Year |
Citation |
Score |
2022 |
Odunuga OO, Oberhauser AF. Beyond Chaperoning: UCS Proteins Emerge as Regulators of Myosin-Mediated Cellular Processes. Sub-Cellular Biochemistry. 101: 189-211. PMID 36520308 DOI: 10.1007/978-3-031-14740-1_7 |
0.313 |
|
2020 |
Marszalek PE, Oberhauser AF. Meeting report - NSF-sponsored workshop 'Progress and Prospects of Single-Molecule Force Spectroscopy in Biological and Chemical Sciences'. Journal of Cell Science. 133. PMID 32817164 DOI: 10.1242/Jcs.251421 |
0.407 |
|
2020 |
Gaziova I, Moncrief T, Christian CJ, Villarreal M, Powell S, Lee H, Qadota H, White MA, Benian GM, Oberhauser AF. Mutational Analysis of the Structure and Function of the Chaperoning Domain of UNC-45B. Biophysical Journal. PMID 32755562 DOI: 10.1016/J.Bpj.2020.07.012 |
0.365 |
|
2020 |
Qadota H, Moody JC, Lesanpezeshki L, Moncrief T, Kitzler D, Bhat PD, Vanapalli SA, Oberhauser AF, Benian GM. A Region of UNC-89 (Obscurin) Lying between Two Protein Kinase Domains Is a Highly Elastic Spring Required for Proper Sarcomere Organization. Journal of Molecular Biology. PMID 32645312 DOI: 10.1016/J.Jmb.2020.06.024 |
0.445 |
|
2019 |
Renn JP, Bhattacharyya S, Bai H, He C, Li H, Oberhauser AF, Marko JF, Makarov DE, Matouschek A. Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force. Scientific Reports. 9: 11101. PMID 31366931 DOI: 10.1038/S41598-019-46525-W |
0.457 |
|
2018 |
Chen Z, Gu J, El Ayadi A, Oberhauser AF, Zhou J, Sousse LE, Finnerty CC, Herndon DN, Boor PJ. Effect of N-(2-aminoethyl) ethanolamine on hypertrophic scarring changes in vitro: Finding novel anti-fibrotic therapies. Toxicology and Applied Pharmacology. PMID 30248415 DOI: 10.1016/J.Taap.2018.09.026 |
0.307 |
|
2018 |
Bujalowski PJ, Nicholls P, Garza E, Oberhauser AF. The central domain of UNC-45 chaperone inhibits the myosin power stroke. Febs Open Bio. 8: 41-48. PMID 29321955 DOI: 10.1002/2211-5463.12346 |
0.378 |
|
2017 |
Oberhauser A, Nicholls P. Tracking Structural Changes in the UCS Domain of the Myosin Chaperone UNC-45 by Fluorescence Spectroscopy Biophysical Journal. 112: 491a. DOI: 10.1016/J.Bpj.2016.11.2659 |
0.361 |
|
2016 |
Nicholls P, Bujalowski P, Oberhauser A. The Unique Roles of UNC-45 Domains in Chaperoning Myosin Folding and Modulating Myosin Powerstroke Biophysical Journal. 110: 214a. DOI: 10.1016/J.Bpj.2015.11.1187 |
0.439 |
|
2015 |
Chen Z, Xu Y, Bujalowski P, Oberhauser AF, Boor PJ. N-(2-Aminoethyl) Ethanolamine Induced Morphological, Biochemical and Biophysical Alterations in Vascular Matrix Associated with Dissecting Aortic Aneurysm. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26443843 DOI: 10.1093/Toxsci/Kfv194 |
0.306 |
|
2015 |
Bujalowski PJ, Nicholls P, Barral JM, Oberhauser AF. Thermally-induced structural changes in an armadillo repeat protein suggest a novel thermosensor mechanism in a molecular chaperone Febs Letters. 589: 123-130. PMID 25436418 DOI: 10.1016/J.Febslet.2014.11.034 |
0.381 |
|
2014 |
Nicholls P, Bujalowski PJ, Epstein HF, Boehning DF, Barral JM, Oberhauser AF. Chaperone-mediated reversible inhibition of the sarcomeric myosin power stroke. Febs Letters. 588: 3977-81. PMID 25240199 DOI: 10.1016/J.Febslet.2014.09.013 |
0.327 |
|
2014 |
Bujalowski PJ, Nicholls P, Oberhauser AF. UNC-45B chaperone: the role of its domains in the interaction with the myosin motor domain. Biophysical Journal. 107: 654-61. PMID 25099804 DOI: 10.1016/J.Bpj.2014.05.045 |
0.43 |
|
2014 |
Nicholls P, Bujalowski P, Boehning D, Barral J, Oberhauser A. Molecular Chaperone Mediated Inhibition of the Myosin Power Stroke may be Critical for Sarcomere Assembly Biophysical Journal. 106: 766a. DOI: 10.1016/J.Bpj.2013.11.4213 |
0.363 |
|
2013 |
Xu M, Ma L, Bujalowski PJ, Qian F, Sutton RB, Oberhauser AF. Analysis of the REJ Module of Polycystin-1 Using Molecular Modeling and Force-Spectroscopy Techniques. Journal of Biophysics (Hindawi Publishing Corporation : Online). 2013: 525231. PMID 23762046 DOI: 10.1155/2013/525231 |
0.435 |
|
2013 |
Bujalowski PJ, Oberhauser AF. Tracking unfolding and refolding reactions of single proteins using atomic force microscopy methods. Methods (San Diego, Calif.). 60: 151-60. PMID 23523554 DOI: 10.1016/J.Ymeth.2013.03.010 |
0.495 |
|
2013 |
Bujalowski P, Nicholls P, Kaiser CM, Ma L, Epstein H, Oberhauser AF. Analysis of Myosin Motor Domain Interactions with its Chaperone UNC-45 at the Single Molecule Level Biophysical Journal. 104: 570a. DOI: 10.1016/J.Bpj.2012.11.3165 |
0.456 |
|
2012 |
El Ayadi A, Stieren ES, Barral JM, Oberhauser AF, Boehning D. Purification and aggregation of the amyloid precursor protein intracellular domain. Journal of Visualized Experiments : Jove. e4204. PMID 22952038 DOI: 10.3791/4204 |
0.4 |
|
2012 |
Kaiser CM, Bujalowski PJ, Ma L, Anderson J, Epstein HF, Oberhauser AF. Tracking UNC-45 chaperone-myosin interaction with a titin mechanical reporter. Biophysical Journal. 102: 2212-9. PMID 22824286 DOI: 10.1016/J.Bpj.2012.03.013 |
0.457 |
|
2012 |
Gong B, Ma L, Liu Y, Gong Q, Shelite T, Bouyer D, Boor PJ, Lee YS, Oberhauser A. Rickettsiae induce microvascular hyperpermeability via phosphorylation of VE-cadherins: evidence from atomic force microscopy and biochemical studies. Plos Neglected Tropical Diseases. 6: e1699. PMID 22720111 DOI: 10.1371/Journal.Pntd.0001699 |
0.347 |
|
2012 |
Ma L, Xu M, Oberhauser AF. Single-molecule force spectroscopy of polycystic kidney disease proteins Methods in Molecular Biology. 875: 297-310. PMID 22573448 DOI: 10.1007/978-1-61779-806-1_16 |
0.51 |
|
2012 |
Lu W, Negi SS, Oberhauser AF, Braun W. Engineering proteins with enhanced mechanical stability by force-specific sequence motifs. Proteins. 80: 1308-15. PMID 22274941 DOI: 10.1002/Prot.24027 |
0.5 |
|
2012 |
Bujalowski P, Ma L, Oberhauser A. Direct Quantification of the Effects of Osmolytes on Protein Unfolding and Refolding Pathways using AFM Techniques Biophysical Journal. 102: 55a. DOI: 10.1016/J.Bpj.2011.11.330 |
0.41 |
|
2011 |
Baldock C, Oberhauser AF, Ma L, Lammie D, Siegler V, Mithieux SM, Tu Y, Chow JY, Suleman F, Malfois M, Rogers S, Guo L, Irving TC, Wess TJ, Weiss AS. Shape of tropoelastin, the highly extensible protein that controls human tissue elasticity. Proceedings of the National Academy of Sciences of the United States of America. 108: 4322-7. PMID 21368178 DOI: 10.1073/Pnas.1014280108 |
0.419 |
|
2011 |
Oberhauser A, Kaiser C, Ma L, Epstein H. Titin Domains as Mechanical Reporters of UNC-45 Mediated Myosin Folding Biophysical Journal. 100: 482a. DOI: 10.1016/J.Bpj.2010.12.2826 |
0.414 |
|
2011 |
Ma L, Xu M, Oberhauser A. Naturally Occurring Osmolytes Modulate the Nano-Mechanical Properties of Polycystic Kidney Disease (PKD) Domains Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.2825 |
0.457 |
|
2011 |
Lu W, Oberhauser AF, Braun W. Designing Novel Proteins with Enhanced Mechanical Strengths Biophysical Journal. 100: 162a. DOI: 10.1016/J.Bpj.2010.12.1101 |
0.538 |
|
2010 |
Ma L, Xu M, Oberhauser AF. Naturally occurring osmolytes modulate the nanomechanical properties of polycystic kidney disease domains. The Journal of Biological Chemistry. 285: 38438-43. PMID 20937836 DOI: 10.1074/Jbc.M110.183913 |
0.473 |
|
2010 |
Galera-Prat A, Gómez-Sicilia A, Oberhauser AF, Cieplak M, Carrión-Vázquez M. Understanding biology by stretching proteins: recent progress. Current Opinion in Structural Biology. 20: 63-9. PMID 20138503 DOI: 10.1016/J.Sbi.2010.01.003 |
0.439 |
|
2010 |
Xu M, Ma L, Oberhauser A. How Do Osmolytes affect the Stability of Polycystin-1 PKD Domains? Biophysical Journal. 98: 753a. DOI: 10.1016/J.Bpj.2009.12.4128 |
0.415 |
|
2009 |
Ma L, Xu M, Forman JR, Clarke J, Oberhauser AF. Naturally occurring mutations alter the stability of polycystin-1 polycystic kidney disease (PKD) domains. The Journal of Biological Chemistry. 284: 32942-9. PMID 19759016 DOI: 10.1074/Jbc.M109.021832 |
0.34 |
|
2009 |
Xiong G, Qadota H, Mercer KB, McGaha LA, Oberhauser AF, Benian GM. A LIM-9 (FHL)/SCPL-1 (SCP) complex interacts with the C-terminal protein kinase regions of UNC-89 (obscurin) in Caenorhabditis elegans muscle. Journal of Molecular Biology. 386: 976-88. PMID 19244614 DOI: 10.1016/J.Jmb.2009.01.016 |
0.371 |
|
2009 |
Fuson KL, Ma L, Sutton RB, Oberhauser AF. The c2 domains of human synaptotagmin 1 have distinct mechanical properties. Biophysical Journal. 96: 1083-90. PMID 19186144 DOI: 10.1016/J.Bpj.2008.10.025 |
0.471 |
|
2009 |
Garcia TI, Oberhauser AF, Braun W. Mechanical stability and differentially conserved physical-chemical properties of titin Ig-domains. Proteins. 75: 706-18. PMID 19003986 DOI: 10.1002/Prot.22281 |
0.736 |
|
2009 |
Ma L, Xu M, Oberhauser A. Pathogenic Mutations alter the Mechanical Stability of Polycystin-1 Immunoglobulin PKD Domains Biophysical Journal. 96: 642a. DOI: 10.1016/J.Bpj.2008.12.3395 |
0.449 |
|
2009 |
Xu M, Ma L, Odunuga O, Delgado E, Oberhauser A. Mechanical function and Biophysical Properties of the REJ region of Polycystin-1 Biophysical Journal. 96: 641a. DOI: 10.1016/J.Bpj.2008.12.3391 |
0.512 |
|
2008 |
Greene DN, Garcia T, Sutton RB, Gernert KM, Benian GM, Oberhauser AF. Single-molecule force spectroscopy reveals a stepwise unfolding of Caenorhabditis elegans giant protein kinase domains. Biophysical Journal. 95: 1360-70. PMID 18390597 DOI: 10.1529/Biophysj.108.130237 |
0.731 |
|
2008 |
Oberhauser AF, Carrión-Vázquez M. Mechanical biochemistry of proteins one molecule at a time. The Journal of Biological Chemistry. 283: 6617-21. PMID 18195002 DOI: 10.1074/Jbc.R700050200 |
0.508 |
|
2006 |
Miller E, Garcia T, Hultgren S, Oberhauser AF. The mechanical properties of E. coli type 1 pili measured by atomic force microscopy techniques. Biophysical Journal. 91: 3848-56. PMID 16950852 DOI: 10.1529/Biophysj.106.088989 |
0.735 |
|
2006 |
Bullard B, Garcia T, Benes V, Leake MC, Linke WA, Oberhauser AF. The molecular elasticity of the insect flight muscle proteins projectin and kettin. Proceedings of the National Academy of Sciences of the United States of America. 103: 4451-6. PMID 16537423 DOI: 10.1073/Pnas.0509016103 |
0.758 |
|
2006 |
Linke W, Bullard B, Leake M, Oberhauser A. Titin-like Ig/FN3 domains can refold fast and even under substantial force Journal of Biomechanics. 39: S40. DOI: 10.1016/S0021-9290(06)83035-6 |
0.404 |
|
2005 |
Qian F, Wei W, Germino G, Oberhauser A. The nanomechanics of polycystin-1 extracellular region. The Journal of Biological Chemistry. 280: 40723-30. PMID 16219758 DOI: 10.1074/Jbc.M509650200 |
0.514 |
|
2003 |
Marszalek PE, Oberhauser AF, Li H, Fernandez JM. The force-driven conformations of heparin studied with single molecule force microscopy. Biophysical Journal. 85: 2696-704. PMID 14507732 DOI: 10.1016/S0006-3495(03)74692-X |
0.672 |
|
2003 |
Carrion-Vazquez M, Li H, Lu H, Marszalek PE, Oberhauser AF, Fernandez JM. The mechanical stability of ubiquitin is linkage dependent. Nature Structural Biology. 10: 738-43. PMID 12923571 DOI: 10.1038/Nsb965 |
0.654 |
|
2002 |
Li H, Linke WA, Oberhauser AF, Carrion-Vazquez M, Kerkvliet JG, Lu H, Marszalek PE, Fernandez JM. Reverse engineering of the giant muscle protein titin. Nature. 418: 998-1002. PMID 12198551 DOI: 10.1038/Nature00938 |
0.623 |
|
2002 |
Oberhauser AF, Badilla-Fernandez C, Carrion-Vazquez M, Fernandez JM. The mechanical hierarchies of fibronectin observed with single-molecule AFM Journal of Molecular Biology. 319: 433-447. PMID 12051919 DOI: 10.1016/S0022-2836(02)00306-6 |
0.675 |
|
2002 |
Marszalek PE, Li H, Oberhauser AF, Fernandez JM. Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM Proceedings of the National Academy of Sciences of the United States of America. 99: 4278-4283. PMID 11917130 DOI: 10.1073/Pnas.072435699 |
0.654 |
|
2001 |
Li H, Oberhauser AF, Redick SD, Carrion-Vazquez M, Erickson HP, Fernandez JM. Multiple conformations of PEVK proteins detected by single-molecule techniques Proceedings of the National Academy of Sciences of the United States of America. 98: 10682-10686. PMID 11526214 DOI: 10.1073/Pnas.191189098 |
0.461 |
|
2001 |
Fernandez JM, Chu S, Oberhauser AF. RNA structure: Putting on hair(pins) Science. 292: 653-654. PMID 11330326 DOI: 10.1126/Science.1060884 |
0.5 |
|
2001 |
Oberhauser AF, Hansma PK, Carrion-Vazquez M, Fernandez JM. Stepwise unfolding of titin under force-clamp atomic force microscopy Proceedings of the National Academy of Sciences of the United States of America. 98: 468-472. PMID 11149943 DOI: 10.1073/Pnas.98.2.468 |
0.674 |
|
2000 |
Carrion-Vazquez M, Oberhauser AF, Fisher TE, Marszalek PE, Li H, Fernandez JM. Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering Progress in Biophysics and Molecular Biology. 74: 63-91. PMID 11106807 DOI: 10.1016/S0079-6107(00)00017-1 |
0.55 |
|
2000 |
Li H, Carrion-Vazquez M, Oberhauser AF, Marszalek PE, Fernandez JM. Point mutations alter the mechanical stability of immunoglobulin modules Nature Structural Biology. 7: 1117-1120. PMID 11101892 DOI: 10.1038/81964 |
0.439 |
|
2000 |
Fisher TE, Carrion-Vazquez M, Oberhauser AF, Li H, Marszalek PE, Fernandez JM. Single molecule force spectroscopy of modular proteins in the nervous system Neuron. 27: 435-446. PMID 11055427 DOI: 10.1016/S0896-6273(00)00055-6 |
0.304 |
|
2000 |
Marszalek PE, Greenleaf WJ, Li H, Oberhauser AF, Fernandez JM. Atomic force microscopy captures quantized plastic deformation in gold nanowires. Proceedings of the National Academy of Sciences of the United States of America. 97: 6282-6. PMID 10841533 DOI: 10.1073/Pnas.97.12.6282 |
0.401 |
|
2000 |
Li H, Oberhauser AF, Fowler SB, Clarke J, Fernandez JM. Atomic force microscopy reveals the mechanical design of a modular protein Proceedings of the National Academy of Sciences of the United States of America. 97: 6527-6531. PMID 10823913 DOI: 10.1073/Pnas.120048697 |
0.45 |
|
1999 |
Marszalek PE, Lu H, Li H, Carrion-Vazquez M, Oberhauser AF, Schulten K, Fernandez JM. Mechanical unfolding intermediates in titin modules Nature. 402: 100-103. PMID 10573426 DOI: 10.1038/47083 |
0.679 |
|
1999 |
Oberhauser AF, Marszalek PE, Carrion-Vazquez M, Fernandez JM. Single protein misfolding events captured by atomic force microscopy Nature Structural Biology. 6: 1025-1028. PMID 10542093 DOI: 10.1038/14907 |
0.653 |
|
1999 |
Fisher TE, Marszalek PE, Oberhauser AF, Carrion-Vazquez M, Fernandez JM. The micro-mechanics of single molecules studied with atomic force microscopy Journal of Physiology. 520: 5-14. PMID 10517795 DOI: 10.1111/J.1469-7793.1999.00005.X |
0.589 |
|
1999 |
Fisher TE, Oberhauser AF, Carrion-Vazquez M, Marszalek PE, Fernandez JM. The study of protein mechanics with the atomic force microscope Trends in Biochemical Sciences. 24: 379-384. PMID 10500301 DOI: 10.1016/S0968-0004(99)01453-X |
0.548 |
|
1999 |
Carrion-Vazquez M, Marszalek PE, Oberhauser AF, Fernandez JM. Atomic force microscopy captures length phenotypes in single proteins. Proceedings of the National Academy of Sciences of the United States of America. 96: 11288-92. PMID 10500169 DOI: 10.1073/Pnas.96.20.11288 |
0.481 |
|
1999 |
Marszalek PE, Pang YP, Li H, El Yazal J, Oberhauser AF, Fernandez JM. Atomic levers control pyranose ring conformations. Proceedings of the National Academy of Sciences of the United States of America. 96: 7894-8. PMID 10393918 DOI: 10.1073/Pnas.96.14.7894 |
0.394 |
|
1999 |
Carrion-Vazquez M, Oberhauser AF, Fowler SB, Marszalek PE, Broedel SE, Clarke J, Fernandez JM. Mechanical and chemical unfolding of a single protein: a comparison. Proceedings of the National Academy of Sciences of the United States of America. 96: 3694-9. PMID 10097099 DOI: 10.1073/Pnas.96.7.3694 |
0.509 |
|
1998 |
Marszalek PE, Oberhauser AF, Pang YP, Fernandez JM. Polysaccharide elasticity governed by chair-boat transitions of the glucopyranose ring. Nature. 396: 661-4. PMID 9872313 DOI: 10.1038/25322 |
0.601 |
|
1998 |
Oberhauser AF, Marszalek PE, Erickson HP, Fernandez JM. The molecular elasticity of the extracellular matrix protein tenascin. Nature. 393: 181-5. PMID 9603523 DOI: 10.1038/30270 |
0.685 |
|
1994 |
Monck JR, Oberhauser AF, Robinson IM, Fernandez JM. Neurotransmitter release through the exocytotic fusion pore Seminars in Neuroscience. 6: 177-185. DOI: 10.1006/Smns.1994.1023 |
0.337 |
|
1993 |
Oberhauser AF, Fernandez JM. Patch clamp studies of single intact secretory granules. Biophysical Journal. 65: 1844-52. PMID 7507717 DOI: 10.1016/S0006-3495(93)81246-3 |
0.303 |
|
1992 |
Oberhauser AF, Monck JR, Balch WE, Fernandez JM. Exocytotic fusion is activated by Rab3a peptides Nature. 360: 270-273. PMID 1331813 DOI: 10.1038/360270A0 |
0.351 |
|
1991 |
Monck JR, Oberhauser AF, Alvarez de Toledo G, Fernandez JM. Is swelling of the secretory granule matrix the force that dilates the exocytotic fusion pore? Biophysical Journal. 59: 39-47. PMID 2015389 DOI: 10.1016/S0006-3495(91)82196-8 |
0.703 |
|
1989 |
Behrens MI, Oberhauser A, Bezanilla F, Latorre R. Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers. Ion conduction and gating properties. The Journal of General Physiology. 93: 23-41. PMID 2536797 DOI: 10.1085/jgp.93.1.23 |
0.392 |
|
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