Year |
Citation |
Score |
2023 |
Meehan RT, Gill MT, Hoffman ED, Coeshott CM, Galvan MD, Wolf ML, Amigues IA, Kastsianok LM, Regan EA, Crooks JL, Czuczman GJ, Knight V. Ultrasound-Guided Injections of HYADD4 for Knee Osteoarthritis Improves Pain and Functional Outcomes at 3, 6, and 12 Months without Changes in Measured Synovial Fluid, Serum Collagen Biomarkers, or Most Synovial Fluid Biomarker Proteins at 3 Months. Journal of Clinical Medicine. 12. PMID 37685608 DOI: 10.3390/jcm12175541 |
0.503 |
|
2021 |
Meehan RT, Regan EA, Hoffman ED, Wolf ML, Gill MT, Crooks JL, Parmar PJ, Scheuring RA, Hill JC, Pacheco KA, Knight V. Synovial Fluid Cytokines, Chemokines and MMP Levels in Osteoarthritis Patients with Knee Pain Display a Profile Similar to Many Rheumatoid Arthritis Patients. Journal of Clinical Medicine. 10. PMID 34768546 DOI: 10.3390/jcm10215027 |
0.518 |
|
2021 |
Meehan RT, Amigues IA, Knight V. Precision Medicine for Rheumatoid Arthritis: The Right Drug for the Right Patient-Companion Diagnostics. Diagnostics (Basel, Switzerland). 11. PMID 34441297 DOI: 10.3390/diagnostics11081362 |
0.525 |
|
2021 |
Sadiku P, Willson JA, Ryan EM, Sammut D, Coelho P, Watts ER, Grecian R, Young JM, Bewley M, Arienti S, Mirchandani AS, Sanchez Garcia MA, Morrison T, Zhang A, Reyes L, ... ... Meehan RR, et al. Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis. Cell Metabolism. 33: 1062-1064. PMID 33951466 DOI: 10.1016/j.cmet.2021.03.018 |
0.484 |
|
2021 |
Sinton MC, Meseguer-Ripolles J, Lucendo-Villarin B, Wernig-Zorc S, Thomson JP, Carter RN, Lyall MJ, Walker PD, Thakker A, Meehan RR, Lavery GG, Morton NM, Ludwig C, Tennant DA, Hay DC, et al. A human pluripotent stem cell model for the analysis of metabolic dysfunction in hepatic steatosis. Iscience. 24: 101931. PMID 33409477 DOI: 10.1016/j.isci.2020.101931 |
0.539 |
|
2021 |
Zell-Baran LM, Krefft SD, Moore CM, Wolff J, Meehan R, Rose CS. Multiple breath washout test data for healthy controls. Data in Brief. 34: 106641. PMID 33365370 DOI: 10.1016/j.dib.2020.106641 |
0.507 |
|
2020 |
Zell-Baran LM, Krefft SD, Moore CM, Wolff J, Meehan R, Rose CS. Multiple breath washout: A noninvasive tool for identifying lung disease in symptomatic military deployers. Respiratory Medicine. 176: 106281. PMID 33340829 DOI: 10.1016/j.rmed.2020.106281 |
0.541 |
|
2020 |
Sadiku P, Willson JA, Ryan EM, Sammut D, Coelho P, Watts ER, Grecian R, Young JM, Bewley M, Arienti S, Mirchandani AS, Sanchez Garcia MA, Morrison T, Zhang A, Reyes L, ... ... Meehan RR, et al. Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis. Cell Metabolism. PMID 33306983 DOI: 10.1016/j.cmet.2020.11.016 |
0.525 |
|
2020 |
Lee AS, Scofield RH, Hammitt KM, Gupta N, Thomas DE, Moua T, Ussavarungsi K, St Clair EW, Meehan R, Dunleavy K, Makara M, Carsons SE, Carteron NL. Consensus Guidelines for Evaluation and Management of Pulmonary Disease in Sjögren's. Chest. PMID 33075377 DOI: 10.1016/j.chest.2020.10.011 |
0.528 |
|
2020 |
Shukla R, Mjoseng HK, Thomson JP, Kling S, Sproul D, Dunican DS, Ramsahoye B, Wongtawan T, Treindl F, Templin MF, Adams IR, Pennings S, Meehan RR. Activation of transcription factor circuity in 2i-induced ground state pluripotency is independent of repressive global epigenetic landscapes. Nucleic Acids Research. PMID 32585002 DOI: 10.1093/nar/gkaa529 |
0.629 |
|
2020 |
Dunican DS, Mjoseng HK, Duthie L, Flyamer IM, Bickmore WA, Meehan RR. Bivalent promoter hypermethylation in cancer is linked to the H327me3/H3K4me3 ratio in embryonic stem cells. Bmc Biology. 18: 25. PMID 32131813 DOI: 10.1186/s12915-020-0752-3 |
0.633 |
|
2020 |
Krefft SD, Wolff J, Zell-Baran L, Strand M, Gottschall EB, Meehan R, Rose CS. Respiratory Diseases in Post-9/11 Military Personnel Following Southwest Asia Deployment. Journal of Occupational and Environmental Medicine. PMID 31977922 DOI: 10.1097/Jom.0000000000001817 |
0.527 |
|
2019 |
McLaughlin K, Flyamer IM, Thomson JP, Mjoseng HK, Shukla R, Williamson I, Grimes GR, Illingworth RS, Adams IR, Pennings S, Meehan RR, Bickmore WA. DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency. Cell Reports. 29: 1974-1985.e6. PMID 31722211 DOI: 10.1016/j.celrep.2019.10.031 |
0.606 |
|
2019 |
Stancheva I, Hensey C, Meehan RR. Loss of the maintenance methyltransferase, xDnmt1, induces apoptosis in Xenopus embryos. The Embo Journal. 38: e103221. PMID 31612522 DOI: 10.15252/embj.2019103221 |
0.515 |
|
2019 |
Lyall MJ, Thomson JP, Cartier J, Ottaviano R, Kendall TJ, Meehan RR, Drake AJ. Non-alcoholic fatty liver disease (NAFLD) is associated with dynamic changes in DNA hydroxymethylation. Epigenetics. 1-11. PMID 31389294 DOI: 10.1080/15592294.2019.1649527 |
0.574 |
|
2019 |
Meehan R, Wilson C, Hoffman E, Altimier L, Kaessner M, Regan EA. Ultrasound measurement of knee synovial fluid during external pneumatic compression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 30644131 DOI: 10.1002/jor.24216 |
0.501 |
|
2018 |
Zell-Baran LM, Meehan R, Wolff J, Strand M, Krefft SD, Gottschall EB, Macedonia TV, Gross JE, Sanders OL, Pepper GC, Rose CS. Military Occupational Specialty Codes: Utility In Predicting Inhalation Exposures In Post-9/11 Deployers. Journal of Occupational and Environmental Medicine. PMID 31592941 DOI: 10.1097/Jom.0000000000001731 |
0.5 |
|
2018 |
Ford MJ, Yeyati PL, Mali GR, Keighren MA, Waddell SH, Mjoseng HK, Douglas AT, Hall EA, Sakaue-Sawano A, Miyawaki A, Meehan RR, Boulter L, Jackson IJ, Mill P, Mort RL. A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice. Developmental Cell. 47: 509-523.e5. PMID 30458140 DOI: 10.1016/j.devcel.2018.10.027 |
0.527 |
|
2018 |
Lentini A, Lagerwall C, Vikingsson S, Mjoseng HK, Douvlataniotis K, Vogt H, Green H, Meehan RR, Benson M, Nestor CE. A reassessment of DNA-immunoprecipitation-based genomic profiling. Nature Methods. PMID 29941872 DOI: 10.1038/s41592-018-0038-7 |
0.62 |
|
2018 |
Lyall MJ, Cartier J, Thomson JP, Cameron K, Meseguer-Ripolles J, O'Duibhir E, Szkolnicka D, Villarin BL, Wang Y, Blanco GR, Dunn WB, Meehan RR, Hay DC, Drake AJ. Modelling non-alcoholic fatty liver disease in human hepatocyte-like cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 373. PMID 29786565 DOI: 10.1098/rstb.2017.0362 |
0.587 |
|
2018 |
Cartier J, Smith T, Thomson JP, Rose CM, Khulan B, Heger A, Meehan RR, Drake AJ. Investigation into the role of the germline epigenome in the transmission of glucocorticoid-programmed effects across generations. Genome Biology. 19: 50. PMID 29636086 DOI: 10.1186/s13059-018-1422-4 |
0.56 |
|
2018 |
Raven A, Lu WY, Man TY, Ferreira-Gonzalez S, O'Duibhir E, Dwyer BJ, Thomson JP, Meehan RR, Bogorad R, Koteliansky V, Kotelevtsev Y, Ffrench-Constant C, Boulter L, Forbes SJ. Corrigendum: Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration. Nature. 555: 402. PMID 29542689 DOI: 10.1038/nature25996 |
0.515 |
|
2018 |
Meehan RR, Thomson JP, Lentini A, Nestor CE, Pennings S. DNA methylation as a genomic marker of exposure to chemical and environmental agents. Current Opinion in Chemical Biology. 45: 48-56. PMID 29505975 DOI: 10.1016/j.cbpa.2018.02.006 |
0.598 |
|
2018 |
Thomson JP, Meehan RR. Affinity-Based Enrichment Techniques for the Genome-Wide Analysis of 5-Hydroxymethylcytosine. Methods in Molecular Biology (Clifton, N.J.). 1708: 679-696. PMID 29224170 DOI: 10.1007/978-1-4939-7481-8_35 |
0.596 |
|
2017 |
Lyall MJ, Cartier J, Richards JA, Cobice D, Thomson JP, Meehan RR, Anderton SM, Drake AJ. Methyl donor deficient diets cause distinct alterations in lipid metabolism but are poorly representative of human NAFLD. Wellcome Open Research. 2: 67. PMID 29707653 DOI: 10.12688/wellcomeopenres.12199.1 |
0.579 |
|
2017 |
Meehan RR, Pennings S. Shoring up DNA methylation and H3K27me3 domain demarcation at developmental genes. The Embo Journal. PMID 29167195 DOI: 10.15252/embj.201798498 |
0.613 |
|
2017 |
Thomson JP, Ottaviano R, Buesen R, Moggs JG, Schwarz M, Meehan RR. Defining baseline epigenetic landscapes in the rat liver. Epigenomics. PMID 29130343 DOI: 10.2217/epi-2017-0029 |
0.591 |
|
2017 |
Buesen R, Chorley BN, da Silva Lima B, Daston G, Deferme L, Ebbels T, Gant TW, Goetz A, Greally J, Gribaldo L, Hackermüller J, Hubesch B, Jennen D, Johnson K, Kanno J, ... ... Meehan R, et al. Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop. Regulatory Toxicology and Pharmacology : Rtp. PMID 28958911 DOI: 10.1016/J.Yrtph.2017.09.002 |
0.537 |
|
2017 |
MacLennan M, García-Cañadas M, Reichmann J, Khazina E, Wagner G, Playfoot CJ, Salvador-Palomeque C, Mann AR, Peressini P, Sanchez L, Dobie K, Read D, Hung CC, Eskeland R, Meehan RR, et al. Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells. Elife. 6. PMID 28806172 DOI: 10.7554/eLife.26152 |
0.547 |
|
2017 |
Raven A, Lu WY, Man TY, Ferreira-Gonzalez S, O'Duibhir E, Dwyer BJ, Thomson JP, Meehan RR, Bogorad R, Koteliansky V, Kotelevtsev Y, Ffrench-Constant C, Boulter L, Forbes SJ. Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration. Nature. PMID 28700576 DOI: 10.1038/nature23015 |
0.521 |
|
2017 |
Krefft SD, Strand M, Smith J, Stroup C, Meehan R, Rose C. Utility of Lung Clearance Index Testing as a Noninvasive Marker of Deployment-related Lung Disease. Journal of Occupational and Environmental Medicine. PMID 28665837 DOI: 10.1097/Jom.0000000000001058 |
0.523 |
|
2017 |
Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, ... ... Meehan RR, et al. Corrigendum: SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nature Genetics. 49: 969. PMID 28546579 DOI: 10.1038/ng0617-969c |
0.495 |
|
2017 |
Cole JJ, Robertson NA, Rather MI, Thomson JP, McBryan T, Sproul D, Wang T, Brock C, Clark W, Ideker T, Meehan RR, Miller RA, Brown-Borg HM, Adams PD. Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions. Genome Biology. 18: 58. PMID 28351383 DOI: 10.1186/S13059-017-1185-3 |
0.594 |
|
2017 |
Vafadar-Isfahani N, Parr C, McMillan LE, Sanner J, Yeo Z, Saddington S, Peacock O, Cruickshanks HA, Meehan RR, Lund JN, Tufarelli C. Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer. Epigenetics. 0. PMID 28300471 DOI: 10.1080/15592294.2017.1300729 |
0.622 |
|
2017 |
Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, ... ... Meehan RR, et al. SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nature Genetics. PMID 28067909 DOI: 10.1038/Ng.3743 |
0.546 |
|
2016 |
Thomson JP, Meehan RR. The application of genome-wide 5-hydroxymethylcytosine studies in cancer research. Epigenomics. PMID 27936926 DOI: 10.2217/epi-2016-0122 |
0.575 |
|
2016 |
Tashkin DP, Roth MD, Clements PJ, Furst DE, Khanna D, Kleerup EC, Goldin J, Arriola E, Volkmann ER, Kafaja S, Silver R, Steen V, Strange C, Wise R, Wigley F, ... ... Meehan R, et al. Mycophenolate mofetil versus oral cyclophosphamide in scleroderma-related interstitial lung disease (SLS II): a randomised controlled, double-blind, parallel group trial. The Lancet. Respiratory Medicine. PMID 27469583 DOI: 10.1016/S2213-2600(16)30152-7 |
0.524 |
|
2016 |
Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR. A Mutant Form of MeCP2 Protein Associated with Human Rett Syndrome Cannot Be Displaced from Methylated DNA by Notch in Xenopus Embryos. Molecular Cell. 63: 179. PMID 27392147 DOI: 10.1016/j.molcel.2016.06.007 |
0.604 |
|
2016 |
Nestor CE, Lentini A, Hägg Nilsson C, Gawel DR, Gustafsson M, Mattson L, Wang H, Rundquist O, Meehan RR, Klocke B, Seifert M, Hauck SM, Laumen H, Zhang H, Benson M. 5-Hydroxymethylcytosine Remodeling Precedes Lineage Specification during Differentiation of Human CD4(+) T Cells. Cell Reports. PMID 27346350 DOI: 10.1016/j.celrep.2016.05.091 |
0.592 |
|
2016 |
Thomson JP, Ottaviano R, Unterberger EB, Lempiäinen H, Muller A, Terranova R, Illingworth RS, Webb S, Kerr AR, Lyall MJ, Drake AJ, Wolf CR, Moggs JG, Schwarz M, Meehan RR. Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer. Cancer Research. 76: 3097-3108. PMID 27197233 DOI: 10.1158/0008-5472.CAN-15-1910 |
0.616 |
|
2015 |
Dunican DS, Pennings S, Meehan RR. Lsh Is Essential for Maintaining Global DNA Methylation Levels in Amphibia and Fish and Interacts Directly with Dnmt1. Biomed Research International. 2015: 740637. PMID 26491684 DOI: 10.1155/2015/740637 |
0.648 |
|
2015 |
Miousse IR, Currie R, Datta K, Ellinger-Ziegelbauer H, French JE, Harrill AH, Koturbash I, Lawton M, Mann D, Meehan RR, Moggs JG, O'Lone R, Rasoulpour RJ, Pera RA, Thompson K. Importance of investigating epigenetic alterations for industry and regulators: an appraisal of current efforts by the Health and Environmental Sciences Institute. Toxicology. PMID 26134581 DOI: 10.1016/J.Tox.2015.06.009 |
0.578 |
|
2015 |
Thomson JP, Nestor CE, Meehan RR. 5-Hydroxymethylcytosine Profiling in Human DNA. Methods in Molecular Biology (Clifton, N.J.). PMID 26126447 DOI: 10.1007/7651_2015_268 |
0.598 |
|
2015 |
Thomson JP, Fawkes A, Ottaviano R, Hunter JM, Shukla R, Mjoseng HK, Clark R, Coutts A, Murphy L, Meehan RR. DNA immunoprecipitation semiconductor sequencing (DIP-SC-seq) as a rapid method to generate genome wide epigenetic signatures. Scientific Reports. 5: 9778. PMID 25985418 DOI: 10.1038/srep09778 |
0.594 |
|
2015 |
Nestor CE, Ottaviano R, Reinhardt D, Cruickshanks HA, Mjoseng HK, McPherson RC, Lentini A, Thomson JP, Dunican DS, Pennings S, Anderton SM, Benson M, Meehan RR. Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems. Genome Biology. 16: 11. PMID 25648825 DOI: 10.1186/s13059-014-0576-y |
0.615 |
|
2015 |
Krefft SD, Meehan R, Rose CS. Emerging spectrum of deployment-related respiratory diseases Current Opinion in Pulmonary Medicine. 21: 185-192. PMID 25575366 DOI: 10.1097/MCP.0000000000000143 |
0.534 |
|
2015 |
Meng H, Harrison DJ, Meehan RR. MBD4 interacts with and recruits USP7 to heterochromatic foci. Journal of Cellular Biochemistry. 116: 476-85. PMID 25358258 DOI: 10.1002/Jcb.25001 |
0.619 |
|
2014 |
McPherson RC, Konkel JE, Prendergast CT, Thomson JP, Ottaviano R, Leech MD, Kay O, Zandee SE, Sweenie CH, Wraith DC, Meehan RR, Drake AJ, Anderton SM. Epigenetic modification of the PD-1 (Pdcd1) promoter in effector CD4(+) T cells tolerized by peptide immunotherapy. Elife. 3. PMID 25546306 DOI: 10.7554/eLife.03416 |
0.559 |
|
2014 |
Gustafsson M, Nestor CE, Zhang H, Barabási AL, Baranzini S, Brunak S, Chung KF, Federoff HJ, Gavin AC, Meehan RR, Picotti P, Pujana MÀ, Rajewsky N, Smith KG, Sterk PJ, et al. Modules, networks and systems medicine for understanding disease and aiding diagnosis. Genome Medicine. 6: 82. PMID 25473422 DOI: 10.1186/S13073-014-0082-6 |
0.557 |
|
2014 |
Rose CM, van den Driesche S, Sharpe RM, Meehan RR, Drake AJ. Dynamic changes in DNA modification states during late gestation male germ line development in the rat. Epigenetics & Chromatin. 7: 19. PMID 25225576 DOI: 10.1186/1756-8935-7-19 |
0.61 |
|
2014 |
Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, ... ... Meehan RR, et al. Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 139: 501-11. PMID 24690595 DOI: 10.1093/toxsci/kfu038 |
0.534 |
|
2014 |
Nestor CE, Meehan RR. Hydroxymethylated DNA immunoprecipitation (hmeDIP). Methods in Molecular Biology (Clifton, N.J.). 1094: 259-67. PMID 24162994 DOI: 10.1007/978-1-62703-706-8_20 |
0.625 |
|
2014 |
Nestor CE, Reddington JP, Benson M, Meehan RR. Investigating 5-hydroxymethylcytosine (5hmC): the state of the art. Methods in Molecular Biology (Clifton, N.J.). 1094: 243-58. PMID 24162993 DOI: 10.1007/978-1-62703-706-8_19 |
0.546 |
|
2014 |
Crichton JH, Dunican DS, Maclennan M, Meehan RR, Adams IR. Defending the genome from the enemy within: mechanisms of retrotransposon suppression in the mouse germline. Cellular and Molecular Life Sciences : Cmls. 71: 1581-605. PMID 24045705 DOI: 10.1007/s00018-013-1468-0 |
0.541 |
|
2013 |
Dunican DS, Cruickshanks HA, Suzuki M, Semple CA, Davey T, Arceci RJ, Greally J, Adams IR, Meehan RR. Lsh regulates LTR retrotransposon repression independently of Dnmt3b function. Genome Biology. 14: R146. PMID 24367978 DOI: 10.1186/Gb-2013-14-12-R146 |
0.647 |
|
2013 |
Laird A, Thomson JP, Harrison DJ, Meehan RR. 5-hydroxymethylcytosine profiling as an indicator of cellular state. Epigenomics. 5: 655-69. PMID 24283880 DOI: 10.2217/epi.13.69 |
0.618 |
|
2013 |
Reddington JP, Sproul D, Meehan RR. DNA methylation reprogramming in cancer: does it act by re-configuring the binding landscape of Polycomb repressive complexes? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 36: 134-40. PMID 24277643 DOI: 10.1002/bies.201300130 |
0.652 |
|
2013 |
Cruickshanks HA, McBryan T, Nelson DM, Vanderkraats ND, Shah PP, van Tuyn J, Singh Rai T, Brock C, Donahue G, Dunican DS, Drotar ME, Meehan RR, Edwards JR, Berger SL, Adams PD. Senescent cells harbour features of the cancer epigenome. Nature Cell Biology. 15: 1495-506. PMID 24270890 DOI: 10.1038/Ncb2879 |
0.64 |
|
2013 |
Tufarelli C, Cruickshanks HA, Meehan RR. LINE-1 activation and epigenetic silencing of suppressor genes in cancer: Causally related events? Mobile Genetic Elements. 3: e26832. PMID 24251074 DOI: 10.4161/mge.26832 |
0.59 |
|
2013 |
Thomson JP, Hunter JM, Nestor CE, Dunican DS, Terranova R, Moggs JG, Meehan RR. Comparative analysis of affinity-based 5-hydroxymethylation enrichment techniques. Nucleic Acids Research. 41: e206. PMID 24214958 DOI: 10.1093/nar/gkt1080 |
0.601 |
|
2013 |
Thomson JP, Moggs JG, Wolf CR, Meehan RR. Epigenetic profiles as defined signatures of xenobiotic exposure. Mutation Research. Genetic Toxicology and Environmental Mutagenesis. 3-9. PMID 24001620 DOI: 10.1016/j.mrgentox.2013.08.007 |
0.61 |
|
2013 |
Thomson JP, Hunter JM, Meehan RR. Deep C diving: mapping the low-abundance modifications of the DNA demethylation pathway. Genome Biology. 14: 118. PMID 23732041 DOI: 10.1186/gb-2013-14-5-118 |
0.567 |
|
2013 |
Adams IR, Meehan RR. From paramutation to paradigm. Plos Genetics. 9: e1003537. PMID 23717216 DOI: 10.1371/journal.pgen.1003537 |
0.481 |
|
2013 |
Dunican DS, Pennings S, Meehan RR. The CXXC-TET bridge--mind the methylation gap! Cell Research. 23: 973-4. PMID 23711677 DOI: 10.1038/cr.2013.71 |
0.6 |
|
2013 |
Cruickshanks HA, Vafadar-Isfahani N, Dunican DS, Lee A, Sproul D, Lund JN, Meehan RR, Tufarelli C. Expression of a large LINE-1-driven antisense RNA is linked to epigenetic silencing of the metastasis suppressor gene TFPI-2 in cancer. Nucleic Acids Research. 41: 6857-69. PMID 23703216 DOI: 10.1093/nar/gkt438 |
0.573 |
|
2013 |
Rose CM, van den Driesche S, Meehan RR, Drake AJ. Epigenetic reprogramming: preparing the epigenome for the next generation. Biochemical Society Transactions. 41: 809-14. PMID 23697942 DOI: 10.1042/BST20120356 |
0.642 |
|
2013 |
Thomson JP, Hunter JM, Lempiäinen H, Müller A, Terranova R, Moggs JG, Meehan RR. Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver. Nucleic Acids Research. 41: 5639-54. PMID 23598998 DOI: 10.1093/nar/gkt232 |
0.606 |
|
2013 |
Fernández Pérez ER, Krishnamoorthy M, Brown KK, Huie TJ, Fischer A, Solomon JJ, Meehan RT, Olson AL, Achcar RD, Swigris JJ. FEV1 over time in patients with connective tissue disease-related bronchiolitis Respiratory Medicine. 107: 883-889. PMID 23582575 DOI: 10.1016/j.rmed.2013.02.019 |
0.528 |
|
2013 |
Reddington JP, Perricone SM, Nestor CE, Reichmann J, Youngson NA, Suzuki M, Reinhardt D, Dunican DS, Prendergast JG, Mjoseng H, Ramsahoye BH, Whitelaw E, Greally JM, Adams IR, Bickmore WA, ... Meehan RR, et al. Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes. Genome Biology. 14: R25. PMID 23531360 DOI: 10.1186/Gb-2013-14-3-R25 |
0.639 |
|
2013 |
Reddington JP, Pennings S, Meehan RR. Non-canonical functions of the DNA methylome in gene regulation. The Biochemical Journal. 451: 13-23. PMID 23489368 DOI: 10.1042/BJ20121585 |
0.655 |
|
2013 |
Fischer A, Brown KK, Du Bois RM, Frankel SK, Cosgrove GP, Fernandez-Perez ER, Huie TJ, Krishnamoorthy M, Meehan RT, Olson AL, Solomon JJ, Swigris JJ. Mycophenolate mofetil improves lung function in connective tissue disease-associated interstitial lung disease Journal of Rheumatology. 40: 640-646. PMID 23457378 DOI: 10.3899/jrheum.121043 |
0.548 |
|
2013 |
Reichmann J, Reddington JP, Best D, Read D, Öllinger R, Meehan RR, Adams IR. The genome-defence gene tex19.1 suppresses line-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice Human Molecular Genetics. 22: 1791-1806. PMID 23364048 DOI: 10.1093/hmg/ddt029 |
0.62 |
|
2013 |
Sproul D, Meehan RR. Genomic insights into cancer-associated aberrant CpG island hypermethylation. Briefings in Functional Genomics. 12: 174-90. PMID 23341493 DOI: 10.1093/bfgp/els063 |
0.623 |
|
2013 |
Lempiäinen H, Couttet P, Bolognani F, Müller A, Dubost V, Luisier R, Del Rio Espinola A, Vitry V, Unterberger EB, Thomson JP, Treindl F, Metzger U, Wrzodek C, Hahne F, Zollinger T, ... ... Meehan RR, et al. Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion. Toxicological Sciences : An Official Journal of the Society of Toxicology. 131: 375-86. PMID 23091169 DOI: 10.1093/Toxsci/Kfs303 |
0.567 |
|
2012 |
Thomson JP, Lempiäinen H, Hackett JA, Nestor CE, Müller A, Bolognani F, Oakeley EJ, Schübeler D, Terranova R, Reinhardt D, Moggs JG, Meehan RR. Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome. Genome Biology. 13: R93. PMID 23034186 DOI: 10.1186/gb-2012-13-10-r93 |
0.634 |
|
2012 |
Sproul D, Kitchen RR, Nestor CE, Dixon JM, Sims AH, Harrison DJ, Ramsahoye BH, Meehan RR. Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns. Genome Biology. 13: R84. PMID 23034185 DOI: 10.1186/gb-2012-13-10-r84 |
0.593 |
|
2012 |
Hackett JA, Reddington JP, Nestor CE, Dunican DS, Branco MR, Reichmann J, Reik W, Surani MA, Adams IR, Meehan RR. Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline. Development (Cambridge, England). 139: 3623-32. PMID 22949617 DOI: 10.1242/dev.081661 |
0.63 |
|
2012 |
Katz E, Sims AH, Sproul D, Caldwell H, Dixon MJ, Meehan RR, Harrison DJ. Targeting of Rac GTPases blocks the spread of intact human breast cancer. Oncotarget. 3: 608-19. PMID 22689141 |
0.525 |
|
2012 |
Drake AJ, McPherson RC, Godfrey KM, Cooper C, Lillycrop KA, Hanson MA, Meehan RR, Seckl JR, Reynolds RM. An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth. Clinical Endocrinology. 77: 808-15. PMID 22642564 DOI: 10.1111/J.1365-2265.2012.04453.X |
0.556 |
|
2012 |
Rose C, Abraham J, Harkins D, Miller R, Morris M, Zacher L, Meehan R, Szema A, Tolle J, King M, Jackson D, Lewis J, Stahl A, Lyles MB, Hodgson M, et al. Overview and recommendations for medical screening and diagnostic evaluation for postdeployment lung disease in returning US warfighters. Journal of Occupational and Environmental Medicine / American College of Occupational and Environmental Medicine. 54: 746-51. PMID 22588477 DOI: 10.1097/JOM.0b013e31825297ba |
0.523 |
|
2012 |
Reichmann J, Crichton JH, Madej MJ, Taggart M, Gautier P, Garcia-Perez JL, Meehan RR, Adams IR. Microarray analysis of LTR retrotransposon silencing identifies Hdac1 as a regulator of retrotransposon expression in mouse embryonic stem cells. Plos Computational Biology. 8: e1002486. PMID 22570599 DOI: 10.1371/journal.pcbi.1002486 |
0.6 |
|
2012 |
Coates A, Meehan R, Milla C. Dyspnea in a patient with Raynaud's phenomenon: the uncovering of interstitial lung disease. Pediatric Pulmonology. 47: 926-7. PMID 22467473 DOI: 10.1002/Ppul.22549 |
0.549 |
|
2012 |
Nestor CE, Ottaviano R, Reddington J, Sproul D, Reinhardt D, Dunican D, Katz E, Dixon JM, Harrison DJ, Meehan RR. Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes. Genome Research. 22: 467-77. PMID 22106369 DOI: 10.1101/gr.126417.111 |
0.562 |
|
2011 |
Meng HX, Hackett JA, Nestor C, Dunican DS, Madej M, Reddington JP, Pennings S, Harrison DJ, Meehan RR. Apoptosis and DNA methylation. Cancers. 3: 1798-820. PMID 24212783 DOI: 10.3390/cancers3021798 |
0.647 |
|
2011 |
Drake AJ, Liu L, Kerrigan D, Meehan RR, Seckl JR. Multigenerational programming in the glucocorticoid programmed rat is associated with generation-specific and parent of origin effects Epigenetics. 6: 1334-1343. PMID 22086116 DOI: 10.4161/epi.6.11.17942 |
0.562 |
|
2011 |
Loughery JE, Dunne PD, O'Neill KM, Meehan RR, McDaid JR, Walsh CP. DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response. Human Molecular Genetics. 20: 3241-55. PMID 21636528 DOI: 10.1093/hmg/ddr236 |
0.615 |
|
2011 |
Reddington JP, Meehan RR. Putting muscle in DNA methylation. Cell Research. 21: 1531-3. PMID 21625268 DOI: 10.1038/cr.2011.91 |
0.586 |
|
2011 |
Rubtsov AV, Rubtsova K, Fischer A, Meehan RT, Gillis JZ, Kappler JW, Marrack P. Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c⁺ B-cell population is important for the development of autoimmunity. Blood. 118: 1305-15. PMID 21543762 DOI: 10.1182/Blood-2011-01-331462 |
0.531 |
|
2011 |
Sproul D, Nestor C, Culley J, Dickson JH, Dixon JM, Harrison DJ, Meehan RR, Sims AH, Ramsahoye BH. Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 108: 4364-9. PMID 21368160 DOI: 10.1073/pnas.1013224108 |
0.558 |
|
2011 |
Katz E, Dubois-Marshall S, Sims AH, Gautier P, Caldwell H, Meehan RR, Harrison DJ. An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer. Plos One. 6: e17083. PMID 21347235 DOI: 10.1371/journal.pone.0017083 |
0.543 |
|
2010 |
Whitelaw NC, Chong S, Morgan DK, Nestor C, Bruxner TJ, Ashe A, Lambley E, Meehan R, Whitelaw E. Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise. Genome Biology. 11: R111. PMID 21092094 DOI: 10.1186/gb-2010-11-11-r111 |
0.562 |
|
2010 |
Nestor C, Ruzov A, Meehan R, Dunican D. Enzymatic approaches and bisulfite sequencing cannot distinguish between 5-methylcytosine and 5-hydroxymethylcytosine in DNA. Biotechniques. 48: 317-9. PMID 20569209 DOI: 10.2144/000113403 |
0.619 |
|
2009 |
Ruzov A, Shorning B, Mortusewicz O, Dunican DS, Leonhardt H, Meehan RR. MBD4 and MLH1 are required for apoptotic induction in xDNMT1-depleted embryos. Development (Cambridge, England). 136: 2277-86. PMID 19502488 DOI: 10.1242/dev.032227 |
0.586 |
|
2009 |
Fischer A, Swigris JJ, du Bois RM, Groshong SD, Cool CD, Sahin H, Lynch DA, Gillis JZ, Cohen MD, Meehan RT, Brown KK. Minor salivary gland biopsy to detect primary Sjogren syndrome in patients with interstitial lung disease. Chest. 136: 1072-8. PMID 19429722 DOI: 10.1378/chest.08-2839 |
0.535 |
|
2009 |
Gizinski AM, Mascolo M, Loucks JL, Kervitsky A, Meehan RT, Brown KK, Holers VM, Deane KD. Rheumatoid arthritis (RA)-specific autoantibodies in patients with interstitial lung disease and absence of clinically apparent articular RA. Clinical Rheumatology. 28: 611-3. PMID 19252818 DOI: 10.1007/S10067-009-1128-9 |
0.518 |
|
2009 |
Ruzov A, Savitskaya E, Hackett JA, Reddington JP, Prokhortchouk A, Madej MJ, Chekanov N, Li M, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR. The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development. Development (Cambridge, England). 136: 729-38. PMID 19158185 DOI: 10.1242/dev.025569 |
0.609 |
|
2009 |
Ruzov A, Hackett JA, Prokhortchouk A, Reddington JP, Madej MJ, Dunican DS, Prokhortchouk E, Pennings S, Meehan RR. The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways. Development (Cambridge, England). 136: 723-7. PMID 19158184 DOI: 10.1242/dev.025577 |
0.517 |
|
2009 |
Taylor J, Moore H, Beaujean N, Gardner J, Wilmut I, Meehan R, Young L. Cloning and expression of sheep DNA methyltransferase 1 and its development-specific isoform. Molecular Reproduction and Development. 76: 501-13. PMID 18951375 DOI: 10.1002/Mrd.20968 |
0.606 |
|
2008 |
Fischer A, Swigris JJ, Groshong SD, Cool CD, Sahin H, Lynch DA, Curran-Everett D, Gillis JZ, Meehan RT, Brown KK. Clinically significant interstitial lung disease in limited scleroderma: histopathology, clinical features, and survival. Chest. 134: 601-605. PMID 18403656 DOI: 10.1378/chest.08-0053 |
0.523 |
|
2008 |
Dunican DS, Ruzov A, Hackett JA, Meehan RR. xDnmt1 regulates transcriptional silencing in pre-MBT Xenopus embryos independently of its catalytic function. Development (Cambridge, England). 135: 1295-302. PMID 18305009 DOI: 10.1242/dev.016402 |
0.548 |
|
2008 |
Swigris JJ, Fischer A, Gilles J, Meehan RT, Brown KK. Pulmonary and thrombotic manifestations of systemic lupus erythematosus Chest. 133: 271-280. PMID 18187752 DOI: 10.1378/chest.07-0079 |
0.543 |
|
2007 |
Fischer A, Misumi S, Curran-Everett D, Meehan RT, Ulrich SK, Swigris JJ, Frankel SK, Cosgrove GP, Lynch DA, Brown KK. Pericardial abnormalities predict the presence of echocardiographically defined pulmonary arterial hypertension in systemic sclerosis-related interstitial lung disease. Chest. 131: 988-92. PMID 17426200 DOI: 10.1378/chest.06-2317 |
0.53 |
|
2007 |
Fischer A, Meehan R, Brown K, Feghali-Bostwick C, West S. Reflux and autoimmunity: common links among patients with pulmonary fibrosis? Chest. 131: 940-941. PMID 17356120 DOI: 10.1016/S0012-3692(15)38926-1 |
0.518 |
|
2006 |
Fischer A, Meehan RT, Feghali-Bostwick CA, West SG, Brown KK. Unique characteristics of systemic sclerosis sine scleroderma-associated interstitial lung disease Chest. 130: 976-981. PMID 17035427 DOI: 10.1378/chest.130.4.976 |
0.53 |
|
2006 |
Swigris JJ, Olson AL, Fischer A, Lynch DA, Cosgrove GP, Frankel SK, Meehan RT, Brown KK. Mycophenolate mofetil is safe, well tolerated, and preserves lung function in patients with connective tissue disease-related interstitial lung disease Chest. 130: 30-36. PMID 16840379 DOI: 10.1378/chest.130.1.30 |
0.541 |
|
2006 |
Moore HR, Meehan RR, Young LE. Methylation-sensitive polymerase chain reaction. Methods in Molecular Biology (Clifton, N.J.). 325: 239-49. PMID 16761730 DOI: 10.1385/1-59745-005-7:239 |
0.602 |
|
2006 |
Frankel SK, Cosgrove GP, Fischer A, Meehan RT, Brown KK. Update in the diagnosis and management of pulmonary vasculitis. Chest. 129: 452-65. PMID 16478866 DOI: 10.1378/chest.129.2.452 |
0.538 |
|
2005 |
Meehan RR, Dunican DS, Ruzov A, Pennings S. Epigenetic silencing in embryogenesis. Experimental Cell Research. 309: 241-9. PMID 16112110 DOI: 10.1016/j.yexcr.2005.06.023 |
0.589 |
|
2004 |
Ruzov A, Dunican DS, Prokhortchouk A, Pennings S, Stancheva I, Prokhortchouk E, Meehan RR. Kaiso is a genome-wide repressor of transcription that is essential for amphibian development. Development (Cambridge, England). 131: 6185-94. PMID 15548582 DOI: 10.1242/dev.01549 |
0.641 |
|
2004 |
Davey CS, Pennings S, Reilly C, Meehan RR, Allan J. A determining influence for CpG dinucleotides on nucleosome positioning in vitro. Nucleic Acids Research. 32: 4322-31. PMID 15310836 DOI: 10.1093/nar/gkh749 |
0.616 |
|
2004 |
Tanaka N, Kim JS, Newell JD, Brown KK, Cool CD, Meehan R, Emoto T, Matsumoto T, Lynch DA. Rheumatoid arthritis-related lung diseases: CT findings. Radiology. 232: 81-91. PMID 15166329 DOI: 10.1148/radiol.2321030174 |
0.521 |
|
2004 |
Beaujean N, Taylor JE, McGarry M, Gardner JO, Wilmut I, Loi P, Ptak G, Galli C, Lazzari G, Bird A, Young LE, Meehan RR. The effect of interspecific oocytes on demethylation of sperm DNA. Proceedings of the National Academy of Sciences of the United States of America. 101: 7636-40. PMID 15136736 DOI: 10.1073/Pnas.0400730101 |
0.609 |
|
2004 |
Beaujean N, Hartshorne G, Cavilla J, Taylor J, Gardner J, Wilmut I, Meehan R, Young L. Non-conservation of mammalian preimplantation methylation dynamics. Current Biology : Cb. 14: R266-7. PMID 15062117 DOI: 10.1016/J.Cub.2004.03.019 |
0.569 |
|
2004 |
Beaujean N, Taylor J, Gardner J, Wilmut I, Meehan R, Young L. Effect of limited DNA methylation reprogramming in the normal sheep embryo on somatic cell nuclear transfer. Biology of Reproduction. 71: 185-93. PMID 14998909 DOI: 10.1095/Biolreprod.103.026559 |
0.632 |
|
2004 |
Ruzov AS, Mertsalov IB, Meehan R, Kiselev SL, Buchman VL, Korobko IV. Cloning and developmental expression of MARK/Par-1/MELK-related protein kinase xMAK-V in Xenopus laevis. Development Genes and Evolution. 214: 139-43. PMID 14740210 DOI: 10.1007/s00427-004-0381-9 |
0.522 |
|
2003 |
Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR. A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos. Molecular Cell. 12: 425-35. PMID 14536082 DOI: 10.1016/S1097-2765(03)00276-4 |
0.617 |
|
2003 |
Shorning BY, Wilson DB, Meehan RR, Ashley RH. Molecular cloning and developmental expression of two Chloride Intracellular Channel (CLIC) genes in Xenopus laevis. Development Genes and Evolution. 213: 514-8. PMID 13680226 DOI: 10.1007/S00427-003-0356-2 |
0.552 |
|
2003 |
Meehan RR, Kao CF, Pennings S. HP1 binding to native chromatin in vitro is determined by the hinge region and not by the chromodomain. The Embo Journal. 22: 3164-74. PMID 12805230 DOI: 10.1093/emboj/cdg306 |
0.587 |
|
2003 |
Meehan RR. DNA methylation in animal development. Seminars in Cell & Developmental Biology. 14: 53-65. PMID 12524008 DOI: 10.1016/s1084-9521(02)00137-4 |
0.646 |
|
2002 |
Stancheva I, El-Maarri O, Walter J, Niveleau A, Meehan RR. DNA methylation at promoter regions regulates the timing of gene activation in Xenopus laevis embryos. Developmental Biology. 243: 155-65. PMID 11846484 DOI: 10.1006/dbio.2001.0560 |
0.641 |
|
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