Liangcai Gu, Ph.D.
Affiliations: | 2008 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
cryptophycin anticancer drugsGoogle:
"Liangcai Gu"Mean distance: 8.36 | S | N | B | C | P |
Parents
Sign in to add mentorDavid H. Sherman | grad student | 2008 | University of Michigan | |
(Biosynthetic innovation on a polyketide assembly line: Biochemical studies of curacin A pathway.) |
Children
Sign in to add traineeJonathan Cheng | research scientist | 2015-2018 | University of Washington (Neurotree) |
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Publications
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Khare D, Hale WA, Tripathi A, et al. (2015) Structural Basis for Cyclopropanation by a Unique Enoyl-Acyl Carrier Protein Reductase. Structure (London, England : 1993) |
Liu B, Xue Y, Zhao W, et al. (2015) Three-dimensional super-resolution protein localization correlated with vitrified cellular context. Scientific Reports. 5: 13017 |
Li J, Gu L, Aach J, et al. (2014) Improved cell-free RNA and protein synthesis system. Plos One. 9: e106232 |
Gehret JJ, Gu L, Geders TW, et al. (2012) Structure and activity of DmmA, a marine haloalkane dehalogenase. Protein Science : a Publication of the Protein Society. 21: 239-48 |
Busche A, Gottstein D, Hein C, et al. (2012) Characterization of molecular interactions between ACP and halogenase domains in the Curacin A polyketide synthase. Acs Chemical Biology. 7: 378-86 |
Gu L, Eisman EB, Dutta S, et al. (2011) Tandem acyl carrier proteins in the curacin biosynthetic pathway promote consecutive multienzyme reactions with a synergistic effect. Angewandte Chemie (International Ed. in English). 50: 2795-8 |
Gehret JJ, Gu L, Gerwick WH, et al. (2011) Terminal alkene formation by the thioesterase of curacin A biosynthesis: structure of a decarboxylating thioesterase. The Journal of Biological Chemistry. 286: 14445-54 |
Khare D, Wang B, Gu L, et al. (2010) Conformational switch triggered by alpha-ketoglutarate in a halogenase of curacin A biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 14099-104 |
Gu L, Wang B, Kulkarni A, et al. (2009) Polyketide decarboxylative chain termination preceded by o-sulfonation in curacin a biosynthesis. Journal of the American Chemical Society. 131: 16033-5 |
Gu L, Wang B, Kulkarni A, et al. (2009) Metamorphic enzyme assembly in polyketide diversification. Nature. 459: 731-5 |