, Jones JW, Do CT, Braham PH, Bainbridge BW, To TT, Goodlett DR, Ernst RK, Darveau RP. Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities. Cellular Microbiology. 11: 1587-99. PMID 19552698 DOI: 10.1111/J.1462-5822.2009.01349.X |
0.713 |
|
| 2009 |
Berezow AB, Ernst RK, Coats SR, Braham PH, Karimi-Naser LM, Darveau RP. The structurally similar, penta-acylated lipopolysaccharides of Porphyromonas gingivalis and Bacteroides elicit strikingly different innate immune responses. Microbial Pathogenesis. 47: 68-77. PMID 19460428 DOI: 10.1016/J.Micpath.2009.04.015 |
0.468 |
|
| 2009 |
Kalhorn TF, Kiavand A, Cohen IE, Nelson AK, Ernst RK. A sensitive liquid chromatography/mass spectrometry-based assay for quantitation of amino-containing moieties in lipid A. Rapid Communications in Mass Spectrometry : Rcm. 23: 433-42. PMID 19130491 DOI: 10.1002/Rcm.3900 |
0.448 |
|
| 2008 |
Jones JW, Shaffer SA, Ernst RK, Goodlett DR, Turecek F. Determination of pyrophosphorylated forms of lipid A in Gram-negative bacteria using a multivaried mass spectrometric approach. Proceedings of the National Academy of Sciences of the United States of America. 105: 12742-7. PMID 18753624 DOI: 10.1073/Pnas.0800445105 |
0.685 |
|
| 2008 |
West TE, Ernst RK, Jansson-Hutson MJ, Skerrett SJ. Activation of Toll-like receptors by Burkholderia pseudomallei. Bmc Immunology. 9: 46. PMID 18691413 DOI: 10.1186/1471-2172-9-46 |
0.389 |
|
| 2008 |
Bainbridge BW, Karimi-Naser L, Reife R, Blethen F, Ernst RK, Darveau RP. Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid heterogeneity in Porphyromonas gingivalis. Journal of Bacteriology. 190: 4549-58. PMID 18456814 DOI: 10.1128/Jb.00234-08 |
0.356 |
|
| 2008 |
Kanistanon D, Hajjar AM, Pelletier MR, Gallagher LA, Kalhorn T, Shaffer SA, Goodlett DR, Rohmer L, Brittnacher MJ, Skerrett SJ, Ernst RK. A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. Plos Pathogens. 4: e24. PMID 18266468 DOI: 10.1371/Journal.Ppat.0040024 |
0.676 |
|
| 2007 |
Ernst RK, Moskowitz SM, Emerson JC, Kraig GM, Adams KN, Harvey MD, Ramsey B, Speert DP, Burns JL, Miller SI. Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosis. The Journal of Infectious Diseases. 196: 1088-92. PMID 17763333 DOI: 10.1086/521367 |
0.356 |
|
| 2007 |
Rohmer L, Fong C, Abmayr S, Wasnick M, Larson Freeman TJ, Radey M, Guina T, Svensson K, Hayden HS, Jacobs M, Gallagher LA, Manoil C, Ernst RK, Drees B, Buckley D, et al. Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biology. 8: R102. PMID 17550600 DOI: 10.1186/Gb-2007-8-6-R102 |
0.627 |
|
| 2007 |
D'Argenio DA, Wu M, Hoffman LR, Kulasekara HD, Déziel E, Smith EE, Nguyen H, Ernst RK, Larson Freeman TJ, Spencer DH, Brittnacher M, Hayden HS, Selgrade S, Klausen M, Goodlett DR, et al. Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Molecular Microbiology. 64: 512-33. PMID 17493132 DOI: 10.1111/J.1365-2958.2007.05678.X |
0.641 |
|
| 2007 |
Mohapatra NP, Soni S, Bell BL, Warren R, Ernst RK, Muszynski A, Carlson RW, Gunn JS. Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes. Infection and Immunity. 75: 3305-14. PMID 17452468 DOI: 10.1128/Iai.00351-07 |
0.321 |
|
| 2007 |
Murray SR, Ernst RK, Bermudes D, Miller SI, Low KB. pmrA(Con) confers pmrHFIJKL-dependent EGTA and polymyxin resistance on msbB Salmonella by decorating lipid A with phosphoethanolamine. Journal of Bacteriology. 189: 5161-9. PMID 17449614 DOI: 10.1128/Jb.01969-06 |
0.416 |
|
| 2007 |
Shaffer SA, Harvey MD, Goodlett DR, Ernst RK. Structural heterogeneity and environmentally regulated remodeling of Francisella tularensis subspecies novicida lipid A characterized by tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 18: 1080-92. PMID 17446084 DOI: 10.1016/J.Jasms.2007.03.008 |
0.674 |
|
| 2007 |
Gunn JS, Ernst RK. The structure and function of Francisella lipopolysaccharide. Annals of the New York Academy of Sciences. 1105: 202-18. PMID 17395723 DOI: 10.1196/Annals.1409.006 |
0.394 |
|
| 2007 |
Waters VJ, Gómez MI, Soong G, Amin S, Ernst RK, Prince A. Immunostimulatory properties of the emerging pathogen Stenotrophomonas maltophilia. Infection and Immunity. 75: 1698-703. PMID 17220304 DOI: 10.1128/Iai.01469-06 |
0.337 |
|
| 2007 |
Haagensen JA, Klausen M, Ernst RK, Miller SI, Folkesson A, Tolker-Nielsen T, Molin S. Differentiation and distribution of colistin- and sodium dodecyl sulfate-tolerant cells in Pseudomonas aeruginosa biofilms. Journal of Bacteriology. 189: 28-37. PMID 17041046 DOI: 10.1128/Jb.00720-06 |
0.342 |
|
| 2006 |
Hajjar AM, Harvey MD, Shaffer SA, Goodlett DR, Sjöstedt A, Edebro H, Forsman M, Byström M, Pelletier M, Wilson CB, Miller SI, Skerrett SJ, Ernst RK. Lack of in vitro and in vivo recognition of Francisella tularensis subspecies lipopolysaccharide by Toll-like receptors. Infection and Immunity. 74: 6730-8. PMID 16982824 DOI: 10.1128/Iai.00934-06 |
0.689 |
|
| 2006 |
Rebeil R, Ernst RK, Jarrett CO, Adams KN, Miller SI, Hinnebusch BJ. Characterization of late acyltransferase genes of Yersinia pestis and their role in temperature-dependent lipid A variation. Journal of Bacteriology. 188: 1381-8. PMID 16452420 DOI: 10.1128/Jb.188.4.1381-1388.2006 |
0.385 |
|
| 2006 |
Ernst RK, Adams KN, Moskowitz SM, Kraig GM, Kawasaki K, Stead CM, Trent MS, Miller SI. The Pseudomonas aeruginosa lipid A deacylase: selection for expression and loss within the cystic fibrosis airway. Journal of Bacteriology. 188: 191-201. PMID 16352835 DOI: 10.1128/Jb.188.1.191-201.2006 |
0.434 |
|
| 2006 |
Bylund J, Burgess LA, Cescutti P, Ernst RK, Speert DP. Exopolysaccharides from Burkholderia cenocepacia inhibit neutrophil chemotaxis and scavenge reactive oxygen species. The Journal of Biological Chemistry. 281: 2526-32. PMID 16316987 DOI: 10.1074/Jbc.M510692200 |
0.361 |
|
| 2005 |
Ernst R, Klemm R, Schmitt L, Kuchler K. Yeast ATP-binding cassette transporters: cellular cleaning pumps. Methods in Enzymology. 400: 460-84. PMID 16399365 DOI: 10.1016/S0076-6879(05)00026-1 |
0.302 |
|
| 2005 |
Kawasaki K, Ernst RK, Miller SI. Purification and characterization of deacylated and/or palmitoylated lipid A species unique to Salmonella enterica serovar Typhimurium. Journal of Endotoxin Research. 11: 57-61. PMID 15826380 DOI: 10.1179/096805105225006696 |
0.447 |
|
| 2005 |
Tanabe H, Ayabe T, Bainbridge B, Guina T, Ernst RK, Darveau RP, Miller SI, Ouellette AJ. Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria. Infection and Immunity. 73: 2312-20. PMID 15784576 DOI: 10.1128/Iai.73.4.2312-2320.2005 |
0.402 |
|
| 2005 |
Kawasaki K, Ernst RK, Miller SI. Inhibition of Salmonella enterica serovar Typhimurium lipopolysaccharide deacylation by aminoarabinose membrane modification. Journal of Bacteriology. 187: 2448-57. PMID 15774888 DOI: 10.1128/Jb.187.7.2448-2457.2005 |
0.422 |
|
| 2005 |
Beckmann C, Brittnacher M, Ernst R, Mayer-Hamblett N, Miller SI, Burns JL. Use of phage display to identify potential Pseudomonas aeruginosa gene products relevant to early cystic fibrosis airway infections. Infection and Immunity. 73: 444-52. PMID 15618183 DOI: 10.1128/Iai.73.1.444-452.2005 |
0.37 |
|
| 2005 |
Miller SI, Ernst RK, Bader MW. LPS, TLR4 and infectious disease diversity. Nature Reviews. Microbiology. 3: 36-46. PMID 15608698 DOI: 10.1038/Nrmicro1068 |
0.365 |
|
| 2005 |
Kawasaki K, Ernst RK, Miller SI. Purification and characterization of deacylated and/or palmitoylated lipid A species unique to Salmonella enterica serovar Typhimurium Journal of Endotoxin Research. 11: 57-61. DOI: 10.1177/09680519050110010101 |
0.339 |
|
| 2004 |
Kawasaki K, Ernst RK, Miller SI. Deacylation and palmitoylation of lipid A by Salmonellae outer membrane enzymes modulate host signaling through Toll-like receptor 4. Journal of Endotoxin Research. 10: 439-44. PMID 15588428 DOI: 10.1179/096805104225006264 |
0.446 |
|
| 2004 |
Lindgren H, Golovliov I, Baranov V, Ernst RK, Telepnev M, Sjöstedt A. Factors affecting the escape of Francisella tularensis from the phagolysosome. Journal of Medical Microbiology. 53: 953-958. PMID 15358816 DOI: 10.1099/Jmm.0.45685-0 |
0.33 |
|
| 2004 |
Rebeil R, Ernst RK, Gowen BB, Miller SI, Hinnebusch BJ. Variation in lipid A structure in the pathogenic yersiniae. Molecular Microbiology. 52: 1363-73. PMID 15165239 DOI: 10.1111/J.1365-2958.2004.04059.X |
0.426 |
|
| 2004 |
Kawasaki K, Ernst RK, Miller SI. 3-O-deacylation of lipid A by PagL, a PhoP/PhoQ-regulated deacylase of Salmonella typhimurium, modulates signaling through Toll-like receptor 4. The Journal of Biological Chemistry. 279: 20044-8. PMID 15014080 DOI: 10.1074/Jbc.M401275200 |
0.453 |
|
| 2004 |
Moskowitz SM, Ernst RK, Miller SI. PmrAB, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A. Journal of Bacteriology. 186: 575-9. PMID 14702327 DOI: 10.1128/Jb.186.2.575-579.2004 |
0.382 |
|
| 2004 |
Kawasaki K, Ernst RK, Miller SI. Deacylation and palmitoylation of lipid A by Salmonellae outer membrane enzymes modulate host signaling through Toll-like receptor 4 Journal of Endotoxin Research. 10: 439-444. DOI: 10.1177/09680519040100061001 |
0.337 |
|
| 2003 |
Ernst RK, Hajjar AM, Tsai JH, Moskowitz SM, Wilson CB, Miller SI. Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4. Journal of Endotoxin Research. 9: 395-400. PMID 14733728 DOI: 10.1179/096805103225002764 |
0.459 |
|
| 2003 |
Guina T, Wu M, Miller SI, Purvine SO, Yi EC, Eng J, Goodlett DR, Aebersold R, Ernst RK, Lee KA. Proteomic analysis of Pseudomonas aeruginosa grown under magnesium limitation. Journal of the American Society For Mass Spectrometry. 14: 742-51. PMID 12837596 DOI: 10.1016/S1044-0305(03)00133-8 |
0.674 |
|
| 2003 |
Ernst RK, Hajjar AM, Tsai JH, Moskowitz SM, Wilson CB, Miller SI. Pseudomonas aeruginosa lipid A diversity and its recognition by Toll-like receptor 4 Journal of Endotoxin Research. 9: 395-400. DOI: 10.1177/09680519030090060201 |
0.352 |
|
| 2002 |
Brodsky IE, Ernst RK, Miller SI, Falkow S. mig-14 is a Salmonella gene that plays a role in bacterial resistance to antimicrobial peptides. Journal of Bacteriology. 184: 3203-13. PMID 12029036 DOI: 10.1128/Jb.184.12.3203-3213.2002 |
0.376 |
|
| 2002 |
Hajjar AM, Ernst RK, Tsai JH, Wilson CB, Miller SI. Human Toll-like receptor 4 recognizes host-specific LPS modifications. Nature Immunology. 3: 354-9. PMID 11912497 DOI: 10.1038/Ni777 |
0.401 |
|
| 2001 |
Ernst RK, Guina T, Miller SI. Salmonella typhimurium outer membrane remodeling: Role in resistance to host innate immunity Microbes and Infection. 3: 1327-1334. PMID 11755422 DOI: 10.1016/S1286-4579(01)01494-0 |
0.429 |
|
| 2000 |
Gunn JS, Ryan SS, Van Velkinburgh JC, Ernst RK, Miller SI. Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium. Infection and Immunity. 68: 6139-46. PMID 11035717 DOI: 10.1128/Iai.68.11.6139-6146.2000 |
0.395 |
|
| 2000 |
Yethon JA, Gunn JS, Ernst RK, Miller SI, Laroche L, Malo D, Whitfield C. Salmonella enterica serovar typhimurium waaP mutants show increased susceptibility to polymyxin and loss of virulence In vivo. Infection and Immunity. 68: 4485-91. PMID 10899846 DOI: 10.1128/Iai.68.8.4485-4491.2000 |
0.395 |
|
| 2000 |
Gunn JS, Ernst RK, McCoy AJ, Miller SI. Constitutive mutations of the Salmonella enterica serovar Typhimurium transcriptional virulence regulator phoP. Infection and Immunity. 68: 3758-62. PMID 10816543 DOI: 10.1128/Iai.68.6.3758-3762.2000 |
0.352 |
|
| 1999 |
Ernst RK, Yi EC, Guo L, Lim KB, Burns JL, Hackett M, Miller SI. Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa Science. 286: 1561-1565. PMID 10567263 DOI: 10.1126/Science.286.5444.1561 |
0.408 |
|
| 1999 |
Ernst RK, Guina T, Miller SI. How intracellular bacteria survive: Surface modifications that promote resistance to host innate immune responses Journal of Infectious Diseases. 179. PMID 10081503 DOI: 10.1086/513850 |
0.385 |
|
| 1989 |
Abud RL, Lindquist BL, Ernst RK, Merrick JM, Lebenthal E, Lee PC. Concanavalin A Promotes Adherence of Salmonella typhimurium to Small Intestinal Mucosa of Rats Experimental Biology and Medicine. 192: 81-86. DOI: 10.3181/00379727-192-42960 |
0.308 |
|
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