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Farshid Guilak, Ph.D.

Affiliations: 
Orthopaedic Surgery Washington University School of medicine in Saint Louis 
Area:
biomechanics, mechanobiology, regenerative medicine, osteoarthritis, biomedical engineering
Website:
https://orthopaedicresearch.wustl.edu/labs/farshid-guilak/
Google:
"Farshid Guilak"
Bio:

https://regenerativemedicine.wustl.edu/people/farshid-guilak-phd/
https://scholar.google.com/citations?user=CWj6pVcAAAAJ&hl=en
https://www.proquest.com/openview/4c29ac7c273fd9de7a046566f3daec0e/1

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Parents

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Van C. Mow grad student 1992 Columbia (E-Tree)
 (Cell-matrix interactions and metabolic changes in articular cartilage under compression)

Children

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Jonathan Brunger grad student Duke
Katherine Glass grad student Duke
Kelly Kimmerling grad student Duke
Robert J. Nims grad student Washington University School of Medicine (BME Tree)
Christopher O'Conor grad student UNC Chapel Hill
Christopher Rowland grad student Duke
Johannah Sanchez-Adams grad student Washington University School of medicine in Saint Louis (E-Tree)
Andrea Schwartz grad student Washington University School of medicine in Saint Louis (Chemistry Tree)
Chia-Lung Wu grad student Duke
Inchan Youn grad student KIST
Wendy R. Trickey grad student 2000 Duke
Geoffrey R. Erickson grad student 2001 Duke
Leonidas G. Alexopoulos grad student 2004 Duke
Scott E. Pritchard grad student 2005 Duke
Holly A. Leddy grad student 2007 Duke
Bradley T. Estes grad student 2008 Duke
Susan E. Christensen grad student 2009 Duke
Franklin T. Moutos grad student 2009 Duke
John D. Finan grad student 2010 Duke
Ned W. Garrigues grad student 2011 Duke
Brian O. Diekman grad student 2012 Duke
Rebecca E. Wilusz grad student 2013 Duke
Hani A. Awad post-doc Rochester (E-Tree)
Kelsey H. Collins post-doc Washington University School of Medicine (E-Tree)
Eric Darling post-doc Duke (BME Tree)
Christopher L. Gilchrist post-doc Washington University School of medicine in Saint Louis (BME Tree)
Timothy M Griffin post-doc Duke Medical School
Natalia Harasimowicz post-doc Washington University School of Medicine
Natalie Kelly post-doc Washington University School of Medicine (E-Tree)
Dianne Little post-doc Washington University School of medicine in Saint Louis (Cell Biology Tree)
Oswaldo A. Lozoya Iniguez post-doc Washington University School of medicine in Saint Louis (BME Tree)
Kristen Moffat post-doc Columbia
Shirley Nina Tang post-doc Washington University School of Medicine
Vincent P. Willard post-doc Duke (E-Tree)
Whasil Lee post-doc 2011-2018 Duke Medical School (E-Tree)

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Publications

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Marushack GK, Savadipour A, Tang R, et al. (2025) Polyunsaturated fatty acids suppress PIEZO ion channel mechanotransduction in articular chondrocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 39: e70290
Libke ML, Cunningham DJ, Furman BD, et al. (2024) Mode of injury and level of synovitis alter inflammatory chondrocyte gene expression and associated pathways. Scientific Reports. 14: 28917
Klimak M, Cimino A, Lenz KL, et al. (2024) Engineered self-regulating macrophages for targeted anti-inflammatory drug delivery. Arthritis Research & Therapy. 26: 190
Tang R, Harasymowicz NS, Wu CL, et al. (2024) Gene therapy for prevents obesity-induced metabolic dysfunction, cellular senescence, and osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America. 121: e2402954121
Melrose J, Guilak F. (2024) Diverse and multifunctional roles for perlecan () in repair of the intervertebral disc. Jor Spine. 7: e1362
Nims R, Palmer DR, Kassab J, et al. (2024) The chondrocyte "mechanome": Activation of the mechanosensitive ion channels TRPV4 and PIEZO1 drives unique transcriptional signatures. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23778
Klimak M, Cimino A, Lenz K, et al. (2024) Engineered Self-Regulating Macrophages for Targeted Anti-inflammatory Drug Delivery. Research Square
Shen KC, Collins KH, Ferey JLA, et al. (2024) Excess Intramyocellular Lipid Does Not Affect Muscle Fiber Biophysical Properties in Mice or People with Metabolically Abnormal Obesity. Diabetes
Jenkins TL, Sarmiento Huertas PA, Umemori K, et al. (2023) Tendon-derived matrix crosslinking techniques for electrospun multi-layered scaffolds. Journal of Biomedical Materials Research. Part A
Savadipour A, Nims RJ, Rashidi N, et al. (2023) Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221958120
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