Duncan J. Stewart, M.D. - Publications

Affiliations: 
Regenerative Medicine Program Ottawa Hospital Research Institute/University of Ottawa 
Area:
Endothelial biology, cardiovascular disease, cell and gene therapy
Website:
https://www.ohri.ca/profile/DuncanJStewart

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Banoei MM, McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Schlosser K, Fergusson DA, Winston BW. Metabolomics Analysis of Mesenchymal Stem Cell (MSC) Therapy in a Phase I Clinical Trial of Septic Shock: An Exploratory Study. Metabolites. 13. PMID 37999238 DOI: 10.3390/metabo13111142  0.468
2023 Tieu A, Stewart DJ, Chwastek D, Lansdell C, Burger D, Lalu MM. Biodistribution of mesenchymal stromal cell-derived extracellular vesicles administered during acute lung injury. Stem Cell Research & Therapy. 14: 250. PMID 37705086 DOI: 10.1186/s13287-023-03472-8  0.727
2022 Foster M, Fergusson DA, Hunniford V, Cardenas A, Castillo G, Yaworsky J, Mazer CD, Devereaux PJ, McIsaac DI, Stewart DJ, Presseau J, Lalu MM. Understanding potential barriers and enablers to a perioperative early phase cell therapy trial. Cytotherapy. PMID 35396169 DOI: 10.1016/j.jcyt.2021.08.008  0.734
2022 Lithopoulos MA, Strueby L, O'Reilly M, Zhong S, Möbius MA, Eaton F, Fung M, Hurskainen M, Cyr-Depauw C, Suen C, Xu L, Collins JJP, Vadivel A, Stewart DJ, Burger D, et al. Pulmonary and Neurologic Effects of Mesenchymal Stromal Cell Extracellular Vesicles in a Multifactorial Lung Injury Model. American Journal of Respiratory and Critical Care Medicine. PMID 35286238 DOI: 10.1164/rccm.202012-4520OC  0.342
2022 Vaka R, Khan S, Ye B, Risha Y, Parent S, Courtman D, Stewart DJ, Davis DR. Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury. Stem Cell Research & Therapy. 13: 20. PMID 35033181 DOI: 10.1186/s13287-021-02699-7  0.464
2021 Tieu A, Hu K, Gnyra C, Montroy J, Fergusson DA, Allan DS, Stewart DJ, Thébaud B, Lalu MM. Mesenchymal stromal cell extracellular vesicles as therapy for acute and chronic respiratory diseases: A meta-analysis. Journal of Extracellular Vesicles. 10: e12141. PMID 34596349 DOI: 10.1002/jev2.12141  0.752
2021 Florian M, Wang JP, Deng Y, Souza-Moreira L, Stewart DJ, Mei SHJ. Gene engineered mesenchymal stem cells: greater transgene expression and efficacy with minicircle vs. plasmid DNA vectors in a mouse model of acute lung injury. Stem Cell Research & Therapy. 12: 184. PMID 33726829 DOI: 10.1186/s13287-021-02245-5  0.35
2020 Jacques E, Hosoyama K, Biniam B, Eren Cimenci C, Sedlakova V, Steeves AJ, Variola F, Davis DR, Stewart DJ, Suuronen EJ, Alarcon EI. Collagen-Based Microcapsules As Therapeutic Materials for Stem Cell Therapies in Infarcted Myocardium. Acs Biomaterials Science & Engineering. 6: 4614-4622. PMID 33455166 DOI: 10.1021/acsbiomaterials.0c00245  0.314
2020 McGinn R, Fergusson DA, Stewart DJ, Kristof AS, Barron CC, Thebaud B, McIntyre L, Stacey D, Liepmann M, Dodelet-Devillers A, Zhang H, Renlund R, Lilley E, Downey GP, Brown EG, et al. Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians. Critical Care Medicine. PMID 33332817 DOI: 10.1097/CCM.0000000000004734  0.731
2020 Thavorn K, van Katwyk S, Krahn M, Mei SHJ, Stewart DJ, Fergusson D, Coyle D, McIntyre L. Value of mesenchymal stem cell therapy for patients with septic shock: an early health economic evaluation. International Journal of Technology Assessment in Health Care. 1-8. PMID 33059782 DOI: 10.1017/S0266462320000781  0.458
2020 Tieu A, Lalu MM, Slobodian M, Gnyra C, Fergusson DA, Montroy J, Burger D, Stewart DJ, Allan DS. An Analysis of Mesenchymal Stem Cell-Derived Extracellular Vesicles for Preclinical Use. Acs Nano. PMID 32697573 DOI: 10.1021/Acsnano.0C01363  0.757
2020 Varkouhi AK, Monteiro APT, Tsoporis JN, Mei SHJ, Stewart DJ, Dos Santos CC. Genetically Modified Mesenchymal Stromal/Stem Cells: Application in Critical Illness. Stem Cell Reviews and Reports. PMID 32671645 DOI: 10.1007/s12015-020-10000-1  0.357
2020 Tieu A, Stewart DJ, Lalu MM. Mesenchymal Stem Cell-Derived Extracellular Vesicles: Good Things Come in Small Packages. Critical Care Medicine. 48: 1095-1097. PMID 32568911 DOI: 10.1097/CCM.0000000000004368  0.708
2020 Thompson M, Mei SHJ, Wolfe D, Champagne J, Fergusson D, Stewart DJ, Sullivan KJ, Doxtator E, Lalu M, English SW, Granton J, Hutton B, Marshall J, Maybee A, Walley KR, et al. Cell therapy with intravascular administration of mesenchymal stromal cells continues to appear safe: An updated systematic review and meta-analysis. Eclinicalmedicine. 19: 100249. PMID 31989101 DOI: 10.1016/J.Eclinm.2019.100249  0.601
2019 Tieu A, Slobodian M, Fergusson DA, Montroy J, Burger D, Stewart DJ, Shorr R, Allan DS, Lalu MM. Methods and efficacy of extracellular vesicles derived from mesenchymal stromal cells in animal models of disease: a preclinical systematic review protocol. Systematic Reviews. 8: 322. PMID 31831057 DOI: 10.1186/S13643-019-1242-Y  0.763
2019 Tan Y, Salkhordeh M, Wang JP, McRae A, Souza-Moreira L, McIntyre L, Stewart DJ, Mei SHJ. Thawed Mesenchymal Stem Cell Product Shows Comparable Immunomodulatory Potency to Cultured Cells In Vitro and in Polymicrobial Septic Animals. Scientific Reports. 9: 18078. PMID 31792313 DOI: 10.1038/s41598-019-54462-x  0.315
2019 Lalu MM, Montroy J, Dowlatshahi D, Hutton B, Juneau P, Wesch N, Y Zhang S, McGinn R, Corbett D, Stewart DJ, A Fergusson D. From the Lab to Patients: a Systematic Review and Meta-Analysis of Mesenchymal Stem Cell Therapy for Stroke. Translational Stroke Research. PMID 31654281 DOI: 10.1007/S12975-019-00736-5  0.739
2019 Fergusson DA, Avey MT, Barron CC, Bocock M, Biefer KE, Boet S, Bourque SL, Conic I, Chen K, Dong YY, Fox GM, George RB, Goldenberg NM, Gragasin FS, Harsha P, ... ... Stewart DJ, et al. Reporting preclinical anesthesia study (REPEAT): Evaluating the quality of reporting in the preclinical anesthesiology literature. Plos One. 14: e0215221. PMID 31120888 DOI: 10.1371/Journal.Pone.0215221  0.715
2019 Suen CM, Stewart DJ, Montroy J, Welsh C, Levac B, Wesch N, Zhai A, Fergusson D, McIntyre L, Lalu MM. Regenerative cell therapy for pulmonary arterial hypertension in animal models: a systematic review. Stem Cell Research & Therapy. 10: 75. PMID 30841915 DOI: 10.1186/S13287-019-1172-6  0.736
2019 Schlosser K, Wang JP, Dos Santos C, Walley KR, Marshall J, Fergusson DA, Winston BW, Granton J, Watpool I, Stewart DJ, McIntyre LA, Mei SHJ. Effects of Mesenchymal Stem Cell Treatment on Systemic Cytokine Levels in a Phase 1 Dose Escalation Safety Trial of Septic Shock Patients. Critical Care Medicine. PMID 30720538 DOI: 10.1097/Ccm.0000000000003657  0.511
2018 Lalu MM, Mazzarello S, Zlepnig J, Dong YYR, Montroy J, McIntyre L, Devereaux PJ, Stewart DJ, David Mazer C, Barron CC, McIsaac DI, Fergusson DA. Safety and Efficacy of Adult Stem Cell Therapy for Acute Myocardial Infarction and Ischemic Heart Failure (SafeCell Heart): A Systematic Review and Meta-Analysis. Stem Cells Translational Medicine. PMID 30255989 DOI: 10.1002/Sctm.18-0120  0.766
2017 Barron CC, Lalu MM, Stewart DJ, Fergusson D, Yang H, Moher D, Liu P, Mazer D, Devereaux PJ, McIntyre L. Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol. Systematic Reviews. 6: 226. PMID 29116020 DOI: 10.1186/S13643-017-0601-9  0.757
2017 McIntyre LA, Stewart DJ, Mei SHJ, Courtman D, Watpool I, Granton J, Marshall J, Dos Santos C, Walley KR, Winston BW, Schlosser K, Fergusson DA. Cellular Immunotherapy for Septic Shock (CISS): A Phase I Clinical Trial. American Journal of Respiratory and Critical Care Medicine. PMID 28960096 DOI: 10.1164/Rccm.201705-1006Oc  0.482
2016 Lalu MM, Sullivan KJ, Mei SH, Moher D, Straus A, Fergusson DA, Stewart DJ, Jazi M, MacLeod M, Winston B, Marshall J, Hutton B, Walley KR, McIntyre L. Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial. Elife. 5. PMID 27870924 DOI: 10.7554/Elife.17850  0.766
2016 Avey MT, Moher D, Sullivan KJ, Fergusson D, Griffin G, Grimshaw JM, Hutton B, Lalu MM, Macleod M, Marshall J, Mei SH, Rudnicki M, Stewart DJ, Turgeon AF, McIntyre L, et al. The Devil Is in the Details: Incomplete Reporting in Preclinical Animal Research. Plos One. 11: e0166733. PMID 27855228 DOI: 10.1371/Journal.Pone.0166733  0.728
2016 Mei SH, Dos Santos C, Stewart D. Advances in Stem Cell and Cell-Based Gene Therapy Approaches for Experimental Acute Lung Injury: A Review of Preclinical Studies. Human Gene Therapy. PMID 27531647 DOI: 10.1089/hum.2016.063  0.443
2016 Suen CM, Zhai A, Lalu MM, Welsh C, Levac BM, Fergusson D, McIntyre L, Stewart DJ. Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol. Systematic Reviews. 5: 89. PMID 27225668 DOI: 10.1186/S13643-016-0265-X  0.775
2016 McIntyre LA, Moher D, Fergusson DA, Sullivan KJ, Mei SH, Lalu M, Marshall J, Mcleod M, Griffin G, Grimshaw J, Turgeon A, Avey MT, Rudnicki MA, Jazi M, Fishman J, ... Stewart DJ, et al. Efficacy of Mesenchymal Stromal Cell Therapy for Acute Lung Injury in Preclinical Animal Models: A Systematic Review. Plos One. 11: e0147170. PMID 26821255 DOI: 10.1371/Journal.Pone.0147170  0.601
2015 Ho MS, Mei SH, Stewart DJ. The Immunomodulatory and Therapeutic Effects of Mesenchymal Stromal Cells for Acute Lung Injury and Sepsis. Journal of Cellular Physiology. PMID 25913273 DOI: 10.1002/jcp.25028  0.483
2014 Gomberg-Maitland M, Bull TM, Saggar R, Barst RJ, Elgazayerly A, Fleming TR, Grimminger F, Rainisio M, Stewart DJ, Stockbridge N, Ventura C, Ghofrani AH, Rubin LJ. [New trial designs and potential therapies for pulmonary artery hypertension]. TüRk Kardiyoloji DerneğI ArşIvi : TüRk Kardiyoloji DerneğInin YayıN OrganıDıR. 42: 106-18. PMID 25697038  0.31
2014 Foster WS, Suen CM, Stewart DJ. Regenerative cell and tissue-based therapies for pulmonary arterial hypertension. The Canadian Journal of Cardiology. 30: 1350-60. PMID 25442435 DOI: 10.1016/j.cjca.2014.08.022  0.401
2014 Noiseux N, Marquis-Gravel G, Mansour S, Shahzad U, Stewart DJ, Yau TM. The current state of stem cell therapeutics: Canadian approaches in the international context. The Canadian Journal of Cardiology. 30: 1361-9. PMID 25249498 DOI: 10.1016/J.Cjca.2014.04.031  0.502
2014 Lalu MM, Moher D, Marshall J, Fergusson D, Mei SH, Macleod M, Griffin G, Turgeon AF, Rudnicki M, Fishman J, Avey MT, Skidmore B, Grimshaw JM, Stewart DJ, Singh K, et al. Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol. Systematic Reviews. 3: 48. PMID 24887266 DOI: 10.1186/2046-4053-3-48  0.765
2014 Lalu MM, Barron CC, Stewart DJ, McIntyre LL. Adult stem cells: potential implications for perioperative medicine. Canadian Journal of Anaesthesia = Journal Canadien D'AnesthéSie. 61: 299-305. PMID 24510734 DOI: 10.1007/s12630-014-0121-1  0.7
2014 Liles WC, Matthay MA, Dos Santos CC, Weiss DJ, Stewart DJ. Mesenchymal stromal (stem) cell therapy: an emerging immunomodulatory strategy for the adjunctive treatment of sepsis. American Journal of Respiratory and Critical Care Medicine. 189: 363-4. PMID 24484339 DOI: 10.1164/Rccm.201307-1272Le  0.311
2013 Gomberg-Maitland M, Bull TM, Saggar R, Barst RJ, Elgazayerly A, Fleming TR, Grimminger F, Rainisio M, Stewart DJ, Stockbridge N, Ventura C, Ghofrani AH, Rubin LJ. New trial designs and potential therapies for pulmonary artery hypertension. Journal of the American College of Cardiology. 62: D82-91. PMID 24355645 DOI: 10.1016/j.jacc.2013.10.026  0.31
2013 Suen CM, Mei SH, Kugathasan L, Stewart DJ. Targeted delivery of genes to endothelial cells and cell- and gene-based therapy in pulmonary vascular diseases. Comprehensive Physiology. 3: 1749-79. PMID 24265244 DOI: 10.1002/cphy.c120034  0.301
2013 Maron-Gutierrez T, Silva JD, Asensi KD, Bakker-Abreu I, Shan Y, Diaz BL, Goldenberg RC, Mei SH, Stewart DJ, Morales MM, Rocco PR, Dos Santos CC. Effects of mesenchymal stem cell therapy on the time course of pulmonary remodeling depend on the etiology of lung injury in mice. Critical Care Medicine. 41: e319-33. PMID 23760104 DOI: 10.1097/CCM.0b013e31828a663e  0.347
2012 Lalu MM, McIntyre L, Pugliese C, Fergusson D, Winston BW, Marshall JC, Granton J, Stewart DJ. Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials. Plos One. 7: e47559. PMID 23133515 DOI: 10.1371/Journal.Pone.0047559  0.769
2012 Lalu MM, McIntyre LL, Stewart DJ. Mesenchymal stromal cells: cautious optimism for their potential role in the treatment of acute lung injury. Critical Care Medicine. 40: 1373-5. PMID 22425851 DOI: 10.1097/CCM.0b013e31824317f7  0.707
2011 Stewart DJ, Mei SH. Cell-based therapies for lung vascular diseases: lessons for the future. Proceedings of the American Thoracic Society. 8: 535-40. PMID 22052933 DOI: 10.1513/pats.201105-035MW  0.46
2011 Davis DR, Stewart DJ. Autologous cell therapy for cardiac repair. Expert Opinion On Biological Therapy. 11: 489-508. PMID 21303269 DOI: 10.1517/14712598.2011.556615  0.313
2008 Ward MR, Stewart DJ, Kutryk MJ. Endothelial progenitor cell therapy for the treatment of coronary disease, acute MI, and pulmonary arterial hypertension: current perspectives. Catheterization and Cardiovascular Interventions : Official Journal of the Society For Cardiac Angiography & Interventions. 70: 983-98. PMID 18044749 DOI: 10.1002/ccd.21302  0.46
2007 Mei SH, McCarter SD, Deng Y, Parker CH, Liles WC, Stewart DJ. Prevention of LPS-induced acute lung injury in mice by mesenchymal stem cells overexpressing angiopoietin 1. Plos Medicine. 4: e269. PMID 17803352 DOI: 10.1371/journal.pmed.0040269  0.314
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