Benjamin M. Akiyama, Ph.D.

Affiliations: 
Molecular Cell and Developmental Biology University of California, Santa Cruz, Santa Cruz, CA, United States 
Area:
structure and function of the telomerase ribonucleoprotein
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"Benjamin Akiyama"
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Michael David Stone grad student 2014 UC Santa Cruz
 (Assembly and dynamics of the Tetrahymena thermophila telomerase holoenzyme.)
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Publications

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Graham ME, Merrick C, Akiyama BM, et al. (2023) Zika virus dumbbell-1 structure is critical for sfRNA presence and cytopathic effect during infection. Mbio. e0110823
Akiyama BM, Graham ME, O Donoghue Z, et al. (2021) Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication. Nucleic Acids Research. 49: 7122-7138
Akiyama BM, Graham ME, O Donoghue Z, et al. (2021) Three-dimensional structure of a flavivirus dumbbell RNA reveals molecular details of an RNA regulator of replication. Nucleic Acids Research. 49: 7122-7138
Jones RA, Steckelberg AL, Vicens Q, et al. (2020) Different tertiary interactions create the same important 3-D features in a distinct flavivirus xrRNA. Rna (New York, N.Y.)
Steckelberg AL, Akiyama BM, Costantino DA, et al. (2018) A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure. Proceedings of the National Academy of Sciences of the United States of America
Akiyama BM, Laurence HM, Massey AR, et al. (2016) Zika virus produces noncoding RNAs using a multi-pseudoknot structure that confounds a cellular exonuclease. Science (New York, N.Y.). 354: 1148-1152
Akiyama BM, Eiler D, Kieft JS. (2016) Structured RNAs that evade or confound exonucleases: function follows form. Current Opinion in Structural Biology. 36: 40-47
Jansson LI, Akiyama BM, Ooms A, et al. (2015) Structural basis of template-boundary definition in Tetrahymena telomerase. Nature Structural & Molecular Biology
Akiyama BM, Parks JW, Stone MD. (2015) The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids. Nucleic Acids Research. 43: 5537-49
Akiyama BM, Stone MD. (2014) Direct Visualization of DNA Dynamics During the Telomerase Catalytic Cycle Reveals the Function of a Conserved Telomerase Domain Biophysical Journal. 106: 429a-430a
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