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Nicholas T. Hertz, Ph.D - Publications

Affiliations: 
2007-2013 Ph.D (Chemistry and Chemical Biology) University of California, San Francisco, San Francisco, CA 
 2013- Brain Development and Repair Rockefeller University, New York, NY, United States 
Area:
Chemical Biology, Neuroscience
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Dugan M, Ferguson L, Hertz N, Chalkley R, Burlingame A, Shokat K, Parker P, Messing R. Chemical Genetic Identification of Protein Kinase C Epsilon Substrates in Mouse Brain. Molecular & Cellular Proteomics : McP. 100522. PMID 36863607 DOI: 10.1016/j.mcpro.2023.100522  0.481
2019 Loonat AA, Martin ED, Sarafraz-Shekary N, Tilgner K, Hertz NT, Levin R, Shokat KM, Burlingame AL, Arabacilar P, Uddin S, Thomas M, Marber MS, Clark JE. p38γ MAPK contributes to left ventricular remodeling after pathologic stress and disinhibits calpain through phosphorylation of calpastatin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701545R. PMID 31638431 DOI: 10.1096/Fj.201701545R  0.713
2019 Hertz NT, Adams EL, Weber RA, Shen RJ, O'Rourke MK, Simon DJ, Zebroski H, Olsen O, Morgan CW, Mileur TR, Hitchcock AM, Sinnott Armstrong NA, Wainberg M, Bassik MC, Molina H, et al. Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration. Neuron. PMID 31221560 DOI: 10.1016/J.Neuron.2019.05.030  0.528
2019 Wang G, Simon DJ, Wu Z, Belsky DM, Heller E, O'Rourke MK, Hertz NT, Molina H, Zhong G, Tessier-Lavigne M, Zhuang X. Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration. Elife. 8. PMID 31042147 DOI: 10.7554/Elife.38730  0.529
2019 Wang G, Simon DJ, Wu Z, Belsky DM, Heller E, O'Rourke MK, Hertz NT, Molina H, Zhong G, Tessier-Lavigne M, Zhuang X. Author response: Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration Elife. DOI: 10.7554/Elife.38730.041  0.5
2018 Bowie LE, Maiuri T, Alpaugh M, Gabriel M, Arbez N, Galleguillos D, Hung CLK, Patel S, Xia J, Hertz NT, Ross CA, Litchfield DW, Sipione S, Truant R. N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987005 DOI: 10.1073/Pnas.1801772115  0.381
2018 Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, et al. CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity. Nature Genetics. PMID 29507424 DOI: 10.1038/S41588-018-0070-7  0.5
2017 Orr AL, Rutaganira FU, de Roulet D, Huang EJ, Hertz NT, Shokat KM, Nakamura K. Long-term oral kinetin does not protect against α-synuclein-induced neurodegeneration in rodent models of Parkinson's disease. Neurochemistry International. PMID 28434973 DOI: 10.1016/J.Neuint.2017.04.006  0.726
2016 Levin RS, Hertz NT, Burlingame AL, Shokat KM, Mukherjee S. Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen. Proceedings of the National Academy of Sciences of the United States of America. 113: E4776-83. PMID 27482120 DOI: 10.1073/Pnas.1608355113  0.762
2016 Simon DJ, Pitts J, Hertz NT, Yang J, Yamagishi Y, Olsen O, Tešić Mark M, Molina H, Tessier-Lavigne M. Axon Degeneration Gated by Retrograde Activation of Somatic Pro-apoptotic Signaling. Cell. 164: 1031-45. PMID 26898330 DOI: 10.1016/J.Cell.2016.01.032  0.714
2015 Schaffer BE, Levin RS, Hertz NT, Maures TJ, Schoof ML, Hollstein PE, Benayoun BA, Banko MR, Shaw RJ, Shokat KM, Brunet A. Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction. Cell Metabolism. 22: 907-21. PMID 26456332 DOI: 10.1016/J.Cmet.2015.09.009  0.75
2015 Friedel P, Kahle KT, Zhang J, Hertz N, Pisella LI, Buhler E, Schaller F, Duan J, Khanna AR, Bishop PN, Shokat KM, Medina I. WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons. Science Signaling. 8: ra65. PMID 26126716 DOI: 10.1126/Scisignal.Aaa0354  0.523
2014 Ultanir SK, Yadav S, Hertz NT, Oses-Prieto JA, Claxton S, Burlingame AL, Shokat KM, Jan LY, Jan YN. MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. Neuron. 84: 968-82. PMID 25456499 DOI: 10.1016/J.Neuron.2014.10.025  0.612
2014 Schroeder CM, Ostrem JM, Hertz NT, Vale RD. A Ras-like domain in the light intermediate chain bridges the dynein motor to a cargo-binding region. Elife. 3: e03351. PMID 25272277 DOI: 10.7554/Elife.03351  0.707
2014 Gustafson WC, Meyerowitz JG, Nekritz EA, Chen J, Benes C, Charron E, Simonds EF, Seeger R, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA. Drugging MYCN through an allosteric transition in Aurora kinase A. Cancer Cell. 26: 414-27. PMID 25175806 DOI: 10.1016/J.Ccr.2014.07.015  0.775
2014 Gustafson WC, Meyerowitz JG, Nekritz EA, Charron E, Matthay KK, Hertz NT, Eilers M, Shokat KM, Weiss WA. Abstract PR08: Drugging MYCN protein stability through an allosteric transition in Aurora kinase A Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-Pr08  0.78
2014 Gustafson WC, Meyerowitz JG, Nekritz EA, Charron EA, Chanthery Y, Simonds E, Matthay K, Hertz N, Shokat K, Weiss WA. Abstract 2688: Drugging MYCN through an allosteric transition in Aurora A kinase Cancer Research. 74: 2688-2688. DOI: 10.1158/1538-7445.Am2014-2688  0.775
2014 Loonat A, Hunt F, Choi SH, Martin ED, Hertz NT, Levin B, Shokat KM, Burlingame AL, Marber MS, Clark JE. ELUCIDATING THE ROLE OF P38γ IN PATHOLOGICAL CARDIAC HYPERTROPHY Heart. 100: A18.2-A18. DOI: 10.1136/heartjnl-2014-306916.54  0.348
2013 Hertz NT, Berthet A, Sos ML, Thorn KS, Burlingame AL, Nakamura K, Shokat KM. A neo-substrate that amplifies catalytic activity of parkinson's-disease-related kinase PINK1. Cell. 154: 737-47. PMID 23953109 DOI: 10.1016/J.Cell.2013.07.030  0.724
2012 Ultanir SK, Hertz NT, Li G, Ge WP, Burlingame AL, Pleasure SJ, Shokat KM, Jan LY, Jan YN. Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron. 73: 1127-42. PMID 22445341 DOI: 10.1016/J.Neuron.2012.01.019  0.695
2012 Hengeveld RC, Hertz NT, Vromans MJ, Zhang C, Burlingame AL, Shokat KM, Lens SM. Development of a chemical genetic approach for human aurora B kinase identifies novel substrates of the chromosomal passenger complex. Molecular & Cellular Proteomics : McP. 11: 47-59. PMID 22267324 DOI: 10.1074/Mcp.M111.013912  0.615
2011 Brennan DF, Dar AC, Hertz NT, Chao WC, Burlingame AL, Shokat KM, Barford D. A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK. Nature. 472: 366-9. PMID 21441910 DOI: 10.1038/Nature09860  0.773
2011 Brennan DF, Dar AC, Hertz NT, Chao W, Burlingame AL, Shokat KM, Barford D. A Raf-Induced Allosteric Transition of Ksr Stimulates Ksr and Raf Phosphorylation of Mek Nature. 472: 366. DOI: 10.2210/Pdb2Y4I/Pdb  0.728
2010 Hertz NT, Wang BT, Allen JJ, Zhang C, Dar AC, Burlingame AL, Shokat KM. Chemical genetic approach for kinase-substrate mapping by covalent capture of thiophosphopeptides and analysis by mass spectrometry. Current Protocols in Chemical Biology. 2: 15-36. PMID 23836541 DOI: 10.1002/9780470559277.Ch090201  0.744
2008 Kasap C, Hertz N, Makino D, Shokat K, Kuriyan J, Shah NP. Beyond the Gatekeeper: Imatinib- and Dasatinib-Resistant BCR-ABL/F317 Mutations Confer Cross-Resistance to VX-680 but Are Sensitive to a Structural Derivative of VX-680 Blood. 112: 725-725. DOI: 10.1182/Blood.V112.11.725.725  0.57
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