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Norman Matthew Ellinwood, Ph.D., D.V.M. - Publications

Affiliations: 
2004- Animal Science Iowa State University, Ames, IA, United States 
Area:
Physiology, Reproduction, Immunity, Molecular Biology, Comparative Genetics, Gene Therapy
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20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Ellinwood NM, Valentine BN, Hess AS, Jens JK, Snella EM, Jamil M, Hostetter SJ, Jeffery ND, Smith JD, Millman ST, Parsons RL, Butt MT, Chandra S, Egeland MT, Assis AB, et al. Tralesinidase alfa enzyme replacement therapy prevents disease manifestations in a canine model of mucopolysaccharidosis type IIIB. The Journal of Pharmacology and Experimental Therapeutics. PMID 35717448 DOI: 10.1124/jpet.122.001119  0.406
2020 Egeland MT, Tarczyluk-Wells MM, Asmar MM, Adintori EG, Lawrence R, Snella EM, Jens JK, Crawford BE, Wait JCM, McCullagh E, Pinkstaff J, Cooper JD, Ellinwood NM. Central nervous system pathology in preclinical MPS IIIB dogs reveals progressive changes in clinically relevant brain regions. Scientific Reports. 10: 20365. PMID 33230178 DOI: 10.1038/s41598-020-77032-y  0.342
2020 Harm TA, Hostetter SJ, Nenninger AS, Valentine BN, Ellinwood NM, Smith JD. Temporospatial Development of Neuropathologic Findings in a Canine Model of Mucopolysaccharidosis IIIB. Veterinary Pathology. 300985820960128. PMID 33205707 DOI: 10.1177/0300985820960128  0.325
2017 Aronovich EL, Hyland KA, Hall BC, Bell JB, Olson ER, Rusten MU, Hunter DW, Ellinwood NM, McIvor RS, Hackett PB. Prolonged expression of secreted enzymes in dogs after liver-directed delivery of Sleeping Beauty transposons: implications for non-viral gene therapy of systemic disease. Human Gene Therapy. PMID 28530135 DOI: 10.1089/Hum.2017.004  0.391
2014 Wang RY, Aminian A, McEntee MF, Kan SH, Simonaro CM, Lamanna WC, Lawrence R, Ellinwood NM, Guerra C, Le SQ, Dickson PI, Esko JD. Intra-articular enzyme replacement therapy with rhIDUA is safe, well-tolerated, and reduces articular GAG storage in the canine model of mucopolysaccharidosis type I. Molecular Genetics and Metabolism. 112: 286-93. PMID 24951454 DOI: 10.1016/J.Ymgme.2014.05.015  0.322
2013 Vite CH, Nestrasil I, Mlikotic A, Jens JK, Snella EM, Gross W, Shapiro EG, Kovac V, Provenzale JM, Chen S, Le SQ, Kan SH, Banakar S, Wang RY, Haskins ME, ... Ellinwood NM, et al. Features of brain MRI in dogs with treated and untreated mucopolysaccharidosis type I. Comparative Medicine. 63: 163-73. PMID 23582423  0.629
2012 Dickson PI, Ellinwood NM, Brown JR, Witt RG, Le SQ, Passage MB, Vera MU, Crawford BE. Specific antibody titer alters the effectiveness of intrathecal enzyme replacement therapy in canine mucopolysaccharidosis I. Molecular Genetics and Metabolism. 106: 68-72. PMID 22402327 DOI: 10.1016/J.Ymgme.2012.02.003  0.326
2012 Ponder KP, O'Malley TM, Wang P, O'Donnell PA, Traas AM, Knox VW, Aguirre GA, Ellinwood NM, Metcalf JA, Wang B, Parkinson-Lawrence EJ, Sleeper MM, Brooks DA, Hopwood JJ, Haskins ME. Neonatal gene therapy with a gamma retroviral vector in mucopolysaccharidosis VI cats. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 898-907. PMID 22395531 DOI: 10.1038/mt.2012.9  0.657
2011 Vite CH, Wang P, Patel RT, Walton RM, Walkley SU, Sellers RS, Ellinwood NM, Cheng AS, White JT, O'Neill CA, Haskins M. Biodistribution and pharmacodynamics of recombinant human alpha-L-iduronidase (rhIDU) in mucopolysaccharidosis type I-affected cats following multiple intrathecal administrations. Molecular Genetics and Metabolism. 103: 268-74. PMID 21482164 DOI: 10.1016/J.Ymgme.2011.03.011  0.597
2011 Ellinwood NM, Ausseil J, Desmaris N, Bigou S, Liu S, Jens JK, Snella EM, Mohammed EE, Thomson CB, Raoul S, Joussemet B, Roux F, Chérel Y, Lajat Y, Piraud M, et al. Safe, efficient, and reproducible gene therapy of the brain in the dog models of Sanfilippo and Hurler syndromes. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 251-9. PMID 21139569 DOI: 10.1038/Mt.2010.265  0.665
2010 Dierenfeld AD, McEntee MF, Vogler CA, Vite CH, Chen AH, Passage M, Le S, Shah S, Jens JK, Snella EM, Kline KL, Parkes JD, Ware WA, Moran LE, Fales-Williams AJ, ... ... Ellinwood NM, et al. Replacing the enzyme alpha-L-iduronidase at birth ameliorates symptoms in the brain and periphery of dogs with mucopolysaccharidosis type I. Science Translational Medicine. 2: 60ra89. PMID 21123810 DOI: 10.1126/scitranslmed.3001380  0.421
2010 Dickson PI, Hanson S, McEntee MF, Vite CH, Vogler CA, Mlikotic A, Chen AH, Ponder KP, Haskins ME, Tippin BL, Le SQ, Passage MB, Guerra C, Dierenfeld A, Jens J, ... ... Ellinwood NM, et al. Early versus late treatment of spinal cord compression with long-term intrathecal enzyme replacement therapy in canine mucopolysaccharidosis type I. Molecular Genetics and Metabolism. 101: 115-22. PMID 20655780 DOI: 10.1016/j.ymgme.2010.06.020  0.565
2009 Lhériteau E, Libeau L, Stieger K, Deschamps JY, Mendes-Madeira A, Provost N, Lemoine F, Mellersh C, Ellinwood NM, Cherel Y, Moullier P, Rolling F. The RPGRIP1-deficient dog, a promising canine model for gene therapy. Molecular Vision. 15: 349-61. PMID 19223988  0.609
2007 Ellinwood NM, Colle MA, Weil MA, Casal ML, Vite CH, Wiemelt S, Hasson CW, O'Malley TM, He X, Prociuk U, Verot L, Melniczek JR, Lannon A, Aguirre GD, Knox VW, et al. Bone marrow transplantation for feline mucopolysaccharidosis I. Molecular Genetics and Metabolism. 91: 239-50. PMID 17482862 DOI: 10.1016/J.Ymgme.2007.03.001  0.59
2006 Ponder KP, Wang B, Wang P, Ma X, Herati R, Wang B, Cullen K, O'Donnell P, Ellinwood NM, Traas A, Primeau TM, Haskins ME. Mucopolysaccharidosis I cats mount a cytotoxic T lymphocyte response after neonatal gene therapy that can be blocked with CTLA4-Ig. Molecular Therapy : the Journal of the American Society of Gene Therapy. 14: 5-13. PMID 16698321 DOI: 10.1016/j.ymthe.2006.03.015  0.644
2006 Wang B, O'Malley TM, Xu L, Vite C, Wang P, O'Donnell PA, Ellinwood NM, Haskins ME, Ponder KP. Expression in blood cells may contribute to biochemical and pathological improvements after neonatal intravenous gene therapy for mucopolysaccharidosis VII in dogs. Molecular Genetics and Metabolism. 87: 8-21. PMID 16275036 DOI: 10.1016/j.ymgme.2005.08.014  0.649
2004 Ellinwood NM, Vite CH, Haskins ME. Gene therapy for lysosomal storage diseases: the lessons and promise of animal models. The Journal of Gene Medicine. 6: 481-506. PMID 15133760 DOI: 10.1002/jgm.581  0.633
2002 Xu L, Mango RL, Sands MS, Haskins ME, Ellinwood NM, Ponder KP. Evaluation of pathological manifestations of disease in mucopolysaccharidosis VII mice after neonatal hepatic gene therapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 745-58. PMID 12498771 DOI: 10.1006/mthe.2002.0809  0.657
2002 Ponder KP, Melniczek JR, Xu L, Weil MA, O'Malley TM, O'Donnell PA, Knox VW, Aguirre GD, Mazrier H, Ellinwood NM, Sleeper M, Maguire AM, Volk SW, Mango RL, Zweigle J, et al. Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs. Proceedings of the National Academy of Sciences of the United States of America. 99: 13102-7. PMID 12232044 DOI: 10.1073/pnas.192353499  0.676
2002 Xu L, Haskins ME, Melniczek JR, Gao C, Weil MA, O'Malley TM, O'Donnell PA, Mazrier H, Ellinwood NM, Zweigle J, Wolfe JH, Ponder KP. Transduction of hepatocytes after neonatal delivery of a Moloney murine leukemia virus based retroviral vector results in long-term expression of beta-glucuronidase in mucopolysaccharidosis VII dogs. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 141-53. PMID 11829521 DOI: 10.1006/mthe.2002.0527  0.627
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