Year |
Citation |
Score |
2020 |
Smith AK, Ropella GEP, McGill MR, Krishnan P, Dutta L, Kennedy RC, Jaeschke H, Hunt CA. Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms. Plos Computational Biology. 16: e1007622. PMID 32484845 DOI: 10.1371/Journal.Pcbi.1007622 |
0.322 |
|
2018 |
Smith AK, Xu Y, Ropella GEP, Hunt CA. A Model Mechanism Based Explanation of an In Vitro-In Vivo Disconnect for Improving Extrapolation and Translation. The Journal of Pharmacology and Experimental Therapeutics. PMID 29434053 DOI: 10.1124/Jpet.117.245019 |
0.3 |
|
2016 |
Petersen BK, Ropella GE, Hunt CA. Virtual Experiments Enable Exploring and Challenging Explanatory Mechanisms of Immune-Mediated P450 Down-Regulation. Plos One. 11: e0155855. PMID 27227433 DOI: 10.1371/Journal.Pone.0155855 |
0.323 |
|
2014 |
Petersen BK, Ropella GEP, Hunt CA. Toward modular biological models: Defining analog modules based on referent physiological mechanisms Bmc Systems Biology. 8. PMID 25123169 DOI: 10.1186/S12918-014-0095-1 |
0.317 |
|
2011 |
Engelberg JA, Datta A, Mostov KE, Hunt CA. MDCK cystogenesis driven by cell stabilization within computational analogues. Plos Computational Biology. 7: e1002030. PMID 21490722 DOI: 10.1371/Journal.Pcbi.1002030 |
0.308 |
|
2011 |
Hunt CA, Ropella GEP. Moving beyond in silico tools to in silico science in support of drug development research Drug Development Research. 72: 153-161. DOI: 10.1002/Ddr.20412 |
0.311 |
|
2010 |
Lam TN, Hunt CA. Mechanistic insight from in silico pharmacokinetic experiments: Roles of P-glycoprotein, Cyp3A4 enzymes, and microenvironments Journal of Pharmacology and Experimental Therapeutics. 332: 398-412. PMID 19864617 DOI: 10.1124/Jpet.109.160739 |
0.319 |
|
2009 |
Hunt CA, Ropella GE, Lam TN, Tang J, Kim SH, Engelberg JA, Sheikh-Bahaei S. At the biological modeling and simulation frontier. Pharmaceutical Research. 26: 2369-400. PMID 19756975 DOI: 10.1007/S11095-009-9958-3 |
0.308 |
|
2009 |
Kim SH, Park S, Mostov K, Debnath J, Hunt CA. Computational investigation of epithelial cell dynamic phenotype in vitro Theoretical Biology and Medical Modelling. 6. PMID 19476639 DOI: 10.1186/1742-4682-6-8 |
0.302 |
|
2009 |
Kim SHJ, Yu W, Mostov K, Matthay MA, Hunt CA. A computational approach to understand in vitro alveolar morphogenesis Plos One. 4. PMID 19283073 DOI: 10.1371/Journal.Pone.0004819 |
0.314 |
|
2009 |
Lam TN, Hunt CA. Discovering plausible mechanistic details of hepatic drug interactions Drug Metabolism and Disposition. 37: 237-246. PMID 18936110 DOI: 10.1124/Dmd.108.023820 |
0.325 |
|
2008 |
Lam TN, Hunt CA. Mechanistic simulations explain paradoxical saquinavir metabolism during in vitro vectorial transport study Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Conference. 5462-5465. PMID 19163953 DOI: 10.1109/IEMBS.2008.4650450 |
0.307 |
|
2008 |
Garmire LX, Hunt CA. In silico methods for unraveling the mechanistic complexities of intestinal absorption: metabolism-efflux transport interactions. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1414-24. PMID 18436618 DOI: 10.1124/Dmd.107.020164 |
0.301 |
|
2008 |
Yan L, Sheihk-Bahaei S, Park S, Ropella GEP, Hunt CA. Predictions of hepatic disposition properties using a mechanistically realistic, physiologically based model Drug Metabolism and Disposition. 36: 759-768. PMID 18227144 DOI: 10.1124/Dmd.107.019067 |
0.312 |
|
2008 |
Yan L, Ropella GEP, Park S, Roberts MS, Hunt CA. Modeling and simulation of hepatic drug disposition using a physiologically based, multi-agent in silico liver Pharmaceutical Research. 25: 1023-1036. PMID 18044012 DOI: 10.1007/S11095-007-9494-Y |
0.316 |
|
1985 |
Hunt CA, Burnette RR, Macgregor RD, Strubbe AE, Lau DT, Taylor N, Kawada H. Synthesis and evaluation of a prototypal artificial red cell Science. 230: 1165-1168. PMID 4071041 DOI: 10.1126/Science.4071041 |
0.652 |
|
1984 |
Hunt CA, Burnette RR. Lipid microencapsulation of hemoglobin Applied Biochemistry and Biotechnology. 10: 147-149. PMID 6524924 DOI: 10.1007/BF02783746 |
0.669 |
|
1983 |
Hunt CA, Burnette RR. Neohemocytes Progress in Clinical and Biological Research. 122: 59-69. PMID 6878382 |
0.653 |
|
1977 |
Garrett ER, Hunt CA. Pharmacokinetics of Δ9-tetrahydrocannabinol in dogs Journal of Pharmaceutical Sciences. 66: 395-407. PMID 845807 DOI: 10.1002/Jps.2600660322 |
0.545 |
|
1977 |
Garrett ER, Hunt CA. Separation and analysis of Δ9 tetrahydrocannabinol in biological fluids by high pressure liquid chromatography and GLC Journal of Pharmaceutical Sciences. 66: 20-26. PMID 833737 DOI: 10.1002/Jps.2600660105 |
0.525 |
|
1976 |
Garrett ER, Hunt CA. Separation and sensitive assay of THC in biological fluids by HPLC and GLC Nida Research Monograph. 33-41. PMID 967239 |
0.481 |
|
1974 |
Garrett ER, Hunt CA. Physicochemical properties, solubility, and protein binding of Δ9 tetrahydrocannabinol Journal of Pharmaceutical Sciences. 63: 1056-1064. PMID 4853640 DOI: 10.1002/Jps.2600630705 |
0.546 |
|
1973 |
Garrett ER, Hunt CA. Picogram analysis of tetrahydrocannabinol and application to biological fluids Journal of Pharmaceutical Sciences. 62: 1211-1214. PMID 4714142 DOI: 10.1002/Jps.2600620740 |
0.496 |
|
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