| Year |
Citation |
Score |
| 2023 |
Keeler SP, Wu K, Zhang Y, Mao D, Li M, Iberg CA, Austin SR, Glaser SA, Yantis J, Podgorny S, Brody SL, Chartock JR, Han Z, Byers DE, Romero AG, et al. A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 37847710 DOI: 10.1152/ajplung.00183.2023 |
0.308 |
|
| 2018 |
Damalanka VC, Han Z, Karmakar P, O'Donoghue AJ, La Greca F, Kim T, Pant S, Helander J, Klefström J, Craik CS, Janetka JW. Discovery of Selective Matriptase and Hepsin Serine Protease Inhibitors: Useful Chemical Tools for Cancer Cell Biology. Journal of Medicinal Chemistry. PMID 30571119 DOI: 10.1021/Acs.Jmedchem.8B01536 |
0.613 |
|
| 2017 |
Owusu BY, Thomas S, Venukadasula P, Han Z, Janetka JW, Galemmo RA, Klampfer L. Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation. Oncotarget. 8: 63014-63025. PMID 28968967 DOI: 10.18632/Oncotarget.18260 |
0.724 |
|
| 2017 |
Owusu BY, Thomas S, Venukadasula P, Han Z, Janetka JW, Galemmo RA, Klampfer L. Targeting the tumor-promoting microenvironment in MET-amplified NSCLC cells with a novel inhibitor of pro-HGF activation. Oncotarget. PMID 28624806 DOI: 10.18632/oncotarget.18260 |
0.708 |
|
| 2016 |
Mydock-McGrane L, Cusumano Z, Han Z, Binkley J, Kostakioti M, Hannan T, Pinkner JS, Klein RD, Kalas V, Crowley J, Rath NP, Hultgren SJ, Janetka JW. Anti-virulence C-mannoisdes as antibiotic-sparing, oral therapeutics for urinary tract infections. Journal of Medicinal Chemistry. PMID 27689912 DOI: 10.1021/Acs.Jmedchem.6B00948 |
0.644 |
|
| 2016 |
Han Z, Harris PK, Karmakar P, Kim T, Owusu BY, Wildman SA, Klampfer L, Janetka JW. α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer. Chemmedchem. PMID 26889658 DOI: 10.1002/Cmdc.201500600 |
0.788 |
|
| 2016 |
Jarvis C, Han Z, Kalas V, Klein R, Pinkner JS, Ford B, Binkley J, Cusumano CK, Cusumano Z, Mydock-McGrane L, Hultgren SJ, Janetka JW. Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI. Chemmedchem. PMID 26812660 DOI: 10.1002/Cmdc.201600006 |
0.655 |
|
| 2016 |
Liu F, Han Z, Karmakar P, Li T, Janetka JW, Lai A. DDIS-10. TARGETING HGF/MET IN GBM BY RESTORING SPINT2 FUNCTION Neuro-Oncology. 18: vi49-vi49. DOI: 10.1093/Neuonc/Now212.201 |
0.693 |
|
| 2016 |
Han Z, Harris PKW, Karmakar P, Kim T, Owusu BY, Wildman SA, Klampfer L, Janetka JW. Back Cover: α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer (ChemMedChem 6/2016) Chemmedchem. 11: 640-640. DOI: 10.1002/Cmdc.201600124 |
0.758 |
|
| 2016 |
Jarvis C, Han Z, Kalas V, Klein R, Pinkner JS, Ford B, Binkley J, Cusumano CK, Cusumano Z, Mydock-McGrane L, Hultgren SJ, Janetka JW. Cover Picture: Antivirulence Isoquinolone Mannosides: Optimization of the Biaryl Aglycone for FimH Lectin Binding Affinity and Efficacy in the Treatment of Chronic UTI (ChemMedChem 4/2016) Chemmedchem. 11: 351-351. DOI: 10.1002/Cmdc.201600045 |
0.588 |
|
| 2015 |
Franco FM, Jones DE, Harris PK, Han Z, Wildman SA, Jarvis CM, Janetka JW. Structure-based discovery of small molecule hepsin and HGFA protease inhibitors: Evaluation of potency and selectivity derived from distinct binding pockets. Bioorganic & Medicinal Chemistry. 23: 2328-43. PMID 25882520 DOI: 10.1016/J.Bmc.2015.03.072 |
0.744 |
|
| 2014 |
Han Z, Harris PK, Jones DE, Chugani R, Kim T, Agarwal M, Shen W, Wildman SA, Janetka JW. Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer. Acs Medicinal Chemistry Letters. 5: 1219-24. PMID 25408834 DOI: 10.1021/Ml500254R |
0.736 |
|
| 2014 |
Janetka J, Han Z, Harris P, Wildman S. Abstract 2523: Mechanism-based inhibitors of HGFA, matriptase and hepsin for breast cancer treatment Cancer Research. 74: 2523-2523. DOI: 10.1158/1538-7445.Am2014-2523 |
0.73 |
|
| 2012 |
Guiton PS, Cusumano CK, Kline KA, Dodson KW, Han Z, Janetka JW, Henderson JP, Caparon MG, Hultgren SJ. Combinatorial small-molecule therapy prevents uropathogenic Escherichia coli catheter-associated urinary tract infections in mice. Antimicrobial Agents and Chemotherapy. 56: 4738-45. PMID 22733070 DOI: 10.1128/Aac.00447-12 |
0.615 |
|
| 2012 |
Han Z, Pinkner JS, Ford B, Chorell E, Crowley JM, Cusumano CK, Campbell S, Henderson JP, Hultgren SJ, Janetka JW. Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides. Journal of Medicinal Chemistry. 55: 3945-59. PMID 22449031 DOI: 10.1021/Jm300165M |
0.66 |
|
| 2011 |
Cusumano CK, Pinkner JS, Han Z, Greene SE, Ford BA, Crowley JR, Henderson JP, Janetka JW, Hultgren SJ. Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Science Translational Medicine. 3: 109ra115. PMID 22089451 DOI: 10.1126/Scitranslmed.3003021 |
0.645 |
|
| 2010 |
Han Z, Pinkner JS, Ford B, Obermann R, Nolan W, Wildman SA, Hobbs D, Ellenberger T, Cusumano CK, Hultgren SJ, Janetka JW. Structure-based drug design and optimization of mannoside bacterial FimH antagonists. Journal of Medicinal Chemistry. 53: 4779-92. PMID 20507142 DOI: 10.1021/Jm100438S |
0.648 |
|
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