| Year |
Citation |
Score |
| 2023 |
Jones J, Correll DJ, Lechner SM, Jazic I, Miao X, Shaw D, Simard C, Osteen JD, Hare B, Beaton A, Bertoch T, Buvanendran A, Habib AS, Pizzi LJ, Pollak RA, et al. Selective Inhibition of Na1.8 with VX-548 for Acute Pain. The New England Journal of Medicine. 389: 393-405. PMID 37530822 DOI: 10.1056/NEJMoa2209870 |
0.381 |
|
| 2017 |
Osteen JD, Sampson K, Iyer V, Julius D, Bosmans F. Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607094 DOI: 10.1073/Pnas.1621263114 |
0.719 |
|
| 2016 |
Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. PMID 27281198 DOI: 10.1038/Nature17976 |
0.672 |
|
| 2013 |
Barro-Soria R, Osteen JD, Sampson KJ, Perez ME, Kass RS, Larsson HP. Long QT Mutations and KCNE1 β-Subunit Modulate S4 Movement in KCNQ1 Channel Biophysical Journal. 104: 357a. DOI: 10.1016/J.Bpj.2012.11.1982 |
0.747 |
|
| 2012 |
Osteen JD, Barro-Soria R, Robey S, Sampson KJ, Kass RS, Larsson HP. Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 109: 7103-8. PMID 22509038 DOI: 10.1073/Pnas.1201582109 |
0.711 |
|
| 2012 |
Glaaser IW, Osteen JD, Puckerin A, Sampson KJ, Jin X, Kass RS. Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation. Nature Communications. 3: 706. PMID 22426227 DOI: 10.1038/Ncomms1717 |
0.761 |
|
| 2012 |
Chan PJ, Osteen JD, Xiong D, Bohnen MS, Doshi D, Sampson KJ, Marx SO, Karlin A, Kass RS. Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1. The Journal of General Physiology. 139: 135-44. PMID 22250012 DOI: 10.1085/Jgp.201110672 |
0.767 |
|
| 2012 |
Osteen JD, Robey SH, Barro R, Rebolledo S, Sampson KJ, Larsson HP, Kass RS. Allosteric Properties of KCNQ1 (Kv7.1) Channel Gating Detected by Voltage Clamp Fluorometry Biophysical Journal. 102: 332a. DOI: 10.1016/J.Bpj.2011.11.1819 |
0.722 |
|
| 2012 |
Barro-Soria R, Osteen JD, Sampson KJ, Perez ME, Kass RS, Larsson P. Activation of Voltage Sensing Domains during KCNQ1 Channel Opening: Concerted or Independent? Biophysical Journal. 102: 332a. DOI: 10.1016/J.Bpj.2011.11.1817 |
0.776 |
|
| 2011 |
Wang K, Terrenoire C, Sampson KJ, Iyer V, Osteen JD, Lu J, Keller G, Kotton DN, Kass RS. Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry. The Journal of Physiology. 589: 6093-104. PMID 22025662 DOI: 10.1113/Jphysiol.2011.220863 |
0.706 |
|
| 2011 |
Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS. A novel Beta Subunit Mechanism in a Critical Heart K Channel: KCNE1 Alters the Voltage Sensor Movements Necessary to Open the KCNQ1 Channel Gate Biophysical Journal. 100: 29a-30a. DOI: 10.1016/J.Bpj.2010.12.365 |
0.744 |
|
| 2011 |
Glaaser IW, Osteen JD, Puckerin A, Kass RS. Mapping the Structure of the Cardiac Voltage-Gated Sodium Channel (Nav1.5) C-Terminus: Implications of An Lqt3 Mutant Biophysical Journal. 100: 15a. DOI: 10.1016/J.Bpj.2010.12.293 |
0.749 |
|
| 2011 |
Wang K, Terrenoire C, Sampson KJ, Osteen JD, Lu J, Gagliardi M, Keller G, Kass RS. Biophysical Characterization of Iks Channels in Cardiomyocytes Derived from Human Embryonic Stem Cells Reveals Insights Into Stoichiometry of KCNQ1-KCNE1 Complex Biophysical Journal. 100: 439a. DOI: 10.1016/J.Bpj.2010.12.2588 |
0.707 |
|
| 2010 |
Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS. KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate. Proceedings of the National Academy of Sciences of the United States of America. 107: 22710-5. PMID 21149716 DOI: 10.1073/Pnas.1016300108 |
0.757 |
|
| 2010 |
Osteen JD, Sampson KJ, Kass RS. The cardiac IKs channel, complex indeed. Proceedings of the National Academy of Sciences of the United States of America. 107: 18751-2. PMID 20974964 DOI: 10.1073/Pnas.1014150107 |
0.725 |
|
| 2010 |
Chan P, Osteen JD, Doshi D, Marx SO, Karlin A, Kass RS. Neighboring Alpha-Subunit (KCNQ1) Mutations with a Gain-of-Function IKs Phenotype Show Differential Dependence on Presence of Beta-Subunit (KCNE1) Biophysical Journal. 98: 121a. DOI: 10.1016/J.Bpj.2009.12.659 |
0.793 |
|
| 2008 |
Osteen JD, Mindell JA. Insights into the ClC-4 transport mechanism from studies of Zn2+ inhibition. Biophysical Journal. 95: 4668-75. PMID 18658230 DOI: 10.1529/Biophysj.108.137158 |
0.656 |
|
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