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Tze H. Charn, Ph.D.

Affiliations: 
2010 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
steroid hormones
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"Tze Charn"
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John A. Katzenellenbogen grad student 2010 UIUC
 (An integrated network of estrogen receptors alpha and beta, and coregulators, for deciphering estrogen signaling in breast cancer cells.)

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Publications

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Madak-Erdogan Z, Charn TH, Jiang Y, et al. (2017) Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Molecular Systems Biology. 13: 929
Madak-Erdogan Z, Charn TH, Jiang Y, et al. (2013) Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators. Molecular Systems Biology. 9: 676
Stender JD, Stossi F, Funk CC, et al. (2011) The estrogen-regulated transcription factor PITX1 coordinates gene-specific regulation by estrogen receptor-alpha in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 25: 1699-709
Li Y, Li Y, Wedrén S, et al. (2011) Genetic variation of ESR1 and its co-activator PPARGC1B is synergistic in augmenting the risk of estrogen receptor-positive breast cancer. Breast Cancer Research : Bcr. 13: R10
Stender JD, Kim K, Charn TH, et al. (2010) Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation. Molecular and Cellular Biology. 30: 3943-55
Charn TH, Liu ET, Chang EC, et al. (2010) Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection. Molecular Endocrinology (Baltimore, Md.). 24: 47-59
Barnett DH, Sheng S, Charn TH, et al. (2008) Estrogen receptor regulation of carbonic anhydrase XII through a distal enhancer in breast cancer. Cancer Research. 68: 3505-15
Chang EC, Charn TH, Park SH, et al. (2008) Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding. Molecular Endocrinology (Baltimore, Md.). 22: 1032-43
Lin CY, Vega VB, Thomsen JS, et al. (2007) Whole-genome cartography of estrogen receptor alpha binding sites. Plos Genetics. 3: e87
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